Nishimura Hidekazu 西村秀一

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NISHIMURA Hidekazu 西村秀一

西村秀和ニシムラヒデカズ

西村秀ニシムラヒデカズ

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Researcher Number	50172698
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Affiliation (Current)	2022: 独立行政法人国立病院機構(仙台医療センター臨床研究部), その他部局等, 医長・室長
Affiliation (based on the past Project Information) *help	2017 – 2021: 独立行政法人国立病院機構(仙台医療センター臨床研究部), その他部局等, 医長・室長 2016: 独立行政法人国立病院機構(仙台医療センター臨床研究部), ウイルス疾病研究室, ウイルス疾病研究室長 2015: 独立行政法人国立病院機構(仙台医療センター), その他部局等, ウイルス疾患研究室長 2015: 独立行政法人国立病院機構仙台医療センター臨床研究部, 臨床研究部ウイルスセンター, 臨床研究部ウイルスセンター長 2012 – 2015: 独立行政法人国立病院機構(仙台医療センター臨床研究部), 臨床研究部ウイルスセンター, 臨床研究部ウイルスセンター長 … More 2014: 独立行政法人国立病院機構(仙台医療センター臨床研究部), その他部局等, ウイルス疾患研究室長 2012 – 2013: 独立行政法人国立病院機構(仙台医療センター臨床研究部), 病因研究室, 病因研究室長 2012: 独立行政法人国立病院機構仙台医療センター臨床研究部, 臨床研究部ウイルスセンター, 臨床研究部ウイルスセンター長 2011: 仙台医療センター, 臨床研究部, 室長 2010: 独立行政法人国立病院機構(仙台医療センター臨床研究部), 室長 2010: 独立行政法人国立病院機構仙台医療センター, 臨床研究部, 病因研究室長 2009: 仙台医療センター, 臨床研究部, 室長 1988 – 1992: 山形大学, 医学部, 助手 1986: Yamagata University School of Medicine Assistant, 医学部, 助手 Less
Review Section/Research Field	Except Principal Investigator Virology / Pediatrics / Respiratory organ internal medicine / Infectious disease medicine / Community health nursing / Basic Section 53030:Respiratory medicine-related
Keywords	Except Principal Investigator C型インフルエンザウイルス / Influenza C virus / 糖蛋白質 / 抗原変異 / 小児感染症学 / 感染症 / インフルエンザ / 気道上皮細胞 / 単クロ-ン抗体 / Glycoprotein … More / HE蛋白 / ヘムアグルチニン・エステラ-ゼ / 抗原変異株 / HE protein / antigenic variation / モノクローナル抗体 / ヘムアグルチニン・エステラーゼ / レセプター認識部位 / 馴化 / RSV / 臨床分離株 / マウスモデル / 遺伝子解析 / 統計樹解析 / Th1 / Th2 / マウス / 動物実験 / 気道粘液 / 気道抵抗 / ウイルス / 臨床 / 検査 / 重症化阻止 / インフルエンザウイルス / ウイルス増殖 / 温度環境 / 病原性 / 感染症診断学 / 肺炎 / リアルタイムPCR / 災害対策 / 危機管理 / 保育園 / 幼稚園 / 自然災害 / 方法論 / 災害弱者 / 津波 / 避難 / 感染制御 / 地域 / モデル / 防災 / 地震津波対策 / 地域支援 / 防災教育 / コミュニティケア / インフルエンザ流行 / 小学校 / 津波災害 / 地域対策 / 赤血球凝集活性 / レセプタ-破壊活性 / セリンエステラ-ゼ / 赤血球擬集活性 / Hemagglutinability / Receptor destroying activity / Serine esterase / Monoclonal antibody / 抗原構造 / 抗原地図 / 中和エピト-プ / antigenic structure / monoclonal antibody / 培養細胞への馴化 / 抗原変異株の選択 / ヘムアグルチニン・エステラ-ゼ蛋白 / 宿主による選択 / adaptation to cultivated cells / 抗原性 / 糖鎖 / Influenza C Virus / Carbohydratos / Immunogenicity / 分子疫学 / ヘムアグルチニン-エステラ-ゼ / HE遺伝子の塩基配列 / HE蛋白のアミノ酸配列 / Antigenic variation / Molecular epidemiology / hemagglutinin-esterase / C型ライノウイルス / ウイルス放出量定量化 / マクロライド / 炎症性サイトカイン / PCR法 / 気管支喘息 / 慢性閉塞性肺疾患 / 鼻腔上皮細胞 / 気管上皮細胞 Less

Development of methods to quantify the release of type C rhinovirus from airway epithelial cells obtained from patients with obstructive pulmonary diseases
- Principal Investigator
  
  Yamaya Mutsuo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Tohoku University
Influenza epidemic control research based on elementary school and construction of application model for disaster countermeasures
- Principal Investigator
  
  SHIMIZU NOBUAKI
- Project Period (FY)
  2014 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Community health nursing
- Research Institution
  Aichi Prefectural University
Development of rapid diagnostic system for causative organisms of pneumonia and drug resistance using real-time PCR and its application to primary care settings
- Principal Investigator
  
  KUBO Toru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Nagasaki University
Development of methods to define the pathogenic magnitude of the influenza virus infection using human airway epithelial cells
- Principal Investigator
  
  YAMAYA Mutsuo
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Developing a panel of reverse-transcription loop-mediated isothermal amplification (RT-LAMP) assays for comprehensive detection of causing viruses in pediatric severe pneumonia
- Principal Investigator
  
  KUBO Toru
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Nagasaki University
Elucidation of new mechanisms of RSV infection by clinical isolate analysis using a mouse model
- Principal Investigator
  
  HASHIMOTO Koichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Fukushima Medical University
C型インフルエンザウイルスのレセプター認識と出芽機構に関する研究
- Principal Investigator
  
  NAKAMURA Kiyoto
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yamagata University
Molecular epidemiology of type C influenza
- Principal Investigator
  
  NAKAMURA Kiyoto
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Yamagata University
Host cell-mediated selection of influenza C variants
- Principal Investigator
  
  SUGAWARA Kanetsu
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Yamagata University
Receptor Recognition Site in Hemagglutinin-Esterase Glycoprotein of Influenza C Virus
- Principal Investigator
  
  KITAME Fumio
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Virology
- Research Institution
  Yamagata University
Studies on the significance of antigenic variation in influenza C epidemiology
- Principal Investigator
  
  NAKAMURA Kiyoto
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Yamagata University
The role of glycosylation in determining the immunogenicity of influenza C virus glycoprotein
- Principal Investigator
  
  NAKAMURA Kiyoto
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Yamagata University

All 2021 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] The proton ATPase inhibitor bafilomycin A1 reduces the release of rhinovirus C and cytokines from primary cultures of human nasal epithelial cells.2021
- Author(s)
  Yamaya M, Deng X, Kikuchi A, Sugawara M, Sato N, Kubo T, Momma H, Kawase T, Nakagome K, Shimotai Y, Nishimura H.
- Journal Title
  
  Virus Res
  
  Volume: 304 Pages: 198548-198548
- DOI
  10.1016/j.virusres.2021.198548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08620, KAKENHI-PROJECT-18K08153, KAKENHI-PROJECT-21K08186
[Journal Article] Effects of neuraminidase inhibitors on the release of oseltamivir-sensitive and oseltamivir-resistant influenza viruses from human airway epithelial cells2014
- Author(s)
  Yamaya M, Nishimura H, Kubo H, Nagatomi R.
- Journal Title
  
  J Med Virol
  
  Volume: (in press, (ISSN)1096-9071)
- URL
  http://onlinelibrary.wiley.com/journal/10.1002/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659398
[Journal Article] Formoterol and budesonide inhibit rhinovirus infection and cytokine production in primary cultures of human tracheal epithelial cells2014
- Author(s)
  Yamaya M, Nishimura H, Nadine L, Kubo H, Nagatomi R.
- Journal Title
  
  Respir Invest
  
  Volume: (in press)
- DOI
  10.1016/j.resinv.2014.03.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659398
[Journal Article] Tulobuterol inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells2013
- Author(s)
  Yamaya M, Nishimura H, Nadine L, Kubo H, Nagatomi R.
- Journal Title
  
  Physiol Reports
  
  Volume: 1
- DOI
  10.1002/phy2.41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659398
[Journal Article] Levofloxacin inhibits rhinovirus infection in primary cultures of human tracheal epithelial cells2012
- Author(s)
  Yamaya M, Nishimura H, Hatachi Y, Yasuda H, Deng X, Sasaki T, Mizuta K, Kubo H, and Nagatomi R.
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 56 Pages: 4052-4061
- DOI
  10.1128/aac.00259-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390163, KAKENHI-PROJECT-24659398
[Journal Article] Inhibitory effects of tiotropium on rhinovirus infection in human airway epithelial cells2012
- Author(s)
  Yamaya M, Nishimura H, Hatachi Y, Yasuda H, Deng X, Sasaki T, Kubo H, Nagatomi R.
- Journal Title
  
  Eur Respir J
  
  Volume: 40 Pages: 122-132
- DOI
  10.1183/09031936.00065111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659398
[Presentation] Serine protease inhibitors suppress influenza virus infection in human airway epithelial cells2013
- Author(s)
  Yamaya M, Hatachi Y, Kubo H, Nadine LK, Nishimura H.
- Organizer
  (Poster presentation) American Thoracic Society International Conference
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-24659398
[Presentation] エンテロウイルス71に対するRT-LAMP法を用いた迅速診断系の開発とその臨床応用に関する研究2012
- Author(s)
  久保　亨、吾郷　昌信、森内　浩幸、西村　秀一、森田　公一（久保　亨）
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  グランキューブ大阪（大阪府）
- Data Source
  KAKENHI-PROJECT-22591186
[Presentation] Clarithromycin inhibits pandemic A/H1N1/2009 influenza virus infection in human airway epithelial cells2012
- Author(s)
  Yamaya M, Hatachi Y, Kubo H, Nishimura H.
- Organizer
  (P4364、Session 448) (Poster discussion) European Respiratory Society Annual Congress
- Place of Presentation
  Vienna, Austria
- Year and Date
  2012-09-04
- Data Source
  KAKENHI-PROJECT-24659398
[Presentation] L-Carbocisteine inhibits respiratory syncytial virus infection in human airway epithelial cells2012
- Author(s)
  Yamaya M, Hatachi Y, Kubo H, Nishimura H.
- Organizer
  (Poster presentation) American Thoracic Society 2012 International Conference
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24659398
[Presentation] Formoterol and budesonide inhibits rhinovirus infection in human airway epithelial cells2012
- Author(s)
  Yamaya M, Hatachi Y, Kubo H, Nishimura H.
- Organizer
  (Poster presentation) American Thoracic Society 2012 International Conference
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24659398
[Presentation] エンテロウイルス71に対するRT-LAMP法を用いた迅速診断系の開発とその臨床応用に関する研究2012
- Author(s)
  久保亨、吾郷昌信、森内浩幸、西村秀一、森田公一
- Organizer
  第60回日本ウイルス学会学術集会
- Place of Presentation
  グランキューブ大阪(大阪府)
- Year and Date
  2012-11-14
- Data Source
  KAKENHI-PROJECT-22591186
[Presentation] Tulobuterol inhibits rhinovirus infection in human airway epithelia cells2012
- Author(s)
  Yamaya M, Y. Hatachi Y, Kubo H, Nishimura H.
- Organizer
  (Poster presentation) American Thoracic Society 2012 International Conference
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24659398
[Presentation] 新型および季節性インフルエンザ迅速鑑別診断のためのRT-LAMP法パネルの開発と、その臨床応用について2011
- Author(s)
  久保亨、福島喜代康、西村秀一、河野茂、森田公一
- Organizer
  第85回日本感染症学会総会学術講演会
- Place of Presentation
  ザプリンスパークタワー東京(東京都)
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-22591186
[Presentation] Developing a panel of reverse-transcription loop-mediated isothermal amplification (RT-LAMP) assays for comprehensive detection of causing viruses in pediatric severe pneumonia2011
- Author(s)
  Toru Kubo, Hidekazu Nishimura, Hiroyuki Moriuchi, Kouichi Morita
- Organizer
  XV International Congress of Virology
- Place of Presentation
  札幌コンベンションセンター(北海道)
- Year and Date
  2011-09-13
- Data Source
  KAKENHI-PROJECT-22591186
[Presentation] 新型および季節性インフルエンザの迅速鑑別診断のためのRT-LAMP法パネルの開発と、その臨床応用の研究2010
- Author(s)
  保亨、L. Q. Mai、吾郷昌信、福島喜代康、西村秀一、吉川亮、山口顕徳、平野学、井手昇太郎、河野茂、長谷部太、森田公一
- Organizer
  第58回日本ウイルス学会学術集会
- Place of Presentation
  徳島県徳島市あわぎんホール(徳島県)
- Year and Date
  2010-11-08
- Data Source
  KAKENHI-PROJECT-22591186
[Presentation] 新型インフルエンザウイルス特異的RTLAMP法の開発と、その臨床応用の研究2010
- Author(s)
  久保亨、福島喜代康、西村秀一、井手昇太郎、河野茂、森田公一
- Organizer
  第84回日本感染症学会総会学術講演会
- Place of Presentation
  京都府京都市国立京都国際会館(京都府)
- Year and Date
  2010-04-06
- Data Source
  KAKENHI-PROJECT-22591186

1. SUGAWARA Kanetsu (60110673)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. KITAME Fumio (40004676)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. NAKAMURA Kiyoto (00125775)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. KUBO Toru (50444873)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. MORIUCHI Hiroyuki (90315234)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. YAMAYA Mutsuo (60261640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
7. HASHIMOTO Koichi (50322342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HASHIMOTO Yuko (60305357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HOSOYA Mistuaki (80192318)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. SUZUTANI Tastuo (40196895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAWASAKI Yukihiko (00305369)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MORITA Kouichi (40182240)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. SHIMIZU NOBUAKI (70261831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. TAKIGUCHI Kazuhiko (20143125)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 本郷誠治 (90229245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 脇坂浩 (80365189)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAKAGOME Kazuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 久保裕司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishimura Hidekazu 西村 秀一

NISHIMURA Hidekazu 西村 秀一

西村 秀和 ニシムラ ヒデカズ

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[Journal Article] The proton ATPase inhibitor bafilomycin A1 reduces the release of rhinovirus C and cytokines from primary cultures of human nasal epithelial cells.2021

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[Journal Article] Effects of neuraminidase inhibitors on the release of oseltamivir-sensitive and oseltamivir-resistant influenza viruses from human airway epithelial cells2014

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[Journal Article] Formoterol and budesonide inhibit rhinovirus infection and cytokine production in primary cultures of human tracheal epithelial cells2014

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Nishimura Hidekazu 西村秀一

NISHIMURA Hidekazu 西村秀一

西村秀和ニシムラヒデカズ

西村秀ニシムラヒデカズ