OHNISHI Ken 大西健

Researcher Number	50152195
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2022 – 2023: 茨城県立医療大学, 保健医療学部, 名誉教授 2010 – 2021: 茨城県立医療大学, 保健医療学部, 教授 2012: 茨城県立医療大学, 保険医療学部, 教授 2010: Nara Medical University, 保健医療学部, 教授 2007 – 2009: Nara Medical University School of Medicine, Department of Biology, Associate Professor … More 2004 – 2006: 奈良県立医科大学, 医学部, 助教授 2003: 奈良県立医科大学, 助教授 2000 – 2001: 奈良県立医科大学, 医学部, 助教授 Less
Review Section/Research Field	Principal Investigator Radiation science / Basic Section 52040:Radiological sciences-related / Radiation science Except Principal Investigator Radiation science / Endocrinology / Basic Section 54040:Metabolism and endocrinology-related / Risk sciences of radiation/Chemicals / Biological Sciences
Keywords	Principal Investigator 放射線 / siRNA / p53 / radiation / sensitization / cell survival / DNA-repair / XIAP / NBS1 / apoptosis … More / アポトーシス / 増感剤 / 癌 / 放射線増感 / RNA干渉 / 遺伝子 / CD133 / スフェロイド / がん幹細胞 / cell survival signal transduction / cell death signal transduction / 腫瘍増殖抑制 / 担がんマウス / 分子標的 / 細胞生存シグナル伝達 / 細胞死シグナル伝達 / NF-κB / 癌治療 / 放射線感受性 / DNA修復 / gene transfection / anti-cancer agent / hypothermia / glycerol / molecular chaperone / グリセロール / 遺伝子導入 / 抗癌剤 / 温熱 / グリセオール / 分子シャペロン / 植物生理活性物質 / フラボノイド / フィトケミカル / AKT / シグナル伝達因子 / 増感 … More Except Principal Investigator ステロイドホルモン / 質量分析 / ステロイドホルモン産生 / p53 / アポトーシス / 放射線 / プロテオミクス / コムギ胚芽無細胞タンパク質合成系 / ステロイドホルモン産生組織 / Salt-Inducible Kinases / 標的プロテオミクス / AlphaScreen 法 / 卵巣 / コムギ胚芽無細胞タンパク質合成 / 塩誘導キナーゼ / 副腎 / 質量分析イメージング / 放射線増感 / 副腎皮質 / 脳腫瘍 / がん幹細胞 / 温熱感受性 / ハイパーサーミア / 女性生殖機能 / 質量分析法 / BioID / 近接依存性ビオチン化酵素 / 合成酵素 / イメージング / ステロイド合成酵素 / SIK / 塩誘導性キナーゼ / 排卵 / AlphaScreen / ナノ粒子 / イオン化 / nano-PALDI / MALDI / On Tissue 誘導体化 / 誘導体化試薬 / Nano-PALDI / SALDI / On-Tissue 誘導体化 / molecular targeting / cell survival signal transduction / cell death signal transduction / apoptosis / radiation / 生存シグナル / 細胞死シグナル / 分子標的 / 細胞生存シグナル伝達 / 細胞死シグナル伝達 / 核医学 / グリオーマ細胞株 / フローサイトメトリー / 機能イメージング / 膜蛋白 / 放射性人工アミノ酸 / 薬物動態制御 / アミノ酸トランスポーター / リポソーム / 抗体イメージング / CD133 / 分子イメージング / ＤＮＡ修復 / ヒト腫瘍細胞 / celastrol / がん幹細胞様細胞 / Celastrol / Hsp90阻害剤 / DNA二本鎖切断修復 / セラストロール / ベンチルイソチオシアネート / フィトケミカル / ステロイドホルモン合成酵素 / プロゲステロン / X-zone / 性差 / 内分泌学 / 放射線感受性 / Caspase / Akt-mTOR / Lig4 / アルキル化剤 / X線 / 重粒子線 / DNA修復 / 増感剤 / 感受性 / ヒートショックタンパク質 / コメットアッセイ / アレニウスプロット / 細胞周期 / 温熱抵抗性 / ピストンγH2A / フォーカス形成 / Mre11 / Nbs1 / ヒストンγH2A / DNA二本鎖切断 / 遺伝子導入 / 癌治療 / 抗癌剤 / 温熱 / グリセロール / 分子シャペロン Less

がん幹細胞を標的としたより治療効果の高いホウ素中性子捕捉療法の基礎研究Principal Investigator
- Principal Investigator
  
  大西健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Ibaraki Prefectural University of Health Science
Functional analysis of salt-inducible kinase and steroid-producing tissues by targeted proteomics and mass spectrometry
- Principal Investigator
  
  秦野修
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nara Medical University
Analysis of abnormal steroid hormone production by mass spectrometry imaging and targeted proteomics
- Principal Investigator
  
  Hatano Osamu
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nara Medical University
Establishment of a cancer stem cell line for radiation biological researchPrincipal Investigator
- Principal Investigator
  
  Ohnishi Ken
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Ibaraki Prefectural University of Health Science
Construction of strategy to develop new brain tumor imaging agents targeting cancer stem cells
- Principal Investigator
  
  Shimamoto Naoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Ibaraki Prefectural University of Health Science
Development of direct visualization methods of steroid hormones on tissue sections by imaging mass spectrometry..
- Principal Investigator
  
  Hatano Osamu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Nara Medical University
Radiosensitization of human tumor cells by phytochemicals
- Principal Investigator
  
  NOBUO Kubota
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Ibaraki Prefectural University of Health Science
Screening of radio-sensitizing phytochemicals and examination on their structuresPrincipal Investigator
- Principal Investigator
  
  OHNISHI Ken
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Ibaraki Prefectural University of Health Science
The production mechanism and role of progesterone in female mouse adrenal cortex.
- Principal Investigator
  
  HATANO Osamu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Nara Medical University
Study on the radiation/heat/anti-cancer drag sensitivity enhanced by siRNA in mutated-p53 cancer cellsPrincipal Investigator
- Principal Investigator
  
  OHNISHI Ken
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University
神経がん幹細胞のp53依存的放射線/抗がん剤/温熱感受性の検討
- Principal Investigator
  
  大西武雄
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University
Study on twnor growth inhibition by small interference RNAin nude micePrincipal Investigator
- Principal Investigator
  
  OHNISHI Ken
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University
ヒートショックタンパク質阻害剤による温熱・放射線感受性の増感
- Principal Investigator
  
  大西武雄
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University
Regulation of radiation-induced apoptosis targeting signal transduction factors
- Principal Investigator
  
  OHNISHI Takeo
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Nara Medical University
ハイパーサーミアによるヒストンH2AXのリン酸化機構の解明
- Principal Investigator
  
  高橋昭久
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University
Radiation sensitization of cancer cells by RNA interferencePrincipal Investigator
- Principal Investigator
  
  OHNISHI Ken
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University School of Medicine
分子シャペロンを併用した放射線・温熱癌治療法の基礎的研究
- Principal Investigator
  
  OHNISHI Takeo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Medical University
Fundamental study on molecular chaperone cancer therapyPrincipal Investigator
- Principal Investigator
  
  OHNISHI Ken
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Radiation science
- Research Institution
  Nara Medical University

[Book] 紫外線誘導シグナルトランスダクション.その発現機構とはたらき.In:からだと光の事典2010
- Author(s)
  大西武雄
- Total Pages
  4
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20659194
[Book] からだと光の事典(紫外線誘導シグナルトランスダクション -その発現機構とはたらき-)2010
- Author(s)
  大西武雄
- Publisher
  朝倉書店(in press)
- Data Source
  KAKENHI-PROJECT-20659194
[Book] HSPの発現機構とはたらき.In:からだと光の事典2010
- Author(s)
  大西武雄
- Total Pages
  8
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-20659194
[Book] 理科年表, 国立天文台編纂(宇宙放射線.)2010
- Author(s)
  大西武雄
- Publisher
  丸善(in press)
- Data Source
  KAKENHI-PROJECT-20659194
[Book] からだと光の事典(UV誘導細胞死(アポトーシス))2010
- Author(s)
  大西武雄
- Publisher
  朝倉書店(in press)
- Data Source
  KAKENHI-PROJECT-20659194
[Book] 計る百科(細胞周期, 突然変異, 細胞死を計る)2010
- Author(s)
  大西武雄
- Publisher
  丸善(in press)
- Data Source
  KAKENHI-PROJECT-20659194
[Book] からだと光の事典(Hsp-その発現機構とはたらき)2010
- Author(s)
  大西武雄
- Publisher
  朝倉書店(in press)
- Data Source
  KAKENHI-PROJECT-20659194
[Book] Encyclopedia of Cancer(γH2AX)2009
- Author(s)
  大西武雄
- Total Pages
  3
- Publisher
  Springer-Verlag
- Data Source
  KAKENHI-PROJECT-20659194
[Book] γH2AX In : Encyclopedia of Cancer2009
- Author(s)
  Ohnishi T
- Total Pages
  3
- Publisher
  Springer, Heidelberg
- Data Source
  KAKENHI-PROJECT-20659194
[Book] ハイパーサーミア-がん温熱療法ガイドブック-(分担執筆:温熱による情報伝達の変化)2008
- Author(s)
  大西健
- Publisher
  毎日健康サロン出版(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Book] Encyclopedia of Cancer. (分筆標題:γH2AX)2008
- Author(s)
  Ohnishi T., et. al.
- Publisher
  Springer(in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Book] In:Encyclopedia of Cancer(γH2AX)2008
- Author(s)
  Ohnishi T, et. al.
- Publisher
  Springer(in press)
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 毎日健康サロン、がん温熱療法ガイドブック2008
- Author(s)
  大西健, 分著
- Data Source
  KAKENHI-PROJECT-20591502
[Book] ハイパーザーミア-がん温熱療法ガイドブック-(分担執筆:温熱による情報伝達の変化)2008
- Author(s)
  大西健
- Publisher
  毎日健康サロン出版(印刷中)
- Data Source
  KAKENHI-PROJECT-18591389
[Book] In:ハイパーサーミア-がん温熱療法ガイドブック-(生物学、基礎医学総論-熱と生物)2008
- Author(s)
  大西武雄
- Publisher
  毎日健康サロン出版(in press)
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 理科年表(分筆標題:宇宙放射線)2008
- Author(s)
  大西武雄
- Publisher
  丸善(in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Book] ハイパーサーミア-がん温熱療法ガイドブック-. (分筆標題:生物学、基礎医学総論-熱と生物, pp122-123)2008
- Author(s)
  大西武雄
- Total Pages
  199
- Publisher
  毎日健康サロン出版
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 温熱免疫療法2008
- Author(s)
  大西健
- Publisher
  診断と治療社(印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Book] がんの温熱免疫療法2008
- Author(s)
  大西健, 分著
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-20591502
[Book] 放射線医科学. (分筆標題:光力学治療, レーザー治療, pp115・116)2007
- Author(s)
  大西武雄
- Total Pages
  148
- Publisher
  学会出版センター
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Book] In:放射線医科学.(光力学治療, レーザー治療, pp115-116)2007
- Author(s)
  大西武雄
- Total Pages
  148
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 放射線医科学・監修2007
- Author(s)
  大西武雄監修
- Total Pages
  148
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 放射線医科学・監修2007
- Author(s)
  大西武雄監修
- Total Pages
  148
- Publisher
  学会出版センター
- Data Source
  KAKENHI-PROJECT-17659372
[Book] 計る百科2006
- Author(s)
  大西武雄
- Publisher
  丸善(印刷中)
- Data Source
  KAKENHI-PROJECT-17659372
[Book] Encyclopedia of Cancer(分筆標題 : γH2AX)
- Author(s)
  Ohnishi, T., et. al.
- Publisher
  Springer
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 理科年表(分筆標題 : 宇宙放射線)
- Author(s)
  Ohnishi, T
- Publisher
  丸善
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Book] 温熱免疫療法(分筆標題 : 細胞内の情報伝達に対する温熱の影響)
- Author(s)
  Ohnishi T, et. al.
- Publisher
  診断と治療社
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Book] ハイパーサーミア-がん温熱療法ガイドブック-(分筆標題 : 温熱による情報伝達の変化)
- Author(s)
  Ohnishi, K
- Publisher
  毎日健康サロン出版
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Potentiality of syringetin for preferential radiosensitization to cancer cells.2017
- Author(s)
  Bando-S, Hatano-O, Takemori-H, Kubota-N, Ohnishi-K.
- Journal Title
  
  Int J Radiat Biol.
  
  Volume: 93(3) Issue: 3 Pages: 286-294
- DOI
  10.1080/09553002.2017.1242815
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26670461
[Journal Article] Effectiveness of Hyperthermia on Cancer Stem Cells2017
- Author(s)
  Ken Ohnishi
- Journal Title
  
  Thermal Med.
  
  Volume: 33 Issue: 2 Pages: 29-37
- DOI
  10.3191/thermalmed.33.29
- NAID
  130006140662
- ISSN
  1882-2576, 1882-3750
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10399
[Journal Article] Plastic induction of CD133AC133-positive cells in the microenvironment of glioblastoma spheroid.2014
- Author(s)
  Ohnishi K, Tani T, Bando S, Kubota N, Fujii Y, Hatano O, Harada H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 45 Issue: 2 Pages: 581-586
- DOI
  10.3892/ijo.2014.2483
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293276, KAKENHI-PROJECT-26670461, KAKENHI-PROJECT-26670558, KAKENHI-PROJECT-26670555
[Journal Article] Plastic induction of CD133AC133-positive cells in the microenvironment of glioblastoma spheroid.2014
- Author(s)
  Ohnishi K, Tani T, Bando S, Kubota N, Fujii Y, Hatano O, Harada H
- Journal Title
  
  International Journal of Oncology
  
  Volume: xxx
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] Radiosensitization of human lung cancer cells by the novel purine scaffold Hsp90 inhibitor PI-H712014
- Author(s)
  Segawa T, Fujii Y, Tanaka A, Bando S, Okayasu R, Ohnishi K, Kubota N
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 33 Pages: 559-564
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] 植物由来天然整理活性物質フィトケミカルの放射線増感作用2012
- Author(s)
  板東真一、窪田宜夫、大西健
- Journal Title
  
  放射線生物研究
  
  Volume: 47 Pages: 46-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591845
[Journal Article] 植物由来天然生理活性物質フィトケミカルの放射線増感作用2012
- Author(s)
  坂東真一, 秦野修, 窪田宜夫, 大西健
- Journal Title
  
  放射線生物研究
  
  Volume: 47 Pages: 193-210
- NAID
  40019392914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] 植物由来天然生理活性物質フィトケミカルの放射線増感作用2012
- Author(s)
  坂東真一, 秦野修, 窪田宜夫, 大西健
- Journal Title
  
  放射線生物研究
  
  Volume: 47 Pages: 193-210
- NAID
  40019392914
- Data Source
  KAKENHI-PROJECT-22591015
[Journal Article] Induction of multinucleation in oral squamous cell carcinoma tissue with mutated p53 surviving boron neutron capture therapy.2011
- Author(s)
  Fujita Y, Yamamoto N, Kato I, Iwai S, Ono K, Sakurai Y, Ohnishi K, Ohnishi T, Yura Y
- Journal Title
  
  International Journal of Radiation Biology
  
  Volume: 87 Pages: 293-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] siRNA Targeted for NBS1 enhances heat sensitivity in human anaplastic thyroid carcinoma cells2011
- Author(s)
  Okamoto N, Takahaski A, Ota I, Ohnishi K, Mori E, Kondo N, Noda T, Nakagawa Y, Uemura H, Yane K, Hosoi H, Ohnishi T
- Journal Title
  
  International Journal of Hyperthermia
  
  Volume: 27 Pages: 297-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis.2011
- Author(s)
  Ohara M, Kimura S, Tanaka A, Ohnishi K, Okayasu R, Kubota N
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 28 Pages: 1043-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] Repair pathways independent of the Fanconi anemia nuclear core complex play a predominant role in mitigating formaldehyde-induced DNA damage.2011
- Author(s)
  Noda T, Takahashi A, Kondo N, Mori E, Okamoto N, Nakagawa Y, Ohnishi K, Zdzienicka, MZ, Thompson LH, Helleday T, Asada H, Ohnishi T.
- Journal Title
  
  Biochemical and Biophysical Research Communications 404
  
  Pages: 206-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] Induction of multinucleation in oral squamous cell carcinoma tissue with mutated p53 surviving boron neutron capture therapy.2011
- Author(s)
  Fujita Y, Yamamoto N, Kato I, Iwai S, Ono K, Sakurai Y, Ohnishi K, Ohnishi T, Yura Y.
- Journal Title
  
  International Journal of Radiation Biology. 87
  
  Pages: 293-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] Induction of multinucleation in oral squamous cell carcinoma tissue with mutated p53 surviving boron neutron capture therapy2011
- Author(s)
  Fujita Y, Yamamoto N, Kato I, Iwai S, Ono K, Sakurai Y, Ohnishi K, Ohnishi T, Yura Y
- Journal Title
  
  International Journal of Radiation Biology
  
  Volume: 87 Pages: 293-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis2011
- Author(s)
  Ohara M, Kimura S, Tanaka A, Ohnishi K, Okayasu R. and Kubota N
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 28 Pages: 1043-1047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] siRNA Targeted for NBS1 enhances heat sensitivity in human anaplastic thyroid carcinoma cells.2011
- Author(s)
  Okamoto N, Takahaski A, Ota I, Ohnishi K, Mori E, Kondo N, Noda T, Nakagawa Y, Uemura H, Yane K, Hosoi H, Ohnishi T
- Journal Title
  
  International Journal of Hyperthermia
  
  Volume: 27 Pages: 297-304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] Repair pathways independent of the Fanconi anemia nuclear core complex play a predominant role in mitigating formaldehyde-induced DNA damage2011
- Author(s)
  Noda T, Takahashi A, Kondo N, Mori E, Okamoto N, Nakagawa Y, Ohnishi K, Zdzienicka, MZ, Thompson LH, Helleday T, Asada H, Ohnishi T
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 404 Pages: 206-210
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] Effective new cancer therapies which are independent of p53 gene status.2010
- Author(s)
  Takahashi A, Ohnishi K, Kondo K, Mori E, Noda T, Ohnishi T.
- Journal Title
  
  J Nara Med Assoc 61
  
  Pages: 19-33
- NAID
  120004973499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] 国際宇宙ステーションKibo利用宇宙実験「Rad Gene」の成果報告2010
- Author(s)
  大西武雄
- Journal Title
  
  放射線生物研究
  
  Volume: 45 Pages: 103-126
- NAID
  40017211593
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Signal transduction of radiation and/or hyperthermic cancer therapies2010
- Author(s)
  大西武雄
- Journal Title
  
  Curr Sig Transduct Therapy (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Usefulness of hexamethylenetetramine as an adjuvant to radiation and cisplatin in the treatment of solid tumors : its independency of p53 status.2010
- Author(s)
  Masunaga S, Tano K, Nakamura J, Watanabe M, Kashino G, Takahashi A, Tanaka H, Suzuki M, Ohnishi K, Kinashi Y, Liu Y, Ohnishi T, Ono K.
- Journal Title
  
  J Radiat Res 51
  
  Pages: 27-35
- NAID
  10025914038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] ATM is the predominant kinase involved in the phosphorylation of histone H2AX after heating.2010
- Author(s)
  Takahashi A, Mori E, Su X, Nakagawa Y, Okamoto N, Uemura H, Kondo N, Noda T, Toki A, Ejima Y, Chen JD, Ohnishi K, Ohnishi T.
- Journal Title
  
  J Radiat Res (Tokyo). 51
  
  Pages: 417-422
- NAID
  10026563899
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] p53-Tageted cancer therapies with radiation, hyperthermia and/or anti-cancer agents2010
- Author(s)
  大西武雄
- Journal Title
  
  J Pharmaceuticals (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Biphasic effects of nitric oxide radicals on radiation-induced lethality and chromosome aberrations in human lung cancer cells carrying different p53 gene status.2010
- Author(s)
  Su X, Takahashi A, Guo G, Mori E, Okamoto N, Ohnishi K, Iwasaki T, Ohnishi T.
- Journal Title
  
  Int J Radiat Oncol Biol Phys. 77
  
  Pages: 559-565
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] 国際宇宙ステーション Kibo 利用宇宙実験「Rad Gene」の成果報告2010
- Author(s)
  大西武雄
- Journal Title
  
  放射線生物研究 (in press)
- NAID
  40017211593
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] DNA ligase IV is a potential molecular target in ACNU sensitivity.2010
- Author(s)
  Kondo N, Takahashi A, Mori E, Noda T, Su X, Ohnishi K, McKinnon P, Sakaki T, Nakase H, Ono K, Ohnishi T.
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 1881-1885
- NAID
  10027830813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status.2010
- Author(s)
  Nagata Y, Takahashi A, Ohnishi K, Ota I, Ohnishi T, Tojo T, Taniguchi S.
- Journal Title
  
  International Journal of Oncology. 37
  
  Pages: 1001-1010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] DNA double-strand breaks : their production, recognition, and repair in eukaryotes2009
- Author(s)
  大西武雄
- Journal Title
  
  Mutat Res 669
  
  Pages: 8-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] DNA ligase IV as a new molecular target for temozolomide2009
- Author(s)
  Kondo N, Takahashi A, Mori E, Ohnishi K, McKinnon PJ, Sakaki T, Nakase H, Ohnishi T
- Journal Title
  
  Biochem Biophys Res Commun 387
  
  Pages: 656-660
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] ほ乳動物培養細胞における宇宙環境曝露後のp53調節遺伝子群の遺伝子発現.2009
- Author(s)
  大西武雄
- Journal Title
  
  マイクログラビティ (in press)
- NAID
  10024594986
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Expression of p53-regulated genes in cultured mammalian cells after exposure to a space environment2009
- Author(s)
  大西武雄
- Journal Title
  
  Biol Sci Space 23
  
  Pages: 3-10
- NAID
  10025115182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Role of p53 mutation in the effect of boron neutron capture therapy on oral squamous cell carcinoma.2009
- Author(s)
  Fujita Y, Kato I, Iwai S, Ono K, Suzuki M, Sakurai Y, Ohnishi K, Ohnishi T, Yura Y
- Journal Title
  
  Radiat Oncol電子ジャーナル 4,No.63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] Detection of space radiation-induced double strand breaks as a track in cell nucleus2009
- Author(s)
  大西武雄
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 485-488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] p53 targeting can enhance cancer therapy via radiation,heat and anti-cancer agents2008
- Author(s)
  Ohnishi T, et. al.
- Journal Title
  
  Anticancer Agents Med Chem (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP2008
- Author(s)
  Ohnishi K, Nagata Y, Takahashi A, Taniguchi S, Ohnishi T
- Journal Title
  
  Oncol Rep 20
  
  Pages: 57-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targetin XIAP.2008
- Author(s)
  Ohnishi K, et. al.
- Journal Title
  
  Oncol Rep. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP2008
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Oncology Reports (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP2008
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  Oncology Reports (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Heat induces H2AX foci formation in mammalian cells2008
- Author(s)
  Takahashi A, Mori E, Somakos GI, Ohnishi K, Ohnishi T
- Journal Title
  
  Mutat Res/Genet Toxicol and Environ Mutagen 656
  
  Pages: 88-92
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents.2008
- Author(s)
  Ohnishi T, et. al.
- Journal Title
  
  Anticancer Agents Med Chem. (in press)
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] 放射線適応応答のしくみの再考.2008
- Author(s)
  大西武雄
- Journal Title
  
  放射線生物研究 43
  
  Pages: 91-99
- NAID
  40015940993
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Time course and spacial distribution of UV effects on human skin in organ culture2008
- Author(s)
  Mori E, Takahashi A, Kitagawa K, Kakei S, Tsujinaka D, Unno M, Nishikawa S, Ohnishi K, Hatoko M, Murata N, Watanabe M, Furusawa Y, Ohnishi T
- Journal Title
  
  J Radiat Res 49
  
  Pages: 269-277
- NAID
  110006666025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] 放射線適応応答のしくみの再考.2008
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  放射線生物科学 43
  
  Pages: 91-99
- NAID
  40015940993
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents2008
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  Anticancer Agents in Medicinal Chemistry (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] DNA damage recognition proteins localize along heavy ion induced tracks in the cell nucleus2008
- Author(s)
  Takahashi A, Yamakawa N, Kirita T, Omori K, Ishioka N, Furusawa Y, Mori E, Ohnishi K, Ohnishi T
- Journal Title
  
  J Radiat Res 49
  
  Pages: 645-652
- NAID
  110006985824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] 放射線適応応答のしくみの再考2008
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  放射線生物研究 43
  
  Pages: 91-99
- NAID
  40015940993
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents2008
- Author(s)
  Ohnishi T, Takahashi A, Mori E, Ohnishi K
- Journal Title
  
  Anticancer Agents Med Chem 8
  
  Pages: 564-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP2008
- Author(s)
  Ohnishi K
- Journal Title
  
  Oncol Rep 20
  
  Pages: 57-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP.2008
- Author(s)
  Ohnishi K.
- Journal Title
  
  Oncol Rep. 20
  
  Pages: 57-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents.2008
- Author(s)
  Ohnishi T
- Journal Title
  
  Anticancer Agents Med Chem 8
  
  Pages: 564-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Protein microarray analysis of apoptosis-related protein expression following heat shock in human tongue squamous cell carcinomas containing different p53 phenotypes2008
- Author(s)
  Kajihara A, Takahashi A, Ohnishi K, Imai Y, Yamakawa N, Yasumoto J, Ohnishi T, Kirita T
- Journal Title
  
  Int J Hyperthermia 24
  
  Pages: 605-612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] 放射線・紫外線・温熱の認識・受容・応答・適応-その分子機構-.2008
- Author(s)
  大西武雄
- Journal Title
  
  月刊「自然食ニュース」 419
  
  Pages: 424-435
- Data Source
  KAKENHI-PROJECT-20659194
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targeting XIAP.2008
- Author(s)
  Ohnishi K, et. al.
- Journal Title
  
  Oncol Rep. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA targetingXIAP2008
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Oncology Reports (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation2008
- Author(s)
  Yamakawa N, Takahashi A, Mori E, Imai Y, Furusawa Y, Ohnishi K, Kirita T, Ohnishi T
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1455-1460
- NAID
  10024008916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] p53 targeting can enhance cancer therapy via radiation,heat and anti-cancer agents.2008
- Author(s)
  Ohnishi T, et. al.
- Journal Title
  
  Anticancer Agents Med Chem. (in press)
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] p53 targeting can enhance cancer therapy via radiation. heat and anti-cancer agents2008
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  Anticancer Agents in Medicinal Chemistry 8
  
  Pages: 563-570
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Development of thermotolerance requires interaction between polymerase-beta and heat shock proteins2008
- Author(s)
  Takahashi A, Yamakawa N, Mori E, Ohnishi K, Yokota S, Sugo N, Aratani Y, Koyama H, Ohnishi T
- Journal Title
  
  Cancer Sci 99
  
  Pages: 973-978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents.2008
- Author(s)
  Ohnishi T.
- Journal Title
  
  Anticancer Agents Med Chem. 8
  
  Pages: 564-570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Journal Article] p53 targeting can enhance cancer therapy via radiation, heat and anti-cancer agents2008
- Author(s)
  Ohnishi T., et. al.
- Journal Title
  
  Anticancer Agents in Medicinal Chemistry 8
  
  Pages: 563-570
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 放射線適応応答のしくみの再考2008
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  放射線生物研究 43
  
  Pages: 91-99
- NAID
  40015940993
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Effective enhancement of X-ray-induced apoptosis in human cancer cells with mutated p53 by siRNA tareetina XIAP2008
- Author(s)
  Ohnishi K, et. al.
- Journal Title
  
  Oncology Reports (in press)
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] ハイパーサーミア-がん温熱療法ガイドブック-,(分筆標題 : 生物学、基礎医学総論-熱と生物)2008
- Author(s)
  Ohnishi, T
- Journal Title
  
  毎日健康サロン出版
  
  Pages: 122-123
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 注目されるハイパーサーミアがん治療-そのしくみを科学する.2007
- Author(s)
  大西武雄
- Journal Title
  
  補完代替医療学会誌 4
  
  Pages: 1-7
- NAID
  130000079386
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] ハイパーサーミア治療-その分子機構-2007
- Author(s)
  Ohnishi, T
- Journal Title
  
  治療 ; 相補・代替医療の現況をみる 89
  
  Pages: 1323-1329
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 宇宙実験から知りえたもの-宇宙空間で発酵を考える2007
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  温故知新 44
  
  Pages: 43-53
- NAID
  40015599341
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 注目されるハイパーサーミアがん治療-そのしくみを科学する2007
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  補完代替医療学会誌 4
  
  Pages: 1-7
- NAID
  130000079386
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 注目されるハイパーサーミアがん治療-そのしくみを科学する2007
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  補完代替医療学会誌 4
  
  Pages: 1-7
- NAID
  130000079386
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 放射線生物研究の面白さ、研究者を増やす対策2007
- Author(s)
  大西武雄
- Journal Title
  
  日本放射線腫瘍学会NEWSLETTER 86
  
  Pages: 17-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 注目されるハイパーサーミアがん治療-そのしくみを科学する2007
- Author(s)
  大西武雄ら
- Journal Title
  
  補完代替医療学会誌 4巻
  
  Pages: 1-7
- NAID
  130000079386
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] Hyperthermic sensitizers targeting heat-induced signal transductions.2007
- Author(s)
  Ohnishi K, et. al.
- Journal Title
  
  Ann Cancer Res Ther. 15
  
  Pages: 35-40
- NAID
  130000119679
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Hyperthermic sensitizers targeting heat-induced signal transductions2007
- Author(s)
  Ohnishi K, et. al.
- Journal Title
  
  Annals Cancer Research Therapy 15
  
  Pages: 35-40
- NAID
  130000119679
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] ハイパーサーミア治療-その分子機構-.2007
- Author(s)
  大西武雄
- Journal Title
  
  治療, 相補・代替医療の現況をみる 89
  
  Pages: 1323-1329
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] ハイパーサーミア治療-その分子機構2007
- Author(s)
  大西武雄
- Journal Title
  
  治療, 相補、代替医療の現況をみる 89
  
  Pages: 1323-1329
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 宇宙を利用するライフサイエンスー宇宙へヒトが活躍する場の拡大に向けて.2007
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  Isotope News 633
  
  Pages: 2-12
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 放射線生物研究の面白さ・研究者を増やす対策.2007
- Author(s)
  大西武雄
- Journal Title
  
  日本放射線腫瘍学会NEWSLETTER 86
  
  Pages: 17-19
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Hyperthermic sensitizers targeting heat-induced signal transductions2007
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  Annals Cancer Research Therapy 15
  
  Pages: 35-40
- NAID
  130000119679
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 放射線医科学.(分筆標題 : 光力学治療, レーザー治療)2007
- Author(s)
  Ohnishi, T
- Journal Title
  
  学会出版センター
  
  Pages: 115-116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Hyperthermic sensitizers targeting heat-induced signal transductions2007
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Annals Cancer Research Therapy 15
  
  Pages: 35-40
- NAID
  130000119679
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 放射線生物研究の面白さ・研究者を増やす対策2007
- Author(s)
  Ohnishi, T
- Journal Title
  
  日本放射線腫瘍学会NEWSLETTER 86
  
  Pages: 17-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 宇宙実験から知りえたもの-宇宙空間で発酵を考える2007
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  温故知新 44
  
  Pages: 43-53
- NAID
  40015599341
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 注目されるハイパーサーミアがん治療-そのしくみを科学する2007
- Author(s)
  大西武雄ら
- Journal Title
  
  補完代替医療学会誌 4巻
  
  Pages: 1-7
- NAID
  130000079386
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Hyperthermic sensitizers targeting heat-induced signal transductions2007
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Annals Cancer Research Therapy 15
  
  Pages: 35-40
- NAID
  130000119679
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] 宇宙実験から知りえたもの-宇宙空間で発酵を考える.2007
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  温故知新 44
  
  Pages: 43-53
- NAID
  40015599341
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Induction of radiation resistance by a heat shock protein inhibitor,KNK437,in human glelioblastoma cells2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  International Journal of Radiation Biology 82
  
  Pages: 569-575
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Heat-induced phospkorylation of NBS1 in human skin cells2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Journal of Cellular Biochemistry 99
  
  Pages: 1642-1650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Induction of radiation, resistance by a heat shock protein inhibitor, . KNK437, in human glioblastoma cells2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  International Journal of Radiation Biology 82
  
  Pages: 569-575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Ly294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Int. J. Radiat. Biol. 82巻
  
  Pages: 569-575
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] LY294002, an inhibitor of PI-3K, enhances heat sensitivity indepenendently of P53 status in human lung cancer cells2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  International Journal of Oncology 29
  
  Pages: 249-253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  J. Cell. Biochem. 99巻
  
  Pages: 1642-1650
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] 放射線適応応答のしくみを探る2006
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  月刊エネルギー, 特集号
  
  Pages: 8-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Induction of radiation resistance by a heat shock protein inhibitor,KNK437,in human glioblastoma cells2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  International Journal of Radiation Biology 82
  
  Pages: 569-575
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] ハイパーサーミア療法特集2006
- Author(s)
  Ohnishi, T
- Journal Title
  
  週刊朝日6月16日号
  
  Pages: 73-75
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] LY294002,an inhibitor of PI-3K,enhances heat sensitivity independently of p53 status in human lung cancer cells2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  International Journal of Oncology 29
  
  Pages: 249-253
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Radiat. Res. 166巻
  
  Pages: 454-462
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] LY294002, an inhubitor of PI-3K, enhances heat sensitivity independently of p53 atatus in human lung cancer cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Int. J. Oncol. 29巻
  
  Pages: 249-253
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシャペロン分子2006
- Author(s)
  大西健, et. al.
- Journal Title
  
  放射線生物研究 41
  
  Pages: 99-108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] 変異型p53タンパク質に正常綿を回復陣るシャペロン分子2006
- Author(s)
  大西健, et. al.
- Journal Title
  
  放射線生物研究 41
  
  Pages: 99-108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Int. J. Radiat. Biol. 82巻
  
  Pages: 569-575
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] siRNA targeting NBSI or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  Radiation Research 166
  
  Pages: 454-462
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] LY294002,an inhibitor of PI-3K,enhances heat sensitivity independently ofp53 status in human lung cancer cells2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  International Journal of Oncology 29
  
  Pages: 249-253
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  Journal of Cellular Biochemistry 99
  
  Pages: 1642-1650
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 極限の生物2006
- Author(s)
  Ohnishi, T., et. al.
- Journal Title
  
  科学 76
  
  Pages: 824-826
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] An inhibitor of PI-3K, LY294002, enhances heat sensitivity of human lung cancer cells p53-independently2006
- Author(s)
  Ohnishi, K. et al.
- Journal Title
  
  International Journal of Oncology (in press)
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Radiat. Res. 166巻
  
  Pages: 454-462
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells.2006
- Author(s)
  Ohnishi K., et al.
- Journal Title
  
  Int.J.Oncol. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  癌の臨床 52
  
  Pages: 41-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  Journal of Cellular Biochemistry 99
  
  Pages: 1642-1650
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] DNA修復関連遺伝子を標的症としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  Ohnishi, X., et. al.
- Journal Title
  
  癌の臨床 52
  
  Pages: 41-45
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  大西健ら
- Journal Title
  
  癌の臨床 52巻
  
  Pages: 41-45
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  International Journal of Oncology 29
  
  Pages: 249-253
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシャペロン分子2006
- Author(s)
  大西健ら
- Journal Title
  
  放射線生物研究 41巻
  
  Pages: 99-108
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  大西健, et. al.
- Journal Title
  
  癌の臨床 52
  
  Pages: 41-45
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  J. Cell. Biochem. 99巻
  
  Pages: 1642-1650
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells.2006
- Author(s)
  Ohnishi K., Yasumoto J.-I., Takahashi A., Ohnishi T.
- Journal Title
  
  Int.J.Oncol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] siRNA targeting NBSI or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Radiation Research 166
  
  Pages: 454-462
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells.2006
- Author(s)
  Ohnishi K., et al.
- Journal Title
  
  J.Cell.Biochem. (in press)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] siRNA targeting NBSJ or MIAP increases radiation sensitivity of human cancer cells independent of TP53 status2006
- Author(s)
  Ohnishi K., et. al.
- Journal Title
  
  Radiation Research 166
  
  Pages: 454-462
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] An inhibitor of PI-3K, LY294002, enhances heat sensitivity of human lung cancer cells p53-mdependently2006
- Author(s)
  Ohnishi, K. et al.
- Journal Title
  
  International Journal of Oncology (in press)
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] LY294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Int. J. Oncol. 29巻
  
  Pages: 249-253
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシャペロン分子2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  放射線生物研究 41
  
  Pages: 99-108
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells2006
- Author(s)
  Ohnishi, K. et al.
- Journal Title
  
  Journal of Cellular Biochemistry (in press)
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] ハイパーサーミア療法特集2006
- Author(s)
  大西武雄
- Journal Title
  
  週刊朝日 6月16日号
  
  Pages: 73-75
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Induction of radiation resistance by a heat shock protein inhibitor, KNK437, in human glioblastoma cells2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Intemational Journal of Radiation Biology 82
  
  Pages: 569-575
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells2006
- Author(s)
  Ohnishi, K., et. al.
- Journal Title
  
  Journal of Cellular Biochemistry 99
  
  Pages: 1642-1650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシャペロン分子2006
- Author(s)
  大西健他
- Journal Title
  
  放射線生物研究 41
  
  Pages: 99-108
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] 放射線適応応答のしくみを探る2006
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  月刊エネルギー特集号
  
  Pages: 8-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシャペロン分子2006
- Author(s)
  大西健ら
- Journal Title
  
  放射線生物研究 41巻
  
  Pages: 99-108
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  大西健ら
- Journal Title
  
  癌の臨床 52巻
  
  Pages: 41-45
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシャペロン分子2006
- Author(s)
  大西健ら
- Journal Title
  
  放射線生物研究 41巻
  
  Pages: 99-108
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] Ly294002, an inhibitor of PI-3K, enhances heat sensitivity independently of p53 status in human lung cancer cells.2006
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Int. J. Oncol. 29巻
  
  Pages: 249-253
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  大西健, et. al.
- Journal Title
  
  癌の臨床 52
  
  Pages: 41-45
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2006
- Author(s)
  大西健ら
- Journal Title
  
  癌の臨床 52巻
  
  Pages: 41-45
- Data Source
  KAKENHI-PROJECT-17659372
[Journal Article] 極限の生物2006
- Author(s)
  大西武雄, et. al.
- Journal Title
  
  科学 76
  
  Pages: 824-826
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] The role of the p53 molecule in cancer therapies.2005
- Author(s)
  Ohnishi, T.
- Journal Title
  
  Journal Cancer Research Therapy (印刷中)
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2005
- Author(s)
  大西健他
- Journal Title
  
  癌の臨床 (印刷中)
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] The role of the p53 molecule in cancer therapies with radiation and/or hvnerthermia2005
- Author(s)
  Ohnishi T.
- Journal Title
  
  Journal Cancer Research Therapy 1
  
  Pages: 147-150
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] The role of the p53 molecule in cancer therapies with radiation and/or2005
- Author(s)
  Ohnishi, T
- Journal Title
  
  hyperthennia Journal Cancer Research Therapy 1
  
  Pages: 147-150
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] Apoptosis induced by high-LET radiations is not affected by cellular p53 gene status.2005
- Author(s)
  Takahashi A., Matsumoto H., Furusawa Y., Ohnishi K., Ishioka N., Ohnishi T.
- Journal Title
  
  International Journal of Radiation Biology 81
  
  Pages: 581-586
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] The role of the p53 molecule in cancer therapies.2005
- Author(s)
  Ohnishi, T.
- Journal Title
  
  Journal Cancer Research Therapy (印刷中)
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Glycerol enhances radiosensitivity in a human oral squamous cell carcinoma cell line (Ca9-22) bearing a mutant p53 gene via Bax-mediated induction of apoptosis.2005
- Author(s)
  Imai Y., Ohnishi K., Yasumoto J.-I., Kajiwara A., Yamakawa N., Takahashi A., Ohnishi T., Kirita T.
- Journal Title
  
  Oral Oncology 41
  
  Pages: 631-636
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Combination of the antivascular agent ZD6126 with hypoxic cytotoxin treatment, with reference to the effect on quiescent tumor cells and the dependency on p53 status of rumor cells.2005
- Author(s)
  Masunaga S., Nagasawa H., Uto Y., Hori H., Ohnishi K., Takahashi A., Ohnishi T., Suzuki M., Nagata K., Kinashi Y., Ono K.
- Journal Title
  
  Oncology Reports 14
  
  Pages: 393-400
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感2005
- Author(s)
  大西健他
- Journal Title
  
  痛の臨床 (印刷中)
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] 変異型p53タンパク質に正常機能を回復させるシヤペロン分子2005
- Author(s)
  大西健他
- Journal Title
  
  放射線生物研究 41
  
  Pages: 99-108
- Data Source
  KAKENHI-PROJECT-17201015
[Journal Article] C-terminal peptides of p53 molecules enhance radiation-induced apoptosis in human mutant p53 cancer cells.2004
- Author(s)
  Ohnishi K.et al.
- Journal Title
  
  Apoptosis 9
  
  Pages: 591-597
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.2004
- Author(s)
  Ohnishi K., et al.
- Journal Title
  
  Int.J.Radiat.Biol. 80
  
  Pages: 607-614
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Radiation-induced apoptosis in SCID mouse spleen after low dose or low dose-rate irradiation.2004
- Author(s)
  Takahashi A., Ohnishi K., Ohnishi T.
- Journal Title
  
  International Journal of Low Radiation 1
  
  Pages: 199-207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] C-terminal peptides of p53 molecules enhance radiation-induced apoptosis in human mutant p53 cancer cells.2004
- Author(s)
  Ohnishi K., Takahashi A., Inaba H., Yasumoto J., Yuki K., Ohnishi T.
- Journal Title
  
  Apotosis 9
  
  Pages: 591-597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status alone.2004
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  International Journal of Radiation Biology 80
  
  Pages: 607-614
- Data Source
  KAKENHI-PROJECT-12217130
[Journal Article] 免疫力の活性化も期待できるガン細胞を熱攻めする治療法2004
- Author(s)
  大西武雄
- Journal Title
  
  Natural Medicine 4
  
  Pages: 1-11
- Data Source
  KAKENHI-PROJECT-12217130
[Journal Article] High-LET radiation enhanced apoptosis but not necrosis regardless of p53 status2004
- Author(s)
  Takahashi A, Matsumoto H, Yuki K, Yasumoto J, Kajihara A, Aoki M, Furusawa Y, Ohnishi K, Ohnishi T.
- Journal Title
  
  International Journal of Radiation Oncology Biology Physics 60
  
  Pages: 591-597
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status alone2004
- Author(s)
  Ohnishi K, et al.
- Journal Title
  
  Int J Radiat Biol 80
  
  Pages: 607-614
- Data Source
  KAKENHI-PROJECT-16659324
[Journal Article] Glycerol enhances CDDP-induced growth inhibition of thyroid anaplastic carcinoma tumor carrying mp53 gene.2004
- Author(s)
  Yuki K., Takahashi A., Ota I., Ohnishi K., Yasumoto J.-i, Kanata H., Yane K., Hosoi H., Ohnishi T.
- Journal Title
  
  Oncology Reports 11
  
  Pages: 821-824
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.2004
- Author(s)
  Ohnishi K., Takahashi A., Yokota S., Ohnishi T.
- Journal Title
  
  International Journal of Radiation Biology 80
  
  Pages: 607-614
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] C-terminal peptides of p53 molecules enhance radiation-induced apoptosis in human mutant p53 cancer cells.2004
- Author(s)
  Ohnishi K., et al.
- Journal Title
  
  Apotosis 9
  
  Pages: 597-597
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] C-terminal peptides of p53 molecules enhance radiation-induced apoptosis in human mutant p53 cancer cells.2004
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Apoptosis 9
  
  Pages: 591-597
- Data Source
  KAKENHI-PROJECT-12217130
[Journal Article] Evidence for the involvement of double-stand breaks in heat-induced cell killing.2004
- Author(s)
  Takahashi A., Matsumoto H., Nagayama K., Kitano M., Hirose S., Tanaka H., Mori E., Yamakawa N., Yasumoto J., Yuki K., Ohnishi K., Ohnishi T.
- Journal Title
  
  Cancer Research 64
  
  Pages: 8839-8845
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status alone.2004
- Author(s)
  Ohnishi K.et al.
- Journal Title
  
  International Journal of Radiation Biology 80
  
  Pages: 607-614
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Hyperthermic cancer therapy combined with inhibitors targeted against heat-induced signaling factors.2004
- Author(s)
  Ohnishi K.et al.
- Journal Title
  
  Japanese Journal of Hyperthermic Oncology 20
  
  Pages: 143-159
- NAID
  10029675920
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Hyperthermic cancer therapy combined with inhibitors targeted against heat-induced signaling factors.2004
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Japanese Journal of Hyperthermic Oncology 20
  
  Pages: 143-159
- NAID
  10029675920
- Data Source
  KAKENHI-PROJECT-12217130
[Journal Article] Apoptosis-related gene expression after hyperthermia in human tongue squamous cell carcinoma cells harboring wild-type or mutated p53.2004
- Author(s)
  Yasumoto J., Kirita T., Takahashi A., Ohnishi K., Imai Y., Yuki K., Ohnishi T.
- Journal Title
  
  Cancer Letter 204
  
  Pages: 41-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Sensitization by glycerol for CDDP-therapy against human cultured cancer cells and tumors bearing mutated p53 gene.2004
- Author(s)
  Yuki K., Takahashi A., Ota I., Ohnishi K., Yasumoto J., Yane K., Kanata H., Hosoi H., Ohnishi T.
- Journal Title
  
  Apotosis 9
  
  Pages: 853-859
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Hyperthermic cancer therapy combined with inhibitors targeted against heat-induced signaling factors.2004
- Author(s)
  Ohnishi K. et al.
- Journal Title
  
  Japan.J.Hyperthermic Oncol. 20
  
  Pages: 143-159
- NAID
  10029675920
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Effect of mild temperature hyperthermia and p53 status on the size of hypoxic fractions in sold tumors, with reference to the effect in intratumor quiescent cell populations.2004
- Author(s)
  Masunaga S., Takahashi A., Ohnishi K., Ohnishi T., Nagata K., Suzuki M., Kinashi Y., Ono K.
- Journal Title
  
  International Journal of Radiation Oncology Biology Physics 60
  
  Pages: 570-577
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] Plastic induction of CD133AC133-positive cells in the microenvironment of glioblastoma spheroid
- Author(s)
  Ohnishi K, Tani T, Bando S, Kubota N, Fujii Y, Hatano O, Harada H
- Journal Title
  
  International Journal of Oncology
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659593
[Journal Article] DNA修復関連遺伝子を標的としたRNA干渉によるがん細胞の放射線増感
- Author(s)
  大西健他
- Journal Title
  
  癌の臨床 (印刷中)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] ハイパーサーミアによるがん治療-最近のトピックス
- Author(s)
  大西武雄
- Journal Title
  
  放射線医学研究所放射線科学印刷中
- Data Source
  KAKENHI-PROJECT-12217130
[Journal Article] Heat-induced phosphorylation of NBS1 in human skin fibroblast cells.
- Author(s)
  Ohnishi K., Scuric Z., Yau D., Schiestl R.H., Okamoto N., Takahashi A., Ohnishi T.
- Journal Title
  
  J.Cell.Biochem. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591220
[Journal Article] siRNA Targeted for NBS1 enhances heat sensitivity in human anaplastic thyroid carcinoma cells.
- Author(s)
  Okamoto N, Takahaski A, Ota I, Ohnishi K, Mori E, Kondo N, Noda T, Nakagawa Y, Uemura H, Yane K, Hosoi H, Ohnishi T.
- Journal Title
  
  International Journal of Hyperthermia in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] CLEM imaging of rhododendrol-induced leukoderma in zebrafish and catalytic oxidation of Japanese cedar wood.2020
- Author(s)
  Osamu Hatano, Masumi Hayazaki, Akie Hamamoto, Hiroshi Takemori, Hikaru Takaya, Takafumi Shano, Ken Ohnishi, Masaharu Nakamura.
- Organizer
  ABiS Symposium: Forefront and Future of Electron Microscopic Imaging, Okazaki, Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09887
[Presentation] BNCTがん治療効果の生物学的な増強戦略2019
- Author(s)
  大西健、三澤雅樹
- Organizer
  SATテクノロジー・ショーケース2019
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] LAT1発現増強によるBNCTにおける中性子線増感2019
- Author(s)
  大西健、三澤雅樹、鹿野直人、松本信弘
- Organizer
  第21回菅原・大西記念癌治療増感シンポジウム in 奈良
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] がん細胞選択的なアミノ酸トランスポーターLAT1過剰発現誘導の検討2018
- Author(s)
  大西健、藤田智也、髙﨑真美、松谷早苗、鹿野直人
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] Overexpression of LAT1 by lipofection enhances BPA intracellular incorporation in glioblastoma cells2018
- Author(s)
  Ken Ohnishi, Sanae Matsutani, Naoto Sikano
- Organizer
  The 18th International Congress on Neutron Capture Therapy
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] マウス中枢神経系細胞を用いた脳腫瘍ライブイメージングモデルの開発2018
- Author(s)
  大西　健、相良順一、髙崎真美、鹿野直人
- Organizer
  第20回癌治療増感研究シンポジウム
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] ステロイドホルモンの質量分析イメージング解析とラット副腎皮質の再生2018
- Author(s)
  秦野修、磯崎勝弘、竹森洋、西村裕志、竹田浩之、岩崎哲史、大西健.
- Organizer
  第1回再生学異分野融合研究会　(岡崎市)
- Data Source
  KAKENHI-PROJECT-17K09887
[Presentation] がん細胞あるいはがん幹細胞様細胞選択的なLAT1過剰発現によるBNCTの検討2018
- Author(s)
  大西　健
- Organizer
  茨城大学理学部公開シンポジウム第11回Quantum Medicine研究会
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] SALDIと誘導体化によるステロイドホルモンのイオン化法の改良と質量分析イメージングへの応用2017
- Author(s)
  秦野修、磯崎勝弘、竹森洋、大西健、岩崎哲史、片桐昌直、川崎英也、一柳優子、荒川隆一
- Organizer
  第68回イオン反応研究会/第157回質量分析関西談話会/第6回イオン移動度研究会・合同研究会
- Data Source
  KAKENHI-PROJECT-17K09887
[Presentation] SALDI と誘導体化によるステロイドホルモンのイオン化法の改良と質量分析イメージングへの応用2017
- Author(s)
  秦野修、磯崎勝弘、竹森洋、大西健、岩崎哲史、片桐昌直、川崎英也、一柳優子、荒川隆一
- Organizer
  第68回イオン反応研究会 / 第157回質量分析関西談話会 / 第6回イオン移動度研究会・合同研究会
- Place of Presentation
  奈良市
- Data Source
  KAKENHI-PROJECT-26670461
[Presentation] がん幹細胞に対するハイパーサーミアの有効性について2017
- Author(s)
  大西　健、坂本裕貴
- Organizer
  第34回日本ハイパーサーミア学会
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] Usefulness of spheroid originated CD133-positive cells for cancer stem cell-targeting radiotherapy.2017
- Author(s)
  Tani T, Sakamoto Y, Fujii Y, Ohnishi K.
- Organizer
  The 7th International Society of Radiation Neurobiology Conference
- Place of Presentation
  越後湯沢
- Year and Date
  2017-02-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] ステロイドホルモンのイオン化法の改良と質量分析イメージングへの応用2016
- Author(s)
  秦野修・磯崎勝弘・竹森洋・大西健・五百崎太輔・森本翔大・一柳優子・川崎英也・片桐昌直・荒川隆一・車谷典男
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  大阪府吹田市
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-26670461
[Presentation] ステロイドホルモンのイオン化法の改良と質量分析イメージングへの応用2016
- Author(s)
  秦野修, 磯崎勝弘, 竹森洋, 大西健, 五百崎太輔, 森本翔大, 一柳優子, 川崎英也, 片桐昌直, 荒川隆一, 車谷典男
- Organizer
  第64回質量分析総合討論会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-26670461
[Presentation] Improvement of Ionization Methods of Steroid Hormones and Application to Imaging Mass Spectrometry.2016
- Author(s)
  Hatano O, Isozaki K, Takemori H, Ohnishi K, Katagiri M, Kawasaki H, Ichiyanagi Y, Arakawa R, Kurumatani N.
- Organizer
  Intl. Symp. of Biological Mass Spectrometry
- Place of Presentation
  Tokyo
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-26670461
[Presentation] HSP90阻害剤AUYによる神経膠芽腫CD133陽性細胞の温熱/放射線増感作用2016
- Author(s)
  谷　俊明、福地　命、大西　健
- Organizer
  日本ハイパーサーミア学会第34回大会
- Place of Presentation
  つくば
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-16K10399
[Presentation] CD133-positive cells emerging in hypoxic microenvironment in glioblastoma spheroids show resistance to X-rays and CDDP.2015
- Author(s)
  Ohnishi K, et al.
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto International Conference Center
- Year and Date
  2015-05-27
- Data Source
  KAKENHI-PROJECT-26670461
[Presentation] ヒト由来細胞とネコ由来細胞の放射線感受性の違い2014
- Author(s)
  藤井義大, 坂東真一, 大西　健, 加藤宝光
- Organizer
  茨城大学理学部公開シンポジウム第7回Quantum Medicine研究会
- Place of Presentation
  水戸
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] スフェロイドに出現すCD133陽性細胞の放射線感受性2014
- Author(s)
  大西健、窪田宜夫、他
- Organizer
  第16回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23591845
[Presentation] スフェロイドに出現するCD133陽性細胞の放射線感受性2014
- Author(s)
  大西　健, 谷　俊明, 坂東真一, 藤井義大, 窪田宜夫, 秦野　修
- Organizer
  第16回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] ヒト由来細胞とネコ由来細胞の放射線感受性の違い2014
- Author(s)
  藤井義大, 坂東真一, 大西健, 加藤宝光
- Organizer
  茨城大学理学部公開シンポジウム第7回Quantum Medicine 研究会
- Place of Presentation
  水戸
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] スフェロイドに発現するCD133陽性細胞の放射線感受性2014
- Author(s)
  大西健、窪田宜夫、他
- Organizer
  第16回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23591845
[Presentation] スフェロイドに出現するCD133 陽性細胞の放射線感受性2014
- Author(s)
  大西健, 谷俊明, 坂東真一, 藤井義大,窪田宜夫, 秦野修
- Organizer
  第16回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] スフェロイドの低酸素微小環境に依存したCD133発現の可塑的変化2013
- Author(s)
  谷　俊明, 坂東真一, 藤井義大, 窪田宜夫, 秦野　修, 大西　健
- Organizer
  第11回がんとハイポキシア研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] グリオブラストーマスフェロイド内低酸素微小環境とCD133陽性細胞の誘導2013
- Author(s)
  大西健, 谷俊明, 坂東真一, 秦野修, 藤井義大, 窪田宜夫
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 神経膠芽腫細胞T98Gの単層培養ースフェロイド間でみられるCD133陽性細胞の可塑的な誘導2013
- Author(s)
  大西健、窪田宜夫、他
- Organizer
  第56回日本放射線影響学会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23591845
[Presentation] 神経膠芽腫細胞T98Gの単層培養―スフェロイド間で見られるCD133陽性細胞の可塑的な誘導2013
- Author(s)
  大西健、窪田宜夫、他
- Organizer
  第56回日本放射線影響学会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23591845
[Presentation] スフェロイドの低酸素微小環境に依存したCD133 発現の可塑的変化2013
- Author(s)
  谷俊明, 坂東真一, 藤井義大, 窪田宜夫,秦野修, 大西健
- Organizer
  第11回がんとハイポキシア研究会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 神経膠芽腫細胞T98Gの単層培養⇔スフェロイド培養間で見られるCD133 陽性細胞の可塑的な誘導2013
- Author(s)
  大西健, 谷俊明, 坂東真一, 藤井義大,窪田宜夫, 秦野修
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] グリオブラストーマスフェロイド内低酸素微小環境とCD133陽性細胞の誘導2013
- Author(s)
  大西健、窪田宜夫、他
- Organizer
  第72回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23591845
[Presentation] 神経膠芽腫細胞T98Gの単層培養⇔スフェロイド培養間で見られるCD133陽性細胞の可塑的な誘導2013
- Author(s)
  大西　健, 谷　俊明, 坂東真一, 藤井義大, 窪田宜夫, 秦野　修
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  青森
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] スフェロイドを用いたCD133陽性細胞の解析2013
- Author(s)
  大西　健，坂東真一，窪田宜夫，秦野　修，谷　俊明
- Organizer
  第15回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] スフェロイドを用いたCD133 陽性細胞の解析2013
- Author(s)
  大西健,坂東真一,窪田宜夫,秦野修,谷俊明
- Organizer
  第15回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] フラボノイドA に新規に見出された放射線増感の作用機序2012
- Author(s)
  坂東真一,秦野修,竹森洋,窪田宜夫,大西健
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 新規Hsp90阻害剤PU-H71のDNA二重鎖切断修復抑制による放射線増感2012
- Author(s)
  瀬川達矢，田中彩，坂東真一，松本孔貴，岡安隆一，大西　健，窪田宜夫
- Organizer
  第50回日本放射線腫瘍学会　生物部会学術大会
- Place of Presentation
  沖縄
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] フラボノイド3’,5,7-Trihydroxy-3,4’-Dimethoxyflavoneに新規に見出されたがん細胞優位な細胞致死作用2012
- Author(s)
  大西　健，坂東真一，秦野　修，竹森　洋，窪田宜夫
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] フラボノイドTHDF に新規に見出されたがん細胞優位な細胞致死作用2012
- Author(s)
  坂東真一, 秦野修, 竹森洋, 窪田宜夫,大西健
- Organizer
  第14回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] フラボノイドTHDFに新規に見出されたがん細胞優位な細胞致死作用2012
- Author(s)
  坂東真一, 秦野修, 竹森洋, 窪田宜夫, 大西健
- Organizer
  第14回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 植物由来フラボノイドA に新規に見出されたがん細胞優位な放射線増感作用2012
- Author(s)
  坂東真一,秦野修,竹森洋,窪田宜夫,大西健
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] フラボノイド3 ' ,5,7-Trihydroxy-3,4 '-Dimethoxyflavone に新規に見出されたがん細胞優位な細胞致死作用2012
- Author(s)
  大西健,坂東真一,秦野修,竹森洋,窪田宜夫
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 新規Hsp90 阻害剤PU-H71 の放射線増感メカニズムについて2012
- Author(s)
  瀬川達矢,田中彩, 坂東真一, 大西健,窪田宜夫
- Organizer
  第14回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] Screening of phytochemicals sensitizing heat sensitivity of cancer cells2012
- Author(s)
  Bando S, Hatano O,Takemori H,Kubota N,Ohnishi K
- Organizer
  The 11th International Congress of Hyperthermic Oncology & The 29 th Japanese Congress of Thermal Medicine (ICHO&JCTM 2012)
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 新規Hsp90 阻害剤PU-H71の放射線増感メカニズムについて2012
- Author(s)
  瀬川達矢，田中彩, 坂東真一, 大西健, 窪田宜夫
- Organizer
  第14回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] フラボノイドAに新規に見出された放射線増感の作用機序2012
- Author(s)
  坂東真一，秦野　修，竹森　洋，窪田宜夫，大西　健
- Organizer
  日本放射線影響学会　第55回大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] Screening of phytochemicals sensitizing heat sensitivity of cancer cells2012
- Author(s)
  Shin-ichi Bando,Osamu Hatano,Hiroshi Takemori,Nobuo Kubota,Ken Ohnishi
- Organizer
  The 11th International Congress of Hyperthermic Oncology & The 29 th Japanese Congress of Thermal Medicine (ICHO&JCTM 2012)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2012-08-29
- Data Source
  KAKENHI-PROJECT-22591015
[Presentation] Screening of phytochemicals sensitizing heat sensitivity of cancer cells2012
- Author(s)
  Shin-ichi Bando，Osamu Hatano，Hiroshi Takemori，Nobuo Kubota，Ken Ohnishi
- Organizer
  The 11th International Congress of Hyperthermic Oncology & The 29 th Japanese Congress of Thermal Medicine
- Place of Presentation
  Kyoto
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 植物由来フラボノイドAに新規に見出されたがん細胞優位な放射線増感作用2012
- Author(s)
  坂東真一，秦野　修，竹森　洋，窪田宜夫，大西　健
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 新規Hsp90阻害剤PU-H71 のDNA 二重鎖切断修復抑制による放射線増感2012
- Author(s)
  瀬川達矢,田中彩,坂東真一,松本孔貴,岡安隆一,大西健,窪田宜夫
- Organizer
  第50回日本放射線腫瘍学会生物部会学術大会
- Place of Presentation
  宜野湾
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] 植物由来の新規放射線増感物質はがん細胞により強い増感作用を示す2011
- Author(s)
  坂東真一, 秦野修, 竹森洋, 窪田宜夫,大西健
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] Screening of flavonoids sensitizing radiation sensitivity of cancer cells2011
- Author(s)
  Ken Ohnishi, Shin-ichi Bando, Noboru Kubota, Hiroshi Takemori, Osamu Hatano
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Warsaw, Poland
- Year and Date
  2011-08-30
- Data Source
  KAKENHI-PROJECT-22591015
[Presentation] 放射線増感作用を示す植物生理活性物質、特にフラボノイドの分子標的放射線増感剤としての有用性2011
- Author(s)
  大西健
- Organizer
  第13回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] Screening of flavonoids sensitizing radiation sensitivity of cancer cells.2011
- Author(s)
  Ohnishi K, Bando S, Kubota N, Takemori H, Hatano O.
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Poland, Warsaw
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] Hsp90 阻害剤Celastrol のヒト腫瘍細胞の放射線増感とp53 status2011
- Author(s)
  瀬川達矢, 田中彩, 坂東真一, 大西健,窪田宜夫
- Organizer
  日本放射線腫瘍学会第24回大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] Hsp90阻害剤Celastrolのヒト腫瘍細胞の放射線増感とp53 status2011
- Author(s)
  瀬川達矢, 田中彩, 坂東真一, 大西健, 窪田宜夫
- Organizer
  日本放射線腫瘍学会第24回大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] Screening of flavonoids sensitizing radiation sensitivity of cancer cells2011
- Author(s)
  Ohnishi K, Bando S, Kubota N, Takemori H, Hatano O
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  Poland, Warsaw
- Data Source
  KAKENHI-PROJECT-23659593
[Presentation] がん細胞の放射線感受性とがん抑制遺伝子p532011
- Author(s)
  大西健
- Organizer
  茨城大学理学部公開シンポジウム(第4回Quantum Medicine研究会)茨城大学研究推進プロジェクト「がん放射線治療に関する生命基礎研究」
- Place of Presentation
  茨城
- Year and Date
  2011-02-05
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 増感剤としての有用性放射線増感作用を示す植物生理活性物質、特にフラボノイドの分子標的放射線2011
- Author(s)
  大西健
- Organizer
  第13回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 「きぼう」での宇宙実験Rad Gene報告2:低線量宇宙放射線被ばくの証拠-DSBの飛跡と放射線適応応答-2010
- Author(s)
  大西武雄
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Aim, preparation and fight in Rad Gene/LOH space experiments2010
- Author(s)
  大西武雄
- Organizer
  5th NIRS Int Open Lab Workshop
- Place of Presentation
  千葉
- Year and Date
  2010-01-13
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 抗がん作用を持つフラボノイド類のスクリーニング2010
- Author(s)
  大西健
- Organizer
  日本放射線影響学会第53回大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] Space experiment "Rad Gene"-report ; Detection of DNA damage and adaptive response activity of human cells exposed to space radiations2010
- Author(s)
  Ohnishi T.
- Organizer
  38th COSPAR
- Place of Presentation
  Bremen (Germany)
- Year and Date
  2010-07-21
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Reports of "Rad Gene"-space radiation effects on human cells-2010
- Author(s)
  大西武雄
- Organizer
  5th NIRS Int Open Lab Workshop
- Place of Presentation
  千葉
- Year and Date
  2010-01-13
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Space experiment "Rad Gene"-report : DNA damage and adaptive response in human cells exposed to space radiations.2010
- Author(s)
  Ohnishi T.
- Organizer
  56^<th> Ann Meeting Radiat.Res.Society
- Place of Presentation
  Maui, Hawaii (USA)
- Year and Date
  2010-09-26
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 宇宙放射線による放射線適応応答2010
- Author(s)
  大西武雄
- Organizer
  第49回日本医学放射線学会生物部会学術大会
- Place of Presentation
  ホテルさっぽろ芸文館(北海道)
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 「きぼう」での Rad Gene 宇宙実験報告32010
- Author(s)
  大西武雄
- Organizer
  第26回宇宙利用シンポジウム
- Place of Presentation
  相模原
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 刺激のクロストーク;あらかじめの温熱や放射線刺激は放射線抵抗性や温熱耐性をもたらす2009
- Author(s)
  大西武雄
- Organizer
  日本ハイパーサーミア学会第26回大会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] The role of a tumor suppressor gene product, p53, in space environment2009
- Author(s)
  大西武雄
- Organizer
  日本マイクログラビティ応用学会第24回学術講演会
- Place of Presentation
  那覇
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 宇宙ステーションにおける宇宙放射線の生物影響研究-2-2009
- Author(s)
  大西武雄
- Organizer
  第25回宇宙利用シンポジウム
- Place of Presentation
  相模原市
- Year and Date
  2009-01-14
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Cell death induced by high LET and low LET radiations2009
- Author(s)
  大西武雄
- Organizer
  2nd Asian Congr Radiat Res
- Place of Presentation
  Seoul, Korea
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] ISS-Rad Gene report 2 : Detection of space radiation-induced DNA damage in cell nuclei by γH2AX positive foci staining2009
- Author(s)
  大西武雄
- Organizer
  日本宇宙生物科学会第23回大会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Tween80 enhances heat-induced arrest of cell proliferation through regulating Akt and NBS1 signaling pathways.2008
- Author(s)
  Ohnishi K
- Organizer
  10th Int Congr Hyperthermic Oncol.
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 界面活性剤Tween80と温熱の併用処理による細胞増殖抑制のメカニズム2008
- Author(s)
  大西健
- Organizer
  第47回日本医学放射線学会生物部会学術大会
- Place of Presentation
  高知市
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 放射線生物研究センターと放射線生物研究連絡会議の歴史2008
- Author(s)
  大西武雄
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Tween80 enhances heat-induced arrest of cell proliferation through regulating AKT and NBS1 signaling pathways.2008
- Author(s)
  Ohnishi K
- Organizer
  10^<th> International Congress on Hyperthermic Oncology.
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] p53C末端ペプチドと放射線併用による変異型p53保有移植腫瘍の増殖抑制2008
- Author(s)
  大西健
- Organizer
  第14回癌治療増感研究会
- Place of Presentation
  鈴鹿市
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] Tween80 enhances heat-induced arrest of cell proliferation through regulating AKT and NBS1 signaling pathways2008
- Author(s)
  Ohnishi K
- Organizer
  10^<th> International Congress on Hyperthermic Oncology
- Place of Presentation
  Munich, Germany
- Year and Date
  2008-04-11
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 宇宙放射線防護をめざして2008
- Author(s)
  Ohnishi, T
- Organizer
  日本放射線防護研究会
- Place of Presentation
  Kyoto
- Year and Date
  2008-06-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 研究発表-総括総合評価2008
- Author(s)
  大西武雄
- Organizer
  群馬大学第4回COE国際シンポジウム
- Place of Presentation
  前橋市
- Year and Date
  2008-11-17
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Phospho-Nbsl and Mrell proteins which recognize DSBsco-localize with γH2AX in the nucleus after heat treatment.2008
- Author(s)
  Ohnishi T
- Organizer
  The International Ataxia-telangiectasia Workshop 2008
- Place of Presentation
  Ohtsu, Japan
- Year and Date
  2008-04-22
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 界面活性剤Tween80と温熱の併用処理による細胞増殖抑制のメカニズム2008
- Author(s)
  大西健
- Organizer
  第47回日本医学放射線学会生物部会学術大会
- Place of Presentation
  高知市
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] Localization of DSB-recognizing proteins in the nucleus after heat treatment2008
- Author(s)
  Ohnishi T
- Organizer
  10^<th> International Congress on Hyperthermic Oncology
- Place of Presentation
  Munich, Germany
- Year and Date
  2008-04-10
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 宇宙ステーションにおける宇宙放射線の生物影響研究2008
- Author(s)
  Ohnishi, T
- Organizer
  The 24th Space Utilization Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2008-01-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Molecular chaperon therapy against human cancer cells.2008
- Author(s)
  Ohnishi T
- Organizer
  4th Int Congr Stress Resp Biol Med.
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 分子シャペロンp53C末端ペプチドと放射線併用による変異型p53腫瘍の増殖遅延2008
- Author(s)
  大西健
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-19
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Development of thermotolerance requires interaction between polymerase β and heat shock proteins2008
- Author(s)
  Ohnishi T., et. al.
- Organizer
  12th Biennial National Conference of Indian Association of Hyperthermic Oncol.Med
- Place of Presentation
  Patna,India
- Year and Date
  2008-02-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Tween80 enhances heat-induced arrest of cell proliferation through regulating AKT and NBSI signaling pathways2008
- Author(s)
  Ohnishi K
- Organizer
  10^<th> International Congress on Hyperthermic Oncology
- Place of Presentation
  Munich, Germany
- Year and Date
  2008-04-11
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 放射線感受性・温熱感受性とp53およびHsp702008
- Author(s)
  大西武雄
- Organizer
  第17回日本癌病態治療研究会
- Place of Presentation
  京都市
- Year and Date
  2008-06-26
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] がん抑制遺伝子p53を標的としたがん治療増感2008
- Author(s)
  大西武雄
- Organizer
  第14回癌治療増感研究会
- Place of Presentation
  鈴鹿市
- Year and Date
  2008-06-07
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 放射線と生命とのかかわりあい-そのベネフィットをさらに伸ばし文明の利器とする-2008
- Author(s)
  大西武雄
- Organizer
  第3回高崎量子応用研究シンポジウム
- Place of Presentation
  高崎市
- Year and Date
  2008-10-09
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] p53C末端ペプチドと放射線併用による変異型p53保有移植腫瘍の増殖抑制2008
- Author(s)
  大西健
- Organizer
  第14回癌治療増感研究会
- Place of Presentation
  鈴鹿市
- Year and Date
  2008-06-08
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 温熱誘導DNA二本鎖切断の生物学2008
- Author(s)
  大西武雄
- Organizer
  日本ハイパーサーミア学会第25回大会
- Place of Presentation
  名古屋市
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 分子シャペロンp53C末端ペプチドと放射線併用による変異型p53腫瘍の増殖遅延2008
- Author(s)
  大西健
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 宇宙放射線防護をめざして2008
- Author(s)
  大西武雄
- Organizer
  日本放射線防護研究会
- Place of Presentation
  京都
- Year and Date
  2008-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] The p53-dependent radioadaptive response.2008
- Author(s)
  Ohnishi T
- Organizer
  37th COSPAR
- Place of Presentation
  Montreal, Canada
- Year and Date
  2008-07-13
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 宇宙ステーションにおける宇宙放射線の生物影響研究.2008
- Author(s)
  大西武雄
- Organizer
  第24回宇宙利用シンポジウム
- Place of Presentation
  日本科学未来館,東京
- Year and Date
  2008-01-18
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線適応応答のしくみ2008
- Author(s)
  大西武雄
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-20
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 生・死のシグナルトランスダクションを標的としたがん治療(放射線・温熱・制がん剤)2008
- Author(s)
  大西武雄
- Organizer
  第47回日本医学放射線学会生物部会学術大会
- Place of Presentation
  高知市
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] Localization of DSB-recognizing proteins in the nucleus after heat treatment2008
- Author(s)
  Ohnishi T
- Organizer
  10^<th> International Congress on Hyperthermic Oncology
- Place of Presentation
  Munich, Germany
- Year and Date
  2008-04-10
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] Localization of DSB-recognizing proteins in the nucleus after heat treatment.2008
- Author(s)
  Ohnishi T
- Organizer
  10^<th> International Congress on Hyperthermic Oncology.
- Place of Presentation
  Munich, Germany
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 界面活性剤Tween80と温熱の併用処理による細胞増殖抑制のメカニズム2008
- Author(s)
  大西健
- Organizer
  第47回日本医学放射線学会生物部会学術大会
- Place of Presentation
  高知市
- Year and Date
  2008-06-21
- Data Source
  KAKENHI-PROJECT-20591502
[Presentation] 宇宙ステーションにおける宇宙放射線の生物影響研究2008
- Author(s)
  大西武雄
- Organizer
  第24回宇宙利用シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-01-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Development of thermotolerance requires interaction betwee polymerase β and heat shock-proteiris2008
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  12th Biennial National Conference of Indian Association of Hyperthermic Oncol.Med
- Place of Presentation
  Patna, India
- Year and Date
  2008-02-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線生物学の基礎.がんプロフェッショナル2008
- Author(s)
  Ohnishi, T
- Organizer
  近畿大学特別講演
- Place of Presentation
  Osaka
- Year and Date
  2008-05-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] p53遺伝子の機能から見た放射線生物学2008
- Author(s)
  大西武雄
- Organizer
  日本放射線影響学会第51回大会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-21
- Data Source
  KAKENHI-PROJECT-20659194
[Presentation] 放射線生物学の基礎.がんプロフェッショナル2008
- Author(s)
  大西武雄
- Organizer
  近畿大学特別講演
- Place of Presentation
  大阪
- Year and Date
  2008-05-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 環境ストレス応答遣伝子とその発現機構-タンパグ質のリツ酸化を中心に2007
- Author(s)
  大西武雄
- Organizer
  太陽紫外線防護委員会プロジェクトグループ
- Place of Presentation
  京都
- Year and Date
  2007-04-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 変異型p53に優位なXIAP標的siRNAによる放射線誘発アポトーシスの増強2007
- Author(s)
  大西健, et. al.
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80と温熱の併用による細胞増殖停止のメカニズム.2007
- Author(s)
  大西健, et. al.
- Organizer
  第13回癌治療増感研究会
- Place of Presentation
  前橋テルサ,群馬
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Gene expression of p53-regulated genes in mammalian cultured cells after exposure to space environment2007
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  18th Annual NASA Space Radiation Investigators' Workshop
- Place of Presentation
  Sonoma, USA
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] DNA損傷とその修復-その舞台裏を照らすマイクロビーム2007
- Author(s)
  大西武雄
- Organizer
  マイクロビーム細胞照射装置を用いた放射線に対する細胞応答に関ずるワークショップ
- Place of Presentation
  つくば
- Year and Date
  2007-08-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siR場NAによって変異型P53がん細胞で効率的に増強される放射線誘導アポトーシス2007
- Author(s)
  大西健, et. al.
- Organizer
  第37回日本医学放射線学会生物部会学術大会
- Place of Presentation
  筑波
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] DNA損傷とその修復-その舞台裏を照らすマイクロビーム2007
- Author(s)
  Ohnishi, T
- Organizer
  マイクロビーム細胞照射装置を用いた放射線に対する細胞応答に関するワークショップ
- Place of Presentation
  つくば
- Year and Date
  2007-08-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80と温熱の併用による細胞増殖停止のメカニズム2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  13th Annual Meeting on the Sensitization of Cancer Treatment
- Place of Presentation
  Maebashi
- Year and Date
  2007-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 宇宙放射線を知るー安全な宇宙飛行のためにそして癌治療に生かす2007
- Author(s)
  Ohnishi, T
- Organizer
  第27回日本医学会総会
- Place of Presentation
  Osaka
- Year and Date
  2007-04-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Involvement of NBS1 to cancer cell growth arrest by combined treatment of Tween80 and heat2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 24th Annual Meeting of The Japanese Society of Hyperthermic Oncology
- Place of Presentation
  Tsukuba
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radiation-inducedd adaptive response and genoraic instability2007
- Author(s)
  Ohnishi T., et. al.
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Heat-induced DNA, strand breaks and their repairMeeting, International2007
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  8th ICHS. Annual-Convention & 4th Biennial National Association of Hyperthermic Oncol. Med
- Place of Presentation
  Mumbai, India
- Year and Date
  2007-01-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Gene expression of p53-regulated genes in mammalian cultured cells after exposure to space enviromnent2007
- Author(s)
  Ohnishi T, et. al.
- Organizer
  18th Annual NASA Space Radiation Investigators' Workshop
- Place of Presentation
  Sonoma,USA
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 変異型p53に優位なXIAP的siRNAによる放射線誘発アポトーシスの増強.2007
- Author(s)
  大西健, et. al.
- Organizer
  第66回日本癌学会
- Place of Presentation
  パシフィコ横浜,横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Mutated p53-dominant enhancement of radiation-induced apoptosis by XIAP-siRNA2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAP標的siRINAによって変異型p53がん細胞で効率的に増強される放射線誘導アポトーシス.2007
- Author(s)
  大西健, et. al.
- Organizer
  第37回日本医学放射線学会生物部会学術大会
- Place of Presentation
  つくば国際会議揚,筑波
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] UNSCEARに期待すること2007
- Author(s)
  大西武雄
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] サカサナマズではIGでもμGでも背光反射は見られない.2007
- Author(s)
  大西健, et. al.
- Organizer
  第21回日本宇宙生物科学会
- Place of Presentation
  お茶の水女子大学,東京
- Year and Date
  2007-09-28
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Requirement to UNSCEAR2007
- Author(s)
  Ohnishi, T
- Organizer
  The 50th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Chiba
- Year and Date
  2007-11-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Involvement of NBS1 to cancer cell growth arrest by combined treatment of Tween80 and heat2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 24th Annual Meeting of The Japanese Society of Hyperthermic Oncology
- Place of Presentation
  Maebashi
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80と温熱の併用による細胞増殖停止のメカニズム2007
- Author(s)
  大西健, et. al.
- Organizer
  第13回癌治療増感研究会
- Place of Presentation
  前橋
- Year and Date
  2007-05-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] siRNA targeting NBS1 increases radiation sensitivity of human cancer cells in a p53-independent manner2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-07-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] ストレス応答遺伝子とその発現機構-タンパク質のリン酸化を申心に-2007
- Author(s)
  Ohnishi, T
- Organizer
  太陽紫外線防護委員会プロジェクトグループ
- Place of Presentation
  Kyoto
- Year and Date
  2007-04-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 変異型p53に優位なXLAP標的的siRNAによる放射線誘発アポトーシスの増強.2007
- Author(s)
  大西健, et. al.
- Organizer
  第66回日本癌学会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] siRNA targeting NBS1 increases radiation sensitivity of human cancer cells in a P53-independent manner2007
- Author(s)
  Ohnishi K., et. al.
- Organizer
  13rd International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-11
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAP標的siRNAによって変異型p53がん細胞で効率的に増強される放射線誘導アポトーシス2007
- Author(s)
  大西健, et. al.
- Organizer
  第37回日本医学放射線学会生物部会学術大会
- Place of Presentation
  筑波
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAP標的siRNAによって変異型p53がん細胞で効率的に増強される放射線誘導アポトーシス.2007
- Author(s)
  大西健, et. al.
- Organizer
  第37回日本医学放射線学会生物部会学術大会
- Place of Presentation
  つくば国際会議場,筑波
- Year and Date
  2007-07-21
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Gene expression of P53-regulated genes in mammalian cultured cell after exposure to space environment.2007
- Author(s)
  Ohnishi T, et. al.
- Organizer
  18th Annual NASA Space Radiation in Investigators'Workshop
- Place of Presentation
  Sonoma,USA
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] siRNA targeting NBS1 increases radiation sensitivity of human cancer cells in a p53-independent manner2007
- Author(s)
  Ohnishi K., et. al.
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Tween 80と温熱併用処理によるがん細胞増殖停止へのNBS1の関与.2007
- Author(s)
  大西健, et. al.
- Organizer
  第24回日本ハイパーサーミア学会
- Place of Presentation
  前橋テルサ,群馬
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Tween80と温熱併用処理によるがん細胞増殖停止へのNBS1の関与.2007
- Author(s)
  大西健, et. al.
- Organizer
  第24回日本ハイパーサーミア学会
- Place of Presentation
  前橋テルサ,群馬
- Year and Date
  2007-09-15
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Reconstruction and future project in space radiation science2007
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  The 50th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Chiba
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線と生命とのかかわりあい-放射線、放射能の大切さとそれらを上手に使う方法2007
- Author(s)
  大西武雄
- Organizer
  近畿放射線治療技師の会-かたろう会
- Place of Presentation
  三田
- Year and Date
  2007-06-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的s1RNAによって誘導される変異型p53がん細胞の放射線増感とp53タンパク質の転写活性異常との関係2007
- Author(s)
  大西健, et. al.
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Gene expression of p53-regulated genes in mammalian cultured cells after exposure to space environment.2007
- Author(s)
  Ohnishi T, et. al.
- Organizer
  18th Annual NASA Space Radiation Investiators' Workshop
- Place of Presentation
  Sonoma,USA
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Gene expression of p53-regulated genes in mammalian cultured cells after exposure to space environment2007
- Author(s)
  Ohnishi T., et. al.
- Organizer
  18th Annual NASA Space Radiation Investigators' Workshop
- Place of Presentation
  Sonoma,USA
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Heat-induced DNA strand breaks and their repair2007
- Author(s)
  Ohnishi T., et. al.
- Organizer
  8th ICHS Annual-Convention & 4th Biennial National Meeting, International Association of Hyperthermic Oncol. Med
- Place of Presentation
  Mumbai,India
- Year and Date
  2007-01-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radiation-induced adaptive response and genomic instability2007
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-07-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Tween80と温熱併用処理によるがん細胞増殖停止へのNBS1の関与2007
- Author(s)
  大西健, et. al.
- Organizer
  日本ハイパーサーミア学会第24回大会
- Place of Presentation
  前橋
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] siRNA targeting NBS1 increases radiation sensitivity of human cancer cells in a p53-independent manner2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  13th International Congress of Radiation Research
- Place of Presentation
  San Francisco, USA
- Year and Date
  2007-07-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 宇宙放射線研究の再構築とその展望2007
- Author(s)
  大西武雄, et. al.
- Organizer
  日本放射線影響学会第50回大会
- Place of Presentation
  千葉
- Year and Date
  2007-11-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radiation-induced adaptive response and genomic instability2007
- Author(s)
  Ohnishi T, et. al.
- Organizer
  13rd International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAP標的siRiNAによって誘導される変異型p53がん細胞の放射線増感と53タンパク質の転写活性異常との関係.2007
- Author(s)
  大西健, et. al.
- Organizer
  第50回日本放射線影響学会
- Place of Presentation
  幕張メッセ,千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] IXAP標的siRNAによって変異型p53がん細胞で効率的に増強される放射線誘導アポトーシス2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第37日本医学放射線学会生物部会学術大会
- Place of Presentation
  Tsukuba
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80と温熱の併用による細胞増殖停止のメカニズム.2007
- Author(s)
  大西健, et. al.
- Organizer
  第13回癌治療増感研究会
- Place of Presentation
  前橋テルサ,群馬
- Year and Date
  2007-05-19
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNAによって変異型p53がん細胞で効率的に増強される放射線誘導アポトーシス2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第37向日本医学放射線学会生物部会学術大会
- Place of Presentation
  Tsukuba
- Year and Date
  2007-07-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Relation between radiation sensitization and dysfunction of p53 as a transcription factor in mutated p53 cancer cells by siRNA targeting XIAP2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 50th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Chiba
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Mutated p53-dominant enhancement of radiation-induced apoptosis by XIAP-siRNA2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNAによって誘導される変異型p53がん細胞の放射線増感とp53タンパク質の転写活性異常との関係2007
- Author(s)
  大西健, et. al.
- Organizer
  第50回日本放射線影響学会
- Place of Presentation
  千葉
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80と温熱の併用による細胞増殖停止のメカニズム2007
- Author(s)
  大西健, et. al.
- Organizer
  第13回癌治療増感研究会
- Place of Presentation
  前橋
- Year and Date
  2007-05-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Radiation-induced adaptive response and genomic instability.2007
- Author(s)
  Ohnishi T, et. al.
- Organizer
  13rd International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-12
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80と温熱の併用による細胞増殖停止のメカニズム2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  13th Annual Meeting on the Sensitization of Cancer Treatment
- Place of Presentation
  Maebashi
- Year and Date
  2007-05-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Relation between radiation sensitization and dysfunction of p53 as a transcription factor in mutated p53 cancer cells by siRNA targeting XIAP2007
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 50th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Chiba
- Year and Date
  2007-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 放射線と生命とのかかわり, あい-放射線・放射能の大切ざとそれらを上手に使う方法-2007
- Author(s)
  Ohnishi, T
- Organizer
  近畿放射線治療技師の会-かたろう会
- Place of Presentation
  Sanda
- Year and Date
  2007-06-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] siRNA targeting NBS1 increases radiation sensitivity of human cancer cells in a p53-independent manner2007
- Author(s)
  Ohnishi K., et. al.
- Organizer
  13rd International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 変異型p53に優位なXIAP標的siRNAによる放射誘発アポトーシスの増強2007
- Author(s)
  大西健, et. al.
- Organizer
  第66回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Tween80と温熱併用処理によるがん細胞増殖停止へのNBS1の関与2007
- Author(s)
  大西健, et. al.
- Organizer
  第24回日本ハイパーサーミア学会
- Place of Presentation
  前橋
- Year and Date
  2007-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Radiation-induced adaptive response and genomic instability.2007
- Author(s)
  Ohnishi T, et. al.
- Organizer
  13rd International Congress of Radiation Research
- Place of Presentation
  San Francisco,USA
- Year and Date
  2007-07-12
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNA によって誘導される変異型p53がん細胞の放射線増感とp53タンパク質の転写活性異常との関係.2007
- Author(s)
  大西健, et. al.
- Organizer
  第50回日本放射線影響学会
- Place of Presentation
  幕張メッセ,千葉
- Year and Date
  2007-11-15
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 日本放射線影響学会として行っている社会への啓発活動2007
- Author(s)
  大西武雄
- Organizer
  放射線取扱い主任者部会年次大会
- Place of Presentation
  札幌
- Year and Date
  2007-10-04
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNAによる放射線増感2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  8th Symposium on Sensitilation of Cancer Treatment in Nara
- Place of Presentation
  Nara
- Year and Date
  2006-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽・地球・生命-放射線と生命とのかかわりあい2006
- Author(s)
  Ohnishi, T
- Organizer
  国立循環器センターRI講習会
- Place of Presentation
  Osaka
- Year and Date
  2006-06-09
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radiation sensitization by siRNA-targeted for XIAP in human lung cancer cells2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAP標的siRNAによるヒト非小細胞肺がん細胞の放射線増感2006
- Author(s)
  大西健, et. al.
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radiation sensitization by siRNA targeting XLAP in human lung cancer cells2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 49th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Sapporo
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radioadaptive response by pre-irradiation at a low dose-rate2006
- Author(s)
  Ohnishi T., et. al.
- Organizer
  9th World Congress of Nuclear Medicine and Biology
- Place of Presentation
  Seoul,Korea
- Year and Date
  2006-10-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Phosphorylation of DNA damage-recognizing proteins at heavy-ion track2006
- Author(s)
  Ohnishi T., et. al.
- Organizer
  36th COSPAR
- Place of Presentation
  Beijing,China
- Year and Date
  2006-07-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 頭頸部癌における分子生物学の貢献2006
- Author(s)
  Ohnishi, T
- Organizer
  第30回日本頭頸部癌学会, 教育講演
- Place of Presentation
  Osaka
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 哺乳類培養細胞における宇宙環境曝露後のp53調節遺伝子群の遺伝子発現2006
- Author(s)
  大西武雄
- Organizer
  日本放射線影響学会第49回大会
- Place of Presentation
  札幌
- Year and Date
  2006-09-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽・地球・生命-がん研究から宇宙科学へ-2006
- Author(s)
  Ohnishi, T
- Organizer
  OPTA粒子線がん治療セミナー
- Place of Presentation
  Osaka
- Year and Date
  2006-11-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽・地球・生命-放射線と生命とのかかわりあい2006
- Author(s)
  Ohnishi, T
- Organizer
  JAXAイブニングセミナー
- Place of Presentation
  Tsukuba
- Year and Date
  2006-03-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 重粒子線がん治療は夢の玲療2006
- Author(s)
  大西武雄
- Organizer
  OPTA公開シンポジウム, 教育講演
- Place of Presentation
  大阪
- Year and Date
  2006-09-02
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNAによる放射線増感2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  8th Symposium on Sensitization of Cancer Treatment in Nara
- Place of Presentation
  Nara
- Year and Date
  2006-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] The p53 gene status and new p53-targeted therapies of chemical chaperons and high LET radiations for cancer2006
- Author(s)
  Ohnishi T., et. al.
- Organizer
  BAERI Symposium
- Place of Presentation
  Seoul,Korea
- Year and Date
  2006-03-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Heat sensitization by targeting heat-induced cell survival signaling tran sduction through Akt2006
- Author(s)
  Ohnishi K., et. al.
- Organizer
  The 4th Asian Congress of Hyperthermic Oncology
- Place of Presentation
  Nara
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Radiation sensitization by siRNA targeting XIAP in human lung cancer cells2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 49th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Sapporo
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 宇宙放果線研究の再構築とその展望2006
- Author(s)
  大西武雄, et. al.
- Organizer
  第22回宇宙利用シンポジウム
- Place of Presentation
  東京
- Year and Date
  2006-01-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Heat sensitization by targeting heat-induced cell survival signaling transduction through Akt2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 4th Asian Congress of Hyperthermic Oncology
- Place of Presentation
  Nara
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80併用で増強される温熱による腫瘍増殖抑制2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第45回日本医学放射線学会生物部会学術大会
- Place of Presentation
  Hirosaki
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNAによるヒト非小細胞肺がん細胞の放射線増感2006
- Author(s)
  大西健, et. al.
- Organizer
  第65回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAPを標的としたsiRNAによるヒト肺がん細胞の放射線増感2006
- Author(s)
  大西健, et. al.
- Organizer
  第49回日本放射線影響学会
- Place of Presentation
  札幌
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80と温熱を併用した腫瘍増殖抑制効果2006
- Author(s)
  大西健, et. al.
- Organizer
  第8回関西ハイパーサーミア研究会、第15回高温度療法臨床研究会合同研究会
- Place of Presentation
  大阪
- Year and Date
  2006-06-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Heat sensitization by targeting heat-induced cell survival signaling transduction through Akt2006
- Author(s)
  Ohnishi K., et. al.
- Organizer
  The 4th Asian Congress of Hyperthermic Oncology
- Place of Presentation
  Nara
- Year and Date
  2006-09-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] The p53 gene status and new p53-targeted therapies of chemical chaperons and high LET radiations for cancer2006
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  BAERI Symposium
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-03-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Phosphorylation of DNA damage-recognizing proteins at heavy-ion track2006
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  36th COSPAR
- Place of Presentation
  Beijing, China
- Year and Date
  2006-07-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80併用で増強される温熱による腫瘍増殖抑制2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第43回日本医学放射線学会生物部会学術大会
- Place of Presentation
  Hkosaki
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] XIAP標的siRNAによる放射線増感2006
- Author(s)
  大西健, et. al.
- Organizer
  第8回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2006-02-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80と温熱を併用した腫瘍増殖抑制効果2006
- Author(s)
  大西健, et. al.
- Organizer
  第8回関西ハイパーサーミア研究会・第15回高温度療法臨床研究会合同研究会
- Place of Presentation
  大阪
- Year and Date
  2006-06-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 太陽、地球、生命-放射線と生命とのかかわりあい2006
- Author(s)
  大西武雄
- Organizer
  JAXAイブニングセミナー
- Place of Presentation
  筑波
- Year and Date
  2006-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 宇宙放射線研究の再構築とその展望2006
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  The 22nd Space Utilization Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2006-01-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radioadaptive response by pre-irradiation at a low dose-rate2006
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  9th World Congress of Nuclear Medicine and Biology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2006-10-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線と生命とのかかわり-医学研究から宇宙研究へ-2006
- Author(s)
  Ohnishi, T
- Organizer
  19th Japanese Society for Therapeutic Radiology and Oncology, 教育講演
- Place of Presentation
  Sendai
- Year and Date
  2006-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAP標的siRNAによる放射線増感2006
- Author(s)
  大西健, et. al.
- Organizer
  第8回癌治療増感研究シンポジウム
- Place of Presentation
  奈良
- Year and Date
  2006-02-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 重粒子線がん治療は夢の治療2006
- Author(s)
  Ohnishi, T
- Organizer
  OPTA公開シンポジウム, 教育講演
- Place of Presentation
  Osaka
- Year and Date
  2006-09-02
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 頭頸部癌における分子生物学の貢献2006
- Author(s)
  大西武雄
- Organizer
  第30回日本頭頸部癌学会, 教育講演
- Place of Presentation
  大阪
- Year and Date
  2006-06-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80併用で増強される温熱による腫瘍増殖抑制2006
- Author(s)
  大西健, et. al.
- Organizer
  第45回日本医学放射線学会生物部会学術大会
- Place of Presentation
  弘前
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 重粒子線誘導トラックにおけるDNA損傷認誌タンパク質の挙動2006
- Author(s)
  大西健, et. al.
- Organizer
  第49回日本放射線影響学会
- Place of Presentation
  札幌
- Year and Date
  2006-09-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] Gene expression of p53-regulated genes in mammalian cultured cells after exposure to space environment2006
- Author(s)
  Ohnishi, T
- Organizer
  The 49th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Sapporo
- Year and Date
  2006-09-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] XIAPを標的としたsiRNAによるヒト肺がん細胞の放射線増感2006
- Author(s)
  大西健, et. al.
- Organizer
  日本放射線影響学会第49回大会
- Place of Presentation
  札幌
- Year and Date
  2006-09-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Dynamics of DNA damage-recognizing proteins at heavy-ion-induced track2006
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  4th International Workshop of Space Radiation Research and 17th Annual NASA Space Radiation Health Investigators' Workshop
- Place of Presentation
  Petersburg, Russia
- Year and Date
  2006-06-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80と温熱を併用した腫瘍増殖抑制効果2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第8回関西ハイパーサーミア研究会・第15回高温度療法臨床研究会合同研究会
- Place of Presentation
  Osaka
- Year and Date
  2006-06-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Radiation sensitization by siRNA-targeted for MAP in human lung cancer cells2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  65th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama
- Year and Date
  2006-09-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線と生命とのカこかわり-医学研究から宇宙研究へ2006
- Author(s)
  大西武雄
- Organizer
  第19回日本放射線腫瘍学会
- Place of Presentation
  仙台
- Year and Date
  2006-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Dynamics of DNA damage-recognizing proteins at heavy-ion-induced track2006
- Author(s)
  Ohnishi T., et. al.
- Organizer
  4th International Workshop of Space Radiation Research and 17th Annual NASA Space Radiation Health Investigators'Workshop
- Place of Presentation
  Petersburg,Russia
- Year and Date
  2006-06-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽、地球、生命-がん研究から宇宙科学へ2006
- Author(s)
  大西武雄
- Organizer
  OPTA粒子線がん治療セミナー
- Place of Presentation
  大阪
- Year and Date
  2006-11-08
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽、地球、生命-放射線と生命とのかかわりあい2006
- Author(s)
  大西武雄
- Organizer
  国立循環器センターRI講習会
- Place of Presentation
  大阪
- Year and Date
  2006-06-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 界面活性剤Tween80と温熱を併用した腫瘍増殖抑制効果2006
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第8回関西ハイパーサーミア研究会・第15回高温度療法臨床研究会合同研究会
- Place of Presentation
  Osaka
- Year and Date
  2006-06-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] 界面活性剤Tween80併用で増強される温熱による腫瘍増殖抑制2006
- Author(s)
  大西健, et. al.
- Organizer
  第45回日本医学放射線学会生物部会学術大会
- Place of Presentation
  弘前
- Year and Date
  2006-07-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591389
[Presentation] p53遺伝子型に依存する温熱によるがん細胞の放射線増感2005
- Author(s)
  大西武雄, et. al.
- Organizer
  日本ハイパーサーミア学会第22回大会
- Place of Presentation
  岡山
- Year and Date
  2005-09-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] NBS1標的siRNAによるNF-κB細胞生存シグナル伝達系阻害2005
- Author(s)
  大西健, et. al.
- Organizer
  第44回日本医学放射線学会生物部会学術大会
- Place of Presentation
  東京
- Year and Date
  2005-07-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] New aspect of fundamental study in hyperthermia2005
- Author(s)
  Ohnishi, T
- Organizer
  The 22nd Annual Meeting of The Japanese Society of Hyperthermic Oncology
- Place of Presentation
  Okayama
- Year and Date
  2005-09-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線によるがん治療を科学ずる-細胞死のメカニズムー2005
- Author(s)
  Ohnishi, T
- Organizer
  放射線腫瘍学夏季セミナー
- Place of Presentation
  Nara
- Year and Date
  2005-08-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] ハイパーサーミア基礎研究の新展開-細胞の温熱応答と耐性機構2005
- Author(s)
  大西武雄, et. al.
- Organizer
  日本ハイパーサーミア学会第22回大会
- Place of Presentation
  岡山
- Year and Date
  2005-09-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽放射粒子と生命とのかかわり合い2005
- Author(s)
  Ohnishi, T
- Organizer
  岐阜市民公開シンポジウム
- Place of Presentation
  Gifu
- Year and Date
  2005-01-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線によるがん治療を科学する-細胞死のメカニズム2005
- Author(s)
  大西武雄
- Organizer
  放射線腫瘍学夏季セミナー
- Place of Presentation
  奈良
- Year and Date
  2005-08-05
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線生物学の役割と発展-癌研究から宇宙研究へ2005
- Author(s)
  大西武雄
- Organizer
  医学生、研究生のための放射線治療セミナー, 特別講演
- Place of Presentation
  奈良
- Year and Date
  2005-08-07
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] NBS1標的siRNAによる肺癌細胞の放射線増感メカニズムの検討2005
- Author(s)
  大西健, et. al.
- Organizer
  第64回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2005-09-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] DNA修復因子を標的としたsiRNAによるヒト癌細胞の放射線/温熱増感2005
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  7th Symposium on Sensitization of Cancer Treatment in Nara
- Place of Presentation
  Nara
- Year and Date
  2005-02-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線適応応答-放射線治療からの局面から2005
- Author(s)
  大西武雄
- Organizer
  桜山イメージングセミナー
- Place of Presentation
  名古屋
- Year and Date
  2005-11-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線影響研究への期待2005
- Author(s)
  Ohnishi, T
- Organizer
  若手放射線生物学研究会, 特別講演
- Place of Presentation
  Osaka
- Year and Date
  2005-08-26
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽・地球・生命-宇宙実験から知りえたもの2005
- Author(s)
  Ohnishi, T
- Organizer
  第42回日本公衆衛生学会近畿地方会
- Place of Presentation
  Nara
- Year and Date
  2005-05-20
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] NBS1の放射線誘導NF-κB細胞生存シグナル伝達系への関与2005
- Author(s)
  大西健, et. al.
- Organizer
  日本放射線影響学会第48回大会
- Place of Presentation
  広島
- Year and Date
  2005-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] p53遺伝子型からみたHSP合成阻害剤による温熱倣射線増感2005
- Author(s)
  大西健, et. al.
- Organizer
  日本ハイパーサーミア学会第22回大会
- Place of Presentation
  岡山
- Year and Date
  2005-09-23
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線生物学の役割と発展-癌研究から宇宙研究へ2005
- Author(s)
  Ohnishi, T
- Organizer
  医学生研究生のための放射線治療セミナー, 特別講演
- Place of Presentation
  Nara
- Year and Date
  2005-08-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Mediation of NBS1 to radiation-induced cellular survival signaling pathway via NF -kB2005
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 48th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Hiroshima
- Year and Date
  2005-11-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線影響研究への期待2005
- Author(s)
  大西武雄
- Organizer
  若手放射線生物学研究会, 特別講演
- Place of Presentation
  大阪
- Year and Date
  2005-08-26
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] p53-dependent enhancement of radiosensitivity by heat in huniin cancer cells2005
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  The 22nd Annual Meeting of The Japanese Society of Hyperthermic Oncology
- Place of Presentation
  Okayama
- Year and Date
  2005-09-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] ハイパーサーミア治療ー今注目される研究とは2005
- Author(s)
  Ohnishi, T
- Organizer
  全身ハイパーサーミア研究会公開シンポジゥム
- Place of Presentation
  Tokyo
- Year and Date
  2005-01-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] NBS1を標的としたsiRNAによる放射線増感2005
- Author(s)
  大西健, et. al.
- Organizer
  第35回放射線による制癌シンポジウム
- Place of Presentation
  東京
- Year and Date
  2005-07-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 太陽、地球、生命-宇宙実験から知りえたもの2005
- Author(s)
  大西武雄
- Organizer
  第42回日本公衆衛生学会近畿地方会
- Place of Presentation
  奈良
- Year and Date
  2005-05-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] The DSB-recognizing proteins phospho-Nbs1 and Mrel1 co-localize with γH2AX in the cell nucleus after heat treatment as well as X-ray irradiation2005
- Author(s)
  Ohnishi T., et. al.
- Organizer
  52nd Annual Meeting of the Radiation Research Society
- Place of Presentation
  Denver,USA
- Year and Date
  2005-10-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 放射線適応応答-放射線治療からの局面から-2005
- Author(s)
  Ohnishi, T
- Organizer
  桜山イメージングセミナー
- Place of Presentation
  Nagoya
- Year and Date
  2005-11-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Heat/radiation sensitization by HSP inhibitors from an aspect of p53 gene status2005
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  The 22nd Annual Meeting of The Japanese Society of Hyperthermic Oncology
- Place of Presentation
  Okayama
- Year and Date
  2005-09-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] NBS1標的siRNAによるNF-kB細胞生存シグナル伝達系阻害2005
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第44回日本医学放射線学会生物部会学術大会
- Place of Presentation
  Tokyo
- Year and Date
  2005-07-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Mechanism of radiation sensitization by siRNA-targeted for NBS1 in human lung cancer cells2005
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  64th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Sapporo
- Year and Date
  2005-09-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] 陽、地球、生命-宇宙実験から知りえたもの2005
- Author(s)
  大西武雄
- Organizer
  日本防菌防黴学会第32回年次大会, 招待講演
- Place of Presentation
  大阪
- Year and Date
  2005-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Possibility of synergism on biological effects of space radiations under microgravity environment2005
- Author(s)
  Ohnishi T., et. al.
- Organizer
  日本放射線影響学会第48回大会
- Place of Presentation
  広島
- Year and Date
  2005-11-15
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] Possibility of synergism on biological effects of space radiations under microgravity environment2005
- Author(s)
  Ohnishi, T., et. al.
- Organizer
  The 48th Annual Meeting of the Japanese Radiation Research Society
- Place of Presentation
  Hiroshima
- Year and Date
  2005-11-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] NBS1を標的としたsiRNAによる放射線増感2005
- Author(s)
  Ohnishi, K., et. al.
- Organizer
  第35回放射線による制癌シンポジウム
- Place of Presentation
  Tokyo
- Year and Date
  2005-07-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17201015
[Presentation] グリオブラストーマスフェロイドの低酸素微小環境に出現するCD133陽性細胞は放射線及びCDDP抵抗性を示す
- Author(s)
  大西健、他
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-26670461
[Presentation] 神経膠芽腫スフェロイドの低酸素領域に出現するCD133陽性細胞は放射線/抗がん剤抵抗性を示す
- Author(s)
  大西健、他
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-26670461

1. HATANO Osamu (40164850)

# of Collaborated Projects: 6 results

# of Collaborated Products: 36 results
2. OHNISHI Takeo (60094554)

# of Collaborated Projects: 4 results

# of Collaborated Products: 243 results
3. TAKEMORI Hiroshi (90273672)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
4. TAKAHASHI Akihisa (60275336)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 竹田浩之 (40609393)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. NISHI Mayumi (40295639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. NONAKA Yasuki (80156215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. OHTA Miho (90132935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. NOBUO Kubota (20046139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
10. FUJII Yoshihro (20637540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Shimamoto Naoto (80295435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KATAGIRI Masanao (00185802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MATSUO Jiro (40263123)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. ISOZAKI Katsuhiro (30455274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. IWASAKI Tetsusi (40379483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松本英樹 (40142377)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 矢尾育子 (60399681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 三宅牧人 (80601400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. IWASAKI Tetsushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 原田浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 片桐昌直

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

OHNISHI Ken 大西 健

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がん幹細胞を標的としたより治療効果の高いホウ素中性子捕捉療法の基礎研究Principal Investigator

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Establishment of a cancer stem cell line for radiation biological researchPrincipal Investigator

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Screening of radio-sensitizing phytochemicals and examination on their structuresPrincipal Investigator

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Study on the radiation/heat/anti-cancer drag sensitivity enhanced by siRNA in mutated-p53 cancer cellsPrincipal Investigator

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Study on twnor growth inhibition by small interference RNAin nude micePrincipal Investigator

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OHNISHI Ken 大西健