Iwasaki Takeshi 岩崎健

Researcher Number	40766185
Other IDs
Affiliation (Current)	2025: 九州大学, 大学病院, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 九州大学, 大学病院, 准教授 2022: 九州大学, 九州大学病院, 准教授 2021: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 49020:Human pathology-related / 0901:Oncology and related fields Except Principal Investigator Basic Section 49020:Human pathology-related / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 腫瘍内不均一性 / メルケル細胞ポリオーマウイルス / メルケル細胞癌 / RNA修飾 / 網羅的解析 / エピトランスクリプトーム / RNAメチル化 / 骨軟部腫瘍 / 軟部肉腫 Except Principal Investigator エビジェネティクス … More / マルチオミクス / 骨軟部腫瘍 / 希少癌 / 腫瘍代謝 / 腫瘍免疫 / 腫瘍微小環境 / 空間的プロテオーム / 肝硬変 / 線維化 / 右心不全 / 三次リンパ組織様構造 (TLS) / メルケル細胞癌 / ヒストン / エピジェネティクス / 次世代シーケンサー / SMARCB1欠失軟部腫瘍 / 悪性抹消神経鞘腫 / 骨原発未分化多形肉腫 / 軟骨芽細胞腫 / 粘液脂肪肉腫 / 未分化多形肉腫 / ヒストンH3 / ヒストン修飾 / 悪性骨巨細胞腫 / エピゲノム Less

メルケル細胞癌のエピトランスクリプトーム制御の破綻がもたらす腫瘍免疫環境の解明Principal Investigator
- Principal Investigator
  
  岩崎健
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyushu University
メルケル細胞癌の疲弊T細胞とTLS構成細胞に基づく治療効果予測・耐性機構の解明
- Principal Investigator
  
  松下倫子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Tottori University
Elucidating the Mechanisms and Reversibility of Congestive Hepatic Fibrosis in Right Heart Failure Using Multimodality Approaches
- Principal Investigator
  
  山村健一郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
空間的マルチオミクス解析による軟部肉腫の腫瘍微小環境の解明と代謝標的治療法の探索
- Principal Investigator
  
  小田義直
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyushu University
シングルセル時空間マルチオミクス解析によるメルケル細胞癌の病態解明Principal Investigator
- Principal Investigator
  
  岩崎健
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyushu University
Epitranscriptomic alteration in soft tissue sarcomaPrincipal Investigator
- Principal Investigator
  
  Iwasaki Takeshi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kyushu University
Multi-omics analysis of the mechanisms of tumorigenesis and acquired treatment resistance in rare cancer, sarcoma
- Principal Investigator
  
  Oda Yoshinao
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation Book

[Book] がんゲノム医療時代の分子腫瘍学病理と臨床 2022年臨時増刊号（40巻）2022
- Author(s)
  岩崎健, 山元範昭, 小田義直 (分担執筆)
- Total Pages
  424
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-21K20805
[Journal Article] Prognostic value of nuclear morphometry in myxoid liposarcoma2023
- Author(s)
  Kawaguchi Kengo、Kohashi Kenichi、Iwasaki Takeshi、Yamamoto Takeo、Ishihara Shin、Toda Yu、Yamamoto Hidetaka、Nakashima Yasuharu、Oda Yoshinao
- Journal Title
  
  Cancer Science
  
  Volume: - Issue: 5 Pages: 2178-2188
- DOI
  10.1111/cas.15729
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K20805, KAKENHI-PROJECT-21K06887, KAKENHI-PROJECT-23K27385
[Journal Article] Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma2023
- Author(s)
  Iwasaki Takeshi、Hayashi Kazuhiko、Matsushita Michiko、Nonaka Daisuke、Matsumoto Takamasa、Taniguchi Midori、Kuwamoto Satoshi、Umekita Yoshihisa、Oda Yoshinao
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 13114-13114
- DOI
  10.1038/s41598-023-40050-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K15406, KAKENHI-PROJECT-21K06885
[Journal Article] Expression of SATB2, RUNX2, and SOX9 and possible osteoblastic and chondroblastic differentiation in chondroblastoma2023
- Author(s)
  Toda Yu、Yamamoto Hidetaka、Iwasaki Takeshi、Ishihara Shin、Ito Yoshihiro、Susuki Yosuke、Kawaguchi Kengo、Kinoshita Izumi、Kiyozawa Daisuke、Yamada Yuichi、Kohashi Kenichi、Kimura Atsushi、Fujiwara Toshifumi、Setsu Nokitaka、Endo Makoto、Matsumoto Yoshihiro、Nakashima Yasuharu、Mawatari Masaaki、Oda Yoshinao
- Journal Title
  
  Pathology - Research and Practice
  
  Volume: 241 Pages: 154239-154239
- DOI
  10.1016/j.prp.2022.154239
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K06941, KAKENHI-PROJECT-22K09359, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-18K16626
[Journal Article] Histological background of dedifferentiated solitary fibrous tumour2022
- Author(s)
  Yamada Y, Kohashi K, Kinoshita I, Yamamoto H, Iwasaki , Koga Y, Hashisako M, Kiyozawa D, Kitahara D, Narutomi F, Kuboyama Y, Nakamura T, Toyokawa G, Tsuchihashi K, Fushimi F, Taguchi K, Nishiyama K, Tamiya S, Oshiro Y, Furue M, Nakashima Y, Suzuki S, Iwaki T, Oda Y.
- Journal Title
  
  Journal of Clinical Pathology
  
  Volume: 75 Issue: 6 Pages: 397-403
- DOI
  10.1136/jclinpath-2020-207311
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03444
[Journal Article] Cyclin-dependent kinase 8 is an independent prognosticator in uterine leiomyosarcoma2022
- Author(s)
  Yasutake Nobuko、Iwasaki Takeshi、Yamamoto Hidetaka、Sonoda Kenzo、Kodama Keisuke、Okugawa Kaoru、Asanoma Kazuo、Yahata Hideaki、Kato Kiyoko、Oda Yoshinao
- Journal Title
  
  Pathology - Research and Practice
  
  Volume: 235 Pages: 153920-153920
- DOI
  10.1016/j.prp.2022.153920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09519, KAKENHI-PROJECT-22K19604, KAKENHI-PROJECT-19H03444
[Journal Article] Myxoid type and non-myxoid type of intimal sarcoma in large vessels and heart: review of histological and genetic profiles of 20 cases2022
- Author(s)
  Yamada Yuichi、Fukushima Mana（３１名中２７番目）
- Journal Title
  
  Virchows Archiv
  
  Volume: 480 Issue: 4 Pages: 919-925
- DOI
  10.1007/s00428-022-03293-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16173, KAKENHI-PROJECT-21K06887, KAKENHI-PROJECT-22K19438, KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-20H03719
[Journal Article] Clinical significance of signal regulatory protein alpha and T cell immunoreceptor with immunoglobulin and immunoreceptor tyrosine-based inhibition motif domain expression in undifferentiated pleomorphic sarcoma2022
- Author(s)
  Ishihara Shin、Iwasaki Takeshi、Kohashi Kenichi、Kawaguchi Kengo、Toda Yu、Fujiwara Toshifumi、Setsu Nokitaka、Endo Makoto、Matsumoto Yoshihiro、Nakashima Yasuharu、Oda Yoshinao
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 1 Issue: 6 Pages: 1-1
- DOI
  10.1007/s00432-022-04078-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09325, KAKENHI-PROJECT-22K09359, KAKENHI-PROJECT-18K16626, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-19K16802, KAKENHI-PROJECT-21K20805, KAKENHI-PROJECT-23K08700, KAKENHI-PROJECT-23K27385
[Journal Article] 婦人科領域に発生した悪性度の異なる血管周囲類上皮細胞腫瘍の2症例2022
- Author(s)
  安部拓也，岩崎健，井手圭一郎，立岩友美，奥薗学，豊嶋憲子，笹栗毅和，木下伊寿美, 本下潤一
- Journal Title
  
  日本臨床細胞学会雑誌
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K20805
[Journal Article] PD-L1 and IDO-1 expression in undifferentiated pleomorphic sarcoma: The associations with tumor infiltrating lymphocytes, dMMR and HLA class I.2021
- Author(s)
  Ishihara S, Yamada Y, Iwasaki T, Yoshimoto M, Toda Y, Kohashi K, Yamamoto H, Matsumoto Y, Nakashima Y, Oda Y.
- Journal Title
  
  Oncol Rep.
  
  Volume: 45 Issue: 1 Pages: 379-389
- DOI
  10.3892/or.2020.7837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-18K09067, KAKENHI-PROJECT-17K15645, KAKENHI-PROJECT-21K06887
[Journal Article] Histological and immunohistochemical features and genetic alterations in the malignant progression of giant cell tumor of bone: a possible association with TP53 mutation and loss of H3K27 trimethylation2021
- Author(s)
  Ishihara Shin、Yamamoto Hidetaka、Iwasaki Takeshi、Toda Yu、Yamamoto Takeo、Yoshimoto Masato、Ito Yoshihiro、Susuki Yousuke、Kawaguchi Kengo、Kinoshita Izumi、Yamada Yuichi、Kohashi Kenichi、Fujiwara Toshifumi、Setsu Nokitaka、Endo Makoto、Matsumoto Yoshihiro、Kakuda Yuko、Nakashima Yasuharu、Oda Yoshinao
- Journal Title
  
  Modern Pathology
  
  Volume: - Issue: 5 Pages: 640-648
- DOI
  10.1038/s41379-021-00972-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09325, KAKENHI-PROJECT-18K16626, KAKENHI-PROJECT-18K16627, KAKENHI-PROJECT-21K06887, KAKENHI-PROJECT-22K06941, KAKENHI-PROJECT-19H03444
[Journal Article] Association of PD-L1 and IDO1 expression with JAK?STAT pathway activation in soft-tissue leiomyosarcoma2021
- Author(s)
  Iwasaki Takeshi、Kohashi Kenichi、Toda Yu、Ishihara Shin、Yamada Yuichi、Oda Yoshinao
- Journal Title
  
  Journal of Cancer Research and Clinical Oncology
  
  Volume: 147 Issue: 5 Pages: 1451-1463
- DOI
  10.1007/s00432-020-03390-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-21K06887
[Journal Article] PD-L1 and IDO1 expression and tumor-infiltrating lymphocytes in osteosarcoma patients: comparative study of primary and metastatic lesions2020
- Author(s)
  Toda Y, Kohashi K, Yamada Y, Yoshimoto M, Ishihara S, Ito Y, Iwasaki T, Yamamoto H, Matsumoto Y, Nakashima Y, Mawatari M, Oda Y.
- Journal Title
  
  J Cancer Res Clin Oncol.
  
  Volume: 146 Issue: 10 Pages: 2607-2620
- DOI
  10.1007/s00432-020-03242-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-18K09067
[Journal Article] Frequent MN1 gene mutations in malignant peripheral nerve sheath tumor.2020
- Author(s)
  Kinoshita I, Yamada Y, Kohashi K, Yamamoto H, Iwasaki T, Ishihara S, Toda YU, Ito Y, Susuki Y, Kawaguchi K, Ichiki T, Sato Y, Furue M, Nakashima Y, Oda Y.
- Journal Title
  
  Anticancer Res.
  
  Volume: 40 Issue: 11 Pages: 6221-6228
- DOI
  10.21873/anticanres.14642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03444, KAKENHI-PROJECT-17K15645
[Journal Article] Clinicopathological review of solitary fibrous tumors: dedifferentiation is a major cause of patient death.2019
- Author(s)
  Yamada Y, Kohashi K, Kinoshita I, et al.
- Journal Title
  
  Virchows Arch
  
  Volume: 2019 Oct;475 Issue: 4 Pages: 467-477
- DOI
  10.1007/s00428-019-02622-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15645, KAKENHI-PROJECT-19H03444
[Presentation] 軟骨肉腫におけるDNAメチル化異常と予後予測因子の解析2024
- Author(s)
  古川寛、岩崎健、川口健悟、園田裕樹、孝橋賢一、山元英崇、小田義直
- Organizer
  第113回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K27385
[Presentation] メルケル細胞癌におけるFOXP3,TIGIT/CD155経路の異常発現と臨床病態の解明2023
- Author(s)
  岩崎健 , 林一彦松下倫子 , 松本崇雅, 宮本拓海 , 大石智恵美, 桑本聡史 , 梅北善久, 小田義直
- Organizer
  日本病理学会総会
- Data Source
  KAKENHI-PROJECT-22K15406
[Presentation] 卵巣癌肉腫におけるクロマチンリモデリング変異および遺伝子発現と予後解析2023
- Author(s)
  片山由大、岩崎健、古川寛、曲淵直未、小田義直
- Organizer
  第82回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27385
[Presentation] 骨軟部腫瘍の診断と治療に関連した遺伝子異常と腫瘍微小環境研究の現状と展望2023
- Author(s)
  岩崎健、小田義直
- Organizer
  第112回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-23K27385
[Presentation] 高悪性度脂肪肉腫におけるperilipin1およびadipophilinタンパク質発現の予後的意義2023
- Author(s)
  川口健悟、孝橋賢一、毛利太郎、岩崎健、木下伊寿美、薄陽祐、古川寛、佐藤ちあ紀、園田裕樹、中島康晴、小田義直
- Organizer
  56回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-23K27385
[Presentation] 悪性骨巨細胞腫の組織と遺伝子変異の検討－TP53遺伝子変異とH3K27me3 の消失に関して－2022
- Author(s)
  石原新、山元英崇、岩崎健、戸田雄、孝橋賢一、藤原稔史、薛宇孝、遠藤誠、松本嘉寛、中島康晴、小田義直
- Organizer
  第55回日本整形外科学会骨・軟部腫瘍学術集会
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] 粘液型脂肪肉腫における予後予測ツールとしての新規核異形度分類の提案とその分子遺伝学的背景の検討2022
- Author(s)
  川口健悟、孝橋賢一、石原新、戸田雄、岩崎健、山本猛雄、遠藤誠、松本嘉寛、小田義直
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] Epitranscriptomic controls in soft-tissue leiomyosarcoma2022
- Author(s)
  Takeshi Iwasaki, Takemasa Matsumoto, Toshio Ichiki, Kenichi Kohashi, Yoshinao Oda
- Organizer
  第81回　日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-21K20805
[Presentation] エピトランスクリプトミクス異常からみた軟部平滑筋肉腫の病態解明2022
- Author(s)
  岩崎健、松本崇雅、一木稔生、孝橋賢一、小田義直
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] NTRK融合遺伝子陽性腫瘍の病理診断2021
- Author(s)
  孝橋賢一、木下伊寿美、岩崎健、山元英崇、小田義直
- Organizer
  第63回日本小児血液・がん学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] 軟部平滑筋肉腫におけるPD-L1、IDO1発現とJak-Stat経路の活性化に関する検討2020
- Author(s)
  岩崎健、山田裕一、石原新、戸田雄、孝橋賢一、小田義直
- Organizer
  第109回日本病理学会総会オンライン総会
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] 骨肉腫におけるPDL1とIDO1の発現2019
- Author(s)
  戸田雄、孝橋賢一、山田裕一、吉本昌人、石原新、伊東良広、岩崎健、山元英崇、藤原稔史、薛宇孝、遠藤誠、松本嘉寛、中島康晴、馬渡正明、小田義直
- Organizer
  日本整形外科学会骨・軟部腫瘍学術総会
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] 未分化多形肉腫におけるPD-L1とIDO-1の発現の検討2019
- Author(s)
  石原新、山田裕一、岩崎健、伊東良広、戸田雄、吉本昌人、孝橋賢一、山元英崇、藤原稔史、中島康晴、薛宇孝、遠藤誠、松本嘉寛、中島康晴、小田義直
- Organizer
  日本整形外科学会骨・軟部腫瘍学術総会
- Data Source
  KAKENHI-PROJECT-19H03444
[Presentation] 耳下腺Solitary fibrous tumorの1例2019
- Author(s)
  松下能文, 岩崎健, 山田裕一, 小田義直, 桃崎征也, 久保和彦, 中島寅彦
- Organizer
  日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03444

1. Oda Yoshinao (70291515)

# of Collaborated Projects: 2 results

# of Collaborated Products: 17 results
2. 孝橋賢一 (10529879)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
3. 山元英崇 (30404073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. 山田裕一 (00597643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 松下倫子 (70642198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山村健一郎 (30532858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 田中正剛 (20837265)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坂本一郎 (90616616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 谷口緑 (40965240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 山本猛雄 (50911616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 橋迫美貴子 (70774678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. FUKUSHIMA Mana

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 浅野間和夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 松本嘉寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Iwasaki Takeshi 岩崎 健

Research Projects

Research Products

Co-Researchers

メルケル細胞癌のエピトランスクリプトーム制御の破綻がもたらす腫瘍免疫環境の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

メルケル細胞癌の疲弊T細胞とTLS構成細胞に基づく治療効果予測・耐性機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the Mechanisms and Reversibility of Congestive Hepatic Fibrosis in Right Heart Failure Using Multimodality Approaches

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

空間的マルチオミクス解析による軟部肉腫の腫瘍微小環境の解明と代謝標的治療法の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

シングルセル時空間マルチオミクス解析によるメルケル細胞癌の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epitranscriptomic alteration in soft tissue sarcomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multi-omics analysis of the mechanisms of tumorigenesis and acquired treatment resistance in rare cancer, sarcoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] がんゲノム医療時代の分子腫瘍学 病理と臨床 2022年臨時増刊号（40巻）2022

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Prognostic value of nuclear morphometry in myxoid liposarcoma2023

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Iwasaki Takeshi 岩崎健

[Book] がんゲノム医療時代の分子腫瘍学病理と臨床 2022年臨時増刊号（40巻）2022