KAWANO KENJI 河野憲司

… Alternative Names

河野憲司カワノケンジ

kawano Kenji 河野憲司

KAWANO Kenji 河野憲司

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Researcher Number	50214664
Other IDs
External Links
Affiliation (Current)	2025: 大分大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 大分大学, 医学部, 教授 2014 – 2017: 大分大学, 医学部, 教授 2008 – 2010: Oita University, 医学部, 教授 2003 – 2005: 大分大学, 医学部, 助教授 2001 – 2002: Faculty of Medicine, OITA MEDICAL UNIVERSITY, Associate Professor, 医学部, 助教授 … More 1999 – 2000: 大分医科大学, 医学部, 講師 1997: Oita Medical University, Faculty of Medicine, Department of Oral and Maxillo-Facial Surgery, Lecturer, 医学部, 講師 1992 – 1997: 大分医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathobiological dentistry/Dental radiology / Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Surgical dentistry / Surgical dentistry / 外科・放射線系歯学
Keywords	Principal Investigator 口腔扁平上皮癌 / 細胞外マトリックス / インテグリン / 転移 / hypoxia-inducible factor / multicellular aggregate / 上皮間葉転換 / 低酸素環境 / 3次元癌微小環境モデル / GSK-3β … More / Extracellular matrix / カドヘリン / integrin / 浸潤 / 口腔癌 / メタボローム解析 / 癌悪性形質 / 癌微小環境 / ErbBファミリー / 悪性形質 / 3次元微小環境モデル / Erbファミリー / HIF1α / Ras-MAPK pathway / PI3K-Akt pathway / Cyclin D1 / Oral sqaumous cell carcinoma / セリン残基リン酸化 / PI3K / Erk / Akt / Ras-MAPK経路 / PI3K-Akt経路 / サイクリンD1 / Laminin5 / α3β1 integrin / β catenin / E-cadherin / Cell scattering / Cell-cell adhesion / Oral squaumous cell carcinoma / 細胞外基質タンパク / カテニン / Eカドヘリン / ラミニン5 / α3β1インテグリン / βカテニン / E-カドヘリン / 細胞分散 / 細胞間接着 / prognostic factor / biological malignancy grade / gene amplification / oncogene / oral squamous cell carcinoma / 生物学的悪性度 / 予後 / 生物学的悪性癌 / 遺伝子増幅 / 癌遺伝子 / 細胞接着 / Her3/ErbB3 / HIF 1α / laminin 5 / ILK / 浸潤・転移抑制療法 / 口腔扁平上癌 / anoikis / アノイキス / 接着分子 / ヌードマウス / ヒト由来癌細胞株 … More Except Principal Investigator 口腔癌 / histochemistry / blood vessels / oral cancer / リンパ節転移 / リンパ管 / 早期発見 / 癌抑制遺伝子 / 口腔扁平上皮癌 / うがい液 / 前癌病変 / エピゲノム / DNAメチル化 / がん検診 / lymphangiogenesis / lymphatics / 新生リンパ管 / lymphnode metastasis / tongue carcinoma / lymphtics / 免疫組織化学 / 酵素組織化学 / 実験舌癌 / Flt-4 / 5'-nucleotidase / experimental study / tongue cancer / lymphatic vessels / lymphatic network / 組織化学 / 舌癌 / 血管 / sensitivity to anti-cancer drugs / invasion properties / proliferative activities / selection of treatment modalities / clinical malignancy grade / oral cancers / oral tumors / 抗癌剤感受性 / 浸潤能 / 増殖能 / 治療法選択 / 臨床的悪性度 / 口腔領域腫瘍 Less

Investigation on the mechanism of hypoxia-induced epithelial-mesenchymal transition using 3-dimentional tumor microenvirnment modelPrincipal Investigator
- Principal Investigator
  
  河野憲司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Oita University
Mechanism of hypoxia-induced progression of malignant phenotype in oral cancers: Analysis by the 3-dimentional microenvironment model.Principal Investigator
- Principal Investigator
  
  河野憲司
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Oita University
Noninvasive detection of oral cancer and precancerous lesion using aberrant DNA methylation in gargle fluid samples
- Principal Investigator
  
  Hamada Tomofumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kagoshima University
Establishment of anti-invasion/metastasis therapy targeting integrin-related molecules in oral squamous cell carcinomasPrincipal Investigator
- Principal Investigator
  
  kawano Kenji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Oita University
Establishment of invasion/metastasis inhibition therapy against oral squamous cell carcinomas : a basic study.Principal Investigator
- Principal Investigator
  
  KAWANO Kenji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Oita University
Modulation of Cyclin D1 Expression by Integrin Signals in Oral Squamous Carcinoma CellsPrincipal Investigator
- Principal Investigator
  
  KAWANO Kenji
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Oita University
  大分医科大学
Experimental Study of Lymphangiogenesis and Lymphatic Networks in Oral Cancer
- Principal Investigator
  
  MATSUMOTO Yushi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Oita University
  大分医科大学
Fine Structure and Distribution of Lymphatic Network In Oral Cancer, Histochemical
- Principal Investigator
  
  MATSUMOTO Yushi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Oita Medical University
Modulation of Cell-Cell Adhesion by Integrin Signals in Oral Squamous Carcinoma CellsPrincipal Investigator
- Principal Investigator
  
  KAWANO Kenji
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  大分医科大学
ヌードマウス自然転移実験系によるヒト口腔扁平上皮癌の転移に関する研究Principal Investigator
- Principal Investigator
  
  河野憲司
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Surgical dentistry
- Research Institution
  大分医科大学
Detection of oncogene amplification and its clinical significance in oral squamous cell carcinomasPrincipal Investigator
- Principal Investigator
  
  KAWANO Kenji, 清水正嗣
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Oita Medical University
In Vitro Studies on the Evaluation of Clinical Malignancy Grade and the Selection of Treatment Modalities for Oral Tumors
- Principal Investigator
  
  SHIMOZU Masatsugu
- Project Period (FY)
  1992 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  外科・放射線系歯学
- Research Institution
  Oita Medical University

All 2017 2016 2006 2005

All Journal Article

[Journal Article] Relationship between proliferative activity of tumor cells and the enlargement pattern of metastatic lymph nodes in oral squamous cell carcinomas2017
- Author(s)
  Tatsuyuki Kono, Yoshihiro Takahashi, Lazuhiro Kawamura, NOriaki Yamamoto, Ayaka Abe, Kenji Kawano
- Journal Title
  
  Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
  
  Volume: 29 Issue: 2 Pages: 116-121
- DOI
  10.1016/j.ajoms.2016.09.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462846
[Journal Article] 肺転移を生じた第1病期の舌類基底扁平上皮癌の1例2016
- Author(s)
  阿部史佳、山本哲彰、河野辰行、高橋喜浩、河野憲司
- Journal Title
  
  頭頸部癌
  
  Volume: 42 Pages: 393-399
- NAID
  130005395152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26462846
[Journal Article] Predictive value of laminin-5 and MT1-MMP expression for cervical lymphnode metastasis in T1 and T2 squamous cell carcinomas of the tongue and floor of the mouth2006
- Author(s)
  Kenji Kawano, Shigetaka Yanagisawa
- Journal Title
  
  Head and Neck 28(In press)
- Data Source
  KAKENHI-PROJECT-15592000
[Journal Article] Intratumoral expression of thymidylate synthase is an independent Predictor of prognosis in patients with squamous cell carcinoma of the tongue : results from a retrospective study2006
- Author(s)
  Kenji Kawano et al.
- Journal Title
  
  International Journal of Oral & Maxillofacial Surgery 35
  
  Pages: 258-264
- Data Source
  KAKENHI-PROJECT-15592000
[Journal Article] Roles of N-cadherin in invasion and metastasis of E-cadherin-negative oral squamous carcinoma cell lines2005
- Author(s)
  Kenji Kawano et al.
- Journal Title
  
  Oral Oncology ; Proceedings of 10th ICOOC 10
  
  Pages: 171-174
- Data Source
  KAKENHI-PROJECT-15592000

1. TAKAHASHI Yoshihiro (60347028)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
2. SHIMOZU Masatsugu (90013846)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. MATSUMOTO Yushi (10239121)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. YANAGISAWA Shigetaka (90053222)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 阿部史佳 (00718421)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 河野辰行 (20548143)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. KIMURA Mitsutaka (70047801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUSHIMA Rintaro (10209546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MIZUKI Harumi (40145397)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. ONO Keiichiro (10191967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRANO Kimihiko (20325723)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Hamada Tomofumi (00444894)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Yamada Norisige (60625242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 吉岡俊一 (20599659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 横山勢也 (20569941)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 杉浦剛 (40322292)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 川村和弘 (20815005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKAMURA Kodai

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

KAWANO KENJI 河野 憲司

河野 憲司 カワノ ケンジ

kawano Kenji 河野 憲司

KAWANO Kenji 河野 憲司

Research Projects

Research Products

Co-Researchers

Investigation on the mechanism of hypoxia-induced epithelial-mesenchymal transition using 3-dimentional tumor microenvirnment modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of hypoxia-induced progression of malignant phenotype in oral cancers: Analysis by the 3-dimentional microenvironment model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Noninvasive detection of oral cancer and precancerous lesion using aberrant DNA methylation in gargle fluid samples

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of anti-invasion/metastasis therapy targeting integrin-related molecules in oral squamous cell carcinomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of invasion/metastasis inhibition therapy against oral squamous cell carcinomas : a basic study.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulation of Cyclin D1 Expression by Integrin Signals in Oral Squamous Carcinoma CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Experimental Study of Lymphangiogenesis and Lymphatic Networks in Oral Cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fine Structure and Distribution of Lymphatic Network In Oral Cancer, Histochemical

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Modulation of Cell-Cell Adhesion by Integrin Signals in Oral Squamous Carcinoma CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヌードマウス自然転移実験系によるヒト口腔扁平上皮癌の転移に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Detection of oncogene amplification and its clinical significance in oral squamous cell carcinomasPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

In Vitro Studies on the Evaluation of Clinical Malignancy Grade and the Selection of Treatment Modalities for Oral Tumors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Relationship between proliferative activity of tumor cells and the enlargement pattern of metastatic lymph nodes in oral squamous cell carcinomas2017

KAWANO KENJI 河野憲司

河野憲司カワノケンジ

kawano Kenji 河野憲司

KAWANO Kenji 河野憲司