Ogose Akira 生越章

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OGOSE Akira 越生章

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Researcher Number	80323963
Other IDs
External Links
Affiliation (Current)	2025: 新潟大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2025: 新潟大学, 医歯学総合研究科, 客員研究員 2016 – 2023: 新潟大学, 医歯学総合病院, 特任教授 2015: 新潟大学, 医歯学総合病院, 教授 2007: Niigata University, Institute of Meclicine and Dentistry, Associate Professor 2006: 新潟大学, 医歯学系, 助教授 2002: NIIGATA UNIVERSITY University Medical Hospital. Lecturer, 医学部附属病院, 講師
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Orthopaedic surgery / Orthopaedic surgery Except Principal Investigator Surgical dentistry
Keywords	Principal Investigator 免疫治療 / 骨軟部肉腫 / 脂肪肉腫 / PPAR α / SAA / 免疫細胞療法 / NK細胞関連受容体 / CAR-T細胞療法 / 希少がん / 難治性軟部肉腫 … More / リンパ球 / 中間群 / 骨軟部腫瘍 / 再発 / デスモイド腫瘍 / 骨巨細胞腫 / 免疫細胞 / CD163 / CD8 / M2マクロファージ / Ｍ２マクロファージ / 細胞障害性リンパ球 / 免疫療法 / dedifferentiaion / myxoid liposarcoma / prognosis / macrophage / HLA / immunotherapy / sarcoma / 免疫環境 / 肉腫 / CDK4阻害剤 / 骨外性骨肉腫 / MDM2 / osteosarcoma / CDK4 / liposarcoma / Surface structure / Micropore / Bone marrow cells / Calcium phosphate / Bone formation / マイクロポアー / 骨再生 / 再生医療 / 表面構造 / マイクロポア / 骨髄細胞 / リン酸カルシウム / 骨形成 / Fibrate / Reactive Amyloidsis / PPARα / フィブラート / 2次性アミロイドーシス … More Except Principal Investigator FGF2 / Implant / Bone regeneration / Culture / Periosteal cell / インプラント / 骨増生 / 培養 / 骨膜細胞 Less

Development of CAR-T cell therapy using NK cell-associated receptors for refractory rare soft tissue sarcomasPrincipal Investigator
- Principal Investigator
  
  生越章
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Niigata University
良悪性中間群骨軟部腫瘍における免疫環境の解析と新規治療法の開発Principal Investigator
- Principal Investigator
  
  生越章
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Niigata University
Immunotherapy for bone and soft tissue tumorsPrincipal Investigator
- Principal Investigator
  
  Ogose Akira
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Niigata University
CDK4 target therapy for bone and soft tissue tumorsPrincipal Investigator
- Principal Investigator
  
  Ogose Akira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
Development of new bone graft technique with autogenousbone and calcium phosphatePrincipal Investigator
- Principal Investigator
  
  OGOSE Akira
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Niigata University
2G allile of MMP-1 gene polymorphism increases risk of oral cancer
- Principal Investigator
  
  NAGATA Masaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Niigata University
Regulation of Reactive Amyloidosis via Activation of Peroxisome Proliferator Activated Receptor αPrincipal Investigator
- Principal Investigator
  
  OGOSE Akira, 羽生忠正
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  NIIGATA UNIVERSITY

All 2024 2022 2021 2019 2018 2017 2016 2015 2007 2006

All Journal Article Presentation

[Journal Article] Underlying synovial sarcoma undiagnosed for more than 20 years in a patient with regional pain: a case report.2024
- Author(s)
  Hatano H, Yamagishi T, Yanabashi K, Ogose A
- Journal Title
  
  Skeletal Radiol
  
  Volume: on line Issue: 1 Pages: 153-158
- DOI
  10.1007/s00256-024-04701-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09197
[Journal Article] NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma2022
- Author(s)
  Murayama Y, Kasahara Y, Kubo N, Shin C, Imamura M, Oike N, Ariizumi T, Saitoh A, Baba M, Miyazaki T, Suzuki Y, Ling Y, Okuda S, Mihara K, Ogose A, Kawashima H, Imai C.
- Journal Title
  
  Transl Oncol
  
  Volume: 25 Pages: 101521-101521
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K09197
[Journal Article] Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas2021
- Author(s)
  Oike N, Kawashima H, Ogose A et al
- Journal Title
  
  Cancer Immunology Immunotherapy
  
  Volume: ahead on print Issue: 12 Pages: 3489-3499
- DOI
  10.1007/s00262-021-02928-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09098, KAKENHI-PROJECT-19K08317
[Journal Article] Prognostic impact of the tumor immune microenvironment in synovial sarcoma2018
- Author(s)
  Oike Naoki、Kawashima Hiroyuki、Ogose Akira、Hotta Tetsuo、Hatano Hiroshi、Ariizumi Takashi、Sasaki Taro、Yamagishi Tetsuro、Umezu Hajime、Endo Naoto
- Journal Title
  
  Cancer Science
  
  Volume: 109 Issue: 10 Pages: 3043-3054
- DOI
  10.1111/cas.13769
- Data Source
  KAKENHI-PROJECT-18K09098
[Journal Article] Frequent expression of human leukocyte antigen class I and the status of intratumoral immune cells in alveolar soft part sarcoma2017
- Author(s)
  Ogose A　et al
- Journal Title
  
  Oncol Lett
  
  Volume: 13 Issue: 4 Pages: 2169-2176
- DOI
  10.3892/ol.2017.5696
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10434
[Journal Article] 骨・軟部腫瘍診療におけるピットフォールー腫瘍が怖くなくなるためにー2016
- Author(s)
  生越章
- Journal Title
  
  日本整形外科学会雑誌
  
  Volume: 90 Pages: 229-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10434
[Journal Article] Disappearance of giant cells and presence of newly formed bone in the pulmonary metastasis of sacral giant cell tumor following Denosumab treatment2016
- Author(s)
  Yamagishi T, Kawashima H, Ogose A, Sasaki T, Hotta T, Inagawa S, Umezu H, Endo N
- Journal Title
  
  Oncology Letters１１
  
  Volume: １１ Pages: 243-246
- Data Source
  KAKENHI-PROJECT-15K10434
[Journal Article] 骨転移とともに生きる2016
- Author(s)
  生越章
- Journal Title
  
  新潟県医師会報
  
  Volume: 797 Pages: 2-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10434
[Journal Article] Receptor-activator of nuclear kappa B ligand expression as a new therapeutic target in primary bone tumors2016
- Author(s)
  Yamagishi T, Kawashima H, Ogose A他
- Journal Title
  
  PLos One
  
  Volume: 10
- Data Source
  KAKENHI-PROJECT-15K10434
[Journal Article] Effect of temozolomide on the vaiability of musculoskeletal sarcoma cells2015
- Author(s)
  Kusaba Y, Kawashima H, Ogose A, Sasaki T, Ariizumi T, Hotta T, Endo N.
- Journal Title
  
  Oncol Lett
  
  Volume: 10 Pages: 2511-2518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10434
[Journal Article] 生検にて診断した骨斑紋症(オステオポイキローシス)の1例2007
- Author(s)
  庄司寛和生越章, 他
- Journal Title
  
  新潟整外研会誌 23
  
  Pages: 5-8
- NAID
  110006316857
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] アルコール性肝障害を有する患者の骨盤骨折2007
- Author(s)
  今尾寛太徳永邦彦生越章, 他
- Journal Title
  
  新潟整外研会誌 23
  
  Pages: 9-12
- NAID
  110006316859
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] Diagnosis of osteopoikilosis by open biopsy2007
- Author(s)
  Syouji, H, Ogose, A, et. al.
- Journal Title
  
  Arch Niigata Soc Orthop Surg 23
  
  Pages: 5-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] Pelvic fracture in patients with liver injury2007
- Author(s)
  Imao, K, Tokunaga, K, Ogose, A, et. al.
- Journal Title
  
  Arch Niigata Soc Orthop Surg Alcholoc 23
  
  Pages: 9-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] Establishement of novel human dedifferentiated chondrosarcoma cell line with osteoblastic differentiation2007
- Author(s)
  Kudo N, Ogose A, et. al.
- Journal Title
  
  Virchow Archiv 451
  
  Pages: 691-699
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] アルコール性肝障害を有する患者の骨盤骨折2007
- Author(s)
  今尾貫太, 徳永邦彦, 生越章, 他
- Journal Title
  
  新潟整外研会誌 23
  
  Pages: 9-12
- NAID
  110006316859
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] 生検にて診断した骨斑紋症(オステオポイキローシス)の1例2007
- Author(s)
  庄司寛和, 生越章, 他
- Journal Title
  
  新潟整外研会誌 23
  
  Pages: 5-8
- NAID
  110006316857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] Establishement of novel human dedifferentiated chondrosarcoma cell line with osteoblastic differentiation2007
- Author(s)
  Kudo, N, Ogose, A, et. al.
- Journal Title
  
  Virchows Archiv 451
  
  Pages: 691-699
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] Osteoinduction with highly purified beta-tricalcium phosphate in dog dorsal muscles and the proliferation of osteoclasts before heterotopic bone formation2006
- Author(s)
  Kondo N, Ogose A, et. al.
- Journal Title
  
  Biomaterials 26
  
  Pages: 4419-4427
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] Osteoinduction with highly purified beta-tricalcium phosphate in dog dorsal muscles and the proliferation of osteoclasts before heterotopic bone formation2006
- Author(s)
  Kondo N, Ogose A et al.
- Journal Title
  
  Biomaterials 27
  
  Pages: 4419-4427
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] β-リン酸三カルシウムのマイクロポア内におけるI型コラーゲンの形成2006
- Author(s)
  生越章, 他
- Journal Title
  
  Orthopaedic Ceramic Implants 26
  
  Pages: 25-30
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] FormatioFormation of thpe I collagen within the micropore of Highly purified beta-tricalcium phsphate2006
- Author(s)
  Ogose, A, et. al.
- Journal Title
  
  Orthopaedic Ceramic Implants 26
  
  Pages: 25-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] High dose glucocorticoid hampers bone formation and resorption after bone marrow ablation in rat2006
- Author(s)
  Kondo N, Ogose A, et. al.
- Journal Title
  
  Microscopy Research and Technique 69
  
  Pages: 839-846
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] High dose glucocorticoid hampers bone formation and resorption after bone marrow ablation in rat2006
- Author(s)
  Kondo, N, Ogose, A, et. al.
- Journal Title
  
  Microscopy Research and Technique 69
  
  Pages: 839-846
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] 人工骨補填材料に見られる骨形成2006
- Author(s)
  生越章
- Journal Title
  
  日骨形態誌 16
  
  Pages: 31-38
- NAID
  10020622528
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] etal Osteoinduction with highly purified beta-tricalcium phosphate in dog dorsal muscles and the proliferation of osteoclasts before heterotopic bone formation2006
- Author(s)
  Kondo, N, Ogose, A
- Journal Title
  
  Biomaterials 26
  
  Pages: 4419-4427
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] 「研究成果報告書概要(欧文)」より2006
- Author(s)
  Ogose, A
- Journal Title
  
  Bone formation in calcium phosphate 16
  
  Pages: 31-38
- Data Source
  KAKENHI-PROJECT-18591658
[Journal Article] 人工骨補填材料にみられる骨形成2006
- Author(s)
  生越章
- Journal Title
  
  日骨形態誌 16
  
  Pages: 31-38
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] Clinical Significance of Tumor Immune Microenvironment in Soft tissue sarcoma2019
- Author(s)
  Oike N, Kawashima H, Ogose A et al
- Organizer
  AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09098
[Presentation] 囲2重結紮法を用いた易出血性良性腫瘍に対する手術療法2016
- Author(s)
  生越章他
- Organizer
  日本整形外科学会総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K10434
[Presentation] Clinical use of beta-tricalcium phosphate in orthopedic Surgery2016
- Author(s)
  Ogose A
- Organizer
  The 2nd International Orthopedics Academic week of Zonngshan Hospital, Fudan University,
- Place of Presentation
  上海（中華人民共和国）
- Year and Date
  2016-04-19
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10434
[Presentation] 脂肪腫と高分化型脂肪肉腫の腫瘍倍加時間の比較検討2015
- Author(s)
  生越章、川島寛之、佐々木太郎、山岸哲郎、堀田哲夫、遠藤直人
- Organizer
  第３０回日本整形外科学会基礎学術集会
- Place of Presentation
  富山国際会議場（富山県、富山市）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-15K10434
[Presentation] 高純度β-リン酸三カルシウム(β-TCP)にみられる骨形成の組織学的解析2007
- Author(s)
  生越章, 他
- Organizer
  第80回日本整形外科学会総会
- Place of Presentation
  神戸
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] Influence of micropore structure For bone formation in tricalcium phosphate in dog2007
- Author(s)
  Ariizumi, T, Ogose, A, et. al.
- Organizer
  22th Annual Research Meeting of the Japanese Orthopaedic Association
- Place of Presentation
  Hamamatsu
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] イヌ背筋内移植βリン酸三カルシウム(β-TCP)の骨誘導におけるマイクロポアの意義2007
- Author(s)
  有泉高志生越章, 他
- Organizer
  第22回日本整形外科学会基礎瘍学術集会
- Place of Presentation
  浜松
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] イヌ背筋内移植βリン酸三カルシウム(β-TCP)の骨誘導におけるマイクロポアの意義2007
- Author(s)
  有泉高志、生越章, 他
- Organizer
  第22回日本整形外科学会基礎学術集会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] 株化ヒト骨芽細胞様細胞とリン酸カルシウムを用いた新規人工骨の開発2007
- Author(s)
  生越章, 他
- Organizer
  第2回新潟細胞再生療法シンポジウム
- Place of Presentation
  新潟
- Year and Date
  2007-04-19
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] Development of new artificial bone with bone regeneration2007
- Author(s)
  Ogose, A
- Organizer
  630th Niigata Medical Association
- Place of Presentation
  Niigata
- Year and Date
  2007-04-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] 骨再性能をもつ新規人工骨の開発2007
- Author(s)
  生越章
- Organizer
  第630回新潟医学会
- Place of Presentation
  新潟
- Year and Date
  2007-04-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] New bone graft technique with cultured osteoblast like Cells with calcium phosphate2007
- Author(s)
  Ogose, A, et. al.
- Organizer
  2nd Niigata Cell regeneration synposium
- Place of Presentation
  Niigata
- Year and Date
  2007-04-19
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] Histological assesment of bone formation In tricalcium phosphate2007
- Author(s)
  Ogose, A, et. al.
- Organizer
  80th Japanese Orthopaedic Assocaition
- Place of Presentation
  Kobe
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] Bone formation of beta-tricicium phosphate In dog dorsal muscle2006
- Author(s)
  Kondo, N, Ogose, A, et. al.
- Organizer
  39th Annual Musculoskeletal Tumor Meeting of the Japanese Orthopaedic Association
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] Bone formation of beta-tricalcium phosphate With human bone marrow in SCID mouse2006
- Author(s)
  Kudo, N, Ogose, A, et. al.
- Organizer
  39th Annual Musculoskeletal Tumor Meeting of the Japanese Orthopaedic Association
- Place of Presentation
  Sapporo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] ヒト骨髄液含有β-TCPのSCIDマウスへの移植2006
- Author(s)
  工藤尚子生越章, 他
- Organizer
  第39回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591658
[Presentation] β-リン酸三カルシウムの犬背筋内への単独移植における骨誘導能の解析2006
- Author(s)
  近藤直樹生越章, 他
- Organizer
  第39回日本整形外科学会骨・軟部腫瘍学術集会
- Place of Presentation
  札幌
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591658

1. YAMADA Toshiyuki (50211636)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. NAGATA Masaki (10242439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. NAKATA Koh (80207802)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TABATA Yasuhiko (50211371)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 羽生忠正 (20189591)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 星名秀行 (30173587)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 川島寛之 (30361900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 今井千速 (90419284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ogose Akira 生越 章

OGOSE Akira 越生 章

Research Projects

Research Products

Co-Researchers

Development of CAR-T cell therapy using NK cell-associated receptors for refractory rare soft tissue sarcomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

良悪性中間群骨軟部腫瘍における免疫環境の解析と新規治療法の開発Principal Investigator

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Immunotherapy for bone and soft tissue tumorsPrincipal Investigator

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CDK4 target therapy for bone and soft tissue tumorsPrincipal Investigator

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Development of new bone graft technique with autogenousbone and calcium phosphatePrincipal Investigator

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2G allile of MMP-1 gene polymorphism increases risk of oral cancer

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Regulation of Reactive Amyloidosis via Activation of Peroxisome Proliferator Activated Receptor αPrincipal Investigator

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[Journal Article] Underlying synovial sarcoma undiagnosed for more than 20 years in a patient with regional pain: a case report.2024

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[Journal Article] NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma2022

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[Journal Article] Human leukocyte antigen I is significantly downregulated in patients with myxoid liposarcomas2021

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[Journal Article] Prognostic impact of the tumor immune microenvironment in synovial sarcoma2018

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[Journal Article] Frequent expression of human leukocyte antigen class I and the status of intratumoral immune cells in alveolar soft part sarcoma2017

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[Journal Article] 骨・軟部腫瘍診療におけるピットフォールー腫瘍が怖くなくなるためにー2016

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[Journal Article] Disappearance of giant cells and presence of newly formed bone in the pulmonary metastasis of sacral giant cell tumor following Denosumab treatment2016

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[Journal Article] 骨転移とともに生きる2016

Ogose Akira 生越章

OGOSE Akira 越生章