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Ochiya Takahiro  落谷 孝広

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… Alternative Names

OCHIYA Takahiro  落谷 孝広

落合 孝広

OCHIAI Takahiro  落合 孝広

落谷 孝広  オチヤ タカヒロ

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Researcher Number 60192530
Other IDs
External Links
Affiliation (Current) 2025: 東京医科大学, 医学部, 特任教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 東京医科大学, 医学部, 特任教授
2019 – 2022: 東京医科大学, 医学部, 教授
2018 – 2019: 国立研究開発法人国立がん研究センター, 研究所, プロジェクトリーダー
2017: 国立研究開発法人国立がん研究センター, 研究所, 分野長
2017: 国立がん研究センター研究所, 分子細胞治療研究分野, 主任分野長 … More
2017: 独立行政法人国立がん研究センター, 分子細胞治療研究分野, 分野長
2015 – 2016: 国立研究開発法人国立がん研究センター, 研究所, 主任分野長
2011 – 2014: 独立行政法人国立がん研究センター, 研究所, 分野長
2013: 国立がん研究センター研究所, 分子細胞治 療研究分野, 分野長
2013: 国立がん研究センター研究所, 分子細胞治療研究分野, 分野長
2013: 独立行政法人国立がん研究センター研究所, 分子細胞治療研究分野, 分野長
2012: 国立がん研究センター, 研究所, 分子細胞治療研究分野長
2012: 独立行政法人国立がん研究センター, その他部局等, 分野長
2012: 独立行政法人国立がん研究センター, 分子細胞治療研究分野, 分野長
2012: 独立行政法人国立がん研究センター, 研究所, 分子細胞治療研究分野長
2011: 国立がんセンター(研究所及び東病院臨床開発センター), がん転移研究室, 即率室長
2011: 国立がんセンター研究所, 分子標的研究グループ, 分野長
2011: 国立がんセンター研究所, 分子細胞治療研究分野, 分野長
2011: 国立がん研究センター, 分子細胞治療研究分野・分野長, 分野長
2011: 国立がん研究センター研究所, がん転移研究室, 室長
2011: 独立行政法人国立がん研究センター, がん転移研究室, 室長
2010 – 2011: 国立がんセンター(研究所及び東病院臨床開発センター), がん転移研究室, 独立室長
2010: 北海道大学, 国立がんセンター研究所, 室長
2010: 国立がん研究センター, がん転移研究室, 独立室長
2010: 独立行政法人国立がん研究センター, 研究所, 研究分野長
2009: 国立がんセンター, 研究所, 室長
2009: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, がん転移研究室, 室長
2008 – 2009: 国立がんセンター研究所, 室長
2007 – 2009: 国立がんセンター, がん転移研究室, 独立室長
2008: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, がん転移研究室, 室長
2008: 群馬大学, 国立がんセンター・研究所, 室長
2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 国立がんセンター(研究所及び東病院臨床開発センター), 室長
2007: National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East, 研究所がん転移研究室, 独立室長
2007: 国立がんセンター研究所, がん転移研究室, 独立室長
2005 – 2006: 国立がんセンター(研究所及び東病院臨床開発センター), がん転移研究室, 室長
2004: 国立がんセンター(研究所), がん転移研究室, 室長
2003: 国立がんセンター研究所, がん転移研究室, 室長
2000 – 2002: 国立がんセンター, 研究所・がん転移研究室, 室長
1998: 国立がんセンター, 分子腫瘍学部, 室長
1988 – 1990: Osaka University,Research Associate, 細胞工学センター, 助手 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Basic Section 50010:Tumor biology-related
Except Principal Investigator
Basic Section 56030:Urology-related / Basic Section 56020:Orthopedics-related / Clinical oncology / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Orthopaedic surgery / Gastroenterology / Nanomaterials/Nanobioscience / Basic Section 55010:General surgery and pediatric surgery-related … More / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 57060:Surgical dentistry-related / Basic Section 55030:Cardiovascular surgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56010:Neurosurgery-related / Chemical biology / Digestive surgery / Virology / 分子遺伝学・分子生理学 / Tumor therapeutics / epigenetics / Human pathology / Biomedical engineering/Biological material science / Experimental pathology / Biological Sciences Less
Keywords
Principal Investigator
デリバリー / 転移 / 前立腺がん / 核酸医薬 / 遺伝子治療 / siRNA / ドラッグデリバリー / アテロコラーゲン / metastasis / breast cancer … More / RNA single-cell sequence / Cancer / Genetic profile / Single-cell RNA seq / Metastasis / Breast cancer / Single-cell analysis / in vivoイメージング / 骨転移 / リンパ節転移 / がん転移 / RNA干渉 / miRNA / microRNA / microR / 治療 / がん / DNAワクチン / 成体親和性物質 / プラスミドDNA / ウイルスベクター / トランスフェクションアレイ / アレイ / ハイスループット / 臓器特異的 / ナノ粒子 / メラノーマ / IL-2 / 接触性皮膚炎 / アンチセンス … More
Except Principal Investigator
エクソソーム / マイクロRNA / バイオマーカー / miRNA / microRNA / がん / 間葉系幹細胞 / 再生医療 / 核酸医薬 / 遺伝子 / 癌 / 癌細胞 / B型肝炎ウイルス / X遺伝子 / 肝癌 / リキッドバイオプシー / メタロプロテアーゼ / アミノ酸トランスポーター / AI / 変形性関節症 / 膵がん / 膵癌 / 肝細胞 / 悪性骨軟部腫瘍 / がん幹細胞 / タンパク質 / 骨肉腫 / 肉腫 / 骨軟部腫瘍 / DDS / メチル化 / エピジェネティクス / ナノカプセル / MRI造影剤 / 高機能性ナノカプセル / 自己組織化 / トランス活性化 / mRNA / 急性拒絶反応 / 腎移植 / 化学療法抵抗性 / 神経内分泌前立腺癌 / 去勢抵抗性前立腺癌 / 致死性前立腺癌 / バイオインフォマティックス解析 / セクレトーム / 組織修復 / バイオインフォマティクス解析 / セレクトーム / 細胞外分泌小胞 / CAR-T / デザイナー細胞 / 膵管内乳頭粘液性腫瘍 / 腫瘍性膵嚢胞 / EV / MRONJ / 薬剤関連顎骨壊死 / 破骨細胞 / 間葉系細胞 / 血管新生 / 下肢切断 / 創薬 / 重症下肢虚血 / 閉塞性動脈硬化症 / 分子標的創薬 / 泌尿器科がん / トランスポーター / RNA / 難治がん / RNA修飾 / 去勢抵抗性 / 前立腺がん / CRPC / Exosome / cfDNA / ARV7 / 4F2hc / L型アミノ酸トランスポーター / Liquid Biopsy / LAT1 / LAT3 / テストステロン / 前立腺癌 / 診断マーカー / 中枢神経系原発悪性リンパ腫 / reduced folate carrier / prognosis / Primary CNS lymphoma / chemotherapy / メタボローム解析 / MyD88 / biomarker / 大量メトトレキサート基盤化学療法 / primary CNS lymphoma / 化合物ライブラリ / 高置換 / CLiP / ヒト肝細胞 / シトクロームP450 / 低分子化合物 / リプログラミング / 肝前駆細胞 / 肝細胞移植 / 抗がん剤 / HSP90 / 共培養 / 抗癌剤 / バイオマーカー / 先端計測 / 遺伝子的多型因子 / 環境因子 / 癌代謝 / 先制医療 / 腫瘍遺伝子 / 環境 / 遺伝子多型 / 早期膵癌 / packaging signal sequence / packaging viral nucleic acid / fusion polypeptide / core protein / DNA polymerase / replication / hepatitis B virus / ウイルス粒子形成 / ウイルス感染 / 表面抗原遺伝子 / B型肝炎ウイルス(HBV) / 融合タンパク / 粒子形成 / DNAトランスフェクション / Pre S遺伝子 / PoC遺伝子 / 増殖 / パッケ-ジング・シグナル / 翻訳コドンの選択 / コアタンパク / DNAポリメラ-ゼ / トランスフェクション / Dual Laser / Cell Sorter / 染色体 / デュアルレーザー / セルソーター / 癌遺伝子1ca / エンハンサー / cMyc遺伝子 / トランスジェニックマウス / ウッドチャック肝癌 / ダックB型肝炎ウイルス / DNA組み込み / HBV / 全ゲノム解析 / 胞巣状軟部肉腫 / 全トランスクリプトーム解析 / 全エクソン解析 / ゼノグラフト / 軟骨肉腫 / 医療・福祉 / PDXモデル / プロテオーム解析 / エピゲノム解析 / ゲノム解析 / 粘液型脂肪肉腫 / 粘液線維肉腫 / アミノ酸アミダイト / C型肝炎ウイルス / miR-122 / miR-21 / miR-16 / iMIR / ドラッグデリバリー / ドラッグデリバリーシステム / iPS細胞 / 羊膜細胞 / 分子標的治療 / EGFR / SIRT1 / 細胞老化 / 胆管ネットワーク / スフェロイド / 極性 / 組織工学 / 胆管 / 球状凝集体 / 胆管上皮細胞 / 生物・生体工学 / 細胞・組織 / 再生医学 / 移植・再生医療 / マクロ組織極性 / 細胞・組織工学 / 抗がん剤感受性 / 蛍光二次元電気泳動 / 網羅的発現解析 / 予後因子 / 網羅的解析 / exome sequencing / 治療 / 外殻タンパク質 / ナノバイオ / ナノ材料 / ウイルス / バイオテクノロジー / ワクチン製剤 / アジュバント効果 / 高機能化 / ウイルス様粒子 / ウイルス外郭タンパク質 / 新規DDS用キャリア / 自己集合化 / ウイルス外殻タンパク質 / 分子標的 / 分子創薬 / D40,癌 / p53 nul 細胞 / がん細胞 / D40siRNA / p53 / RNA干渉 / 増殖抑制 / 細胞死 / D40 / 分裂破局死 / DNAメチル化 / マイクロアレイ / 肝再生 / 瀉血療法 / C型慢性肝炎 / 新規DDS / ナノカプセル誘導因子 / VP3 / VP2 / VP1五量体 / ウイルスカプシドタンパク質 / NMBA / MNU / 食道発がん / 導入遺伝子変異 / 乳腺発がん / 発がん感受性 / トランスジェニックラット / c-Ha-ras / CATアッセイ / ウイルスDNAの組込み / 11番染色体の変化 / サザンブロット / 致死的再編成 / 宿主染色体の再編成 / 感染細胞系 / 組込み / ウイルス発癌 / 癌遺伝子 / ヘパドナウイルス / 慢性肝炎 / ヒトB型肝炎ウイルス(HBV) Less
  • Research Projects

    (41 results)
  • Research Products

    (212 results)
  • Co-Researchers

    (112 People)
  •  がん幹細胞を標的とした「デザイナー細胞」療法の基盤構築

    • Principal Investigator
      石井 秀始
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      The University of Osaka
  •  変形性関節症への細胞外分泌小胞最適化:細胞間クロストークとマルチオミクス解析応用

    • Principal Investigator
      廣畑 聡
    • Project Period (FY)
      2025 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Okayama University
  •  変形性関節症に対する間葉系間質細胞由来セクレトーム治療における作用機序の解明

    • Principal Investigator
      中村 憲正
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  A Comprehensive Amino Acid Transporter-Based Therapeutic Strategy for Lethal Prostate Cancer

    • Principal Investigator
      坂本 信一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  エクソソームおよびマイクロRNA測定による新たな腎移植後慢性拒絶反応の診断法の開発

    • Principal Investigator
      岩本 整
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Tokyo Medical University
  •  腫瘍性膵嚢胞および膵癌の発癌早期予測を可能にする新規バイオマーカーの開発の研究

    • Principal Investigator
      島谷 昌明
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kansai Medical University
  •  xtracellular vesicles from mouse bone marrow macrophages-derived osteoclasts treated with zoledronic acid contain miR-146a-5p and miR-322-3p, which inhibit osteoclast function

    • Principal Investigator
      CHIKAZU Daichi
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Tokyo Medical University
  •  Transporter-targeted drug development against urological cancers by utilizing liquid biopsy and AI

    • Principal Investigator
      ANZAI Naohiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  Establishment of aminoacid transporter directed prostate cancer therapy based on the liquid biopsy

    • Principal Investigator
      Sakamoto Shinichi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Chiba University
  •  Maximum accuracy and application of diagnostic performance by integrated analysis of cancer exosome antigen and internal RNA information

    • Principal Investigator
      Ishii Hideshi
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Osaka University
  •  Decipher cell-cell interactions

    • Principal Investigator
      Hirohata Satoshi
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Okayama University
  •  A Study on Signal Transductions of MSC Culture in Total Autologous Angiogenic Therapy

    • Principal Investigator
      Fukuda Shoji
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Tokyo Medical University
  •  Single-cell analysis for the study of breast cancer metastasisPrincipal Investigator

    • Principal Investigator
      落谷 孝広
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Tokyo Medical University
  •  Exploration of diagnostic and therapeutic biomarkers in primary central nervous system lymphoma

    • Principal Investigator
      Mishima Kazuhiko
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56010:Neurosurgery-related
    • Research Institution
      Saitama Medical University
  •  Development of a safe and efficient methods for the collection of mesenchymal stem cell-derived extracellular vesichles for the treatment of osteoarthritis

    • Principal Investigator
      Nakamura Norimasa
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Osaka University
  •  Generation of hepatic progenitor cells from human hepatocytes using small molecules

    • Principal Investigator
      KATSUDA Takeshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Chemical biology
    • Research Institution
      National Cancer Center Japan
  •  Achievement of highly accurate diagnosis of early pancreatic cancer in Japanese patients through a comprehensive/integrated approach

    • Principal Investigator
      MORI Masaki
    • Project Period (FY)
      2015 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
      Osaka University
  •  The elucidation of the molecular mechanism about the acquisition of pancreatic cancer invasion ability and application to cancer therapy

    • Principal Investigator
      SHIMASAKI Takeo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kanazawa Medical University
  •  Development of biomarkers and novel therapeutic targets for malignant bone and soft tissue tumors using the methods of global expression analysis

    • Principal Investigator
      KAWAI AKIRA
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      National Cancer Center Japan
  •  Inhibition of microRNA functions by novel nucleic acids, iMIR

    • Principal Investigator
      EGUCHI Yutaka
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor therapeutics
    • Research Institution
      Osaka University
  •  Development of novel cancer specific DDS utilizing circulating microRNA-derived mechanism

    • Principal Investigator
      TAHARA Hidetoshi
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Clinical oncology
    • Research Institution
      Hiroshima University
  •  Mechanism of senescence-associated microRNA inhibiting cell growth and metastasis

    • Principal Investigator
      TAHARA Hidetoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Clinical oncology
    • Research Institution
      Hiroshima University
  •  Development of novel cancer therapy using miRNA containing exosome

    • Principal Investigator
      KURODA Masahiko
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Human pathology
    • Research Institution
      Tokyo Medical University
  •  Why methylation and demethylation occur simultaneously in cancers

    • Principal Investigator
      HATADA Izuho
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      epigenetics
    • Research Institution
      Gunma University
  •  Development of novel drug delivery system for micro RNA nucleic biomedicine using exosome from human cultured cells

    • Principal Investigator
      TAHARA Hidetoshi
    • Project Period (FY)
      2011
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Clinical oncology
    • Research Institution
      Hiroshima University
  •  Search for novel biomarkers and therapeutic targets of malignant bone and soft tissue tumors/sarcomas using the methods of global expression analysis

    • Principal Investigator
      KAWAI AKIRA
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Integrated in vit-roin vivo organization of liver tissues having a functional bile duct network

    • Principal Investigator
      SAKAI Yasuyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      The University of Tokyo
  •  Development of high-performance nano-carrier for next generation medicine

    • Principal Investigator
      HANDA Hiroshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Nanomaterials/Nanobioscience
    • Research Institution
      Tokyo Institute of Technology
  •  マイクロアレイによる肺癌のメチル化網羅的解析と診断・治療のターゲットの検討

    • Principal Investigator
      HATADA Izuho
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Gunma University
  •  Approach to Molecular Development of the Drug that induces Mitotic Catastrophe in Cancer cells

    • Principal Investigator
      TAKIMOTO Masato
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Experimental pathology
    • Research Institution
      Hokkaido University
  •  Development and application of functionalized nanocapsules

    • Principal Investigator
      HANDA Hiroshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Nanomaterials/Nanobioscience
    • Research Institution
      Tokyo Institute of Technology
  •  Establishing a new therapeutic strategy for liver failure by recycling phlebotomized blood cells

    • Principal Investigator
      MATSUMOTO NOBUYUKI
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      St.Marianna University School of Medicine
  •  Atelocollagen-mediated delivery of nucleic acid medicinesPrincipal Investigator

    • Principal Investigator
      OCHIYA Takahiro
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  アテロコラーゲン包埋法の応用Principal Investigator

    • Principal Investigator
      落谷 孝広
    • Project Period (FY)
      2000 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  c-Ha-rasトランスジェニックラットの発がん感受性の解析

    • Principal Investigator
      鳥山 弘靖
    • Project Period (FY)
      1997 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      National Cancer Center Research Institute and Research Center for Innovative Oncology, National Cancer Center Hospital East
  •  B型肝炎ウイルスの増殖に関わる因子の研究

    • Principal Investigator
      松原 謙一
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  肝炎ウイルスと肝癌発生

    • Principal Investigator
      村上 清史
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  B型肝炎ウイルスの増殖・組込みと肝癌発生との関連

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  肝炎ウイルスと肝癌発生

    • Principal Investigator
      服部 信
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      Kanazawa University
  •  Studies on the Mechanism of Infection and Replication of Hepatitis B Virus

    • Principal Investigator
      MATSUBARA Kenichi
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Osaka University
  •  Development of chromosome sorting techniques using a dual laser chromosome sorter

    • Principal Investigator
      MATSUBARA Kenichi, 室津 知明
    • Project Period (FY)
      1986 – 1988
    • Research Category
      Grant-in-Aid for Developmental Scientific Research
    • Research Field
      分子遺伝学・分子生理学
    • Research Institution
      Osaka University

All 2025 2024 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation Book Patent

  • [Book] Epigenetic Biomarkers and Diagnostics, 1st Edition.2015

    • Author(s)
      Fujiwara T, Fujita Y, Nezu Y, Kawai A, Ozaki T, Ochiya T.
    • Publisher
      Academic Press, Inc.
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Book] The potential role of MicroRNA-based therapy for lung cancer stem cells.2014

    • Author(s)
      Fujita Y, Kuwano K, OchiyaT.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Book] Challenges and strategies for pulmonary delivery of microRNA-based therapeutics.2014

    • Author(s)
      Fujita Y, Kuwano K, Ochiya T.
    • Publisher
      Springer
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Book] Fetal Tissue Transplantation in Fetal Tissue Transplantation(分担執筆),2013

    • Author(s)
      Y. Sakai1, J. Jiang, S. Hanada, H. Huang, T. Katsuda, N. Kojima, T. Teratani, A. Miyajima, T. Ochiya
    • Total Pages
      221
    • Publisher
      Springer-Verlag UK
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Book] Springer-Verlag UK,2212013

    • Author(s)
      Y. Sakai, J. Jiang, S. Hanada, H. Huang,T.Katsuda, N. Kojima, T. Teratani, A.Miyajima, T.Ochiya
    • Total Pages
      221
    • Publisher
      Fetal TissueTransplantation in Fetal TissueTransplantation
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Book] siRNA and miRNA Gene Silencing.(Sioud M (ed), Local and systemic delivery of siRNAs for oligonucleotide therapy.)2009

    • Author(s)
      Takeshita F, Hokaiwado N, Honma K, Banas A, Ochiya T.
    • Publisher
      Humana Press
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Book] Role of cancer stem cells in cancer biology and therapy

    • Author(s)
      Kawai A, Ochiya T, etc
    • Publisher
      USA, CRC Press
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Book] Cancer stem cells of sarcoma

    • Author(s)
      Kawai A, Ochiya T, etc
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Journal Article] Extracellular vesicles from mouse bone marrow macrophages-derived osteoclasts treated with zoledronic acid contain miR-146a-5p and miR-322-3p, which inhibit osteoclast function2025

    • Author(s)
      Minami Sakura、Fujii Yasuyuki、Yoshioka Yusuke、Hatori Ayano、Kaneko Kotaro、Ochiya Takahiro、Chikazu Daichi
    • Journal Title

      Bone

      Volume: 190 Pages: 117323-117323

    • DOI

      10.1016/j.bone.2024.117323

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K10230, KAKENHI-PROJECT-23K16133
  • [Journal Article] Extracellular vesicles as novel uro-oncology biomarkers: insights toward clinical applications2024

    • Author(s)
      Urabe Fumihiko、Tamura Takaaki、Sakamoto Shinichi、Kimura Takahiro、Ochiya Takahiro
    • Journal Title

      Current Opinion in Urology

      Volume: 35 Issue: 1 Pages: 13-18

    • DOI

      10.1097/mou.0000000000001194

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24K02575
  • [Journal Article] Extracellular vesicles in bone homeostasis: key roles of physiological and pathological conditions2022

    • Author(s)
      Tamura Takaaki、Yoshioka Yusuke、Sakamoto Shinichi、Ichikawa Tomohiko、Ochiya Takahiro
    • Journal Title

      Journal of Bone and Mineral Metabolism

      Volume: - Issue: 3 Pages: 345-357

    • DOI

      10.1007/s00774-022-01362-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-20K09555
  • [Journal Article] Biological Functions Driven by mRNAs Carried by Extracellular Vesicles in Cancer.2021

    • Author(s)
      Prieto-Vila M, Yoshioka Y, Ochiya T.
    • Journal Title

      Front Cell Dev Biol.

      Volume: 9

    • DOI

      10.3389/fcell.2021.620498

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Journal Article] Extracellular Vesicles in Bone Metastasis: Key Players in the Tumor Microenvironment and Promising Therapeutic Targets2020

    • Author(s)
      Tamura Takaaki、Yoshioka Yusuke、Sakamoto Shinichi、Ichikawa Tomohiko、Ochiya Takahiro
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 18 Pages: 6680-6680

    • DOI

      10.3390/ijms21186680

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K09555, KAKENHI-PROJECT-20H03813
  • [Journal Article] Extracellular vesicles as biomarkers and therapeutic targets for cancer.2020

    • Author(s)
      Urabe, F., (4名略), Ochiya, T.
    • Journal Title

      Am. J. Physiol Cell Physiol.

      Volume: 318(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05791
  • [Journal Article] MicroRNA-124a inhibits endoderm lineage commitment by targeting Sox17 and Gata6 in mouse embryonic stem cells.2020

    • Author(s)
      Liew, LC., (5名略), Ochiya, T.
    • Journal Title

      Stem Cells.

      Volume: 38(4) Issue: 4 Pages: 504-515

    • DOI

      10.1002/stem.3136

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05791
  • [Journal Article] Development and Validation of an Esophageal Squamous Cell Carcinoma Detection Model by Large-Scale MicroRNA Profiling.2019

    • Author(s)
      Sudo, K., (12名略), Ochiya, T.
    • Journal Title

      JAMA Netw Open.

      Volume: 2(5) Issue: 5 Pages: e194573-e194573

    • DOI

      10.1001/jamanetworkopen.2019.4573

    • Data Source
      KAKENHI-PROJECT-15H05791
  • [Journal Article] Genetic manipulation of autonomic nerve fiber innervation and activity and its effect on breast cancer progression2019

    • Author(s)
      Kamiya Atsunori、Hayama Yohsuke、Kato Shigeki、Shimomura Akihiko、Shimomura Takushi、Irie Katsumasa、Kaneko Ryosuke、Yanagawa Yuchio、Kobayashi Kazuto、Ochiya Takahiro
    • Journal Title

      Nature Neuroscience

      Volume: 22 Issue: 8 Pages: 1289-1305

    • DOI

      10.1038/s41593-019-0430-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K22474, KAKENHI-PROJECT-18K16408, KAKENHI-PUBLICLY-18H04707, KAKENHI-PUBLICLY-19H04895, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-17H04365, KAKENHI-PROJECT-18K19950, KAKENHI-PROJECT-17K17795, KAKENHI-PROJECT-15KK0331
  • [Journal Article] Exploiting the message from cancer: the diagnostic value of extracellular vesicles for clinical applications.2019

    • Author(s)
      Kosaka, N., (5名略), Ochiya, T.
    • Journal Title

      Exp. Mol. Med.

      Volume: 51(3) Issue: 3 Pages: 1-9

    • DOI

      10.1038/s12276-019-0219-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05791
  • [Journal Article] Extracellular vesicles mediate the horizontal transfer of an active LINE-1 retrotransposon.2019

    • Author(s)
      Kawamura, Y., Sanchez, Calle, A., Yamamoto, Y., Sato, TA., Ochiya, T.
    • Journal Title

      J. Extracell, Vesicles,

      Volume: 8(1) Issue: 1 Pages: 1643214-1643214

    • DOI

      10.1080/20013078.2019.1643214

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05791
  • [Journal Article] Towards Circulating-Tumor DNA-Based Precision Medicine.2019

    • Author(s)
      Hironaka-Mitsuhashi, A., Sanchez, Calle, A., Ochiya, T., Takayama, S., Suto, A.
    • Journal Title

      J. Clin. Med.

      Volume: 8(9) Issue: 9 Pages: 8091365-8091365

    • DOI

      10.3390/jcm8091365

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H05791
  • [Journal Article] Usefulness of serum microRNA as a predictive marker of recurrence and prognosis in biliary tract cancer after radical surgery.2019

    • Author(s)
      Akazawa, Y., (4名略), Ochiya, T., Nakamoto, Y., Nakatsura, T.
    • Journal Title

      Sci Rep.

      Volume: 9(1) Issue: 1 Pages: 5925-5925

    • DOI

      10.1038/s41598-019-42392-7

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-19H03637
  • [Journal Article] Cancer Extracellular Vesicles Contribute to Stromal Heterogeneity by Inducing Chemokines in Cancer-Associated Fibroblasts2019

    • Author(s)
      Naito Y, Yamamoto Y, Sakamoto N, Shimomura I, Kogure A, Kumazaki M, Yokoi A, Yashiro M, Kiyono T, Yanagihara K, Takahashi RU, Hirakawa K, Yasui W, Ochiya T.
    • Journal Title

      Oncogene

      Volume: 38 Issue: 28 Pages: 5566-5579

    • DOI

      10.1038/s41388-019-0832-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07017, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-18H02883, KAKENHI-PROJECT-19H03443, KAKENHI-PROJECT-17H04991
  • [Journal Article] Distinct methylation levels of mature microRNAs in gastrointestinal cancers2019

    • Author(s)
      Konno Masamitsu、Koseki Jun、Asai Ayumu、Yamagata Akira、Shimamura Teppei、Motooka Daisuke、Okuzaki Daisuke、Kawamoto Koichi、Mizushima Tsunekazu、Eguchi Hidetoshi、Takiguchi Shuji、Satoh Taroh、Mimori Koshi、Ochiya Takahiro、Doki Yuichiro、Ofusa Ken、Mori Masaki、Ishii Hideshi
    • Journal Title

      Nature Communications

      Volume: 10 Issue: 1 Pages: 3888-3888

    • DOI

      10.1038/s41467-019-11826-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08617, KAKENHI-PROJECT-18K08704, KAKENHI-PROJECT-19K07688, KAKENHI-PROJECT-19K09172, KAKENHI-PROJECT-19K22658, KAKENHI-PROJECT-18KK0251, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-17H04282, KAKENHI-PROJECT-19H03715, KAKENHI-PROJECT-18K16355, KAKENHI-PROJECT-18K16356, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06279
  • [Journal Article] 成熟肝細胞からの,高い再生能を有しかつ培養可能な肝前駆細胞へのリプログラミング2018

    • Author(s)
      勝田毅、落谷孝広
    • Journal Title

      再生医療

      Volume: 17 Pages: 78-84

    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] Generation of Chemically Induced Liver Progenitors (CLiPs) from Rat Adult Hepatocytes2018

    • Author(s)
      Katsuda Takeshi、Hosaka Kazunori、Ochiya Takahiro
    • Journal Title

      BIO-PROTOCOL

      Volume: 7 Issue: 2 Pages: 1-26

    • DOI

      10.21769/bioprotoc.2689

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] Chemically induced liver progenitors (CLiPs): a novel cell source for hepatocytes and biliary epithelial cells2017

    • Author(s)
      Takeshi Katsuda, Takahiro Ochiya
    • Journal Title

      Methods in Molecular Biology

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] Generation of hepatic organoids with biliary structures2017

    • Author(s)
      Takeshi Katsuda, Takahiro Ochiya, Yasuyuki Sakai
    • Journal Title

      Methods in Molecular Biology

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] 低分子化合物による成熟肝細胞から肝前駆細胞へのin vitroリプログラミング (特集 再生医療の新規知見と発展)2017

    • Author(s)
      勝田毅、落谷孝広
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 68 Pages: 363-368

    • NAID

      40021346807

    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] Biological and clinical insights offered by chemically induced liver progenitors (CLiPs)2017

    • Author(s)
      Katsuda Takeshi、Ochiya Takahiro
    • Journal Title

      Stem Cell Investigation

      Volume: 4 Pages: 68-68

    • DOI

      10.21037/sci.2017.08.04

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity2017

    • Author(s)
      Katsuda T, Kawamata M, Hagiwara K, Takahashi RU, Yamamoto Y, Camargo FD, Ochiya T
    • Journal Title

      Cell Stem Cell

      Volume: 20 Issue: 1 Pages: 41-55

    • DOI

      10.1016/j.stem.2016.10.007

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] Exploration for Cell Sources for Liver Regenerative Medicine: “CLiP” as a Dawn of Cell Transplantation Therapy2017

    • Author(s)
      Kazunori Hosaka, Takeshi Katsuda, Shuji Terai, Takahiro Ochiya
    • Journal Title

      Stem Cells and Cancer in Hepatology

      Volume: 印刷中

    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Journal Article] PAI-1, a target gene of miR-143, regulates invasion and metastasis by upregulating MMP-13 expression of human osteosarcoma.2016

    • Author(s)
      Hirahata M, Osaki M, Kanda Y, Sugimoto Y, Yoshioka Y, Kosaka N, Takeshita F, Fujiwara T, Kawai A, Ito H, Ochiya T, Okada F.
    • Journal Title

      Cancer Med

      Volume: - Issue: 5 Pages: 892-902

    • DOI

      10.1002/cam4.651

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15J07285, KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-26460472
  • [Journal Article] miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcoma.2016

    • Author(s)
      Kubota D, Kosaka N, Fujiwara T, Yoshida A, Arai Y, Qiao Z, Takeshita F, Ochiya T, Kawai A, Kondo T.
    • Journal Title

      Sarcoma.

      Volume: 2016 Pages: 1390571-1390571

    • DOI

      10.1155/2016/1390571

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-16K10880
  • [Journal Article] miR-135b, a key regulator of malignancy, is linked to poor prognosis in human myxoid liposarcoma.2016

    • Author(s)
      Nezu Y, Hagiwara K, Yamamoto Y, Fujiwara T, Matsuo K, Yoshida A, Kawai A, Saito T, Ochiya T.
    • Journal Title

      Oncogene.

      Volume: 35 Issue: 48 Pages: 6177-6188

    • DOI

      10.1038/onc.2016.157

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Journal Article] Control of HCV Replication with iMIRs, a Novel Anti-RNAi Agent2015

    • Author(s)
      Saori Itami, Yutaka Eguchi, Takayuki Mizutani, Eriko Aoki, Tadaaki Ohgi, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Hiroshi I Suzuki, Norifumi Kawada and Yoshiki Murakami
    • Journal Title

      Molecular Therapy Nucleic Acids

      Volume: 4 Pages: e219-e219

    • DOI

      10.1038/mtna.2014.71

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25640090, KAKENHI-PROJECT-15K08649, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-25293110
  • [Journal Article] miRNAの発現抑制による骨肉腫を含むがん治療への応用2014

    • Author(s)
      藤原智洋, 尾崎敏文, 川井章, 落谷孝広
    • Journal Title

      医薬ジャーナル

      Volume: 50 Pages: 97-104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Journal Article] Circulating microRNAs in sarcoma : potential biomarkers for diagnosis and targets for therapy2014

    • Author(s)
      Fujiwara T, Kawai A, Ochiya T
    • Journal Title

      Chemotherapy

      Volume: 3 Issue: 7 Pages: 757-773

    • DOI

      10.1007/s10585-012-9502-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Journal Article] Clinical relevance and therapeutic significance of microRNA-133a expression profiles and functions in malignant osteosarcoma-initiating cells.2014

    • Author(s)
      Fujiwara T, Katsuda T, Hagiwara K, Kosaka N, Yoshioka Y, Takahashi RU, Takeshita F, Kubota D, Kondo T, Ichikawa H, Yoshida A, Kobayashi E, Kawai A, Ozaki T, Ochiya T.
    • Journal Title

      Stem Cells.

      Volume: 32 Issue: 4 Pages: 959-973

    • DOI

      10.1002/stem.1618

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-13J07391, KAKENHI-PROJECT-22390296, KAKENHI-PROJECT-24591626, KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-26870877
  • [Journal Article] DSE-FRET : A new anticancer drug screening assay for DNA binding proteins2014

    • Author(s)
      Miyagi T, Shiotani B, Miyoshi R, Yamamoto T, Oka T, Umezawa K, Ochiya T, Takano M, Tahara H
    • Journal Title

      Cancer Sci.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24650645
  • [Journal Article] DSE-FRET : A new anticancer drug screening assay for DNA binding proteins2014

    • Author(s)
      Miyagi T, Shiotani B, Miyoshi R, Yamamoto T, Oka T, Umezawa K, Ochiya T, Takano M, Tahara H
    • Journal Title

      Cancer Sci

      Volume: (in press) Issue: 7 Pages: 870-874

    • DOI

      10.1111/cas.12420

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23300363, KAKENHI-PROJECT-24650645, KAKENHI-PUBLICLY-25112711, KAKENHI-PROJECT-25701005, KAKENHI-PROJECT-26290047, KAKENHI-PROJECT-26310106, KAKENHI-PROJECT-26640091, KAKENHI-PROJECT-221S0001
  • [Journal Article] The role of microRNAs in the regulation of cancer stem cells.2014

    • Author(s)
      Takahashi RU, Miyazaki H, Ochiya T.
    • Journal Title

      Front Genet

      Volume: 4 Pages: 295-295

    • DOI

      10.3389/fgene.2013.00295

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293342, KAKENHI-PROJECT-26870877
  • [Journal Article] Biliaryepithelial cells play an essential role inthe reconstruction of hepatic tissue witha functional bile ductular network2013

    • Author(s)
      Takeshi Katsuda, N. Kojima, TakahiroOchiya, and Yasuyuki Sakai.
    • Journal Title

      TissueEng. A

      Volume: in press.

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] Human adipose tissue・derived mesenchymal stem cells secrete functionalneprilysin-bound exosomes.2013

    • Author(s)
      Katsuda T, Tsuchiya R, Kosaka N, Yoshioka Y, Takagaki K, Oki K, Takeshita F, Sakai Y, Kuroda M, Ochiya T.
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: 3 Issue: 1 Pages: 1197-1197

    • DOI

      10.1038/srep01197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J04220, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PLANNED-21115008
  • [Journal Article] Hypoxiaefficiently induces differentiation ofmouse embryonic stem cells into endodermaland hepatic progenitor cells2013

    • Author(s)
      Takeshi Katsuda, Takumi Teratani,Mohammad,Mahfuz Chowdhury, TakahiroOchiya, Yasuyuki Sakai
    • Journal Title

      Biochemical Engineering Journal

      Volume: 74 Pages: 95-101

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] Hypoxia efficiently induces differentiation of mouse embryonic stem cells into endodermal and hepatic progenitor cells2013

    • Author(s)
      Takeshi Katsuda, Takumi Teratani, Mohammad Mahfuz Chowdhury, Takahiro Ochiya, Yasuyuki Sakai
    • Journal Title

      Biochemical Engineering Journal

      Volume: 74 Pages: 95-101

    • DOI

      10.1016/j.bej.2013.02.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] LGR5-positive colon cancer stem cells interconvert with drug-resistant LGR5-negative cells and are capable of tumor reconstitution2012

    • Author(s)
      Kobayashi S, Yamada-Okabe H, Suzuki M, Natori O, Kato A, Ochiya T, Kuroda M. (22名 20 番目)
    • Journal Title

      Stem Cells

      Volume: 30(12) Issue: 12 Pages: 2631-44

    • DOI

      10.1002/stem.1257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
  • [Journal Article] Dental and Medical Research.2012

    • Author(s)
      Ochiya T
    • Journal Title

      Dent Med Res

      Volume: 32 Pages: 158-161

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Journal Article] Systemically injected exosomes targeted to EGFR deliver anti-tumor microRNA to breast cancer cells2012

    • Author(s)
      後藤 典子
    • Journal Title

      Molecular Therapy

      Volume: 21 Issue: 1 Pages: 185-191

    • DOI

      10.1038/mt.2012.180

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-22130009, KAKENHI-PROJECT-23390062, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23590417, KAKENHI-PROJECT-23590993, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626
  • [Journal Article] Efficacy of a novel class of RNA interference therapeutic agents2012

    • Author(s)
      Hamasaki T, Suzuki H, Shirohzu H, Matsumoto T, D'Alessandro-Gabazza CN,Gil-Bernabe P, Boveda-Ruiz D, Naito M, Kobayashi T, Toda M, Mizutani T, TaguchiO, Morser J, Eguchi Y, Kuroda M, Ochiya T, Hayashi H, Gabazza EC, Ohgi T
    • Journal Title

      PLoS One

      Volume: 7 Issue: 8 Pages: 1-15

    • DOI

      10.1371/journal.pone.0042655

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590859, KAKENHI-PROJECT-23390087, KAKENHI-PROJECT-23659192, KAKENHI-PROJECT-23659626, KAKENHI-PROJECT-24591128
  • [Journal Article] miR-22 represses cancer progression by inducing cellular senescence2011

    • Author(s)
      Xu D, Takeshita F,他 10人
    • Journal Title

      J. Cell Biol.

      Volume: 193 Issue: 2 Pages: 409-424

    • DOI

      10.1083/jcb.201010100

    • Peer Reviewed
    • Data Source
      KAKENHI-PLANNED-21115008, KAKENHI-PROJECT-23300363, KAKENHI-PROJECT-23650626
  • [Journal Article] MicroRNA-143 Regulates Human Osteosarcoma Metastasis by Regulating Matrix Metalloprotease-13 Expression2011

    • Author(s)
      Osaki M, Takeshita F, Sugimoto Y, Kosaka N, Yamamoto Y, Yoshioka Y, Kobayashi E, Yamada T, Kawai A, Inoue T, Ito H, Oshimura M, Ochiya T
    • Journal Title

      Molecular Therapy

      Volume: 19(6) Issue: 6 Pages: 1123-1130

    • DOI

      10.1038/mt.2011.53

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10J04220, KAKENHI-PLANNED-21115008, KAKENHI-PROJECT-22390296, KAKENHI-PROJECT-23570005, KAKENHI-PROJECT-23650597
  • [Journal Article] miR-22 represses cancer progressionby inducing cellular senescence2011

    • Author(s)
      D. Xu, F. Takeshita, Y. Hino, S. Fukunaga, Y. Kudo, A. Tamaki, J. Matsunaga, R. Takahashi, T. Takata, A. Shimamoto, T. Ochiya, H. Tahara
    • Journal Title

      J. Cell Biology

      Volume: 193 Pages: 409-442

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23650626
  • [Journal Article] 脂肪由来幹細胞による細胞治療の可能性2011

    • Author(s)
      勝田 毅、酒井 康行、落谷 孝広
    • Journal Title

      実験医学

      Volume: 29 Pages: 3102-3108

    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes.2010

    • Author(s)
      Takeahita F, Patrawala L, Osaki M, Takahashi R, Yamamoto Y, Kosaka N, Kawamata M, Kelnar K, Bader AG, Brown D, Ochiya T.
    • Journal Title

      Mol Ther 18

      Pages: 181-187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] 異所性体内埋め込み型人工肝臓開発の現状と展望2010

    • Author(s)
      勝田 毅、小森 喜久夫、寺谷 工、落谷孝広、酒井 康行
    • Journal Title

      生産研究

      Volume: 62 Pages: 213-217

    • NAID

      130000342799

    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA.2010

    • Author(s)
      Tanooka H, Tatsumi K, Tsuji H, Noda Y, Katsube T, Ishii H, Ootsuyama A, Takeshita F, Ochiya T.
    • Journal Title

      Cancer Gene Ther 17

      Pages: 1-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Transplantation of fetal livercell-loaded hyaluronic acid sponge ontothe mesentery recovers a Wilson' sdisease model rat2010

    • Author(s)
      Katsuda T, Teratani T, Ochiya T, SakaiY
    • Journal Title

      J Biochem

      Volume: 148 Pages: 281-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] Mutant mouse p53 transgene elevates the chemical induction of tumors that respond to gene silencing with siRNA.2010

    • Author(s)
      anooka H, Tatsumi K, Tsuji H, Noda Y, Katsube T, Ishii H, Ootsuyama A, Takeshita F, Ochiya T.
    • Journal Title

      Cancer Gene Ther 17

      Pages: 1-10

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] 異所性体内埋め込み型人工肝暇開発の現状と展望2010

    • Author(s)
      勝田毅, 小森喜久夫, 寺谷工, 落谷孝広, 酒井康行
    • Journal Title

      生産研究

      Volume: 62 Pages: 213-217

    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] 1Yansplantation of a fetal liver ce11-loaded hyaluronic acid spongeonto the mesentery recovers a Wilson's disease model rat2010

    • Author(s)
      Katsuda T, Teratani T, OchiyaT, Sakai Y
    • Journal Title

      J Biochem.

      Volume: 148 Pages: 281-288

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] 間葉系幹細胞を用いた細胞治療の可能性2010

    • Author(s)
      勝田 毅、酒井 康行、落谷 孝広
    • Journal Title

      医工学治療

      Volume: 22 Pages: 204-210

    • Data Source
      KAKENHI-PROJECT-22650108
  • [Journal Article] Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes.2010

    • Author(s)
      Takeshita F, Patrawala L, Osaki M, Takahashi R, Yamamoto Y, Kosaka N, Kawamata M, Kelnar K, Bader AG, Brown D, Ochiya T.
    • Journal Title

      Mol Ther 18

      Pages: 181-187

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Sioud M (eds)2009

    • Author(s)
      Takeshita F, Hokaiwado N, Honma K, Banas A, Ochiya T
    • Journal Title

      Local and systemic delivery of siRNAs for oligonucleotide therapy

      Pages: 83-92

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] MicroRNA-500 as a potential diagnostic marker for hepatocellular carcinoma.2009

    • Author(s)
      Yamamoto Y, Kosaka N, Tanaka M, Koizumi F, Kanai Y, Mizutani T, Murakami Y, Kuroda M, Miyajima A, Kato T, Ochiya T.
    • Journal Title

      Biomarkers 14

      Pages: 529-538

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Dicer is required for maintaining adult pancreas.2009

    • Author(s)
      Morita S, Hara A, Kojima I, Horii T, Kimura M, Kitamura T, Ochiya T, Nakanishi K, Matoba R, Matsubara K, Hatada I.
    • Journal Title

      PLoS ONE 4

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Dicer is required for maintaining adult pancreas2009

    • Author(s)
      Morita S, Hara A, Kojima I, Horii T, Kimura M, Kitamura T, Ochiya T, Nakanishi K, Matoba R, Matsubara K, Hatada I
    • Journal Title

      PLoS ONE 4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] Local and systemic delivery of siRNAs for oligonucleotide therapy.2009

    • Author(s)
      Takeshita F, Hokaiwado N, Honma K, Banas A, Ochiya T.
    • Journal Title

      Methods Mol Biol 487

      Pages: 83-92

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Screening of potential molecular targets for colorectal cancer therapy.2009

    • Author(s)
      Honma K, Takemasa I, Matoba R, Yamamoto Y, Takeshita F, Mori M, Monden M, Matsubara K, Ochiya T.
    • Journal Title

      Int J Gen Med 2

      Pages: 243-257

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Presentation of Functional foreign peptides on the surface of SV40 virus-like particles2008

    • Author(s)
      Takahashi R, Kanesashi S, Inoue T, Enomoto T, Kawano M, Tsukamoto H, Takeshita F, Imai T, Ochiya T, Kataoka K, Yamaguchi Y, Handa H
    • Journal Title

      J Biotechnol 135

      Pages: 385-392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Presentation of functional foreign peptides on the surface of SV40 virus-like particles.2008

    • Author(s)
      Takahashi, R-H., Kanesashi, S-N., Inoue, T., Enomoto, T., Kawano, M-A., Tsukamoto, H., Takeshita, F., Imai, T., Ochiya, T., Kataoka, K., Yamaguchi, Y., Handa, H.
    • Journal Title

      J. Biotechnol 135

      Pages: 385-392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201024
  • [Journal Article] Antitumor effect of SN-38-releasing polymeric micelles, NK012, on spontaneous peritoneal metastases from orthotopic gastric cancer in mice compared with irinotecan.2008

    • Author(s)
      akajima TE, Yanagihara K, Takigahira M, Yasunaga M, Kato K, Hamaguchi T, Yamada Y, Shimada Y, Mihara K, Ochiya T, Matsumura Y.
    • Journal Title

      Cancer Res 68

      Pages: 9318-9322

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Tissue array substratum composed of histological sections: a new platform for orienting differentiation of embryonic stem cells towards hepatic linage2008

    • Author(s)
      Takeuchi T, Ochiya T, Takezawa T
    • Journal Title

      Tissue Eng Part A 14

      Pages: 267-274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Establishment of rat embryonic stem cells and making of chimera rats2008

    • Author(s)
      Ueda S, Kawamata M, Teratani T, Shimizu T, Tamai Y, Ogawa H, Hayashi K, Tsuda H, Ochiya T
    • Journal Title

      PLoS ONE 3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Glutathione S-transferase Pi mediates proliferation of andorogen-independent prostate cancer cells2008

    • Author(s)
      Hokaiwado N, Takeshita F, Naiki-Ito A, Asamoto M, Ochiya T, Shirai T
    • Journal Title

      Carcinogenesis 29

      Pages: 1134-1138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Pancreatic endocrine and exocrine cell ontogeny from renal capsule-transplanted embryonic stem cells in streptozocin-injured mice2008

    • Author(s)
      Kodama M, Takeshita F, Kanegasaki S, Ochiya T, Quinn G
    • Journal Title

      J Histochem Cytochem 56

      Pages: 33-44

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] RNAi-based drug discovery and its application to therapeutics2008

    • Author(s)
      Hokaiwado N, Takeshita F, Banas A, Ochiya T
    • Journal Title

      IDrugs 11

      Pages: 274-278

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Glutathione S-transferase Pi mediates proliferation of andorogen-independent prostate cancer cells.2008

    • Author(s)
      Hokaiwado N, Takeshita F, Naiki-Ito A, Asamoto M, Ochiya T, Shirai T.
    • Journal Title

      Carcinogenesis 29

      Pages: 1134-1138

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] MicroRNAs as biomarkers and therapeutic drugs in human cancer2008

    • Author(s)
      Osaki M, Takeshita F, Ochiya T
    • Journal Title

      Biomarkers 13

      Pages: 658-670

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells2008

    • Author(s)
      Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T.
    • Journal Title

      FEBS J 275

      Pages: 1260-1273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20012009
  • [Journal Article] An siRNA against JC virus (JCV) agnoprotein inhibits JCV infection in JCV-producing cells inoculated in nude mice2008

    • Author(s)
      Matoba T, Orba Y, Suzuki T, Makino Y, Shichinohe H, Kuroda S, Ochiya T, Itoh H, Tanaka S, Nagashima K, Sawa H
    • Journal Title

      Neuropathology 28

      Pages: 286-294

    • NAID

      10029319514

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] An siRNA against JC virus (JCV) agnoprotein inhibits JCV infection in JCV-producing cells inoculated in nude mice.2008

    • Author(s)
      Matoba T, Orba Y, Suzuki T, Makino Y, Shichinohe H, Kuroda S, Ochiya T, Itoh H, Tanaka S, Nagashima K, Sawa H.
    • Journal Title

      Neuropathology. 28

      Pages: 286-294

    • NAID

      10029319514

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Presentation of functional foreign peptides on the surface of SV40 virus-like particles2008

    • Author(s)
      Takahashi, R-H., Kanesashi, S-N., Inoue, T., Enomoto, T., Kawano, M-A., Tsukamoto, H., Takeshita, F., Imai, T., Ochiya, T., Kataoka, K., Yamaguchi, Y. and Handa, H
    • Journal Title

      J. Biotechnol 135

      Pages: 385-392

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19201024
  • [Journal Article] Down regulation of BRCA2 causes radio-sensitization of human tumor cells in vitro and in vivo.2008

    • Author(s)
      Yu D, Sekine E, Fujimori A, Ochiya T, Okayasu R.
    • Journal Title

      Cancer Sci 99

      Pages: 810-815

    • NAID

      10024005276

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] RNAi-based drug discovery and its application to therapeutics.2008

    • Author(s)
      Hokaiwado N, Takeshita F, Banas A, Ochiya T.
    • Journal Title

      IDrugs 11

      Pages: 274-278

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Presentation of functional foreign peptides on the surface of SV40 virus-like particles.2008

    • Author(s)
      Takahashi R, Kanesashi S, Inoue T, Enomoto T, Kawano M, Tsukamoto H, Takeshita F, Imai T, Ochiya T, Kataoka K, Yamaguchi Y, Handa H.
    • Journal Title

      J Biotechnol 135

      Pages: 385-392

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Optical imaging of RNAi-mediated silencing of cancer.2008

    • Author(s)
      Ochiya T, Honma K, Takeshita F, Nagahara S.
    • Journal Title

      Proc of SPIE 6868

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] An siRNA against JC virus (JCV)agnoprotein inhibits JCV infection in JCV-producingcells inoculated in nude mice2008

    • Author(s)
      Matoba T, Orba Y, Suzuki T, Makino Y, Shichinohe H, Kuroda S, Ochiya T, ltoh H, Tanaka S, Nagashima K, Sawa H.
    • Journal Title

      Neuropathology 28(3)

      Pages: 286-294

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] RPN2 gene confers docetaxel resistance in breast cancer.2008

    • Author(s)
      Honma K, Iwao-Koizumi K, Takeshita F, Yamamoto Y, Yoshida T, Nishio K, Nagahara S, Kato K, Ochiya T.
    • Journal Title

      Nat Med 14

      Pages: 939-948

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Identification of erythropoietin-induced microRNAs in haematopoietic cells during erythroid differentiation.2008

    • Author(s)
      Kosaka N, Sugiura K, Yamamoto Y, Yoshioka Y, Miyazaki H, Komatsu N, Ochiya T, Kato T.
    • Journal Title

      Br J Haematol 142

      Pages: 293-300

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] IFATS collection: in vivo therapeutic potential of human adipose tissue mesenchymal stem cells after transplantation into mice with liver injury2008

    • Author(s)
      Banas A, Teratani T, Yamamoto Y, Tokuhara M, Takeshita F, Osaki M, Kawamata M, Kato T, Okochi H, Ochiya T
    • Journal Title

      Stem Cells 26

      Pages: 2705-2712

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Down regulation of BRCA2 causes radio-sensitization of human tumor cells in vitro and in vivo2008

    • Author(s)
      Yu D, Sekine E, Fujimori A, Ochiya T, Okayasu R
    • Journal Title

      Cancer Sci 99

      Pages: 810-815

    • NAID

      10024005276

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] MicroRNAs as biomarkers and therapeutic drugs in human cancer.2008

    • Author(s)
      Osaki M, Takeshita F, Ochiya T.
    • Journal Title

      Biomarkers 13

      Pages: 658-670

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] A comparative analysis of the transcriptome and signal pathways in hepatic differentiation of human adipose mesenchymal stem cells2008

    • Author(s)
      Yamamoto Y, Banas A, Murata S, Ishikawa M, Lim CR, Teratani T, Hatada I, Matsubara K, Kato T, Ochiya T
    • Journal Title

      FEBS J 275

      Pages: 1260-1273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Identification of erythropoietin-induced microRNAs in haematopoietic cells during erythroid differentiation2008

    • Author(s)
      Kosaka N, Sugiura K, Yamamoto Y, Yoshioka Y, Miyazaki H, Komatsu N, Ochiya T, Kato T
    • Journal Title

      Br J Haematol 142

      Pages: 293-300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] RPN2 gene confers docetaxel resistance in breast cancer2008

    • Author(s)
      Honma K, Iwao-Koizumi K, Takeshita F, Yamamoto Y, Yoshida T, Nishio K, Nagahara S, Kato K, Ochiya T
    • Journal Title

      Nat Med 14

      Pages: 939-948

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Optical imaging of RNAi-mediated silencing of cancer2008

    • Author(s)
      Ochiya T, Honma K, Takeshita F, Nagahara S
    • Journal Title

      Proc of SPIE

      Pages: 6868-6868

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Application of atelocollagen-mediated siRNA delivery for RNAi therapies2007

    • Author(s)
      Honma K, Takeshita F, Ochiya T.
    • Journal Title

      Yakugaku Zasshi 127

      Pages: 807-812

    • NAID

      110006273925

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] One Argonaute family member, Eif2c2(Ago2),is essential for development and appears not to be involved in DNA methylation2007

    • Author(s)
      Morita S, Horii T, Kimura M, Goto Y, Ochiya T, Hatada I.
    • Journal Title

      Genomics 89

      Pages: 687-696

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Type l collagen gene suppresses tumor growth and invasion of malignant human glloma cells2007

    • Author(s)
      Honma K, Miyata T, Ochiya T.
    • Journal Title

      Cancer Cell lntemational 7

      Pages: 12-12

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Atelocollagen-mediated drug discovery technolog2007

    • Author(s)
      落谷孝広
    • Journal Title

      Expert Opin Drug Dicov. 2・2

      Pages: 159-167

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Atelocollagen-mediated Drug Discovery Technology.2007

    • Author(s)
      Ochiya T, Honma K, Takeshita F, Nagahara S.
    • Journal Title

      Expert Opin. Drug Discov. 2

      Pages: 159-167

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Type I collagen gene suppresses tumor growth and invasion of malignant human glioma cells.2007

    • Author(s)
      Honma K, Miyata T, Ochiya T.
    • Journal Title

      Cancer Cell Int 7

      Pages: 12-12

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Atelocollagen-mediated drug discovery technology2007

    • Author(s)
      Ochiya T, Honma K, Takeshita F, Nagahara S.
    • Journal Title

      Expent opinion on drug discover 2

      Pages: 159-167

    • Data Source
      KAKENHI-PROJECT-17016086
  • [Journal Article] Liver cells from embryonic stem cells.2004

    • Author(s)
      落谷孝広
    • Journal Title

      Pediatric Gastroenterology 2004-Reports from the 2^<nd> World Congress of Pediatric gastroenterology, Hepatology and Nuutrition

      Pages: 187-193

    • Data Source
      KAKENHI-PROJECT-12217166
  • [Patent] がんリスクの試験方法2025

    • Inventor(s)
      坂本信一、市川智彦、田村貴明、吉岡祐亮、落谷孝広
    • Industrial Property Rights Holder
      坂本信一、市川智彦、田村貴明、吉岡祐亮、落谷孝広
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-065853
    • Filing Date
      2025
    • Data Source
      KAKENHI-PROJECT-24K02575
  • [Patent] 心筋幹/前駆細胞の作製方法及び心筋線維化抑制方法2020

    • Inventor(s)
      Prieto Vila Marta, 落谷孝広
    • Industrial Property Rights Holder
      ダヴィンチユニバーサル株式会社
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Acquisition Date
      2021
    • Overseas
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Patent] ヒト肝前駆細胞の調製方法2017

    • Inventor(s)
      山田哲正、落谷孝広、勝田毅
    • Industrial Property Rights Holder
      山田哲正、落谷孝広、勝田毅
    • Industrial Property Rights Type
      特許
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Patent] ヒト肝前駆細胞の調製方法2016

    • Inventor(s)
      落谷孝広、勝田毅
    • Industrial Property Rights Holder
      落谷孝広、勝田毅
    • Industrial Property Rights Type
      特許
    • Filing Date
      2016-10-28
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Patent] 核酸導入を促進させる方法2008

    • Inventor(s)
      落谷孝広、寺田雅昭、阿蘇雄
    • Industrial Property Rights Holder
      大日本住友製薬株式会社、株式会社高研
    • Filing Date
      2008-02-15
    • Acquisition Date
      2008-02-15
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Patent] 核酸導入を促進させる方法2008

    • Inventor(s)
      落谷 孝広、 寺田 雅昭、 阿蘇 雄
    • Industrial Property Rights Holder
      大日本住友製薬株式会社、株式会社高研
    • Acquisition Date
      2008-02-15
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Patent] 核酸導入促進剤2004

    • Inventor(s)
      落谷 孝広ほか
    • Industrial Property Rights Holder
      住友製薬株式会社
    • Filing Date
      2004-11-15
    • Data Source
      KAKENHI-PROJECT-12217166
  • [Presentation] Adult cardiomyocytes-derived EVs for the treatment of cardiac fibrosis2022

    • Author(s)
      Prieto-Vila M., Muranaka A., Ochiya T.
    • Organizer
      第7回血管生物若手研究会
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Presentation] Chemically modified myocytes-derived EVs for the treatment of cardiac fibrosis.2021

    • Author(s)
      Prieto-Vila M., Muranaka A., Ochiya T.
    • Organizer
      International Society for Extracellular Vesicles
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Presentation] Improvement of cardiac fibrosis by the use of chemically modified myocytes-derived EVs.2021

    • Author(s)
      Prieto-Vila M., Muranaka A., Ochiya T.
    • Organizer
      Cardiovascular and Metabolic Week
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Presentation] 化合物刺激された心筋細胞由来エクソソームの心筋線維症に対する治療効果の検討。2021

    • Author(s)
      Prieto-Vila M., Muranaka A., Ochiya T.
    • Organizer
      Annual meeting for the Japanese Society for Extracellular Vesicles
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Presentation] Single-cell analysis reveals a small subpopulation of breast cancer cells with metastatic features within primary tumors.2021

    • Author(s)
      Prieto-Vila M., Nakayama J., Usuba W., Kojima Y., Yoshida M., Ochiya T., Yamamoto Y.
    • Organizer
      the 80th Annual meeting for the Japanese Cancer Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20F20112
  • [Presentation] 前立腺がん骨転移微小環境における成熟破骨細胞由来細胞外小胞の役割の探求2021

    • Author(s)
      田村貴明、市川智彦、落谷孝広
    • Organizer
      第31回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-20K09555
  • [Presentation] 成熟肝細胞からの肝前駆細胞誘導とその再生医療への応用可能性2017

    • Author(s)
      勝田毅、川又理樹、萩原啓太郎、高橋陵宇、山本雄介、保坂和徳、落谷孝広
    • Organizer
      第136 回日本薬理学会関東部会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Presentation] In vitro reprogramming of mature hepatocytes to culturable liver progenitor cells using small molecules2017

    • Author(s)
      Takeshi Katsuda, Masaki Kawamata, Keitaro Hagiwara, Ryou-u Takahashi, Yusuke Yamamoto, Kazunori Hosaka, Takahiro Ochiya
    • Organizer
      第15回幹細胞シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K16643
  • [Presentation] miR-135b is a key regulator of malignancy of human myxoid liposarcoma2017

    • Author(s)
      Nezu Y, Kawai A, Saito T, Ochiya T.
    • Organizer
      Orthopaedic Research Society (ORS) Annual Meeting
    • Place of Presentation
      San Diego(USA)
    • Year and Date
      2017-03-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] Round cell-specific microRNA contributes to malignancy and morphological change in myxoid liposarcoma2016

    • Author(s)
      Nezu Y, Hagiwara K, Fujiwara T, Kawai K, Matsuo K, Saito T, Ochiya T.
    • Organizer
      Research Society 2016 Annual Meeting Orland
    • Place of Presentation
      フロリダ(アメリカ)
    • Year and Date
      2016-03-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] DENTIFICATION OF TUMOR-DERIVED CIRCULATING MICRORNA SIGNATURES IN OSTEOSARCOMA PATIENTS2015

    • Author(s)
      Fujiwara T, Uotani K, Morita T, Yoshida A, Uehara T, Takeda K, Kunisada T, Ochiya T, and Ozaki T.
    • Organizer
      Connective Tissue Oncology Society
    • Place of Presentation
      ソルトレイクシティ(アメリカ)
    • Year and Date
      2015-11-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 日本発新規microRNA阻害核酸製剤Synthetic Tough Decoyを用いた骨肉腫に対する前臨床的検討.2015

    • Author(s)
      藤原智洋, 根津 悠, 吉田 晶, 魚谷弘二, 武田 健, 国定俊之, 伊庭英夫, 伊藤 博, 尾﨑敏文, 落谷孝広, 川井 章.
    • Organizer
      第88回日本整形外科学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 骨肉腫患者血清における分泌型miRNAの特定と新規バイオマーカーとしての前臨床的検討2015

    • Author(s)
      藤原智洋, 魚谷弘二, 吉田 晶, 武田 健, 国定俊之, 根津 悠, 川井 章, 落谷孝広, 尾﨑敏文
    • Organizer
      第30回日本整形外科学会基礎学術集会
    • Place of Presentation
      富山国際会議場(富山県)
    • Year and Date
      2015-10-22
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] microRNA-133aとその標的遺伝子は骨肉腫がん幹細胞分画の悪性形質を制御し骨肉腫患者の新規予後因子として機能する2015

    • Author(s)
      藤原智洋, 小坂展慶, 高橋陵宇, 竹下文隆, 吉田朗彦, 窪田大介, 小林英介, 落谷孝広, 川井 章, 尾﨑敏文.
    • Organizer
      第88回日本整形外科学会学術集会
    • Place of Presentation
      神戸国際会議場(兵庫県)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 希少がんの基礎研究2015

    • Author(s)
      落谷孝広
    • Organizer
      第1回国産がん研究シンポジウム「希少がん&#12316;望ましい医療・研究体制&#12316;」
    • Place of Presentation
      東京
    • Year and Date
      2015-02-13
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 検出・診断・治療の最前線 “miRNA診断2015

    • Author(s)
      落谷孝広
    • Organizer
      第1回COINS国際シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2015-02-27
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] RPN2は骨肉腫の様々な悪性形質を制御し新規予後因子として機能する2015

    • Author(s)
      藤原智洋, 川井 章, 落谷孝広, 尾﨑敏文.
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 粘液型脂肪肉腫の円形細胞成分に由来するmicroRNAおよび標的遺伝子の同定と悪性化形質に関与する分子メカニズムの解明2015

    • Author(s)
      根津 悠, 萩原啓太郎, 藤原智洋, 川井 章, 川端佑介, 松尾光祐, 齋藤知行, 落谷孝広.
    • Organizer
      第48回日本整形外科学会骨・軟部腫瘍学術集会
    • Place of Presentation
      かがわ国際会議場(香川)
    • Year and Date
      2015-07-09
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 人からmicroRNAを応用し、小児の骨肉腫を治す2015

    • Author(s)
      藤原智洋, 落谷孝広
    • Organizer
      第36回動物臨床医学会記念年次大会
    • Place of Presentation
      大阪国際会議場(大阪)
    • Year and Date
      2015-11-20
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 創薬研究に於ける動物治療モデルの意義と核酸・再生医療への応用2014

    • Author(s)
      落谷孝広
    • Organizer
      第35回動物臨床医学会記念年次大会
    • Place of Presentation
      大阪
    • Year and Date
      2014-11-16
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 我が国の革新的がん診断・治療技術の最前線2014

    • Author(s)
      落谷孝広
    • Organizer
      For the Better Forum 2014
    • Place of Presentation
      東京
    • Year and Date
      2014-11-12
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] エクソソームやmiRNAをターゲットとしたがん治療戦略2014

    • Author(s)
      落谷孝広
    • Organizer
      第1回緩和医療薬学研究会
    • Place of Presentation
      神奈川, 湯河原
    • Year and Date
      2014-08-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] Novel RNAi agent can control HCV replication2014

    • Author(s)
      Yoshiki Murakami, Saori Itami, Takayuki Mizutani, Masahiko Kuroda, Takahiro Ochiya, Nobuyuki Kato, Yutaka Eguchi, Hiroshi Suzuki
    • Organizer
      Keystone Symposia, “RNA Silencing”
    • Place of Presentation
      Seattle, Washington USA
    • Data Source
      KAKENHI-PROJECT-25640090
  • [Presentation] マイクロRNAによるがんの革新的診断と治療2014

    • Author(s)
      落谷孝広
    • Organizer
      メディバイオ事業研究会 第7回講演会
    • Place of Presentation
      山口 ,宇部
    • Year and Date
      2014-11-18
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] がん細胞が分泌する新規体液診断マーカー:エクソソーム2014

    • Author(s)
      落谷孝広
    • Organizer
      第34回日本分子腫瘍マーカー研究会
    • Place of Presentation
      神奈川, 横浜
    • Year and Date
      2014-09-24
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] Exosomes as a Novel Diagnostic and Therapeutic Tool for Cancer.2013

    • Author(s)
      Ochiya, T
    • Organizer
      World CTC
    • Place of Presentation
      Berlin, Deutschland
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] 分子がん転移研究の新たなる潮流:エクソソームによる前転移ニッシェの実態解明2013

    • Author(s)
      落谷 孝広
    • Organizer
      第22回 日本がん転移学会学術集会・総会
    • Place of Presentation
      長野県・松本市・ホテルブエナビスタ
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] マクロファージ細胞を用いた新規 small RNA デリバリーモデルの構築への試み2013

    • Author(s)
      石原えりか、竹下文隆、小坂展慶、高橋陵宇、藏元達谷、塩谷文章、嶋本顕、落谷孝広、田原栄俊
    • Organizer
      第36回分子生物学会年会
    • Place of Presentation
      神戸国際展示場
    • Data Source
      KAKENHI-PROJECT-24650645
  • [Presentation] 骨肉腫の肺前転移ニッシェ形成における腫瘍由来エクソソームの役割の解明2013

    • Author(s)
      落谷 孝広
    • Organizer
      第5回 日本RNAi研究会
    • Place of Presentation
      広島県・広島市・グランドプリンスホテル広島
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] マクロファージ細胞を用いた新規small RNAデリバリーモデルの構築への試み2013

    • Author(s)
      石原えりか、竹下文隆、小坂展慶、高橋陵宇、藏元達谷、塩谷文章、嶋本顕、落谷孝広、田原栄俊
    • Organizer
      第36回分子生物学会年会
    • Place of Presentation
      神戸国際展示場
    • Year and Date
      2013-12-05
    • Data Source
      KAKENHI-PROJECT-24650645
  • [Presentation] 遺伝子導入技術に基づく分子イメージング2013

    • Author(s)
      落谷 孝広
    • Organizer
      第29回  日本DDS学会学術集会
    • Place of Presentation
      京都府・京都・京都テルサ
    • Invited
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] Exosome as a novel regulator of tumor microenvironment2012

    • Author(s)
      Ochiya T
    • Organizer
      The International Center Microenvironment Society
    • Place of Presentation
      China
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] Micromanaging cancer stem cells by targeting ribophorin II(リボフォリン2を標的としたがん幹細胞のマイクロマネージメント)2012

    • Author(s)
      落谷孝広
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] Role of aging associated exosomes in vitro and in vivo2012

    • Author(s)
      Ayumi Nakamura, Megumi Okada, Nobuyuki Kosaka, Takahiro Ochiya and Hidetoshi Tahara.
    • Organizer
      ISEV meeting 2012
    • Place of Presentation
      Conference Center Wallenberg(スウェーデン)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650645
  • [Presentation] RPN2as a novel therapeutic target of cancer stem cells2012

    • Author(s)
      Ochiya T
    • Organizer
      6th World Circulating Tumour Cells Summit Asia 2012
    • Place of Presentation
      Singapore
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] Role of aging associated exosomes in vitro and in vivo2012

    • Author(s)
      Ayumi Nakamura, Megumi Okada, Nobuyuki Kosaka, Takahiro Ochiya and Hidetoshi Tahara.
    • Organizer
      ISEV meeting 2012
    • Place of Presentation
      Conference Center Wallenberg(スウェーデン)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] microRNAによる抗がん剤抵抗性の制御とがん幹細胞治療2012

    • Author(s)
      落谷孝広
    • Organizer
      第55回日本放射線影響学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] 老化関連microRNAによる膵臓がんの増殖抑制2012

    • Author(s)
      福永早央里、石原えりか、佐々木康介、竹下文隆、嶋本顕、落谷孝広、田原栄俊
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      さっぽろ芸文館
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] Role of aging associated exosomes in vitro and in vivo2012

    • Author(s)
      Ayumi Nakamura, Megumi Okada, Nobuyuki Kosaka, Takahiro Ochiya and Hidetoshi Tahara
    • Organizer
      ISEV meeting 2012
    • Place of Presentation
      Conference Center Wallenberg(スウェーデン)
    • Year and Date
      2012-04-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-24650645
  • [Presentation] Exosomal transfer of microRNA as a novel intracellular communication tool2012

    • Author(s)
      Ochiya T
    • Organizer
      22nd Meeting of the European Neurological Society Prague, Czech Republic
    • Place of Presentation
      Czech Republic(Prague)
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] 胆汁輸送機構を配備した肝暇様組織のin vitro再構築2011

    • Author(s)
      勝田毅, 小島伸彦, 落谷孝広, 酒井康行
    • Organizer
      第10回日本再生医療学会
    • Place of Presentation
      東京
    • Year and Date
      2011-03-02
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Presentation] 細胞老化を調節する新規老化関連マイクロRNAの探索と機能解析2011

    • Author(s)
      福永早央里, 徐丹, 竹下文隆, 日野由美子, 工藤保誠, 玉置彩, 石原えりか, 松永純子, 高橋陵宇, 高田隆, 嶋本顕, 落谷孝広, 田原栄俊
    • Organizer
      第3回日本RNAi研究会
    • Place of Presentation
      グランドプリンスホテル広島
    • Year and Date
      2011-08-26
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] Visualization of senescence secreted exosome2011

    • Author(s)
      岡田恵、中村亜由美、小坂展慶、落谷孝広、田原栄俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] 胆管ネットワーク構造を配備した肝臓様組織のin vitro再構築2011

    • Author(s)
      Katsuda T, Kojima N, Ochiya T, Sakai Y
    • Organizer
      第84回生化学会大会
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Presentation] 胆汁輸送機構を配備した肝臓様組織のin vitro再構築2011

    • Author(s)
      勝田 毅、小島 伸彦、落谷 孝広、酒井康行
    • Organizer
      第10回日本再生医療学会
    • Place of Presentation
      東京
    • Year and Date
      2011-03-02
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Presentation] Senescent associated microRNAs analysis in exosomes2011

    • Author(s)
      Ayumi Nakamura, Nobuyoshi Kosaka, Aya Tamaki, Megumi Okada, Takahiro Ochiya, Hidetoshi Tahara
    • Organizer
      Exosome and Microvesice
    • Place of Presentation
      Orland, USA
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] MicroRNA profiling in senescent associated exosome2011

    • Author(s)
      中村亜由美、岡田恵、小坂展慶、落谷孝広、田原栄俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] In vitro reconstruction of a liver-liketissue possessing a bile transport system,T2011

    • Author(s)
      Katsuda T,Kojima N,Ochiya T,Sakai Y,
    • Organizer
      ERMIS-EU meeting
    • Place of Presentation
      Granada,Spain
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Presentation] Micro RNA profiling in senescent associated exosome2011

    • Author(s)
      中村亜由美、岡田恵、小坂展慶、落谷孝広、田原栄俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-24
    • Data Source
      KAKENHI-PROJECT-23650626
  • [Presentation] Senescent associated microRNAs analysis inexosomes2011

    • Author(s)
      Ayumi Nakamura, Nobuyoshi Kosaka, Aya Tamaki, Megumi Okada, TakahiroOchiya, Hidetoshi Tahara
    • Organizer
      Exosome and Microvesice
    • Place of Presentation
      Orland, USA
    • Year and Date
      2011-10-16
    • Data Source
      KAKENHI-PROJECT-23650626
  • [Presentation] The potential of senescence-associated miRNAs as tumor suppressor2011

    • Author(s)
      Saori Fukunaga, Dan Xu, Fumitaka Takeshita, Yumiko Hino, Yasusei Kudo, Aya Tamaki, Erika Ishihara, Junko Matsunaga, Ryou-u Takahashi, Takashi Takata, Akira Shimamoto, Takahiro Ochiya, Hidetoshi Tahara
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-23300363
  • [Presentation] Visualization of senescence secreted exosome.2011

    • Author(s)
      岡田恵、中村亜由美、小坂展慶、落谷孝広、田原栄俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23650626
  • [Presentation] MicroRNA profiling in senescent associated exosome2011

    • Author(s)
      中村亜由美、岡田恵、小坂展慶、落谷孝広、田原栄俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-14
    • Data Source
      KAKENHI-PROJECT-23650626
  • [Presentation] 胆管ネットワーク構造を配備した肝臓様組織のin vitro再構築2011

    • Author(s)
      Katsuda T,Kojima N,Ochiya T,Sakai Y
    • Organizer
      第84回生化学会大会,
    • Place of Presentation
      京都.
    • Year and Date
      2011-09-21
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Presentation] In vitro reconstruction of a liver-like tissue possessing a bile transport system2011

    • Author(s)
      Katsuda T, Kojima N, Ochiya T, Sakai Y
    • Organizer
      TERMIS-EU meeting
    • Place of Presentation
      Granada, Spain
    • Year and Date
      2011-06-09
    • Data Source
      KAKENHI-PROJECT-22650108
  • [Presentation] Visualization of senescence secreted exosome2011

    • Author(s)
      岡田恵、中村亜由美、小坂展慶、落谷孝広、田原栄俊
    • Organizer
      第34回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2011-12-15
    • Data Source
      KAKENHI-PROJECT-23650626
  • [Presentation] microRNAによるがんの診断治療2009

    • Author(s)
      落谷孝広
    • Organizer
      第1回日本RNAi研究会
    • Place of Presentation
      広島大学
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] micro RNA as a Novel Modality for Cancer Therapy2009

    • Author(s)
      落谷孝広
    • Organizer
      第2回DKFZ-NCC Workshop on Cancer Research Tokyo
    • Place of Presentation
      がんセンター研究所
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] CRS (Colltrolled Release Society). Oligonucleotides delivery2009

    • Author(s)
      Ochiya T, Takeshita F.
    • Organizer
      36^<TH> ANNUAL MEETING AND EXPOSITION OF THE CONTROLLED RELEASE SOCIETY
    • Place of Presentation
      Copenhagen, Denmark.
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Therapeutic potential of microRNA against cancer.2009

    • Author(s)
      Ochiya T, Takeshita F.
    • Organizer
      MicroRNAi-meeting.
    • Place of Presentation
      RNAi World Congress Boston, USA.
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RPN2による糖鎖修飾を介した薬剤耐性、浸潤転移の制御機構2009

    • Author(s)
      落谷孝広
    • Organizer
      第82回日本生化学会学会(/講演)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] マイクロRNAによるがんの診断と治療2009

    • Author(s)
      落谷孝広
    • Organizer
      第68回日本癌学会学術総会(がんにおけるmicroRNA制御異常シンポジウム/講演)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RPN2 as a novel therapeutic target for cancer drug resistance.2009

    • Author(s)
      Ochiya T.
    • Organizer
      9th Jenner Glycobiology and Medicine Symposium
    • Place of Presentation
      Brussels, Belgium.
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] 核酸デリバリーが拓くnon-coding small RNAによる疾患解明2009

    • Author(s)
      落谷孝広
    • Organizer
      遺伝子・デリバリー研究会第9回シンポジウム
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] microRNAによる Cancer Stem Cell Therapy の可能性2009

    • Author(s)
      落谷孝広
    • Organizer
      第32回日本分子生物学会(/講演)
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] CRS (Controlled Release Society).2009

    • Author(s)
      Ochiya T, Takeshita F.
    • Organizer
      Oligonucleotides delivery 36THANNUAL MEETING AND EXPOSITION OF THE CONTROLLED RELEASE SOCIETY
    • Place of Presentation
      Copenhagen, Denmark.
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RNAi-based oligonucleotides therapy2009

    • Author(s)
      落谷孝広
    • Organizer
      Kashiwa Symposium on Cancer Biology 2009
    • Place of Presentation
      がんセンター東病院
    • Year and Date
      2009-11-13
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] 幹細胞の持つ肝細胞分化能と肝疾患治療RNAiによるがんの予防・診断・治療(シンポジウム)2008

    • Author(s)
      落谷孝広
    • Organizer
      第36回薬物活性シンポジウム
    • Place of Presentation
      徳島
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] MicroRNAs AS THERAPEUTIC TARGETS:POTENTIAL EFFECT ON PROSTATE CANCER MANAGEMENT.2008

    • Author(s)
      Takahiro Ochiya
    • Organizer
      第14回日本遺伝子治療学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Detection of lung meastasis-related microRNA in human osteosarcoma cell.2008

    • Author(s)
      Mitsuhiko Osaki, Fumitaka Takeshita, Hisao Ito, Mitsuo Oshimura, Takahiro Ochiya.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Identification of MicroRNAs Involved in Drug Resistance in Human Breast Cancer Cell Lines.2008

    • Author(s)
      Fumitaka Takeshita, Yusuke Yamamoto, Kaho Minoura, Ryou-u Takahashi, Nobuyuki Kosaka, Kimi Honma, Takahiro Ochiya.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] ヒト乳がん細胞株における薬剤抵抗性に関与するmiRNAの同定.2008

    • Author(s)
      高橋陵宇, 竹下文隆, 山本雄介, 箕浦加穂, 田谷敏貴, 小坂展慶, 落谷孝広.
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Optical imaging of RNAi-mediated silencing of cancer.2008

    • Author(s)
      Ochiya T, Honma K, takeshita F, Nagahara S.
    • Organizer
      Progress in Biomedical Optics and Imaging - SPIE 2008
    • Place of Presentation
      San Jose, CA, USA
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RNAi-based therapeutics against cancer.2008

    • Author(s)
      Ochiya T.
    • Organizer
      RNAi World Congress 2008
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] ヒト骨肉腫細胞における肺転移関連マイクロRNAの検出.2008

    • Author(s)
      尾崎充彦, 竹下文隆, 小坂展慶, 井藤久雄, 押村光雄, 落谷孝広.
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Development of a mouse model for suppression of peritoneal metastasis for diffuse-type gastric cancer.2008

    • Author(s)
      Takeshi Fujita, Fumitaka Takeshita, Kazuyoshi Yanagihara, Hiroyuki Ohta, Tomoko Mabuchi, Kazuhiko Aoyagi, Takeo Fukagawa, Hitoshi Katai, Takeshi Sano, Takahiro Ochiya, Teruhiko Yoshida, Hiroki Sasaki.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] The inhibition of human prostate cancer cells on bone-metastatic site by treatment with miR-16.2008

    • Author(s)
      Ryou-u Takahashi, Fumitaka Takeshita, Takahiro Ochiya.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Therapeutic potential of microRNA against cancer.2008

    • Author(s)
      Ochiya T.
    • Organizer
      The Right RNAi Meeting
    • Place of Presentation
      Brussels, Belgium
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] MicroRNAs AS THERAPEUTIC TARGETS: POTENTIAL EFFECT ON PROSTATE CANCER MANAGEMENT.2008

    • Author(s)
      Takahiro Ochiya.
    • Organizer
      第14回日本遺伝子治療学会総会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RNAi-mediated silencing of cancer.2008

    • Author(s)
      Takahiro Ochiya.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RNAi-based therapeutics against cancer.2008

    • Author(s)
      Ochiya T.
    • Organizer
      RNAi World Congress
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Potential of miRNA as cancer diagnosis and a target for therapy.2008

    • Author(s)
      Takahiro Ochiya.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Identification and characterization of a novel tumor suppressor gene on chromosome arm 18q in human pancreatic cancer.2008

    • Author(s)
      Satoru Yokoyama, Fuyuhiko Motoi, Hideo Ohtsuka, Masaharu Ishida, Nobukazu Tsukamoto, Naoyuki Kaneko, Shinichi Egawa, Michiaki Unno, Toru Furukawa, Makoto Sunamura, Takahiro Ochiya, Akira Horii.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Highly efficient microRNA delivery to tumor metastasis.2008

    • Author(s)
      Takahiro Ochiya.
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] siRNAによる放射線感受性増強(シンポジウム)2007

    • Author(s)
      落谷 孝広
    • Organizer
      第37回放射線による制癌シンポジウム
    • Place of Presentation
      つくば
    • Year and Date
      2007-07-20
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] 薬剤抵抗性獲得に関与するmicroRNAの探索2007

    • Author(s)
      外岩戸 尚美、竹下 文隆、山本 雄介、箕浦 加穂、田谷 敏貴、本間 紀美、落谷 孝広
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RPN2 gene confers docetaxel resistance in breast cancer2007

    • Author(s)
      Kimi Honma, Kyoko Iwao-Koizumi, Fumitaka Takeshita, Yusuke Yamamoto, Teruhiko Yoshida, Kasuto Nishio, Shunji Nagahara, Kikuya Kato, Takahiro Ochiya.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] 合成microRNA導入によるヒト転移性前立腺がん細胞における機能解析2007

    • Author(s)
      竹下 文隆、外岩戸 尚美、本間 紀美、落谷 孝広
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] マウス肝臓発生と肝がん形成に関わるmicroRNAの同定2007

    • Author(s)
      山本 雄介、田中 稔、宮島 篤、小泉 史明、金井 弥栄、加藤 尚志、落谷 孝広
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] RNA干渉による発がんの分子標的の同定と治療への応用(シンポジウム)2007

    • Author(s)
      落谷 孝広
    • Organizer
      第30回日本分子生物学会年会・第80回日本生花学会大会合同大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] MicroRNA therapy against bone metastasis of prostate cancer2007

    • Author(s)
      Naomi Hokaiwado, Fumitaka Takeshita, Takahiro Ochiya.
    • Organizer
      第66回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] Roles of non-coding RNAs in cancer development(including miRNAs)

    • Author(s)
      落谷孝広
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] 分子がん転移研究の新たなる潮流 : エクソソームによる前転移ニッシェの実態解明

    • Author(s)
      落谷孝広
    • Organizer
      第22回日本がん転移学会学術集会・総会
    • Place of Presentation
      長野
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] mivroRNA による抗がん剤抵抗性の制御とがん幹細胞治療

    • Author(s)
      落谷孝広
    • Organizer
      第55回日本放射線影響学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] エクソソームによる新しいシグナル伝達機構の解明

    • Author(s)
      落谷孝広
    • Organizer
      第79回日本インターフェロン・サイトカイン学会学術集会
    • Place of Presentation
      北海道, 札幌
    • Year and Date
      2014-06-19 – 2014-06-20
    • Data Source
      KAKENHI-PROJECT-26293342
  • [Presentation] 遺伝子導入技術に基づく分子イメージング

    • Author(s)
      落谷孝広
    • Organizer
      第29回日本DDS 学会学術集会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] miR-122 に対するiMIR はC 型肝炎ウイルス複製抑制に効果的である

    • Author(s)
      伊丹沙織、村上善基、黒田雅彦、落谷孝広、恵口豊、河田則文
    • Organizer
      第72回日本癌学会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25640090
  • [Presentation] 骨肉腫の肺前転移ニッシェ形成における腫瘍由来エクソソームの役割の解明

    • Author(s)
      落谷孝広
    • Organizer
      第5回日本RNAi 研究会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] Exosomes as a Novel Diagnostic and Therapeutic Tool for Cancer

    • Author(s)
      Ochiya, T
    • Organizer
      World CTC
    • Place of Presentation
      April Berlin Deutschland
    • Data Source
      KAKENHI-PROJECT-22390296
  • [Presentation] Global expression profiling of miRNA in liver development.

    • Author(s)
      Yamamoto Y, Ochiya T.
    • Organizer
      FASEB Summer Research Conference
    • Place of Presentation
      Colorado, USA
    • Data Source
      KAKENHI-PROJECT-17016086
  • [Presentation] mivroRNAによる抗がん剤抵抗性の制御とがん幹細胞治療

    • Author(s)
      落谷孝広
    • Organizer
      第55回日本放射線影響学会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-22390296
  • 1.  MATSUBARA Kenichi (20037394)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 2.  ICHIKAWA Hitoshi (30201924)
    # of Collaborated Projects: 3 results
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  • 28.  吉岡 祐亮 (60721503)
    # of Collaborated Projects: 2 results
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  • 38.  SHIMASAKI Takeo (50377420)
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  • 45.  Fukuda Shoji (70362069)
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  • 48.  小林 健一 (70019933)
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  • 49.  下遠野 邦忠 (10000259)
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  • 50.  鳥山 弘靖 (70156537)
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  • 107.  SAKAMOTO Naoya
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  • 108.  KOBAYASHI Tetsu
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  • 109.  TAGUCHI Osamu
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  • 110.  小林 和人
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  • 111.  後藤 典子
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  • 112.  GABAZZA Esteban
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    # of Collaborated Products: 1 results

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