Futaki Shiroh 二木史朗

… Alternative Names

Researcher Number	50199402
Other IDs	https://orcid.org/0000-0002-0124-4002
External Links
Affiliation (Current)	2020: 京都大学, 化学研究所, 教授
Affiliation (based on the past Project Information) *help	2011 – 2020: 京都大学, 化学研究所, 教授 2005 – 2009: 京都大学, 化学研究所, 教授 1997 – 2004: 京都大学, 化学研究所, 助教授 1993 – 1996: 徳島大学, 薬学部, 助教授 1992 – 1993: 徳島大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Science and Engineering / Chemical pharmacy / Drug development chemistry / Bioorganic chemistry / 医薬分子機能学 / Biomolecular chemistry / Living organism molecular science / Medium-sized Section 47:Pharmaceutical sciences and related fields Except Principal Investigator Obstetrics and gynecology / Chemical pharmacy … More
Keywords	Principal Investigator 細胞内送達 / イオンチャネル / ペプチド / 合成ペプチド / ペプチド工学 / 薬物送達 / 細胞 / エンドサイトーシス / 人工蛋白質 / アルギニンペプチド … More Except Principal Investigator 亜鉛フィンガー / 抗精子抗体 / イムノグロブリン結合因子 / antisperm antibody / immunoglobulin binding factor / 転写因子 / 精漿 / プロテイン・ジスルフィド・イソメラーゼ / 分子シャペロン / 子宮頸管 / uterine cervical gland / molecular chaperon / protein disulfide isomerase / DNA湾曲 / Zinc finger / DNA bending / 核酸認識 / 金属ペプチド / モチーフ / 分子認識 / ABCトランスポーター / MDR1 / ファージディスプレイ / ATPaseドメイン / ATP阻害剤 / ペプチド / 阻害剤 / FRET / FRAP / エストロゲン受容体 / アンドロゲン受容体 / 細胞質・核移行 / インポーティン / RanGTP / リガンド / 脂溶性リガンド / 分子相関 / 受容体 / 培養 / セミインタクト細胞 / 強制発現 / 糖漿 / Fcレセプター / IgG / 免疫抑制 / 前立腺 / 外分泌腺 / 精子抗原 / seminal plasma / Fc receptor / immunoglobulin G / immunosuppression / prostate / cervical mucous / 精子付着抗原 / 子宮頸管腺 / トリプターゼ / 分子シャベロン / 不妊症 / 局所免疫 / 頸管粘液 / 気管 / 喫煙 / 蛋白分解酵素 / アルギニールエンドペプチダーゼ / sperm coating antigen / tryptase / seminal plasmacervical mucous / エストロゲン / プロゲステロン / プロテイン・ジスルフィドイソメラーゼ / ホルモン補充療法 / プロテアゾーム / 性ステロイドホルモン / プロテインジスルフィドイソメラーゼ / 子宮剄質 / 性周期 / estrogen / progesterone / hormone replacenment therapy / アーキテクチャー / DNA結合 / マルチフィンガー / 遺伝子制御 / 動力学 / Transcription factor / Architecture / DNA binding / Multifinger / Gene regulation / Kinetic / 遺伝子ターゲット / 人工タンパク質 / 人工制限酵素 / 人工リプレッサー / DNA認識 / DNAモチーフ / Artificial protein / DNA recognition / DNA motif / Gene target / Artificial restriction enzyme / Artificial repressor / ユビキチン / ステープルペプチド / ユビキチンシグナル / 炎症シグナル / 直鎖状ユビキチン鎖 Less

生体膜の曲率・脂質パッキング状態変化を誘起する機能性ペプチドと展開Principal InvestigatorOngoing
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
生理活性タンパク質の細胞内移送の新機軸Principal InvestigatorOngoing
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
生物機能中分子の細胞導入の分子基盤Principal InvestigatorOngoing
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kyoto University
生体膜の曲率・脂質パッキング状態変化を誘起する機能性ペプチドPrincipal InvestigatorOngoing
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kyoto University
ケモテクノロジーを利用したユビキチン鎖の機能解析と制御Ongoing
- Principal Investigator
  
  岩井一宏
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツールPrincipal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
生物機能中分子の細胞内への新規導入基盤の創出Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Creation of artificial lligand-sensitive ion-channel using nucleic acid aptamer for extracellular segmentPrincipal Investigator
- Principal Investigator
  
  Shiroh Futaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Kyoto University
New strategy for intracellular delivery of biomacropharmaceuticalsPrincipal Investigator
- Principal Investigator
  
  Futaki Shiroh
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツールPrincipal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Library design and selection for obtaining peptides that target HTLV-1 proteinPrincipal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Kyoto University
Development and application of novel calcium-sensitive protein splicing systemsPrincipal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyoto University
細胞内可視化・ハイスループット検出系創出のための効率的細胞導入法Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Chemical Biology in internalization of membrane-permeable peptidesPrincipal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
バイオセンサーによる細胞内イメージングのための対イオン送達法の最適化Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
FRETとFRAPによる脂溶性リガンド分子と受容体結合の可視化と分子相関解析
- Principal Investigator
  
  河田光博
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Kyoto Prefectural University of Medicine
Development of intracellular targeting peptide vectors and the real-time observation in cells.Principal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  KYOTO UNIVERSITY
ABCタンパク質を制御する細胞浸透性ペプチドの開発
- Principal Investigator
  
  吉村徹
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied biochemistry
- Research Institution
  Nagoya University
ペプチドマトリクスを使った高分子量タンパク質の細胞内送達Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
Design and intracellular delivery of peptides for transcription regulationPrincipal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
膜外シグナルによる膜内ペプチドの会合調節を利用した膜電流制御システムの構築Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
難溶性薬物のキャリアを目指した新規大環状ヘリックス蛋白質の創出Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  医薬分子機能学
- Research Institution
  Kyoto University
Architectures of Transcriptional Regulation : Creation and Functional Analysis of Multi-Zinc Fingers
- Principal Investigator
  
  SUGIURA Yukio
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  KYOTO UNIVERSITY
Design and intracellular delivery of peptides for transcription regulationPrincipal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Development or order-mede type artificial restriction enzymes and artificial repressers
- Principal Investigator
  
  SUGIURA Yukio
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for University and Society Collaboration
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
膜外シグナルによる膜内ペプチドの会合調節を利用した膜電流制御システムの構築Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
DNA・RNAを認識する新しい金属フィンガーペプチドの創製
- Principal Investigator
  
  SUGIURA Yukio
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Chemical pharmacy
- Research Institution
  Kyoto University
Efficient translocation of hybrid peptides through cell membrane for the control of transcriptionPrincipal Investigator
- Principal Investigator
  
  FUTAKI Shiroh
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYOTO UNIVERSITY
Hormonal regulation of production and activation of immunoglobulin binding factor.
- Principal Investigator
  
  KAMADA Masaharu
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokushima
難溶性薬物のキャリアーを目指した大環状ヘリ-クス蛋白質の創製Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokushima
新しい蛋白質モデル構築法を用いたナトリウムチャネル機能の解明Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  The University of Tokushima
チャネル拮抗薬の新規スクリーニング系開発を目指したカルシウムチャネルモデルの構築Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  The University of Tokushima
ペプチドユニットのアセンブリングによる新しい蛋白質モデル構築法の開発Principal Investigator
- Principal Investigator
  
  二木史朗
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokushima
Activation and function of immunoglobulin binding factor in human seminal plasma.
- Principal Investigator
  
  KAMADA Masaharu
- Project Period (FY)
  1994 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokushima, School of Medicine
蛋白質機能解明を志向した新しい人工蛋白質構造体の構築法の開発Principal Investigator
- Principal Investigator
  
  二木史郎
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Bioorganic chemistry
- Research Institution
  The University of Tokushima
Purification and characterization of immunoglobulin binding factor in human seminal plasma
- Principal Investigator
  
  KAMADA Masaharu
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokushima, School of Medicine

All 2019 2018 2017 2016 2015 2014 2013 2012 2009 2008 2007 2005 Other

All Journal Article Presentation Book Patent

[Book] Peptide Science 20152016
- Author(s)
  Tomo Murayama, Shiroh Futaki
- Total Pages
  2
- Publisher
  The Japanese Peptide Society
- Data Source
  KAKENHI-PUBLICLY-26102522
[Book] Peptide Science 20142015
- Author(s)
  Shiroh Futaki, Tomo Murayama, Silvia Pujals, Sayaka Katayama, Hisaaki Hirose, Hiroki Miyamae, and Ikuhiko Nakase
- Total Pages
  2
- Publisher
  The Japanese Peptide Society
- Data Source
  KAKENHI-PUBLICLY-26102522
[Book] Construction of a calcium-gated artificial channel by fusing alamethicin with a calmodulin sensor proteinPeptide Science 20122013
- Author(s)
  Daisuke Noshiro, Kazuhiro Sonomura, Hao-Hsin Yu, Miki Imanishi, Koji Asami, Shiroh Futaki
- Publisher
  The Japanese PeptideSociety, Mino
- Data Source
  KAKENHI-PROJECT-23651216
[Journal Article] Dipicolylamine/Metal Complexes that Promote Direct Cell-Membrane Penetration of Octaarginine2019
- Author(s)
  Kawaguchi Yoshimasa,Ise Shoko,Azuma Yusuke,Takeuchi Toshihide,Kawano Kenichi,Le Toan Khanh,Ohkanda Junko,Futaki Shiroh
- Journal Title
  
  Bioconjug Chem.
  
  Volume: 30 Pages: 454-460
- DOI
  10.1021/acs.bioconjchem.8b00691
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04394, KAKENHI-PUBLICLY-18H04403
[Journal Article] Inducible Membrane Permeabilization by Attenuated Lytic Peptides: A New Concept for Accessing Cell Iinteriors through Ruffled Membranes2019
- Author(s)
  Misao Akishiba, Shiroh Futaki
- Journal Title
  
  Mol. Pharm.
  
  Volume: 16
- DOI
  10.1021/acs.molpharmaceut.9b00156
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Journal Article] Modular Redesign of a Cationic Lytic Peptide to Promote the Endosomal Escape of Biomacromolecules2018
- Author(s)
  Yusuke Azuma, Haruka Imai, Yoshimasa Kawaguchi, Ikuhiko Nakase, Hiroshi Kimura, Shiroh Futaki
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 57 Pages: 12771-12774
- DOI
  10.1002/anie.201807534
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04403, KAKENHI-PROJECT-16H02612
[Journal Article] Importance of Net Hydrophobicity in the Cellular Uptake of All-Hydrocarbon Stapled Peptides2018
- Author(s)
  Sakagami Koki、Masuda Toshihiro、Kawano Kenichi、Futaki Shiroh
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Pages: 1332-1340
- DOI
  10.1021/acs.molpharmaceut.7b01130
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Journal Article] Use of Calmodulin EF-Hand Peptides as Ca2+-Switchable Recognition Tags.2017
- Author(s)
  Oku A, Imanishi M, Noshiro D, Murayama T, Takeuchi T, Nakase I, Futaki S.
- Journal Title
  
  Biopolymers-Peptide Science
  
  Volume: in press
- DOI
  10.1002/bip.22937
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H00763, KAKENHI-PROJECT-16H02612, KAKENHI-PROJECT-26713030
[Journal Article] Loosening of Lipid Packing Promotes Oligoarginine Entry into Cells2017
- Author(s)
  Murayama Tomo、Masuda Toshihiro、Afonin Sergii、Kawano Kenichi、Takatani-Nakase Tomoka、Ida Hiroki、Takahashi Yasufumi、Fukuma Takeshi、Ulrich Anne S.、Futaki Shiroh
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 56 Pages: 7644-7647
- DOI
  10.1002/anie.201703578
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00763, KAKENHI-PROJECT-16J02319, KAKENHI-PROJECT-15K07955
[Journal Article] Cytosolic antibody delivery by lipid-sensitive endosomolytic peptides2017
- Author(s)
  Akishiba M, Takeuchi T, Kawaguchi Y, Sakamoto K, Yu HH, Nakase I, Takatani-Nakase T, Madani F, Graslund A, Futaki S.
- Journal Title
  
  Nature Chemistry
  
  Volume: 9 Pages: 751-761
- DOI
  10.1038/nchem.2779
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26713030, KAKENHI-PUBLICLY-16H01145, KAKENHI-PROJECT-15H02497, KAKENHI-PROJECT-16H02612, KAKENHI-PROJECT-16J09206, KAKENHI-PROJECT-15K07955, KAKENHI-PROJECT-17H00856
[Journal Article] Arginine-rich cell-penetrating peptide-modified exosomes for active macropinocytosis induction and efficient intracellular delivery2017
- Author(s)
  Nakase Ikuhiko、Noguchi Kosuke、Aoki Ayako、Takatani-Nakase Tomoka、Fujii Ikuo、Futaki Shiroh
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Pages: 1991-1991
- DOI
  10.1038/s41598-017-02014-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01145, KAKENHI-PROJECT-15H02497, KAKENHI-PROJECT-16H02612, KAKENHI-PROJECT-15K07955, KAKENHI-PROJECT-17H00856
[Journal Article] Vectorization of biomacromolecules into cells using extracellular vesicles with enhanced internalization induced by macropinocytosis2016
- Author(s)
  I. Nakase*, K. Noguchi, I. Fujii, S. Futaki
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 34937-34937
- DOI
  10.1038/srep34937
- NAID
  120006223631
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H02612, KAKENHI-PROJECT-15H02497
[Journal Article] Effect of amino acid substitution in the hydrophobic face of amphiphilic peptides on membrane curvature and perturbation: N-terminal helix derived from adenovirus internal protein VI as a model2016
- Author(s)
  T. Murayama, S. Pujals, H. Hirose, I. Nakase, S. Futaki
- Journal Title
  
  Biopolymers
  
  Volume: 106 Pages: 430-9
- DOI
  10.1002/bip.22797
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102522, KAKENHI-PUBLICLY-16H00763
[Journal Article] Controlling leucine-zipper partner recognition in cells through modifications of a-g interactions2014
- Author(s)
  Azuma Y, Kükenshöner T, Ma G, Yasunaga JI, Imanishi M, Arndt KM, Matsuoka M, and Futaki S
- Journal Title
  
  Chem Commun (Camb)
  
  Volume: 50 Pages: 6364-6367
- DOI
  10.1039/c4cc00555d
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22114003, KAKENHI-PROJECT-25460148, KAKENHI-PROJECT-25560401, KAKENHI-PROJECT-26460554, KAKENHI-PROJECT-221S0001, KAKENHI-PROJECT-25293219
[Journal Article] Construction of a Ca2+-gated Artificial Channel by Fusing Alamethicin with a Calmodulin-derived Extramembrane Segment2013
- Author(s)
  Daisuke Noshiro, Kazuhiro Sonomura, Hao-Hsin Yu, Miki Imanishi, Koji Asami, Shiroh Futaki
- Journal Title
  
  Bioconjug. Chem
  
  Volume: 24(2) Pages: 188-195
- DOI
  10.1021/bc300468x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23651216
[Journal Article] Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas)2009
- Author(s)
  Takayama K, Nakase I, Michiue H, Takeuchi T, Tomizawa K, Matsui H, Futaki S.
- Journal Title
  
  J. Control. Release 138
  
  Pages: 128-133
- NAID
  120002723158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cel penetrating peptide2009
- Author(s)
  Watkins CL, Schmaljohann D, Futaki S, Jones AT
- Journal Title
  
  Biochem J
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide2009
- Author(s)
  Watkins CL, Brennan P, Fegan C, Takayama K, Nakase I, Futaki S, Jones AT.
- Journal Title
  
  J. Control. Release 140
  
  Pages: 237-244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide.2009
- Author(s)
  Watkins CL, Schmaljohann D, Futaki S, Jones AT.
- Journal Title
  
  Biochem. J. 420
  
  Pages: 179-89
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis2009
- Author(s)
  Nakase I, Hirose H, Tanaka G, Tadokoro A, Kobayshi S, Takeuchi T, Futaki S.
- Journal Title
  
  Mol. Ther 17
  
  Pages: 1868-1876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD.2009
- Author(s)
  Watkins CL, Brennan P, Fegan C, Takayama K, Nakase I, Futaki S, Jones AT.
- Journal Title
  
  J. Control. Release 140
  
  Pages: 237-44
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Enhanced intracellular delivery using arginine-rich peptides by the addition of penetration accelerating sequences (Pas).2009
- Author(s)
  Takayama K, Nakase I, Michiue H, Takeuchi T, Tomizawa K, Matsui H, Futaki S.
- Journal Title
  
  J. Control. Release 138
  
  Pages: 128-33
- NAID
  120002723158
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Cell-surface accumulation of flock house virus-derived peptide leads to efficient internalization via macropinocytosis.2009
- Author(s)
  Nakase I, Hirose H, Tanaka G, Tadokoro A, Kobayashi S, Takeuchi T, Futaki S.
- Journal Title
  
  Mol. Ther. 17
  
  Pages: 1868-76
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery2009
- Author(s)
  Takayama K, Tadokoro A, Pujals S, Nakase I, Giralt E, Futaki S.
- Journal Title
  
  Bioconjug Chem 20
  
  Pages: 249-257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Novel system to achieve one-pot modification of cargo molecules with oligoarginine vectors for intracellular delivery.2009
- Author(s)
  Takayama K, Tadokoro A, Pujals S, Nakase I, Giralt E, Futaki S.
- Journal Title
  
  Bioconjug. Chem. 20
  
  Pages: 249-57
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans.2008
- Author(s)
  Kosuge M, Takeuchi T, Nakase I, Jones AT, Futaki S.
- Journal Title
  
  Bioconjug. Chem. 19
  
  Pages: 656-64
- Data Source
  KAKENHI-PROJECT-19209004
[Journal Article] Membrane-permeable arginine-rich peptides and the translocation mechanisms2005
- Author(s)
  Futaki, S.
- Journal Title
  
  Adv.Drug Deliv.Rev. 57(4)
  
  Pages: 547-558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390029
[Journal Article] Membrane-permeable arginine-rich peptides and the translocation mechanisms2005
- Author(s)
  Futaki, S.
- Journal Title
  
  Adv. Drug Deliv. Rev. 57(4)
  
  Pages: 547-558
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390029
[Journal Article] Membrane-permeable arginine-rich peptides and the translocation mechanisms2005
- Author(s)
  Shiroh Futaki
- Journal Title
  
  Adv.Drug Deliv.Rev. 57(4)
  
  Pages: 547-558
- Data Source
  KAKENHI-PROJECT-17390029
[Patent] 細胞質送達ペプチド2017
- Inventor(s)
  二木史朗、坂本健太郎、秋柴美沙穂
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-055508
- Filing Date
  2017-03-22
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Patent] 細胞質送達ペプチド2017
- Inventor(s)
  二木史朗、坂本健太郎、秋柴美沙穂
- Industrial Property Rights Holder
  二木史朗、坂本健太郎、秋柴美沙穂
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-15H02497
[Patent] 細胞質送達ペプチド2015
- Inventor(s)
  二木史朗、秋柴美沙穂、川口祥正、武内敏秀
- Industrial Property Rights Holder
  国立大学法人京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-09-28
- Overseas
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Cytosolic Delivery of Biomacromolecules2018
- Author(s)
  Shiroh Futaki
- Organizer
  15th Chinese International Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Presentation] Structural determinants of membrane curvature inducing peptide2018
- Author(s)
  Nishimura, M.; Masuda, T.; Kawano, K.; Futaki, S.
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04547
[Presentation] Cytosolic delivery of biomacromolecules2018
- Author(s)
  Shiroh Futaki
- Organizer
  2018 International Symposium on Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Peptide-mediated Delivery of Biomacromolecules into Cells2018
- Author(s)
  Shiroh Futaki（
- Organizer
  Frontiers in Delivery of Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Presentation] Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules2018
- Author(s)
  Shiroh Futaki
- Organizer
  8th Peptide Engineering Meeting (PEM8-2018)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Presentation] Peptide to Modulate Membrane Tension: The Effect on Actin Organization, Cell Structure and the Movement2018
- Author(s)
  Masuda, T.; Baba, K.; Murayama, T.; Inagaki, N.; Futaki, S.
- Organizer
  10th International Peptide Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04547
[Presentation] ペプチドを用いた細胞内デリバリー2018
- Author(s)
  二木史朗
- Organizer
  第393回CBI学会講演会「中分子創薬の実現にむけて」
- Invited
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Peptide-mediated Delivery of Biomacromolecules into Cells2018
- Author(s)
  Shiroh Futaki
- Organizer
  22th Korean Peptide Protein Society (KPPS) Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Presentation] Lipid-sensitive amphiphilic peptides for intracellular delivery of biomacromolecules2018
- Author(s)
  Shiroh Futaki
- Organizer
  10th International Peptide Symposium/55th Japanese Peptide Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Presentation] ペプチドを用いた生理活性分子の細胞内送達2018
- Author(s)
  二木史朗
- Organizer
  日本ケミカルバイオロジー学会第13回年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04403
[Presentation] Elucidating structural factors of curvature-inducing peptides2018
- Author(s)
  Mishimura, M.; Pujals, S.; Murayama, T.; Kawano, K.; Futaki, S.
- Organizer
  22nd Korean Peptide and Protein Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04547
[Presentation] Cytosolic delivery of biomacromolecules2018
- Author(s)
  Shiroh Futaki
- Organizer
  2018 International Symposium on Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] ペプチドを用いた細胞膜の構造・物性変換2018
- Author(s)
  二木史朗
- Organizer
  第91回日本生化学会大会シンポジウム「生体膜の形態変化のメカニズム」
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H04547
[Presentation] Cytosolic delivery of biomacromolecules2018
- Author(s)
  Shiroh Futaki
- Organizer
  2018 International Symposium on Chemical Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] Cytosolic Antibody Delivery by Lipid-sensitive Endosomolytic Peptide2018
- Author(s)
  Shiroh Futaki
- Organizer
  IRCCS-JST CREST Joint Symposium “Chemical sciences facing difficult challenges”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] Approach to control cell movement by affecting membrane tension2018
- Author(s)
  Masuda, T.; Murayama, T.; Futaki, S.
- Organizer
  22nd Korean Peptide and Protein Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H04547
[Presentation] 細胞内デリバリーペプチドの膜との相互作用2017
- Author(s)
  二木史朗
- Organizer
  17-1 バイオ・高分子研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] 膜張力の変化を介して細胞運動を誘起する新規ツールの開発2017
- Author(s)
  益田俊博、村山知、二木史朗
- Organizer
  日本薬学会１３７年会
- Place of Presentation
  仙台市
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] ペプチドを用いた細胞内デリバリー2017
- Author(s)
  二木史朗
- Organizer
  第3回新学術領域研究「中分子戦略」若手シンポジウム
- Place of Presentation
  京都市
- Year and Date
  2017-03-07
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] Peptide-mediated Delivery of Biomacromolecules into Cells2017
- Author(s)
  Shiroh Futaki
- Organizer
  12th Australian Peptide Conference 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] Cytosolic antibody delivery by lipid-sensitive endosomelytic peptide2017
- Author(s)
  Shiroh Futaki
- Organizer
  The Second A3 Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Cytosolic antibody delivery by lipid-sensitive endosomelytic peptide2017
- Author(s)
  Shiroh Futaki
- Organizer
  The Second A3 Roundtable Meeting on Chemical Probe Research Hub
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] 細胞内デリバリーペプチドの膜との相互作用2017
- Author(s)
  二木史朗
- Organizer
  17-1 バイオ・高分子研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] 細胞内デリバリーペプチドの膜との相互作用2017
- Author(s)
  二木史朗
- Organizer
  17-1 バイオ・高分子研究会
- Invited
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Peptide-mediated Delivery of Biomacromolecules into Cells2017
- Author(s)
  Shiroh Futaki
- Organizer
  12th Australian Peptide Conference 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] 見る・知る・作る：ペプチドと細胞膜との相互作用2016
- Author(s)
  二木史朗
- Organizer
  第９回東京大学化学生命工学専攻ChemBioハイブリッドレクチャー
- Invited
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] ペプチドを用いた細胞内デリバリー2016
- Author(s)
  二木史朗
- Organizer
  第22回ペプチドフォーラム
- Place of Presentation
  金沢大学
- Year and Date
  2016-03-05
- Invited
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] 見る・知る・作る：ペプチドと細胞膜との相互作用2016
- Author(s)
  二木史朗
- Organizer
  第９回東京大学化学生命工学専攻ChemBioハイブリッドレクチャー
- Place of Presentation
  東京都
- Year and Date
  2016-10-08
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] ペプチドを用いた細胞内デリバリー2016
- Author(s)
  二木史朗
- Organizer
  創薬懇話会2016 in蓼科：次世代を担う若手のためのメディシナルケミストリーフォーラム
- Place of Presentation
  茅野市
- Year and Date
  2016-07-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] Novel Lysosomolytic Peptides to Achieve Cytoplasmic Distribution of Biomacromolecules2016
- Author(s)
  Shiroh Futaki, Misao Akishiba, Toshihide Takeuchi, Yoshimasa Kawaguchi
- Organizer
  The 16th Akabori Conference: Japanese-German Symposium On Peptide Science
- Place of Presentation
  神戸市
- Year and Date
  2016-05-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] Facilitated membrane translocation of arginine-rich peptides in the presence of curvature inducing peptides2016
- Author(s)
  Shiroh Futaki
- Organizer
  14th Chinese International Peptide Symposium & 5th Asia-pacific International Peptide Symposium (CPS-14 & APIPS-5) APIPS
- Place of Presentation
  南京、中国
- Year and Date
  2016-07-07
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] Membrane-remodeling Amphypathic Helical Peptides Accelerate Direct Penetration of Octaarginine2016
- Author(s)
  Shiroh Futaki, Tomo Murayama
- Organizer
  20th Korea Peptide Protein Society (KPPS) Symposium
- Place of Presentation
  Yangyang, Korea
- Year and Date
  2016-06-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] Novel peptide tool to induce cell movement by affecting membrane tension2016
- Author(s)
  Masada T, Murayama T, Futaki S
- Organizer
  日本ペプチド学会第53回ペプチド討論会
- Place of Presentation
  京都市
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] ペプチドを用いた細胞内デリバリー2016
- Author(s)
  二木史朗
- Organizer
  創薬懇話会2016 in蓼科：次世代を担う若手のためのメディシナルケミストリーフォーラム
- Place of Presentation
  茅野市
- Year and Date
  2016-07-01
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H00763
[Presentation] Peptide Mediated Delivery of Bioactive Proteins into Cells2016
- Author(s)
  Shiroh Futaki
- Organizer
  8th AsiaTIDES
- Place of Presentation
  京都
- Year and Date
  2016-02-24
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Facilitated membrane translocation of arginine-rich peptides in the presence of curvature inducing peptides2016
- Author(s)
  Shiroh Futaki
- Organizer
  14th Chinese International Peptide Symposium & 5th Asia-pacific International Peptide Symposium (CPS-14 & APIPS-5)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] ペプチドの膜との相互作用・膜透過2016
- Author(s)
  二木史朗
- Organizer
  遺伝子・デリバリー研究会　第16回夏期セミナー
- Place of Presentation
  長崎市
- Year and Date
  2016-09-13
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01145
[Presentation] Converting a cytotoxic, hemolytic peptide to an intracellular delivery tool of bioactive proteins2015
- Author(s)
  Shiroh Futaki
- Organizer
  NEA & ASIAHORCs Joint Symposium on Chemical Biology
- Place of Presentation
  OIST
- Year and Date
  2015-11-10
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Membrane curvature and the translocation of arginine-rich cell-penetrating peptides2015
- Author(s)
  Shiroh Futaki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015)
- Place of Presentation
  シェラトンワイキキ
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] Membrane-remodeling Amphipathic Helical Peptides Accelerate Direct Penetration of Octaarginine (R8)2015
- Author(s)
  Tomo Murayama, Shiroh Futaki
- Organizer
  第52回ペプチド討論会
- Place of Presentation
  平塚中央公民館
- Year and Date
  2015-11-16
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] eptide-based approaches for delivering exogenous molecules into cells2015
- Author(s)
  Shiroh Futaki
- Organizer
  International symposium: "From cell-penetrating peptides to nanoparticles for cellular delivery"
- Place of Presentation
  パリ第６大学
- Year and Date
  2015-07-03
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] Peptide mediated delivery of bioactive proteins into cells2015
- Author(s)
  Shiroh Futaki
- Organizer
  The 7th International Peptide Symposium
- Place of Presentation
  Singapore
- Year and Date
  2015-12-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] A novel lysosomolytic peptide designed from spider venom2015
- Author(s)
  Shiroh Futaki
- Organizer
  7th Peptide Engineering Meeting (PEM7-2015)
- Place of Presentation
  Pune, India
- Year and Date
  2015-12-06
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] Exploiting hemolytic amphiphilic peptides as a design template for cytosolic antibody2015
- Author(s)
  Shiroh Futaki
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015)
- Place of Presentation
  Honolulu, Hawaii, USA
- Year and Date
  2015-12-17
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H02497
[Presentation] 曲率誘導性をもつ両親媒性ヘリックスペプチドによるオクタアルギニンの膜透過促進2015
- Author(s)
  村山知、二木史朗
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本大学薬学部
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] カルモジュリンCドメインを用いたカルシウム感受性人工イオンチャネルの創製2012
- Author(s)
  能代大輔、園村和弘、浅見耕司、二木史朗
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌市
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23651216
[Presentation] 細胞内安定型ユビキチン多量体の構築のための新しいアプローチ2012
- Author(s)
  奥彰彦、游晧欣、中瀬生彦、二木史朗
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学、札幌市
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23651216
[Presentation] Peptide tools for controlling and analyzing cell functions2012
- Author(s)
  FUTAKI, Shiroh
- Organizer
  3rd International Symposium on Center for Creation of Functional Materials
- Place of Presentation
  筑波大学、つくば市
- Invited
- Data Source
  KAKENHI-PROJECT-23651216
[Presentation] Peptide tools for controlling and analyzing cell functions2012
- Author(s)
  Shiroh Futaki
- Organizer
  3rd International Symposium on Center for Creation of Functional Materials
- Place of Presentation
  筑波大学、つくば市(招待講演)
- Year and Date
  2012-12-10
- Data Source
  KAKENHI-PROJECT-23651216
[Presentation] 細胞内安定型ユビキチン多量体の構築のための新しいアプローチ2012
- Author(s)
  奥彰彦、游晧欣、中瀬生彦、二木史朗
- Organizer
  日本薬学会　第132年会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23651216
[Presentation] カルモジュリンＣドメインを用いたカルシウム感受性人工イオンチャネルの創製2012
- Author(s)
  能代大輔、園村和弘、浅見耕司、二木史朗
- Organizer
  日本薬学会　第132年会
- Place of Presentation
  北海道大学
- Data Source
  KAKENHI-PROJECT-23651216
[Presentation] アルギニンペプチドを用いた蛋白質の細胞内導入2009
- Author(s)
  二木史朗
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  大阪大学
- Year and Date
  2009-07-09
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Cellular dynamics involved in the internalization of arginine-rich cell penetrating peptides2009
- Author(s)
  Futaki S.
- Organizer
  3rd Asia-Pacific International Peptide Symposium
- Place of Presentation
  Jeju, Korea
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides2009
- Author(s)
  Futaki S.
- Organizer
  PepVec2009 Meeting on "Intracellular Delivery of Therapeutic Molecules: From Bench to Bedside"
- Place of Presentation
  Montpellier, France
- Year and Date
  2009-09-01
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] アルギニンペプチドと細胞膜との相互作用2009
- Author(s)
  二木史朗
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-22
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides2009
- Author(s)
  Shiroh Futaki
- Organizer
  Fifth Peptide Engineering Meeting (PEM5)
- Place of Presentation
  Barchlona, Spain
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides2009
- Author(s)
  Shiroh Futaki
- Organizer
  PepVec2009 Meeting on "Intracellular Delivery of Therapeutic Molecules : From Bench to Bedside"
- Place of Presentation
  Montpellier, France
- Year and Date
  2009-09-01
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Chemical and Biological Factors that Affect the Internalization of Arginine-Rich Cell-Penetrating Peptides2009
- Author(s)
  Futaki S.
- Organizer
  Fifth Peptide Engineering Meeting (PEM5)
- Place of Presentation
  Barcelona, Spain
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] アルギニンペプチドの細胞膜透過2008
- Author(s)
  二木史朗
- Organizer
  日本薬学会第128年会
- Place of Presentation
  横浜国際会議場
- Year and Date
  2008-03-26
- Data Source
  KAKENHI-PROJECT-19021025
[Presentation] .Arginine-rich peptides as a vector of intracellular delivery (Invited lecture)2008
- Author(s)
  Futaki S
- Organizer
  3rd International Workshop on Approaches to Single-Cell Analysis
- Place of Presentation
  ETH Zurich, Switzerland
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19021025
[Presentation] Cellular dynamics of cell penetrating peptides2008
- Author(s)
  Futaki S.
- Organizer
  2nd International Symposium "Cellular Delivery of Therapeutic Macromolecules 2008"
- Place of Presentation
  Cardiff, UK
- Year and Date
  2008-06-24
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] アルギニンペプチドの細胞内移行のダイナミクス2008
- Author(s)
  二木史朗
- Organizer
  第14回日本遺伝子治療学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Arginine-rich peptides as a vector of intracellular delivery2008
- Author(s)
  Futaki S.
- Organizer
  3rd International Workshop on Approaches to Single-Cell Analysis
- Place of Presentation
  Zurich, Switzerland
- Year and Date
  2008-09-12
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] Arginine-rich peptides and their internalization mechanisms2007
- Author(s)
  Futaki S.
- Organizer
  Biochemical Society Focused Meeting
- Place of Presentation
  Telford, UK
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-19209004
[Presentation] 曲率誘導によるアルギニンペプチドの膜透過促進
- Author(s)
  二木史朗、村山知、Silvia Pujals、宮前皓樹、片山沙綾香、中瀬生彦
- Organizer
  第36回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  徳島大学
- Year and Date
  2014-11-20 – 2014-11-21
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] MEMBRANE TRANSLOCATION OF ARGININE-RICH PEPTIDES AND THE EFFECT OF MEMBRANE CURVATURE
- Author(s)
  Shiroh Futaki, Tomo Murayama, Silvia Pujals, Sayaka Katayama, Hisaaki Hirose, Hiroki Miyamae, and Ikuhiko Nakase
- Organizer
  第51回ペプチド討論会
- Place of Presentation
  徳島大学
- Year and Date
  2014-10-22 – 2014-10-24
- Data Source
  KAKENHI-PUBLICLY-26102522
[Presentation] コイルドコイルa-g相互作用に着目したHTLV-1 bZIP factor (HBZ) 結合ペプチドの創出
- Author(s)
  二木史朗、東佑翼、Tim Kukenshoner、Guangyong Ma、安永純一朗、今西未来、丸野孝浩、小林祐次、Katja M. Arndt、松岡雅雄
- Organizer
  日本ケミカルバイオロジー学会
- Place of Presentation
  大阪大学豊中キャンパス
- Year and Date
  2015-06-10 – 2015-06-12
- Data Source
  KAKENHI-PROJECT-25560401

1. SUGIURA Yukio (40025698)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. NAGAOKA Makoto (60314275)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. NAKASE Ikuhiko (40432322)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
4. KAMADA Masaharu (60145018)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. MATSUOKA Masao (10244138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. KIDO Hiroshi (50144978)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. GOTOH Susumu (40263149)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IMANISHI Miki (80362391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TAKEUCHI Toshihide (70600120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. KAWANO Kenichi (70732874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中屋豊 (50136222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 吉村徹 (70182821)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 松尾道憲 (00335308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 森山龍一 (60191061)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 河田光博 (60112512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松田賢一 (40315932)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 岩井一宏 (60252459)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大神田淳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 中瀬朋夏

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. 安永純一朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Futaki Shiroh 二木 史朗

FUTAKI Shiroh 二木 史朗

二木 史郎 フタキ シロウ

FUTAKI Siroh 二木 史郎

Research Projects

Research Products

Co-Researchers

生体膜の曲率・脂質パッキング状態変化を誘起する機能性ペプチドと展開Principal InvestigatorOngoing

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生理活性タンパク質の細胞内移送の新機軸Principal InvestigatorOngoing

Principal Investigator

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生物機能中分子の細胞導入の分子基盤Principal InvestigatorOngoing

Principal Investigator

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生体膜の曲率・脂質パッキング状態変化を誘起する機能性ペプチドPrincipal InvestigatorOngoing

Principal Investigator

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Research Institution

ケモテクノロジーを利用したユビキチン鎖の機能解析と制御Ongoing

Principal Investigator

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Research Institution

生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツールPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

生物機能中分子の細胞内への新規導入基盤の創出Principal Investigator

Principal Investigator

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Review Section

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Creation of artificial lligand-sensitive ion-channel using nucleic acid aptamer for extracellular segmentPrincipal Investigator

Principal Investigator

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New strategy for intracellular delivery of biomacropharmaceuticalsPrincipal Investigator

Principal Investigator

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生体膜における曲率形成と膜の形態変化を誘導・制御するペプチドツールPrincipal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Library design and selection for obtaining peptides that target HTLV-1 proteinPrincipal Investigator

Principal Investigator

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Development and application of novel calcium-sensitive protein splicing systemsPrincipal Investigator

Principal Investigator

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細胞内可視化・ハイスループット検出系創出のための効率的細胞導入法Principal Investigator

Principal Investigator

Project Period (FY)

Futaki Shiroh 二木史朗

FUTAKI Shiroh 二木史朗

二木史郎フタキシロウ

FUTAKI Siroh 二木史郎