KUGA DAISUKE 空閑太亮

… Alternative Names

Kuga Daisuke 空閑太亮

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Researcher Number	40759932
Affiliation (Current)	2025: 九州大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 九州大学, 大学病院, 助教 2018: 慶應義塾大学, 医学部(信濃町), 助教 2017: 慶應義塾大学, 大学病院, 助教 2016 – 2017: 九州大学, 医学研究院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery / Radiation science
Keywords	Principal Investigator バイオマーカー / 下垂体腺腫 / 脳腫瘍 / 頭蓋内胚細胞腫瘍 / 胚細胞腫瘍 / bevacizumab / Glioblastom / 膠芽腫 / liquid biopsy / glioblastoma … More Except Principal Investigator … More glioma / IDH / molecular diagnosis / リキッドバイオプシー / CSF / digital PCR / WHO2021 / MLPA / liquid biopsy / グリオーマ / 神経膠腫 / 膠芽腫 / 脳腫瘍 / TERT / H3F3A / glioblastoma / 免疫ゲノム / ミクログリア / 免疫免疫環境 / エクソソーム / 直接誘導ミクログリア様細胞 / 免疫微小環境 / 分子診断 / cfDNA / H3 / mesenchymal / Glioblastoma / mitochondria / HDAC7 / 放射線科学 / 内科系臨床医学 / 医歯薬学 / 分子イメージング / 神経放射線 / APTイメージング / CEST / MRI / ラジオゲノミクス / ゲノム / 脳・神経 / トランスレーショナルリサーチ / 癌 / 遺伝子 / point mutation / H3 G34R / H3 K27M / BRAF / HRM / diffuse glioma / WHO2016 / genetic analysis / 頚動脈プラーク / 頚動脈プラーク破綻 / micro RNA / 頸動脈プラーク / マイクロRNA / エピジェネティクス / プラーク破綻 Less

Comprehensive molecular diagnosis of glioma by liquid biopsy
- Principal Investigator
  
  秦暢宏
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Oita University
Elucidation of glioma immune microenvironment heterogeneity based on immunogenomics by liquid biopsy
- Principal Investigator
  
  Mizoguchi Masahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyushu University
Epigenetic Analysis of Blood cfDNA in Pituitary Adenomas and Clinical ApplicationsPrincipal Investigator
- Principal Investigator
  
  Daisuke Kuga
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyushu University
Development of non-invasive diagnostic system of glioma by liquid biopsy liquid biopsy
- Principal Investigator
  
  Hata Nobuhiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Oita University
  Kyushu University
Development of an innovative diagnostic / therapeutic system for intracranial germ cell tumorsPrincipal Investigator
- Principal Investigator
  
  KUGA DAISUKE
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kyushu University
ラジオゲノミクス、定量的画像解析に基づく多角的な脳腫瘍診断法の開発
- Principal Investigator
  
  山下孝二
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
Monitoring high grade glioma and evaluation of prognostic value by APT imaging
- Principal Investigator
  
  TOGAO OSAMU
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Kyushu University
Functional significance of HDAC7 expression in glioblastoma
- Principal Investigator
  
  Yoshimoto Koji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kagoshima University
  Kyushu University
Elucidation of epigenetic change in carotid artery plaque rupture
- Principal Investigator
  
  Sayama Tetsuro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyushu University
Development of comprehensive platform for molecular diagnosis of glioma
- Principal Investigator
  
  Hata Nobuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyushu University
  National Hospital Organization, Kyushu Medical Center (Clinical Institute)
Detection of blood biomarker in the patients' with Bevacizumab treated glioblastomasPrincipal Investigator
- Principal Investigator
  
  Kuga Daisuke
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] In‐house molecular diagnosis of diffuse glioma updating the revised <scp>WHO</scp> classification by a platform of the advanced medical care system, <scp>Senshin‐Iryo</scp>2024
- Author(s)
  Hata Nobuhiro、Fujioka Yutaka、Otsuji Ryosuke、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Amemiya Takeo、Noguchi Naoki、Sako Aki、Fujiki Minoru、Mizoguchi Masahiro、Yoshimoto Koji
- Journal Title
  
  Neuropathology
  
  Volume: - Issue: 5 Pages: 344-350
- DOI
  10.1111/neup.12970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03044
[Journal Article] Liquid Biopsy for Glioma Using Cell-Free DNA in Cerebrospinal Fluid2024
- Author(s)
  Otsuji Ryosuke、Fujioka Yutaka、Hata Nobuhiro、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Nakamizo Akira、Mizoguchi Masahiro、Yoshimoto Koji
- Journal Title
  
  Cancers
  
  Volume: 16 Issue: 5 Pages: 1009-1009
- DOI
  10.3390/cancers16051009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16690, KAKENHI-PROJECT-23K08545, KAKENHI-PROJECT-21H03044
[Journal Article] Supramaximal Resection Can Prolong the Survival of Patients with Cortical Glioblastoma: A Volumetric Study2023
- Author(s)
  OTSUJI Ryosuke、HATA Nobuhiro、FUNAKOSHI Yusuke、KUGA Daisuke、TOGAO Osamu、HATAE Ryusuke、SANGATSUDA Yuhei、FUJIOKA Yutaka、TAKIGAWA Kosuke、SAKO Aki、KIKUCHI Kazufumi、YOSHITAKE Tadamasa、YAMAMOTO Hidetaka、MIZOGUCHI Masahiro、YOSHIMOTO Koji
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 63 Issue: 8 Pages: 364-374
- DOI
  10.2176/jns-nmc.2022-0351
- ISSN
  0470-8105, 1349-8029
- Year and Date
  2023-08-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08545, KAKENHI-PROJECT-23K10453, KAKENHI-PROJECT-21H03044
[Journal Article] Changes in the Relapse Pattern and Prognosis of Glioblastoma After Approval of First-Line Bevacizumab: A Single-Center Retrospective Study2022
- Author(s)
  Funakoshi Y, Takigawa K, Hata N, Kuga D, Hatae R, Sangatsuda Y, Fujioka Y, Otsuji R, Sako A, Yoshitake T, Togao O, Hiwatashi A, Iwaki T, Mizoguchi M, Yoshimoto K.
- Journal Title
  
  World Neurosurg
  
  Volume: 159 Pages: e479-e487
- DOI
  10.1016/j.wneu.2021.12.075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H03044
[Journal Article] Liquid biopsy with multiplex ligation-dependent probe amplification targeting cell-free tumor DNA in cerebrospinal fluid from patients with adult diffuse glioma2022
- Author(s)
  Ryosuke Otsuji
- Journal Title
  
  Neuro oncology advance
  
  Volume: 5 Issue: 1 Pages: 1-11
- DOI
  10.1093/noajnl/vdac178
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16690, KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392
[Journal Article] A case of ganglioglioma grade 3 with H3 K27M mutation arising in the medial temporal lobe in an elderly patient2022
- Author(s)
  Fujii Yutaro、Hatae Ryusuke、Hata Nobuhiro、Suzuki Satoshi O.、Sangatsuda Yuhei、Takigawa Kosuke、Funakoshi Yusuke、Fujioka Yutaka、Kuga Daisuke、Mizoguchi Masahiro、Iwaki Toru、Yoshimoto Koji
- Journal Title
  
  Neuropathology
  
  Volume: 42 Issue: 3 Pages: 197-203
- DOI
  10.1111/neup.12793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Clinical implications of molecular analysis in diffuse glioma stratification2021
- Author(s)
  Mizoguchi Masahiro、Hata Nobuhiro、Kuga Daisuke、Hatae Ryusuke、Akagi Yojiro、Sangatsuda Yuhei、Fujioka Yutaka、Takigawa Kosuke、Funakoshi Yusuke、Suzuki Satoshi O.、Iwaki Toru
- Journal Title
  
  Brain Tumor Pathology
  
  Volume: 38 Issue: 3 Pages: 210-217
- DOI
  10.1007/s10014-021-00409-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392
[Journal Article] Current trend in treatment of glioblastoma in Japan: a national survey using the diagnostic procedure combination database (J-ASPECT study-glioblastoma)2021
- Author(s)
  Funakoshi Yusuke、Hata Nobuhiro、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Takigawa Kosuke、Yoshimoto Koji、Mizoguchi Masahiro、Iihara Koji
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Issue: 8 Pages: 1441-1449
- DOI
  10.1007/s10147-021-01929-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Volumetric study reveals the relationship between outcome and early radiographic response during bevacizumab-containing chemoradiotherapy for unresectable glioblastoma2021
- Author(s)
  Takigawa Kosuke、Hata Nobuhiro、Michiwaki Yuhei、Hiwatashi Akio、Yonezawa Hajime、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Funakoshi Yusuke、Otsuji Ryosuke、Sako Aki、Togao Osamu、Yoshiura Takashi、Yoshimoto Koji、Mizoguchi Masahiro
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 154 Issue: 2 Pages: 187-196
- DOI
  10.1007/s11060-021-03812-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03044, KAKENHI-PROJECT-20K09392
[Journal Article] Molecular diagnosis of diffuse glioma using a chip-based digital PCR system to analyze IDH, TERT, and H3 mutations in the cerebrospinal fluid2021
- Author(s)
  Fujioka Yutaka、Hata Nobuhiro、Akagi Yojiro、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Michiwaki Yuhei、Amemiya Takeo、Takigawa Kosuke、Funakoshi Yusuke、Sako Aki、Iwaki Toru、Iihara Koji、Mizoguchi Masahiro
- Journal Title
  
  Journal of Neuro-Oncology
  
  Volume: 152 Issue: 1 Pages: 47-54
- DOI
  10.1007/s11060-020-03682-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Clinical significance of CDKN2A homozygous deletion in combination with methylated <i>MGMT</i> status for <i>IDH</i> ‐wildtype glioblastoma2021
- Author(s)
  Funakoshi Yusuke、Hata Nobuhiro、Takigawa Kosuke、Arita Hideyuki、Kuga Daisuke、Hatae Ryusuke、Sangatsuda Yuhei、Fujioka Yutaka、Sako Aki、Umehara Toru、Yoshitake Tadamasa、Togao Osamu、Hiwatashi Akio、Yoshimoto Koji、Iwaki Toru、Mizoguchi Masahiro
- Journal Title
  
  Cancer Medicine
  
  Volume: 10 Issue: 10 Pages: 3177-3187
- DOI
  10.1002/cam4.3860
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09392
[Journal Article] Relevance of calcification and contrast enhancement pattern for molecular diagnosis and survival prediction of gliomas based on the 2016 World Health Organization Classification2019
- Author(s)
  Michiwaki Yuhei、Hata Nobuhiro、Mizoguchi Masahiro、Hiwatashi Akio、Kuga Daisuke、Hatae Ryusuke、Akagi Yojiro、Amemiya Takeo、Fujioka Yutaka、Togao Osamu、Suzuki Satoshi O.、Yoshimoto Koji、Iwaki Toru、Iihara Koji
- Journal Title
  
  Clinical Neurology and Neurosurgery
  
  Volume: 187 Pages: 105556-105556
- DOI
  10.1016/j.clineuro.2019.105556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08970
[Journal Article] Pediatric ganglioglioma with an H3 K27M mutation arising from the cervical spinal cord2018
- Author(s)
  Okuda Tomohiro、Hata Nobuhiro、Suzuki Satoshi O、Yoshimoto Koji、Arimura Koichi、Amemiya Takeo、Akagi Yojiro、Kuga Daisuke、Oba Utako、Koga Yuhki、Ohga Shouichi、Iwaki Toru、Iihara Koji
- Journal Title
  
  Neuropathology
  
  Volume: in press Issue: 4 Pages: 422-427
- DOI
  10.1111/neup.12471
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779
[Journal Article] Treatment Strategy for Tuberculum Sellae Meningiomas Based on a Preoperative Radiological Assessment2018
- Author(s)
  Kuga Daisuke、Toda Masahiro、Yoshida Kazunari
- Journal Title
  
  World Neurosurgery
  
  Volume: 120 Pages: 1279-1288
- DOI
  10.1016/j.wneu.2018.09.054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08970, KAKENHI-PROJECT-18K19622
[Journal Article] The effectiveness of salvage treatments for recurrent lesions of oligodendrogliomas previously treated with upfront chemotherapy2018
- Author(s)
  Kuga Daisuke、Hata Nobuhiro、Akagi Yojiro、Amemiya Takeo、Sangatsuda Yuhei、Hatae Ryusuke、Yoshimoto Koji、Mizoguchi Masahiro、Iihara Koji
- Journal Title
  
  World Neurosurgery
  
  Volume: in press Pages: e735-e742
- DOI
  10.1016/j.wneu.2018.03.069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-18K08970
[Journal Article] Reclassification of 400 consecutive glioma cases based on the revised 2016WHO classification.2018
- Author(s)
  Akagi Y, Yoshimoto K, Hata N, Kuga D, Hatae R, Amemiya T, Sangatsuda Y, Suzuki SO, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Brain tumor pathology
  
  Volume: 35 Issue: 2 Pages: 81-89
- DOI
  10.1007/s10014-018-0313-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K20015, KAKENHI-PROJECT-18K08970, KAKENHI-PROJECT-16K10779
[Journal Article] An elderly case of malignant small cell glioma with hemorrhage coexistent with a calcified pilocytic astrocytoma component in the cerebellar hemisphere2018
- Author(s)
  Sangatsuda Yuhei、Hata Nobuhiro、Suzuki Satoshi O.、Akagi Yojiro、Hatae Ryusuke、Kuga Daisuke、Yoshimoto Koji、Momosaki Seiya、Iwaki Toru、Iihara Koji
- Journal Title
  
  Neuropathology
  
  Volume: 38 Issue: 5 Pages: 493-497
- DOI
  10.1111/neup.12478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779
[Journal Article] Measurement of the perfusion fraction in brain tumors with intravoxel incoherent motion MR imaging: validation with histopathological vascular density in meningiomas2018
- Author(s)
  Togao Osamu、Hiwatashi Akio、Yamashita Koji、Kikuchi Kazufumi、Momosaka Daichi、Yoshimoto Koji、Kuga Daisuke、Mizoguchi Masahiro、Suzuki Satoshi O、Iwaki Toru、Van Cauteren Marc、Iihara Koji、Honda Hiroshi
- Journal Title
  
  The British Journal of Radiology
  
  Volume: 91 Issue: 1085 Pages: 20170912-20170912
- DOI
  10.1259/bjr.20170912
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08970
[Journal Article] Endoscopic endonasal approach combined with a simultaneous transcranial approach for giant pituitary tumors.2018
- Author(s)
  Kuga D, Toda M, Ozawa H, Ogawa K, Yoshida K
- Journal Title
  
  World Neurosurgery
  
  Volume: 121 Pages: 173-179
- DOI
  10.1016/j.wneu.2018.10.047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19622, KAKENHI-PROJECT-18K08970
[Journal Article] Amide proton transfer imaging to predict tumor response to neoadjuvant chemotherapy in locally advanced rectal cancer2018
- Author(s)
  Nishie Akihiro、Asayama Yoshiki、Ishigami Kousei、Ushijima Yasuhiro、Takayama Yukihisa、Okamoto Daisuke、Fujita Nobuhiro、Tsurumaru Daisuke、Togao Osamu、Sagiyama Koji、Manabe Tatsuya、Oki Eiji、Kubo Yuichiro、Hida Tomoyuki、Hirahashi-Fujiwara Minako、Keupp Jochen、Honda Hiroshi
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 34 Issue: 1 Pages: 140-146
- DOI
  10.1111/jgh.14315
- Data Source
  KAKENHI-PROJECT-17K10410
[Journal Article] Amide proton transfer (APT) magnetic resonance imaging of endometrioid endometrial adenocarcinoma: association with histologic grade.2018
- Author(s)
  Yukihisa Takayama, Akihiro Nishie, Osamu Togao, Yoshiki Asayama, Kousei Ishigami, Yasuhiro Ushijima, Daisuke Okamoto, Nobuhiro Fujita, Kenzo Sonoda, Tomoyuki Hida, Yoshihiro Ohishi, Jochen Keupp, Hiroshi Honda.
- Journal Title
  
  Radiology
  
  Volume: 286 Issue: 3 Pages: 909-917
- DOI
  10.1148/radiol.2017170349
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11281, KAKENHI-PROJECT-17K10410
[Journal Article] High-resolution melting and immunohistochemical analysis efficiently detects mutually exclusive genetic alterations of adamantinomatous and papillary craniopharyngiomas2017
- Author(s)
  Yoshimoto Koji、Hatae Ryusuke、Suzuki Satoshi O.、Hata Nobuhiro、Kuga Daisuke、Akagi Yojiro、Amemiya Takeo、Sangatsuda Yuhei、Mukae Nobutaka、Mizoguchi Masahiro、Iwaki Toru、Iihara Koji
- Journal Title
  
  Neuropathology
  
  Volume: 38 Issue: 1 Pages: 3-10
- DOI
  10.1111/neup.12408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Prevalence and clinicopathological features of H3.3 G34-mutant high-grade gliomas: a retrospective study of 411 consecutive glioma cases in a single institution.2017
- Author(s)
  Yoshimoto K, Hatae R, Sangatsuda Y, Suzuki SO, Hata N, Akagi Y, Kuga D, Hideki M, Yamashita K, Togao O, Hiwatashi A, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Brain Tumor Pathol.
  
  Volume: 印刷中 Issue: 3 Pages: 103-112
- DOI
  10.1007/s10014-017-0287-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Diagnostic Utility of Intravoxel Incoherent Motion MR imaging in Differentiating Primary Central Nervous System Lymphoma from Glioblastoma Multiforme2016
- Author(s)
  .Yamashita K, Hiwatashi A, Togao O, et al.
- Journal Title
  
  J Magn Reson Imaging.
  
  Volume: 44(5) Issue: 5 Pages: 1256-1261
- DOI
  10.1002/jmri.25261
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461828, KAKENHI-PROJECT-16K20015
[Journal Article] A comprehensive analysis identifies BRAF hotspot mutations associated with gliomas with peculiar epithelial morphology.2016
- Author(s)
  Hatae R, Hata N, Suzuki SO, Yoshimoto K, Kuga D, Murata H, Akagi Y, Sangatsuda Y, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Neuropathology
  
  Volume: 28 Issue: 3 Pages: 191-199
- DOI
  10.1111/neup.12347
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Add-on bevacizumab can prevent early clinical deterioration and prolong survival in newly diagnosed partially resected glioblastoma patients with a poor performance status.2016
- Author(s)
  Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Shono T, Mizoguchi M, Iihara K.
- Journal Title
  
  Onco Targets Ther.
  
  Volume: 10 Pages: 429-437
- DOI
  10.2147/ott.s125587
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Deferred radiotherapy and upfront procarbazine-ACNU-vincristine administration for 1p19q codeleted oligodendroglial tumors are associated with favorable outcome without compromising patient performance, regardless of WHO grade.2016
- Author(s)
  Hata N, Yoshimoto K, Hatae R, Kuga D, Akagi Y, Suzuki SO, Iwaki T, Shono T, Mizoguchi M, Iihara K.
- Journal Title
  
  Onco Targets Ther.
  
  Volume: 9 Pages: 7123-7131
- DOI
  10.2147/ott.s115911
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Insular primary glioblastomas with IDH mutations: Clinical and biological specificities.2016
- Author(s)
  Hata N, Hatae R, Yoshimoto K, Murata H, Kuga D, Akagi Y, Sangatsuda Y, Suzuki SO, Iwaki T, Mizoguchi M, Iihara K.
- Journal Title
  
  Neuropathology
  
  Volume: 24 Issue: 3 Pages: 200-207
- DOI
  10.1111/neup.12362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15529, KAKENHI-PROJECT-16K10779, KAKENHI-PROJECT-16K20015
[Journal Article] Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data.2016
- Author(s)
  Hatae R, Hata N, Yoshimoto K, Kuga D, Akagi Y, Murata H, Suzuki SO, Mizoguchi M, Iihara K.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 8 Pages: e0160489-e0160489
- DOI
  10.1371/journal.pone.0160489
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 成人IDH野生型diffuse gliomaの手術と臨床像2023
- Author(s)
  藤岡寛、三月田祐平、空閑太亮、尾辻亮介、野口直樹、秦暢宏、中溝玲、溝口昌弘、吉本幸司
- Organizer
  第28回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] Oligodendrogliomaに対するACNUの有効性:分子診断による治療層別化の長期成績2023
- Author(s)
  尾辻亮介、秦暢宏、野口直樹、藤岡寛、三月田祐平、空閑太亮、中溝玲:、溝口昌弘、吉本幸司
- Organizer
  第41回　日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] WHO2021に対応した in-house分子診断：先進医療体制における現状と課題2023
- Author(s)
  秦暢宏, 藤岡寛, 佐古亜紀, 空閑太亮, 三月田祐平, 尾辻亮介, 野口直樹, 溝口昌弘, 藤木稔, 吉本幸司
- Organizer
  第41回日本脳腫瘍病理学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] Oligodendrogliomaに対する治療戦略：分子層別化による長期成績の検討2023
- Author(s)
  秦暢宏, 尾辻亮介, 空閑太亮, 三月田祐平, 藤岡寛, 溝口昌弘, 吉本幸司
- Organizer
  第28回日本脳腫瘍の外科学会 2023年9月30日
- Data Source
  KAKENHI-PROJECT-23K08545
[Presentation] 先進医療制度によるWHO新分類に対応した diffuse gliomaの in-house分子診断2023
- Author(s)
  秦暢宏, 藤岡寛, 佐古亜紀, 空閑太亮, 三月田祐平, 尾辻亮介, 野口直樹, 溝口昌弘, 藤木稔, 吉本幸司
- Organizer
  第82回日本脳神経外科学会 2023年10月25日
- Data Source
  KAKENHI-PROJECT-23K08545
[Presentation] Oligodendrogliomaに対する治療戦略：分子層別化による長期成績の検討2023
- Author(s)
  秦暢宏, 尾辻亮介, 空閑太亮, 三月田祐平, 藤岡寛, 溝口昌弘, 吉本幸司
- Organizer
  第28回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 繰り返すWHO改定にどう対応すべきか？：先進医療制度によるin-house分子診断体制2023
- Author(s)
  秦暢宏、藤岡寛、尾辻亮介、空閑太亮、波多江龍亮、三月田祐平、雨宮健生、野口直樹、佐古亜紀、藤木稔、溝口昌弘、吉本幸司
- Organizer
  第41回　日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 髄液 cell-free DNA を用いたMLPA法によるコピー数解析2023
- Author(s)
  尾辻亮介, 藤岡寛, 秦暢宏, 野口直樹, 三月田祐平, 空閑太亮, 中溝玲, 山元英崇, 溝口昌弘, 吉本幸司
- Organizer
  第41回日本脳腫瘍病理学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] Outcome impact of the CDKN2A/B hemizygous deletion in IDH-mutant astrocytoma2023
- Author(s)
  Ryosuke Otsuji，Nobuhiro Hata，Hidetaka Yamamoto, Daisuke Kuga，Yuhei Sangatsuda，Yutaka Fujioka，Naoki Noguchi，Akira Nakamizo，Masahiro Mizoguchi, Koji Yoshimoto
- Organizer
  28th Annual Meeting and Education Day of the Society for Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 当院におけるがんパネル検査と治療に至った症例の臨床的経過2023
- Author(s)
  藤岡寛、尾辻亮介、野口直樹:、空閑太亮、秦暢宏、中溝玲、溝口昌弘、吉本幸司
- Organizer
  第41回　日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] がんゲノム医療時代の新たな脳腫瘍治療戦略2023
- Author(s)
  溝口昌弘、藤岡寛、尾辻亮介、三月田祐平、空閑太亮、秦暢宏、古賀友紀、吉本幸司
- Organizer
  日本脳神経外科学会　第82回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫に対する積極的摘出の意義：volumetric解析による検証2022
- Author(s)
  秦暢宏;尾辻亮介;三月田祐平;藤岡寛;瀧川浩介;舟越勇介;空閑太亮;中溝玲;溝口昌弘;吉本幸司
- Organizer
  第81回日本脳神経外科学会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] Diffuse gliomaに対する髄液中cell free DNAを用いたliquid biopsyの現状と課題2022
- Author(s)
  藤岡寛, 尾辻亮介, 舟越勇介, 瀧川浩介, 三月田祐平, 空閑太亮, 秦暢宏, 中溝玲, 溝口昌弘, 吉本幸司
- Organizer
  一般社団法人日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫に対する拡大的摘出は予後を改善するか？2022
- Author(s)
  秦暢宏;尾辻亮介;三月田祐平;藤岡寛;瀧川浩介;舟越勇介;空閑太亮;中溝玲;溝口昌弘;吉本幸司
- Organizer
  第27回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] IDH-mutant神経膠腫におけるCDKN2A/B欠失の予後への影響2022
- Author(s)
  尾辻亮介，秦暢宏，三月田祐平，藤岡寛，瀧川浩介，舟越勇介，野口直樹, 空閑　太亮，中溝　玲，溝口昌弘, 吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 当院におけるRosette-forming glioneuronal tumorの経験2022
- Author(s)
  藤岡寛、瀧川浩介、三月田祐平、空閑太亮、秦暢宏、溝口昌弘、吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] IDH-mutant神経膠腫におけるCDKN2A/B欠失の予後への影響2022
- Author(s)
  尾辻亮介，秦暢宏，三月田祐平，藤岡寛，瀧川浩介，舟越勇介，野口直樹, 空閑　太亮，中溝　玲，溝口昌弘, 吉本幸司
- Organizer
  一般社団法人日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] ヒト血液由来誘導ミクログリア様細胞の貪食能についての検討2022
- Author(s)
  前原直喜, 白水寛理, 田中俊也, 扇谷昌宏, 三月田祐平, 藤岡寛, 空閑太亮, 秦暢宏, 溝口昌弘, 加藤隆弘, 吉本幸司
- Organizer
  一般社団法人日本脳神経外科学会第81回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 当院のMicrosatellite instabilityを有するGBMにおける遺伝的および免疫学的プロファイルの検討2021
- Author(s)
  瀧川浩介, 波多江龍亮, 三木健嗣, 尾辻亮介, 舟越勇介, 藤岡寛, 三月田祐平, 空閑太亮秦暢宏, 溝口昌弘, 吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫におけるsupra-maximal resection の予後への影響2021
- Author(s)
  尾辻亮介,秦暢宏,舟越勇介,溝口昌弘,空閑太亮,三月田祐平, 藤岡寛, 瀧川浩介, 吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫におけるsupra-maximal resection の予後への影響2021
- Author(s)
  尾辻亮介,秦暢宏,舟越勇介,溝口昌弘,空閑太亮,三月田祐平, 藤岡寛, 瀧川浩介, 吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 1p19q co-del oligodendrogliomaに対するPAVの有効性：分子診断による治療層別化の長期成績2021
- Author(s)
  秦暢宏、溝口昌弘、空閑太亮、三月田祐平、藤岡寛、瀧川浩介、舟越勇介、尾辻亮介、吉本幸司
- Organizer
  第80回日本脳神経外科学会総会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] Current Trend in Treatment of Glioblastoma in Japan: A National Survey Using the Diagnostic Procedure Combination Database (J-ASPECT Study-Glioblastoma)2021
- Author(s)
  Nobuhiro Hata1), Yusuke Funakoshi1), Daisuke Kuga1), Yuhei Sangatsuda1), Yutaka Fujioka1), Kosuke Takigawa1), Koji Yoshimoto1), Masahiro Mizoguchi1), Koji Iihara2)
- Organizer
  The 39th Annual Meeting of the Japan Society for Neuro-Oncology
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] Diffuse midline gliomaに対するcell free DNAを用いたliquid biopsy2021
- Author(s)
  藤岡寛、尾辻亮介、舟越勇介、瀧川浩介、三月田祐平、空閑太亮秦　暢宏、溝口昌弘、吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 初発脳腫瘍における髄液中cell free DNA量の検討2021
- Author(s)
  藤岡寛, 尾辻亮介, 舟越勇介, 瀧川浩介, 三月田祐平, 空閑太亮, 秦暢宏, 溝口昌弘吉本幸司
- Organizer
  第39回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 脳腫瘍に対するがんゲノム医療の現状と展望2021
- Author(s)
  溝口昌弘、秦暢宏、空閑太亮、三月田裕平、藤岡寛、瀧川浩介、舟越勇介
- Organizer
  第29回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 膠芽腫はどこまで摘出すべきか？volumetric解析による検証2021
- Author(s)
  秦暢宏、溝口昌弘，尾辻亮介，舟越勇介，空閑太亮，三月田祐平，藤岡寛，瀧川浩介，吉本幸司
- Organizer
  第26回日本脳腫瘍の外科学会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] がんゲノム医療時代のグリオーマ治療戦略2021
- Author(s)
  溝口昌弘、秦暢宏、空閑太亮、三月田裕平、藤岡寛、瀧川浩介、舟越勇介、吉本幸司
- Organizer
  日本脳神経外科学会第80回学術総会
- Data Source
  KAKENHI-PROJECT-21H03044
[Presentation] 髄液中cell free tumor DNAを用いたDiffuse gliomaの分子診断2020
- Author(s)
  藤岡寛、秦　暢宏、空閑太亮、赤木洋二郎、波多江龍亮、三月田祐平、瀧川浩介、舟越勇介、溝口昌弘.
- Organizer
  日本脳神経外科学会第78回学術総会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] 髄液中cell free DNA解析によるdiffuse gliomaの分子診断2020
- Author(s)
  藤岡寛, 秦暢宏, 空閑太亮, 波多江龍亮, 三月田祐平, 瀧川浩介, 舟越勇介, 溝口昌弘
- Organizer
  第37回日本脳腫瘍学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09392
[Presentation] The correlation between 1p19q and TERT promoter mutation status in IDH-mutant gliomas2018
- Author(s)
  Nobuhiro Hata, Masahiro MIizoguchi, Yojiro Akagi, Satoshi O Suzuki, Daisuke Kuga, Takeo Amemiya, Ryusuke Hatae, Koji Yoshimoto, Toru Iwaki, Koji Iihara
- Organizer
  The 19th International Congress of Neuropathology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 高解像度融解曲線の２階微分解析による、グリオーマ点変異の高精度判定：HRM-MI法2017
- Author(s)
  秦暢宏、波多江龍亮、吉本幸司、空閑大亮、雨宮健生、赤木洋二郎、三月田祐平、溝口昌弘、飯原弘二
- Organizer
  日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] Clinical significance of salvage surgery for recurrent IDH-mutant and 1p/19q codeleted oligodendroglial tumor2017
- Author(s)
  空閑太亮、秦暢宏、吉本幸司、波多江　龍亮、赤木洋二郎、溝口昌弘、飯原弘二
- Organizer
  The 14th meeting of the asian society for neuro-oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K20015
[Presentation] 改良HRM解析法による、高精度なグリオーマ分子診断法の開発2017
- Author(s)
  秦暢宏、波多江龍亮、吉本幸司、空閑大亮、赤木洋二郎、三月田祐平、鈴木諭、岩城徹、溝口昌弘、飯原弘二
- Organizer
  日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 膠芽腫におけるギリアデル留置後の再発形式および病理学的変化の検討2017
- Author(s)
  空閑太亮、赤木洋二郎、秦暢宏、吉本幸司、溝口昌弘、鈴木諭、飯原弘二
- Organizer
  第35回日本脳腫瘍病理学会
- Data Source
  KAKENHI-PROJECT-16K20015
[Presentation] 1p19q co-deletionを有する oligodendrogliomaに対するPAV先行治療：分子診断による治療層別化の長期成績2017
- Author(s)
  秦暢宏、吉本幸司、空閑太亮、波多江龍亮、赤木洋二郎、鈴木諭、岩城徹、溝口昌弘、飯原弘二
- Organizer
  第34回日本脳腫瘍病理学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] IDH mutant, 1p/19q codeletd Oligodendroglial tumorの長期予後2016
- Author(s)
  空閑太亮　秦暢宏　吉本幸司　波多江龍亮　赤木洋二郎　溝口昌弘　佐山徹郎　飯原　弘二
- Organizer
  第34回日本脳腫瘍学会
- Place of Presentation
  山梨県　甲府市
- Data Source
  KAKENHI-PROJECT-16K20015
[Presentation] 初発膠芽腫に対するBevacizumab承認後の新規治療戦略：現況と展望2016
- Author(s)
  秦暢宏、吉本幸司、溝口昌弘、波多江龍亮、赤木洋二郎、三月田祐平、空閑太亮、庄野禎久、飯原弘二
- Organizer
  第75回日本脳神経外科学会総会
- Place of Presentation
  福岡県　福岡市
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] Deferred Radiotherapy and Upfront Procarbazine-ACNU-Vincristine Administration for 1p19q Codeleted Oligodendroglial Tumors is Associated with Favorable Outcome without Compromising Patient Performance, Regardless of WHO Grade2016
- Author(s)
  Nobuhiro HATA, Koji YOSHIMOTO, Daisuke KUGA, Ryusuke HATAE, Yojiro AKAGI, Satoshi O SUZUKI, Toru IWAKI, Masahiro MIZOGUCHI, Koji IIHARA
- Organizer
  The 14th Young-Honam and Kyushu Neurosurgical Joint Meeting
- Place of Presentation
  福岡県　福岡市
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10779
[Presentation] 初発神経膠芽腫に対するBevacizumab併用療法の治療成績2016
- Author(s)
  秦暢宏、吉本幸司、空閑太亮、波多江龍亮、赤木洋二郎、三月田祐平、溝口昌弘、、飯原弘二
- Organizer
  第34回日本脳腫瘍学会
- Place of Presentation
  山梨県　甲府市
- Data Source
  KAKENHI-PROJECT-16K10779

1. Hata Nobuhiro (10596034)

# of Collaborated Projects: 6 results

# of Collaborated Products: 51 results
2. Yoshimoto Koji (70444784)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
3. Mizoguchi Masahiro (50380621)

# of Collaborated Projects: 4 results

# of Collaborated Products: 43 results
4. 三月田祐平 (00848640)

# of Collaborated Projects: 4 results

# of Collaborated Products: 37 results
5. TOGAO OSAMU (10452749)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
6. 樋渡昭雄 (30444855)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
7. 飯原弘二 (90270727)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. 西村中 (90452755)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 山下孝二 (80546565)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 本田浩 (90145433)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 赤木洋二郎 (10570773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. 藤岡寛 (10914252)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
13. Sayama Tetsuro (30346788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 迎伸孝 (60532843)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 橋口公章 (80448422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 森恩 (90448415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 平田秀成 (90721267)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 波多江龍亮 (20570774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
19. 加藤隆弘 (70546465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 扇谷昌宏 (60636455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 中溝玲 (80529800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
22. 札場博貴 (00772930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 籾井泰朋 (20534192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. SONODA、KENZOU

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 戸田正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUGA DAISUKE 空閑 太亮

Kuga Daisuke 空閑 太亮

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Epigenetic Analysis of Blood cfDNA in Pituitary Adenomas and Clinical ApplicationsPrincipal Investigator

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Development of an innovative diagnostic / therapeutic system for intracranial germ cell tumorsPrincipal Investigator

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Detection of blood biomarker in the patients' with Bevacizumab treated glioblastomasPrincipal Investigator

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[Journal Article] In‐house molecular diagnosis of diffuse glioma updating the revised <scp>WHO</scp> classification by a platform of the advanced medical care system, <scp>Senshin‐Iryo</scp>2024

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[Journal Article] Liquid Biopsy for Glioma Using Cell-Free DNA in Cerebrospinal Fluid2024

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[Journal Article] Supramaximal Resection Can Prolong the Survival of Patients with Cortical Glioblastoma: A Volumetric Study2023

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KUGA DAISUKE 空閑太亮

Kuga Daisuke 空閑太亮