Endo Yusuke 遠藤裕介

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ENDO Yusuke 遠藤裕介

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Researcher Number	80612192
Other IDs
Affiliation (Current)	2025: 公益財団法人かずさDNA研究所, 先端研究開発部, 室長
Affiliation (based on the past Project Information) *help	2018 – 2025: 公益財団法人かずさDNA研究所, 先端研究開発部, 室長 2016 – 2017: 千葉大学, 大学院医学研究院, 特任講師 2012 – 2013: 千葉大学, 医学(系)研究科(研究院), 特任講師
Review Section/Research Field	Principal Investigator Transformative Research Areas, Section (III) / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Pathological medical chemistry / Biological Sciences / Immunology Except Principal Investigator Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 脂質代謝 / Th17 / ACC1 / RORgt / 肥満 / Th17細胞 / 自己免疫疾患 / 高度肥満 / アレルギー / Tpath2 … More / 病態医化学 / 免疫学 / 細胞内代謝 / 脂質 / リピドミクス解析 / RORγt / 脂肪滴 / 病原性T細胞 / Th17バイアス / TCRレパトア / レパトア / 自己指向性 / Treg細胞 / Acsbg1 / 慢性炎症 / 免疫疾患 / Treg / 病原性リンパ球 / CRISPR/Cas9 TGA / CRISPR-TGA / 病原性Th2細胞 / アトピー / ぜんそく / エピゲノム編集 / CRISPR/Cas9 / 細胞分化 / 核内受容体リガンド / ILC3 / T細胞分化 / 脂質リガンド / 核内受容体 / アレルギー・ぜんそく / Tpath2細胞 / ＩＬＣ２ / Ｔｐａｔｈ２ / アレルギー性皮膚炎 / ILC2 / 喘息 / 炎症性免疫疾患 / RORyt / リポクオリティ / ゲノム編集 / Eomesodermin / インターロイキン5(IL-5) / Eomesodermin（Eomes） / IL-33 / インターロイキン5（IL-5） / メモリーTh2細胞 / アレルギー性気道炎症 … More Except Principal Investigator プロテオミクス / シングルセル / AI / 小児 / 全身性エリテマトーデス / プロテオミクス解析 / 細胞の運命決定 / T細胞初期分化 / 系列決定 / 遺伝子発現制御 / 転写因子 / 細胞運命決定 / T細胞 / 転写因子ネットワーク / 発生段階特異的 / 転写制御ネットワーク / 造血幹細胞 / T前駆細胞 / Notchシグナル Less

Th17細胞の自己認識における脂質代謝の作用と病原性応答への意義解明Principal Investigator
- Principal Investigator
  
  遠藤裕介
- Project Period (FY)
  2025 – 2026
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kazusa DNA Research Institute
リンパ球系譜のRORgt多機能性を司る脂質代謝経路の解明Principal Investigator
- Principal Investigator
  
  遠藤裕介
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kazusa DNA Research Institute
Identification of pathogenic T progenitors using lipid droplet fate-mapping micePrincipal Investigator
- Principal Investigator
  
  遠藤裕介
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kazusa DNA Research Institute
T細胞が認識する肥満特有の自己指向性免疫の解明Principal Investigator
- Principal Investigator
  
  遠藤裕介
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Kazusa DNA Research Institute
Elucidation of immunogenetic features of childhood-onset SLE by referencing adult peripheral blood single-cell data using AI
- Principal Investigator
  
  宮前多佳子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokyo Women's Medical University
Development of Novel Therapy for Allergic Diseases Using the CRISPR/Cas9 TGA SystemPrincipal Investigator
- Principal Investigator
  
  Endo Yusuke
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kazusa DNA Research Institute
Identification of functional lipids that control Th17/Treg balance in an obese environmentPrincipal Investigator
- Principal Investigator
  
  ENDO YUSUKE
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kazusa DNA Research Institute
Stage-specific roles of Notch signaling on induction of T cell development from hematopoietic progenitor cells
- Principal Investigator
  
  HOSOKAWA HIROYUKI
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Tokai University
リポクオリティが制御する脂質リガンドに依存したRORγt機能多様性の解明Principal Investigator
- Principal Investigator
  
  遠藤裕介
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kazusa DNA Research Institute
炎症性Th17細胞においてRORγtが認識するリポクオリティ分子機構の解明Principal Investigator
- Principal Investigator
  
  遠藤裕介
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Chiba University
Elucidation of the mechanism of asthma condition deterioration in the obese environment and the establish of treatment developmentPrincipal Investigator
- Principal Investigator
  
  Endo Yusuke
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kazusa DNA Research Institute
  Chiba University
The regulation of memory Th2 cell-dependent allergic airway inflammation through the IL-33-T1/ST2 pathway.Principal Investigator
- Principal Investigator
  
  ENDO Yusuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Chiba University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] Chronic Inflammation Mechanisms and Regulation2016
- Author(s)
  Endo, Y., Hirahara, K., Shinoda, K., Iinuma, T., Yamamoto, H., Motohashi, S., Okamoto, Y., and Nakayama, T.
- Total Pages
  701
- Publisher
  SPRINGER NATURE
- Data Source
  KAKENHI-PROJECT-16H06224
[Book] Chronic Inflammation Mechanisms and Regulation2016
- Author(s)
  Endo, Y., Hirahara, K., Shinoda, K., Iinuma, T., Yamamoto, H., Motohashi, S., Okamoto, Y., and Nakayama, T.
- Total Pages
  701
- Publisher
  SPRINGER NATURE
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Book] T細胞の免疫記憶、免疫学Update—分子病態の解明と治療への展開—2012
- Author(s)
  遠藤裕介、中山俊憲
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24790461
[Book] 免疫学Update-分子病態の解明と治療への展開-2012
- Author(s)
  遠藤裕介、中山俊憲
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] IL-27 regulates the differentiation of follicular helper NKT cells via metabolic adaptation of mitochondria2024
- Author(s)
  Kamii Yasuhiro、Hayashizaki Koji、Kanno Toshio、Chiba Akio、Ikegami Taku、Saito Mitsuru、Akeda Yukihiro、Ohteki Toshiaki、Kubo Masato、Yoshida Kiyotsugu、Kawakami Kazuyoshi、Oishi Kazunori、Araya Jun、Kuwano Kazuyoshi、Kronenberg Mitchell、Endo Yusuke、Kinjo Yuki
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 9
- DOI
  10.1073/pnas.2313964121
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14552, KAKENHI-PROJECT-21K07085, KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-23K24382
[Journal Article] Universal pretreatment development for low-input proteomics using laury maltose Neopentyl Glycerol2024
- Author(s)
  Konno R., Ishikawa M., Nakajima D., Endo Y., Ohara O., and Kawashima Y.
- Journal Title
  
  Molecular & cellular proteomics
  
  Volume: 23 Issue: 4 Pages: 100745-100745
- DOI
  10.1016/j.mcpro.2024.100745
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-23K27158
[Journal Article] ACC1-mediated fatty acid biosynthesis intrinsically controls thymic iNKT cell development2023
- Author(s)
  Kanno Toshio、Miyako Keisuke、Endo Takeru、Yokoyama Satoru、Asou Hikari K、Yamada Kazuko、Ohara Osamu、Nakayama Toshinori、Kimura Motoko Y、Endo Yusuke
- Journal Title
  
  International Immunology
  
  Volume: 36 Issue: 3 Pages: 129-139
- DOI
  10.1093/intimm/dxad049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14552, KAKENHI-PLANNED-22H05189, KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455
[Journal Article] Lipid metabolism in Th17 cell function2023
- Author(s)
  Kanno Toshio、Nakajima Takahiro、Miyako Keisuke、Endo Yusuke
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 245 Pages: 108411-108411
- DOI
  10.1016/j.pharmthera.2023.108411
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20766, KAKENHI-PROJECT-23K14552, KAKENHI-PROJECT-22K15502, KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455
[Journal Article] Weight loss improves inflammation by Th17 cells in an obese patient with psoriasis at high risk for cardiovascular events.2023
- Author(s)
  Maezawa Y., Endo Y., Kono S., Ohno T., Nakamura Y., Teramoto N., Ysukagoshi A., Aono K., Minamizuka T., Kato H., Ishikawa T., Koshizuka M., Takemoto M., Nakayama T., and Yokote K.
- Journal Title
  
  J. Diabetes invest.
  
  Volume: 14 Issue: 9 Pages: 1136-1139
- DOI
  10.1111/jdi.14037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-19H05650
[Journal Article] Dataset for proteogenomic signature analysis of differentiation of CD4+ T cell subsets.2023
- Author(s)
  Konno R., Kanno T., Ohara O., Endo Y., and Kawashima Y.
- Journal Title
  
  Journal of Proteome Data and Methods
  
  Volume: 5 Issue: 0 Pages: 10
- DOI
  10.14889/jpdm.2023.0010
- ISSN
  2434-6454
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04794
[Journal Article] 1-Oleoyl-lysophosphatidylethanolamine stimulates RORγt activity in T <sub>H</sub> 17 cells2023
- Author(s)
  Endo Yusuke、Kanno Toshio、Nakajima Takahiro、Ikeda Kazutaka、Taketomi Yoshitaka、Yokoyama Satoru、Sasamoto Shigemi、Asou Hikari K.、Miyako Keisuke、Hasegawa Yoshinori、Kawashima Yusuke、Ohara Osamu、Murakami Makoto、Nakayama Toshinori
- Journal Title
  
  Science Immunology
  
  Volume: 8 Issue: 86
- DOI
  10.1126/sciimmunol.add4346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14552, KAKENHI-PROJECT-22K15502, KAKENHI-PROJECT-20H05691, KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-19H05650
[Journal Article] Epithelial cell-derived cytokine TSLP modulates metabolic program of regulatory T cells by enhancing fatty acid uptake to suppress the intestinal inflammation2023
- Author(s)
  Kasuya T., Tanaka S., Etori K., Shoda J., Hattori K., Endo Y., Kitajima M., Kageyama T., Iwamoto T., Yokota M., Iwata A., Suto A., Suzuki K., Suzuki H., Ziegler SF., and Nakajima H
- Journal Title
  
  Sci. Rep.
  
  Volume: 13 Issue: 1 Pages: 1653-1653
- DOI
  10.1038/s41598-023-28987-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-20K07460, KAKENHI-PROJECT-20K08797, KAKENHI-PROJECT-21K16297, KAKENHI-PROJECT-23K06590, KAKENHI-PROJECT-23K07738, KAKENHI-PROJECT-22K16353
[Journal Article] Senescence-associated inflammation and inhibition of adipogenesis in subcutaneous fat in Werner syndrome.2023
- Author(s)
  Sawada D., Kato H., Kaneko H., Kinoshita D., Funayama S., Minamizuka T., Takasaki A., Igarashi K., Koshizaka M., Watanabe T. A., Nakamura R., Aono K., Yamaguchi A., Teramoto N., Maeda Y., Ohno T., Hayashi A., Ide K., Ide S., Shoji M., Kitamoto T., Endo Y., et al.
- Journal Title
  
  Aging
  
  Volume: 15 Issue: 19 Pages: 9948-9964
- DOI
  10.18632/aging.205078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-23H04794, KAKENHI-PROJECT-20H03455
[Journal Article] Caspase-4 contributes to Site-1 protease cleavage and SREBP1 activation in the inflammatory response of macrophages.2023
- Author(s)
  Cheng Y, Manabe I, Hayakawa S, Endo Y, and Oishi Y.
- Journal Title
  
  Front Immunol
  
  Volume: 14 Pages: 1009973-1009973
- DOI
  10.3389/fimmu.2023.1009973
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19534, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-23K21625, KAKENHI-PROJECT-20H03679, KAKENHI-PROJECT-23K27603
[Journal Article] Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells2022
- Author(s)
  Koizumi Maria、Kama Yuichi、Hirano Ken-ichi、Endo Yusuke、Tanaka Tomoaki、Hozumi Katsuto、Hosokawa Hiroyuki
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 298 Issue: 11 Pages: 102506-102506
- DOI
  10.1016/j.jbc.2022.102506
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16331, KAKENHI-PROJECT-19H03692, KAKENHI-PROJECT-20H03455
[Journal Article] Fatty acid metabolism in T-cell function and differentiation2022
- Author(s)
  Endo Y., Kanno T., and Nakajima T
- Journal Title
  
  International Immunol.
  
  Volume: 34 Issue: 11 Pages: 579-579
- DOI
  10.1093/intimm/dxac025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-21K20766
[Journal Article] Characterization of proteogenomic signatures of differentiation of CD4+ T cell subsets2022
- Author(s)
  Kanno T., Konno R., Miyako K, Nakajima T., Yokoyama S., Sasamoto S., Asou HK., Ohzeki J., Kawashima Y., Hasegawa Y., Ohara O., and Endo Y
- Journal Title
  
  DNA Res.
  
  Volume: 30 Issue: 1 Pages: 1-1
- DOI
  10.1093/dnares/dsac054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-21K20766
[Journal Article] SCD2-mediated cooperative activation of IRF3-IRF9 regulatory circuit controls type I interferon transcriptome in CD4+ T cells2022
- Author(s)
  Kanno Toshio、Miyako Keisuke、Nakajima Takahiro、Yokoyama Satoru、Sasamoto Shigemi、Asou Hikari K.、Ohara Osamu、Nakayama Toshinori、Endo Yusuke
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 904875-904875
- DOI
  10.3389/fimmu.2022.904875
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-21K15476, KAKENHI-PROJECT-21K20766
[Journal Article] LMO2 is essential to maintain the ability of progenitors to differentiate into T-cell lineage in mice2021
- Author(s)
  Hirano K., Hosokawa H., Koizumi M., Endo Y., Yahata T., and Hozumi K
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.68227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21618, KAKENHI-PROJECT-19H03692, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-20K07330, KAKENHI-PROJECT-23K21386
[Journal Article] Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis2021
- Author(s)
  Kanno Toshio、Nakajima Takahiro、Kawashima Yusuke、Yokoyama Satoru、Asou Hikari K.、Sasamoto Shigemi、Hayashizaki Koji、Kinjo Yuki、Ohara Osamu、Nakayama Toshinori、Endo Yusuke
- Journal Title
  
  Cell Reports
  
  Volume: 37(6) Issue: 6 Pages: 109921-109921
- DOI
  10.1016/j.celrep.2021.109921
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21618, KAKENHI-PROJECT-19K16704, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-21K07085, KAKENHI-PROJECT-21K20766, KAKENHI-PROJECT-19H03705
[Journal Article] A simple method for In-depth proteome analysis of mammalian cell culture conditioned media containing fetal bovine serum.2021
- Author(s)
  Nakamura R., Nakajima D., Sato H., Endo Y., Ohara O., and Kawashima Y.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 5 Issue: 5 Pages: 2565-2565
- DOI
  10.3390/ijms22052565
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21618, KAKENHI-PROJECT-20H03455
[Journal Article] SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4+ T cells2021
- Author(s)
  Kanno Toshio、Nakajima Takahiro、Yokoyama Satoru、Asou Hikari K.、Sasamoto Shigemi、Kamii Yasuhiro、Hayashizaki Koji、Ouchi Yasuo、Onodera Taishi、Takahashi Yoshimasa、Ikeda Kazutaka、Hasegawa Yoshinori、Kinjo Yuki、Ohara Osamu、Nakayama Toshinori、Endo Yusuke
- Journal Title
  
  Communications Biology
  
  Volume: 4(1) Issue: 1 Pages: 820-820
- DOI
  10.1038/s42003-021-02310-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21618, KAKENHI-PROJECT-19K16704, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-21K07085, KAKENHI-PROJECT-21K15476, KAKENHI-PROJECT-19H03705, KAKENHI-PROJECT-17KK0189, KAKENHI-PROJECT-20K07651
[Journal Article] ACC1-expressing pathogenic T helper 2 cell populations facilitate lung and skin inflammation in mice2021
- Author(s)
  Nakajima Takahiro、Kanno Toshio、Yokoyama Satoru、Sasamoto Shigemi、Asou Hikari K.、Tumes Damon J.、Ohara Osamu、Nakayama Toshinori、Endo Yusuke
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 218(12) Issue: 12
- DOI
  10.1084/jem.20210639
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-20K21618, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-21K20766
[Journal Article] 「代謝で免疫を制御する」：脂肪酸代謝による記憶T細胞への運命決定2020
- Author(s)
  遠藤裕介
- Journal Title
  
  医学のあゆみ
  
  Volume: 1 Pages: 54-60
- Data Source
  KAKENHI-PROJECT-20H03455
[Journal Article] 「代謝で免疫を制御する」：脂肪酸代謝による記憶T細胞への運命決定2020
- Author(s)
  遠藤裕介
- Journal Title
  
  医学のあゆみ
  
  Volume: 1 Pages: 54-60
- Data Source
  KAKENHI-PROJECT-20K21618
[Journal Article] アレルギー疾患におけるIL-33と病原性Th2細胞2020
- Author(s)
  遠藤裕介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 5 Pages: 462-469
- Data Source
  KAKENHI-PROJECT-20H03455
[Journal Article] A long noncoding RNA regulates inflammation resolution by mouse macrophages through fatty acid oxidation activation2020
- Author(s)
  Nakayama Yukiteru、Fujiu Katsuhito、Yuki Ryuzaburo、Oishi Yumiko、Morioka Masaki Suimye、Isagawa Takayuki、Matsuda Jun、Oshima Tsukasa、Matsubara Takumi、Sugita Junichi、Kudo Fujimi、Kaneda Atsushi、Endo Yusuke、Nakayama Toshinori、Nagai Ryozo、Komuro Issei、Manabe Ichiro
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 117 Issue: 25 Pages: 14365-14375
- DOI
  10.1073/pnas.2005924117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08061, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-19K22615, KAKENHI-PROJECT-20K21618, KAKENHI-PROJECT-20K17073, KAKENHI-ORGANIZER-17H06391, KAKENHI-PUBLICLY-20H04938, KAKENHI-PUBLICLY-20H04956, KAKENHI-PROJECT-19H05650, KAKENHI-PROJECT-19H03648, KAKENHI-PROJECT-20H03455, KAKENHI-PROJECT-20H03672, KAKENHI-PROJECT-19K08542
[Journal Article] T細胞の活性化と脂質代謝2020
- Author(s)
  遠藤裕介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 5 Pages: 449-455
- Data Source
  KAKENHI-PROJECT-20H03455
[Journal Article] 脂質代謝による免疫システムのfine-tuning2020
- Author(s)
  遠藤裕介
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 2 Pages: 74-77
- Data Source
  KAKENHI-PROJECT-20H03455
[Journal Article] 脂質代謝による免疫システムのfine-tuning2020
- Author(s)
  遠藤裕介
- Journal Title
  
  感染・炎症・免疫
  
  Volume: 2 Pages: 74-77
- Data Source
  KAKENHI-PROJECT-20K21618
[Journal Article] T細胞の活性化と脂質代謝2020
- Author(s)
  遠藤裕介
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 5 Pages: 449-455
- Data Source
  KAKENHI-PROJECT-20K21618
[Journal Article] Ezh2 controls development of natural killer T cells that cause spontaneous asthema-like pathology2019
- Author(s)
  Tumes, D., Hirahara, K., Papadopoulos, M., Shinoda, K., Onodera, A., Kumagai, J., Yip, K. H., Pant, H., Kokubo, K., Kiuchi, M., Aoki, A., Obata-Ninomiya, K., Tokoyoda, K., Endo, Y., Kimura, M. Y., and Nakayama, T
- Journal Title
  
  J. Allergy Clin. Immunol
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Journal Article] ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis2019
- Author(s)
  Yusuke Endo, Atsushi Onodera, Kazushige Obata-Ninomiya, Ryo Koyama-Nasu, Hikari K. Asou, Toshihiro Ito, Takeshi Yamamoto, Toshio Kanno, Takahiro Nakajima, Kenji Ishiwata, Hirotaka Kanuka, Damon J. Tumes, Toshinori Nakayama
- Journal Title
  
  Nature Metabolism
  
  Volume: 1(2) Issue: 2 Pages: 261-275
- DOI
  10.1038/s42255-018-0025-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-18K07257
[Journal Article] Ezh2 controls development of natural killer T cells, which cause spontaneous asthma-like pathology2019
- Author(s)
  Tumes, D., Hirahara, K., Papadopoulos, M., Shinoda, K., Onodera, A., Kumagai, J., Yip, KH., Pant, H., Kokubo, K., Masahiro, K., Aoki, A., Obata-Ninomiya, K., Yokoyoda, K., Endo, Y., Kimura, MY., Nakayama, T.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 0091-6749(19) Issue: 2 Pages: 30340-9
- DOI
  10.1016/j.jaci.2019.02.024
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PROJECT-18K19466, KAKENHI-PUBLICLY-17H05787, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-20K20383, KAKENHI-PUBLICLY-18H04665, KAKENHI-PUBLICLY-19H04800, KAKENHI-PROJECT-19H05650
[Journal Article] DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells2018
- Author(s)
  Yamamoto, T., Endo, Y., Onodera, A., Hirahara, K., Asou, H., Nakajima, T., Kanno, T., Ouchi, Y., Uematsu, S., Nishimasu, H., Nureki, O., Tumes, D. J., Shimojo, N., and Nakayama, T.
- Journal Title
  
  Nature Communications
  
  Volume: 9 Issue: 1 Pages: 4231-4231
- DOI
  10.1038/s41467-018-06468-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-17H04257, KAKENHI-PROJECT-18H02571, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-17K19543, KAKENHI-PROJECT-20K20383, KAKENHI-PROJECT-17K07212, KAKENHI-PROJECT-17KK0189
[Journal Article] CXCR6+ST2+ memory T helper 2 cells induced the expression of major basic protein in eosinophils to reduce the fecundity of helminth2018
- Author(s)
  Obata-Ninomiya, K., Ishiwata, K., Nakano, H., Endo, Y., Ichikawa, T., Onodera, A., Hirahara, K., Okamoto, Y., Kanuka, H., Nakayama, T.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 42
- DOI
  10.1073/pnas.1714731115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PROJECT-18K07164, KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-20K20383
[Journal Article] Maintenance of memory-type pathogenic Th2 cells in the pathophysiology of chronic inflammation2018
- Author(s)
  Hirahara, K., Shinoda, K., Endo, Y., Ichikawa, T., and Nakayama, T
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 38 Issue: 1 Pages: 10-10
- DOI
  10.1186/s41232-018-0067-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H04665, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-20K20383
[Journal Article] Epigenetic regulation of T-helper cell differentiation, memory, and plasticity in allergic asthma2017
- Author(s)
  Tumes Damon J.、Papadopoulos Magdalene、Endo Yusuke、Onodera Atsushi、Hirahara Kiyoshi、Nakayama Toshinori
- Journal Title
  
  Immunol. Rev
  
  Volume: 278 Issue: 1 Pages: 8-19
- DOI
  10.1111/imr.12560
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08876, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-15K08522
[Journal Article] The obesity-related pathology and Th17 cells.2017
- Author(s)
  Endo, Y., Yokote, K., and Nakayama, T.
- Journal Title
  
  Cell. Mol. Life Sci.
  
  Volume: 74 Issue: 7 Pages: 1231-1245
- DOI
  10.1007/s00018-016-2399-3
- NAID
  40021094104
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01352, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-26293165
[Journal Article] Akt1-mediated Gata3 phosphorylation controls the repression of IFNγ in memory-type Th2 cells.2016
- Author(s)
  Hosokawa H, Tanaka T, Endo Y, Kato M, Shinoda K, Suzuki A, Motohashi S, Matsumoto M, Nakayama K, Nakayama T.
- Journal Title
  
  Nat Commun.
  
  Volume: - Issue: 1 Pages: 11289-11289
- DOI
  10.1038/ncomms11289
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14375, KAKENHI-PROJECT-25290078, KAKENHI-PUBLICLY-26116721, KAKENHI-PUBLICLY-15H01407, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-16H06224
[Journal Article] Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPARγ directs early activation of T cells.2016
- Author(s)
  Angela, M.,* Endo, Y.,* Asou, H. K., Yamamoto, T., Tumes, D. J., Tokuyama, H., Yokote, K., and Nakayama, T.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 13683-13683
- DOI
  10.1038/ncomms13683
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01352, KAKENHI-PLANNED-26115009, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-26293165
[Journal Article] Th2 cells in health and disease.2016
- Author(s)
  Nakayama T, Hirahara K, Onodera A, Endo Y, Hosokawa H, Shinoda K, Tumes DJ, Okamoto Y.
- Journal Title
  
  Annu Rev Immunol.
  
  Volume: 35 Issue: 1 Pages: 53-84
- DOI
  10.1146/annurev-immunol-051116-052350
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05483, KAKENHI-PROJECT-17K08876, KAKENHI-PUBLICLY-16H01352, KAKENHI-PROJECT-26221305, KAKENHI-PROJECT-16H06224, KAKENHI-PROJECT-15K08522
[Journal Article] Pathogenic memory type Th2 cells in allergic inflammation2014
- Author(s)
  Endo, Y., Hirahara, K., Yagi, R., Tumes, D. J., and Nakayama, T.
- Journal Title
  
  Trends Immunol
  
  Volume: 35(2) Issue: 2 Pages: 69-78
- DOI
  10.1016/j.it.2013.11.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25893032, KAKENHI-PROJECT-25893033
[Journal Article] 免疫記憶の制御2013
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  臨床免疫・アレルギ－科
  
  Volume: 60 Pages: 309-316
- NAID
  40019808031
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] The polycomb protein Ezh2 regulates differentiation and plasticity of CD4+ T helper type-1 and type-2 cells.2013
- Author(s)
  Tumes, D. J., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., Motohashi, S., and Nakayama, T.
- Journal Title
  
  Immunity
  
  Volume: 39 Issue: 5 Pages: 819-32
- DOI
  10.1016/j.immuni.2013.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249081, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-24790460, KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25860351, KAKENHI-PROJECT-25860352
[Journal Article] 免疫記憶の制御2013
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  臨床免疫・アレルギ−科
  
  Volume: 60(3) Pages: 309-316
- NAID
  40019808031
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] Functionally distinct Gata3/Chd4 complexes coordinately establish T helper 2 (Th2) cell identity.2013
- Author(s)
  Hosokawa H
- Journal Title
  
  Proc Natl Acad Sci U SA
  
  Volume: - Issue: 12 Pages: 4691-4696
- DOI
  10.1073/pnas.1220865110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300325, KAKENHI-PROJECT-22591093, KAKENHI-PROJECT-23659240, KAKENHI-PROJECT-23790523, KAKENHI-PUBLICLY-24116506, KAKENHI-PROJECT-24390239, KAKENHI-PROJECT-24790461, KAKENHI-PROJECT-25670438, KAKENHI-PROJECT-221S0002
[Journal Article] T細胞免疫記憶-メモリーT細胞の多様性と病因となる細胞集団-2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 5 Pages: 613-620
- NAID
  40019493231
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] PathogenicメモリーTh2細胞の同定とIL-5産生分子メカニズムの解明2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  医学のあゆみ
  
  Volume: 3 Pages: 266-267
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] IL-5産生pathogenicメモリーTh2相棒による慢性アレルギー炎症の制御2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  実験医学別刷
  
  Volume: 6 Pages: 899-904
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] Regulation of memory CD4 T-cell pool size and function by natural killer T cells in vivo. 109(42) : 16992-16997 (2012).2012
- Author(s)
  Iwamura, C., Shinoda, K., Endo, Y., Watanabe, Y., Tumes, J. D., Motohashi, S., Kawahara, K., Kinjo, Y., and Nakayama, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Issue: 42 Pages: 16992-16997
- DOI
  10.1073/pnas.1203494109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J56133, KAKENHI-PROJECT-22591093, KAKENHI-PROJECT-23592624, KAKENHI-PROJECT-23659240, KAKENHI-PROJECT-23890030, KAKENHI-PROJECT-24592083, KAKENHI-PROJECT-24790459, KAKENHI-PROJECT-24790461
[Journal Article] IL-5産生pathogenicメモリ−Th2細胞による慢性アレルギ−炎症の制御2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  実験医学別刷
  
  Volume: 30(6) Pages: 899-904
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] Pathogenicメモリ−Th2細胞の同定とIL-5産生分子メカニズムの解明2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  医学のあゆみ
  
  Volume: 242(3) Pages: 266-267
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] T細胞免疫記憶—メモリ−T細胞の多様性と病因となる細胞集団—2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  臨床免疫・アレルギ−科
  
  Volume: 58(5) Pages: 613-620
- NAID
  40019493231
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] 記憶CD4 T細胞によるウイルス感染防御、アレルギ−の臨床特集2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  ウイルス感染と免疫・アレルギ−
  
  Volume: 436(32) Pages: 23-27
- Data Source
  KAKENHI-PROJECT-24790461
[Journal Article] 記憶CD4 T細胞によるウィルス感染防御2012
- Author(s)
  遠藤裕介、中山俊憲
- Journal Title
  
  アレルギーの臨床
  
  Volume: 32 Pages: 23-27
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] 病原性Th17応答を規定する機能性脂質の同定と疾患制御2023
- Author(s)
  遠藤裕介
- Organizer
  第9回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04794
[Presentation] 病原性Th17応答を規定する機能性脂質の同定と疾患制御2023
- Author(s)
  遠藤裕介
- Organizer
  第9回がんと代謝研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] The novel function of lipid synthetic flux on Th17 cell differentiation and pathogenicity2023
- Author(s)
  Yusuke Endo
- Organizer
  52th JSI meeting
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04794
[Presentation] The novel function of lipid synthetic flux on Th17 cell differentiation and pathogenicity2023
- Author(s)
  Yusuke Endo
- Organizer
  52th JSI meeting
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] The novel function of lipid synthetic flux on Th17 cell differentiation and pathogenicity2023
- Author(s)
  Yusuke Endo
- Organizer
  RIKEN IMS-JSI Int Symposium on Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] The novel function of lipid synthetic flux on Th17 cell differentiation and pathogenicity2023
- Author(s)
  Yusuke Endo
- Organizer
  RIKEN IMS-JSI Int Symposium on Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-23H04794
[Presentation] Th17細胞、脂質代謝および肥満関連病態2022
- Author(s)
  遠藤裕介
- Organizer
  56th 糖尿病学の進歩
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 脂質代謝を基軸としたTh17 pathologyの解明と創薬モダリティの挑戦2022
- Author(s)
  遠藤裕介
- Organizer
  第95回日本生化学会大会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 脂質代謝を起点としたTh17 pathologyの解明と創薬モダリティの挑戦2022
- Author(s)
  遠藤裕介
- Organizer
  日本生化学会関東支部例会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 肥満関連疾患においてPathogenic T細胞応答を規定する脂質代謝コード2022
- Author(s)
  遠藤裕介
- Organizer
  第３回心・腎・代謝から生活習慣病を考える会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] Lipid metabolism in Th17 cell function2022
- Author(s)
  Yusuke Endo
- Organizer
  17th BioActive Lipids in cancer, inflammation and related diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] Fatty acid metabolism in the generation of memory precursor population of CD4+ T cells2022
- Author(s)
  Yusuke Endo
- Organizer
  51th JSI meeting Afternoon seminar
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] Fatty acid metabolism directs cell fate decision During the generation of memory CD4+ T cells2021
- Author(s)
  Yusuke Endo
- Organizer
  FIMSA2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点解明2021
- Author(s)
  遠藤裕介
- Organizer
  第7回JFAS
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] 代謝で免疫を制御する：T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点2021
- Author(s)
  遠藤裕介
- Organizer
  動脈硬化Update
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] Fatty acid metabolism directs cell fate decision During the generation of memory CD4+ T cells2021
- Author(s)
  Yusuke Endo
- Organizer
  FIMSA2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] Fatty acid metabolism directs cell fate decision During the generation of memory CD4+ T cells2021
- Author(s)
  Yusuke Endo
- Organizer
  JSI meeting 2021
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] Fatty acid metabolism directs cell fate decision During the generation of memory CD4+ T cells2021
- Author(s)
  Yusuke Endo
- Organizer
  JSI meeting 2021
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] 細胞内脂質の低下を感知して抗ウイルス応答を発揮するT細胞特有のmetabolic regulomeの同定2021
- Author(s)
  遠藤裕介
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] 代謝で免疫を制御する：疾患を引き起こす脂質イムノメタボリズムの分子作用点2021
- Author(s)
  遠藤裕介
- Organizer
  静岡　皮膚診療Update
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点解明2021
- Author(s)
  遠藤裕介
- Organizer
  第7回JFAS
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] 代謝で免疫を制御する：T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点2021
- Author(s)
  遠藤裕介
- Organizer
  動脈硬化Update
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] Ｔ細胞の機能分化を司る脂質イムノメタボリズムの分子作用点解明2021
- Author(s)
  遠藤裕介
- Organizer
  第7回JFAS
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 代謝で免疫を制御する：疾患を引き起こす脂質イムノメタボリズムの分子作用点2021
- Author(s)
  遠藤裕介
- Organizer
  静岡　皮膚診療Update
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点解明2021
- Author(s)
  遠藤裕介
- Organizer
  第7回JFAS
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 細胞内脂質の低下を感知して抗ウイルス応答を発揮するT細胞特有のmetabolic regulomeの同定2021
- Author(s)
  遠藤裕介
- Organizer
  第94回日本生化学大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点解明2020
- Author(s)
  遠藤裕介
- Organizer
  第181回東京脂質談話会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を起点とする「代謝-免疫-疾患」の分子メカニズム解明2020
- Author(s)
  遠藤裕介
- Organizer
  第872回千葉県がんセンター集談会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点2020
- Author(s)
  遠藤裕介
- Organizer
  第43回日本分子生物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 脂肪酸を起点とする「代謝-免疫-疾患」の分子メカニズム解明2020
- Author(s)
  遠藤裕介
- Organizer
  第872回千葉県がんセンター集談会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] T細胞の機能分化を司る脂質イムノメタボリズムの分子作用点2020
- Author(s)
  遠藤裕介
- Organizer
  第43回日本分子生物学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] 免疫システムと病気～代謝からアレルギーの克服を目指す～2020
- Author(s)
  遠藤裕介
- Organizer
  大人が楽しむ科学教室2020
- Invited
- Data Source
  KAKENHI-PROJECT-20K21618
[Presentation] 免疫システムと病気～代謝からアレルギーの克服を目指す～2020
- Author(s)
  遠藤裕介
- Organizer
  大人が楽しむ科学教室2020
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 脂肪酸代謝システムによる免疫記憶システムのコントロール2020
- Author(s)
  遠藤裕介
- Organizer
  アジレント・テクノロジー細胞解析セミナー2020
- Invited
- Data Source
  KAKENHI-PROJECT-20H03455
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2019
- Author(s)
  遠藤　裕介
- Organizer
  愛媛大学プロテオサイエンスシンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2019
- Author(s)
  遠藤　裕介
- Organizer
  愛媛大学プロテオサイエンスシンポジウム
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] 脂肪酸代謝を基軸とする「肥満-免疫-疾患」スパイラルの分子機構解2019
- Author(s)
  遠藤裕介
- Organizer
  第40回日本肥満学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 不均一な脂肪酸代謝動態からとらえる記憶T前駆細胞の同定2019
- Author(s)
  遠藤裕介
- Organizer
  第42回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 病原性記憶Th2細胞と慢性アレルギー疾患2019
- Author(s)
  遠藤裕介
- Organizer
  日本アレルギー学会専門医認定教育セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2019
- Author(s)
  遠藤裕介
- Organizer
  愛媛大学プロテオサイエンスシンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2019
- Author(s)
  遠藤裕介
- Organizer
  第19回日本加齢医学学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] ACC1 determines memory potential of individual CD4+ T cells by regulating de novo fatty acid biosynthesis2019
- Author(s)
  Endo Y.
- Organizer
  60th ICBL
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2019
- Author(s)
  遠藤裕介
- Organizer
  第92回日本生化学会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] Fatty acid metabolism directs cell fate decision during the generation of memory CD4 T cells2019
- Author(s)
  Endo Y.
- Organizer
  1st CU-UT workshop
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2018
- Author(s)
  遠藤　裕介
- Organizer
  東海大学医学会セミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] Elucidation of the role of fatty acid metabolism in Th17 cell differentiation under obese conditions2018
- Author(s)
  Yusuke Endo
- Organizer
  he 2nd Chiba University-UC San Diego Symposium “Mucosal Immunology, Allergy and Vaccine”
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04665
[Presentation] 脂肪酸を基軸とする「代謝-免疫-疾患」スパイラルの分子機構解明2018
- Author(s)
  遠藤　裕介
- Organizer
  東海大学医学会セミナー
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Elucidation of the role of fatty acid metabolism in Th17 cell differentiation under obese conditions2018
- Author(s)
  Yusuke Endo
- Organizer
  The 2nd Chiba University-UC San Diego Symposium “Mucosal Immunology, Allergy and Vaccine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Elucidation of the role of fatty acid metabolism in Th17 cell differentiation under obese conditions.2017
- Author(s)
  Endo, Y., and Nakayama, T.
- Organizer
  7th International Workshop of Kyoto T Cell Conference,
- Place of Presentation
  京都大学医学部・芝蘭会館（京都府京都市）
- Year and Date
  2017-03-17
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Presentation] Elucidation of the role of fatty acid metabolism in Th17 cell differentiation under obese conditions.2017
- Author(s)
  Endo, Y., and Nakayama, T.
- Organizer
  7th International Workshop of Kyoto T Cell Conference,
- Place of Presentation
  京都大学医学部・芝蘭会館（京都府京都市）
- Year and Date
  2017-03-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Elucidation of the role of fatty acid metabolism in Th cell differentiation under obese conditions.2017
- Author(s)
  Endo, Y.
- Organizer
  AAI Annual Meeting Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Presentation] Elucidation of the role of fatty acid metabolism in Th cell differentiation under obese conditions.2017
- Author(s)
  Endo, Y.
- Organizer
  AAI Annual Meeting Immunology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Th2 (Tpath2) cells in airway inflammation.2017
- Author(s)
  Nakayama, T., Endo, Y., Shinoda, K., and Hirahara, K.
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  京都大学医学部・芝蘭会館（京都府京都市）
- Year and Date
  2017-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Presentation] Elucidation of the role of fatty acid metabolism in Th cell differentiation under obese conditions.2017
- Author(s)
  Endo, Y.
- Organizer
  Leibniz-AMED Workshop on Chronic Inflammation, Infection and Healthy Aging
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Presentation] Memory type pathogenic Th2 (Tpath2) cells in airway inflammation.2017
- Author(s)
  Nakayama, T., Endo, Y., Shinoda, K., and Hirahara, K.
- Organizer
  7th International Workshop of Kyoto T Cell Conference
- Place of Presentation
  京都大学医学部・芝蘭会館（京都府京都市）
- Year and Date
  2017-03-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Elucidation of the role of fatty acid metabolism in Th cell differentiation under obese conditions.2017
- Author(s)
  Endo, Y.
- Organizer
  Leibniz-AMED Workshop on Chronic Inflammation, Infection and Healthy Aging
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Obesity drives Th17 cell differentiation by inducing the carboxylase ACC1 and fatty acid biosynthesis.2016
- Author(s)
  Endo, Y., and Nakayama, T.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Fatty acid metabolic reprogramming via mTOR-mediated induction of PPARγ directs early activation of T cells.2016
- Author(s)
  Endo, Y., Yamamoto, T., Tumes, D. J., and Nakayama, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県宜野湾市)
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16H06224
[Presentation] Fatty acid metabolic reprogramming via mTOR-mediated induction of PPARγ directs early activation of T cells.2016
- Author(s)
  Endo, Y., Yamamoto, T., Tumes, D. J., and Nakayama, T.
- Organizer
  第45回日本免疫学会総会・学術集会
- Place of Presentation
  沖縄コンベンションセンター(沖縄県宜野湾市)
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Presentation] Obesity drives Th17 cell differentiation by inducing the carboxylase ACC1 and fatty acid biosynthesis.2016
- Author(s)
  Endo, Y., and Nakayama, T.
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PUBLICLY-16H01352
[Presentation] Functionally distinct Gata3/Chd4 complexes coordinately establish Th2 cell identity2013
- Author(s)
  Hosokawa, H., Tamaki, Y., Endo, Y., Tumes, D. J., Angela. M., Sarkar, M. H., and Nakayama, T.
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  幕張
- Year and Date
  2013-12-11
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Generation and maintenance of pathogenic memory CD4 T cells2013
- Author(s)
  Nakayama, T., Endo, Y., Onodera, A., and Tumes, D. J.
- Organizer
  The 3rd CSI/JSI/KAI Joint Symposium on Immunology
- Place of Presentation
  Korea
- Year and Date
  2013-12-02
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Pathogenic memory Th2 cells in the airway and regulation by activated NKT cells in vivo2013
- Author(s)
  Nakayama, T., Iwamura, C., Shinoda, K., and Endo, Y.
- Organizer
  第63回日本アレルギ−学会秋季学術大会
- Place of Presentation
  東京
- Year and Date
  2013-11-30
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] The histone methyltransferase Ezh2 regulates differentiation and plasticity of CD4 T helper cells2013
- Author(s)
  Tumes, D., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., and Nakayama, T.
- Organizer
  AAI Annual Meeting
- Place of Presentation
  Honolulu, USA
- Year and Date
  2013-05-06
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Regulation of memory CD4 T cell pool size and function by NKT cells in vivo2012
- Author(s)
  Iwamura, C., Endo, Y., Onodera, A., Watanabe, Y., Suzuki, A., Kinjo, Y., and Nakayama, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2012-12-06
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Generation and maintenance of memory CD4 T cells2012
- Author(s)
  Nakayama, T., Endo, Y., Kuwahara, M., Yamashita, M., Iwamura, C., Shinoda, K., and Tokoyoda, K.
- Organizer
  THE 34th NAITO CONFERENCE ON Infection, Immunity, and their control for Health
- Place of Presentation
  Sapporo
- Year and Date
  2012-10-18
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Regulation of memory CD4 T cell pool size and function by NKT cells in vivo.
- Author(s)
  Iwamura, C., Endo, Y., Onodera, A., Watanabe, Y., Suzuki, A., Kinjo, Y., and Nakayama, T.
- Organizer
  第41回日本免疫学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] The histone methyltransferase Ezh2 regulates differentiation and plasticity of CD4 T helper cells.
- Author(s)
  Tumes, D., Onodera, A., Suzuki, A., Shinoda, K., Endo, Y., Iwamura, C., Hosokawa, H., Koseki, H., Tokoyoda, K., Suzuki, Y., and Nakayama, T.
- Organizer
  AAI Annual Meeting
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Generation and maintenance of memory CD4 T cells.
- Author(s)
  Nakayama, T., Endo, Y., Kuwahara, M., Yamashita, M., Iwamura, C., Shinoda, K., and Tokoyoda, K.
- Organizer
  THE 34th NAITO CONFERENCE ON infection, Immunity, and their control for Health.
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Functionally distinct Gata3/Chd4 complexes coordinately establish Th2 cell identity.
- Author(s)
  Hosokawa, H., Tamaki, Y., Endo, Y., Tumes, D. J., Angela. M., Sarkar, M. H., and Nakayama, T.
- Organizer
  第42回日本免疫学会総会学術集会
- Place of Presentation
  幕張
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Pathogenic memory Th2 cells in the airway and regulation by activated NKT cells in vivo.
- Author(s)
  Nakayama, T., Iwamura, C., Shinoda, K., and Endo, Y.
- Organizer
  第63回日本アレルギ－学会秋季学術大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790461
[Presentation] Generation and maintenance of pathogenic memory CD4 T cells.
- Author(s)
  Nakayama, T., Endo, Y., Onodera, A., and Tumes, D. J.
- Organizer
  The 3rd CSI/JSI/KAI Joint Symposium on Immunology
- Place of Presentation
  Korea
- Data Source
  KAKENHI-PROJECT-24790461

1. HOSOKAWA HIROYUKI (60431756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 宮前多佳子 (90322354)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 井上祐三朗 (00456063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川上英良 (30725338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 藤尾圭志 (70401114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. NAKAYAMA TOSHINORI

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. MOTOHASHI Shinichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. NAKAYAMA Yukiteru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 菅野敏生

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 平原潔

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
11. 田中知明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 平野健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 関直彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 中嶋隆裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 藤生克仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 岡本美孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 岡本好海

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 小野寺淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 大石由美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Endo Yusuke 遠藤 裕介

ENDO Yusuke 遠藤 裕介

Research Projects

Research Products

Co-Researchers

Th17細胞の自己認識における脂質代謝の作用と病原性応答への意義解明Principal Investigator

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リンパ球系譜のRORgt多機能性を司る脂質代謝経路の解明Principal Investigator

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Identification of pathogenic T progenitors using lipid droplet fate-mapping micePrincipal Investigator

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T細胞が認識する肥満特有の自己指向性免疫の解明Principal Investigator

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Elucidation of immunogenetic features of childhood-onset SLE by referencing adult peripheral blood single-cell data using AI

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Development of Novel Therapy for Allergic Diseases Using the CRISPR/Cas9 TGA SystemPrincipal Investigator

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Identification of functional lipids that control Th17/Treg balance in an obese environmentPrincipal Investigator

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Stage-specific roles of Notch signaling on induction of T cell development from hematopoietic progenitor cells

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リポクオリティが制御する脂質リガンドに依存したRORγt機能多様性の解明Principal Investigator

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炎症性Th17細胞においてRORγtが認識するリポクオリティ分子機構の解明Principal Investigator

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Elucidation of the mechanism of asthma condition deterioration in the obese environment and the establish of treatment developmentPrincipal Investigator

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The regulation of memory Th2 cell-dependent allergic airway inflammation through the IL-33-T1/ST2 pathway.Principal Investigator

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[Book] Chronic Inflammation Mechanisms and Regulation2016

Author(s)

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Endo Yusuke 遠藤裕介

ENDO Yusuke 遠藤裕介