Ueno Shin-ichi 上野真一

… Alternative Names

Ueno Shinichi 上野真一

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Researcher Number	40875944
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2023: 順天堂大学, 医学部, 助教 2021: 順天堂大学, 医学部, 特任助教 2020: 順天堂大学, 医学部, 非常勤助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / 0704:Neuroscience, brain sciences, and related fields Except Principal Investigator Basic Section 52020:Neurology-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator バイオマーカー / パーキンソン病 / ダイナミック造影MRI / αシヌクレイン / 進行性核上性麻痺 / 多系統萎縮症 / 血液脳関門 / 伝播 / 血液 / パラビオーシス … More / 伝播凝集 / リポポリサッカライド / 全身臓器 / RT-QuIC / α-シヌクレイン … More Except Principal Investigator α-シヌクレイン / パーキンソン病 / バイオマーカー / 血漿交換療法 / αシヌクレイン / シヌクレイノパチー / IP/RT-QuIC / 多系統萎縮症 / 腸脳連関 / 腸脳関連 / α-シヌクレイン（AS) / 制御性T細胞 / Programmed cell death-1 Less

パーキンソン病病態と血液脳関門の関連の検討Principal Investigator
- Principal Investigator
  
  上野真一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Juntendo University
Elucidation of the Pathology of Synucleinopathies and Development of New Therapies Focused on Serum Alpha-Synuclein Seeds
- Principal Investigator
  
  Taku Hatano
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Juntendo University
Association of blood-derived alpha-synuclein seeds with PD pathologyPrincipal Investigator
- Principal Investigator
  
  Ueno Shinichi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Juntendo University
Pathogenesis role of programmed cell death-1 in Parkinson's disease mouse model
- Principal Investigator
  
  Hattori Nobutaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Juntendo University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Propagative α-synuclein seeds as serum biomarkers for synucleinopathies.2023
- Author(s)
  Ayami Okuzumi Taku Hatano Gen Matsumoto Nobutaka Hattori et al
- Journal Title
  
  Nature medicine
  
  Volume: 29 Issue: 6 Pages: 1448-1455
- DOI
  10.1038/s41591-023-02358-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14785, KAKENHI-PROJECT-21K07283, KAKENHI-PROJECT-21K07424, KAKENHI-PROJECT-21K07444, KAKENHI-PUBLICLY-22H04651, KAKENHI-PROJECT-21H04820, KAKENHI-PROJECT-23K24214
[Journal Article] Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease2021
- Author(s)
  Koinuma Takahiro、Hatano Taku、Kamagata Koji、Andica Christina、Mori Akio、Ogawa Takashi、Takeshige-Amano Haruka、Uchida Wataru、Saiki Shinji、Okuzumi Ayami、Ueno Shin-Ichi、Oji Yutaka、Saito Yuya、Hori Masaaki、Aoki Shigeki、Hattori Nobutaka
- Journal Title
  
  Journal of Parkinson's Disease
  
  Volume: - Issue: 3 Pages: 1-15
- DOI
  10.3233/jpd-202495
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17244, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18H02772, KAKENHI-PROJECT-20F20113, KAKENHI-PROJECT-21K07424
[Journal Article] Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning2021
- Author(s)
  Uehara Yuya、Ueno Shin-Ichi、Amano-Takeshige Haruka、Suzuki Shuji、Imamichi Yoko、Fujimaki Motoki、Ota Noriyasu、Murase Takatoshi、Inoue Takayoshi、Saiki Shinji、Hattori Nobutaka
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 18550-18550
- DOI
  10.1038/s41598-021-98423-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-21H04820
[Journal Article] Ueno SI, Oyama G, Kanai K, Hatano T, Shimo Y, Hattori N. A Retrospective Imaging Evaluation of Presynaptic Dopaminergic Degeneration in Multiple System Atrophy with Levodopa Induced Dyskinesia.2020
- Author(s)
  Ueno SI, Oyama G, Kanai K, Hatano T, Shimo Y, Hattori N
- Journal Title
  
  Tremor Other Hyperkinet Mov (N Y).
  
  Volume: 10 Issue: 0 Pages: 6-6
- DOI
  10.5334/tohm.58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22603
[Journal Article] Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease2020
- Author(s)
  Oji Y, Hatano T, Ueno SI, Funayama M, Ishikawa KI, Okuzumi A, Noda S, Sato S, Satake W, Toda T, Li Y, Hino-Takai T, Kakuta S, Tsunemi T, Yoshino H, Nishioka K, Hattori T, Mizutani Y, Mutoh T, Yokochi F, et al.
- Journal Title
  
  Brain
  
  Volume: 143 Issue: 4 Pages: 1190-1205
- DOI
  10.1093/brain/awaa064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-19K17019, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18K15463, KAKENHI-PROJECT-19K08288, KAKENHI-PROJECT-18K07510, KAKENHI-PROJECT-19K23782
[Journal Article] Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy2019
- Author(s)
  Mori Akio、Ishikawa Kei-Ichi、Saiki Shinji、Hatano Taku、Oji Yutaka、Okuzumi Ayami、Fujimaki Motoki、Koinuma Takahiro、Ueno Shin-Ichi、Imamichi Yoko、Hattori Nobutaka
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 9 Pages: e0223113-e0223113
- DOI
  10.1371/journal.pone.0223113
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18K15376, KAKENHI-PROJECT-19K16928, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15463
[Journal Article] A metabolic profile of polyamines in parkinson disease: A promising biomarker2019
- Author(s)
  Saiki Shinji、Sasazawa Yukiko、Fujimaki Motoki、Kamagata Koji、Kaga Naoko、Taka Hikari、Li Yuanzhe、Souma Sanae、Hatano Taku、Imamichi Yoko、Furuya Norihiko、Mori Akio、Oji Yutaka、Ueno Shin‐Ichi、Nojiri Shuko、Miura Yoshiki、Ueno Takashi、Funayama Manabu、Aoki Shigeki、Hattori Nobutaka
- Journal Title
  
  Annals of Neurology
  
  Volume: 86 Issue: 2 Pages: 251-263
- DOI
  10.1002/ana.25516
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0027, KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18K07829, KAKENHI-PROJECT-19K08003, KAKENHI-PROJECT-19K11752, KAKENHI-PROJECT-19K22603, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-18H02744, KAKENHI-PROJECT-18K15464
[Journal Article] Metabolomics‐based identification of metabolic alterations in PARK22019
- Author(s)
  Okuzumi Ayami、Hatano Taku、Ueno Shin‐Ichi、Ogawa Takashi、Saiki Shinji、Mori Akio、Koinuma Takahiro、Oji Yutaka、Ishikawa Kei‐Ichi、Fujimaki Motoki、Sato Shigeto、Ramamoorthy Sivapriya、Mohney Robert P.、Hattori Nobutaka
- Journal Title
  
  Annals of Clinical and Translational Neurology
  
  Volume: 6 Issue: 3 Pages: 525-536
- DOI
  10.1002/acn3.724
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07797, KAKENHI-PROJECT-18H04043, KAKENHI-PROJECT-16K09675, KAKENHI-PROJECT-19K22603
[Presentation] Analysis of α-synuclein aggregation and proteomics in Parkinson’s disease.2022
- Author(s)
  Ueno SI, Hatano T, Okuzumi A, Oda Y, Hattori N.
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07424
[Presentation] パーキンソン病とPhysical Activity Scale in the Elderlyとの関連についての検討（ポスター）2021
- Author(s)
  若盛亮、王子悠、小川崇、竹重遥香、上野真一、波田野琢、服部信孝
- Organizer
  第62回日本神経学会学術大会、2021年5月20日、国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-19K22603
[Presentation] パーキンソン病・PARK2患者におけるバイオマーカーとしての酸化型アルブミン.2019
- Author(s)
  上野真一, 波田野琢, 奥住文美, 斉木臣二, 王子悠, 森聡生, 濃沼崇博, 藤巻基紀, 安川惠子, 矢冨裕, 池田均, 服部信孝.
- Organizer
  第13回パーキンソン病・運動障害学会コングレス
- Data Source
  KAKENHI-PROJECT-19K22603
[Presentation] Serum non-mercaptalbumin as a potential biomarker in Parkinson’s disease and related disorders2019
- Author(s)
  Ueno SI, Hatano T, Okuzumi A, Saiki S, Oji Y, Mori A, Koinuma T, Fujimaki M, Takeshige-Amano H, Yasukawa K, Yatomi Y, Ikeda H, Hattori N.
- Organizer
  23rd International Congress of Parkinson’s Disease and Movement Disorders. Sep 22-26, Nice, France.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22603

1. Taku Hatano (60338390)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. Hattori Nobutaka (80218510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 佐藤栄人 (00445537)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 森聡生 (60782878)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 奥住文美 (90826075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. FUNAYAMA Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
7. SASAZAWA Yukiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. KAMAGATA KOJI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 斉木臣二

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 石川景一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ueno Shin-ichi 上野 真一

Ueno Shinichi 上野 真一

Research Projects

Research Products

Co-Researchers

パーキンソン病病態と血液脳関門の関連の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the Pathology of Synucleinopathies and Development of New Therapies Focused on Serum Alpha-Synuclein Seeds

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Association of blood-derived alpha-synuclein seeds with PD pathologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis role of programmed cell death-1 in Parkinson's disease mouse model

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Propagative α-synuclein seeds as serum biomarkers for synucleinopathies.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Diffusion MRI Captures White Matter Microstructure Alterations in PRKN Disease2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Non-invasive diagnostic tool for Parkinson’s disease by sebum RNA profile with machine learning2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ueno SI, Oyama G, Kanai K, Hatano T, Shimo Y, Hattori N. A Retrospective Imaging Evaluation of Presynaptic Dopaminergic Degeneration in Multiple System Atrophy with Levodopa Induced Dyskinesia.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variants in saposin D domain of prosaposin gene linked to Parkinson’s disease2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Plasma metabolite biomarkers for multiple system atrophy and progressive supranuclear palsy2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A metabolic profile of polyamines in parkinson disease: A promising biomarker2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolomics‐based identification of metabolic alterations in PARK22019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Analysis of α-synuclein aggregation and proteomics in Parkinson’s disease.2022

Author(s)

Organizer

Data Source

[Presentation] パーキンソン病とPhysical Activity Scale in the Elderlyとの関連についての検討（ポスター）2021

Author(s)

Organizer

Data Source

[Presentation] パーキンソン病・PARK2患者におけるバイオマーカーとしての酸化型アルブミン.2019

Author(s)

Organizer

Ueno Shin-ichi 上野真一

Ueno Shinichi 上野真一