Kodama Eiichi 児玉栄一

… Alternative Names

Researcher Number	50271151
Other IDs
Affiliation (Current)	2019: 東北大学, 災害科学国際研究所, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 東北大学, 災害科学国際研究所, 教授 2012 – 2015: 東北大学, 医学(系)研究科(研究院), 講師 2013: 東北大学, 大学院医学系研究科, 講師 2012: 東北大学, 東北メディカル・メガバンク機構, 講師 2009 – 2011: Tohoku University, 病院, 助教 2003 – 2006: 京都大学, ウイルス研究所, 助手 2000 – 2001: 京都大学, ウイルス研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / 膠原病・アレルギー・感染症内科学 / Applied pharmacology / Infectious disease medicine / 内科学一般 / Basic Section 54030:Infectious disease medicine-related Except Principal Investigator Hematology / Applied pharmacology / Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords	Principal Investigator HIV / 薬剤耐性 / 逆転写酵素 / ヒト免疫不全症ウイルス / ウイルス / 核酸 / 治療 / ペプチド / 耐性 / ＨＩＶ … More Except Principal Investigator ヘルペスウイルス / リン酸化 / 抗ウイルス剤 / DNAメチル化 / デングウイルス / デング熱 / デング出血熱 / ガレクチンー９ / オステオポンチン / バイオマーカー / ガレクチン / プロモーター / ウイルス / ＨＩＶ / 薬剤耐性 / 逆転写酵素 / 多剤耐性 / HIV / エクソソーム / 細胞分泌小胞 / 細胞治療 / 細胞内包ゲル Less

ストレス応答生合成と化学修飾を融合した多様性天然物による難治性疾患治療薬の開発Principal InvestigatorOngoing
- Principal Investigator
  
  児玉栄一
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Tohoku University
細胞治療を指向した機能性エクソソーム分泌細胞内包ゲルの開発Ongoing
- Principal Investigator
  
  中瀬生彦
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Osaka Prefecture University
Novel screenings for unmet medical needs with innovative new natural product derived compoundsPrincipal Investigator
- Principal Investigator
  
  児玉栄一
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tohoku University
Development of antiviral agents targeting ATP-mediated excisionPrincipal Investigator
- Principal Investigator
  
  Kodama Eiichi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Development of anti-HIV agents that exert synergism with host immune pressurePrincipal Investigator
- Principal Investigator
  
  KODAMA Eiichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Tohoku University
Clinical Utilities of new biomarker for dengue virus infection
- Principal Investigator
  
  HATTORI Toshio
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  Tohoku University
Mechanism of resistance to translocation defective reverse transcriptase inhibitors
- Principal Investigator
  
  ASHINO Yugo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Effect of a novel resistance associated mutation, N348I, which has been identified in Japanese HIV-1 infected patients, on the reverse transcriptase activity.Principal Investigator
- Principal Investigator
  
  KODAMA Eiichi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Tohoku University
Establishment of Rev based anti-HIV therapy.Principal Investigator
- Principal Investigator
  
  KODAMA Eiichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyoto University
ヘルペスウイルスを標的とした新規治療薬開発による難治性腫瘍克服
- Principal Investigator
  
  松岡雅雄
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
ヒト免疫不全症ウイルス・細胞融合機構の解明と治療への応用Principal Investigator
- Principal Investigator
  
  児玉栄一
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  Kyoto University
新規HIV複製ステップの同定及びその阻害剤開発への応用Principal Investigator
- Principal Investigator
  
  児玉栄一
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
新規HIV複製ステップの同定及びその阻害剤開発への応用Principal Investigator
- Principal Investigator
  
  児玉栄一
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
薬剤耐性HIVに著効を示す新規核酸誘導体の開発Principal Investigator
- Principal Investigator
  
  児玉栄一
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Kyoto University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation

[Journal Article] Construction of a Meroterpenoid-like Compounds Library Based onDiversity-Enhanced Extracts2019
- Author(s)
  Kikuchi Haruhisa、Kawai Kosuke、Nakashiro Yota、Yonezawa Takayuki、Kawaji Kumi、Kodama Eiichi. N.、Oshima Yoshiteru
- Journal Title
  
  Chemistry - A European Journal
  
  Volume: 25 Pages: 1106-1112
- DOI
  10.1002/chem.201805417
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H03279, KAKENHI-PROJECT-16H05346
[Journal Article] Identification of human immunodeficiency virus type-1 Gag-TSG101interaction inhibitors by high-throughput screening.2018
- Author(s)
  Lowela Siarot, Nopporn Chutiwitoonchai, Hirotaka Sato, Hao Chang, Hironori Sato, Masayuki,Fujino,Tsutomu Murakami,Toshihiro Aono, Eiichi Kodama, Kazumichi Kuroda, Masami Takei, Yoko Aida
- Journal Title
  
  Biochemical and Biophysical Research Communications.
  
  Volume: 503 Pages: 2970-2976
- DOI
  10.1016/j.bbrc.2018.08.079
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02590, KAKENHI-PROJECT-16H05346, KAKENHI-PROJECT-18H03046, KAKENHI-PROJECT-15K10043
[Journal Article] A Cinnamon-Derived Procyanidin.Compound Displays Anti-HIV-1 Activity by Blocking Heparan Sulfate- and Co-Receptor- Binding Sites on gp120 and Reverses T Cell Exhaustion via Impeding Tim-3 and PD-1 Upregulation2016
- Author(s)
  Connell BJ, Chang SY, Prakash E, Yousfi R, Mohan V, Posch W, Wilflingseder D, Moog C, Kodama EN, Clayette P, Lortat-Jacob H.
- Journal Title
  
  PLoS One.
  
  Volume: 2
- DOI
  10.1371/journal.pone.0165386
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05346
[Journal Article] A Novel Peptide Derived from the Fusion Protein Heptad Repeat Inhibits Replication of Subacute Sclerosing Panencephalitis Virus In Vitro and In Vivo2016
- Author(s)
  Watanabe M, Hashimoto K, Abe Y, Kodama EN, Nabika R, Oishi S, Ohara S, Sato M,Kawasaki Y, Fujii N, Hosoya M.
- Journal Title
  
  PLOS ONE
  
  Volume: 11
- DOI
  10.1371/journal.pone.0162823
- NAID
  120005997738
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05346, KAKENHI-PROJECT-15H04654
[Journal Article] Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA).2016
- Author(s)
  Salie ZL, Kirby KA, Michailidis E, Marchand B, Singh K, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 113 Pages: 9274-9
- DOI
  10.1073/pnas.1605223113
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05346, KAKENHI-PROJECT-26293239, KAKENHI-PROJECT-16K15520
[Journal Article] Inhibition of the DNA　polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1　replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki)　components2015
- Author(s)
  Tetsuro Hisayoshi, Mayu Shinomura, Kanta Yokokawa, Ikumi Kuze, Atsushi Konishi, Kumi Kawaji, Eiichi N. Kodama, Keishi Hata, Saori Takahashi, Satoru Nirasawa, Kiyoshi Yasukawa.
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: in press Pages: 432-440
- DOI
  10.1007/s11418-015-0885-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25670255
[Journal Article] Synthesis of a Vpr-Binding Derivative forUse as a Novel HIV-1 Inhibitor.2015
- Author(s)
  Hagiwara K, Ishii H, Murakami T, Takeshima SN, Chutiwitoonchai N, Kodama EN, Kawaji K, Kondoh Y, Honda K, Osada H, Tsunetsugu-Yokota Y, Suzuki M, Aida Y
- Journal Title
  
  PLoS One
  
  Volume: 10
- DOI
  10.1371/journal.pone.0145573
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26350976, KAKENHI-PROJECT-25670255
[Journal Article] Anti-HIV-1 activitydetermined byb-galactosidase activityin the multinuclear activation ofan indicator assay is comparable with that by a conventional focus counting method.2015
- Author(s)
  Fusako Miyamoto, Kumi Kawaji, Shinya Oishi, Nobutaka Fujii, Mitsuo Kaku, and Eiichi N.Kodama.
- Journal Title
  
  Antiviral Chemistry and Chemotherapy
  
  Volume: 24（2） Pages: 77-82
- DOI
  10.1177/2040206615614164
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25670255
[Journal Article] Use of a biosynthetic intermediate to explore the chemical diversity of pseudo-natural fungal polyketides2015
- Author(s)
  T. Asai*, K. Tsukada, S. Ise, N. Shirata, M. Hashimoto, I. Fujii, K. Gomi, K. Nakagawara, E. N. Kodama, Y, Oshima
- Journal Title
  
  Nature Chemistry
  
  Volume: 7 Pages: 737-743
- DOI
  10.1038/nchem.2308
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460117, KAKENHI-PROJECT-25670255, KAKENHI-PROJECT-25293022
[Journal Article] Histone chaperone CAF-1 mediatesrepressive histone modifications to protect preimplantation mouse embryos from endogenousretrotransposons.2015
- Author(s)
  Hatanaka Y, Inoue K, Oikawa M, Kamimura S, Ogonuki N, Kodam E, Ohkawa Y, Tsukada Y, Ogura A.
- Journal Title
  
  Proceedings of the National Academy of Sciences U.S.A
  
  Volume: 112 Pages: 14641-14646
- DOI
  10.1073/pnas.1512775112
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26430100, KAKENHI-PROJECT-15K18545, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112008, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25670255, KAKENHI-PROJECT-26290064
[Journal Article] Delayed emergence of HIV-1 variants resistant to 4′-ethynyl-2-fluoro-2′-deoxyadeno -sine: comparative sequential passage study with lamivudine, tenofovir, emtricitabine and BMS-9860012014
- Author(s)
  Kenji Maeda, Darshan V Desai, Manabu Aoki, Hirotomo Nakata, Eiichi N Kodama, Hiroaki Mitsuya
- Journal Title
  
  Antivir Ther
  
  Volume: 19 Pages: 179-189
- DOI
  10.3851/imp2697
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-24791031, KAKENHI-PROJECT-25670255, KAKENHI-PROJECT-26461510
[Journal Article] 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) inhibits HIV-12014
- Author(s)
  Eleftherios Michailidis, Andrew D. Huber, Emily M. Ryan, Yee T. Ong,　Maxwell D. Leslie, Kayla B. Matzek, Kamalendra Singh, Bruno Marchand, Ariel N. Hagedorn, Karen A. Kirby, Lisa C. Rohan, Eiichi N. Kodama, Hiroaki Mitsuya, Michael A. Parniak, and Stefan G. Sarafianos.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Pages: 24533-24548
- DOI
  10.1074/jbc.m114.562694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25670255
[Journal Article] Current research on chronic active Epstein-Barr virus infection in　Japan2014
- Author(s)
  Fujiwara S, Kimura H, Imadome K, Arai A, Kodama, E, Morio T, Shimizu N, and Wakiguchi H.
- Journal Title
  
  Pediatr Int
  
  Volume: 56 Pages: 159-166
- DOI
  10.1111/ped.12314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591375, KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-24659493, KAKENHI-PROJECT-25293109, KAKENHI-PROJECT-25670255
[Journal Article] Evaluation of combinations of 4'-ethynyl-2-fluoro-2'-deoxyadenosine with clinically used antiretroviral drugs.2013
- Author(s)
  Atsuko Hachiya, Aaron Reeve, Bruno Marchand, Eleftherios Michailidis, Yee Ong, Karen Kirby, Maxwell Leslie, Shinichi Oka, Eiichi Kodama, Lisa Rohan, Hiroaki Mitsuya, Michael Parniak, and Stefan Sarafianos
- Journal Title
  
  Antimicrobal Agents and Chemotherapy
  
  Volume: 57 Pages: 4554-4558
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] HIV-1 resistance mechanism to an electrostatically constrained peptide fusion inhibitor that is active against T-20-resistant strains2013
- Author(s)
  Kazuki Shimane, KumiKawaji, Fusako Miyamoto, Shinya Oishi, Kentaro Watanabe, YasukoSakagami, Nobutaka Fujii, Kazuya Shimura, Masao Matsuoka, Mitsuo Kaku, Stefan Sarafianos, and Eiichi Kodama
- Journal Title
  
  Antimicrobal Agents and Chemotherapy
  
  Volume: 57 Pages: 4035-4038
- Data Source
  KAKENHI-PROJECT-25670255
[Journal Article] Mechanism of Resistance to S138A Substituted Enfuvirtide and its Application to Peptide Design2013
- Author(s)
  Kazuki Izumi, Kumi Kawaji, Fusasko Miyamoto, Kazuki Shimane, Kazuya Shimura, Yasuko Sakagami, Toshio Hattori, Kentaro Watanabe, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka, Mitsuo Kaku, Stefan G. Sarafianos, and Eiichi N. Kodama
- Journal Title
  
  International Journal of Biochemistry and Cell Biology
  
  Volume: 45 Pages: 908-915
- Data Source
  KAKENHI-PROJECT-25670255
[Journal Article] Development of small molecule HIV-1 fusion inhibitors: linking Biology to Chemistry. Current Pharmaceutical Design2013
- Author(s)
  Fusako Miyamoto and Eiichi N Kodama
- Journal Title
  
  Current Pharmaceutical Design
  
  Volume: 19 Pages: 1827-1834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Hypersusceptibility Mechanism of Tenofovir-Resistant HIV to EFdA2013
- Author(s)
  Eleftherios Michailidis, Emily M Ryan, Atsuko Hachiya, Karen A Kirby, Bruno Marchand, Maxwell D Leslie, Andrew D Huber, Yee T Ong, Jacob C Jackson, Kamalendra Singh, Eiichi N Kodama, Hiroaki Mitsuya, Michael A Parniak and Stefan G Sarafianos
- Journal Title
  
  Retrovirology
  
  Volume: 10 Pages: 65-65
- DOI
  10.1186/1742-4690-10-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-25670255
[Journal Article] Evaluation of combinations of 4'-ethynyl-2-fluoro-2'-deoxyadenosine with clinically used antiretroviral drugs2013
- Author(s)
  Atsuko Hachiya, Aaron Reeve, Bruno Marchand, Eleftherios Michailidis, Yee Ong, Karen Kirby, Maxwell Leslie, Shinichi Oka, Eiichi Kodama, Lisa Rohan, Hiroaki Mitsuya, Michael Parniak, and Stefan Sarafianos
- Journal Title
  
  Antimicrobal Agents and Chemotherapy
  
  Volume: 57 Pages: 4554-4558
- Data Source
  KAKENHI-PROJECT-25670255
[Journal Article] Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design2013
- Author(s)
  Izumi K, Kawaji K, Miyamoto F, Shimane K, Shimura K, Sakagami Y, Hattori T, Watanabe K, Oishi S, Fujii N, Matsuoka M, Kaku M, Sarafianos SG, Kodama EN.
- Journal Title
  
  Int J Biochem Cell Biol
  
  Volume: 45 Pages: 908-15
- DOI
  10.1016/j.biocel.2013.01.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636, KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-24791021
[Journal Article] Mechanism of resistance to S138A substituted enfuvirtide and its application to peptide design.2013
- Author(s)
  Kazuki Izumi, Kumi Kawaji, Fusasko Miyamoto, Kazuki Shimane, Kazuya Shimura, Yasuko Sakagami, Toshio Hattori, Kentaro Watanabe, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka, Mitsuo Kaku, Stefan G. Sarafianos, and Eiichi N. Kodama
- Journal Title
  
  Int. J. Biovjem. Cell Biol.
  
  Volume: 45 Pages: 908-915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] 新しい抗ウイルス剤開発の考え方2013
- Author(s)
  児玉栄一、宮本総子
- Journal Title
  
  臨床と微生物
  
  Volume: 40 Pages: 51-55
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Sarafianos SG.Effects of substitutions at the 4' and 2 positions on the bioactivity of 4'-ethynyl-2-fluoro-2'-deoxyadenosine2013
- Author(s)
  Kirby KA, Michailidis E, Fetterly TL, Steinbach MA, Singh K, Marchand B, Leslie MD, Hagedorn AN, Kodama EN, Marquez VE, Hughes SH, Mitsuya H, Parniak MA
- Journal Title
  
  Antimicrobal Agents and Chemotherapy
  
  Volume: 57 Pages: 6254-6264
- Data Source
  KAKENHI-PROJECT-25670255
[Journal Article] Development of Small Molecule HIV-1 Fusion Inhibitors: Linking Biology to Chemistry.2013
- Author(s)
  Miyamoto F, Kodama EN
- Journal Title
  
  Curr Pharm Des.
  
  Volume: 19 Pages: 1827-1834
- DOI
  10.2174/1381612811319100007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636
[Journal Article] HIV-1 resistance mechanism to an electrostatically constrained peptide fusion inhibitor that is active against T-20-resistant strains2013
- Author(s)
  Kazuki Shimane, KumiKawaji, Fusako Miyamoto, Shinya Oishi, Kentaro Watanabe, YasukoSakagami, Nobutaka Fujii, Kazuya Shimura, Masao Matsuoka, Mitsuo Kaku, Stefan Sarafianos, and Eiichi Kodama
- Journal Title
  
  Antimicrob Agents Chemother
  
  Volume: 57 Pages: 4035-4038
- DOI
  10.1128/aac.00237-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254, KAKENHI-PROJECT-24791021
[Journal Article] Effects of substitutions at the 4' and 2 positions on the bioactivity of 4'-ethynyl-2-fluoro-2'-deoxyadenosine2013
- Author(s)
  Kirby KA, Michailidis E, Fetterly TL, Steinbach MA, Singh K, Marchand B, Leslie MD, Hagedorn AN, Kodama EN, Marquez VE, Hughes SH, Mitsuya H, Parniak MA, Sarafianos SG.
- Journal Title
  
  Antimicrobal Agents and Chemotherapy
  
  Volume: 57 Pages: 6254-6264
- DOI
  10.1128/aac.01703-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Development of Small Molecule HIV-1 Fusion Inhibitors: Linking Biology to Chemistry.2012
- Author(s)
  Miyamoto F, Kodama EN.
- Journal Title
  
  Curr Pharm Des.
  
  Volume: 19 Pages: 1827-1834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] HIV-1 re- verse transcriptase (RT) polymorphism 172K suppresses the effect of clinically relevant drug resistance mutations to both nucleoside and non-nucleoside RT inhibitors2012
- Author(s)
  Hachiya A, Marchand B, Kirby KA, Michailidis E, Tu X, Palczewski K, Ong YT, Li Z, Griffin DT, Schuckmann MM, Tanuma J, Oka S, Singh K, Kodama EN, Sarafianos SG.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 287 Pages: 29988-29999
- DOI
  10.1074/jbc.m112.351551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636, KAKENHI-PROJECT-24390254
[Journal Article] Biochemical,inhibition and inhibitor resistancestudies of xenotropic murine leukemiavirus-related virus reversetranscriptase.2012
- Author(s)
  Tanyaradzwa P. Ei-Ichi Kodama, et al.
- Journal Title
  
  Nucleic Acids Res
  
  Volume: 40 Pages: 345-359
- DOI
  10.1093/nar/gkr694
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636, KAKENHI-PROJECT-24659484
[Journal Article] Effect of translocation defective reverse transcriptase inhibitors on the activity of N348I, a connection subdomain drug resistant HIV-1 reverse transcriptase mutant.2012
- Author(s)
  Michailidis E, Singh K, Ryan EM, Hachiya A, Ong YT, Kirby KA, Marchand B, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG
- Journal Title
  
  Cell Mol Biol (Noisy-le-grand).
  
  Volume: 58 Pages: 187-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Development and application of fluorescent SDF-1 derivatives.2012
- Author(s)
  Ryo Masuda, Shinya Oishi, Noriko Tanahara, Hiroaki Ohno, Akira Hirasawa, Gozoh Tsujimoto, Eiichi Kodama, Masao Matsuoka and Nobutaka Fujii
- Journal Title
  
  Future Med Chem.
  
  Volume: 4 Pages: 837-844
- NAID
  120005285488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Effect of translocation defective reverse transcriptase inhibitors on the activity of N348I, a connection subdomain drug resistant HIV-1 re- verse transcriptase mutant2012
- Author(s)
  Michailidis E, Singh K, Ryan EM, Hachiya A, Ong YT, Kirby KA, Marchand B, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG.
- Journal Title
  
  Cell Mol Biol(Noisy-le-grand)
  
  Volume: 58 Pages: 187-195
- DOI
  10.1155/2012/586401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636
[Journal Article] Development and application of fluorescent SDF-1 derivatives.2012
- Author(s)
  Masuda R, Oishi S, Tanahara N, Ohno H, Hirasawa A, Tsujimoto G, Kodama E, Matsuoka M, Fujii N.
- Journal Title
  
  Future Medicinal Chemistry
  
  Volume: 4 Pages: 837-844
- DOI
  10.4155/fmc.12.31
- NAID
  120005285488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390025, KAKENHI-PROJECT-23590636, KAKENHI-PROJECT-23659038, KAKENHI-PROJECT-23689007
[Journal Article] Biochemical, inhibition, and inhibitor resistance studies of xenotropic murine leukemia virus-related virus reverse transcriptase.2012
- Author(s)
  TP. Ndongwe, AO. Adedeji, E Michailidis, YT Ong, A Hachiya, B Marchand, EM. Ryan, DK. Rai, KA. Kirby, AS. Whatley, DH. Burke, M Johnson, S Ding, YM Zheng, SL Liu, E Kodama, KA. Delviks-Frankenberry, VK. Pathak, H Mitsuya, MA. Parniak, K Singh, SG. Sarafianos.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 40 Pages: 345-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390254
[Journal Article] Epigallocatechin gallate inhibits the HIV reverse transcription step2011
- Author(s)
  Li S, Hattori T, Kodama EN
- Journal Title
  
  Antivir Chem Chemother.
  
  Volume: 21 Pages: 239-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23256004
[Journal Article] The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase2011
- Author(s)
  Karen A. Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N. Kodama, Noriyuki Ashida, Hiroaki Mitsuya, Michael A. Parniak, Stefan G. Sarafianos
- Journal Title
  
  Cellular and Molecular Biology
  
  Volume: 57 Pages: 39-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Epigallocatechin gallate inhibits HIV reverse transcription step2011
- Author(s)
  Shenwei Li, Toshio Hattori, Eiichi N Kodama
- Journal Title
  
  Antiviral Chemistry and Chemotherapy
  
  Volume: 21 Pages: 239-243
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism2011
- Author(s)
  Hachiya A, Kodama EN, Schuckmann MM, Kirby KA, Michailidis E, Sakagami Y, Oka S, Singh K, Sarafianos SG
- Journal Title
  
  PLoS One
  
  Volume: 6(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636
[Journal Article] K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism.2011
- Author(s)
  Atsuko Hachiya, Eiichi N.Kodama, Matthew M.Schuckmann, Karen A.Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G.Sarafianos
- Journal Title
  
  PLoS One
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] K70Q adds high-level tenofovir resistance to "Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism2011
- Author(s)
  Atsuko Hachiya, Eiichi N.Kodama, Matthew M.Schuckmann, Karen A.Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G.Sarafianos
- Journal Title
  
  PLoS One
  
  Volume: 6
- DOI
  10.1371/journal.pone.0016242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effect on T-202011
- Author(s)
  Kazuki Izumi, Kentaro Watanabe, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka, Stefan G. Sarafianos and Eiichi N. Kodama
- Journal Title
  
  Antiviral Chemistry and Chemotherapy
  
  Volume: 22 Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Potent anti-HIV-1 activity of N-HR-derived pep tides including a deep pocket-forming region without antagonistic effect on T-202011
- Author(s)
  Kazuki Izumi, Kentaro Watanabe, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka, Stefan G.Sarafianos, Eiichi N.Kodama
- Journal Title
  
  Antiviral Chemistry and Chemotherapy
  
  Volume: 22 Pages: 51-55
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] K70Q adds high-level tenofovir resistance to"Q151M complex" HIV reverse transcriptase through the enhanced discrimination mechanism2011
- Author(s)
  Atsuko Hachiya, Eiichi N. Kodama, Matthew M. Schuckmann, Karen A. Kirby, Eleftherios Michailidis, Yasuko Sakagami, Shinichi Oka, Kamalendra Singh, Stefan G. Sarafianos
- Journal Title
  
  PLoS One
  
  Volume: 6 Pages: 16242-16242
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] The Sugar Ring Conformation of 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine and its Recognition by the Polymerase Active Site of HIV Reverse Transcriptase.2011
- Author(s)
  Karen A.Kirby, Kamalendra Singh, Eleftherios Michailidis, Bruno Marchand, Eiichi N.Kodama, Noriyuki Ashida, Hiroaki Mitsuya, Michael A.Parniak, Stefan G.Sarafianos.
- Journal Title
  
  Cellular and Molecular Biology
  
  Volume: 57 Pages: 39-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] The sugar ring conformation of 4'-ethynyl-2-fluoro-2'-deoxyadenosine and its recognition by the polymerase active site of HIV reverse transcriptase2011
- Author(s)
  Kirby KA, Singh K, Michailidis E, Marchand B, Kodama EN, Ashida N, Mitsuya H, Parniak MA, Sarafianos SG
- Journal Title
  
  Cell Mol Biol (Noisy-le-grand)
  
  Volume: 57(1) Pages: 40-6
- URL
  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3119259/
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590636
[Journal Article] Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants.2010
- Author(s)
  Shinya Oishi, Kentaro Watanabe, Saori Ito, Michinori Tanaka, Hiroki Nishikawa, Hiroaki Ohno, Kazuki Shimane, Kazuki Izumi, Yasuko Sakagami, Eiichi N.Kodama, Masao Matsuoka, Akira Asai, Nobutaka Fujii
- Journal Title
  
  Medicinal Chemistry Communications
  
  Volume: 1 Pages: 276-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.2010
- Author(s)
  Matthew Michael Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N.Kodama, Karen A.Kirby, Kamalendra Singh, Stefan G.Sarafianos.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 38700-38709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Resistance profiles of novel electrostatically constrained HIV-1 fusion inhibitors2010
- Author(s)
  Kazuya Shimura, Daisuke Nameki, Keiko Kajiwara, Kentaro Watanabe, Yasuko Sakagami, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka, Stefan G. Sarafianos, Eiichi N. Kodama
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 39471-39480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Rev-derived peptides inhibit HIV 1 replication by antagonism of Rev and a co-receptor, CXCR4.2010
- Author(s)
  Kazuki Shimane, Eiichi N.Kodama, Ikuhiko Nakase, Shiroh Futaki, Yasuteru Sakurai, Yasuko Sakagami, Xiaoguang Li, Toshio Hattori, Stefan G.Sarafianos,Masao Matsuoka
- Journal Title
  
  Internatianal Journal of Biochemistry and Cell Biology
  
  Volume: 42 Pages: 1482-1488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Binding of Multivalent Anionic Porphyrins to V3 Loop Fragments of HIV-1 gp120 and Their Antiviral Activity.2010
- Author(s)
  Kenji Watanabe, Shigeru Negi, Yukio Sugiura, Akiko Kiriyama, Akino Honbo, Katsumi Iga, Eiichi N.Kodama, Takeshi Naitoh, Masao Matsuoka, Koji Kano.
- Journal Title
  
  Chemistry-An Asian Journal 5
  
  Pages: 825-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Binding of Multivalent Anionic Porphyrins to V3 Loop Fragments of HIV-1 gp120 and Their Antiviral Activity.2010
- Author(s)
  Kenji Watanabe, Shigeru Negi, Yukio Sugiura, Akiko Kiriyama, Akino Honbo, Katsumi Iga, Eiichi N.Kodama, Takeshi Naitoh, Masao Matsuoka, Koji Kano
- Journal Title
  
  Chemistry-An Asian Journal
  
  Volume: 5 Pages: 825-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Rev-derived peptides inhibit HIV-1 replication by antagonism of Rev and a co-receptor, CXCR42010
- Author(s)
  Kazuki Shimane, Eiichi N. Kodama, Ikuhiko Nakase, Shiroh Futaki, Yasuteru Sakurai, Yasuko Sakagami, Xiaoguang Li, Toshio Hattori, Stefan G. Sarafianos, Masao Matsuoka
- Journal Title
  
  International Journal of Biochemistry and Cell Biology
  
  Volume: 42 Pages: 1482-1488
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Synthesis and Biological Evaluation of Selective CXCR4 Antagonists Containing Alkene Dipeptide Isosteres2010
- Author(s)
  Tetsuo Narumi, Ryoko Hayashi, Kenji Tomita, Kazuya Kobayashi, Noriko Tanahara, Hiroaki Ohno, Takeshi Naito, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, and Nobutaka Fujii
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 8 Pages: 616-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Synthesis and Biological Evaluatian of Selective CXCR4 Antagonists Containing Alkene Dipeptide Isosteres.2010
- Author(s)
  Tetsuo Narumi, Ryoko Hayashi, Kenji Tomita, Kazuya Kobayashi, Noriko Tanahara, Hiroaki Ohno, Takeshi Naito, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, Nobutaka Fujii
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 8 Pages: 616-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Binding of Multivalent Anionic Porphyrins to V3 Loop Fragments of HIV-1 gp120 and Their Antiviral Activity2010
- Author(s)
  Kenji Watanabe, Shigeru Negi, Yukio Sugiura, Akiko Kiriyama, Akino Honbo, Katsumi Iga, Eiichi N. Kodama, Takeshi Naitoh, Masao Matsuoka, and Koji Kano
- Journal Title
  
  Chemistry-An Asian Journal
  
  Volume: 5 Pages: 825-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine2010
- Author(s)
  Matthew Michael Schuckmann, Bruno Marchand, Atsuko Hachiya, Eiichi N. Kodama, Karen A. Kirby, Kamalendra Singh, Stefan G. Sarafianos
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 38700-38709
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Affinity selection and sequence-activity relationships of HIV-1 membrane fusion inhibitors directed at the drug-resistant variants2010
- Author(s)
  Shinya Oishi, Kentaro Watanabe, Saori Ito, Michinori Tanaka, Hiroki Nishikawa, Hiroaki Ohno, Kazuki Shimane, Kazuki Izumi, Yasuko Sakagami, Eiichi N. Kodama, Masao Matsuoka, Akira Asai and Nobutaka Fujii
- Journal Title
  
  Medicinal Chemistry Communications
  
  Volume: 1 Pages: 276-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Synthesis and Biological Evaluation of Selective CXCR4 Antagonists Containing Alkene Dipeptide Isosteres.2010
- Author(s)
  Tetsuo Narumi, Ryoko Hayashi, Kenji Tomita, Kazuya Kobayashi, Noriko Tanahara, Hiroaki Ohno, Takeshi Naito, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, Nobutaka Fujii.
- Journal Title
  
  Organic & Biomolecular Chemistry 8
  
  Pages: 616-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Resistance profiles of novel electrostatically constrained HIV 1 fusion inhibitors.2010
- Author(s)
  Kazuya Shimura, Daisuke Nameki, Keiko Kajiwara, Kentaro Watanabe, Yasuko Sakagami, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka, Stefan G.Sarafianos, Eiichi N.Kodama
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285 Pages: 39471-39480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino terminal heptad repeat.2010
- Author(s)
  Kazuki Izumi, Shota Nakamura, Hiroaki Nakano, Kazuya Shimura, Yasuko Sakagami, Shinya Oishi, Susumu Uchiyama, Tadayasu Ohkubo, Yuji Kobayashi, Nobutaka Fujii, Masao Matsuoka, Eiichi N.Kodama
- Journal Title
  
  Antiviral Research
  
  Volume: 87 Pages: 179-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino terminal heptad repeat2010
- Author(s)
  Kazuki Izumi, Shota Nakamura, Hiroaki Nakano, Kazuya Shimura, Yasuko Sakagami, Shinya Oishi, Susumu Uchiyama, Tadayasu Ohkubo, Yuji Kobayashi, Nobutaka Fujii, Masao Matsuoka, Eiichi N. Kodama
- Journal Title
  
  Antiviral Research
  
  Volume: 87 Pages: 179-186
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Procyanidin B-1 purified from Cinnamomi Cortex suppresses HCV replication2010
- Author(s)
  Shenwei Li, Eiichi N Kodama, Yuuki Inoue, Hideki Tani, Yoshiharu Matsuura, Jing Zhang, Takashi Tanaka, Toshio Hattori
- Journal Title
  
  Antiviral Chemistry and Chemotherapy
  
  Volume: 20 Pages: 239-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article]2010
- Author(s)
  児玉栄一, 他
- Journal Title
  
  新規抗HIV薬の開発特集・抗ウイルス薬物療法の現状と今後の展望(医薬ジャーナル)
  
  Pages: 99-102
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-ethynyl-2-fluoro-2'-doxyadenosine triphosphate, a translocation defective reverse transcriptase inhibitor.2009
- Author(s)
  Eleftherios Michailidis, Bruno Marchand, Eiichi N.Kodama, Kamlendra Singh, Masao Matsuoka, Karen A.Kirby, Emily M.Ryan, Ali M.Sawani, Eva Nagy, Noriyuki Ashida, Hiroaki Mitsuya, Michael A.Parniak, Stefan G.Sarafianos.
- Journal Title
  
  Journal of Biological Chemistry 284
  
  Pages: 35681-35691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Electrostatically constrained α-helical peptide inhibits replication of HIV-1 resistant to enfuvirtide.2009
- Author(s)
  Hiroki Nishikawa, Shota Nakamura, Eiichi Kodama, Saori Ito, Keiko Kajiwara, Kazuki Izumi, Yasuko Sakagami, Shinya Oishi, Tadayasu Ohkubo, Yuji Kobayashi, Akira Otaka, Nobutaka Fujii, Masao Matsuoka
- Journal Title
  
  International Journal of Biochemistry and Cell Biology 41
  
  Pages: 891-899
- NAID
  120002790064
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] X-ray Crystallographic Study of an HIV-1 Fusion Inhibitor with the gp41 S138A Substitution.2009
- Author(s)
  Tsuyoshi Watabe, Yukihiro Terakawa, Kentaro Watanabe, Hiroaki Ohno, Hiroaki Nakano, Toru Nakatsu, Hiroaki Kato, Kazuki Izumi, Eiichi Kodama, Masao Matsuoka, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii.
- Journal Title
  
  Journal of Molecular Biology 392
  
  Pages: 657-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Bioorganic Synthesis of a Recombinant HIV-1 Fusion Inhibitor, SC35EK, with an N-Terminal Pyroglutamate Capping Group2009
- Author(s)
  Kazumi Kajiwara, Kentaro Watanabe, Rei Tokiwa, Tomoko Kurose, Hiroaki Ohno, Hiroko Tsutsumi, Yoji Hata, Kazuki Izumi, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, and Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 17
- NAID
  120002098852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Mechanism of inhibition of HIV-1 reverse transcriptase by 4'-ethynyl-2-fluoro-2'-doxyadenosine triphosphate, a translocation defective reverse transcriptase inhibitor2009
- Author(s)
  Eleftherios Michailidis, Bruno Marchand, Eiichi N. Kodama, Kamlendra Singh, Masao Matsuoka, Karen A. Kirby, Emily M. Ryan, Ali M. Sawani, Eva Nagy, Noriyuki Ashida, Hiroaki Mitsuya, Michael A. Parniak, and Stefan G. Sarafianos
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 284 Pages: 35681-35691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Clinical relevance of substitutions in the connection subdomain and R Nase H domains of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naive patients.2009
- Author(s)
  Atsuko Hachiya, Kazuki Shimane, Stefan G.Sarafianos, Eiichi N.Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka.
- Journal Title
  
  Antiviral Research 82
  
  Pages: 115-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Peptide bond mimicry by(E)-alkene and(Z)-fluoroalkene peptide isosteres : synthesis and bioevaluation of alpha-helical anti-HIV peptide analogues2009
- Author(s)
  Shinya Oishi, Hirotaka Kamitani, Yasuyo Kodera, KentaroWatanabe, Kazuya Kobayashi, Tetsuo Narumi, Kenji Tomita, Hiroaki Ohno, Takeshi Naito, Eiichi Kodama, Masao Matsuoka and Nobutaka Fujii
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 7 Pages: 2872-2877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article]2009
- Author(s)
  児玉栄一、服部俊夫, 他
- Journal Title
  
  HIV感染症と増殖のメカニズム-抗ウイルス剤の作用点を中心に- 特集HIV感染症流行の現状と最新の治療(日本内科学会雑誌)
  
  Pages: 2754-2761
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Clinical relevance of substitutions in the connection subdomain and RNase H domains of HIV-1 reverse transcriptase from a cohort of antiretroviral treatment-naive patients2009
- Author(s)
  Atsuko Hachiya, Kazuki Shimane, Stefan G. Sarafianos, Eiichi N. Kodama, Yasuko Sakagami, Fujie Negishi, Hirokazu Koizumi, Hiroyuki Gatanaga, Masao Matsuoka, Masafumi Takiguchi, Shinichi Oka
- Journal Title
  
  Antiviral Research
  
  Volume: 82 Pages: 115-121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Bioorganic Synthesis of End-capped Anti-HIV Peptides by Simultaneous Cyanocysteine-mediated Cleavages of Recombinant Proteins2009
- Author(s)
  Michinori Tanaka, Kazumi Kajiwara, Rei Tokiwa, Kentaro Watanabe, Hiroaki Ohno, Hiroko Tsutsumi, Yoji Hata, Kazuki Izumi, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 17 Pages: 7487-7492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres : synthesis and bioevaluation of alpha-helical anti-HIV peptide analogues.2009
- Author(s)
  Shinya Oishi, Hirotaka Kamitani, Yasuyo Kodera, Kentaro Watanabe, Kazuya Kobayashi, Tetsuo Narumi, Kenji Tomita, Hiroaki Ohno, Takeshi Naito, Eiichi Kodama, Masao Matsuoka, Nobutaka Fujii
- Journal Title
  
  Organic & Biomolecular Chemistry 7
  
  Pages: 2872-2877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] SC29EK, a peptide fusion inhibitor with enhanced α-helicity, inhibits replication of human immunodeficiency virus type 1 mutants resistant to enfuvirtide.2009
- Author(s)
  akeshi Naito, Kazuki Izumi, Eiichi Kodama, Yasuko Sakagami, Keiko Kajiwara, Hiroki Nishikawa, Kentaro Watanabe, Stefan G.Sarafianos, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka.
- Journal Title
  
  Antimicrobal Agents and Chemotherapy 53
  
  Pages: 1013-1018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Bioorganic Synthesis of End-capped Anti-HIV Peptides by Simultaneous Cyanocysteine-mediated Cleavages of Recombinant Proteins.2009
- Author(s)
  Michinori Tanaka, Kazumi Kajiwara, Rei Tokiwa, Kentaro Watanabe, Hiroaki Ohno, Hiroko Tsutsumi, Yoji Hata, Kazuki Izumi, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry 17
  
  Pages: 7487-7492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Synonymous mutations in stem-loop III of Rev responsive elements enhance HIV-1 replication impaired by primary mutations for resistance to enfuvirtide.2009
- Author(s)
  Mariko Ueno, Eiichi N.Kodama, Kazuya Shimura, Yasuteru Sakurai, Keiko Kajiwara, Yasuko Sakagami, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka.
- Journal Title
  
  Antiviral Research 82
  
  Pages: 67-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Design of peptide-based inhibitors for HIV-1 strains resistant to T-202009
- Author(s)
  Kazuki Izumi, Eiichi Kodama, Kazuya Shimura, Yasuko Sakagami, Kentaro Watanabe, Saori Ito, Tsuyoshi Watabe, Yukihiro Terakawa, Hiroki Nishikawa, Stefan G.Sarafianos, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii, Masao Matsuoka
- Journal Title
  
  Journal of Biological Chemistry 284
  
  Pages: 4914-4920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus2009
- Author(s)
  Shinya Oishi, Yasuyo Kodera, Hiroki Nishikawa, Kamitani H, Tsuyoshi Watabe, Hiroaki Ohno, Tadafumi Tochikura, Kazuki Shimane, Eiichi Kodama, Masao Matsuoka, Fuminori Mizukoshi, Hajime Tsujimoto H, Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 17 Pages: 4916-4920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Design and synthesis of membrane fusion inhibitors against the feline immunodeficiency virus.2009
- Author(s)
  Shinya Oishi, Yasuyo Kodera, Hiroki Nishikawa, Kamitani H, Tsuyoshi Watabe, Hiroaki Ohno, Tadafumi Tochikura, Kazuki Shimane, Eiichi Kodama, Masao Matsuoka, Fuminori Mizukoshi, Hajime Tsujimoto H, Nobutaka Fujii
- Journal Title
  
  Bioorganic & Medicinal Chemistry 17
  
  Pages: 4916-4920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Bioorganic Synthesis of a Recombinant HIV-1 Fusion Inhibitor, SC35EK, with an N-Terminal Pyroglutamate Capping Group.2009
- Author(s)
  Kazumi Kajiwara, Kentaro Watanabe, Rei Tokiwa, Tomoko Kurose, Hiroaki Ohno, Hiroko Tsutsumi, Yoji Hata, Kazuki Izumi, Eiichi Kodama, Masao Matsuoka, Shinya Oishi, Nobutaka Fujii.
- Journal Title
  
  Bioorganic & Medicinal Chemistry 17
  
  Pages: 7964-7970
- NAID
  120002098852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] X-ray Crystallographic Study of an HIV-1 Fusion Inhibitor with the gp41 S138A Substitution2009
- Author(s)
  Tsuyoshi Watabe, Yukihiro Terakawa, Kentaro Watanabe, Hiroaki Ohno, Hiroaki Nakano, Toru Nakatsu, Hiroaki Kato, Kazuki Izumi, Eiichi Kodama, Masao Matsuoka, Kazuo Kitaura, Shinya Oishi, Nobutaka Fujii
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 392 Pages: 657-665
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590591
[Journal Article] Potent anti-HIV-1 activity of N-HR-derived peptides including a deep pocket-forming region without antagonistic effects
- Author(s)
  Watanabe K, Oishi S, Fujii on T-20.Izumi K, N, Matsuoka M, Sarafianos SG, Kodama EN
- Journal Title
  
  Antivir Chem
- DOI
  10.3851/imp1836
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] Development of cell encapsulated gel system for secretion offunctional exosomes in cell therapy.2018
- Author(s)
  Mami Hirano, Masaya Hagiwara, Nahoko Bailey Kobayashi, Tetsuhiko Yoshida, Eiichi N.Kodama, and Ikuhiko Nakase.
- Organizer
  The 24th Peptide Forum in Kyoto 2018
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] 生合成経路の再構築と再設計による糸状菌ジテルペノイドピロンライブラリーの構築と生物活性評価2018
- Author(s)
  塚田健人，金子秋穂，新木翔之，河治久実，児玉栄一，倉石貴透，村上一馬，入江一浩，平田尚也，諫田泰成，浅井禎吾
- Organizer
  第36回メディシナルケミストリーシンポジウム　日本薬学会　医薬化学部会
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] ウイルスポリメラーゼの不可逆阻害を目指した新規2'-b-セレノ核酸アナログの創製2018
- Author(s)
  村上　努, 木村康明, 新美結士, 藤野真之, 片倉秀雄, 鈴木哲朗, 児玉栄一, 阿部　洋
- Organizer
  第32回日本エイズ学会
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] Characterization of novel HIV-1 inhibitorstargeting Gag-TSG101 interaction.2018
- Author(s)
  Siarot Lowela, Chutiwitoonchai Nopporn, 佐藤洋隆, Chang Hao, 小谷治, 横山勝, 佐藤裕徳, 藤野真之, 村上努, 近藤恭光, 本田香り, 長田裕之, 上田一樹, 伊藤嘉浩, 青野俊裕, 児玉栄一, 黒田和道, 武井正美, 間陽子
- Organizer
  第32回日本エイズ学会
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] Development of 2-beta Seleno Nucleoside Analogs as Irreversible Inhibitors for Viral Polymerases2018
- Author(s)
  Yasuaki Kimura, Yushi Niimi, Hideo Katakura, Tetsuro Suzuki, Tsutomu Murakami, EiichiKodama, Hiroshi Abe
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] ゲンボイヤ配合錠（GEN;EVG/COBI/FTC/TAF）投与時の耐性発現症例の検討2017
- Author(s)
  田沼順子，潟永博之，岡慎一，児玉栄一，中本泰充，池田篤史，小倉直樹，Michael E. Abram，Nicolas A. Margot，Stephanie Cox，Christian Callebaut，Moupali Das
- Organizer
  第31回日本エイズ学会
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] Characteristics of Hospital Damage and Challenges of Disaster Mitigation Related to the 2016Kumamoto Earthquakes in Japan.2017
- Author(s)
  Hitomi Maeda, Satoko Iyama, Chiharu Matsumoto, Kimiyo Nanke and Eiichi Kodama
- Organizer
  International Nursing Research Conference 2017
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] tructural Basis of Inhibitionand Resistance Mechanism to EFdA,a highly potent NRTI2016
- Author(s)
  Zhe Li, Karen A. Kirby, Bruno Marchand, Eleftherios Michailidis, Eiichi N.Kodama, Lisa C.Rohan, Hiroaki Mitsuya, Michael A. Parniak, and Stefan G. Sarafianos.
- Organizer
  Cold Spring Harbor Laboratory Meetings Retroviruses
- Place of Presentation
  Ｎｅｗ　Ｙｏｒｋ　Ｃｉｔｙ（ＵＳＡ）
- Year and Date
  2016-05-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] ジョロウグモ内生糸状菌のポストゲノム型天然物探索2016
- Author(s)
  浅井禎吾，塚田健人，森下陽平，伊藤史織，網谷雄志，岡崎裕亮，児玉栄一，大島吉輝
- Organizer
  第58回天然物有機化合物討論会
- Place of Presentation
  仙台
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16H05346
[Presentation] Profile of a novel HIV reverse　transcriptase inhibitor2013
- Author(s)
  Fusako Miyamoto, Fumiko Tomiyama, Kumi Kawaji, Mitsuo Kaku, Eiichi Kodama
- Organizer
  NIH Tohoku University JSPS Symposium
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24390254
[Presentation] The Combination of 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine with Rilpivirine Shows Synergistic Anti-HIV-1 Activ- ity In Vitro2012
- Author(s)
  Atsuko Hachiya, Bruno Marchand, Eleftherios Michailidis, Eiichi N Kodama, Michael A Parni- ak, Hiroaki Mitsuya, Shinichi Oka, Stefan G Sarafianos
- Organizer
  25th In- ternational Conference on Antiviral Research
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] The Combination of 4'-Ethynyl-2-Fluoro-2'-Deoxyadenosine with Rilpivirine Shows Synergistic Anti-HIV-1 Activity In Vitro.2012
- Author(s)
  Atsuko Hachiya, Bruno Marchand, Eleftherios Michailidis, Eiichi N Kodama, Michael A Parniak, Hiroaki Mitsuya, Shinichi Oka, Stefan G Sarafianos.
- Organizer
  25th International Conference on Antiviral Research.
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] Effect of 4'- and 2-NRTI Substitutions on the Inhibition Mechanism of HIV Reverse Transcriptase and Toxicity.2012
- Author(s)
  Eleftherios Michailidis, Jordan Wilkins, Emily M. Ryan, Atsuko Hachiya, Eiichi N. Kodama, Hiroaki Mitsuya, Michael A. Parniak, Stefan G. Sarafianos.
- Organizer
  25th International Conference on Antiviral Research.
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] Effect of 4'- and 2-NRTI Substitu- tions on the Inhibition Mechanism of HIV Re- verse Transcriptase and Toxicity2012
- Author(s)
  Eleftherios Michailidis, Jordan Wilkins, Emily M. Ryan, Atsuko Hachiya, Eiichi N. Kodama, Hiroaki Mitsuya, Michael A. Parniak, Stefan G. Sarafianos
- Organizer
  25th In- ternational Conference on Antiviral Research
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] A novel peptide derived from measles virus fusion protein inhibits the replication of subacute sclerosing panencephalitis (SSPE) virus in vitro and in vivo.2012
- Author(s)
  Masahiro Watanabe, Koichi Hashimoto, Yusaku Abe, Eiichi Kodama, Ryota Nabika, Shinya Oishi, Nobutaka Fujii, Mitsuaki Hosoya
- Organizer
  25th International Conference on Antiviral Research.
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] Sustained Activity of 4'-Ethynyl Nucleosides to Variants with M184V Mutation in HIV-1 Reverse Transcriptase.2012
- Author(s)
  Fusako Miyamoto, Kumi Kawaji, Toshio Hattori, Hiroaki Mitsuya, Stefan G. Sarafianos, Eiichi N. Kodama.
- Organizer
  25th International Conference on Antiviral Research.
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA), a translocation defective reverse transcriptase inhibitor with highly potent activity against diverse multi-drug-resistant HIV-1 variants.2012
- Author(s)
  Hiroaki Mitsuya, Eiichi Kodama, Hirotomo Nakata, Shinichro Hattori, Seiji Okada, Kenji Maeda, Michael A. Parniak, and Stefan G. Sarafianos.
- Organizer
  13th Kmamoto AIDS Seminar-GCOE Joint International Symposium
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] Combinations of 4'-ethynyl-2-fluoro-2'-deoxyadenosine with rilpivirine show synergistic anti-HIV activity in vitro.2012
- Author(s)
  Atsuko Hachiya, Eiichi N. Kodama et al.
- Organizer
  13th Kmamoto AIDS Seminar-GCOE Joint International Symposium
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] Sustained Activity of 4'-Ethynyl Nucleosides to Variants with M184V Mutation in HIV-1 Reverse Transcriptase2012
- Author(s)
  Fusako Miyamoto,Kumi Kawaji,Toshio Hattori, Hiroaki Mitsuya, Stefan G Sarafianos is, Eiichi N Kodama
- Organizer
  25th In- ternational Conference on Antiviral Research
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-23590636
[Presentation] 4'-Ethynyl-核酸誘導体に対するHIV-1およびHIV-2の耐性機序2011
- Author(s)
  宮本総子, 服部俊夫, 児玉栄一
- Organizer
  第25回エイズ学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23256004
[Presentation] Effect of 4'- and 2-NRTI Substitutions on the Inhibition Mechanism of HIV Reverse Transcriptase2011
- Author(s)
  Eleftherios Michailidis, Stephen H.Hughes, Emily M.Ryan, Atsuko Hachiya, Devendra Rai, Jordan Wilkins, Kamlendra Singh, Bruno Marchand, Mark Hannink, B.Christie Vu, Victor Marquez, Ei-Ichi Kodama, Hiroaki Mitsuya, Michael A.Parniak, Stefan G.Sarafianos
- Organizer
  12th Annual Symposium on Antiviral Drug Resistanee
- Place of Presentation
  ペンシルバニアアメリカ
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] HIV-1 Reverse Transcriptase(RT)Polymorphism 172K Suppresses the Effect of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Nonnucleoside RT Inhibitors2011
- Author(s)
  Atsuko Hachiya, Bruno Marchand, Karen A. Kirby, Eleftherios Michailidis, Xiongying Tu, Yee Tsuey Ong, Daniel T. Griffin, Matthew M. Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N. Kodama and Stefan G. Sarafianos
- Organizer
  12th Annual Symposium on Antiviral Drug Resistance, Hershey, Pennsylvania
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] HIV-1 Reverse Transcriptase Polymorphism 172K Suppresses the Effect of Clinical Resistance Mutations to both NRTI and NNRTI2011
- Author(s)
  Atsuko Hachiya, Matthew M. Schuckmann, D Griffin, Karen A. Kirby, YT Ong Junko Tanuma, Shinichi Oka, Kamlendra Singh, Eiichi N. Kodama, Stefan G. Sarafianos
- Organizer
  8th conference on retroviruses and opportunistic infections Boston, MA
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Development of HIV-1 fusion inhibitors active to enfuvirtide resistant variants2011
- Author(s)
  Eiichi N. Kodama
- Organizer
  US-Japan Joint AIDS Panel : Resistance Meeting, Singapore
- Place of Presentation
  Invited
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] HIV-1 Reverse Transcriptase (RT) Polymorphism 172K Suppresses the Effeet of Clinically Relevant Drug Resistance Mutations to Both Nucleoside and Nonnucleoside RT Inhibitors2011
- Author(s)
  Atsuko Hachiya, Bruno Marchand, Karen A.Kirby, Eleftherios Michailidis, Xiongying Tu, Yee Tsuey One, Daniel T.Griffin, Matthew M.Schuckmann, Junko Tanuma, Shinichi Oka, Kamalendra Singh, Eiichi N.Kodama, Stefan G.Sarafianos
- Organizer
  12th Annual Symposium on Antiviral Drug Resistanee
- Place of Presentation
  ペンシルバニアアメリカ
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] HIV-1 Reverse Transcriptase Polymorphism 172K Suppresses the Effect of Clinical Resistance Mutations to both NRTI and NNRTI.2011
- Author(s)
  Atsuko Hachiya, Matthew M.Schuckmann, D Griffin, Karen A.Kirby, YT Ong Junko Tanuma, Shinichi Oka, Kamlendra Singh, Eiichi N.Kodama, Stefan G.Sarafianos.
- Organizer
  18th conference on retroviruses and opportunistic infections Boston, MA
- Place of Presentation
  ボストン、アメリカ
- Year and Date
  2011-02-27
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Effect of 4'-and2-NRTI Substitutions on the Inhibition Mechanism of HIV Reverse Transcriptase2011
- Author(s)
  Eleftherios Michailidis, Stephen H. Hughes, Emily M. Ryan, Atsuko Hachiya, Devendra Rai, Jordan Wilkins, Kamlendra Singh, Bruno Marchand, Mark Hannink, B. Christie Vu, Victor Marquez, Ei-Ichi Kodama, Hiroaki Mitsuya, Michael A. Parniak, and Stefan G. Sara
- Organizer
  12th Annual Symposium on Antiviral Drug Resistance, Hershey, Pennsylvania
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Development of HIV-1 fusion inhibitors active to enfuvirtide resistant variants.2010
- Author(s)
  Eiichi N.Kodama
- Organizer
  US-Japan Joint AIDS Panel : Resistance Meeting, Singapore
- Place of Presentation
  シンガポール Grans Copthorne Waterfront Hotel(招待講演)
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Parniak 4'-Ethynyl-2-fluoro-2'-deoxyadenosine(EFDA), a translocation defective reverse transcriptase inhibitor with highly potent activity against diverse multi-drug-resistant HIV-1 variants2009
- Author(s)
  Hiroaki Mitsuya, Stefan G. Sarafianos, Eiichi Kodama, Hirotomo Nakata, Seiji Okada, and Michael A
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance, Richmond, VA
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Drug design for resistant HIV2009
- Author(s)
  Kodama E.
- Organizer
  10th Kumamoto AIDS seminar/AIDS GCOE International Symposium Satellite symposium
- Place of Presentation
  熊本(招待講演)
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] The NNRTI-resistant Y181C HIV-1 reverse transcriptase is hyper-susceptible to 4'-ethynyl-2-fluoro deoxyadenosine(EFDA)2009
- Author(s)
  Yee Tsuey Ong, Eleftherios Michailidis, Bruno Marchand, Matthew S. Schuckmann, Kamlendra Singh, Ei-Ichi Kodama, Masao Matsuoka, Hiroaki Mitsuya, Eva Nagy, Michael A. Parniak, and Stefan G. Sarafianos
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance, Richmond, VA
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Parniak 4'-Ethynyl-2-fluoro-2'-deoxyadenosine(EFDA), a translocation defective reverse transcriptase inhibitor with highly potent activity against diverse multi-drug-resistant HIV-1 variants.2009
- Author(s)
  Hiroaki Mitsuya, Stefan G.Sarafianos, Eiichi Kodama, Hirotomo Nakata, Seiji Okada, Michael A.
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance
- Place of Presentation
  アメリカ、リッチモンド
- Year and Date
  2009-11-15
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Drug design for resistant HIV2009
- Author(s)
  Kodama E
- Organizer
  10th Kumamoto AIDS seminar/AIDS GCOE International Symposium Satellite symposium, Kumamoto, Japan
- Place of Presentation
  Invited
- Year and Date
  2009-09-30
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] K70Q expands multi-drug resistance (MDR) of HIV-1 containing "Q151M complex" reverse transcriptase mutations.2009
- Author(s)
  Atsuko Hachiya, Eiichi N.Kodama, Matthew M.Schuckmann, Karen A.Kirby, Eleftherios Michailidis, Yasuko Sakagami, Kamlendra Singh, Shinichi Oka, Stefan G.Sarafianos.
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance
- Place of Presentation
  アメリカ、リッチモンド
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] K70Q expands multi-drug resistance(MDR)of HIV-1 containing"Q151M complex" reverse transcriptase mutations2009
- Author(s)
  Atsuko Hachiya, Eiichi N. Kodama, Matthew M. Schuckmann, Karen A. Kirby, Eleftherios Michailidis, Yasuko Sakagami, Kamlendra Singh, Shinichi Oka, and Stefan G. Sarafianos
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance, Richmond, VA
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] The NNRTI-resistant Y181C HIV-1 reverse transcriptase is hyper-susceptible to 4'-ethynyl-2-fluoro deoxyadenosine(EFDA)2009
- Author(s)
  Yee Tsuey Ong, Eleftherios Michailidis, Bruno Marchand, Matthew S.Schuckmann, Kamlendra Singh, Ei-Ichi Kodama, Masao Matsuoka, Hiroaki Mitsuya, Eva Nagy, Michael A.Parniak, Stefan G.Sarafianos.
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance
- Place of Presentation
  アメリカ、リッチモンド
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Biochemical characterization of the HIV reverse transcriptase connection domain multi-class drug resistance mutation N348I2009
- Author(s)
  Matthew Schuckmann, Atsuko Hachiya, Ei-ichi N. Kodama, Bruno Marchand, Eleftherios Michailidis, Kamlendra Singh, Yasuko Sakagami, Shinichi Oka, and Stefan G. Sarafianos
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance, Richmond, VA
- Place of Presentation
  USA
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Biochemical characterization of the HIV reverse transcriptase connection domain multi-class drug resistance mutation N348I.2009
- Author(s)
  Matthew Schuckmann, Atsuko Hachiya, Ei-ichi N.Kodama, Bruno Marchand, Eleftherios Michailidis, Kamlendra Singh, Yasuko Sakagami, Shinichi Oka, Stefan G.Sarafianos.
- Organizer
  10th Annual Symposium on Antiviral Drug Resistance
- Place of Presentation
  アメリカ、リッチモンド
- Year and Date
  2009-11-16
- Data Source
  KAKENHI-PROJECT-21590591
[Presentation] Structural Basis of Inhibition and Resistance Mechanism to EFdA, a Highly Potent NRTI.
- Author(s)
  Zhe Li, Karen Kirby, Bruno Marchand, Michailidis Eleftherios, Eiichi Kodama, Hiroaki Mitsuya, Michael Parniak, Stefan Sarafianos.
- Organizer
  The annual Conference on Retroviruses and Opportunistic Infections
- Place of Presentation
  シアトル・アメリカ
- Year and Date
  2015-02-23 – 2015-02-26
- Data Source
  KAKENHI-PROJECT-25670255
[Presentation] Structural Basis of Inhibition and Resistance Mechanism to EFdA, a Highly Potent NRTI.
- Author(s)
  Zhe Li, Karen Kirby, Bruno Marchand, Michailidis Eleftherios, Eiichi Kodama, Hiroaki Mitsuya, Michael Parniak, Stefan Sarafianos.
- Organizer
  The annual Conference on Retroviruses and Opportunistic Infections
- Place of Presentation
  シアトル・アメリカ
- Year and Date
  2015-02-23 – 2015-02-26
- Data Source
  KAKENHI-PROJECT-24390254

1. 浅井禎吾 (60572310)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. HATTORI Toshio (30172935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. NIKI Toshiro (40558508)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HIRASHIMA Mitsuomi (70109700)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. HAORILE Chagan-Yasutan (50624821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KUBO Toru (50444873)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. ASHINO Yugo (20361082)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. UENO Takamasa (10322314)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 松岡雅雄 (10244138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 大島吉輝 (00111302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 菊地晴久 (90302166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 林宏典 (00752916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中瀬生彦 (40432322)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 萩原将也 (00705056)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 上田真史 (40381967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Maeda Kenji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. MURAKAMI Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. FUJINO Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. SHIMURA Kazuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. OHKAWA Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. IMADOME Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. HIROSHI Kimura

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 満屋裕明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
24. 近藤恭光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 青木学

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 中田浩智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 間陽子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 藤井信孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
29. 大石真也

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 越後貫成美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 畑中勇輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 束田裕一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 小倉淳郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 新井文子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 大野浩章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kodama Eiichi 児玉 栄一

KODAMA Eiichi 児玉 栄一

児玉 栄一 コダマ エイイチ

Research Projects

Research Products

Co-Researchers

ストレス応答生合成と化学修飾を融合した多様性天然物による難治性疾患治療薬の開発Principal InvestigatorOngoing

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Review Section

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細胞治療を指向した機能性エクソソーム分泌細胞内包ゲルの開発Ongoing

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Novel screenings for unmet medical needs with innovative new natural product derived compoundsPrincipal Investigator

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Development of antiviral agents targeting ATP-mediated excisionPrincipal Investigator

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Development of anti-HIV agents that exert synergism with host immune pressurePrincipal Investigator

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Clinical Utilities of new biomarker for dengue virus infection

Principal Investigator

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Mechanism of resistance to translocation defective reverse transcriptase inhibitors

Principal Investigator

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Effect of a novel resistance associated mutation, N348I, which has been identified in Japanese HIV-1 infected patients, on the reverse transcriptase activity.Principal Investigator

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Establishment of Rev based anti-HIV therapy.Principal Investigator

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ヘルペスウイルスを標的とした新規治療薬開発による難治性腫瘍克服

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ヒト免疫不全症ウイルス・細胞融合機構の解明と治療への応用Principal Investigator

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新規HIV複製ステップの同定及びその阻害剤開発への応用Principal Investigator

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Review Section

Research Institution

新規HIV複製ステップの同定及びその阻害剤開発への応用Principal Investigator

Principal Investigator

Kodama Eiichi 児玉栄一

KODAMA Eiichi 児玉栄一

児玉栄一コダマエイイチ

[Journal Article] Inhibition of the DNA　polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1　replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki)　components2015