Wang Dengli 王登莉

… Alternative Names

WANG Dengli 王登莉

Less

Researcher Number	40815693
Other IDs
Affiliation (Current)	2025: 岡山大学, 医歯薬学域, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 岡山大学, 医歯薬学域, 助教 2019 – 2023: 岡山大学, 医歯薬学総合研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56010:Neurosurgery-related Except Principal Investigator Basic Section 48030:Pharmacology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55030:Cardiovascular surgery-related / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 55040:Respiratory surgery-related / Basic Section 49010:Pathological biochemistry-related
Keywords	Principal Investigator 治療薬 / リボヌクレオタンパク質 / 悪性脳腫瘍 / 炎症 / コラゲナーゼ / マーモセットモデル / HMGB1 / 脳出血 / 抗体治療 Except Principal Investigator HMGB1 … More / HRG / 抗HMGB1抗体 / 虚血再灌流障害 / 血管内皮細胞 / 創薬 / ゼブラフィッシュ / ヘモペキシン / 血漿タンパクとがんの関係 / CRISPR screening / 溶血 / がん / 血漿タンパク / モノクローナル抗体 / HMGB-1 / 脊髄保護 / 脊髄麻痺 / 対麻痺 / 胸部大動脈手術 / 予防法 / 炎症反応 / 脊髄血液関門 / 対麻痺予防 / 大動脈手術 / うさぎ / 脊髄虚血 / 川崎病 / サイトカイン類 / トランスロケーション / 肺移植 / HMGB１ / グリコカリックス / 血管内皮障害 / 細胞死 / 2価鉄イオン / 敗血症 / 高ヒスチジン糖タンパク質 / 胎盤形成 / 妊娠高血圧 / 血圧 / 妊娠 / 高血圧 / 高ヒスチジン血漿タンパク / 胎盤 / 血管リモデリング / 炎症 / トロホブラスト / 妊娠高血圧症候群 / 高ヒスチジン糖タンパク Less

Development of a novel therapeutic drug targeting ribonucleoprotein for glioblastoma modelPrincipal Investigator
- Principal Investigator
  
  王登莉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
Validation and drug development for anti-cancer therapy targeting hemolysis-hemopexin related axis
- Principal Investigator
  
  逢坂大樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Okayama University
Development of new therapeutic drug for Kawasaki disease focusing on HMGB1-HRG balance
- Principal Investigator
  
  Baba Kenji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Okayama University
Verification of preventative effects of monoclonal HMGB1 antibody for spinal cord injury after aortic operation
- Principal Investigator
  
  村岡玄哉
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Kawasaki Medical School
  Okayama University
Elucidation of the vasoprotective mechanism of sepsis-associated DAMPs antagonist HRG
- Principal Investigator
  
  Wake Hidenori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kindai University
Therapeutic effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice
- Principal Investigator
  
  OTANI SHINJI
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  Ehime University
  Okayama University
Application of anti-HMGB1 m Ab in intracerebral hemorrhage-induced brain injury in common marmoset and elucidation of HMGB1 translocation mechanismPrincipal Investigator
- Principal Investigator
  
  WANG Dengli
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Okayama University
Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.
- Principal Investigator
  
  Teshigawara Kiyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Okayama University
Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functions
- Principal Investigator
  
  Nishibori Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Okayama University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy2024
- Author(s)
  Ma Simeng、Nakamura Yoki、Kochi Takahiro、Uemoto Suzuna、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Morioka Norimitsu
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 47 Issue: 1 Pages: 221-226
- DOI
  10.1248/bpb.b23-00729
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2024-01-20
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17930
[Journal Article] Protective effects of an anti-4-HNE monoclonal antibody against liver injury and lethality of endotoxemia in mice2023
- Author(s)
  Qiao Handong、Morioka Yuta、Wang Dengli、Liu Keyue、Gao Shangze、Wake Hidenori、Ousaka Daiki、Teshigawara Kiyoshi、Mori Shuji、Nishibori Masahiro
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 950 Pages: 175702-175702
- DOI
  10.1016/j.ejphar.2023.175702
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17930
[Journal Article] Central high mobility group box-1 induces mechanical hypersensitivity with spinal microglial activation in a mouse model of hemi-Parkinson’s disease2022
- Author(s)
  Sato Fumiaki、Nakamura Yoki、Ma Simeng、Kochi Takahiro、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Morioka Norimitsu
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 145 Pages: 112479-112479
- DOI
  10.1016/j.biopha.2021.112479
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18476, KAKENHI-PROJECT-19H03408
[Journal Article] Role of neuron-derived ATP in paclitaxel-induced HMGB1 release from macrophages and peripheral neuropathy2022
- Author(s)
  Domoto Risa、Sekiguchi Fumiko、Kamaguchi Riki、Iemura Maiko、Yamanishi Hiroki、Tsubota Maho、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 148 Issue: 1 Pages: 156-161
- DOI
  10.1016/j.jphs.2021.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K06608
[Journal Article] Treatment of Marmoset Intracerebral Hemorrhage with Humanized Anti-HMGB1 mAb2022
- Author(s)
  Dengli Wang, Daiki Ousaka, Handong Qiao, Ziyi Wang, Kun Zhao, Shangze Gao, Keyue Liu, Kiyoshi Teshigawara, Kenzo Takada, Masahiro Nishibori
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 19 Pages: 1-22
- DOI
  10.3390/cells11192970
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-22KF0265
[Journal Article] Histamine induced high mobility group box-1 release from vascular endothelial cells through H1 receptor2022
- Author(s)
  Shangze Gao, Keyue Liu, Wenhan Ku, Dengli Wang, Hidenori Wake, Handong Qiao, Kiyoshi Teshigawara, Masahiro Nishibori
- Journal Title
  
  Front Immunol .
  
  Volume: 13 Pages: 1-15
- DOI
  10.3389/fimmu.2022.930683
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17930
[Journal Article] High-mobility group box 1-mediated hippocampal microglial activation induces cognitive impairment in mice with neuropathic pain2022
- Author(s)
  Kazue Hisaoka-Nakashima, Kazuto Ohata, Natsuki Yoshimoto, Shintarou Tokuda, Nanako Yoshii, Yoki Nakamura, Dengli Wang, Keyue Liu, Hidenori Wake, Takayuki Yoshida, Yukio Ago, Kouichi Hashimoto, Masahiro Nishibori, Norimitsu Morioka
- Journal Title
  
  Exp Neurol .
  
  Volume: 355 Pages: 114146-114146
- DOI
  10.1016/j.expneurol.2022.114146
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-20K07291
[Journal Article] Caspase-Dependent HMGB1 Release from Macrophages Participates in Peripheral Neuropathy Caused by Bortezomib, a Proteasome-Inhibiting Chemotherapeutic Agent, in Mice2021
- Author(s)
  Tsubota Maho、Miyazaki Takaya、Ikeda Yuya、Hayashi Yusuke、Aokiba Yui、Tomita Shiori、Sekiguchi Fumiko、Wang Dengli、Nishibori Masahiro、Kawabata Atsufumi
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 10 Pages: 2550-2550
- DOI
  10.3390/cells10102550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K06608
[Journal Article] Perineural high-mobility group box 1 induces mechanical hypersensitivity through activation of spinal microglia: involvement of glutamate-NMDA receptor dependent mechanism in spinal dorsal horn.2021
- Author(s)
  Nakamura Y, Fukuta A, Miyashita K, Zhang FF, Wang D, Liu K, Wake H, Hisaoka-Nakashima K, Nishibori M, Morioka N
- Journal Title
  
  Biochem Pharmacol
  
  Volume: 186 Pages: 114496-114496
- DOI
  10.1016/j.bcp.2021.114496
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07291, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20K18476
[Journal Article] Combinatrial treatment of anti-High Mobility Group Box-1 monoclonal antibody and epothilone B improves functional recovery after spinal cord contusion injury2021
- Author(s)
  Zhu Yicheng、Uezono Naohiro、Yasui Tetsuro、Nakajo Masahide、Nagai Tatsuya、Wang Dengli、Nishibori Masahiro、Nakashima Kinichi
- Journal Title
  
  Neuroscience Research
  
  Volume: 172 Pages: 13-25
- DOI
  10.1016/j.neures.2021.04.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Neuroprotective Effects of Anti-high Mobility Group Box-1 Monoclonal Antibody Against Methamphetamine-Induced Dopaminergic Neurotoxicity2021
- Author(s)
  Masai Kaori、Kuroda Keita、Isooka Nami、Kikuoka Ryo、Murakami Shinki、Kamimai Sunao、Wang Dengli、Liu Keyue、Miyazaki Ikuko、Nishibori Masahiro、Asanuma Masato
- Journal Title
  
  Neurotoxicity Research
  
  Volume: 39 Issue: 5 Pages: 1511-1523
- DOI
  10.1007/s12640-021-00402-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07993, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K07415
[Journal Article] Histidine-Rich Glycoprotein Stimulates Human Neutrophil Phagocytosis and Prolongs Survival through CLEC1A.2021
- Author(s)
  Takahashi Y, Wake H, Sakaguchi M, Yoshii Y, Teshigawara K, Wang D, Nishibori M.
- Journal Title
  
  J Immunol.
  
  Volume: 206(4) Issue: 4 Pages: 737-750
- DOI
  10.4049/jimmunol.2000817
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-16H06277
[Journal Article] Pretreatment with High Mobility Group Box-1 Monoclonal Antibody Prevents the Onset of Trigeminal Neuropathy in Mice with a Distal Infraorbital Nerve Chronic Constriction Injury2021
- Author(s)
  Kochi Takahiro、Nakamura Yoki、Ma Simeng、Hisaoka-Nakashima Kazue、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Irifune Masahiro、Morioka Norimitsu
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 7 Pages: 2035-2035
- DOI
  10.3390/molecules26072035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K18476, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-21K10139
[Journal Article] Histidine-rich glycoprotein possesses antioxidant activity through self-oxidation and inhibition of hydroxyl radical production via chelating divalent metal ions in Fenton's reaction.2020
- Author(s)
  Wake H, Takahashi Y, Yoshii Y, Gao S, Mori S, Wang D, Teshigawara K, Nishibori M.
- Journal Title
  
  Free Radic Res.
  
  Volume: 54(8-9) Issue: 8-9 Pages: 649-661
- DOI
  10.1080/10715762.2020.1825703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] Corticosterone Induces HMGB1 Release in Primary Cultured Rat Cortical Astrocytes: Involvement of Pannexin-1 and P2X7 Receptor-Dependent Mechanisms2020
- Author(s)
  Hisaoka-Nakashima Kazue、Azuma Honami、Ishikawa Fumina、Nakamura Yoki、Wang Dengli、Liu Keyue、Wake Hidenori、Nishibori Masahiro、Nakata Yoshihiro、Morioka Norimitsu
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 5 Pages: 1068-1068
- DOI
  10.3390/cells9051068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408
[Journal Article] High Mobility Group Box-1 and Blood Brain Barrier Disruption2020
- Author(s)
  Nishibori Masahiro、Wang Dengli、Ousaka Daiki、Wake Hidenori
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 12 Pages: 2650-2650
- DOI
  10.3390/cells9122650
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408
[Journal Article] An Evaluation of the Activity of Histidine-Rich Glycoprotein on Differentiated Neutrophil-Like Cells from Human Cell Lines.2020
- Author(s)
  Yoshii Y, Wake H, Nishimura Y, Teshigawara K, Wang D, Nishibori M.
- Journal Title
  
  J Pharmacol Exp Ther.
  
  Volume: 375(3) Issue: 3 Pages: 406-413
- DOI
  10.1124/jpet.120.000182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] Histidine-Rich Glycoprotein Inhibits High-Mobility Group Box-1-Mediated Pathways in Vascular Endothelial Cells through CLEC-1A2020
- Author(s)
  Gao Shangze、Wake Hidenori、Sakaguchi Masakiyo、Wang Dengli、Takahashi Youhei、Teshigawara Kiyoshi、Zhong Hui、Mori Shuji、Liu Keyue、Takahashi Hideo、Nishibori Masahiro
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 6 Pages: 101180-101180
- DOI
  10.1016/j.isci.2020.101180
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17930, KAKENHI-PROJECT-19H03408, KAKENHI-PROJECT-20H03516, KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-16H06277
[Journal Article] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes2020
- Author(s)
  Wang Dengli、Liu Keyue、Fukuyasu Yusuke、Teshigawara Kiyoshi、Fu Li、Wake Hidenori、Ohtsuka Aiji、Nishibori Masahiro
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 3 Pages: 643-643
- DOI
  10.3390/cells9030643
- NAID
  120006860110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07401
[Journal Article] HMGB1 is a therapeutic target and biomarker in diazepam-refractory status epilepticus with wide time window.2019
- Author(s)
  Zhao J, Zheng Y, Liu K, Chen J, Lai N, Fei F, Shi J, Xu C, Wang S, Nishibori M, Wang Y, Chen Z.
- Journal Title
  
  Neurotherapeutics
  
  Volume: in press Issue: 2 Pages: 710-721
- DOI
  10.1007/s13311-019-00815-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Journal Article] Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B2019
- Author(s)
  Nishimura Yoshito、Wake Hidenori、Teshigawara Kiyoshi、Wang Dengli、Sakaguchi Masakiyo、Otsuka Fumio、Nishibori Masahiro
- Journal Title
  
  Pharmacology Research & Perspectives
  
  Volume: 7 Issue: 3
- DOI
  10.1002/prp2.481
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17H03577
[Journal Article] Histidine-rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF-κB and MAPK signal pathway2019
- Author(s)
  Gao S, Wake H, Gao Y, Wang D, Mori S, Liu K, Teshigawara K, Takahashi H, Nishibori M
- Journal Title
  
  Br J Pharmacol.
  
  Volume: 176 Issue: 15 Pages: 2808-2824
- DOI
  10.1111/bph.14711
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06905, KAKENHI-PROJECT-19K07401, KAKENHI-PROJECT-17K15580
[Presentation] 抗HMGB1抗体による脳内出血の治療：霊長類マーモセットを用いた検討2022
- Author(s)
  王登莉、逢坂大樹、喬寒棟、王紫儀、趙坤、勅使川原匡、西堀正洋
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 神経障害性疼痛マウスにおける認知機能傷害に対するHMGB1中和抗体の効果に関する検討2022
- Author(s)
  吉本夏輝、中島一恵、大畑一努、中村庸輝、王登莉、劉克約、和氣秀徳、吾郷由希夫、西堀正洋、森岡徳光
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.2021
- Author(s)
  Kiyoshi Teshigawara, Keyue Liu, Dengli Wang, Hidenori Wake, Shuji Mori, Hideo Kohka Takahashi, Masahiro Nishibori
- Organizer
  The 22nd World Congress of International Society for the Study of Hypertension in Pregnancy (ISSHP2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Treatment of intracerebral hemorrhage with humanized a-HMGB1 mAb in non-human primate brain2021
- Author(s)
  王登莉
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] 抗HMGB1抗体による脳内出血の治療: 霊長類マーモセットを用いた検討2021
- Author(s)
  王登莉
- Organizer
  第36回創薬・薬理フォーラム（岡山）
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] 脊髄虚血再灌流障害に対する抗HMGB-1抗体の有効性の検討2021
- Author(s)
  村岡玄哉、劉克約、喬寒棟、逢坂大樹、王登莉、藤井泰宏、笠原真悟、西堀正洋
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] パーキンソン病における痛覚過敏へのhigh mobility group box-1中和抗体の抑制効果2021
- Author(s)
  佐藤史爽、中村庸輝、麻思萌、河内貴弘、中島一恵、王登莉、劉克約、和氣秀徳、西堀正洋、森岡徳光
- Organizer
  第94回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Anti-high mobility group box-1 (HMGB1) antibody therapy for spinal cord ischemia-reperfusion injury in rabbits2021
- Author(s)
  Genya Muraoka, Keyue Liu, Handong Qiao, Daiki Ousaka, Dengli Wang, Yasuhiro Fujii, Shingo Kasahara, Masahiro Nishibori
- Organizer
  第35回　European Society for Vascular Surgery 総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08823
[Presentation] Treatment of intracerebral hemorrhage with humanized a-HMGB1 mAb in non-human primate brain2021
- Author(s)
  王登莉
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] The therapeutic effects of humanized anti-HMGB1 mAb on intracerebral hemorrhage-induced brain injury in marmoset.2021
- Author(s)
  王登莉
- Organizer
  第44回日本神経科学学会
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] Anti-high mobility group box-1 (HMGB1) antibody therapy for spinal cord ischemia-reperfusion injury in rabbits.2021
- Author(s)
  Muraoka G, Ousaka D, Wang D, Qiao H, Liu K, Nishibori M.
- Organizer
  ESVS 35th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] マウス周産期における血漿高ヒスチジン糖タンパクの生理的動態解析2021
- Author(s)
  勅使川原匡, 劉克約, 王登莉, 和氣秀徳, 森秀治, 高橋英夫, 西堀正洋
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K07290
[Presentation] マウス周産期における血漿高ヒスチジン糖タンパクの生理的動態解析2021
- Author(s)
  勅使川原匡、劉克約、王登莉、和氣秀徳、森秀治、髙橋英夫、西堀正洋
- Organizer
  第94回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 脳出血時のミクログリアにおけるHMGB1トランスロケーションに関する検討2020
- Author(s)
  小橋和馬、長谷川玲央、松川力嗣, 劉克約, 喬寒棟, 和氣秀徳，逢坂大樹，王登莉，西堀正洋
- Organizer
  創薬・薬理フォーラム岡山
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] Histamine induced high mobility group box 1 release from vascular endothelial cells.2020
- Author(s)
  Gao S, Wake H, Liu K, Wang D, Teshigawara K, Nishibori M.
- Organizer
  第22回日本ヒスタミン学会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes2020
- Author(s)
  Dengli Wang, Keyue Liu, Kiyoshi Teshigawara, Hidenori Wake, and Masahiro Nishibori
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] 抗HMGB1抗体による硬膜下血腫の治療2020
- Author(s)
  王登莉、高尚澤、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] The therapeutic effects of anti-HMGB1 mAb on subdural hematoma-induced brain injury in rats2020
- Author(s)
  Dengli Wang, Shangze Gao, Keyue Liu, Hidenori Wake,Kiyoshi Teshigawara, Shuji Mori and Masahiro Nishibori
- Organizer
  第43回日本神経科学学会
- Data Source
  KAKENHI-PROJECT-20K17930
[Presentation] 胎盤形成と妊娠期高血圧における血漿高ヒスチジン糖タンパクの生理的役割の解析2020
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、森秀治、髙橋英夫、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 高ヒスチジン糖タンパク質は敗血症病態下における好中球の状態を制御する2020
- Author(s)
  和氣秀徳、森秀治、高橋英夫、王登莉、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の効果2020
- Author(s)
  吉井将哲、和氣秀徳、勅使川原匡、王登莉、劉克約、髙橋陽平、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 抗HMGB1抗体による硬膜下血腫の治療2020
- Author(s)
  王登莉, 高尚澤, 劉克約, 和氣秀徳, 勅使川原匡, 森秀治, 西堀正洋
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-20K07290
[Presentation] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes.2020
- Author(s)
  王登莉、劉克約、勅使川原匡、和氣秀徳、西堀正洋
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] HRGの作用により球状化した好中球の機能評価2020
- Author(s)
  高橋陽平、和氣秀徳、勅使川原匡、Wang Dengli、吉井将哲、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  日本薬理学会（横浜、新型コロナのため誌上開催、2020年3月16日-18日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] HMGB1 Translocation in Neurons after Ischemic Insult: Subcellular Localization in Mitochondria and Peroxisomes.2020
- Author(s)
  王登莉, 劉克約, 勅使川原匡, 和氣秀徳, 西堀正洋
- Organizer
  第137回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-20K07290
[Presentation] ラットの脳内出血および硬膜下出血に対する抗HMGB1抗体の治療効果2020
- Author(s)
  王登莉、劉克約、和氣秀徳、勅使川原匡、森秀治、西堀正洋
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] 周産期における高ヒスチジン糖タンパク（HRG）の生理的役割の解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019
- Author(s)
  Gao S, Wake H, Sakaguchi M, Wang D, Mori S, Liu K, Teshigawara K, Gao Y, Takahashi H, Nishibori M.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Histidine-rich glycoprotein inhibits high mobility group box 1-mediated pathway in vascular endothelial cells.2019
- Author(s)
  Shangze Gao, Hidenori Wake, Sakaguchi Masakiyo, Dengli Wang, Shuji Mori, Keyue Liu, Kiyoshi Teshigawara, Yuan Gao, Hideo Takahashi, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 好中球様細胞におけるHistidine-Rich Glycoprotein(HRG)の影響2019
- Author(s)
  吉井将哲、和氣秀徳、高橋陽平、王登莉、勅使川原匡、西堀正洋
- Organizer
  日本薬理学会近畿部会（岐阜、2019年6月21日）
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019
- Author(s)
  Wang D, Liu K, Wake H, Teshigawara K, Mori S, Nishibori M.
- Organizer
  9th International DAMPs and Alarmins Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03408
[Presentation] Anti-HMGB1 mAb therapy for intracerebral and subdural hemorrhage in rats.2019
- Author(s)
  Dengli Wang, Keyue Liu, Hidenori Wake, Kiyoshi Teshigawara, Shuji Mori, Masahiro Nishibori.
- Organizer
  9th International DAMPs and Alarmins Symposium (Okayama, JAPAN, Nov 06-08/2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07401
[Presentation] 高ヒスチジン糖タンパク遺伝子欠損マウスにおける妊娠高血圧、及び、胎盤形成異常の解析2019
- Author(s)
  勅使川原匡、劉克約、和氣秀徳、王登莉、髙橋英夫、森秀治、西堀正洋
- Organizer
  日本内分泌学会（仙台、2019年5月9日-11日）
- Data Source
  KAKENHI-PROJECT-19K07401

1. Nishibori Masahiro (50135943)

# of Collaborated Projects: 5 results

# of Collaborated Products: 34 results
2. 逢坂大樹 (70839141)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. Teshigawara Kiyoshi (40403737)

# of Collaborated Projects: 3 results

# of Collaborated Products: 27 results
4. Wake Hidenori (60570520)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
5. 阪口政清 (70379840)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. OTANI SHINJI (10770779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Baba Kenji (40721767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 劉克約 (40432637)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. 山根正修 (20432643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 豊岡伸一 (30397880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 杉本誠一郎 (40570148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡崎幹生 (50467750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 三好健太郎 (50534773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 平井健太 (50814224)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 村岡玄哉 (90816258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 大澤晋 (20643414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 藤井泰宏 (40534673)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 笠原真悟 (90233692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 細野祥之 (60820363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. HISAOKA Kazue

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 中村庸輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
22. 森岡徳光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 浅沼幹人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 宮崎育子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 高橋英夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Wang Dengli 王 登莉

WANG Dengli 王 登莉

Research Projects

Research Products

Co-Researchers

Development of a novel therapeutic drug targeting ribonucleoprotein for glioblastoma modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Validation and drug development for anti-cancer therapy targeting hemolysis-hemopexin related axis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new therapeutic drug for Kawasaki disease focusing on HMGB1-HRG balance

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Verification of preventative effects of monoclonal HMGB1 antibody for spinal cord injury after aortic operation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the vasoprotective mechanism of sepsis-associated DAMPs antagonist HRG

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Therapeutic effects of anti-HMGB1 monoclonal antibody on lung ischemia reperfusion injury in mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Application of anti-HMGB1 m Ab in intracerebral hemorrhage-induced brain injury in common marmoset and elucidation of HMGB1 translocation mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of histidine-rich glycoprotein in prevention of hypertensive disorders of pregnancy and in physiological placental development.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis dynamics of HMGB1 as a biosensor molecule and its multiple functions

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Perineural Treatment with High Mobility Group Box-1 Monoclonal Antibody Prevents Initiation of Pain-Like Behaviors in Female Mice with Trigeminal Neuropathy2024

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Protective effects of an anti-4-HNE monoclonal antibody against liver injury and lethality of endotoxemia in mice2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Central high mobility group box-1 induces mechanical hypersensitivity with spinal microglial activation in a mouse model of hemi-Parkinson’s disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of neuron-derived ATP in paclitaxel-induced HMGB1 release from macrophages and peripheral neuropathy2022

Author(s)

Journal Title

Wang Dengli 王登莉

WANG Dengli 王登莉