Yamada Toshiyuki 山田俊幸

… Alternative Names

山田俊幸ヤマダトシユキ

YAMADA Toshiyuki 山田俊幸

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Researcher Number	50211636
Other IDs
External Links
Affiliation (Current)	2025: 群馬パース大学, 医療技術学部, 教授
Affiliation (based on the past Project Information) *help	2013 – 2023: 自治医科大学, 医学部, 教授 2008 – 2011: Jichi Medical University, 医学部, 教授 2007: Jichi Medical University, Dept, of Medicine, Associated Professor 2005 – 2006: JMS, School of Medicine, Associate Professor, 医学部, 助教授 2000 – 2004: 順天堂大学, 医学部, 助教授 1996 – 1998: 自治医科大学, 医学部, 講師 1989 – 1990: Niigata Univ. Hospital, Assistant, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Laboratory medicine / Laboratory medicine / Basic Section 52010:General internal medicine-related Except Principal Investigator Laboratory medicine / Laboratory medicine / Collagenous pathology/Allergology / Basic Section 90130:Medical systems-related / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Neurology / Orthopaedic surgery / Medical systems
Keywords	Principal Investigator アミロイドーシス / 血清アミロイドA / 炎症 / inflammation / amyloidosis / 表面プラズモン共鳴 / 単球 / 臨床化学 / マウス / HDL … More / 免疫組織化学 / リコンビナント蛋白 / モノクロナル抗体 / 酸化 / モノクローナル抗体 / モノクロ―ナル抗体 / 参加修飾 / 質量分析 / ヒストン / 酸化修飾 / 断片化ペプチド / immune targeting / knock-in-mouse / mouse model / tracer experiment / monoclonal antibody / apolipoprotein E / イメージング / 診断法 / アポリポ蛋白E / ノックインマウス / トレーサー実験 / イムノターゲッティング / マウスモデル / アポリポプロテインE / glucocorticoid / fibrillogenesis / macrophage / monocyte / serum amyloid A / THP-1 / コルチコステロイド / アミロイド沈着 / サイトカイン / 細胞株 / アミロイド線維 / SAA / フィブレート / 肝細胞 / 線維化 / マクロファージ / 自己抗体 / リポ蛋白 / 分子間相互作用 / 遺伝子組換え体 / ポリモルフィズム / 親和性 / 多型 / 酵素免疫測定法 / アポリポ蛋白AII / アポリポ蛋白AI / 人工透析 / 慢性関節リウマチ / 多発性骨髄腫 / マウス実験アミロイドーシス / エピトープ解析 … More Except Principal Investigator HDL / 血清アミロイドA / SAA / 加齢 / Nonspecific cross-reacting antigen / Carcinoembryonic antigen / 尿 / PPAR α / 血清アミロイドA蛋白 / アミロイドーシス / ALアミロイドーシス / AAアミロイドーシス / 関節リウマチ / 超音波造影剤 / 超音波障害 / ブタ / ウサギ / 肺 / 消化管 / ARFIエラストグラフィ / 音響放射力インパルス(ARFI) / 糖鎖付加 / 脂質代謝 / Hisタグ / アフィニティータグ / アポリポタンパク質 / 血清アミロイドA4 / SAAアイソタイプ / アイソフォーム / アイソタイプ / 腎機能 / 多発性骨髄腫 / 臨床検査医学 / 内科 / サルコイドーシス / ビタミンD / 老化 / FGF23 / 無機リン / 維持血液透析 / 高リン血症 / 慢性腎臓病 / リン過剰 / Calciprotein particle / Enzyme activity / Child / Serum cholesterol / Reference Values / Aging / Lectin affinity electrophoresis / Alkaline phosphatase isoenzyme / 血清蛋白分画 / アルカリホスファターゼ / グリコヘモグロビン / フルクトサミン / 化学検査 / アルカリホスファタ-ゼ / 乳幼児 / 痴呆 / 高齢者 / 血清酵素 / 新生児 / レクチン / 酵素活性 / 小児 / 血清コレステロ-ル / 基準値(正常値) / レクチン親和電気泳動法 / アルカリホスファタ-ゼアイソザイム / Human-mouse heterohybridoma / Tumor associated antigen / Monoclonal antibody / ヒトーマウスヘテロハイブリドーマ / 癌特異抗体 / モノクローナル抗体 / isoprotein / 糖鎖抗原 / ヒト-マウスヘテロハイブリドーマ / Non specific cross-reacting antigen / ヒト-マウスヘテロハイブリド-マ / 腫瘍関連抗原 / モノクロ-ナル抗体 / Immunounreactive albumin / Protein 1 / Pepsin / α1-microglobulin / β2-microglobulin / Protease / Stability / Urine / 不安定性 / α-1ミクログロブリン / 修飾アルブミン / 親水性 / 疎水性 / 非特異的吸着 / 尿中安定性 / シスタチンC / immunounreactive albumin / プロテイン1 / ペプシン / α1-ミクログロブリン / β2-ミクログロブリン / 蛋白分解酵素 / 安定性 / Apolipoprotein E / Cerebrospinal fluid / Lipoprotein / Inflammation / Alzheimer's dementia / アルツハイマー型痴呆 / アポE / 髄液 / リポ蛋白 / 炎症 / アルツハイマー型認知症 / Fibrate / Reactive Amyloidsis / PPARα / フィブラート / 2次性アミロイドーシス / 尿沈渣 / 腎障害 / Rheumatoid arthritis / Amyloidosis / 細胞接着因子 / 血管内皮細胞 / 細胞接着分子 / 超音波 Less

The Effect of Acoustic Radiation Force Impulse on Gastrointestinal Tract and Tissues Enhanced with Ultrasound Contrast Agent in Large Animals: An Investigation of Its Clinical Use
- Principal Investigator
  
  高山法也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Jichi Medical University
Understanding of the fundamental properties of serum amyloid A4 to elucidate its physiological and pathological significance
- Principal Investigator
  
  Tanaka Masafumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kobe Pharmaceutical University
急性期蛋白SAAの分子修飾と炎症ベクトルの研究Principal Investigator
- Principal Investigator
  
  山田俊幸
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Jichi Medical University
Mechanisms of AA amyloid polymerization and tissue deposition
- Principal Investigator
  
  Kuroda Takeshi
- Project Period (FY)
  2017 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Niigata University
Clinical significance of blood calciprotein particle in chronic kidney disease
- Principal Investigator
  
  Iwazu Yoshitaka
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Jichi Medical University
A diagnosis method of the reactive amyloidosis by urinary SAA fragment measurement and determination of the effect of treatment
- Principal Investigator
  
  Kuroda Takeshi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Niigata University
Detection of low affinity autoantibodies like anti-amyloid antibodies by surface plasmon resonance analysis Detection of low affinity autoantibodies like anti-amyloid antibodies by surface plasmon resonance analysisPrincipal Investigator
- Principal Investigator
  
  YAMADA Toshiyuki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Jichi Medical University
Effect of sonocation for the expression of the adhesion molecules in the HUVEC
- Principal Investigator
  
  FUJII Yasutomo
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Jichi Medical University
Functional analysis for serum amyloid A polymorphismPrincipal Investigator
- Principal Investigator
  
  YAMADA Toshiyuki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Jichi Medical University
Elucidation of heterogeneity of urine proteins as fundamentals for analyses of pathophysiology
- Principal Investigator
  
  ITOH Yoshihisa
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Asahikawa Medical College
The role of inflammation on development of Alzheimer's dementia
- Principal Investigator
  
  MIIDA Takashi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Niigata University
Immune targeting of apolipoprotein E in amyloid deposits ; a fundamental study using murine modelPrincipal Investigator
- Principal Investigator
  
  YAMADA Toshiyuki
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  JICHI MEDICAL SCHOOL
  Juntendo University
Regulation of Reactive Amyloidosis via Activation of Peroxisome Proliferator Activated Receptor α
- Principal Investigator
  
  OGOSE Akira, 羽生忠正
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY
Synthesis, metabolism andfibrillogenesis of serum amyloid A bymonocytes or macrophagesPrincipal Investigator
- Principal Investigator
  
  YAMADA Toshiyuki
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  JUNTENDO UNIVERSITY
HDLアポリポ蛋白解析による全身性アミロイドーシスの生化学的診断法の検討Principal Investigator
- Principal Investigator
  
  山田俊幸
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Jichi Medical University
続発性アミロイドーシスにおける血清アミロイドA蛋白C末端の動態に関する研究Principal Investigator
- Principal Investigator
  
  山田俊幸
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Jichi Medical University
Change for Aging on Clinical Chemical Data
- Principal Investigator
  
  SUGITA Osamu
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Niigata University
Attempt to make Tumor Specific Human Monoclonal Antibody
- Principal Investigator
  
  YAKATA Minoru
- Project Period (FY)
  1987 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Laboratory medicine
- Research Institution
  Niigata University

[Book] AAアミロイドーシス診療ファイル2022
- Author(s)
  山田俊幸、右田清志、奥田泰章、黒田毅、中村正
- Total Pages
  138
- Publisher
  金芳堂
- ISBN
  9784765319164
- Data Source
  KAKENHI-PROJECT-17K09973
[Book] 検査値ガイド2011
- Author(s)
  山田俊幸
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-21590637
[Book] 検査と適応疾患2010
- Author(s)
  山田俊幸
- Publisher
  社会保険研究所
- Data Source
  KAKENHI-PROJECT-21590637
[Book] パーフェクトガイド検査値事典2010
- Author(s)
  山田俊幸
- Total Pages
  5
- Publisher
  総合医学社
- Data Source
  KAKENHI-PROJECT-21590637
[Book] 新版臨床免疫学第2版2009
- Author(s)
  山田俊幸
- Total Pages
  305
- Publisher
  講談社サイエンティフィック
- Data Source
  KAKENHI-PROJECT-21590637
[Book] 臨床検査ガイド、血清アミロイドA2007
- Author(s)
  山田俊幸
- Total Pages
  2
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-18590536
[Book] SAA(血清アミロイドA). 基準値と異常値の間2006
- Author(s)
  山田俊幸(河合忠編)
- Publisher
  中外医学社. 東京
- Data Source
  KAKENHI-PROJECT-18590536
[Book] 今日の治療指針、11.代謝疾患アミロイドーシス2003
- Author(s)
  山田俊幸
- Total Pages
  1
- Publisher
  医学書院
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590496
[Book] 今日の臨床検査
- Author(s)
  山田俊幸
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] Prevalence of systemic and local risk factors for pulmonary non-tuberculous mycobacterial disease in Japan: a single-institution study2023
- Author(s)
  Ryohei K, Sawahata M, Nakayama M, Yamada T, Taniguchi N, Bando M, Hagiwara K
- Journal Title
  
  J Rural Med
  
  Volume: 18 Issue: 3 Pages: 168-174
- DOI
  10.2185/jrm.2023-001
- ISSN
  1880-487X, 1880-4888
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07921
[Journal Article] The effects for inflammatory responses by CPP with different colloidal properties in hemodialysis patients.2022
- Author(s)
  Mukai H, Miura Y, Kotani K, Kotoda A, Kurosu H, Yamada T, Kuro-O M, Iwazu Y
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 21856-21856
- DOI
  10.1038/s41598-022-26166-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07921, KAKENHI-PROJECT-21K06423, KAKENHI-PROJECT-22K08316
[Journal Article] Calcium phosphate microcrystals in the renal tubular fluid accelerate chronic kidney disease progression2021
- Author(s)
  Shiizaki Kazuhiro、Tsubouchi Asako、Miura Yutaka、....Itoh Hiroshi、....Kuro-o Makoto
- Journal Title
  
  Journal of Clinical Investigation
  
  Volume: 131 Issue: 16
- DOI
  10.1172/jci145693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00535, KAKENHI-PROJECT-19K07921, KAKENHI-PROJECT-20K08613, KAKENHI-PROJECT-21K18270, KAKENHI-PROJECT-20K21506
[Journal Article] Glycosylated Bence Jones protein with poor thermal reactivity in heat coagulation tests2020
- Author(s)
  Imoto M, Watanabe K, Yoshida K, Maeda Y, Nakae K, Kamisako T, Yamada T.
- Journal Title
  
  Clin Lab 66:2365-2369,2020
  
  Volume: 66 Issue: 11/2020 Pages: 2365-2369
- DOI
  10.7754/clin.lab.2020.200304
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07921, KAKENHI-PROJECT-18K05446
[Journal Article] Effects of lipid composition on the structural properties of human serum amyloid A in reconstituted high-density lipoprotein particles2019
- Author(s)
  Hiroka Takase, Masafumi Tanaka, Yuki Nakamura, Shin-ya Morita, Toshiyuki Yamada, Takahiro Mukai
- Journal Title
  
  Chem. Phys. Lipids
  
  Volume: 221 Pages: 8-14
- DOI
  10.1016/j.chemphyslip.2019.03.001
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05660, KAKENHI-PROJECT-19K07921
[Journal Article] Calciprotein particles and fibroblast growth factor 23 contribute to the pathophysiology of hypercalcemia in a patient with renal sarcoidosis2019
- Author(s)
  Iwazu Yoshitaka、Kuro-o Makoto、Miura Yutaka、Takeda Shin-ichi、Yamada Toshiyuki、Nagata Daisuke
- Journal Title
  
  Clinical Kidney Journal
  
  Volume: ー Issue: 1 Pages: 421-423
- DOI
  10.1093/ckj/sfz086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08941
[Journal Article] The Ratio of Oxidized Lipoprotein(a) to Native Lipoprotein(a) and the Endothelial Function in Patients with Type 2 Diabetes Mellitus2019
- Author(s)
  Kotani Kazuhiko、Yamada Shingo、Takahashi Hirokazu、Iwazu Yoshitaka、Yamada Toshiyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 19 Pages: 4909-4909
- DOI
  10.3390/ijms20194909
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08941
[Journal Article] Detection of AA76, a common form of amyloid A protein, as a way of diagnosing AA amyloidosis2016
- Author(s)
  Junji Sato, Yasuaki Okuda, Takeshi Kuroda, Toshiyuki Yamada
- Journal Title
  
  Ann Clin Lab Sci
  
  Volume: 46 Pages: 147-153
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461471
[Journal Article] Detection of AA76, a Common Form of Amyloid A Protein, as a Way of Diagnosing AA Amyloidosis2016
- Author(s)
  Junji Sato, Yasuaki Okuda, Takeshi Kuroda, Toshiyuki Yamada.
- Journal Title
  
  Annals of Clinical & Laboratory Science
  
  Volume: 46 Pages: 147-153
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461471
[Journal Article] AA amyloid quantification in biopsy samples from stomach2012
- Author(s)
  Yamada T, Okuda Y
- Journal Title
  
  Ann Clin Lab Sci
  
  Volume: 42 Pages: 3-6
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] AAアミロイドーシスの病態とSAA2012
- Author(s)
  山田俊幸
- Journal Title
  
  臨床化学
  
  Volume: 41 Pages: 16-21
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 非特異炎症マーカー主要マーカーとしてのβ2-ミクログロブリン2011
- Author(s)
  山田俊幸
- Journal Title
  
  臨床検査
  
  Volume: 55 Pages: 395-400
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 特異炎症マーカー、主要マーカーとしてのβ2-ミクログロブリン2011
- Author(s)
  山田俊幸
- Journal Title
  
  臨床検査
  
  Volume: 55 Pages: 395-400
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 緊急報告すべき検査結果のすべて2011
- Author(s)
  山田俊幸
- Journal Title
  
  CRP.検査と技術
  
  Volume: 39 Pages: 795-797
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] Ageing : a risk factor for amyloid A amyloidosis in rheumatoid arthritis. Amyloid2011
- Author(s)
  Okuda Y, Yamada T, Matsuura M, Takasugi K, Goto M, Ageing
- Journal Title
  
  J Prot Fold Dis
  
  Volume: 18 Pages: 108-111
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 緊急報告すべき検査結果のすべて、CRP2011
- Author(s)
  山田俊幸
- Journal Title
  
  検査と技術
  
  Volume: 39 Pages: 795-797
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 広義のアポリポ蛋白,免疫グロブリン(IgG, IgA, IgM)2010
- Author(s)
  山田俊幸
- Journal Title
  
  SAA.臨床検査,検査と技術
  
  Volume: 54, 38
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] M蛋白検出法とその問題点2010
- Author(s)
  山田俊幸
- Journal Title
  
  臨床病理
  
  Volume: 58 Pages: 397-400
- NAID
  10026444860
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 広義のアポリポ蛋白.SAA2010
- Author(s)
  山田俊幸
- Journal Title
  
  臨床検査
  
  Volume: 54 Pages: 395-400
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 全身性アミロイドーシス2010
- Author(s)
  山田俊幸
- Journal Title
  
  検査と技術
  
  Volume: 38 Pages: 343-347
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] Bezafibrate and serum amyloid A-low-density lipoprotein complex in patients with type 2 diabetes mellitus and hypertriglyceridemia2010
- Author(s)
  Kotani K, Satoh N, Yamada T
- Journal Title
  
  Eur J Intern Med
  
  Volume: 21
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] Immunotargeting of apolipoprotein E in the amyloid. An initial trial in mice.2009
- Author(s)
  Yamada T, Someya T, Fujita S
- Journal Title
  
  Ann Clin Lab Sci 39
  
  Pages: 134-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Immunotargeting of apolipoprotein E in the amyloid : An initial trial in mice2009
- Author(s)
  Yamada T, Someya T, Fujita S
- Journal Title
  
  Ann Clin Lab Sci 39
  
  Pages: 134-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] Immunotargeting of apolipoprotein E in the amyloid : An initial trial in mice.2009
- Author(s)
  Yamada T, et al.
- Journal Title
  
  Ann Clin Lab Sci 2009 in press (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Differential affinity of serum amyloid Al isotypes for high-density lipop rotein2009
- Author(s)
  Yamada T, Sato J, Okuda Y
- Journal Title
  
  Amyloid : J Prot Fold Dis 16
  
  Pages: 196-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] AAアミロイドーシスの分子病態2009
- Author(s)
  山田俊幸
- Journal Title
  
  医学のあゆみ 229
  
  Pages: 327-331
- Data Source
  KAKENHI-PROJECT-21590637
[Journal Article] 関節リウマチ検査・診療の新展開. 1)炎症マーカー2008
- Author(s)
  山田俊幸
- Journal Title
  
  Medical Technology 36
  
  Pages: 23-26
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Increased susceptibility of serum amyloid 1.1 to degradation by MMP-1; potential explanation for higher risk of type AA amyloidosis.2008
- Author(s)
  van der Hilst JC, Yamada T, Op den Camp HJ, van der Meer JW, Drenth JP, Simon A
- Journal Title
  
  Rheumatology 47
  
  Pages: 1651-1654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Increased susceptibility of serum amyloid 1.1 to degradation by MMP-1 : potential explanation for higher risk of type AA amyloidosis.2008
- Author(s)
  van der Hilst JC, Yamada T, et al
- Journal Title
  
  Rheumatology 2008 ; 47:1651-1654. 47
  
  Pages: 1651-1654
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] 血液透析患者の血中β2-マイクログロブリン濃度変化における炎症の影響、第2報2006
- Author(s)
  佐藤孝彦, 山田俊幸, ほか
- Journal Title
  
  医学と薬学 55
  
  Pages: 615-620
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Serum amyloid A (SAA)-induced remodeling of CSF-HDL.2006
- Author(s)
  Miida T, Yamada T, Seino U, Ito M, Takahashi A, Kosuge K, Soda S, Hanyu O, Obayashi K, Miyazaki O, Okada M
- Journal Title
  
  Biochim Biophys Acta 1761
  
  Pages: 424-433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Serum amyloid A(SAA)-induced remodeling of CSF-HDL.2006
- Author(s)
  Miida T, Yamada T, et al.
- Journal Title
  
  Biochim Biophys Acta 1761
  
  Pages: 424-433
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] メトトレキセートが腎機能悪化を7年間抑制したと考えられる関節リウマチ誘発腎アミロイドーシス2006
- Author(s)
  岩本雅弘, 山田俊幸, ほか
- Journal Title
  
  臨床リウマチ 18
  
  Pages: 332-336
- Data Source
  KAKENHI-PROJECT-18590536
[Journal Article] Genetic effects on serum concentrations of serum amyloid A protein (SAA)2004
- Author(s)
  Toshiyuki Yamada
- Journal Title
  
  Clinical Chemistry 50
  
  Pages: 978-979
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590496
[Journal Article] Genetic effects on serym concentrations of serum amyloid A protein (SAA).2004
- Author(s)
  Yamada T
- Journal Title
  
  Clinical Chemistry 50
  
  Pages: 978-979
- Data Source
  KAKENHI-PROJECT-15590496
[Journal Article] Differential affinity of serum amyloid A1 isotypes for high density lipoprotein.
- Author(s)
  Yamada T, Sato J, Okuda Y
- Journal Title
  
  Amyloid in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590536
[Presentation] SAAとヒストンとの相互作用の解析2023
- Author(s)
  川口公平、佐藤純司、山田俊幸
- Organizer
  第10回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 組織沈着AA蛋白のプロテオーム解析より見出だされたSAAとヒストンとの結合能評価2023
- Author(s)
  川口公平、佐藤純司、山田俊幸
- Organizer
  第63回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] AA アミロイドーシスにおける沈着 AA 蛋白の翻訳後修飾分析2.2022
- Author(s)
  川口公平、佐藤純司、山田俊幸
- Organizer
  第62回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 組織沈着AA蛋白のプロテオーム解析2022
- Author(s)
  川口公平、佐藤純司、奥田恭章、黒田毅、山田俊幸
- Organizer
  第9回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] AA アミロイドーシスにおける沈着 AA 蛋白の翻訳後修飾分析2021
- Author(s)
  川口公平、佐藤純司、山田俊幸
- Organizer
  第61回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 組織沈着AA蛋白におけるメチオニン酸化の分析2021
- Author(s)
  川口公平、佐藤純司、奥田恭章、黒田毅、山田俊幸
- Organizer
  第8回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 腎組織に組織学的および生化学的に特異なSAA蛋白のサブタイプを認めた関節リウマチ合併AAアミロイドーシスの１例2021
- Author(s)
  黒田毅、上家潤一、伊藤由美、今井直史、長谷川絵理子、佐藤弘恵、小林大介、中枝武司、和田庸子、中野正明、成田一衛、山田俊幸
- Organizer
  第８回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09973
[Presentation] Massive renal AA-amyloidosis: a histologically and biochemically distinctive subtype of SAA protein in reactive systemic amyloidosis2020
- Author(s)
  Takeshi Kuroda, Junichi Kamiie, Yumi Ito, Naofumi Imai, Eriko Hasegawa, Daisuke Kobayashi, Hiroe Sato, Takeshi Nakatsue, Yoko Wada, Masaaki Nakano, Ichiei Narita, Toshiyuki Yamada
- Organizer
  The XVIth International Symposium on Amyloidosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09973
[Presentation] Massive renal AA-amyloidosis: a histologically and biochemically distinctive subtype of SAA protein in reactive systemic amyloidosis2020
- Author(s)
  Takeshi Kuroda, Junichi Kamiie, Yumi Ito, Naofumi Imai, Eriko Hasegawa, Daisuke Kobayashi, Hiroe Sato, Takeshi Nakatsue, Yoko Wada, Masaaki Nakano, Ichiei Narita, Toshiyuki Yamada
- Organizer
  The XVIIth International Symposiumon Amyloidosis
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09973
[Presentation] Analysis of AA protein species in serial biopsy samples from AA amyloidosis patients by MALDI-TOF MS2020
- Author(s)
  Kawaguchi K, Okuda Y, Yamada T
- Organizer
  XVIIth International Symposium on Amyloidosis.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] MALDI-TOF MSによるAAアミロイドーシス患者組織生検サンプルの経時的な分析2020
- Author(s)
  川口公平、山田俊幸
- Organizer
  第60回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] MALDI-TOF MSを用いた血清SAAの分析によるSAA1遺伝子型の同定2019
- Author(s)
  川口公平、山田俊幸
- Organizer
  第59回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 生検材料からのアミロイド内AA蛋白の分析2019
- Author(s)
  川口公平、奥田恭章、黒田毅、山田俊幸
- Organizer
  第63回日本リウマチ学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 血漿Calciprotein particle値から慢性腎臓病の高リン血症を再考する2019
- Author(s)
  岩津好隆, 黒尾誠, 椎崎和弘, 三浦裕, 金田るり, 黒須洋, 小藤田篤, 小谷和彦, 山田俊幸, 長田太助
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] MALDI-TOF MSによる生検組織片から抽出されたAA蛋白の分子構造分析2019
- Author(s)
  川口公平、奥田恭章、黒田毅、山田俊幸
- Organizer
  第7回日本アミロイドーシス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07921
[Presentation] 慢性腎臓病における尿細管リンおよび尿酸排泄と尿細管障害の関係　結晶化と腎障害の関係．2019
- Author(s)
  岩津好隆, 黒尾誠, 小谷和彦, 長田太助, 山本さやか, 鯉渕晴美, 紺野啓, 谷口信行, 山田俊幸
- Organizer
  日本臨床検査医学会
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] 慢性腎臓病におけるリン吸着薬が血清無機リン値と血漿CPP値に与える影響を比較する2018
- Author(s)
  岩津好隆, 小谷和彦, 黒尾誠, 長田太助, 山本さやか, 鯉渕晴美, 紺野啓, 谷口信行, 山田俊幸
- Organizer
  第６５回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] 慢性腎臓病におけるリン毒性マーカーとしての血漿Calciprotein particle2018
- Author(s)
  岩津好隆, 三浦裕, 黒尾誠, 小谷和彦, 長田太助, 山田俊幸
- Organizer
  第58回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] 血中CPPの新規測定法の確立2018
- Author(s)
  三浦裕，黒須洋, 岩津好隆, 小谷和彦, 山田俊幸, 黒尾誠
- Organizer
  第58回日本臨床化学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] 血管石灰化マーカーから慢性腎臓病の高リン血症を再検討する2018
- Author(s)
  岩津好隆，黒尾　誠，小谷和彦，椎崎和弘，長田太助，山田俊幸，谷口信行
- Organizer
  第５８回栃木総合医学会
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] 慢性腎臓病における尿沈査と尿細管障害の関連性　予備的検討2016
- Author(s)
  岩津好隆、小谷和彦、長田太助、黒尾誠、谷口信行、山田俊幸
- Organizer
  第63回日本臨床検査医学会学術集会・総会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-16K08941
[Presentation] 尿検査による腎アミロイドーシスの診断法および腎臓内のアミロイドの動態について2015
- Author(s)
  黒田　毅、小林大介、若松彩子、高井千夏、佐藤弘恵、中枝武司、和田庸子、中野正明、成田一衛、山田俊幸
- Organizer
  第60回日本リウマチ学会総会・学術集会
- Place of Presentation
  横浜
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-25461471
[Presentation] 尿検査による腎アミロイドーシスの診断と尿中のアミロイドの動態について2014
- Author(s)
  西　慎一、黒田　毅、伊藤由美、今井直史、中枝武司、和田庸子、中野正明、山田俊幸
- Organizer
  アミロイドーシスに関する調査研究班研究報告会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461471
[Presentation] 免疫固定法システムHydrasysによる非濃縮尿におけるBence Jones蛋白の検出2011
- Author(s)
  老沼弘俊、小谷和彦、簗瀬直穂美、山田俊幸
- Organizer
  第58回日本臨床検査医学会総会
- Place of Presentation
  岡山
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-21590637
[Presentation] 免疫固定法システムHydrasysによる非濃縮尿におけるBence Jones蛋白の検出2011
- Author(s)
  老沼弘俊、山田俊幸
- Organizer
  第36回日本骨髄腫研究会総会
- Place of Presentation
  東京
- Year and Date
  2011-11-12
- Data Source
  KAKENHI-PROJECT-21590637
[Presentation] 実験AAアミロイドーシスにおけるSAAとアポEの動態2011
- Author(s)
  山田俊幸、小谷和彦、佐藤純司
- Organizer
  第51回日本臨床化学会年次学術集会
- Place of Presentation
  札幌
- Year and Date
  2011-08-26
- Data Source
  KAKENHI-PROJECT-21590637
[Presentation] AAアミロイドーシスモデルマウスにおけるSAA、apoEの動態2011
- Author(s)
  山田俊幸
- Organizer
  第55回日本リウマチ学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-21590637
[Presentation] SAA1とHDLの親和性2010
- Author(s)
  山田俊幸、奥田恭章
- Organizer
  第54回日本リウマチ学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2010-04-23
- Data Source
  KAKENHI-PROJECT-21590637
[Presentation] 表面プラズモン共鳴によるSAA(血清アミロイドA)とHDLの親和性の検討(その2)2009
- Author(s)
  佐藤純司, 山田俊幸
- Organizer
  第49回日本臨床化学会年次学術集会
- Place of Presentation
  長崎大学(長崎)
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-21590637
[Presentation] 表面プラズモン共鳴によるSAA(血清アミロイドA)とHDLの親和性の検討2008
- Author(s)
  佐藤純司, 山田俊幸
- Organizer
  第48回日本臨床化学会年会
- Place of Presentation
  浜松
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-18590536
[Presentation] 表面プラズモン共鳴によるSAA(血清アミロイドA)とHDLの親和性の検討2008
- Author(s)
  佐藤純司, 山田俊幸
- Organizer
  第48回日本臨床化学会年会
- Place of Presentation
  浜松市
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-18590536
[Presentation] モノクロナル抗体の反応性を利用したSAA(血清アミロイドA)の構造・機能解析2007
- Author(s)
  佐藤純司, 山田俊幸
- Organizer
  第47回日本臨床化学会年会
- Place of Presentation
  大阪
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-18590536
[Presentation] モノクタナル抗体の反応性を利用したSAA(血清アミロイドA)の構造・機能解析2007
- Author(s)
  佐藤純司, 山田俊幸
- Organizer
  第47日本臨床化学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2007-11-23
- Data Source
  KAKENHI-PROJECT-18590536
[Presentation] SAAとHDLの親和性解析の基礎検討2006
- Author(s)
  山田俊幸
- Organizer
  第45回日本臨床化学会年会
- Place of Presentation
  東京6
- Year and Date
  2006-09-09
- Data Source
  KAKENHI-PROJECT-18590536

1. Kuroda Takeshi (00372475)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. YAKATA Minoru (20018352)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. SUGITA Osamu (10092701)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. Tanaka Masafumi (40411904)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 谷口信行 (10245053)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 中枝武司 (20464000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 和田庸子 (30608534)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
8. FUJII Yasutomo (00337338)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SATOH Junji (90536301)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. OGOSE Akira (80323963)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MIIDA Takashi (80260545)

# of Collaborated Projects: 1 results

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12. ITOH Yoshihisa (20129026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OKADA Masahiko (30018915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. Iwazu Yoshitaka (40424014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
15. 羽生忠正 (20189591)

# of Collaborated Projects: 1 results

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16. 黒尾誠 (10716864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
17. 小谷和彦 (60335510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
18. 上家潤一 (10400269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 川口公平 (20814651)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
20. 高山法也 (40807880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 笹沼英紀 (90511709)

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22. 小形幸代 (10448847)

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23. 秋山いわき (80192912)

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24. 力山敏樹 (80343060)

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25. 利府数馬 (60865715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. UCHIYAMA Kazuaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 入江喬介

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 中山勝司

# of Collaborated Projects: 1 results

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29. 桑名友美

# of Collaborated Projects: 1 results

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30. MORITA Shin-ya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 長谷川一宏

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# of Collaborated Products: 1 results
32. 伊藤裕

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# of Collaborated Products: 1 results

Yamada Toshiyuki 山田 俊幸

山田 俊幸 ヤマダ トシユキ

YAMADA Toshiyuki 山田 俊幸

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急性期蛋白SAAの分子修飾と炎症ベクトルの研究Principal Investigator

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Detection of low affinity autoantibodies like anti-amyloid antibodies by surface plasmon resonance analysis Detection of low affinity autoantibodies like anti-amyloid antibodies by surface plasmon resonance analysisPrincipal Investigator

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Functional analysis for serum amyloid A polymorphismPrincipal Investigator

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Immune targeting of apolipoprotein E in amyloid deposits ; a fundamental study using murine modelPrincipal Investigator

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Synthesis, metabolism andfibrillogenesis of serum amyloid A bymonocytes or macrophagesPrincipal Investigator

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Yamada Toshiyuki 山田俊幸

山田俊幸ヤマダトシユキ

YAMADA Toshiyuki 山田俊幸

[Book] 臨床検査ガイド、血清アミロイドA2007