Kawakami Eiryo 川上英良

Researcher Number	30725338
Other IDs
Affiliation (Current)	2019: 千葉大学, 大学院医学研究院, 教授 2019: 国立研究開発法人理化学研究所, 科技ハブ産連本部, ユニットリーダー
Affiliation (based on the past Project Information) *help	2019: 国立研究開発法人理化学研究所, 科技ハブ産連本部, ユニットリーダー 2017 – 2018: 国立研究開発法人理化学研究所, 科学技術ハブ推進本部, ユニットリーダー 2016 – 2017: 国立研究開発法人理化学研究所, 科学技術ハブ推進本部, 上級研究員 2015: 国立研究開発法人理化学研究所, その他部局等, 研究員 2015: 国立研究開発法人理化学研究所, 統合生命医科学研究センター, 特別研究員
Review Section/Research Field	Principal Investigator Dermatology / System genome science / Complex Systems Disease Theory Except Principal Investigator Complex systems / Constructive Systems Biology / Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator マイクロRNA / 遺伝子制御ネットワーク / 状態遷移モデル / 転写因子 / 疾患予測 / 多階層ネットワーク / 分岐現象 / Gene set enrichment解析 / 制御ネットワーク / 機械学習 … More Except Principal Investigator マイクロRNA / HLA遺伝子 / バイオマーカー / 人工股関節全置換術 / 人工知能 / ゲノム / 人工共培養系 / ビッグデータ / 進化のダイナミクス / 遺伝統計学 / 機械学習 / インプラント設置 / 人工培養系 / 数理モデル / 横断的オミクス解析 / 複合オミクス解析 / バイオインフォマティクス / HLA imputation法 Less

人工知能を用いた人工股関節全置換術における最適なインプラント設置に関する研究Ongoing
- Principal Investigator
  
  稲葉裕
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Yokohama City University
生命システムの破綻にひそむ秩序を解明するPrincipal InvestigatorOngoing
- Principal Investigator
  
  川上英良
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Complex Systems Disease Theory
- Research Institution
  Institute of Physical and Chemical Research
Experimental evolution of Saccharomyces cerevisiae
- Principal Investigator
  
  Nakaoka Shinji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Constructive Systems Biology
- Research Institution
  The University of Tokyo
Comprehensive identification of microRNAs that control atopic dermatitis using a gene regulatory networkPrincipal Investigator
- Principal Investigator
  
  Kawakami Eiryo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  System genome science
  Dermatology
- Research Institution
  Institute of Physical and Chemical Research
遺伝統計学とビッグデータの邂逅がもたらす新たながんゲノム創薬Ongoing
- Principal Investigator
  
  岡田随象
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Osaka University
  Tokyo Medical and Dental University

All 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] 実験医学増刊2017
- Author(s)
  川上英良、大田達郎
- Total Pages
  8
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-15KT0147
[Journal Article] T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate2018
- Author(s)
  Ise Wataru、Fujii Kentaro、Shiroguchi Katsuyuki、Ito Ayako、Kometani Kohei、Takeda Kiyoshi、Kawakami Eiryo、Yamashita Kazuo、Suzuki Kazuhiro、Okada Takaharu、Kurosaki Tomohiro
- Journal Title
  
  Immunity
  
  Volume: 48 Pages: 702-715
- DOI
  10.1016/j.immuni.2018.03.027
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PROJECT-17K08883
[Journal Article] Deregulated Mucosal Immune Surveillance through Gut-Associated Regulatory T Cells and PD-1(+) T Cells in Human Colorectal Cancer2018
- Author(s)
  Fujimoto Hanae、Saito Yoriko、Ohuchida Kenoki、Kawakami Eiryo、Fujiki Saera、Watanabe Takashi、Ono Rintaro、Kaneko Akiko、Takagi Shinsuke、Najima Yuho、Hijikata Atsushi、Cui Lin、Ueki Takashi、Oda Yoshinao、Hori Shohei、Ohara Osamu、Nakamura Masafumi、Saito Takashi、Ishikawa Fumihiko
- Journal Title
  
  J Immunol
  
  Volume: 200 Pages: 3291-3303
- DOI
  10.4049/jimmunol.1701222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747
[Journal Article] Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells2018
- Author(s)
  Miyai Tomohiro、Takano Junichiro、Endo Takaho A.、Kawakami Eiryo、Agata Yasutoshi、Motomura Yasutaka、Kubo Masato、Kashima Yukie、Suzuki Yutaka、Kawamoto Hiroshi、Ikawa Tomokatsu
- Journal Title
  
  Genes & Development
  
  Volume: 32 Pages: 112-126
- DOI
  10.1101/gad.309575.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196
[Journal Article] アトピー性皮膚炎のリバーストランスレーショナルリサーチ2017
- Author(s)
  川崎洋、川上英良、天谷雅行、古関明彦
- Journal Title
  
  実験医学
  
  Volume: Vol. 35 Pages: 33-39
- Data Source
  KAKENHI-PROJECT-16KT0196
[Journal Article] Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells2017
- Author(s)
  Hayatsu Norihito、Miyao Takahisa、Tachibana Masashi、Murakami Ryuichi、Kimura Akihiko、Kato Takako、Kawakami Eiryo、Endo Takaho A.、Setoguchi Ruka、Watarai Hiroshi、Nishikawa Takeshi、Yasuda Takuwa、Yoshida Hisahiro、Hori Shohei
- Journal Title
  
  Immunity
  
  Volume: 47
- DOI
  10.1016/j.immuni.2017.07.008
- Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PUBLICLY-17H05789, KAKENHI-PROJECT-15H04747, KAKENHI-PROJECT-16K14591
[Journal Article] Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling2017
- Author(s)
  Tenno Mari、Shiroguchi Katsuyuki、Muroi Sawako、Kawakami Eiryo、Koseki Keita、Kryukov Kirill、Imanishi Tadashi、Ginhoux Florent、Taniuchi Ichiro
- Journal Title
  
  J. Exp. Med
  
  Volume: 214 Pages: 2933-2946
- DOI
  10.1084/jem.20170729
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PUBLICLY-17H05805
[Journal Article] 公共ハイスループットChIPデータを用いた遺伝子制御ネットワークの構築とその活用法2017
- Author(s)
  川上英良、大田達郎
- Journal Title
  
  実験医学増刊
  
  Volume: Vol. 35 Pages: 112-118
- Data Source
  KAKENHI-PROJECT-15K21631
[Journal Article] Leading role of TBP in the Establishment of Complexity in Eukaryotic Transcription Initiation Systems.2017
- Author(s)
  Kawakami Eiryo、Adachi Naruhiko、Senda Toshiya、Horikoshi Masami
- Journal Title
  
  Cell Rep.
  
  Volume: 21 Pages: 3941-3956
- DOI
  10.1016/j.celrep.2017.12.034
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16KT0196, KAKENHI-PROJECT-17K07321, KAKENHI-PROJECT-17H06264, KAKENHI-PROJECT-15KT0147
[Journal Article] Significant impact of miRNA-target gene networks on genetics of human complex traits2016
- Author(s)
  Okada Y, Muramatsu T, Suita N, Kanai M, Kawakami E et al.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 22223-22223
- DOI
  10.1038/srep22223
- Open Access / Acknowledgement Compliant / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K14429, KAKENHI-PROJECT-15K21631, KAKENHI-PLANNED-15H05908, KAKENHI-PLANNED-15H05911, KAKENHI-PROJECT-25250019, KAKENHI-PROJECT-15H05670
[Journal Article] Weighted Enrichment Method for Prediction of Transcription Regulators from Transcriptome and Global Chromatin Immunoprecipitation data2016
- Author(s)
  Eiryo Kawakami, Shinji Nakaoka, Tazro Ohta and Hiroaki Kitano
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 印刷中 Pages: 5010-5021
- DOI
  10.1093/nar/gkw355
- Open Access / Acknowledgement Compliant / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21631, KAKENHI-PROJECT-15KT0147, KAKENHI-PROJECT-16KT0196
[Journal Article] Network analyses based on comprehensive molecular interaction maps reveal robust control structures in yeast stress response pathways.2016
- Author(s)
  Eiryo Kawakami, Vivek K Singh, Kazuko Matsubara, Takashi Ishii, Yukiko Matsuoka, Takeshi Hase,Priya Kulkarni, Kenaz Siddiqui, Janhavi Kodilkar, Nitisha Danve, Indhupriya Subramanian, Manami Katoh, Yuki Shimizu-Yoshida, Samik Ghosh, Abhay Jere & Hiroaki Kitano
- Journal Title
  
  npj Systems Biology and Applications
  
  Volume: 2 Pages: 15018-15018
- DOI
  10.1038/npjsba.2015.18
- Open Access / Int'l Joint Research / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15KT0147, KAKENHI-PROJECT-15K21631, KAKENHI-ORGANIZER-22136001
[Presentation] 機械学習・数理科学で疾患の多様性と個別性に迫る2018
- Author(s)
  川上英良
- Organizer
  Society 5.0時代のヘルスケアの在り方
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] Dynamic transition of the human skin microbial patterns associated with atopic dermatitis pathology2018
- Author(s)
  Eiryo Kawakami, Hiroshi Kawasaki, Shoko Obata, Aki Honda, Naoko Mochimaru, Ayano Fukushima, Fumiyo Yasuda-Sekiguchi, Takashi Sasaki, Wataru Suda, Kenya Honda, Tamotsu Ebihara, Masayuki Amagai
- Organizer
  Cell Symposia Next Gen Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] ウイルス・細菌感染における宿主転写制御2017
- Author(s)
  川上英良
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] 医学生物学研究におけるデータ駆動型アプローチ2017
- Author(s)
  川上英良
- Organizer
  第9回数理デザイン道場（CREST生命動態）
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] ウイルス・細菌感染における宿主転写制御2017
- Author(s)
  川上英良
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター（宮城県・仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] ウイルス・細菌感染における宿主転写制御2017
- Author(s)
  川上英良
- Organizer
  第90回日本細菌学会総会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K21631
[Presentation] 医学生物学研究におけるデータ駆動型アプローチ2017
- Author(s)
  川上英良
- Organizer
  京都大学ウイルス再生研第三回生命情報研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] 医学生物学研究におけるデータ駆動型アプローチ2017
- Author(s)
  川上英良
- Organizer
  第9回数理デザイン道場（CREST生命動態）
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] 生物ネットワークに潜む情報を探る：タンパク質相互作用ネットワークに基づくシグナル伝達パスウェイ網羅的再構成2016
- Author(s)
  川上英良
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K21631
[Presentation] 生物ネットワークに潜む情報を探る:タンパク質相互作用ネットワークに基づくシグナル伝達パスウェイ網羅的再構成2016
- Author(s)
  川上英良
- Organizer
  日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県・仙台市）
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] 複合体が生み出すシグナル伝達確率的ダイナミクスの制御機構2016
- Author(s)
  川上英良, 古関恵太, 中岡慎治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] 公共ChIPデータを活用した遺伝子制御ネットワーク構築と転写因子予測2016
- Author(s)
  川上英良
- Organizer
  トーゴーの日シンポジウム2016
- Place of Presentation
  東京大学（東京都・文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-15K21631
[Presentation] 公共ChIPデータを活用した遺伝子制御ネットワーク構築と転写因子予測2016
- Author(s)
  川上英良
- Organizer
  トーゴーの日シンポジウム2016
- Place of Presentation
  東京大学
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] 複合体が生み出すシグナル伝達確率的ダイナミクスの制御機構2016
- Author(s)
  川上英良, 古関恵太, 中岡慎治
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] 公共ChIPデータを活用した遺伝子制御ネットワーク構築と転写因子予測2016
- Author(s)
  川上英良
- Organizer
  トーゴーの日シンポジウム2016
- Place of Presentation
  東京大学（東京都・文京区）
- Invited
- Data Source
  KAKENHI-PROJECT-16KT0196
[Presentation] 生物ネットワークに潜む情報を探る：タンパク質相互作用ネットワークに基づくシグナル伝達パスウェイ網羅的再構成2016
- Author(s)
  川上英良
- Organizer
  日本生化学会大会
- Place of Presentation
  仙台国際センター
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] 遺伝子発現から転写制御因子を予測する確率的Gene Set Enrichment解析2015
- Author(s)
  川上英良、中岡慎治、北野宏明
- Organizer
  BMB2015 (第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-04
- Invited
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] Impaired balance between antagonistic transcriptional modules during the progression of inflammatory skin disease2015
- Author(s)
  Eiryo Kawakami, Hisahiro Yoshida, Takuwa Yasuda, Shinji Nakaoka, Hiroaki Kitano, Haruhiko Koseki
- Organizer
  Functional Genomics and Systems Biology: From Model Organisms to Human Health
- Place of Presentation
  Welcome Trust Sanger Institute（United Kingdom)
- Year and Date
  2015-10-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21631
[Presentation] Impaired balance between antagonistic transcriptional modules during the progression of inflammatory skin disease2015
- Author(s)
  Eiryo Kawakami, Hisahiro Yoshida, Takuwa Yasuda, Shinji Nakaoka, Hiroaki Kitano
- Organizer
  Functional Genomics and Systems Biology: From Model Organisms to Human Health
- Place of Presentation
  Welcome Trust Sanger Institute
- Year and Date
  2015-10-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KT0147
[Presentation] 遺伝子発現から転写制御因子を予測する確率的Gene Set Enrichment解析2015
- Author(s)
  川上英良、中岡慎治、北野宏明
- Organizer
  BMB2015 (第38回日本分子生物学会年会、第88回日本生化学会大会　合同大会）
- Place of Presentation
  神戸ポートアイランド（兵庫・神戸市）
- Year and Date
  2015-12-04
- Int'l Joint Research / Invited
- Data Source
  KAKENHI-PROJECT-15K21631

1. Nakaoka Shinji (30512040)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 細田一史 (30515565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 岡田随象 (70727411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 鎌谷洋一郎 (00720880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 浦山ケビン (60726850)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 藤本明洋 (30525853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 稲葉裕 (40336574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伊勢渉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 堀昌平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 渡会浩志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 谷内一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 稲澤譲治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 村松智輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 千田俊哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 北野宏明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawakami Eiryo 川上 英良

Research Projects

Research Products

Co-Researchers

人工知能を用いた人工股関節全置換術における最適なインプラント設置に関する研究Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生命システムの破綻にひそむ秩序を解明するPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental evolution of Saccharomyces cerevisiae

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive identification of microRNAs that control atopic dermatitis using a gene regulatory networkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

遺伝統計学とビッグデータの邂逅がもたらす新たながんゲノム創薬Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 実験医学増刊2017

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deregulated Mucosal Immune Surveillance through Gut-Associated Regulatory T Cells and PD-1(+) T Cells in Human Colorectal Cancer2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] アトピー性皮膚炎のリバーストランスレーショナルリサーチ2017

Author(s)

Journal Title

Data Source

[Journal Article] Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cbfβ2 deficiency preserves Langerhans cell precursors by lack of selective TGFβ receptor signaling2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 公共ハイスループットChIPデータを用いた 遺伝子制御ネットワークの構築と その活用法2017

Author(s)

Journal Title

Data Source

[Journal Article] Leading role of TBP in the Establishment of Complexity in Eukaryotic Transcription Initiation Systems.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significant impact of miRNA-target gene networks on genetics of human complex traits2016

Author(s)

Journal Title

Kawakami Eiryo 川上英良

[Journal Article] 公共ハイスループットChIPデータを用いた遺伝子制御ネットワークの構築とその活用法2017

[Presentation] 生物ネットワークに潜む情報を探る:タンパク質相互作用ネットワークに基づくシグナル伝達パスウェイ網羅的再構成2016