HIRAMATSU Osamu 平松修

Researcher Number	50208849
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Affiliation (based on the past Project Information) *help	2007 – 2013: 川崎医療福祉大学, 医療技術学部, 准教授 1999 – 2005: Kawasaki College of Allied Health Professions, Dept. of Applied Medical Engineering, Assistant Professor, 臨床工学科, 講師 1997 – 1998: Kawasaki College of Allied Health Professions, Medical Engineering, Assistant Pr, 医用電子技術科, 講師 1992 – 1996: 川崎医療短期大学, 医用電子技術科, 助手
Review Section/Research Field	Principal Investigator Circulatory organs internal medicine / Biomedical engineering/Biological material science Except Principal Investigator Circulatory organs internal medicine / Biomedical engineering/Biological material science / Biomedical engineering/Biological material science / 生物・生体工学 / 計測・制御工学
Keywords	Principal Investigator Arteriole / 細動脈 / Flow visualization / CCD microscope / Cardiac lymphatics / 微小冠循環 / ニトログリセリン / Venule / Microcirculation / 微小循環 … More / 細静脈 / 冠微小循環 / CCD生体顕微鏡 / リンパ流速 / high speed CCD生体顕微鏡 / 心臓リンパ管 / Caediac lymphtic / Coronary microcirculation / Nitroglycerin / High speed CCD microscope / ハイスピードCCD生体顕微鏡 / CCD-microscope / ニードル型CCD生体顕微鏡 / CCD-Microscope / 冠循環 … More Except Principal Investigator superoxide / nitric oxide (NO) / 一酸化窒素(NO) / 微小循環 / asymmetric dimethylarginine (ADMA) / L-arginine / センサー / スーパーオキサイド / superoxide dismutase (SOD) / myocardial ischemia / 心筋虚血 / 内皮細胞 / oxidized LDL / tetrahydrobiopterin (BH_4) / oxidative stress / hemodialysis / ADMA / 高血圧 / 血液汚染 / asymmetric dimethylarginine(ADMA) / テトラハイドロビオプテリン(BH_4) / 酸化LDL / tetrahdrobiopterin (BH_4) / 酸化ストレス / 血液透析 / Impedance measurement / Endothelial cellular gaps / Endothelial cells / Nano-mechanics / 電気インピーダンス / 細胞間際 / 実時間解析 / 細胞間隙 / ずり応力 / 培養内皮細胞 / 電気インピーダンス計測 / endothelial function / catheter / sensor / in vivo計測 / 冠状静脈洞 / 酸化窒素(NO) / 血管内皮機能 / カテーテル / センサ / Velocity mapping / glomerular microcirculation / CCD Microscope / 光マーカー / 血流動態 / 腎微小循環 / 高速度CCD生体顕微鏡 / 糸球体毛細管 / 速度マッピング / 糸球体内微小循環 / ペンシルレンズ / CCD生体顕微鏡 / microcirculation / vascular response / myogenic regulation / pulse pressure / mechanical stress / arteriole / subendocardium / 血管反応 / 筋原性調節 / 拍動圧 / メカニカルストレス / 細動脈 / 心内膜側 / systemic NO production rate / coronary circulation control / fluorescent indicator / tetrahydrobiopterin / NO sensor / canine femoral artery / 微小電極 / ニトログリセリン / ラット腸間膜小動脈 / NADH / 蛍光計測 / 潅流量 / ラット摘出心 / 硝酸イオン / 生体内総NO産生速度 / 冠灌流調節 / 蛍光指示薬 / テトラヒドロビオプテリン / NOセンサー / イヌ大腿動脈 / microregional ischemia / molecular flow tracer / local homogeneity / global heterogeneity / myocardial blood flow / デスメチルイミプラン / 微小循環障害 / 分子血流トレーサ / 局所一様性 / 全体不均一性 / 心筋内血流 / microflow-imaging / heterogeneity / RI molecular tracer / intramyocardial flow distribution / microcirculatory regulation / R1分子血流トレーサ / 不均一性 / 血流マイクロイメージング / RI分子血流トレーサ / 心筋内血流分布 / 微小循環調節 / FITC-dextran / Indocyanine green / Microcirculation / Subendocardial vessels / Beating heart / Needle-probe video-microscope with a CCD camera / FITCデキストラン / インドシアニングリーン / 心内膜側血管 / 拍動心 / CCDマイクロスコープ / 電子顕微鏡 / レーザースキャン顕微鏡 / 血管鋳型 / 血流速度 / 冠動脈 / 還元反応 / 還元物質 / 抗酸化力 / カテキン / ポリフェノール / 抗酸化物質 / 亜硝酸 / 硝酸 / 一酸化窒素（NO） / ナノメディスン / ナノバイオロジー / アクチンフィラメト / 動脈硬化 / ナノバイオロジー・ナノメディスン / 情報伝達 / 白血球 / ミオシン / アクチン / アクチン・ミオシン架橋 / SPring-8 / 冠微小循環 / フィジオーム / 僧帽弁逆流 / 弁輪 / 僧帽弁 / リアルタイム3D超音波断層法 / リアルタイムグラメトリシステム / 冠循環 / 貫通枝血管 / 心筋微小血管造影 Less

Evaluation of generation process and physiological functional mechanism of nitrate-derived nitric oxide in the vascular system
- Principal Investigator
  
  MOCHIZUKI Seiichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki University of Medical Welfare
Real time and in situ observation of actin structure in migrating leukocyte
- Principal Investigator
  
  KATAOKA Noriyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki University of Medical Welfare
Promotion of cardiovascular physiome focusing on coronary microcirculation and myocardial crossbridge dynamics
- Principal Investigator
  
  KAJIYA Fumihiko
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki University of Medical Welfare
  Kawasaki College of Allied Health Professions
リアルタイム3D超音波断層法による僧帽弁輪立体構造の計測と弁逆流発生機序の解析
- Principal Investigator
  
  OGASAWARA Yasuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School
リアルタイムグラメトリシステムの開発と8GeV放射光心筋微小血管造影への応用
- Principal Investigator
  
  TACHIBANA Hiroyuki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Development of an in vivo real-time measurement system of nitric oxide and superoxide and their clinical applications
- Principal Investigator
  
  MOCHIZUKI Seiichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Kawasaki College of Allied Health Professions
Development of In Vivo Vascular Endothelial Cellular Nano-mechanics Measurement System
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Analysis of cardiac lymphatic dynamics in beating canine hearts using a high-speed CCD microscopePrincipal Investigator
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki Medical College of Allied Health Professions
Evaluation of dynamic changes of nitric oxide and oxidative stress in hemodialysis patients
- Principal Investigator
  
  MOCHIZUKI Seiichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
Development of Pencil-type CCD Microscope for evaluating of renal glomerular microcirculation with normal and hypertensive Rat
- Principal Investigator
  
  TACHIBANA Hiroyuki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Evaluation of the interaction between myogenic response and endothelium-derived factor by a microvessel perfusion system
- Principal Investigator
  
  MOCHIZUKI Seiichi
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  生物・生体工学
- Research Institution
  Kawasaki College of Allied Health Professions
Endothelium-dependent and -independent responses of coronary arteriole to pulsatile mechanical stress in vivo
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Three-dimensional imaging of myocardial blood flow with microcomputed
- Principal Investigator
  
  JIKUYA Kazuaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  計測・制御工学
- Research Institution
  Kawasaki College of Allied Health Professions
Analysis of vasodilated effect of nitroglycerin on microvessels us ing a high speed CCD microscopePrincipal Investigator
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasnki College of Allied Health Professions
Development of 3-D Evaluation System of Microheterogeneity of Intramyocardial Flow Using Molecular Flow Tracers
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Analysis of vasodilated effect of nitroglycerin on microvesselsPrincipal Investigator
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Developement of side-on typed needle-probe for CCD microscopePrincipal Investigator
- Principal Investigator
  
  HIRAMATSU Osamu
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki College of Allied Health Professions
血管内皮配列と微細形態観察のための冠血管鋳型・レーザースキャン顕微鏡解析法の開発
- Principal Investigator
  
  後藤真己 (後藤真巳)
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College of Allied Health Professions
Study on the subendocardial ischemia using a high resolution needle-probe video-microscope with a CCD camera
- Principal Investigator
  
  GOTO Masami
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Kawasaki College Of Allied Health Professions

All 2012 2007 2006 2005

All Journal Article Presentation

[Journal Article] Important role of endogenous hydrogen peroxide in pacing-induced metabolic coronary vasodilation in dogs in vivo2007
- Author(s)
  Yada T, Shimokawa H, Hiramatsu O, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F
- Journal Title
  
  J Am Coll Cardiol. 50(13)
  
  Pages: 1272-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Cardioprotective Role of Endogenous Hydrogen Peroxide during Ischemia-Reperfusion Injury in Canine Coronary Microcirculation in Vivo2006
- Author(s)
  Yada T, Shimokawa H, Hiramatsu O, Haruna Y, Morita Y, Kashihara N, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F
- Journal Title
  
  Am J Physiol Heart Circ Physiol 291(3)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo.2006
- Author(s)
  Yada T, Shimokawa H, Hiramatsu O, Haruna Y, Morita Y, Kashihara N, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 291・3
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Beneficial effect of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia/reperfusion injury in canine coronary microcirculation in vivo.2005
- Author(s)
  Yada T, Shimokawa H, Hiramatsu O, Kajiya T, Shigeto F, Tanaka E, Shinozaki Y, Mori H, Kiyooka T, Katsura M, Ohkuma S, Goto M, Ogasawara Y, Kajiya F.
- Journal Title
  
  Am Coll Cardiol. 45・4
  
  Pages: 599-607
- Data Source
  KAKENHI-PROJECT-17200033
[Journal Article] Direct measurement of nipradilol-derived nitric oxide in the vascular wall of canine femoral arteries.2005
- Author(s)
  Mochizuki S, Chiba Y, Hiramatsu O, Tachibana H, Nakamoto H, Toyota E, Ogasawara Y, Kajiya F.
- Journal Title
  
  Heart Vessels. 20・4
  
  Pages: 175-178
- Data Source
  KAKENHI-PROJECT-17200033
[Presentation] 生体内NO2 -からのNO 生成反応の基礎的検討2012
- Author(s)
  望月精一, 小川武人, 仲本博, 平松修, 小野淳一
- Organizer
  第8回医療福祉研究報告会
- Place of Presentation
  川崎医療福祉大学(岡山県倉敷市)
- Year and Date
  2012-02-28
- Data Source
  KAKENHI-PROJECT-23500534
[Presentation] Cardioprotective Role of Hydrogen Peoxide as an Endogenous EDHF during Ischemia-reperfusion Injury in Canine Coronary Microvessels in Vivo2006
- Author(s)
  Yada T, Shimokawa H, Hiramatsu O, Shinozaki Y, Mori H, Goto M, Ogasawara Y, Kajiya F
- Organizer
  The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society
- Place of Presentation
  Nagoya
- Data Source
  KAKENHI-PROJECT-17200033

1. GOTO Masami (50148699)

# of Collaborated Projects: 15 results

# of Collaborated Products: 5 results
2. MOCHIZUKI Seiichi (60259596)

# of Collaborated Projects: 14 results

# of Collaborated Products: 2 results
3. TACHIBANA Hiroyuki (00241216)

# of Collaborated Projects: 13 results

# of Collaborated Products: 1 results
4. MATSUMOTO Takeshi (30249560)

# of Collaborated Projects: 13 results

# of Collaborated Products: 0 results
5. KAJIYA Fumihiko (70029114)

# of Collaborated Projects: 11 results

# of Collaborated Products: 6 results
6. OGASAWARA Yasuo (10152365)

# of Collaborated Projects: 9 results

# of Collaborated Products: 6 results
7. KATAOKA Noriyuki (20250681)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
8. TSUJIOKA Katsuhiko (30163801)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
9. YADA Toyotaka (00210279)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. YAGI Naoto (80133940)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. SUGIURA Seiryo (10272551)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. HIMENO Ryutaro (60342838)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. SUGA Hiroyuki (90014117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. SHIMIZU Juichiro (80294403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MOHRI Satoshi (00294413)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
16. NAKAMURA Kazufumi (10335630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NINOMIYA Yoshifumi (70126241)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. KOBAYASHI Naoya (10325102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. HASHIMOTO Ken (80341080)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. ONO Junichi (50435351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. OGAWA Takehito (10454050)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. JIKUYA Kazuaki (90206350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YOSHIDA Kiyoshi (60322583)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. MIYASAKA Takehiro (60308195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. KASHIHARA Naoki (10233701)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. KIMOTO Masumi (40108866)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 仲本博 (10299183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 渡邉望 (60319960)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. SIPKEMA Pieter

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HIRAMATSU Osamu 平松 修

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Analysis of cardiac lymphatic dynamics in beating canine hearts using a high-speed CCD microscopePrincipal Investigator

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Analysis of vasodilated effect of nitroglycerin on microvessels us ing a high speed CCD microscopePrincipal Investigator

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HIRAMATSU Osamu 平松修