Shimomura Kazunori 下村和範

Researcher Number	40755998
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 招へい教授 2025: 関西福祉科学大学, 保健医療学部, 教授
Affiliation (based on the past Project Information) *help	2024: 関西福祉科学大学, 保健医療学部, 教授 2023: 大阪大学, 大学院医学系研究科, 招へい教授 2022 – 2023: 大阪大学, 大学院医学系研究科, 招へい教員 2020 – 2021: 大阪大学, 医学系研究科, 招へい教員 2019: 大阪大学, 医学系研究科, 助教 2016 – 2018: 大阪大学, 医学系研究科, 特任助教(常勤) 2015: 大阪大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery Except Principal Investigator Basic Section 56020:Orthopedics-related / Basic Section 59020:Sports sciences-related / Medium-sized Section 90:Biomedical engineering and related fields
Keywords	Principal Investigator 整形外科 / エレクトロスピニング法 / 半月板損傷 / 間葉系幹細胞 / スキャフォールド / 半月板 / 再生医療 / ナノファイバー / ナノファイバースキャフォールド / エクソソーム … More / 細胞外小胞 / 半月板再生 / 関節モデル / 骨 / 軟骨 / 血管網 / 生態内類似構造 / 生体内類似構造 / 変形性関節症 / 骨再生 / 軟骨再生 / 血管構造 / 骨軟骨組織 / 三次元組織 / 骨軟骨再生 / 膝関節 / 家兎 / ミニブタ / エレクトロスピニング … More Except Principal Investigator 変形性関節症 / 運動パフォーマンス / 超音波画像診断装置 / 組織弾性 / 膝蓋腱 / ジャンパー膝 / バイオプリント / 組織工学 / 運動器 / 複合組織 / 異種界面 / コラーゲン / 繰り返し圧縮刺激 / 関節症 / マトリックスメタロプロテアーゼ / インテグリン / 疼痛関連因子 / 基質分解 / 炎症 / メカニカルストレス・力学刺激 / 網羅的遺伝子発現解析 / 力学刺激 / 網羅的遺伝子解析 / 組織変性 / 炎症性サイトカイン / メカニカルストレス（力学刺激） / エクソソーム / 間葉系幹細胞 / 再生医療 Less

膝蓋腱の力学特性と運動パフォーマンスとの関係からみたジャンパー膝の発生要因の解明
- Principal Investigator
  
  三谷保弘
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  Kansai University of Welfare Sciences
細胞外小胞を徐放するナノファイバースキャフォールドを用いた新規半月板治療法の開発Principal Investigator
- Principal Investigator
  
  下村和範
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
Scientific understanding of heterogeneous interface joining of multiple tissues and ex vivo construction of locomotor models
- Principal Investigator
  
  Matsusaki Michiya
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Osaka University
Development of in vivo-like 3D vascularized osteochondral tissuePrincipal Investigator
- Principal Investigator
  
  Shimomura Kazunori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
Development of a safe and efficient methods for the collection of mesenchymal stem cell-derived extracellular vesichles for the treatment of osteoarthritis
- Principal Investigator
  
  Nakamura Norimasa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
Investigation of the pathophysiology of knee osteoarthritis with an emphasis on PGE2 / NGF / MMP production mechanism by mechanical stimulation
- Principal Investigator
  
  Nakata Ken
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Osaka University
Repairing incurable meniscal tears using a novel nanofibrous scaffoldPrincipal Investigator
- Principal Investigator
  
  Shimomura Kazunori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University
線維の配向性を付与したスキャフォールドを用いた半月板横断裂に対する治療法の確立Principal Investigator
- Principal Investigator
  
  下村和範
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Osaka University

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] Failed Cartilage Surgery (Chapter 8). Orthopaedic Sports Medicine - An Encyclopedic Review of Diagnosis, Prevention, and Management -.2023
- Author(s)
  Jacob G, Shimomura K, Nakamura N
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-23K08676
[Book] 特集「疲労骨折を克服する, 予防から最新の保存療法戦略まで」　疲労骨折に対するBiologics治療. 臨床スポーツ医学.2023
- Author(s)
  下村和範, 中村憲正.
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-23K08676
[Book] 特集「変形性関節症：病態研究と治療の最前線」　滑膜間葉系幹細胞を用いた膝関節軟骨再生. Precision Medicine.2023
- Author(s)
  下村和範, 中村憲正
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-23K08676
[Book] ISAKOS/ICRS Book “Orthobiologics: Injectable Therapies for the Musculoskeletal System” Chapter 25: Cartilage Lesions and Osteoarthritis: Cell Therapy.2021
- Author(s)
  Fernandes TL, Shimomura K, Hart DA, Boffa A, Nakamura N
- Total Pages
  14
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS Book “Advances in Knee Ligament and Knee Preservation Surgery” Chapter 37: Current Introduction of the Biological Agent Derived from Adipose Tissue to the Treatment of Knee Osteoarthritis.2021
- Author(s)
  Ando W, Wolfe I, Shimomura K, Lyman S, Yokota N, Nakamura N
- Total Pages
  14
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS/ICRS Book “Early Osteoarthritis” Chapter 15: The Current Role of Stem Cell Therapy and iPS Cells.2021
- Author(s)
  Jacob G, Shimomura K, Hart DA, Nakamura N.
- Total Pages
  13
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] 膝関節鏡視下手術 (ビジュアル・サージカルテクニック) Chapter 4　診断：正常膝関節の鏡視所見2021
- Author(s)
  下村和範、中村憲正
- Total Pages
  5
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS/ICRS Book “Cartilage Injury of the Knee” Chapter 20: Role of MSCs in Symptomatic Cartilage Defects2021
- Author(s)
  Jacob G, Shimomura K, Nakamura N
- Total Pages
  9
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS Book “Orthopaedic Biomechanics in Sports Medicine” Chapter 5:Mechanical and Biologic Properties of Articular Cartilage Repair Biomaterials.2021
- Author(s)
  Jacob G, Shimomura K, Hart DA, Fujie H, Nakamura N
- Total Pages
  15
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS Book “Orthopaedic Biomechanics in Sports Medicine” Chapter 33:Biomechanics of Cartilage Repair.2021
- Author(s)
  Iseki T, Rothrauff BB, Shimomura K, Nakamura N
- Total Pages
  8
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS Book “Advances in Knee Ligament and Knee Preservation Surgery” Chapter 35: Clinical Application of Scaffold-Free Tissue-Engineered Construct Derived from Synovial Stem Cells.2021
- Author(s)
  Shimomura K, Hart DA, Ando W, Nakamura N
- Total Pages
  9
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS Book “Joint Function Preservation” Chapter 20: Biphasic Osteochondral Restoration Techniques Using Synovial Stem Cells and Artificial Bone.2021
- Author(s)
  Jacob G, Shimomura K, Ando W, Hart DA, Nakamura N
- Total Pages
  7
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS/ICRS Book “Orthobiologics: Injectable Therapies for the Musculoskeletal System” Chapter 22: Meniscal Lesions: Cell Therapy.2021
- Author(s)
  Shimomura K, Hart DA, Nakamura N
- Total Pages
  12
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Book] ISAKOS/ICRS Book “Early Osteoarthritis” Chapter 19: Meniscus Injury and Early Osteoarthritis.2021
- Author(s)
  Jacob G, Shimomura K, Hart DA, Nakamura N
- Total Pages
  11
- Publisher
  Springer
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Small extracellular vesicles derived from human adipose‐derived mesenchymal stromal cells cultured in a new chemically‐defined contaminate‐free media exhibit enhanced biological and therapeutic effects on human chondrocytes in vitro and in a mouse osteoarthritis model2023
- Author(s)
  Hanai Hiroto、Hart David A.、Jacob George、Shimomura Kazunori、Ando Wataru、Yoshioka Yusuke、Ochiya Takahiro、Nakagawa Shinicihi、Nakamura Masato、Okada Seiji、Nakamura Norimasa
- Journal Title
  
  Journal of Extracellular Vesicles
  
  Volume: 12 Issue: 7
- DOI
  10.1002/jev2.12337
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K15688, KAKENHI-PROJECT-23K08676, KAKENHI-PROJECT-22K20937, KAKENHI-PROJECT-23K24460
[Journal Article] Five-Year Outcomes After Implantation of a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stromal Cells for Repair of Knee Chondral Lesions.2023
- Author(s)
  Shimomura K, Ando W, Hart DA, Yonetani Y, Horibe S, Nakamura N.
- Journal Title
  
  Orthop J Sports Med
  
  Volume: 11 Issue: 8
- DOI
  10.1177/23259671231189474
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08676
[Journal Article] 解剖学的長方形骨孔前十字靱帯再建術における移植腱の違いによる成績比較－骨付き膝蓋腱vs骨付き大腿四頭筋腱－2023
- Author(s)
  下村和範　米谷泰一　田中綾香　辻井聡　濱田雅之
- Journal Title
  
  JOSKAS
  
  Volume: -
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Freeze Dried Noncoagulating Platelet-Derived Factor Concentrate is a Safe and Effective Treatment for Early Knee Osteoarthritis.2023
- Author(s)
  Ohtsuru T, Otsuji M, Nakanishi J, Lyman S, Hanai H, Shimomura K, Ando W, Nakamura N.
- Journal Title
  
  Knee Surg Sports Traumatol Arthrosc.
  
  Volume: -
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Freeze Dried Noncoagulating Platelet-Derived Factor Concentrate is a Safe and Effective Treatment for Early Knee Osteoarthritis.2023
- Author(s)
  Ohtsuru T, Otsuji M, Nakanishi J, Lyman S, Hanai H, Shimomura K, Ando W, Nakamura N.
- Journal Title
  
  Knee Surg Sports Traumatol Arthrosc
  
  Volume: 31 Issue: 11 Pages: 4716-4723
- DOI
  10.1007/s00167-023-07414-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08676
[Journal Article] Repair of osteochondral defects: efficacy of a tissue-engineered hybrid implant containing both human MSC and human iPSC-cartilaginous particles2023
- Author(s)
  Nakagawa Shinichi、Ando Wataru、Shimomura Kazunori、Hart David A.、Hanai Hiroto、Jacob George、Chijimatsu Ryota、Yarimitu Seido、Fujie Hiromichi、Okada Seiji、Tsumaki Noriyuki、Nakamura Norimasa
- Journal Title
  
  npj Regenerative Medicine
  
  Volume: 8 Issue: 1 Pages: 59-59
- DOI
  10.1038/s41536-023-00335-x
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08773, KAKENHI-PROJECT-23K07813, KAKENHI-PROJECT-23K08676, KAKENHI-PROJECT-23K27720
[Journal Article] Utilization of Orthobiologic Augmentation for Meniscal Repairs: Current Concepts and Future Perspectives.2023
- Author(s)
  Shimomura K, Jacob G, Hanai H, Nakamura. N
- Journal Title
  
  Journal of Cartilage & Joint Preservation.
  
  Volume: - Issue: 2 Pages: 100090-100090
- DOI
  10.1016/j.jcjp.2022.100090
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504, KAKENHI-PROJECT-23K08676
[Journal Article] Five-year outcomes following implantation of a scaffold-free tissue-engineered construct generated from autologous synovial mesenchymal stromal cells for repair of knee chondral lesions.2023
- Author(s)
  Shimomura K, Ando W, Hart DA, Yonetani Y, Horibe S, Nakamura N.
- Journal Title
  
  Orthop J Sports Med.
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Clinical Safety and Effectiveness of Adipose-Derived Stromal Cell vs Stromal Vascular Fraction Injection for Treatment of Knee Osteoarthritis: 2-Year Results of Parallel Single-Arm Trials2022
- Author(s)
  Yokota Naomasa、Lyman Stephen、Hanai Hiroto、Shimomura Kazunori、Ando Wataru、Nakamura Norimasa
- Journal Title
  
  The American Journal of Sports Medicine
  
  Volume: 50 Issue: 10 Pages: 2659-2668
- DOI
  10.1177/03635465221107364
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20937, KAKENHI-PROJECT-20K09504, KAKENHI-PROJECT-23K24460
[Journal Article] Editorial: Tissue Engineering and Cell Therapy for Cartilage Restoration.2022
- Author(s)
  Fernandes TL, Bueno DF, Shimomura K, Shao Z, Gomoll AH.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 10 Pages: 947588-947588
- DOI
  10.3389/fcell.2022.947588
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504, KAKENHI-PROJECT-23K24460
[Journal Article] Two uncommon complications related to suture knots after meniscal all-inside suture repair: A case report.2022
- Author(s)
  Tanaka A, Tsujii A, Shimomura K, Yonetani Y, Hamada M.
- Journal Title
  
  JBJS Case Connect.
  
  Volume: 12 Issue: 3
- DOI
  10.2106/jbjs.cc.22.00014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Histological Analysis of Cartilage Defects Repaired with an Autologous Human Stem-cell Construct 48 Weeks Post-Implantation Reveals Structural Details not Detected by T2 Mapping MRI.2021
- Author(s)
  Shimomura K, Hamada H, Hart DA, Ando W, Nishii T, Trattnig S, Nehrer S, Nakamura N.
- Journal Title
  
  Cartilage
  
  Volume: in press Issue: 1_suppl Pages: 694S-706S
- DOI
  10.1177/1947603521989423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Tissue Wrapping Augmentation for Anterior Cruciate Ligament Reconstruction: A Review of Clinical Literature.2021
- Author(s)
  Jacob G, Shimomura K, Yogesh K, Nakamura N
- Journal Title
  
  Biologic Orthopedics Journal.
  
  Volume: in press Issue: SP2 Pages: e1-e6
- DOI
  10.22374/boj.v3isp2.31
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Posterior Ankle Impingement Caused by Hyaline-like Cartilage Generation in Ballet Dancers -A Report of 2 Cases.2021
- Author(s)
  Kinugasa K, Shimomura K, Tachibana Y, Hiramatsu K, Horibe S, Shino K, Tanaka Y
- Journal Title
  
  J Foot Ankle Surg
  
  Volume: in press Issue: 4 Pages: e9-e14
- DOI
  10.1053/j.jfas.2021.10.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504
[Journal Article] Potential of soluble decellularized extracellular matrix for musculoskeletal tissue engineering - comparison of various mesenchymal tissues -2020
- Author(s)
  Hanai H, Jacob G, Nakagawa S, Tuan RS, Nakamura N, Shimomura K
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 8 Pages: 581972-581972
- DOI
  10.3389/fcell.2020.581972
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504, KAKENHI-PROJECT-19H03781
[Journal Article] Enhancement of chondrogenic differentiation supplemented by a novel small compound for chondrocyte-based tissue engineering2020
- Author(s)
  Hamamoto Shuichi、Chijimatsu Ryota、Shimomura Kazunori、Kobayashi Masato、Jacob George、Yano Fumiko、Saito Taku、Chung Ung-il、Tanaka Sakae、Nakamura Norimasa
- Journal Title
  
  Journal of Experimental Orthopaedics
  
  Volume: 7 Issue: 1 Pages: 446-458
- DOI
  10.1186/s40634-020-00228-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09568, KAKENHI-PROJECT-16H06264, KAKENHI-PROJECT-17K10956, KAKENHI-PROJECT-17K10998, KAKENHI-PROJECT-20K09452, KAKENHI-PROJECT-20K09473, KAKENHI-PROJECT-20K18053, KAKENHI-PROJECT-18K09055, KAKENHI-PROJECT-19K09641, KAKENHI-PROJECT-17K10955, KAKENHI-PROJECT-17K10997, KAKENHI-PROJECT-20K09405
[Journal Article] Osteochondral Injury, Management and Tissue Engineering Approaches.2020
- Author(s)
  Jacob G, Shimomura K, Nakamura N.
- Journal Title
  
  Front Cell Dev Biol.
  
  Volume: 8 Pages: 580868-580868
- DOI
  10.3389/fcell.2020.580868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504, KAKENHI-PROJECT-19H03781
[Journal Article] Enhanced repair of meniscal hoop structure injuries using an aligned electrospun nanofibrous scaffold combined with a mesenchymal stem cell-derived tissue engineered construct2019
- Author(s)
  Shimomura Kazunori、Rothrauff Benjamin B.、Hart David A.、Hamamoto Shuichi、Kobayashi Masato、Yoshikawa Hideki、Tuan Rocky S.、Nakamura Norimasa
- Journal Title
  
  Biomaterials
  
  Volume: 192 Pages: 346-354
- DOI
  10.1016/j.biomaterials.2018.11.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04958, KAKENHI-PROJECT-16H06264
[Journal Article] The Meniscus Tear: A Review of Stem Cell Therapies2019
- Author(s)
  Jacob G, Shimomura K, Krych AJ, Nakamura N
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 1 Pages: 92-92
- DOI
  10.3390/cells9010092
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06264
[Journal Article] Establishing a new meniscus treatment with nano-level fibrous orientation scaffolds, the Japan Society for the Promotion of Science (interview article)2018
- Author(s)
  Shimomura K
- Journal Title
  
  Impact
  
  Volume: 2018 Issue: 2 Pages: 50-52
- DOI
  10.21820/23987073.2018.2.50
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06264
[Journal Article] Scaffold-free tissue engineering for injured joint surface restoration2018
- Author(s)
  Shimomura Kazunori、Ando Wataru、Fujie Hiromichi、Hart David A.、Yoshikawa Hideki、Nakamura Norimasa
- Journal Title
  
  Journal of Experimental Orthopaedics
  
  Volume: 5 Issue: 1 Pages: 1-14
- DOI
  10.1186/s40634-017-0118-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04958, KAKENHI-PROJECT-16H06264
[Journal Article] Meniscal repair and regeneration: Current strategies and future perspectives2018
- Author(s)
  Shimomura Kazunori、Hamamoto Shuichi、Hart David A.、Yoshikawa Hideki、Nakamura Norimasa
- Journal Title
  
  Journal of Clinical Orthopaedics and Trauma
  
  Volume: 9 Issue: 3 Pages: 247-253
- DOI
  10.1016/j.jcot.2018.07.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04958, KAKENHI-PROJECT-16H06264
[Presentation] Comparison of three different forms of commercially available hydroxyapatite artificial bone for a hybrid implant with a tissue-engineered construct derived from synovial mesenchymal stem cells for osteochondral repair.2024
- Author(s)
  Shimomura K, Yarimitsu S, Jacob G, Hart DA, Fujie H, Nakamura N.
- Organizer
  Orthopaedic Research Society 2024 Annual Meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08676
[Presentation] MSC-based strategy. (Symposium “The Osteochondral Unit: Subchondral Bone Cartilage and Joints”).2023
- Author(s)
  Shimomura K, Fujie H, Nakamura N.
- Organizer
  14th Biennial International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) Congress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08676
[Presentation] Five-year outcomes following implantation of a scaffold-free tissue-engineered construct generated from autologous synovial mesenchymal stem cells for repair of knee chondral lesions.2023
- Author(s)
  Shimomura K, Ando W, Hart DA, Yonetani Y, Horibe S, Nakamura N.
- Organizer
  14th Biennial International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08676
[Presentation] 滑膜間葉系幹細胞由来三次元人工組織・ハイドロキシアパタイト人工骨複合体を用いた骨軟骨再生 -人工骨の形状の違いによる修復能の検討-2023
- Author(s)
  下村和範、藤江裕道、中村憲正
- Organizer
  日本膝関節学会
- Data Source
  KAKENHI-PROJECT-23K08676
[Presentation] 同種滑膜間葉系幹細胞由来三次元人工組織を用いた第III相膝関節軟骨再生臨床試験2023
- Author(s)
  下村和範、渡辺淳也、鈴木智之、中川晃一、岩崎潤一、中島歩、松本昌也、瀬川耕太郎、辻井聡、中村憲正
- Organizer
  日本膝関節学会
- Data Source
  KAKENHI-PROJECT-23K08676
[Presentation] Comparison of clinical outcomes between a bone-patellar tendon-bone and quadriceps tendon-bone autografts in anatomic rectangular tunnel anterior cruciate ligament reconstruction.2023
- Author(s)
  Shimomura K, Yonetani Y, Tanaka A, Tsujii A, Hamada M.
- Organizer
  14th Biennial International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K08676
[Presentation] ナノレベル線維構造を有するスキャフォールドを用いた新たな半月板治療法の確立- 変形性関節症の予防を目指して -2022
- Author(s)
  下村和範
- Organizer
  第21回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] 滑膜間葉系幹細胞を用いた軟骨再生（シンポジウム：半月板・軟骨再生のバイオメカニクス）2022
- Author(s)
  下村和範、中村憲正
- Organizer
  第49回日本臨床バイオメカニクス学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] Five-year Outcome of a Scaffold-free Mesenchymal Stem Cell-based Tissue-engineered Construct for Repair of Knee Chondral Lesion.2022
- Author(s)
  Shimomura K, Ando W, Hart DA, Yonetani Y, Horibe S, Nakamura N.
- Organizer
  The 16th World Congress of the International Cartilage Repair and Joint Preservation Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] 軟骨再生の現状と将来展望（シンポジウム：新時代の膝温存治療を考える）2022
- Author(s)
  下村和範、中村憲正
- Organizer
  第139回中部日本整形外科災害外科学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] スキャフォールドフリー滑膜間葉系幹細胞由来三次元人工組織を用いた軟骨再生（シンポジウム：スポーツ損傷に対するバイオセラピー・再生医療）2022
- Author(s)
  下村和範、中村憲正
- Organizer
  第33回日本臨床スポーツ医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] Comparison of clinical outcomes after anatomic rectangular tunnel anterior cruciate ligament reconstruction with an autograft between bone-patellar tendon-bone and quadriceps tendon.2022
- Author(s)
  Shimomura K, Yonetani Y, Tanaka A, Tsujii A, Hamada M.
- Organizer
  JOSKAS-JOSSM 2022
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] 解剖学的長方形骨孔前十字靱帯再建術における移植腱の違いによる臨床成績の比較 -骨付き大腿四頭筋腱 vs 骨付き膝蓋腱-2022
- Author(s)
  下村和範、辻井聡、米谷泰一
- Organizer
  第33回日本臨床スポーツ医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] Enhanced Repair of Meniscal Hoop Structure Injuries Using An Aligned Electrospun Nanofibrous Scaffold Combined with a Mesenchymal Stem Cell-derived Tissue Engineered Construct2021
- Author(s)
  Kazunori Shimomura, Benjamin B. Rothrauff, David A. Hart, Shuichi Hamamoto, Masato Kobayashi, Hideki Yoshikawa, Rocky S. Tuan, Norimasa Nakamura
- Organizer
  第26回日本軟骨代謝学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] Cartilage Regeneration by a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stem Cells（シンポジウム）2021
- Author(s)
  Kazunori Shimomura, Norimasa Nakamura
- Organizer
  第36回日本整形外科学会基礎学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] Cartilage Regeneration by a Scaffold-Free Tissue-Engineered Construct Generated From Autologous Synovial Mesenchymal Stem Cells.2020
- Author(s)
  Shimomura K, Ando W, Nakamura N.
- Organizer
  JOSKAS-JOSSM 2020
- Invited
- Data Source
  KAKENHI-PROJECT-20K09504
[Presentation] A novel approach to the treatment of meniscal hoop injuries using a mesenchymal stem cell-seeded electrospun nanofibrous scaffold.2019
- Author(s)
  Shimomura K, Rothrauff BB, Hart DA, Hamamoto S, Kobayashi M, Yoshikawa H, Tuan RS, Nakamura N
- Organizer
  International Cartilage Repair and Joint Preservation Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06264
[Presentation] Enhanced Repair of Meniscal Hoop Structure Injuries Using An Aligned Electrospun Nanofibrous Scaffold Combined with a Mesenchymal Stem Cell-derived Tissue Engineered Construct2019
- Author(s)
  Kazunori Shimomura, Benjamin B. Rothrauff, David A. Hart, Shuichi Hamamoto, Masato Kobayashi, Hideki Yoshikawa, Rocky S. Tuan, Norimasa Nakamura
- Organizer
  Orthopaedic Research Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06264
[Presentation] Regenerative Medicine Approaches for the Treatment of Incurable Meniscal Injuries.2019
- Author(s)
  Shimomura K, Yoshikawa H, Nakamura N
- Organizer
  Japanese Orthopaedic Society of Knee, Arthroscopy and Sports Medicine
- Invited
- Data Source
  KAKENHI-PROJECT-16H06264
[Presentation] Enhanced Repair of Meniscal Hoop Structure Injuries Using an Aligned Electrospun Nanofibrous Scaffold Combined with a Mesenchymal Stem Cell-derived Tissue Engineered Construct.2019
- Author(s)
  Shimomura K, Rothrauff BB, Hart DA, Hamamoto S, Kobayashi M, Yoshikawa H, Tuan RS, Nakamura N
- Organizer
  International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06264
[Presentation] Repair of Meniscal Hoop Function Using an Aligned Electrospun Nanofibrous Scaffold Combined with a Mesenchymal Stem Cell-derived Tissue Engineered Construct.2019
- Author(s)
  Shimomura K, Hamamoto S, Kobayashi M, Yoshikawa H, Nakamura N
- Organizer
  Annual Meeting of the Japanese Society for Artificial Organs
- Data Source
  KAKENHI-PROJECT-16H06264
[Presentation] ナノレベル線維構造を有するスキャフォールドを用いた半月板フープ機能の修復2019
- Author(s)
  下村和範, Benjamin B. Rothrauff, David A. Hart, 濱本秀一, 小林雅人, 吉川秀樹, Rocky S. Tuan, 中村憲正
- Organizer
  日本再生医療学会
- Data Source
  KAKENHI-PROJECT-16H06264
[Presentation] 膝関節痛のマネジメント（シンポジウム3　「こうすれば解決！？コモンディジーズ」）2018
- Author(s)
  下村和範, 吉川秀樹, 中村憲正
- Organizer
  第11回日本運動器疼痛学会
- Data Source
  KAKENHI-PROJECT-16H06264

1. Nakamura Norimasa (50273719)

# of Collaborated Projects: 3 results

# of Collaborated Products: 38 results
2. Matsusaki Michiya (00419467)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Nakata Ken (00283747)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 弓削類 (20263676)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 紀ノ岡正博 (40234314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 落谷孝広 (60192530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 前達雄 (10569734)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 金本隆司 (20512049)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 辻井聡 (70898014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 下田浩 (20274748)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 宮川繁 (70544237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 三谷保弘 (50567071)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 小柳磨毅 (20269848)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 木村佳記 (00571829)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 植田篤史 (20982937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SAITO Taku

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 花井洋人

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
18. 吉川秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
19. 藤江裕道

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 千々松良太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimomura Kazunori 下村 和範

Research Projects

Research Products

Co-Researchers

膝蓋腱の力学特性と運動パフォーマンスとの関係からみたジャンパー膝の発生要因の解明

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細胞外小胞を徐放するナノファイバースキャフォールドを用いた新規半月板治療法の開発Principal Investigator

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Scientific understanding of heterogeneous interface joining of multiple tissues and ex vivo construction of locomotor models

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Development of in vivo-like 3D vascularized osteochondral tissuePrincipal Investigator

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Development of a safe and efficient methods for the collection of mesenchymal stem cell-derived extracellular vesichles for the treatment of osteoarthritis

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Investigation of the pathophysiology of knee osteoarthritis with an emphasis on PGE2 / NGF / MMP production mechanism by mechanical stimulation

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Repairing incurable meniscal tears using a novel nanofibrous scaffoldPrincipal Investigator

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線維の配向性を付与したスキャフォールドを用いた半月板横断裂に対する治療法の確立Principal Investigator

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[Book] Failed Cartilage Surgery (Chapter 8). Orthopaedic Sports Medicine - An Encyclopedic Review of Diagnosis, Prevention, and Management -.2023

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[Book] 特集「疲労骨折を克服する, 予防から最新の保存療法戦略まで」 疲労骨折に対するBiologics治療. 臨床スポーツ医学.2023

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[Book] 特集「変形性関節症：病態研究と治療の最前線」 滑膜間葉系幹細胞を用いた膝関節軟骨再生. Precision Medicine.2023

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[Book] ISAKOS/ICRS Book “Orthobiologics: Injectable Therapies for the Musculoskeletal System” Chapter 25: Cartilage Lesions and Osteoarthritis: Cell Therapy.2021

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[Book] ISAKOS Book “Advances in Knee Ligament and Knee Preservation Surgery” Chapter 37: Current Introduction of the Biological Agent Derived from Adipose Tissue to the Treatment of Knee Osteoarthritis.2021

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[Book] ISAKOS/ICRS Book “Early Osteoarthritis” Chapter 15: The Current Role of Stem Cell Therapy and iPS Cells.2021

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[Book] 膝関節鏡視下手術 (ビジュアル・サージカルテクニック) Chapter 4 診断：正常膝関節の鏡視所見2021

Shimomura Kazunori 下村和範

[Book] 特集「疲労骨折を克服する, 予防から最新の保存療法戦略まで」　疲労骨折に対するBiologics治療. 臨床スポーツ医学.2023

[Book] 特集「変形性関節症：病態研究と治療の最前線」　滑膜間葉系幹細胞を用いた膝関節軟骨再生. Precision Medicine.2023

[Book] 膝関節鏡視下手術 (ビジュアル・サージカルテクニック) Chapter 4　診断：正常膝関節の鏡視所見2021

[Journal Article] 解剖学的長方形骨孔前十字靱帯再建術における移植腱の違いによる成績比較－骨付き膝蓋腱vs骨付き大腿四頭筋腱－2023