YOKOYAMA Seiya 横山勢也

Researcher Number	20569941
Other IDs
External Links
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 助教
Affiliation (based on the past Project Information) *help	2015 – 2025: 鹿児島大学, 医歯学域医学系, 助教 2014: 鹿児島大学, 大学院医歯学総合研究科, 助教 2012 – 2014: 鹿児島大学, 医歯(薬)学総合研究科, 助教 2013: 鹿児島大学, 医歯学総合研究科, 助教 2011: 鹿児島大学, 大学院・医歯学総合研究科, 助教 2011: 鹿児島大学, 大学院・医歯学総合研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Experimental pathology / Tumor diagnosis Except Principal Investigator Basic Section 49020:Human pathology-related / Human pathology / Basic Section 56010:Neurosurgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Basic Section 57060:Surgical dentistry-related / Surgical dentistry / Tumor diagnostics
Keywords	Principal Investigator 予後予測 / DNA methylation / DNAメチル化 / 機械学習 / 胆管癌 / エピジェネティクス / ムチン / 膵臓癌 / prognosis prediction / BSAS … More / NGS / cholangiocarcinoma / PDAC / mucin / 判別モデル / MPS / バイオマーカー / リキッドバイオプシ / 早期発見 / 次世代シークエンサー / DNA methyaltion / ＤＮＡメチル化 / 次世代シークエンス / 予測モデル / 悪性度予測 / 膵液 / 術後予測 / DNAのメチル化解析 / 臨床検体解析 / がん / MUC2 / 膵癌 / epigenetics / CA19-9 / prognosis / MUC4 / MUC1 / pancreas / DNA脱メチル化 / 肺癌 / ten eleven translocation / demethylation / lung adenocarcinomas … More Except Principal Investigator MUC1 / MUC4 / ムチン抗原 / 病理学 / 意義不明変異 / ムチン / 膵胆管系腫瘍 / MUC16 / 予後因子 / 膵胆道腫瘍 / 病理 / 膵胆道系腫瘍 / prognosis / methylation / MUC / 早期診断 / DNAメチル化 / 膠芽腫 / ゲノム編集 / 飽和ゲノム編集 / バイオマーカー / 機械学習 / 口腔扁平上皮癌 / うがい液 / エピゲノム / がん検診 / 口腔癌 / 予後 / 膵癌 / MUC17 / KRAS遺伝子 / 低栄養 / 低酸素 / オートファジ― / 遺伝子パネル検査 / VUS / 空間的プロテオミクス解析 / プロテオミクス解析 / ゲノムプロファイル / EGFR / MALAT1 / ノンコーディングRNA / がん遺伝子 / PDGFRA遺伝子 / 口腔がん / コピー数 / プレシジョン治療 / 口腔前癌病変 / microRNA / 口腔癌検診 / miRNA / マイクロRNA / シェーグレン症候群 / リキッドバイオプシー / エピジェネティクス / 治療効果判定 / 転写制御 / 乳癌 / アロマターゼ / 早期発見 / 癌抑制遺伝子 / 前癌病変 / メチル化 / 膵液 / 膵臓 / がんの個性診断 / DANメチル化 / 膵胆管系癌 / 低酸素応答性 / 悪性度 / gastric-type IPMN / intestinal-type IPMN / 異常糖鎖修飾 / angiogenesis / diagnosis / DNA methylation / mucin / IPMN / MUC2 Less

Developments in pancreatic cancer therapy targeting autophagy induced by MUC1 in hypoxia and malnutrition.
- Principal Investigator
  
  古川龍彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kagoshima University
飽和ゲノム編集の網羅性を用いて遺伝子変異の特性を多方面から検証する
- Principal Investigator
  
  濱田大治
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
ノンコーディングRNAを転写するMALAT1遺伝子のコーディングしない新規機能の解析
- Principal Investigator
  
  野口紘嗣
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kagoshima University
機械学習を用いた胆管癌悪性度予測モデルの構築Principal Investigator
- Principal Investigator
  
  横山勢也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
膠芽腫におけるEGFR意義不明変異の機能解析
- Principal Investigator
  
  霧島茉莉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kagoshima University
膠芽腫におけるドライバー遺伝子変異の空間的プロテオミクスへの基盤構築
- Principal Investigator
  
  比嘉那優大
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Kagoshima University
PDGFRA遺伝子変異の抗がん剤感受性マップの作製
- Principal Investigator
  
  濱田大治
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
Biomarker investigation of Pancreatobiliary neoplasm for early diagnosis and tratment
- Principal Investigator
  
  Higashi Michiyo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kagoshima University
Construction of DNA Methylation Markers for liqid biopsy of Pancreatic Cancer.Principal Investigator
- Principal Investigator
  
  Yokoyama Seiya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
Oral Cancer Precision Therapy Based on Integrated Multi-Omics Analysis of Gargle Samples
- Principal Investigator
  
  HAMADA Tomofumi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Social medical corporation Hakuaikai (Clinical Research Center)
  Kagoshima University
Basic research for the development of novel aromatase inhibitors against breast cancer
- Principal Investigator
  
  Hamada Taiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kagoshima University
Establishment of early diagnosis and treatment effect prediction method for pancreatobiliary neoplasm
- Principal Investigator
  
  Higashi Michiyo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kagoshima University
A fundamental study for construction of bile duct cancer early diagnosis method by DNA methylation analysis.Principal Investigator
- Principal Investigator
  
  Yokoyama Seiya
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kagoshima University
Attempt to establishment of early diagnosis and prediction of therapeutic response in pancreatobiliary neoplasms
- Principal Investigator
  
  HIGASHI Michiyo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kagoshima University
Noninvasive detection of oral cancer and precancerous lesion using aberrant DNA methylation in gargle fluid samples
- Principal Investigator
  
  Hamada Tomofumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Kagoshima University
A fundamental study for construction of PDAC early diagnosis method by DNA methylation analysis.Principal Investigator
- Principal Investigator
  
  Yokoyama Seiya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kagoshima University
膵液を用いた新規メチル化解析法による膵癌の早期診断予測法の構築
- Principal Investigator
  
  米澤傑
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Kagoshima University
Establishment of early diagnosis of pabcreatobiliary neoplasm
- Principal Investigator
  
  HIGASHI Michiyo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kagoshima University
Basic research for early diagnosis of lung carcinomas by the application of DNA methylation analysisPrincipal Investigator
- Principal Investigator
  
  YOKOYAMA Seiya
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Kagoshima University
Establishment of early diagnosis system of pancreatobiliary carcinomas by the application of mucin expression profiles
- Principal Investigator
  
  YONEZAWA Suguru
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  Kagoshima University
Investigation of prognostic factor in pancreatobiliary neoplasm
- Principal Investigator
  
  HIGASHI Michiyo
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kagoshima University

[Book] 胆と膵 IPMN大全　IPMNの歴史的変遷　IPMNにおけるMUC発現とその評価の歴史2020
- Author(s)
  東美智代、横山勢也、米澤傑、谷本昭英
- Total Pages
  58
- Publisher
  医学図書出版
- ISBN
  9784865173956
- Data Source
  KAKENHI-PROJECT-18K07019
[Book] 新規DNAメチル化解析法による新しい予後マーカーの開発2016
- Author(s)
  横山勢也、東美智代
- Publisher
  月刊「化学工業」
- Data Source
  KAKENHI-PROJECT-15K21247
[Book] 病理診断に役立つ分子生物学(病理と臨床臨時増刊号 Vol.29) (分担執筆), 第 2 部病理診断医になじみのある疾患関連分子, MUC 解説編. (金井弥栄, 石川俊平, 池田栄二;編集)2011
- Author(s)
  米澤傑, 山田宗茂, 横山勢也, 北本祥, 田畑和宏, 東美智代
- Total Pages
  545
- Publisher
  株式会社文光堂
- Data Source
  KAKENHI-PROJECT-23390085
[Book] 病理診断に役立つ分子生物学(病理と臨床臨時増刊号 Vol.29) (分担執筆), 第 2 部病理診断医になじみのある疾患関連分子, MUC 診断編. (金井弥栄, 石川俊平, 池田栄二;編集)2011
- Author(s)
  米澤傑, 山田宗茂, 横山勢也, 北本祥, 田畑和宏, 東美智代
- Total Pages
  545
- Publisher
  株式会社文光堂, 東京
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] Genome Editing Using Cas9 Ribonucleoprotein Is Effective for Introducing PDGFRA Variant in Cultured Human Glioblastoma Cell Lines2022
- Author(s)
  Hamada Taiji、Yokoyama Seiya、Akahane Toshiaki、Matsuo Kei、Tanimoto Akihide
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 1 Pages: 500-500
- DOI
  10.3390/ijms24010500
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07305
[Journal Article] Gallbladder microbiota composition is associated with pancreaticobiliary and gallbladder cancer prognosis.2022
- Author(s)
  Kirishima M, Yokoyama S, Matsuo K, Hamada T, Shimokawa M, Akahane T, Sugimoto T, Tsurumaru H, Ishibashi M, Mataki Y, Ootsuka T, Nomoto M, Hayashi C, Horiguchi A, Higashi M, Tanimoto A
- Journal Title
  
  BMC Microbiol.
  
  Volume: 22 Issue: 1 Pages: 147-147
- DOI
  10.1186/s12866-022-02557-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06889, KAKENHI-PROJECT-21K07222
[Journal Article] Sequential evaluation of MUC promoter methylation using next-generation sequencing-based custom-made panels in liquid-based cytology specimens of pancreatic cancer.2022
- Author(s)
  Yokoyama S, Iwaya H, Akahane T, Hamada T, Higashi M, Hashimoto S, Tanoue S, Ohtsuka T, Ido A, Tanimoto A
- Journal Title
  
  Diagn Cytopathol.
  
  Volume: 50 Issue: 11 Pages: 499-507
- DOI
  10.1002/dc.25022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06889, KAKENHI-PROJECT-21K07222, KAKENHI-PROJECT-20H03753
[Journal Article] Circulating microRNA Panel as a Potential Novel Biomarker for Oral Squamous Cell Carcinoma Diagnosis2021
- Author(s)
  Kodai Nakamura, Naomi Hiyake, Tomofumi Hamada, Seiya Yokoyama, Kazuki Mori, Kouta Yamashiro, Mahiro Beppu, Yasuaki Sagara, Yoshiaki Sagara, Tsuyoshi Sugiura
- Journal Title
  
  Cancers
  
  Volume: 13(3) Issue: 3 Pages: 449-449
- DOI
  10.3390/cancers13030449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10362, KAKENHI-PROJECT-18H03006, KAKENHI-PROJECT-17K17280, KAKENHI-PROJECT-21H03143
[Journal Article] PCP4/PEP19 downregulates neurite outgrowth via transcriptional regulation of Ascl1 and NeuroD1 expression in human neuroblastoma M17 cells2020
- Author(s)
  Kitazono Ikumi、Hamada Taiji、Yoshimura Takuya、Kirishima Mari、Yokoyama Seiya、Akahane Toshiaki、Tanimoto Akihide
- Journal Title
  
  Laboratory Investigation
  
  Volume: 100 Issue: 12 Pages: 1551-1563
- DOI
  10.1038/s41374-020-0462-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07018, KAKENHI-PROJECT-18K07326
[Journal Article] Next-generation sequencing analysis of endometrial screening liquid-based cytology specimens: a comparative study to tissue specimens2020
- Author(s)
  Akahane Toshiaki、Kitazono Ikumi、Yanazume Shintaro、Kamio Masaki、Togami Shinichi、Sakamoto Ippei、Nohara Sachio、Yokoyama Seiya、Kobayashi Hiroaki、Hiraki Tsubasa、Suzuki Shinsuke、Ueno Shinichi、Tanimoto Akihide
- Journal Title
  
  BMC Medical Genomics
  
  Volume: 13 Issue: 1 Pages: 101-101
- DOI
  10.1186/s12920-020-00753-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07326
[Journal Article] Predicted Prognosis of Pancreatic Cancer Patients by Machine Learning.2020
- Author(s)
  Seiya Yokoyama, Taiji Hamada, Michiyo Higashi, Kei Matsuo, Kousei Maemura, Hiroshi Kurahara, Michiko Horinouchi, Tsubasa Hiraki, Tomoyuki Sugimoto, Toshiaki Akahane, Suguru Yonezawa, Marko Kornmann, Surinder K Batra, Michael A Hollingsworth, Akihide Tanimoto
- Journal Title
  
  Clinical cancer research
  
  Volume: - Issue: 10 Pages: 2411-2421
- DOI
  10.1158/1078-0432.ccr-19-1247
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07326, KAKENHI-PROJECT-17K00054, KAKENHI-PROJECT-18K07019
[Journal Article] A tailored next‐generation sequencing panel identified distinct subtypes of wildtype IDH and TERT promoter glioblastomas2020
- Author(s)
  Higa Nayuta、Akahane Toshiaki、Yokoyama Seiya、Yonezawa Hajime、Uchida Hiroyuki、Takajo Tomoko、Kirishima Mari、Hamada Taiji、Matsuo Kei、Fujio Shingo、Hanada Tomoko、Hosoyama Hiroshi、Yonenaga Masanori、Sakamoto Akihisa、Hiraki Tsubasa、Tanimoto Akihide、Yoshimoto Koji
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 10 Pages: 3902-3911
- DOI
  10.1111/cas.14597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07326
[Journal Article] Comprehensive validation of liquid-based cytology specimens for next-generation sequencing in cancer genome analysis.2019
- Author(s)
  Akahane T, Yamaguchi T, Kato Y, Yokoyama S, Hamada T, Nishida Y, Higashi M, Nishihara H, Suzuki S, Ueno S, Tanimoto A.
- Journal Title
  
  PloS one.
  
  Volume: 14 Issue: 6 Pages: 0217724-0217724
- DOI
  10.1371/journal.pone.0217724
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07019
[Journal Article] PCP4/PEP19 upregulates aromatase gene expression via CYP19A1 promoter I.1 in human breast cancer SK-BR-3 cells2018
- Author(s)
  Honjo Kie、Hamada Taiji、Yoshimura Takuya、Yokoyama Seiya、Yamada Sohsuke、Tan Yan-Qin、Leung Lai K.、Nakamura Norifumi、Ohi Yasuyo、Higashi Michiyo、Tanimoto Akihide
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 51 Pages: 29619-29633
- DOI
  10.18632/oncotarget.25651
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07018, KAKENHI-PROJECT-18K07019
[Journal Article] TET1-mediated DNA hypomethylation regulates the expression of MUC4 in lung cancer2017
- Author(s)
  Yokoyama, S. Higashi, M. Tsutsumida, H. Wakimoto, J. Hamada, T. Wiest, E. Matsuo, K. Kitazono, I. Goto, Y. Guo, X. Hamada, T. Yamada, S. Hiraki, T. Yonezawa, S. Batra, S. K. Hollingsworth, M. A. Tanimoto, A.
- Journal Title
  
  Genes & cancer
  
  Volume: 8 Issue: 3-4 Pages: 517-527
- DOI
  10.18632/genesandcancer.139
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-15K11297, KAKENHI-PROJECT-15K21247
[Journal Article] Immunohistochemical expression of mucin antigens in gallbladder adenocarcinoma: MUC1-positive and MUC2-negative expression Is associated with vessel invasion and shortened survival.2017
- Author(s)
  Hiraki T, Yamada S, Higashi M, Hatanaka K, Yokoyama S, Kitazono I, Goto Y, Kirishima M, Batra SK, Yonezawa S, Tanimoto A
- Journal Title
  
  HISTOLOGY & HISTOPATHOLOGY
  
  Volume: 32(6) Pages: 585-596
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21247
[Journal Article] Immunohistochemical expression of mucin antigens in gallbladder adenocarcinoma: MUC1-positive and MUC2-negative expression Is associated with vessel invasion and shortened survival2017
- Author(s)
  Hiraki, T. Yamada, S. Higashi, M. Hatanaka, K. Yokoyama, S. Kitazono, I. Goto, Y. Kirishima, M. Batra, S. K. Yonezawa, S. Tanimoto, A.
- Journal Title
  
  Histol Histopathol
  
  Volume: 32 Pages: 585-596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08349
[Journal Article] Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC12017
- Author(s)
  Atsushi Matsuda, Michiyo Higashi, Tomomi Nakagawa, Seiya Yokoyama, Atsushi Kuno, Suguru Yonezawa, and Hisashi Narimatsu
- Journal Title
  
  Laboratory Investigation
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08349
[Journal Article] Assessment of tumor characteristics based on glycoform analysis of membrane-tethered MUC12017
- Author(s)
  Matsuda, A. Higashi, M. Nakagawa, T. Yokoyama, S. Kuno, A. Yonezawa, S. Narimatsu, H.
- Journal Title
  
  Lab Invest
  
  Volume: 97 Issue: 9 Pages: 1103-1113
- DOI
  10.1038/labinvest.2017.53
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-15K21247, KAKENHI-PROJECT-15K21667
[Journal Article] Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas2016
- Author(s)
  Yokoyama, S. Higashi, M. Kitamoto, S. Oeldorf, M. Knippschild, U. Kornmann, M. Maemura, K. Kurahara, H. Wiest, E. Hamada, T. Kitazono, I. Goto, Y. Tasaki, T. Hiraki, T. Hatanaka, K. Mataki, Y. Taguchi, H. Hashimoto, S. Batra, S. K. Tanimoto, A. Yonezawa, S. Hollingsworth, M. A.
- Journal Title
  
  Oncotarget
  
  Volume: - Issue: 27 Pages: 42553-42565
- DOI
  10.18632/oncotarget.9924
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-15K21247, KAKENHI-PROJECT-15H05045
[Journal Article] Mucin expression in endoscopic ultrasound-guided fine-needle aspiration specimens is a useful prognostic factor in pancreatic ductal adenocarcinoma2015
- Author(s)
  Michiyo Higashi, Seiya Yokoyama, Takafumi Yamamoto, Yuko Goto, Ikumi Kitazono, Tsubasa Hiraki, Hiroki Taguchi, Shinichi Hashimoto, Yoshihiko Fukukura, Chihaya Koriyama, Yuko Mataki, Kosei Maemura, Hiroyuki Shinchi, Maneesh Jain, Surinder K. Batra, Suguru Yonezawa
- Journal Title
  
  Pancreas
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26290048
[Journal Article] 新規DNAメチル化解析法の開発と応用2015
- Author(s)
  横山勢也、北本祥、山田宗茂、東美智代、米澤傑
- Journal Title
  
  化学工業
  
  Volume: 66 Pages: 28-33
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590447
[Journal Article] Mucin expression in endoscopic ultrasound-guided fine-needle aspiration specimens is a useful prognostic factor in pancreatic ductal adenocarcinoma.2015
- Author(s)
  Higashi M, Yokoyama S, Yamamoto T, Goto Y, Kitazono I, Hiraki T, et al.
- Journal Title
  
  Pancreas
  
  Volume: 44 Issue: 5 Pages: 728-34
- DOI
  10.1097/mpa.0000000000000362
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08349, KAKENHI-PROJECT-26462068, KAKENHI-PROJECT-15K21247
[Journal Article] 新規DNAメチル化解析法の開発と応用2015
- Author(s)
  横山　勢也、北本　祥、山田　宗茂、東　美智代、米澤　傑
- Journal Title
  
  化学工業
  
  Volume: 66 Pages: 28-33
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26290048
[Journal Article] Pathobiological implications of mucin (MUC) expression in the outcome of small bowel cancer2014
- Author(s)
  Shibahara H, Higashi M, Koriyama C, Yokoyama S, Kitazono I, Yasuhiro K, Narita M, Kuze S, Takanori K, Mita S, Arai T, Kato T, Yuasa N, Yamaguchi R, Kubota H, Suzuki H, Baba S, Rousseau K, Batra S K, Yonezawa S
- Journal Title
  
  PLoS ONE
  
  Volume: 9(4) Issue: 4 Pages: e86111-e86111
- DOI
  10.1371/journal.pone.0086111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] A comprehensive expression analysis of mucins in appendiceal carcinoma in a multicenter study: MUC3 is a novel prognostic factor2014
- Author(s)
  Shibahara, H. Higashi, M. Yokoyama, S. Rousseau, K. Kitazono, I. Osako, M. Shirahama, H. Tashiro, Y. Kurumiya, Y. Narita, M. Kuze, S. Hasagawa, H. et al.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 12 Pages: e115613-e115613
- DOI
  10.1371/journal.pone.0115613
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-26290048
[Journal Article] Diagnosis of pancreatic neoplasms using a novel method of DNA methylation analysis of mucin expression in pancreatic juice2014
- Author(s)
  Yokoyama S, Kitamoto S, Higashi M, Goto Y, Hara T, Ikebe D, Yamaguchi T, Arisaka Y, Niihara, Nishimata H, Tanaka S, Takaori K, Batra S K, Yonezawa S
- Journal Title
  
  PLoS ONE
  
  Volume: 9(4) Issue: 4 Pages: e93760-e93760
- DOI
  10.1371/journal.pone.0093760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] 特集　胆膵病理II:胆膵共通のトピックス【胆膵共通疾患とトピックス】膵胆道腫瘍におけるMUC発現．2013
- Author(s)
  米澤　傑、東美智代、横山勢也、後藤優子、北島信一
- Journal Title
  
  病理と臨床
  
  Volume: 31 Pages: 399-408
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] 特集：粘液産生性胆道系腫瘍の再出発－エビデンスとしての画像と病理　「胆道系腫瘍における粘液産生の組織学的側面」.2013
- Author(s)
  東美智代、柴原弘明、後藤優子、平木　翼、横山勢也、米澤　傑
- Journal Title
  
  胆と膵
  
  Volume: 34(5) Pages: 353-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24701008
[Journal Article] 胆道系腫瘍における粘液産生の組織学的側面2013
- Author(s)
  東美智代、柴原弘明、後藤優子、平木翼、横山勢也、米澤傑
- Journal Title
  
  胆と膵
  
  Volume: 34 Pages: 353-358
- Data Source
  KAKENHI-PROJECT-24590447
[Journal Article] 胆膵共通疾患とトピックス　膵胆道腫瘍におけるMUC発現2013
- Author(s)
  米澤傑、東美智代、横山勢也、後藤優子、北島信一
- Journal Title
  
  病理と臨床
  
  Volume: 31 Pages: 399-408
- Data Source
  KAKENHI-PROJECT-24590447
[Journal Article] 特集　胆膵病理II:胆膵共通のトピックス【胆膵共通疾患とトピックス】膵胆道腫瘍におけるMUC発現．2013
- Author(s)
  米澤　傑、東美智代、横山勢也、後藤優子、北島信一
- Journal Title
  
  病理と臨床
  
  Volume: 31(4) Pages: 399-408
- Data Source
  KAKENHI-PROJECT-24701008
[Journal Article] 特集　胆膵病理II:胆膵共通のトピックス【胆膵共通疾患とトピックス】膵胆道腫瘍におけるMUC発現2013
- Author(s)
  米澤　傑、東美智代、横山勢也、後藤優子、　北島信一
- Journal Title
  
  病理と臨床
  
  Volume: 31 Pages: 399-408
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] Identification of mucins by using a method involving a combination of on-membrane chemical deglycosylation and immunostaining2013
- Author(s)
  Matsuno YK, Dong W, Yokoyama S, Yonezawa S, Narimatsu H, Kameyama A
- Journal Title
  
  J Immunol Methods
  
  Volume: 394 Issue: 1-2 Pages: 125-130
- DOI
  10.1016/j.jim.2013.06.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310154, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24701008
[Journal Article] MUC4 and MUC1 Expression in Adenocarcinoma of the Stomach Correlates with Vessel Invasion and Lymph Node Metastasis : An Immunohisto chemical Study of Early Gastric Cancer.2013
- Author(s)
  Yukihiro Tamura, Michiyo Higashi, Sho Kitamoto, Seiya Yokoyama, Masahiko Osako, Michiko Horinouchi, Takeshi Shimizu, Mineo Tabata, Surinder K. Batra, Masamichi Goto, Suguru Yonezawa
- Journal Title
  
  PLoS ONE
  
  Volume: (in press) Issue: 11 Pages: e49251-e49251
- DOI
  10.1371/journal.pone.0049251
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] Expression of MUC4 mucin is observed mainly in the intestinal-type of intraductal papillary mucinous neoplasm of the pancreas2013
- Author(s)
  Kitazono I, Higashi M, Kitamoto S, Yokoyama S, Horinouchi M, Osako M, Shimizu T, Tabata M, Batra S K, Goto M, Yonezawa S
- Journal Title
  
  Pancreas
  
  Volume: 42(7) Issue: 7 Pages: 1120-1128
- DOI
  10.1097/mpa.0b013e3182965915
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors2013
- Author(s)
  Sho Kitamoto, Soiya Yokoyama, Michiyo Higashi, Norishlge Yamada, Sonshin Takao, Suguru Yonezawa
- Journal Title
  
  Oncogene
  
  Volume: 32(39) Issue: 39 Pages: 4614-4621
- DOI
  10.1038/onc.2012.478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] 特集：粘液産生性胆道系腫瘍の再出発－エビデンスとしての画像と病理　「２．胆道系腫瘍における粘液産生の組織学的側面」2013
- Author(s)
  東美智代、柴原弘明、後藤優子、平木　翼、　横山勢也、米澤　傑
- Journal Title
  
  胆と膵
  
  Volume: 34
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] 特集胆膵病理II : 胆膵共通のトピックス【胆膵共通疾患とトピックス】膵胆道腫瘍におけるMUC発現2013
- Author(s)
  米澤傑、東美智代、横山勢也、後藤優子、北島信一
- Journal Title
  
  病理と臨床
  
  Volume: 31(4) Pages: 399-408
- Data Source
  KAKENHI-PROJECT-24701008
[Journal Article] 特集：粘液産生性胆道系腫瘍の再出発－エビデンスとしての画像と病理　「胆道系腫瘍における粘液産生の組織学的側面」.2013
- Author(s)
  東美智代、柴原弘明、後藤優子、平木　翼、横山勢也、米澤　傑
- Journal Title
  
  胆と膵
  
  Volume: 34 Pages: 353-358
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] 特集 : 粘液産生性胆道系腫瘍の再出発-エビデンスとしての画像と病理「胆道系腫瘍における粘液産生の組織学的側面」2013
- Author(s)
  東美智代、柴原弘明、後藤優子、平木翼、横山勢也、米澤傑
- Journal Title
  
  胆と膵
  
  Volume: 34(5) Pages: 353-358
- Data Source
  KAKENHI-PROJECT-24701008
[Journal Article] 胆管内乳頭状腫瘍(IPNB) : 粘液,MUC発現からのアプローチ2012
- Author(s)
  東美智代、横山勢也、北本祥、米澤傑
- Journal Title
  
  肝胆膵
  
  Volume: 65(3) Pages: 487-494
- Data Source
  KAKENHI-PROJECT-24701008
[Journal Article] The application of Methylation specific electrophoresis(MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells2012
- Author(s)
  Yokoyama S, Kitamoto S, Yamada N, Houjou I, Sugai T, Nakamura S, Arisaka Y, Takaori K, Higashi M, Yonezawa S.
- Journal Title
  
  BMC Cancer
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399
[Journal Article] The application of Methylation specific electrophoresis (MSE) to DNA methylation analysis of the 5' CpG island of mucin in cancer cells2012
- Author(s)
  Seiya Yokoyama
- Journal Title
  
  BMC Cancer
  
  Volume: 12(In press) Issue: 1 Pages: 67-67
- DOI
  10.1186/1471-2407-12-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-22590317, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] Pathobiological Implications of MUC16/CA125 Expression in Intrahepatic Cholangiocarcinoma-Mass Forming Type2012
- Author(s)
  Higashi M, Yamada N, Yokoyama S, Kitamoto S, Tabata K, Koriyama C, Batra SK, Yonezawa S.
- Journal Title
  
  Pathobiology
  
  Volume: 79巻 Pages: 101-106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399
[Journal Article] Pathobiological implications of expression of MUC16/CA125 in intrahepatic cholangiocarcinoma-mass formina type2012
- Author(s)
  Michiyo Higashi
- Journal Title
  
  Pathobiology
  
  Volume: 79 Issue: 2 Pages: 101-106
- DOI
  10.1159/000335164
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] 癌におけるムチンの臨床病理学的意義および診断への応用-難治性膵胆管癌の早期診断に向けて-2012
- Author(s)
  米澤傑、東美智代、横山勢也、北本祥、山田宗茂
- Journal Title
  
  MEDICAL TECNOLOGY
  
  Volume: 40(4) Pages: 419-425
- Data Source
  KAKENHI-PROJECT-24701008
[Journal Article] Expression of MUC17 Is Regulated by HIF1α-mediated Hypoxic Responses and Requires a Methylation-free Hypoxia Responsible Element in Pancreatic Cancer.2012
- Author(s)
  Sho Kitamoto, Seiya Yokoyama, Michiyo Higashi, Norishige Yamada, Shyuichiro Matsubara, Sonshin Takao, Surinder K. Batra, Suguru Yonezawa
- Journal Title
  
  PLoS ONE
  
  Volume: 7(9) Issue: 9 Pages: e44108-e44108
- DOI
  10.1371/journal.pone.0044108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24701008
[Journal Article] A novel anti-MUC1 antibody against the MUC1 cytoplasmic tail domain : use in sensitive identification of poorly differentiated cells in adenocarcinoma of the stomach2012
- Author(s)
  Suguru Yonezawa
- Journal Title
  
  Gastric Cancer
  
  Volume: (In press) Issue: 4 Pages: 370-381
- DOI
  10.1007/s10120-011-0125-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085, KAKENHI-PROJECT-24590447, KAKENHI-PROJECT-24701008
[Journal Article] 癌におけるムチンの臨床病理学的意義および診断への応用　－難治性膵胆管癌の早期診断に向けて－2012
- Author(s)
  米澤　傑、東美智代、横山勢也、北本　祥、　山田宗茂
- Journal Title
  
  MEDICAL TECNOLOGY
  
  Volume: 40 Pages: 419-425
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] 胆管内乳頭状腫瘍(IPNB)：粘液，MUC発現からのアプローチ2012
- Author(s)
  東美智代、横山勢也、北本　祥、米澤　傑
- Journal Title
  
  肝胆膵
  
  Volume: 65 Pages: 487-494
- Data Source
  KAKENHI-PROJECT-23390085
[Journal Article] Epigenetic regulation of mucin genes in human cancers2011
- Author(s)
  Norishige Yamada
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 2 Issue: 2 Pages: 85-96
- DOI
  10.1007/s13148-011-0037-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085
[Journal Article] Improved method for immunostaining of mucin separated by supported molecular matrix electrophoresis by optimizing the matrix composition and fixation procedure2011
- Author(s)
  Matsuno Y., et al
- Journal Title
  
  Electrophoresis
  
  Volume: 32 Issue: 14 Pages: 1829-1836
- DOI
  10.1002/elps.201000608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23310154, KAKENHI-PROJECT-23390085
[Journal Article] DNA methylation and histone H3-K9 modifications contribute to MUC17 expression2011
- Author(s)
  Kitamoto S, Yamada N, Yokoyama S, Houjou I, Higashi M, Goto M, Batra SK, Yonezawa S.
- Journal Title
  
  Glycobiology
  
  Volume: 21巻 Pages: 247-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399
[Journal Article] Mucins in human neoplasms : Clinical pathology, gene expression and diagnostic application2011
- Author(s)
  Suguru Yonezawa
- Journal Title
  
  Pathology International
  
  Volume: 61 Issue: 12 Pages: 697-716
- DOI
  10.1111/j.1440-1827.2011.02734.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J09349, KAKENHI-PROJECT-21590399, KAKENHI-PROJECT-23390085
[Journal Article] Expression of MUC5AC, an early marker of pancreatobiliary cancer, is regulated by DNA methylation in the distal promoter region in cancer cells2010
- Author(s)
  Yamada N, Nishida Y, Yokoyama S, Tsutsumida H, Houjou I, Kitamoto S, Goto M, Higashi M, and Yonezawa S.
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 17巻 Pages: 844-54
- NAID
  10027664155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399
[Journal Article] Significance of mucin expression in pancreatobiliary neoplasms2010
- Author(s)
  Yonezawa S, Higashi M, Yamada N, Yokoyama S, Goto M.
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 17巻 Pages: 108-24
- NAID
  10027662473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399
[Journal Article] Promoter hypomethylation contributes to the expression of MUC3A in cancer cells2010
- Author(s)
  Kitamoto S, Yamada N, Yokoyama S, Houjou I, Higashi M, Yonezawa S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 397巻 Pages: 333-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590399
[Patent] 癌の判定装置、癌の情報取得方法及びプログラム2022
- Inventor(s)
  横山勢也、東美智代、谷本昭英
- Industrial Property Rights Holder
  横山勢也、東美智代、谷本昭英
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-21K06889
[Patent] METHOD FOR DIAGNOSING TYPE OF PANCREATIC TUMOR2012
- Inventor(s)
  横山勢也、米澤傑、北本祥
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-29
- Overseas
- Data Source
  KAKENHI-PROJECT-24701008
[Patent] METHOD FOR DIAGNOSING TYPE OF PANCREATIC TUMOR2012
- Inventor(s)
  横山勢也, 米澤傑, 北本祥
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Rights Type
  特許
- Filing Date
  2012-06-29
- Overseas
- Data Source
  KAKENHI-PROJECT-23390085
[Patent] NOVEL DNA METHYLATION ANALYSIS METHOD2011
- Inventor(s)
  横山勢也, 米澤傑
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-04-21
- Overseas
- Data Source
  KAKENHI-PROJECT-23390085
[Patent] NOVEL DNA METHYLATION ANALYSIS METHOD2011
- Inventor(s)
  横山勢也、米澤傑
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Rights Type
  特許
- Filing Date
  2011-04-21
- Overseas
- Data Source
  KAKENHI-PROJECT-24701008
[Patent] 新規なDNAメチル化解析方法2010
- Inventor(s)
  横山勢也、米澤傑
- Industrial Property Number
  2010-098163
- Filing Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21590399
[Patent] 新規なDNAメチル化解析方法2010
- Inventor(s)
  横山勢也, 米澤傑
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Number
  2010-098163
- Filing Date
  2010-04-21
- Data Source
  KAKENHI-PROJECT-21590399
[Presentation] DNAメチル化解析による胆管癌術後予後予測手法の構築2023
- Author(s)
  横山勢也、東美智代、谷本昭英
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-21K06889
[Presentation] Construction of prognosis prediction method for after surgery of Cholangiocarcinoma using aberrant methylation status2022
- Author(s)
  Seiya Yokoyama
- Organizer
  16th Mucins in Health and Disease
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07222
[Presentation] 局所内進展にとどまる胆嚢癌におけるムチン発現の検討2022
- Author(s)
  能美昌子, 東美智代, 横山勢也, 谷本昭英, 瀧口翔也, 薮田愛, 利光鏡太郎, 井戸弘毅
- Organizer
  日本外科学会定期学術集会
- Data Source
  KAKENHI-PROJECT-21K06889
[Presentation] DNAメチル化解析による胆管癌術後予後予測手法の構築2022
- Author(s)
  横山勢也, 霧島茉莉, 東美智代
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-21K06889
[Presentation] DNAメチル化解析による胆管癌術後予後予測手法の構築2022
- Author(s)
  横山勢也
- Organizer
  日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K07222
[Presentation] 膵胆管系癌と胆嚢中微生物叢との関連2021
- Author(s)
  横山勢也、霧島茉莉、東美智代
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-21K06889
[Presentation] DNAメチル化解析結果を用いた計算機科学による膵癌予後予測2021
- Author(s)
  横山勢也、東美智代、谷本昭英
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07019
[Presentation] 胆道・膵臓腫瘍の遺伝子異常と病理診断　胆道・膵腫瘍の早期診断とバイオマーカー2020
- Author(s)
  東美智代, 横山勢也, 平木翼, 北薗育美, 霧島茉莉, 田中貴子, 濱田一正, 堀之内道子, 米澤傑, 谷本昭英
- Organizer
  日本病理学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07019
[Presentation] DNAメチル化解析結果を用いた計算機科学による膵癌予後予測2019
- Author(s)
  横山勢也，東美智代，谷本昭英
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K07326
[Presentation] 胆管癌におけるDNAメチル化解析2019
- Author(s)
  横山勢也，東美智代，谷本昭英
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18K07326
[Presentation] DNAメチル化解析結果を用いた計算機科学による膵癌予後予測2019
- Author(s)
  横山勢也，東美智代，谷本昭英
- Organizer
  第4回黒潮カンファレンス
- Data Source
  KAKENHI-PROJECT-18K07326
[Presentation] Predicted Prognosis of Pancreatic Cancer Patients by Machine Learning.2019
- Author(s)
  横山勢也東美智代, 谷本昭英
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07019
[Presentation] MUC1およびMUC4遺伝子のメチル化解析による膵癌摘出術後の予後評価2018
- Author(s)
  横山勢也，東美智代，谷本昭英
- Organizer
  日本病理学会
- Data Source
  KAKENHI-PROJECT-18K07326
[Presentation] MUC1およびMUC4遺伝子のメチル化解析による膵癌摘出術後の予後評価2018
- Author(s)
  横山勢也, 東美智代, 谷本昭英
- Organizer
  日本病理学会
- Data Source
  KAKENHI-PROJECT-18K07019
[Presentation] PDAC摘出術後におけるムチン遺伝子のメチル化解析を用いた予後予測法の構築2018
- Author(s)
  横山勢也, 東美智代, 谷本昭英
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-18K07019
[Presentation] PDAC摘出術後におけるムチン遺伝子のメチル化解析を用いた予後予測法の構築2018
- Author(s)
  横山勢也，東美智代，谷本昭英
- Organizer
  日本癌学会学
- Data Source
  KAKENHI-PROJECT-18K07326
[Presentation] Analysis of Mucin expression and DNA methylation in serous adenoma of the pancreas2016
- Author(s)
  Michiyo Higashi, Seiya Yokoyama, Tsubasa Hiraki , Ikumi Kitazono, Yuko Goto,Tasaki Takashi, Mari Kirishima, Kazuhito Hatanaka, and Akihide Tanimoto
- Organizer
  日本病理学会第105回総会
- Place of Presentation
  仙台国際センター(宮城県仙台市)
- Year and Date
  2016-05-12
- Data Source
  KAKENHI-PROJECT-15K08349
[Presentation] ムチン発現からみたIPMNの悪性度2015
- Author(s)
  東美智代、横山勢也、北薗育美、後藤優子、田崎貴嗣、平木翼、畑中一仁、蔵原弘、又木雄弘、前村公成、新地洋之、谷本昭英、米澤傑、夏越祥次
- Organizer
  外科病理学会
- Place of Presentation
  ホテルアパローム紀ノ国(和歌山県和歌山市)
- Year and Date
  2015-11-06
- Invited
- Data Source
  KAKENHI-PROJECT-15K08349
[Presentation] TET1 was important factor for DNA demethylation to regulate the expression of MUC1 and MUC4 in lung cancer.2014
- Author(s)
  Seiya Yokoyama, Sho Kitamoto, Hideaki Tsutsumida, Joji Wakimoto, Michiyo Higashi, Suguru Yonezawa
- Organizer
  23rd Biennial EACR Congress
- Place of Presentation
  International Congress Centre Munich (München, Germany)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] TET1 was important factor for DNA demethylation to regulate the expression of MUC1 and MUC4 in lung cancer.2014
- Author(s)
  Seiya Yokoyama, Sho Kitamoto, Hideaki Tsutsumida, Joji Wakimoto, Michiyo Higashi, Suguru Yonezawa
- Organizer
  23rd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  International Congress Center Munich (Munchen, Germany)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary, and pulmonary neoplasms2013
- Author(s)
  Suguru Yonezawa, Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi
- Organizer
  MUCINS IN HEALTH AND DISEASE (12th International Workshop on Carcinoma-associated Mucins)
- Place of Presentation
  Robinson College (Cambridge, UK)
- Data Source
  KAKENHI-PROJECT-24590447
[Presentation] Examination of mucin expression including a novel DNA methylation analysis method (MSE): Its application for diagnosis of human pancreatic neoplasms.2013
- Author(s)
  Yonezawa S, Yokoyama S, Goto Y, Higashi M
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  William Willis Hall (Kagoshima, Japan)
- Invited
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary and pulmonary neoplasms2013
- Author(s)
  Suguru Yonezawa, Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi
- Organizer
  MUCINS IN HEALTH AND DISEASE (12th International Workshop on Carcinoma-associated Mucins)
- Place of Presentation
  King's College (London, UK)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] 膵癌におけるMUC1遺伝子のメチル化ステータスとmRNA発現解析2013
- Author(s)
  横山勢也、北本　祥、堤田英明、脇本譲二、東美智代、米澤　傑
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌　（北海道）
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] 肺癌におけるMUC1遺伝子のメチル化ステータスとmRNA発現解析2013
- Author(s)
  横山勢也、北本祥、堤田英明、脇本譲二、東美智代、米澤傑
- Organizer
  第102回日本病理学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary and pulmonary neoplasms2013
- Author(s)
  Yonezawa S, Yokoyama S, Kitamoto S, Higashi M
- Organizer
  MUCINS IN HEALTH AND DISEASE (12th International Workshop on Carcinoma-associated Mucins)
- Place of Presentation
  Robinson College (Cambridge, UK)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary and pulmonary neoplasms, MUCINS IN HEALTH AND DISEASE2013
- Author(s)
  Yonezawa S, Yokoyama S, Kitamoto S, Higashi M
- Organizer
  12th International Workshop on Carcinoma-associated Mucins
- Place of Presentation
  Robinson College (Cambridge, UK)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] Diagnosis of pancreatic neoplasms by application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic juice2013
- Author(s)
  Suguru Yonezawa, Seiya Yokoyama, Michiyo Higashi, Yuko Goto, Shinichi Kitajima
- Organizer
  Worldwide Innovate Networking in personalized cancer medicine
- Place of Presentation
  Le Palais des Congred (Paris, France)
- Data Source
  KAKENHI-PROJECT-24590447
[Presentation] Examination of mucin expression including a novel DNA methylation analysis method (MSE) : Its application for diagnosis of human pancreatic neoplasms2013
- Author(s)
  Yonezawa S, Yokoyama S, Goto Y, Higashi M
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  William Willis Hall (Kagoshima, Japan)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] DNA promoter methylation status and mRNA expression of MUC1 in human lung cancer2013
- Author(s)
  Seiya Yokoyama, Sho Kitamoto, Hideyuki Tsutsumida, Jyouji Wakimoto, Michiyo Higashi, Suguru Yonezawa
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  鹿児島市
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] 膵癌におけるMUC1遺伝子のメチル化ステータスとmRNA発現解析2013
- Author(s)
  横山勢也、北本　祥、堤田英明、脇本譲二、東美智代、米澤　傑
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌　（札幌市）
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Diagnosis of pancreatic neoplasms by a novel high sensitive DNA methylation analysis method “MSE”for pancreatic juices2013
- Author(s)
  米澤傑、横山勢也、東美智代
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] 浸潤性膵癌におけるEUS-FNABでのムチン発現2013
- Author(s)
  東　美智代、横山勢也、後藤優子、平木　翼、後藤正道、米澤　傑
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌　（札幌市）
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] DNA promoter methylation status and mRNA expression status of MUC1 in lung cancer2013
- Author(s)
  横山勢也、北本祥、堤田英明、東美智代、米澤傑
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜　神奈川県横浜市
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Diagnosis of pancreatic neoplasms by application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic juices2013
- Author(s)
  Yonezawa S, Yokoyama S, Higashi M, Goto Y, Kitajima S
- Organizer
  Worldwide Innovative Networking in personalized cancer medicine
- Place of Presentation
  Le Palais des Congres (Paris, France)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Diagnosis of pancreatic neoplasms by application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic juices2013
- Author(s)
  Yonezawa Suguru, Yokoyama Seiya, Higashi Michiyo, Goto Yuko, Kitajima Shinichi
- Organizer
  Worldwide Innovative Networking in personalized cancer medicine
- Place of Presentation
  "Le Palais des Congres (Paris, FRANCE)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Diagnosis of pancreatic neoplasms by application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic juices.2013
- Author(s)
  Yonezawa Suguru,Yokoyama Seiya, Higashi Michiyo, Goto Yuko, Kitajima Shinichi
- Organizer
  Worldwide Innovative Networking in personalized cancer medicine
- Place of Presentation
  Le Palais des Congres (Paris, France)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] 膵癌におけるMUC1遺伝子のメチル化ステータスとmRNA発現解析2013
- Author(s)
  横山勢也、北本祥、堤田英明、脇本譲二、東美智代、米澤傑
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌(北海道)
- Data Source
  KAKENHI-PROJECT-24590447
[Presentation] 浸潤性膵管癌におけるEUS-FNABでのムチン発現2013
- Author(s)
  東美智代、横山勢也、後藤優子、平木翼、後藤正道、米澤傑
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌(北海道)
- Data Source
  KAKENHI-PROJECT-24590447
[Presentation] 新しい高感度DNAメチル化高感度検出法(MSE法)を用いた膵液中のムチン発現遺伝子解析による膵腫瘍の診断2013
- Author(s)
  米澤　傑、東美智代、横山勢也、後藤優子、平木　翼、北島信一、原　太郎、有坂好史、新原　亨、高折恭一
- Organizer
  第30回日本胆膵病態・生理研究会
- Place of Presentation
  ウエスティンホテル仙台　（宮城）
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] DNA promoter methylation status and mRNA expression of MUC1 in human lung cancer2013
- Author(s)
  Yokoyama S, Kitamoto S, Tsutsumida H, Wakimoto J, Higashi M, Yonezawa S
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  William Willis Hall (Kagoshima, Japan)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] Application of a novel DNA methylation analysis method (MSE) for mucin expression in pancreatic, biliary and pulmonary neoplasms2013
- Author(s)
  Suguru Yonezawa,Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi
- Organizer
  MUCINS IN HEALTH AND DISEASE (12th International Workshop on Carcinoma-associated Mucins)
- Place of Presentation
  Robionson College (Cambridge, UK)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] 膵癌におけるMUC17の低酸素応答メカニズムの解明2012
- Author(s)
  北本　祥、横山勢也、東　美智代、米澤　傑
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  京王プラザホテル　(東京)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] 新規高感度DNAメチル化解析法（MSE法）による膵IPMN亜型の早期診断へ向けた応用2012
- Author(s)
  横山勢也、北本　祥、東美智代、米澤　傑
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  京王プラザホテル　(東京)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] The application of new DNA methylation analysis, designated methylation specific electrophoresis (MSE) for pancreatic juice analysis.2012
- Author(s)
  Yokoyama S, kitamoto S, Hara T, Arisaka Y, Takaori K, Yamamoto T, Niihara T, Nishimata H, Tanaka S, Higashi M, Yonezawa S
- Organizer
  International Symposium on Pancreas Cancer 2012
- Place of Presentation
  京都国際コンベンションセンター（京都)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] 新規高感度DNAメチル化解析法（MSE法）による膵IPMN亜型の早期診断へ向けた応用2012
- Author(s)
  横山勢也、北本祥、北条いづみ、東美智代、米澤傑
- Organizer
  第101回日本病理学会学術総会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] 膵内分泌腫瘍におけるMUC17発現の検討2012
- Author(s)
  東美智代、北本祥、横山勢也、田畑和宏、北薗育美、平木翼、米澤傑
- Organizer
  日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24590447
[Presentation] MUC1 enhances hypoxia-driven angiogenesis through the regulation of multiple proangiogenic factors.2012
- Author(s)
  Kitamoto S, Yokoyama S, Higashi M, Yamada N, Takao S, Yonezawa S
- Organizer
  International Symposium on Pancreas Cancer 2012
- Place of Presentation
  京都国際コンベンションセンター（京都)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] TET1 was important factor for DNA demethylation to regulate the expression of MUC1 and MUC4 in lung cancer2012
- Author(s)
  Yokoyama S, Kitamoto S, Tsutsumida H, Wakimoto J, Higashi M, Yonezawa S
- Organizer
  23^<rd> Biennial Ccongress of the European Association for Cancer Research
- Place of Presentation
  International Congress Center Munich (Munchen, Germany) (発表確定)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] CTGF is enhanced by hypoxia through nuclear recruitment of MUC1 in pancreatic cancer.2012
- Author(s)
  Kitamoto S, Higashi M, Yokoyama S, Takao S, Yonezawa S
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  バルセロナ国際会議場（Barcelona, Spain ）
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] CTGF is enhanced by hypoxia through nuclear recruitment of MUC1 in pancreatic cancer2012
- Author(s)
  Kitamoto S, Higashi M, Yokoyama S, Takao S, Yonezawa S
- Organizer
  22nd Biennial Congress of the European Association for Cancer Research
- Place of Presentation
  バルセロナ国際会議場(Barcelona, Spain)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] 膵内分泌腫瘍におけるMUC17発現の検討2012
- Author(s)
  東美智代、北本　祥、横山勢也、田畑和宏、　　　北薗育美、平木　翼、米澤　傑
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  京王プラザホテル　(東京)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] DNA promoter methylation status and mRNA expression of MUC1 in human bile duct cancer2012
- Author(s)
  Seiya Yokoyama, Sho Kitamoto, Michiyo Higashi, Suguru Yonezawa
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] 胃癌細胞(por2、sig)の検出に有用な新しいモノクローナル抗体｢MUC1-014E｣（第2報）：生検標本への応用2012
- Author(s)
  米澤　傑、北島信一、東美智代、堀之内道子、横山勢也、北本　祥、田村幸大、清水　健、　　　　後藤正道
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  京王プラザホテル　(東京)
- Data Source
  KAKENHI-PROJECT-23390085
[Presentation] MUC1 Enhances Hypoxia-Driven Angiogenesis Through the Regulation of Multiple Proangiogenic Factors2012
- Author(s)
  Kitamoto S, Yokoyama S, Higashi M, Yamada N, Takao S, Yonezawa S
- Place of Presentation
  京都国際コンベンションセンター(京都)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] The Application of New DNA Methylation Analysis, Designated Methylation Specific Electrophoresis (MSE) for Pancreatic Juice Analysis2012
- Author(s)
  Yokoyama S, kitamoto S, Hara T, Arisaka Y, Takaori K, Yamamoto T, Niihara T, Nishimata H, Tanaka S, Higashi M, Yonezawa S
- Place of Presentation
  京都国際コンベンションセンター(京都)
- Data Source
  KAKENHI-PROJECT-24701008
[Presentation] The novel method of DNA methylation status analysis2010
- Author(s)
  Yokoyama, S., et al.
- Organizer
  第56回日本病理学会秋期特別総会
- Place of Presentation
  北九州国際会議場(北九州市)
- Data Source
  KAKENHI-PROJECT-21590399
[Presentation] 新しい高感度DNAメチル化高感度検出法(MSE法)を用いた膵液中のムチン発現遺伝子解析による膵腫瘍の診断
- Author(s)
  米澤　傑、東美智代、横山勢也、後藤優子、平木　翼、北島信一、原　太郎、有坂好史、新原　亨、高折恭一
- Organizer
  第30回日本胆膵病態・生理研究会
- Place of Presentation
  ウエスティンホテル仙台　（仙台市）
- Data Source
  KAKENHI-PROJECT-24701008

1. HIGASHI Michiyo (60315405)

# of Collaborated Projects: 11 results

# of Collaborated Products: 70 results
2. 谷本昭英 (10217151)

# of Collaborated Projects: 11 results

# of Collaborated Products: 11 results
3. Hamada Taiji (30771480)

# of Collaborated Projects: 8 results

# of Collaborated Products: 3 results
4. 赤羽俊章 (70754480)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. YONEZAWA Suguru (10175002)

# of Collaborated Projects: 4 results

# of Collaborated Products: 42 results
6. 比嘉那優大 (90792200)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. Hamada Tomofumi (00444894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
8. Yamada Norisige (60625242)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 杉浦剛 (40322292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. 中村康大 (90783506)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
11. 杉本知之 (70324829)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 古川龍彦 (40219100)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. GOTO Masamichi (80325779)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. SHINCHI Hiroyuki (60284874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NARIMATSU Hisashi (40129581)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KAMEYAMA Akihiko (80415661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
17. 原太郎 (20535869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 河野憲司 (50214664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 飛田陽 (10435026)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中村利明 (60381183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 野口紘嗣 (60782901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 霧島茉莉 (10899967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 花谷亮典 (60304424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 米澤大 (50550076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 大槻純男 (60323036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MATSUO KEI

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. MATSUNO Yu-ki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

YOKOYAMA Seiya 横山 勢也

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機械学習を用いた胆管癌悪性度予測モデルの構築Principal Investigator

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Construction of DNA Methylation Markers for liqid biopsy of Pancreatic Cancer.Principal Investigator

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A fundamental study for construction of bile duct cancer early diagnosis method by DNA methylation analysis.Principal Investigator

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YOKOYAMA Seiya 横山勢也

[Book] 胆と膵 IPMN大全　IPMNの歴史的変遷　IPMNにおけるMUC発現とその評価の歴史2020

[Book] 病理診断に役立つ分子生物学(病理と臨床臨時増刊号 Vol.29) (分担執筆), 第 2 部病理診断医になじみのある疾患関連分子, MUC 解説編. (金井弥栄, 石川俊平, 池田栄二;編集)2011

[Book] 病理診断に役立つ分子生物学(病理と臨床臨時増刊号 Vol.29) (分担執筆), 第 2 部病理診断医になじみのある疾患関連分子, MUC 診断編. (金井弥栄, 石川俊平, 池田栄二;編集)2011