AN JIANBO 安健博

… Alternative Names

An Jianbo 安健博

Less

Researcher Number	40723771
Other IDs
Affiliation (Current)	2025: 秋田大学, 医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 秋田大学, 医学系研究科, 助教 2019 – 2023: 秋田大学, 医学系研究科, 助教 2018: 東京医科歯科大学, 難治疾患研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Basic Section 43050:Genome biology-related
Keywords	Principal Investigator 動脈硬化 / マクロファージ / 動脈硬化症 / 空間的トランスクリプトーム解析 / Galectin-7 / 免疫抑制 / がん微小環境 / 転移 / MDSCs / G-CSF … More / 扁平上皮癌 / 炎症 / 炎症応答 / Interferon / CCR4-NOT / 脂肪萎縮症 / MRTF-A / 細胞増殖 / MKL1 … More Except Principal Investigator 脂肪細胞分化 / クエン酸回路 / 糖代謝 / ヒストン脱メチル化 / エピゲノム Less

Elucidation of the regulatory mechanism of energy metabolism by the metabolism-epigenome axis
- Principal Investigator
  
  松村欣宏
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Akita University
癌の転移・再発における細胞外Galectin-Xを介した免疫抑制機構の解明Principal Investigator
- Principal Investigator
  
  安健博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Akita University
The role of CCR4-NOT in the development of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  An Jianbo
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Akita University
The role of macrophagic MKL1 in the pathogenesis of atherosclerosisPrincipal Investigator
- Principal Investigator
  
  An Jianbo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Akita University
  Tokyo Medical and Dental University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Patent

[Journal Article] Squamous cell carcinoma‐derived <scp>G‐CSF</scp> promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation, associated with poor prognosis of the patients2023
- Author(s)
  Kemuriyama Kohei、An Jianbo、Motoyama Satoru、Nagaki Yushi、Yamaguchi Tomokazu、Sato Yusuke、Wakita Akiyuki、Minamiya Yoshihiro、Kuba Keiji
- Journal Title
  
  Genes to Cells
  
  Volume: 28 Issue: 8 Pages: 573-584
- DOI
  10.1111/gtc.13051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-23K06146, KAKENHI-PROJECT-22K19551
[Journal Article] Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer2022
- Author(s)
  Fujita Hiromu、Motoyama Satoru、An Jianbo、Nagakai Yushi、Yamaguchi Tomokazu、Koyota Souichi、Sato Yusuke、Wakita Akiyuki、Imai Kazuhiro、Kuba Keiji、Minamiya Yoshihiro
- Journal Title
  
  Surgery
  
  Volume: S0039-6060 Issue: 6 Pages: 1170-1170
- DOI
  10.1016/j.surg.2021.11.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-20K07285
[Journal Article] Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression2022
- Author(s)
  An Jianbo、Nagaki Yushi、Motoyama Satoru、Kuze Yuta、Hoshizaki Midori、Kemuriyama Kohei、Yamaguchi Tomokazu、Ebihara Takashi、Minamiya Yoshihiro、Suzuki Yutaka、Imai Yumiko、Kuba Keiji
- Journal Title
  
  Oncogene
  
  Volume: 41 Issue: 50 Pages: 5319-5330
- DOI
  10.1038/s41388-022-02525-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06907, KAKENHI-PROJECT-21K19368, KAKENHI-PROJECT-22K19551, KAKENHI-PROJECT-22H04925, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-20K09048, KAKENHI-PROJECT-17H06179, KAKENHI-PROJECT-21H02707
[Journal Article] ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury2021
- Author(s)
  Yamaguchi T, Hoshizaki M, Minato T, Nirasawa S, Asaka MN, Niiyama M, Imai M, Uda A, Chan JF, Takahashi S, An J, Saku A, Nukiwa R, Utsumi D, Kiso M, Yasuhara A, Poon VK, Chan CC, Fujino Y, Motoyama S, Nagata S, Penninger JM, Kamada H, Yuen KY, Kamitani W, Maeda K, Kawaoka Y, Yasutomi Y, Imai Y, Kuba Keiji
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 6791-6791
- DOI
  10.1038/s41467-021-27097-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21566, KAKENHI-PROJECT-20K16153, KAKENHI-PROJECT-20H03426, KAKENHI-PROJECT-20K07285, KAKENHI-PROJECT-21K19395, KAKENHI-PROJECT-17H06179
[Journal Article] MRTF-A regulates proliferation and survival properties of pro-atherogenic　macrophages2019
- Author(s)
  An J, Naruse K T, Hinohara K, Soejima Y, Sawabe M,　Nakagawa Y, Kuwahara K, Kimura A.
- Journal Title
  
  Journal of Molecular and cellular cardiology
  
  Volume: 133 Pages: 26-35
- DOI
  10.1016/j.yjmcc.2019.05.015
- NAID
  130007811832
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08580, KAKENHI-PROJECT-17H04174, KAKENHI-PROJECT-17K08718, KAKENHI-PROJECT-18K15060
[Patent] Galectin-7阻害剤を用いた癌転移抑制剤2022
- Inventor(s)
  久場敬司、本山悟、安健博、鈴木穣
- Industrial Property Rights Holder
  秋田大学
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] 扁平上皮癌の不均一性における免疫抑制の微小環境は高転移性細胞の発生をもたらす2023
- Author(s)
  長岐雄志、安健博、本山悟、山口智和、星崎みどり、煙山紘平、鈴木穣、今井由美子、南谷佳弘、久場敬司
- Organizer
  第32回日本がん転移学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] Upregulation of Galectin-7 in specific tumor microenvironment contributes to squamous cell carcinoma metastasis2022
- Author(s)
  Jianbo An，Yushi Nagaki，Midori Hoshizaki，Tomokazu Yamaguchi，Yuta Kuze，Yumiko Imai，Satoru Motoyama，Yutaka Suzuki，Keiji Kuba
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] 扁平上皮癌に由来する新たな転移誘導因子Galectin-7の同定2022
- Author(s)
  安健博、長岐雄志、星崎みどり、山口智和、久世裕太、今井由美子、本山悟、鈴木穣、久場敬司
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma2022
- Author(s)
  Jianbo An，Yushi Nagaki，Midori Hoshizaki，Tomokazu Yamaguchi，Yuta Kuze，Yumiko Imai，Satoru Motoyama，Yutaka Suzuki，Keiji Kuba
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K06907
[Presentation] マクロファージを介したCCR4-NOTの動脈硬化進行への影響2021
- Author(s)
  安健博，山口智和，星崎みどり，久場敬司
- Organizer
  第31回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-20K16153
[Presentation] 動脈硬化形成におけるCCR4-NOT の役割及び制御機構の解析2021
- Author(s)
  安健博，山口智和，星崎みどり，久場敬司
- Organizer
  第87回日本生化学会東北支部例会
- Data Source
  KAKENHI-PROJECT-20K16153
[Presentation] MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages2020
- Author(s)
  Jianbo An, Taeko Naruse, Kunihiko Hinohara, Yurie Soejima, Motoji Sawabe, Yasuaki Nakagawa, Koichiro Kuwahara, Keiji Kuba, Akinori Kimura
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K15060
[Presentation] MRTF-Aはマクロファージ機能を制御して動脈硬化形成に関わる2019
- Author(s)
  安　健博、成瀬　妙子、日野原　邦彦、副島　友莉恵、沢辺　元司、中川　靖章、桑原　宏一郎、久場　敬司、木村　彰方
- Organizer
  第29回日本循環薬理学会
- Data Source
  KAKENHI-PROJECT-18K15060
[Presentation] MKL1 Affects Proliferation/Survival Property of Pro-Atherogenic Macrophages2018
- Author(s)
  Jianbo An, Taeko K Naruse, Akinori Kimura
- Organizer
  Vascular Discovery: From Genes to Medicine 2018 Scientific Session (ATVB/PVD 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15060

1. 久場敬司 (10451915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
2. 松村欣宏 (20375257)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 荒井誠 (10865059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 小泉幸央 (80353465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NAKAGAWA Yasuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 錦見俊雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 桑原宏一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 今井由美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AN JIANBO 安 健博

An Jianbo 安 健博

Research Projects

Research Products

Co-Researchers

Elucidation of the regulatory mechanism of energy metabolism by the metabolism-epigenome axis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

癌の転移・再発における細胞外Galectin-Xを介した免疫抑制機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of CCR4-NOT in the development of atherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of macrophagic MKL1 in the pathogenesis of atherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Squamous cell carcinoma‐derived <scp>G‐CSF</scp> promotes tumor growth and metastasis in mice through neutrophil recruitment and tumor cell proliferation, associated with poor prognosis of the patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Peritumoral CD16b positive-neutrophil accumulation strongly correlates with regional lymph node metastasis in thoracic esophageal squamous cell cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of Galectin-7 as a crucial metastatic enhancer of squamous cell carcinoma associated with immunosuppression2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MRTF-A regulates proliferation and survival properties of pro-atherogenic macrophages2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Patent] Galectin-7阻害剤を用いた癌転移抑制剤2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] 扁平上皮癌の不均一性における免疫抑制の微小環境は高転移性細胞の発生をもたらす2023

Author(s)

Organizer

Data Source

[Presentation] Upregulation of Galectin-7 in specific tumor microenvironment contributes to squamous cell carcinoma metastasis2022

Author(s)

Organizer

Data Source

[Presentation] 扁平上皮癌に由来する新たな転移誘導因子Galectin-7の同定2022

Author(s)

Organizer

Data Source

[Presentation] Immunosuppression-elicited Galectin-7 is a crucial metastatic enhancer of squamous cell carcinoma2022

Author(s)

Organizer

Data Source

[Presentation] マクロファージを介したCCR4-NOTの動脈硬化進行への影響2021

Author(s)

Organizer

AN JIANBO 安健博

An Jianbo 安健博

[Journal Article] MRTF-A regulates proliferation and survival properties of pro-atherogenic　macrophages2019