Uehara Yasuaki 上原康昭

Researcher Number	40882907
Other IDs
Affiliation (Current)	2025: 札幌医科大学, 医学部, 訪問研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 札幌医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related Except Principal Investigator Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator オステオポンチン / マクロファージ / RANK / OPG / 破骨細胞 / RANKL / Npt2b / 肺胞微石症 Except Principal Investigator N-glycan / Glycosylation … More / EGFR / 質量分析 / シグナル伝達 / 増殖因子受容体 / ErbB / ErbB4 / 糖鎖 Less

The mechanisms of functional regulation of ErbB4 by N-glycans.
- Principal Investigator
  
  Motoko Takahashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Sapporo Medical University
Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasisPrincipal Investigator
- Principal Investigator
  
  Uehara Yasuaki
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Sapporo Medical University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] N-glycan on N262 of FGFR3 regulates the intracellular localization and phosphorylation of the receptor.2024
- Author(s)
  Hashimoto, U., Fujitani, N., Uehara, Y., Okamoto, H., Saito, A., Ito, F., Ariki, S., Shiratsuchi, A., Hasegawa, Y., Takahashi, M.
- Journal Title
  
  Biochim. Biophys. Acta Gen. Subj.
  
  Volume: 1868 Issue: 4 Pages: 130565-130565
- DOI
  10.1016/j.bbagen.2024.130565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K05698, KAKENHI-PROJECT-21K06083, KAKENHI-PROJECT-21K08207
[Journal Article] Site-specific analysis of N-glycans of receptor tyrosine kinases.2023
- Author(s)
  Takahashi M., Fujitani N., Uehara Y., Hasegawa Y.
- Journal Title
  
  Trends Glycosci. Glycotechnol.
  
  Volume: 35
- Data Source
  KAKENHI-PROJECT-21K06083
[Journal Article] Site-specific analysis of N-glycans of receptor tyrosine kinases2023
- Author(s)
  Takahashi Motoko, Fujitani Naoki, Uehara Yasuaki, Hasegawa Yoshihiro
- Journal Title
  
  Trends in Glycoscience and Glycotechnology
  
  Volume: 35
- Data Source
  KAKENHI-PROJECT-21K06083
[Journal Article] Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis2023
- Author(s)
  Uehara Yasuaki, Tanaka Yusuke, Zhao Shuyang, et al.
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1205-1205
- DOI
  10.1038/s41467-023-36810-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16144, KAKENHI-PROJECT-21K08207
[Journal Article] Site-specific glycosylation analysis of epidermal growth factor receptor 2 (ErbB2): exploring structure and function toward therapeutic targeting2023
- Author(s)
  Fujitani Naoki、Uehara Yasuaki、Ariki Shigeru、Hashimoto Ukichiro、Mukai Jo、Hasegawa Yoshihiro、Takahashi Motoko
- Journal Title
  
  Glycobiology
  
  Volume: 34 Issue: 3 Pages: 130565-130565
- DOI
  10.1093/glycob/cwad100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06083, KAKENHI-PROJECT-21K08207
[Journal Article] N-glycosylation regulates MET processing and signaling2022
- Author(s)
  Atsushi Saitou, Yoshihiro Hasegawa, Naoki Fujitani, Shigeru Ariki, Yasuaki Uehara, Ukichiro Hashimoto, Atsushi Saito, Koji Kuronuma, Kunio Matsumoto, Hirofumi Chiba, Motoko Takahashi
- Journal Title
  
  Cancer Science
  
  Volume: ー Issue: 4 Pages: 1292-1304
- DOI
  10.1111/cas.15278
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17218, KAKENHI-PROJECT-20K22880, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-20K08521, KAKENHI-PROJECT-20K08570, KAKENHI-PROJECT-21K08207, KAKENHI-PROJECT-21K18250, KAKENHI-PROJECT-21K06083
[Journal Article] Integrated Structual Analysis of N-glycans and Free Oligosaccharides Allows for a Quantitative Evalution of ER Stress2021
- Author(s)
  Fujitani N, Ariki S, Hasegawa Y, Uehara Y, Takahashi M.
- Journal Title
  
  Biochemistry
  
  Volume: 60 Issue: 21 Pages: 1708-1721
- DOI
  10.1021/acs.biochem.0c00969
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K22880, KAKENHI-PROJECT-20K08521, KAKENHI-PROJECT-21K06083, KAKENHI-PROJECT-21K08207
[Presentation] 線維芽細胞増殖因子受容体FGFR1の糖鎖の構造と機能2023
- Author(s)
  高橋素子、岡本弘美、藤谷直樹、上原康昭、橋本宇吉郎、長谷川喜弘
- Organizer
  第4２回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21K06083
[Presentation] FGFR1のN型糖鎖はレセプターの細胞内輸送と自己リン酸化を制御する2023
- Author(s)
  岡本弘美、藤谷直樹、上原康昭、長谷川喜弘、橋本宇吉郎、有木茂、白土明子、高橋素子
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06083
[Presentation] ヒトRANKの糖鎖による機能制御メカニズムの解析2022
- Author(s)
  上原康昭, 藤谷直樹, 長谷川喜弘, 有木茂, 橋本宇吉郎, 岡本弘美, 高橋素子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06083
[Presentation] FGFR1の糖鎖の部位特異的構造解析と機能解析2022
- Author(s)
  岡本弘美、藤谷直樹、上原康昭、長谷川喜弘、橋本宇吉郎、有木茂、白土明子、○高橋素子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06083
[Presentation] ヒトErbB2(HER2)の部位特異的糖鎖構造解析2022
- Author(s)
  藤谷直樹, 上原康昭, 長谷川喜弘, 橋本宇吉郎, 有木茂, 高橋素子
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06083
[Presentation] 肝細胞増殖因子受容体METの糖鎖の構造と機能2022
- Author(s)
  高橋素子、齋藤淳、長谷川喜弘、藤谷直樹、有木茂、上原康昭、松本邦夫
- Organizer
  第41回日本糖質学会
- Data Source
  KAKENHI-PROJECT-21K06083
[Presentation] 肺胞微石症における肺破骨細胞様細胞の機能解析2022
- Author(s)
  上原康昭, 長谷川喜弘, 高橋素子, McCormack Francis X.
- Organizer
  第62回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K16144
[Presentation] METの糖鎖による機能制御メカニズムの解析2021
- Author(s)
  齋藤淳、長谷川喜弘、藤谷直樹、有木茂、上原康昭、松本邦夫、高橋素子
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06083

1. Motoko Takahashi (00303941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. 藤谷直樹 (10374191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
3. 長谷川喜弘 (90643180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
4. 齋藤淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 平山明子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Uehara Yasuaki 上原 康昭

Research Projects

Research Products

Co-Researchers

The mechanisms of functional regulation of ErbB4 by N-glycans.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] N-glycan on N262 of FGFR3 regulates the intracellular localization and phosphorylation of the receptor.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Site-specific analysis of N-glycans of receptor tyrosine kinases.2023

Author(s)

Journal Title

Data Source

[Journal Article] Site-specific analysis of N-glycans of receptor tyrosine kinases2023

Author(s)

Journal Title

Data Source

[Journal Article] Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Site-specific glycosylation analysis of epidermal growth factor receptor 2 (ErbB2): exploring structure and function toward therapeutic targeting2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-glycosylation regulates MET processing and signaling2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Integrated Structual Analysis of N-glycans and Free Oligosaccharides Allows for a Quantitative Evalution of ER Stress2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] 線維芽細胞増殖因子受容体FGFR1の糖鎖の構造と機能2023

Author(s)

Organizer

Data Source

[Presentation] FGFR1のN型糖鎖はレセプターの細胞内輸送と自己リン酸化を制御する2023

Author(s)

Organizer

Data Source

[Presentation] ヒトRANKの糖鎖による機能制御メカニズムの解析2022

Author(s)

Organizer

Data Source

[Presentation] FGFR1の糖鎖の部位特異的構造解析と機能解析2022

Author(s)

Organizer

Data Source

[Presentation] ヒトErbB2(HER2)の部位特異的糖鎖構造解析2022

Author(s)

Organizer

Data Source

[Presentation] 肝細胞増殖因子受容体METの糖鎖の構造と機能2022

Author(s)

Organizer

Data Source

[Presentation] 肺胞微石症における肺破骨細胞様細胞の機能解析2022

Author(s)

Organizer

Data Source

[Presentation] METの糖鎖による機能制御メカニズムの解析2021

Author(s)

Organizer

Uehara Yasuaki 上原康昭