Sun Lue 孫略

Researcher Number	40757704
Other IDs
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2019 – 2024: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究員 2017 – 2018: 筑波大学, 医学医療系, 助教 2016: 産業医科大学, 産業生態科学研究所, 訪問研究員 2015: 産業医科大学, 産業生態科学研究所, 産業医学基礎研究医員
Review Section/Research Field	Principal Investigator Neurosurgery / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 63020:Radiation influence-related / Basic Section 52040:Radiological sciences-related Except Principal Investigator Medium-sized Section 58:Society medicine, nursing, and related fields / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 放射線 / 放射線治療 / がん / 生体材料 / 免疫治療 / 無機材料 / ミトコンドリア / がん幹細胞 / 脳腫瘍 / 光医療 … More / 急性障害 / 緊急被ばく医療 / 光治療 / 免疫 / 抗腫瘍免疫 / レドックス / 代謝 / 浸潤 / 転移 / 脳腫瘍幹細胞 / エネルギー代謝 / ESR / レドックスバランス / 放射線抵抗性 / ミトコンドリア呼吸 / 解糖系 / 酸化ストレス … More Except Principal Investigator グルタチオン / 放射線白内障 / 血液抗酸化能 / 低線量率被ばく / 低線量被ばく / 慢性被ばく / 晩期障害 / プロテオーム / 質量分析イメージング / Id-1 / イメージング / 腫瘍 / がん治療 / 放射線 / 細胞老化 Less

放射線増感と抗腫瘍免疫活性化を実現する低分子－無機材料コンビネーション薬剤の開発Principal Investigator
- Principal Investigator
  
  孫略
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
低強度光照射による急性放射線障害軽減に関する研究Principal Investigator
- Principal Investigator
  
  孫略
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Antioxidant capacity as an indicator of radiation late effects
- Principal Investigator
  
  MORITAKE Takashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  National Institutes for Quantum Science and Technology
Analysis of the Mechanism of Tumor Immunomodulation through the Combination of Radiotherapy and Mesoporous Silica ParticlesPrincipal Investigator
- Principal Investigator
  
  Sun Lue
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of a MS imaging-based diagnosis for novel cancer senotherapy
- Principal Investigator
  
  Yasui Hironobu
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Hokkaido University
Investigation of mechanism for radiation induced brain tumor stem cell migrationPrincipal Investigator
- Principal Investigator
  
  Sun Lue
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  University of Tsukuba
Energy and ROS metabolism in radioresistant brain tumor stem cellsPrincipal Investigator
- Principal Investigator
  
  Sun Lue
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurosurgery
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2022 2021 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Analysis of whole-blood antioxidant capacity after chronic and localized irradiation using the i-STrap method2021
- Author(s)
  Sun Lue、Inaba Yohei、Sogo Yu、Morikawa Kumi、Kunugita Naoki、Chida Koichi、Moritake Takashi
- Journal Title
  
  Journal of Radiation Research
  
  Volume: 63 Issue: 1 Pages: 30-35
- DOI
  10.1093/jrr/rrab099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12329, KAKENHI-PROJECT-18H03376, KAKENHI-PROJECT-21K19683
[Journal Article] Abscopal Effect Induced by a Combined Treatment with Anti-PD-1 Antibody and BM-DCs after X-ray in a Melanoma Mouse Model2018
- Author(s)
  Yuzi Wang, Lue Sun, Xiaokang Li, Koji Tsuboi
- Journal Title
  
  CANCER SCIENCE
  
  Volume: 109 Pages: 117-117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16668
[Journal Article] Energy and ROS metabolism in radioresistant brain tumor cells2018
- Author(s)
  Sun Lue、Yuzi Wang、Masaoki Kohzaki、Tsuboi Koji
- Journal Title
  
  CANCER SCIENCE
  
  Volume: 109 Pages: 267-267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16668
[Journal Article] A combined local treatment with anti-PD-1 antibody and bone marrow derived dendritic cells after x-ray irradiation to subcutaneous melanoma in a murine model.2017
- Author(s)
  Yuzi Wang, Lue Sun, Xiaokang Li, Koji Tsuboi
- Journal Title
  
  Journal of Clinical Oncology
  
  Volume: 35 Issue: 15_suppl Pages: e14541-e14541
- DOI
  10.1200/jco.2017.35.15_suppl.e14541
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16668
[Journal Article] Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets2017
- Author(s)
  Lue Sun, Takashi Moritake, Kazuya Ito, Yoshitaka Matsumoto, Hironobu Yasui, Hidehiko Nakagawa, Aki Hirayama, Osamu Inanami, and Koji Tsuboi
- Journal Title
  
  PlosOns
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06804
[Journal Article] Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets2017
- Author(s)
  Sun Lue、Moritake Takashi、Ito Kazuya、Matsumoto Yoshitaka、Yasui Hironobu、Nakagawa Hidehiko、Hirayama Aki、Inanami Osamu、Tsuboi Koji
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 4 Pages: 1-24
- DOI
  10.1371/journal.pone.0176162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16668, KAKENHI-PLANNED-26111012, KAKENHI-PROJECT-16H05103, KAKENHI-PROJECT-16H05387, KAKENHI-PROJECT-15K09983, KAKENHI-PROJECT-15K09986, KAKENHI-PROJECT-16K15573
[Journal Article] 包括的代謝解析による放射線抵抗性がん幹細胞の特性解析2015
- Author(s)
  孫略、盛武敬、香﨑正宙、岡﨑龍史
- Journal Title
  
  日本放射線影響学会第1回放射線ワークショップ講演論文集
  
  Volume: 0 Pages: 66-67
- Data Source
  KAKENHI-PROJECT-15H06804
[Presentation] 複合ナノ材料による放射線免疫治療の最適化2022
- Author(s)
  孫略、杉浦悠紀、十河友、伊藤敦夫
- Organizer
  第20回産総研・産技連LS-BT合同研究発表会
- Data Source
  KAKENHI-PROJECT-20K16811
[Presentation] 放射線治療と低分子薬を組み合わせた免疫原性細胞死の高効率誘導2022
- Author(s)
  孫略、森川久未、杉浦悠紀、十河友、伊藤敦夫
- Organizer
  第26回日本がん免疫学会総会
- Data Source
  KAKENHI-PROJECT-20K16811
[Presentation] 放射線被ばくによる生体の抗酸化能の変化とその意義に関する研究2021
- Author(s)
  孫略
- Organizer
  日本放射線影響学会第64回大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19683
[Presentation] A Combined Local Treatment with Anti-PD-1 Antibody and Bone Marrow Derived Dendritic Cells after X-ray Irradiation to Subcutaneous Melanoma in a Murine Model.2017
- Author(s)
  Yuzi Wang, Lue Sun, Xiaokang Li and Koji Tsuboi.
- Organizer
  The 2017 ASCO Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16668
[Presentation] Abscopal Effect Induced by a Combined Treatment with Anti-PD-1 Antibody and BM-DCs after X-ray in a Melanoma Mouse Model2017
- Author(s)
  Yuzi Wang, Lue Sun, Xiaokang Li, Koji Tsuboi
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K16668
[Presentation] Energy and ROS metabolism in radioresistant brain tumor cells.2017
- Author(s)
  Lue Sun, Takashi Moritake, Yoshitaka Matsumoto, Yuzi Wang, Masaoki Kohzaki, Akira Ootsuyama, Ryuji Okazaki and Koji Tsuboi.
- Organizer
  第76回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16668
[Presentation] Energy and ROS metabolism in radioresistant brain tumor stem cells.2016
- Author(s)
  Lue Sun
- Organizer
  Loma Linda University Medical Center
- Place of Presentation
  Loma Linda (アメリカ)
- Invited
- Data Source
  KAKENHI-PROJECT-15H06804
[Presentation] Energy and ROS Metabolism in Radioresistant Brain Tumor Cells2016
- Author(s)
  Lue Sun, Takashi Moritake, Masaoki Kohzaki, Akira Ootsuyama and Ryuji Okazaki
- Organizer
  The Society for Redox Biology and Medicine’s 23rd Annual Meeting
- Place of Presentation
  サンフランシスコ (アメリカ)
- Year and Date
  2016-11-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06804
[Presentation] 髄芽腫幹細胞のエネルギー代謝機構と放射線抵抗性2015
- Author(s)
  孫略、盛武敬、香﨑正宙、岡﨑龍史
- Organizer
  第52回放射線影響懇話会
- Place of Presentation
  かごしま県民交流センター(鹿児島市、鹿児島県)
- Year and Date
  2015-08-29
- Data Source
  KAKENHI-PROJECT-15H06804
[Presentation] 包括的代謝解析による放射線抵抗性がん幹細胞の特性解析2015
- Author(s)
  孫略、盛武敬、香﨑正宙、岡﨑龍史
- Organizer
  日本放射線影響学会第1回放射線ワークショップ
- Place of Presentation
  富山大学五福キャンパス(富山市、富山県)
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15H06804

1. Yasui Hironobu (10570228)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. MORITAKE Takashi (50450432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 稲波修 (10193559)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 東川桂 (10756878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 久下裕司 (70321958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鈴木正敏 (60515823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 古場裕介 (10583073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 杉浦悠紀 (70755040)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 福田隆史 (50357894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 堀口諭吉 (50609758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中村麻子 (70609601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. YAMADA Shokei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Sun Lue 孫 略

Research Projects

Research Products

Co-Researchers

放射線増感と抗腫瘍免疫活性化を実現する低分子－無機材料コンビネーション薬剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

低強度光照射による急性放射線障害軽減に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Antioxidant capacity as an indicator of radiation late effects

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the Mechanism of Tumor Immunomodulation through the Combination of Radiotherapy and Mesoporous Silica ParticlesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a MS imaging-based diagnosis for novel cancer senotherapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of mechanism for radiation induced brain tumor stem cell migrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Energy and ROS metabolism in radioresistant brain tumor stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Analysis of whole-blood antioxidant capacity after chronic and localized irradiation using the i-STrap method2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Abscopal Effect Induced by a Combined Treatment with Anti-PD-1 Antibody and BM-DCs after X-ray in a Melanoma Mouse Model2018

Author(s)

Journal Title

Data Source

[Journal Article] Energy and ROS metabolism in radioresistant brain tumor cells2018

Author(s)

Journal Title

Data Source

[Journal Article] A combined local treatment with anti-PD-1 antibody and bone marrow derived dendritic cells after x-ray irradiation to subcutaneous melanoma in a murine model.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets2017

Author(s)

Journal Title

Data Source

[Journal Article] Metabolic analysis of radioresistant medulloblastoma stem-like clones and potential therapeutic targets2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 包括的代謝解析による放射線抵抗性がん幹細胞の特性解析2015

Author(s)

Journal Title

Data Source

[Presentation] 複合ナノ材料による放射線免疫治療の最適化2022

Author(s)

Organizer

Sun Lue 孫略