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KUO Che-hui  敦 哲輝

ORCIDConnect your ORCID iD *help
… Alternative Names

KUO Cheーhui  郭 哲輝

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Researcher Number 50126570
External Links
Affiliation (based on the past Project Information) *help 2007: 大阪大学, 医学研究科, 准教授
2004: 大阪大学, 大学院・医学研究科, 助教授
2002 – 2004: 大阪大学, 医学系研究科, 助教授
2003: 大阪大学, 大学院・医学研究科情報薬理学, 助教授
2002: 大阪大学, 医学部, 助教授 … More
2000: Graduate School of Medicine Osaka University Associate Professor, 大学院・医学系研究科, 助教授
1999 – 2000: 大阪大学, 医学系研究科, 助教授
1998 – 1999: 大阪大学, 医学部, 助教授
1994 – 1997: 大阪大学, 医学部, 助手
1987 – 1991: 金沢大学, がん研究所, 助手 Less
Review Section/Research Field
Principal Investigator
応用薬理学・医療系薬学 / Neurochemistry/Neuropharmacology / General pharmacology
Except Principal Investigator
General pharmacology / Functional basic dentistry / Functional basic dentistry / 応用薬理学・医療系薬学 / Neurochemistry/Neuropharmacology / General pharmacology / Immunology / Biological Sciences
Keywords
Principal Investigator
Purα / MEKA cDNA / 組織化学 / Calmodulin / 神経 / 複製 / 転写 / Retina / Photoreceptor cell / MEKA protein … More / MEKA蛋白質 / 網膜 / 視細胞 / ホスフォジエステラーゼ / 光受容細胞 / cDNAクローニング / MEKAcDNA / Single stranded DNA (ssDNA) / Nuclear Extract / Brain / Gel shift assay / Overlay assay / PUR element / 構造変化 / ssCRE / 核抽出物 / 一本鎖DNA / 脳 / PURエレメント / オーバーレイアッセイ / Purα結合蛋白(PurBP) / Calcium / Calpain / Transcription / Replication / DNA binding protein / Morphine / CRE / フォルスコリン / 転写神経突起伸展 / 遺伝子発現 / ソマトスタチン / PC12細胞 / カルパイン / カルシウム / カルモデュリン / DNA結合蛋白 / モルヒネ / G protein / Transducin / 分子生物学 / G蛋白質 / G蛋白貭 / トランスデュ-シン / MEKA蛋白貭 … More
Except Principal Investigator
methamphetamine / メタンフェタミン / シナプス / stimulant psychosis / synaptic remodeling / Arcadline / MAP2 / N-cadherin / gene expression Arc / Nitric oxide / Trigeminal nucleus caudalis / Allodynia / NMDA / 下歯槽神経 / 一酸化窒素 / アロディニア / Arc / Amida / 興奮薬精神病 / Purα / gicerin / morphine / モルヒネ / 転写因子 / TNF / Nerve injury / Microdialysis / Peripheral nerve injury / Glutamate / cFos / 疼痛行動 / グルタミン酸受容体 / ニューロパシー / 神経損傷 / 三叉神経脊髄路核 / マイクロダイアリシス / 末梢神経 / グルタミン酸 / cadherin / adhesion / spine / plasticity / synapse / 接着分子 / 可塑性 / カドヘリン / 接着 / スパイン / 可塑性の構造的基盤 / 樹状突起 / 精神依存 / シナプスのリモデリング / Arcadlin / Inferior alveolar nerve / Deafferentation pain / 末梢神経損傷 / 抜髄 / 三叉神経核 / methamphetamine-psychosis / calcium / drug dependence / gene expression / 一本鎖CRE / 依存 / 耐性 / 依存性 / 細胞死 / カルモジュリン / カルシウム / 薬物依存形成 / 遺伝子発現 / reactive astrocytes / cell movement / synaptogenesis / neurite outgrowth factor cell adhesion / 癌化 / 発生 / 腎臓 / 神経察知伸展因子 / 活性ドメイン / ギセリン / シナプス形成 / 細胞接着因子 / イムノグロブリン / gicerin(ギセリン) / 突起伸展因子 / 反応性アストログリア / 神経再生 / 細胞移動 / 神経突起伸展 / 細胞接着 / casein / cAMP response element / DNA-binding protein / puraalpha / ssCRE-BP / dependence / tolerance / 薬物依存 / ISDB法 / DNA結合蛋白 / 小脳 / 大脳 / cDNAクローニング / 一本鎖CRE結合蛋白 / CAMPレスポンスエレメント / purα / cAMPレスポンスエレメント / DNA結合蛋白質 / pur α / カゼイン / 一本鎖CRE結合蛋白質 / 依存耐性 / Transcriptional factors / Interferon gamma / IL-8 gene activation / Signal transduction / Receptor / Interleukin 1 / インタ-ロイキン8遺伝子 / 構造と機能 / シグナル伝達機構 / インタ-ロイキン1受容体 / IL-1シグナル伝達 / IL-6受容体gp130 / インターロイキン8 / インターロイキン1受容体タイプ1 / プロテインキナーゼ / ホルボールエステル / 再潅流障害 / IFNγ / IL-8遺伝子発現 / シグナル伝達 / 受容体 / インターロイキン1 / cGMP / NO合成酵素 / 細胞内カルシウム濃度 / M3ムスカリン受容体 / アクアポリン-8 / アクアポリン-5 / アドレナリン受容体 / 免疫染色 / 導管 / ムスカリン受容体 / 細胞内移動 / 老化 / 糖尿病 / ラフト / 口腔乾燥症 / 唾液腺 / アクアポリン / 水チャネル / 産生不全 / サイトカイン / ヒト単球 / HIV / エイズ Less
  • Research Projects

    (14 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (25 People)
  •  Study on the role of the primary afferent fibers in thedevelopment/maintenance of the intractable pain in the oro-facial region

    • Principal Investigator
      YONEHARA Norifumi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Ohu University
  •  Molecular mechanisms of drug dependency and stimulant psychosis induced by methamphetamine

    • Principal Investigator
      MIKI Naomasa
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Cadherin activity is required for activity-induced spine remodeling.

    • Principal Investigator
      TANAKA Hidekazu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Interaction between Pur α and ssCRE, and Pur α binding proteinsPrincipal Investigator

    • Principal Investigator
      KUO Che-hui
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  アクアポリンと唾液分泌

    • Principal Investigator
      石川 康子, 石田 甫
    • Project Period (FY)
      2001 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Analysis of stimulatory effects of calmodulin on Purα binding to PUR.Principal Investigator

    • Principal Investigator
      KUO Che-hui
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  Alterations of neuronal response and transcription factors in the trigeminal nucleus following deafferentation pain

    • Principal Investigator
      YONEHARA Norifumi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Functional basic dentistry
    • Research Institution
      Osaka University
  •  Transcription factors insolved in the development of drug abuse and therapeutic drugs.

    • Principal Investigator
      MIKI Naomasa
    • Project Period (FY)
      1997 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (A).
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Osaka University
  •  Structures and functions of gicerin, a novel cell adhesion molecule.

    • Principal Investigator
      MIKI Naomasa
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Molecular mechanism and prevention of drug dependence

    • Principal Investigator
      MIKI Naomasa
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Osaka University
  •  HIV感染ヒト単球のサイトカイン産生不全状態の原因解明

    • Principal Investigator
      MATSUSHIMA Kouji
    • Project Period (FY)
      1991
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kanazawa University
  •  Analysis of the structure of interleukin 1 receptor and the mechanism of IL-1 signal transduction

    • Principal Investigator
      MATSUSHIMA Kouji
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Immunology
    • Research Institution
      Kanazawa University
  •  Purification of a Photoreceptor-Specific Meka Protein and its Physiological FunctionPrincipal Investigator

    • Principal Investigator
      KUO Cheーhui
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Kanazawa University
  •  Isolation and characterization of retina specific cDNA clonesPrincipal Investigator

    • Principal Investigator
      KUO Che-Hui
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      応用薬理学・医療系薬学
    • Research Institution
      Cancer Research Institute, Kanazawa University

All 2005 2004 2003

All Journal Article

  • [Journal Article] Concomitant translocation of Purα with Its (PurBPs) from nuclei to cytoplasm during binding proteins neuronal development.2005

    • Author(s)
      L-H.Zen, K.Okamura, H.Tanaka, N.Miki, C-H.Kuo
    • Journal Title

      Neurosci.Res. 51

      Pages: 105-109

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390080
  • [Journal Article] Concomitant translocation of Purα with its binding proteins (PurBPs) from nuclei to cytoplasm during neuronal development.2005

    • Author(s)
      L-H.Zen, K.Okamura, H.Tanaka, N.Miki, C-H.Kuo
    • Journal Title

      Neurosci.Res. 51

      Pages: 105-109

    • NAID

      10015450609

    • Data Source
      KAKENHI-PROJECT-15390080
  • [Journal Article] Characterization of novel Purα-binding proteins in mouse brain.2004

    • Author(s)
      L-H.Zeng, T.Fujimoto, E.Kumamaru, Y.Irie, N.Miki, C-H.Kuo
    • Journal Title

      Neurochem.Int. 45

      Pages: 753-758

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390080
  • [Journal Article] Molecular cloning and characterization of rKAB1, which interacts with KARP-1, localizes in the nucleus and protects cells against oxidative death.2003

    • Author(s)
      E.Do, E.Taira, Y.Irie, Y.Gan, H.Tanaka, C-H.Kuo, N.Miki
    • Journal Title

      Mol.Cell.Biochem. 248

      Pages: 77-83

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390080
  • 1.  MIKI Naomasa (40094445)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 4 results
  • 2.  TAIRA Eiichi (60263240)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  IRIE Yasuyuki (70303948)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 4.  OSUGI Takeshi (50176880)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TANAKA Hidekazu (70273638)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 6.  MATSUSHIMA Kouji (50222427)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  HIGUCHI Hiroshi (30150337)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  YONEHARA Norifumi (70124534)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  TAKEMURA Motohide (70192169)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  石川 康子 (40144985)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  KUNO Kouji (40242565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  AKIYAMA Mariko (60019867)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  YAMAGATA Kanato (20263262)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHINICHI Sugiyo (90397688)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KOIKE Yuuichi (90109421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TAKADA Yoshinobu (40119590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ABE Kenji (60405991)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  石田 甫 (70028364)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  袁 振芳 (80346600)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  飯田 博一 (10335797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  渡辺 康裕 (90127324)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  王 小兵 (30243207)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  古山 昭 (80364454)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  八巻 史子 (60433562)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  YANAGITA Tomoji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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