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SUGINO Hiromu  杉野 弘

ORCIDConnect your ORCID iD *help
Researcher Number 50211305
Other IDs
External Links
Affiliation (based on the past Project Information) *help 1997 – 2006: University of Tokushima, The Institute for Enzyme Research, Professor, 分子酵素学研究センター, 教授
2002: 徳島大学, 分子酵素研究センター, 教授
2000: University of Tokushima, The Institute for Enzyme Research, Professor
1998: 徳島大学, 分子酵素学究センター, 教授
1996: 徳島大学, 酵素科学研究所, 教授 … More
1992 – 1996: 徳島大学, 酵素科学研究センター, 教授
1993: 徳島大学, 酸素科学研究センター, 教授
1990 – 1991: 理化学研究所, フロンティア研究システム, 研究員
1989: 理化学研究所, 国際フロンティア研究システム・バイオメディア研究チーム, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Functional biochemistry / 物質生物化学 / Structural biochemistry / Functional biochemistry
Except Principal Investigator
内科学一般 / Digestive surgery / Metabolomics / Endocrinology / Conservative dentistry / Applied genomics / Structural biochemistry
Keywords
Principal Investigator
アクチビン / フォリスタチン / アクチビン受容体 / FLRG / Smad / ホリスタチン / activin / PDZドメイン / follistatin / アポトーシス … More / WWドメイン / ヘパラン硫酸 / 受容体 / ARIP / エンドサイトーシス / heparan sulfate / 神経シナプス / 分化 / 神経細胞 / 神経誘導 / GDF8 / Ser / Dok1 / WW domain / PDZ domain / endocytosis / apoptosis / TGF-β / シグナル伝達 / Heparan sulfate / Mesoderm induction / Activin receptor / Activin / 中胚葉誘導 / PDZ / Dok-1 / β-カテニン / 神経幹細胞 / オ-ガナイザー / 細胞分化 / 胚性腫瘍 / 初期胚 / 中胚葉 / キナーゼ / 結合タンパク質 / PDZタンパク / 肝再生 / 筋ジストロフィー / 筋分化 / 神経分化 / Thr kinase / クロストーク / Thrキナーゼ / PDZ蛋白質 / アォリスタチン / synapse / activin receptor / TSC-36 / organizer / development / 発生 / ヘバラン硫酸 / cell-cycle / growth / differentiation / TGF-beta / 2-ハイブリッドシステム / α-フォドリン / 増殖 / 細胞内情報伝達 / 細胞増殖 / Central nerve system / Neural induction / Follistatin / 中枢神経系 / dual kinase / リン酸化 / Embryo / EC cell / Activin-binding protein / FSH / 硫酸多糖 / 細胞接着性 / 分化誘導 / 結合蛋白質 / EC細胞 / アクチビン結合タンパク質 / 膵島β細胞 / インスリン / 器官形成 / 筋形成 / 歯牙形成 / マイオスタチン / PTEN / ALK7 / フォリスタチンドメイン / TGF-βスーパーファミリー / 胚性腫瘍細胞 / 造血幹細胞 / ツメガエル / XTC / 胚性癌細胞 / ILー1 / シグナル伝達機構 / 顆粒膜細胞 / マクロファ-ジ / 発生・分化 … More
Except Principal Investigator
アクチビン / トランスジェニックマウス / TGF-β / FRP / DBA / Activin / follistatin / HB-EGF / Cdk4 / 1マウス / PCR / ホリスタチン関連蛋白 / Transgenic mouse / Pancreatic islets / 糖尿病 / Reg I / Pax6 / 膵β細胞 / 膵島 / サイトカイン / アポトーシス / フォリスタチン / DNA microarray / fluvastatin / in-chin-co-to / FK506 / liver regeneration / liver transplantation / Massive hepatectomy / activin / cytokine / グラフト機能不全 / 肝再生 / 大量肝切除 / 過小グラフト / 肝移植 / Diabetes mellitus / Regenerative medicine / Pancreatic B cells / p16 / 細胞周期 / Pdx1 / 再生医療 / c-fos / anti-type II collagen antibody / MMP1 / TGF-beta / synovial cells / transgenic mouse / folistatin-related protein / ノックアウトマウス / コラーゲン誘導関節炎 / gp130-RAPS / 慢性関節リウマチ / 1 mouse / FLAG epitope / type II collagen / transgene / transgenic mice / Iマウス / FLAGエピトープタグ / II型コラーゲンプロモーター / 1 マウス / FLAGエピト-プタブ / IL型コラーゲンプロモーター / トランスジーン / Interferon-γ / Pancreatic β cells / Pax-6 / 発生工学 / 腫瘍発生 / インターフェロン-γ / periodontitis / cell-cycle arrest / interleukin-1 receptor antagonist / interleukin-1 / apotosis / スレオニンキナーゼ / セリン / IL-1β変換酵素 / IL-1β / 歯周炎予防 / 歯周炎 / 細胞周期の停止 / インターロイキン-1レセプターアンタゴニスト / インターロイキン-1 / 分化 / ES細胞 / クロマチン / 幹細胞 / プロテオミクス / グリピカン / シンデカン / bFGF / エンドサイトーシス / ヘパラン硫酸プロテオグリカン / ヘパラン硫酸 / プロテオグリカン / ホリスタチン / ミトコンドリア / 極細胞 / 背腹軸 / T遺伝子 / 胚誘導 / 神経分化 / 胚軸形成 / 筋分化 / ビテロジェニン / ビテロゲニン / ミドカイニン / 胴尾部構造 / 内胚葉分化 / 神経誘導 / 遺伝子発現 / 細胞系譜 / 生殖細胞 / ミドカイン / BMP Less
  • Research Projects

    (35 results)
  • Co-Researchers

    (37 People)
  •  幹細胞の未分化性を管理する遺伝情報制御タンパク質群のプロテオーム解析

    • Principal Investigator
      栗崎 晃
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied genomics
    • Research Institution
      The University of Tokushima
  •  The investigation of regulatory mechanism on liver regeneration after massive hepatectomy

    • Principal Investigator
      FUJII Masahiko
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      The University of Tokushima
  •  Ser/Thrキナーゼ型受容体を介するアポトーシスの分子機構Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Intracellular and extracellular control of activin signaling by novel regulatory moleculesPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokushima
  •  アクチビンのシグナル伝達制御と器官形成Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  アクチビンシグナルの制御による内分泌器官形成機構の解析Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  PDZタンパクを介するシグナル伝達のクロストークと発癌Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Regulation Mechanisms for Activin SignalingPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      The University of Tokushima
  •  Suppressive autoantibodies in rheumatoid arthritis : construction of gene-modified animals and analysis of their arthrapathy

    • Principal Investigator
      OZAKI Shoichi
    • Project Period (FY)
      2001 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      内科学一般
    • Research Institution
      St.Marianna University School of Medicine
  •  Analysis of Pancreatic B-Cell Development and an Animal Model of Regeneration Therapy for Diabetes Mellitus Using Transgenic Mice

    • Principal Investigator
      YAMAOKA Takashi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Metabolomics
    • Research Institution
      The University of Tokushima
  •  初期発生におけるアクチビン/フォリスタチン系の役割Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  Ser/Thrキナーゼ型受容体を介する情報伝達系のPDZ蛋白質による制御と発癌Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      2000
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (C)
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  神経誘導におけるアクチビン/フォリスタチン系の役割Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1999
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  follistatin-related protein : analysis of arthritis induced in its transgenic mice

    • Principal Investigator
      OZAKI Shoichi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      内科学一般
    • Research Institution
      KYOTO UNIVERSITY
  •  神経系誘導におけるフォリスタチンファミリーの役割Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      The University of Tokushima
  •  ヘパラン硫酸プロテオグリカンを介した細胞増殖・分化因子の細胞内代謝機構の解析

    • Principal Investigator
      中村 隆範
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      香川医科大学
  •  Roles of activin/follistatin in neural inductionPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Tokushima
  •  Activin signal transduction and its regulation mechanismsPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (B).
    • Research Field
      Functional biochemistry
    • Research Institution
      University of Tokushima
  •  Analysis of Islet Development Using Transgenic Mice

    • Principal Investigator
      YAMAOKA Takashi
    • Project Period (FY)
      1998 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Endocrinology
    • Research Institution
      The University of Tokushima
  •  アフリカツメガエル胚の神経誘導におけるアクチビン-フォリスタチン系の役割Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  Mesoderm and neuron induction and activin signalingPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      Structural biochemistry
    • Research Institution
      University of Tokushima
  •  Development of preventive for periodontitis by using avtivin that indices apoptosis and suppresses the production of IL-1

    • Principal Investigator
      NISHIHARA Tatsuji
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Conservative dentistry
    • Research Institution
      National Institute of Infectious Diseases
  •  Neuronal differentiation and activin signal transductionPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The Institute for Enzyme Research
  •  Activin Signal Transduction in Cell Growth, Differentiation and ApoptosisPrincipal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Functional biochemistry
    • Research Institution
      University of Tokushima
  •  造血幹細胞の分化とアクチビンのシグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  胚性腫瘍細胞におけるアクチビンの増殖・分化シグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  アクチビン情報伝達系におけるホリスタチンの役割Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      The University of Tokushima
  •  胚性腫瘍の成立とアクチビンの情報伝達機構Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  マウス胚性癌細胞におけるアクチビンの増殖・分化シグナル伝達機構の解析Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Cancer Research
    • Research Institution
      The University of Tokushima
  •  形態形成の調節機構-初期発生を制御する分子機構

    • Principal Investigator
      浅島 誠
    • Project Period (FY)
      1993 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokyo
  •  アクチビン-ホリスタチン系による中胚葉誘導制御の分子機構Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      The University of Tokushima
  •  アクチビン-ホリスタチン-プロテオグリカン相互作用による細胞増殖・分化調節機構

    • Principal Investigator
      中村 隆範
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokushima
  •  The role of activin binding protein in the activin signal transduction.Principal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      The University of Tokushima
  •  Signal Transduction Mechanism in differentiation and Development of Follicular Granulosa Cells.Principal Investigator

    • Principal Investigator
      SUGINO Hiromu
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      The Institute of Physical and Chemical Research
  •  生殖腺細胞の発生・分化におけるマクロファ-ジの役割Principal Investigator

    • Principal Investigator
      杉野 弘
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      The Institute of Physical and Chemical Research
  • 1.  NAKAMURA Takanori (70183887)
    # of Collaborated Projects: 17 results
    # of Collaborated Products: 0 results
  • 2.  TSUCHIDA Kunihiro (30281091)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 3.  SHOJI Hiroki (10263873)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 0 results
  • 4.  OGURA Yasunori (60304557)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 5.  KURISAKI Akira (60346616)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  YAMAOKA Takashi (40263826)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NOJI Sumihare (40156211)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  ITAKURA Mitsuo (60134227)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  OZAKI Shoichi (00231233)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  OGAWA Yoshihiro (70291424)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  OHMOTO Yasukazu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 12.  粉川 京子
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 13.  NISHIHARA Tatsuji (80192251)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  OKAHASHI Nobuo (40150180)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TANAKA Masao (10332719)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  YOSHIZAKI Kazuyuki (90144485)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  FUJII Masahiko (20380040)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  IMURA Satoru (90380021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  MORINE Yuji (60398021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  SHIMADA Mitsuo (10216070)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  浅島 誠 (00090564)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  西田 宏記 (60192689)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  安倍 眞一 (90109637)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  村松 喬 (00030891)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  上野 直人 (40221105)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  佐藤 矩行 (30025481)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  岡田 益吉 (60015534)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  山名 清隆 (20037162)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  VAN-DEN Eiinden
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  ETO Yuzuru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  島崎 俊一
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  KOGAWA Kyoko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  EIJNDEN van
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  EIJNDENーVAN ふぁん
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  EIJNDEN-VAN RAAIJ A.J.M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  RAAIJ A.J.M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  EIJINDENーVAN エージェイ
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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