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AN JIANBO  安 健博

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An Jianbo  安 健博

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Researcher Number 40723771
Other IDs
Affiliation (Current) 2025: 秋田大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help 2019 – 2023: 秋田大学, 医学系研究科, 助教
2018: 東京医科歯科大学, 難治疾患研究所, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49010:Pathological biochemistry-related
Keywords
Principal Investigator
動脈硬化 / マクロファージ / 動脈硬化症 / 空間的トランスクリプトーム解析 / Galectin-7 / 免疫抑制 / がん微小環境 / 転移 / MDSCs / G-CSF … More / 扁平上皮癌 / 炎症 / 炎症応答 / Interferon / CCR4-NOT / 脂肪萎縮症 / MRTF-A / 細胞増殖 / MKL1 Less
  • Research Projects

    (3 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (5 People)
  •  癌の転移・再発における細胞外Galectin-Xを介した免疫抑制機構の解明Principal Investigator

    • Principal Investigator
      安 健博
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Akita University
  •  The role of CCR4-NOT in the development of atherosclerosisPrincipal Investigator

    • Principal Investigator
      An Jianbo
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Akita University
  •  The role of macrophagic MKL1 in the pathogenesis of atherosclerosisPrincipal Investigator

    • Principal Investigator
      An Jianbo
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49010:Pathological biochemistry-related
    • Research Institution
      Akita University
      Tokyo Medical and Dental University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

  • [Journal Article] Squamous cell carcinoma‐derived <scp>G‐CSF</scp> promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation, associated with poor prognosis of the patients2023

    • Author(s)
      Kemuriyama Kohei、An Jianbo、Motoyama Satoru、Nagaki Yushi、Yamaguchi Tomokazu、Sato Yusuke、Wakita Akiyuki、Minamiya Yoshihiro、Kuba Keiji
    • Journal Title

      Genes to Cells

      Volume: 28 Issue: 8 Pages: 573-584

    • DOI

      10.1111/gtc.13051

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-23K06146, KAKENHI-PROJECT-22K19551
  • [Journal Article] Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer2022

    • Author(s)
      Fujita Hiromu、Motoyama Satoru、An Jianbo、Nagakai Yushi、Yamaguchi Tomokazu、Koyota Souichi、Sato Yusuke、Wakita Akiyuki、Imai Kazuhiro、Kuba Keiji、Minamiya Yoshihiro
    • Journal Title

      Surgery

      Volume: S0039-6060 Issue: 6 Pages: 1170-1170

    • DOI

      10.1016/j.surg.2021.11.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-20K07285
  • [Journal Article] Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression2022

    • Author(s)
      An Jianbo、Nagaki Yushi、Motoyama Satoru、Kuze Yuta、Hoshizaki Midori、Kemuriyama Kohei、Yamaguchi Tomokazu、Ebihara Takashi、Minamiya Yoshihiro、Suzuki Yutaka、Imai Yumiko、Kuba Keiji
    • Journal Title

      Oncogene

      Volume: 41 Issue: 50 Pages: 5319-5330

    • DOI

      10.1038/s41388-022-02525-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-21K19368, KAKENHI-PROJECT-22K19551, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-20K09048, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-21H02707
  • [Journal Article] ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury2021

    • Author(s)
      Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, An J, Saku A, Nukiwa R, Utsumi D, Kiso M, Yasuhara A, Poon VK, Chan CC, Fujino Y, Motoyama S, Nagata S, Penninger JM, Kamada H, Yuen KY, Kamitani W, Maeda K, Kawaoka Y, Yasutomi Y, Imai Y, Kuba Keiji
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 6791-6791

    • DOI

      10.1038/s41467-021-27097-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20K16153, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-21K19395, KAKENHI-PROJECT-17H06179
  • [Journal Article] MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages2019

    • Author(s)
      An J, Naruse K T, Hinohara K, Soejima Y, Sawabe M, Nakagawa Y, Kuwahara K, Kimura A.
    • Journal Title

      Journal of Molecular and cellular cardiology

      Volume: 133 Pages: 26-35

    • DOI

      10.1016/j.yjmcc.2019.05.015

    • NAID

      130007811832

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08580, KAKENHI-PROJECT-17H04174, KAKENHI-PROJECT-17K08718, KAKENHI-PROJECT-18K15060
  • [Patent] Galectin-7阻害剤を用いた癌転移抑制剤2022

    • Inventor(s)
      久場敬司、本山悟、安健博、鈴木穣
    • Industrial Property Rights Holder
      秋田大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-22K06907
  • [Presentation] 扁平上皮癌の不均一性における免疫抑制の微小環境は高転移性細胞の発生をもたらす2023

    • Author(s)
      長岐雄志、安健博、本山悟、山口智和、星崎みどり、煙山紘平、鈴木穣、今井由美子、南谷佳弘、久場敬司
    • Organizer
      第32回日本がん転移学会学術集会・総会
    • Data Source
      KAKENHI-PROJECT-22K06907
  • [Presentation] Upregulation of Galectin-7 in specific tumor microenvironment contributes to squamous cell carcinoma metastasis2022

    • Author(s)
      Jianbo An,Yushi Nagaki,Midori Hoshizaki,Tomokazu Yamaguchi,Yuta Kuze,Yumiko Imai,Satoru Motoyama,Yutaka Suzuki,Keiji Kuba
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-22K06907
  • [Presentation] 扁平上皮癌に由来する新たな転移誘導因子Galectin-7の同定2022

    • Author(s)
      安健博、長岐雄志、星崎みどり、山口智和、久世裕太、今井由美子、本山悟、鈴木穣、久場敬司
    • Organizer
      第95回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-22K06907
  • [Presentation] Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma2022

    • Author(s)
      Jianbo An,Yushi Nagaki,Midori Hoshizaki,Tomokazu Yamaguchi,Yuta Kuze,Yumiko Imai,Satoru Motoyama,Yutaka Suzuki,Keiji Kuba
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K06907
  • [Presentation] マクロファージを介したCCR4-NOTの動脈硬化進行への影響2021

    • Author(s)
      安健博,山口智和,星崎みどり,久場敬司
    • Organizer
      第31回日本循環薬理学会
    • Data Source
      KAKENHI-PROJECT-20K16153
  • [Presentation] 動脈硬化形成におけるCCR4-NOT の役割及び制御機構の解析2021

    • Author(s)
      安健博,山口智和,星崎みどり,久場敬司
    • Organizer
      第87回日本生化学会東北支部例会
    • Data Source
      KAKENHI-PROJECT-20K16153
  • [Presentation] MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages2020

    • Author(s)
      Jianbo An, Taeko Naruse, Kunihiko Hinohara, Yurie Soejima, Motoji Sawabe, Yasuaki Nakagawa, Koichiro Kuwahara, Keiji Kuba, Akinori Kimura
    • Organizer
      第93回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-18K15060
  • [Presentation] MRTF-Aはマクロファージ機能を制御して動脈硬化形成に関わる2019

    • Author(s)
      安 健博、成瀬 妙子、日野原 邦彦、副島 友莉恵、沢辺 元司、中川 靖章、桑原 宏一郎、久場 敬司、木村 彰方
    • Organizer
      第29回日本循環薬理学会
    • Data Source
      KAKENHI-PROJECT-18K15060
  • [Presentation] MKL1 Affects Proliferation/Survival Property of Pro-Atherogenic Macrophages2018

    • Author(s)
      Jianbo An, Taeko K Naruse, Akinori Kimura
    • Organizer
      Vascular Discovery: From Genes to Medicine 2018 Scientific Session (ATVB/PVD 2018)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15060
  • 1.  久場 敬司 (10451915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  NAKAGAWA Yasuaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  錦見 俊雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  桑原 宏一郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  今井 由美子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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