Oguchi Katsuji 小口勝司

… Alternative Names

OGUCHI Katsuji 小口勝司

OGUCHI Katsuzi 小口勝司

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Researcher Number	50129821
Other IDs
External Links
Affiliation (Current)	2025: 昭和医科大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2016 – 2023: 昭和大学, 医学部, 名誉教授 1998 – 2006: 昭和大学, 医学部, 教授 2000: 昭和大, 医学部, 教授 1992 – 1993: 昭和大学, 医学部, 教授 1988 – 1989: 昭和大学, 医学部, 教授
Review Section/Research Field	Principal Investigator Basic Section 55050:Anesthesiology-related / Applied pharmacology / General pharmacology / 応用薬理学・医療系薬学 Except Principal Investigator General surgery / Conservative dentistry / General pharmacology
Keywords	Principal Investigator リアノジン受容体 / カルシウムイオン / 悪性高熱症 / 遺伝子変異体 / 遺伝子診断 / ryanodine receptor / calcium release channel / calcium ion / CICR / カルシウム放出チャンネル … More / 緑色蛍光蛋白質 / malignant hyperthe / calcium　ion / cDNA cassette / cDNAカセット / malignant hyperthermia / 変異体 / RyR1 / 1型リアノジン受容体 / 薬理学 / 遺伝子 / 細胞内Ca2+イメージング / 培養細胞株 / リアノジン受容体1型 / 遺伝子発現 / 全身麻酔薬 / 疾患モデル / endoplasmic reticulum / green fluorescent protein(GFP) / 部分欠損クローン / 部分領域 / 小胞体 / 緑色蛍光蛋白質(GFP) / malignat hyperthermia / green fluorescent protein / rvanodine receptor … More Except Principal Investigator Tet On-Off / リポソーム / ハイパーサーミア / 強磁性体微粒子 / LYPOSOME / FERROMAGNETIC PARTICLE / HIGH FREQUENCY INDUCTIVE HEATING / HYPERTHERMIA / 腫瘍選択的加温 / リポソ-ム / 高周波誘導加熱 / ハイパ-サ-ミア / Dentin / Discoloration / 原子吸光度 / 象牙質 / 変色 / malignant hyperthermia / ryanodine receptor / calcium release channel / calcium ion / 悪性高熱症 / リアノジン受容体 / カルシウム放出チャンネル / カルシウムイオン / Ferromagnetic particle / Gastrointestial cancer / HIgh frequency inductive heating / Hyperthermia / 高周波誘導加温 / 消化器癌 / 高周波誘導加温法 / 温熱療法 Less

悪性高熱症の遺伝子診断を目指した1型リアノジン受容体遺伝子変異体の作製と発現Principal Investigator
- Principal Investigator
  
  小口勝司
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Showa University
A trial for establishment of the cell banks as the models of malignant hyperthemiaPrincipal Investigator
- Principal Investigator
  
  Oguchi Katsuji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Showa University
SCREENING FOR THE FUNCTIONAL DOMAINS IN THE RYANODINE RECEPTORPrincipal Investigator
- Principal Investigator
  
  OGUCHI Katsuji
- Project Period (FY)
  2003 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  SHOWA UNIVERSITY
Development of the protein caused by discoloration teeth resolution enzyme.
- Principal Investigator
  
  MANABE Atsufumi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Conservative dentistry
- Research Institution
  Showa University
SPATIO-TEMPORAL ANALYSIS OF CA^<2+> RELEASE CHANNEL RELATED TO THE VARIOUS TYPE OF THE INTRACELLULAR CA^<2+> SIGNALSPrincipal Investigator
- Principal Investigator
  
  OGUCHI Katsuji
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  SHOWA UNIVERSITY
THE CONTROL OF CA2+ RELEASE CHANNEL EXPRESSION BY THE TET ON-OFF SYSTEMS.
- Principal Investigator
  
  OYAMADA Hideto
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  SHOWA UNIVERSITY
生きた細胞におけるカルシウム放出チャンネル蛋白質の可視化Principal Investigator
- Principal Investigator
  
  小口勝司
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Showa University
A study of frequency inductive heating using liposomal
- Principal Investigator
  
  ARAI Kazushige
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  SHOWA UNIVERSITY
STUDIES ON LIPOSOMAL FERROMAGNETIC PARTICLES AND A TECHNIQUE OF HIGH FREQUENCY INDUCTIVE HEATING
- Principal Investigator
  
  ARAI Kazushige
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Showa University

All 2022 2020 2019 2017 2004 2003 2002

All Journal Article Presentation

[Journal Article] Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating2022
- Author(s)
  Oyama Kotaro、Zeeb Vadim、Yamazawa Toshiko、Kurebayashi Nagomi、Kobirumaki-Shimozawa Fuyu、Murayama Takashi、Oyamada Hideto、Noguchi Satoru、Inoue Takayoshi、Inoue Yukiko U.、Nishino Ichizo、Harada Yoshie、Fukuda Norio、Ishiwata Shin’ichi、Suzuki Madoka
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 32
- DOI
  10.1073/pnas.2201286119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-21K06789, KAKENHI-PROJECT-22K06652, KAKENHI-PROJECT-21K19929, KAKENHI-PLANNED-20H05785, KAKENHI-PLANNED-22H05053, KAKENHI-PLANNED-22H05054, KAKENHI-PLANNED-22H05055, KAKENHI-PROJECT-20H03421, KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-20K06467, KAKENHI-PROJECT-19H03404, KAKENHI-PROJECT-23K23847, KAKENHI-PROJECT-23K24778, KAKENHI-PROJECT-23K24067
[Journal Article] Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics2020
- Author(s)
  Yamazawa Toshiko、Ogawa Haruo、Murayama Takashi、Yamaguchi Maki、Oyamada Hideto、Suzuki Junji、Kurebayashi Nagomi、Kanemaru Kazunori、Oguchi Katsuji、Sakurai Takashi、Iino Masamitsu
- Journal Title
  
  The Journal of General Physiology
  
  Volume: 152 Issue: 1 Pages: 0-0
- DOI
  10.1085/jgp.201812235
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07105, KAKENHI-PROJECT-19K07306, KAKENHI-PROJECT-19K09383, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-19H03198, KAKENHI-PROJECT-19H03404
[Journal Article] Construction of an all-in-one double-conditional shRNA expression vector2019
- Author(s)
  Kudo Y, Oyamada H, Matsuoka T, Inagaki A, Tsuchiya H, Ao Y, Kimura AM, Tsuji M, Oguchi K, Kiuchi Y.
- Journal Title
  
  Showa Univ J Med Sci
  
  Volume: 31 Pages: 41-50
- NAID
  130007662338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08917
[Journal Article] Effects of troglitazone on diabetic nephropathy and hypercoaglation in KK and KK-A mice fed a high fructose diet2004
- Author(s)
  K Oguchi, et al.
- Journal Title
  
  Showa University Journal of Medical Sciences 16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592030
[Journal Article] Increase in plasma fibrinogen and plasminogen activator inhibitor level in diabetic KK and KK-A mice2003
- Author(s)
  K Oguchi, et al.
- Journal Title
  
  In vivo 17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15592030
[Journal Article] Evaluation of superoxide dismutase activity in dialyzed patients by electron spin response spectroscopy.2002
- Author(s)
  Oguchi et al.
- Journal Title
  
  Am J Nephrol 22
  
  Pages: 16-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15592030
[Presentation] Fast and easy construction method of ryanodine receptor mutants aiming at genetic screening of malignant hyperthermia diagnosis2020
- Author(s)
  Oyamada H, Nakano M, Hayashi T, Ubukata Y, Makino T, Tanaka M, Kikuchi T, Oguchi K, Kiuchi Y.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K09383
[Presentation] Design and constructs of the single “All-in-One”type single double-conditional shRNA expression vectors for a spatio-temporal gene and/or cell targeting2019
- Author(s)
  Oyamada H, Ao Y, Kudo Y, Okamoto R, Matsuoka T, Inagaki A, Aoyama E, Oguchi K, Kiuchi Y.
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K08917
[Presentation] Construction and integration of the All-in-One type single double-conditional shRNA expression vectors for spatio-temporal gene and/or cell targeting.2019
- Author(s)
  Oyamada H, Ao Y, Kudo Y, Matsuoka T, Okamoto R, Murayama T, Yamazawa T, Kakizawa S, Oguchi T, Kimura MA, Yasumoto T, Mori Y, Tsuji M, Oguchi K, Kiuchi Y.
- Organizer
  第42回日本神経科学大会( 共同開催：第62回日本神経化学会大会)
- Data Source
  KAKENHI-PROJECT-19K09383
[Presentation] A novel screeniing method for drugs inhibiting type 1 ryanodine receptor （RyR1) by ER Ca2+ monitoring2017
- Author(s)
  鈴木志奈、秋間龍之介、村山尚、呉林なごみ、湯浅麻里、森修一、影近弘之、鈴木純二、金丸和典、飯野正光、小山田英人、小口勝司、小川治夫、豊島近、櫻井隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08917
[Presentation] Genotype-phenotype correlations of central core disease mutaitions in the C-terminal region fo the RYR1 channel2017
- Author(s)
  村山尚、呉林なごみ、小川治夫、山澤徳志子、小山田英人、小口勝司、櫻井隆
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-16K08917

1. OYAMADA Hideto (50266160)

# of Collaborated Projects: 6 results

# of Collaborated Products: 7 results
2. ARAI Kazushige (50129805)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SUZUKI Satoshi (60216380)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. FUKUSHIMA Motohiko (50238474)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KIUCHI Yuji (50204821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MANABE Atsufumi (40199906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ITOH Kazuo (30129811)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SASA Ryuzi (20014201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MAEDA Masako (00053869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. YOSHIDA Takemi (20138415)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 上地一平

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 村山尚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Oguchi Katsuji 小口 勝司

OGUCHI Katsuji 小口 勝司

OGUCHI Katsuzi 小口 勝司

Research Projects

Research Products

Co-Researchers

悪性高熱症の遺伝子診断を目指した1型リアノジン受容体遺伝子変異体の作製と発現Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A trial for establishment of the cell banks as the models of malignant hyperthemiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SCREENING FOR THE FUNCTIONAL DOMAINS IN THE RYANODINE RECEPTORPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of the protein caused by discoloration teeth resolution enzyme.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

SPATIO-TEMPORAL ANALYSIS OF CA^<2+> RELEASE CHANNEL RELATED TO THE VARIOUS TYPE OF THE INTRACELLULAR CA^<2+> SIGNALSPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

THE CONTROL OF CA2+ RELEASE CHANNEL EXPRESSION BY THE TET ON-OFF SYSTEMS.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生きた細胞におけるカルシウム放出チャンネル蛋白質の可視化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

A study of frequency inductive heating using liposomal

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

STUDIES ON LIPOSOMAL FERROMAGNETIC PARTICLES AND A TECHNIQUE OF HIGH FREQUENCY INDUCTIVE HEATING

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Heat-hypersensitive mutants of ryanodine receptor type 1 revealed by microscopic heating2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insights into channel modulation mechanism of RYR1 mutants using Ca2+ imaging and molecular dynamics2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of an all-in-one double-conditional shRNA expression vector2019

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Effects of troglitazone on diabetic nephropathy and hypercoaglation in KK and KK-A mice fed a high fructose diet2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Increase in plasma fibrinogen and plasminogen activator inhibitor level in diabetic KK and KK-A mice2003

Oguchi Katsuji 小口勝司

OGUCHI Katsuji 小口勝司

OGUCHI Katsuzi 小口勝司