FURUKAWA Tatsuhiko 古川龍彦

Researcher Number	40219100
Other IDs
External Links
Affiliation (Current)	2022: 鹿児島大学, 医歯学総合研究科, 客員研究員
Affiliation (based on the past Project Information) *help	2021: 鹿児島大学, 医歯学域医学系, 客員研究員 2016 – 2021: 鹿児島大学, 医歯学域医学系, 教授 2017: 鹿児島大学, 医学部, 教授 2012: 鹿児島大学, 医歯(薬)学総合研究科, 教授 2010 – 2012: 鹿児島大学, 医歯学総合研究科, 教授 … More 2010 – 2012: 鹿児島大学, 大学院・医歯学総合研究科, 教授 2010: 鹿児島大学, 医歯学総合研究科, 准教授 2007 – 2009: 鹿児島大学, 大学院・医歯学総合研究科, 准教授 2005 – 2006: 鹿児島大学, 大学院医歯学総合研究科, 助教授 2003 – 2005: Kagoshima University, Graduate School of Medical and Dental Sciences, Associate Professor, 大学院・医歯学総合研究科, 助教授 2002: 鹿児島大学, 医学部, 助教授 1995 – 2001: Kagoshima University, Faculty of Medicine, Research Associate, 医学部, 助手 1999: Kagoshima University, Faculty of Medicine, Research Associate, 医学部・腫瘍研究施設, 助手 1990 – 1991: 鹿児島大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Biological Sciences / Clinical oncology / Biophysics / Pathological medical chemistry / Tumor biology / Medium-sized Section 50:Oncology and related fields / Basic Section 50010:Tumor biology-related Except Principal Investigator Pathological medical chemistry / Biological Sciences … More / Living organism molecular science / General medical chemistry / Science and Engineering / Risk sciences of radiation/Chemicals / Fisheries chemistry / Cerebral neurosurgery / Urology / Pathological medical chemistry / Risk sciences of radiation and chemicals / Basic Section 53050:Dermatology-related Less
Keywords	Principal Investigator 抗がん剤耐性 / MRP1 / ABC transporter / BHLHE41 / 肺がん / オートファジー / 多剤耐性 / チミジンホスホリラーゼ / アポトーシス / 血管新生 … More / 抗癌剤耐性 / ATP7A / CD45 / LAR / LTC4 / グルタチオン / LTC_4 / photoaffinity labeling / Glutathione / Nucleotide binding domain / SN-38 / 遺伝子増幅 / コピー数変化 / コピー数 / 薬剤耐性 / がん抑制遺伝子 / ゲノム不安定性 / 細胞死 / MRP / グルタチオン抱合体ポンプ / 低酸素 / フルオロウリジン / 銅トランスポータ / シスプラチン / PタイプATPase / Rab 蛋白質 / 薬剤輸送体 / 小胞輸送 / ＡＴＰ７Ａ / Gタンパク質 / Rabタンパク質 / ATP7B / Rab蛋白質 / チロシンホスファターゼ / T細胞 / CD3ζ / インスリンレセプター / CD35 / CD3 / LCK / ZAP70 / tyrosine phosphatase / T cell / CD3zeta / insulin receptor / 2デオキシDリボース / 2デオキシLリボース / ノックアウトマウス / MNGIE / 白質脳症 / thymidine phosphorylase / 2deoxy-D-ribose / 2deoxy-I-ribose / angipgenesis / apoptosis / hypoxia / metastasis / knock-out mouse / 光親和性誘導体 / ABCトランスポータ / ヌクレオチド結合ドメイン / トリプシン切断部分 / 抗癌剤 / glutathione / nucleotide binding domain / trypsin digestion sites / 光親和性標識 / トリプシン切断断片 / 細胞室内ドメイン / ATPase / トランスゴルジネットワーク / 大腸癌 / 基質認識 / ABCトランスポーター / tryptic Fragment / RRM1 / コピー数変異 / ゲノムj / 遺伝子コピー数変化 / 遺伝子修復 / エピゲノム制御 / BAX / オートファジ― / ゲノム / 腫瘍発生 … More Except Principal Investigator MRP / チミジンホスホリラーゼ / 血管新生 / 2-deoxy-D-ribose / 2-deoxy-L-ribose / TPI / アポトーシス / Thymidine phosphorylase / GS-X pump / 多剤耐性 / シスプラチン耐性 / 不定型多剤耐性 / 耐性克服 / ロイコトリエンC_4 / PAK-104P / 肺扁平上皮癌 / 低酸素 / 転移 / Apoptosis / metastasis / angiogenesis / ノックアウトマウス / thymidine phosphorylase / TSP-1 / 耐性 / Cisplatin-resistance / ATL / cMOAT / VEGF / Cyclooxygenase / ABCB6 / resistance / cisplatin / arsenite / mitochondria / MRP1 / signature sequence / GSH / Pー糖蛋白質 / 薬剤結合部位 / 副腎 / セファランチン / PAKー104P / BSO / ジーンターゲテイング / 浸潤 / BN1P3 / HIF-1α / Thymidine_phosphorylase / invasion / 腫瘍増殖 / 2-デオキシ-D-リボース / 2-デオキシ-L-リボース / エクジソン / 内分泌攪乱物質 / 昆虫 / IL-8 / ROS / NFκB / 5-FU / Thymidine phosphorylase (TP) / NADPHオキシダーゼTegafur / GBL / 血管新生阻害効果 / TP / NF-κB / IKKα / β / IkB / HIF-1 / BNIP3 / 5-Fu / マイクロDNA / 線維芽細胞 / thymdine phosphorylase / drug resistance / apoptosis / 5FU / TSP1 / EGR1 / c-myc / fibroblast / MMP-9 / PI3K / Akt / p38 / Arsenite / survivin / 内因性血管新生阻害因子 / プロモーター活性化 / thrombospondin-1 / ヒト齊帯静脈血管内皮細胞 / 腫瘍血管新生 / オミックス / エコトキシコロジー / カワウ / ゼブラフィッシュ / ダイオキシン / ニワトリ / マイクロシスチンLR / p53 / 肝毒性 / 発がん / OATP1B1 / OATP1B3 / 化学予防 / マイクロシスチン / セラミド / ナリンジン / トランスポーター / 肝臓毒 / 天然化合物 / カルボキシルエステラーゼ / アオコ / 細胞増殖 / pifithrin-α / 血管新生抑制 / 天然物 / 海洋天然物 / 血管新生阻害 / 海綿 / 膠芽腫 / temozolomide / MLH1 / ABC トランスポーター / glioblastoma / temozolomide resistance / DEC2 / 薬剤耐性 / 多剤耐性克服 / PAKー200 / アドリアマイシン耐性 / Atypical multidrug-resistant mutants / Adriamycin resistance / Cisplatin resistance / dihydropyridine analogue / PAK-200 / Reversal of multidrug resistance / GS-X ポンプ / 重金属 / ロイコトリエンC4 / GS-Xポンプ / Leukotriene C4 / 移行上皮癌 / Squamous cell carcinoma / TCC / PAK-104p / Bladder Cancer / Metanestine / testicnlan tamors / Renal cell carcimoma / Bladden Cancer / thyomidine phosphorylase / testicular tumor / Renal cell carcinoma / Biadden Cancer / Metastasis / Glxcoprotein / Glxcopsotein / Bladder cancer / Metanestin / Testicular tumor / Renal cell carcinima / アトポーシス / デオキシリボース / PD-ECGF / チトクロームC / PDーECGF / チミジン / 2-depxy-D-ribose / hypoxia / apotosis / ヒ素 / シスプラチン / ABCトランスポーター / ABCトランスポータ / フイリマングース / 水銀 / 肝臓 / HiCEP解析 / 水銀代謝 / 水銀蓄積 / CD147/Basigin / 乾癬 / T細胞分化 / Th17細胞 / モノカルボン酸トランスポーター / AP-9 / 解糖系 / MCT Less

Mechanisms analysis of lung cancer suppression and cell death by an autophagy inducible gene BHLHE41.Principal Investigator
- Principal Investigator
  
  古川龍彦
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kagoshima University
CD147/basiginを標的とした乾癬の新規治療の開発
- Principal Investigator
  
  金蔵拓郎
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kagoshima University
Approach to regulatory mechanism of copy number variation the gene amplified.Principal Investigator
- Principal Investigator
  
  Tatsuhiko Furukawa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 50:Oncology and related fields
- Research Institution
  Kagoshima University
Evaluation of moleclar bases for suppression of gene amplificationPrincipal Investigator
- Principal Investigator
  
  Furukawa Tatsuhiko
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kagoshima University
Identify and database creation of gene expression related mercury in liver of the small Indian mongoose using HiCEP analysis
- Principal Investigator
  
  Horai Sawako
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Tottori University
Analysis of cooperative functions of transporters andvesicle transport system in efflux of anticancer agentsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Tatsuhiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Clinical oncology
- Research Institution
  Kagoshima University
Exploring of regulatory substances ofTSP-1, an endogenous inhibitor of angiogenesis
- Principal Investigator
  
  IWAGAWA Tetsuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kagoshima University
Elucidation of temozolomide resistance mechanism which is not involved in MGMT in malignant glioma
- Principal Investigator
  
  YASHIRO Kazutaka
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Kagoshima University
Large-scale differential display system with vertebrate-common degenerate oligonucleotide primers
- Principal Investigator
  
  TERAOKA Hiroki
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Rakuno Gakuen University
Chemoprevention for the microcystin-LR poisoning by natural compounds
- Principal Investigator
  
  KOMATSU Masaharu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Fisheries chemistry
- Research Institution
  Kagoshima University
Search of natural compound activating endogenous anti-angiogenesis factor as an anti-cancer agent.
- Principal Investigator
  
  AOKI Shunji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Hyogo University of Health Sciences
Molecular targeting agents that suppress invasion and metastasis of cancer cells
- Principal Investigator
  
  AKIYAMA Shinichi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
Nano-scale analysis of the drug transport mechanism of MRP1Principal Investigator
- Principal Investigator
  
  FURUKAWA Tatsuhiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Search and analysis of genes involved in the sensitivity to arsenic trioxide of human cells.
- Principal Investigator
  
  AKIYAMA Shin-ichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
銅トランスポータATP7A・ATP7Bによる抗癌剤耐性の分子機構の解析Principal Investigator
- Principal Investigator
  
  古川龍彦
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
Analysis of substrates transport mechanism and structural modification of MRP1Principal Investigator
- Principal Investigator
  
  FURUKAWA Tatsuhiko
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
昆虫を指標にした内分泌攪乱物質の環境評価
- Principal Investigator
  
  竹内亨
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Science and Engineering
- Research Institution
  Kagoshima University
腫瘍増殖・浸潤・転移を抑制する新規薬剤の開発
- Principal Investigator
  
  秋山伸一
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kagoshima University
Analysis of the mechanisms for biological activities of thymidine phosphorylasePrincipal Investigator
- Principal Investigator
  
  FURUKAWA Tatsuhiko
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
チミジンホスホリラーゼのがん血管新生とアポトーシスへの関与
- Principal Investigator
  
  秋山伸一
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kagoshima University
Physiological function of thymidine phosphorylase and the involvement of the enzyme in tumor growth
- Principal Investigator
  
  AKIYAMA Shinichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
チミジンホスホリラーゼ阻害剤による腫瘍増殖抑制とその基礎的研究Principal Investigator
- Principal Investigator
  
  古川龍彦
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
BASIC AND CLINICOPATHOLOGICAL ANALYSIS FOR MOLECULES REGULATING INVASIVE AND METASTATIC PROPERTIES OF GENITOURINARY TUMORS
- Principal Investigator
  
  SHIRAHAMA Tsutomu
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  Kagoshima University
Identification and analysis of tyrosine phosphatase CD45 interacting proteinsPrincipal Investigator
- Principal Investigator
  
  FURUKAWA Tatsuhiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Kagoshima University
チミジンホスホリラーゼの血管新生活性の機構とその他の生理活性
- Principal Investigator
  
  原口みさ子
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Analysis of structure and function of GS-X pumps.
- Principal Investigator
  
  AKIYAMA Shin-ichi
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagoshima University
MRPの機能と臨床での多剤耐性の関与およびその克服
- Principal Investigator
  
  秋山伸一
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
MRPの薬剤輸送機能とイオンチャネル活性の解折Principal Investigator
- Principal Investigator
  
  古川龍彦
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kagoshima University
Structure and function of an active efflux pump for cisplatin
- Principal Investigator
  
  AKIYAMA Shinichi
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Pー糖蛋白質の関与しない多剤耐性の分子機構の解明と克服方法の開発
- Principal Investigator
  
  秋山伸一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Kagoshima University
Pー糖蛋白質の構造と機能の研究
- Principal Investigator
  
  AKIYAMA Shinichi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kagoshima University
Isolation and analysis of atypical multidrug-resistant mutants.
- Principal Investigator
  
  AKIYAMA Shin-ichi
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  Kagoshima University

[Book] A case study of intact vitellogenin isolated from the plasma of wild silver Japanese eel(Anguilla japonica)2010
- Author(s)
  M. Komatsu, S. Ando, S. Hayashi, T. Furukawa, S. Takumi, K. Aoyama, and T. Takeuchi
- Publisher
  Nova Science Publishers, Inc
- Data Source
  KAKENHI-PROJECT-21580250
[Book] A case study of intact vitellogenin isolated from the plasma of wild silver Japanese eel (Anguilla japonica). Jackson E.Rathbond ed.Handbook of Lipoprotein Research.2010
- Author(s)
  Masaharu Komatsu, Seiichi Ando, Seiichi Hayashi, Tatsuhiko Furukawa, Shota Takumi, Kohji Aoyama, Toru Takeuchi
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-21580250
[Journal Article] Development of a highly sensitive method for the quantitative analysis of modified nucleosides using UHPLC-UniSpray-MS/MS.2021
- Author(s)
  Kogaki T, Ohshio I, Ura H, Iyama S, Kitae K, Morie T, Fujii S, Sato S, Nagata T, Takeda AH, Aoki M, Ueda K, Minami K, Yamamoto M, Kawahara K, Furukawa T, Sato M, Ueda Y, Jingushi K, Tozuka Z, Saigusa D, Hase H, Tsujikawa K.
- Journal Title
  
  Journal of pharmaceutical and biomedical analysis
  
  Volume: 197 Pages: 113943-113943
- DOI
  10.1016/j.jpba.2021.113943
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-20K08209, KAKENHI-PROJECT-21K06691
[Journal Article] Cancer type-SLCO1B3 promotes epithelial-mesenchymal transition resulting in the tumour progression of non-small cell lung cancer2021
- Author(s)
  Hase H, Aoki M, Matsumoto K, Nakai S, Nagata T, Takeda A, Ueda K, Minami K, Kitae K, Jingushi K, Ueda Y, Yamamoto M, Furukawa T, Sato M, Tsujikawa K.
- Journal Title
  
  Oncology reports
  
  Volume: 45 Pages: 309-316
- DOI
  10.3892/or.2020.7839
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248
[Journal Article] Formin-like 1 (FMNL1) Is Associated with Glioblastoma Multiforme Mesenchymal Subtype and Independently Predicts Poor Prognosis.2020
- Author(s)
  Higa N, Shinsato Y, Kamil M, Hirano T, Takajo T, Shimokawa M, Minami K, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K and Arita K
- Journal Title
  
  Int J Mol Sci
  
  Volume: 20 Pages: 6355-63
- DOI
  10.3390/ijms20246355
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-18K16590, KAKENHI-PROJECT-16H06276
[Journal Article] FARP1 boosts CDC42 activity from integrin αvβ5 signaling and correlates with poor prognosis of advanced gastric cancer.2020
- Author(s)
  Hirano T, Shinsato Y, Tanabe K, Higa N, Kamil M, Kawahara K, Furukawa T & Shoji Natsugoe, et al.
- Journal Title
  
  Oncogenesis
  
  Volume: 9 Pages: 13-13
- DOI
  10.1038/s41389-020-0190-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16H06276
[Journal Article] Involvement of ribosomal protein L11 expression in sensitivity of gastric cancer against 5-FU2020
- Author(s)
  Kawahata T, Kawahara K, Shimokawa M, Sakiyama A, Shiraishi T, Minami K, Yamamoto M, Shinsato Y, Arima K, Hamada T, Furukawa T
- Journal Title
  
  ONCOLOGY LETTERS
  
  Volume: 19 Pages: 2258-2264
- DOI
  10.3892/ol.2020.11352
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K06732, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-17J05291, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16H06276
[Journal Article] MicroRNA-130b functions as an oncomiRNA in non-small cell lung cancer by targeting tissue inhibitor of metalloproteinase-2.2019
- Author(s)
  Hirono T, Jingushi K, Nagata T, Sato M, Minami K, Aoki M, Takeda AH, Umehara T, Egawa H, Nakatsuji Y, Kitae K, Ueda Y, Hase H, Yamamoto M, Shinsato Y, Kawahara K, Furukawa T, Tsujikawa K.
- Journal Title
  
  SCIENTIFIC REPORTS
  
  Volume: 9 Pages: 1-1
- DOI
  10.1038/s41598-019-43355-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-17H04125, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-17K10796
[Journal Article] チミジン異化経路を介したがん細胞の低栄養抵抗性と悪性化2019
- Author(s)
  古川龍彦，田畑　祥，曽我朋義
- Journal Title
  
  生化学
  
  Volume: 91 Pages: 50-57
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme.2019
- Author(s)
  Kamil M, Shinsato Y, Higa N, Hirano T, Idogawa M, Takajo T, Minami K, Shimokawa M, Yamamoto M, Kawahara K, Yonezawa H, Hirano H, Furukawa T, Yoshimoto K, Arita K.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 120 Pages: 819-826
- DOI
  10.1038/s41416-019-0413-x
- Description
  Epub ahead of print
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17K10871, KAKENHI-PROJECT-19K08372, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16K09285
[Journal Article] Oral aversion to dietary sugar, ethanol and glycerol correlates with alterations in specific hepatic metabolites in a mouse model of human citrin deficiency2019
- Author(s)
  Saheki T, Inoue K, Ono H, Fujimoto Y, Furuie S, Yamamura KI, Kuroda E, Ushikai M, Asakawa A, Inui A, Eto K, Kadowaki T, Moriyama M, Sinasac DS, Yamamoto T, Furukawa T, Kobayashi K.
- Journal Title
  
  Mol Ther.
  
  Volume: 120 Pages: 1242-1251
- DOI
  10.1016/j.ymgme.2017.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450447, KAKENHI-PROJECT-15K01623, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-15K09595, KAKENHI-PROJECT-19K22566
[Journal Article] 5-Aza-2-deoxycytidine Enhances the Sensitivity of 5-Fluorouracil by Demethylation of the Thymidine Phosphorylase Promoter2019
- Author(s)
  Nishizawa Y, Ikeda R, Yamamoto M, Kawahara K, Shinsato Y, Minami K, Nitta M. Terazono H, Akiyama S, Furukawa T, Takeda Y
- Journal Title
  
  Anticancer Res
  
  Volume: 39 Pages: 4129-4136
- DOI
  10.21873/anticanres.13571
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-18K06788, KAKENHI-PROJECT-19K22566, KAKENHI-PROJECT-18K15248, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16H06276
[Journal Article] Pivotal role of inter-organ aspartate metabolism for treatment of mitochondrial aspartate-glutamate carrier 2 (citrin) deficiency, based on the mouse model.2019
- Author(s)
  Saheki T, Moriyama M, Kuroda E, Funahashi A, Yasuda I, Setogawa Y, Gao Q, Ushikai M, Furuie S, Yamamura KI, Takano K, Nakamura Y, Eto K, Kadowaki T, Sinasac DS, Furukawa T, Horiuchi M, Tai YH.
- Journal Title
  
  Sci. Rep.
  
  Volume: 9 (1) Pages: 4179-4179
- DOI
  10.1038/s41598-019-39627-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05999, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-26000012
[Journal Article] mRNA Therapy Improves Metabolic and Behavioral Abnormalities in a Murine Model of Citrin Deficiency.2019
- Author(s)
  Cao J, An D, Galduroz M, Zhuo J, Liang S, Eybye M, Frassetto A, Kuroda E, Funahashi A, Santana J, Mihai C, Benenato KE, Kumarasinghe ES, Sabnis S, Salerno T, Coughlan K, Miracco EJ, Levy B, Besin G, Schultz J, Lukacs C, Guey L, Finn P, Furukawa T, Giangrande PH, Saheki T, Martini PGV.
- Journal Title
  
  Mol Ther.
  
  Volume: 27 Pages: 1242-1251
- DOI
  10.1016/j.ymthe.2019.04.017
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] The histone deacetylase inhibitor LBH589 inhibits undifferentiated pleomorphic sarcoma growth via downregulation of FOS-like antigen 1.2019
- Author(s)
  Saitoh Y, Bureta C, Sasaki H, Nagano S, Maeda S, Furukawa T, Taniguchi N, Setoguchi T.
- Journal Title
  
  Mol Carcinog.
  
  Volume: 58(2) Pages: 234-246
- DOI
  10.1002/mc.22922
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10868, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-17K10973
[Journal Article] A novel isolation method for cancer prognostic factors via the p53 pathway by a combination of in vitro and in silico analyses2018
- Author(s)
  Yohey Kamijo, Kohichi Kawahara, Takuma Yoshinaga, Hiroyuki Kurata, Kazunari Arima, Tatsuhiko Furukawa
- Journal Title
  
  Oncoscience
  
  Volume: 印刷中
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] ATP7B expression in human glioblastoma is related with temozolomide resistance.2018
- Author(s)
  Moinuddin FM, Hirano H, Shinsato Y, Higa N, Arita K, Furukawa T.
- Journal Title
  
  Oncology letter
  
  Volume: 14 Pages: 7777-7782
- DOI
  10.3892/ol.2017.7249
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-15K10338
[Journal Article] Thymidine phosphorylase in cancer aggressiveness and chemoresistance.2018
- Author(s)
  Furukawa T, Tabata S, Yamamoto M, Kawahara K, Shinsato Y, Minami K, Shimokawa M, Akiyama SI.
- Journal Title
  
  Pharmacol Res.
  
  Volume: 28 Pages: 15-20
- DOI
  10.1016/j.phrs.2018.03.019
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-18K15248
[Journal Article] Thymidine catabolism promotes NADPH oxidase-derived reactive oxygen species (ROS) signalling in KB and yumoto cells2018
- Author(s)
  Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Toyoda Y, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama S
- Journal Title
  
  Scientific Reports
  
  Volume: 印刷中
- NAID
  120006875668
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma2017
- Author(s)
  Tabata S, Yamamoto M, Goto H, Hirayama A, Ohishi M, Kuramoto T, Mitsuhashi A, Ikeda R, Haraguchi M, Kawahara K, Shinsato Y, Minami K, Saijo A, Hanibuchi M, Nishioka Y, Sone S, Esumi H, Tomita M, Soga T, Furukawa T, Akiyama SI
- Journal Title
  
  Cell Report
  
  Volume: 19 Pages: 1313-1321
- DOI
  10.1016/j.celrep.2017.04.061
- NAID
  120007001420
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460201, KAKENHI-PROJECT-17K07221, KAKENHI-PROJECT-16K21361, KAKENHI-PROJECT-16H05309, KAKENHI-PROJECT-16K14619, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-15K21364, KAKENHI-PROJECT-16K07121
[Journal Article] Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.2017
- Author(s)
  Tanabe K, Shinsato Y, Furukawa T, Kita Y, Hatanaka K, Minami K, Kawahara K, Yamamoto M, Baba K, Mori S, Uchikado Y, Maemura K, Tanimoto A, Natsugoe S.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 6353-6363
- DOI
  10.18632/oncotarget.14087
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293306, KAKENHI-PROJECT-26670160, KAKENHI-PROJECT-15K10108, KAKENHI-PROJECT-16K10510, KAKENHI-PROJECT-15K18413, KAKENHI-PROJECT-16K07121
[Journal Article] Inhibition of casein kinase 2 prevents growth of human osteosarcoma.2017
- Author(s)
  Takahashi K, Setoguchi T, Tsuru A, Saitoh Y, Nagano S, Ishidou Y, Maeda S, Furukawa T, Komiya S.
- Journal Title
  
  Oncology Report
  
  Volume: 37 Pages: 1141-1147
- DOI
  10.3892/or.2016.5310
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10452, KAKENHI-PROJECT-16K07121
[Journal Article] Overexpression of carboxylesterase contributes to the attenuation of cyanotoxin microcystin-LR toxicity2017
- Author(s)
  Shota Takumi, Tai Shimono, Satoshi Ikema, Yuki Hotta, Petros Kingstone Chigwechokha, Kazuhiro Shiozaki, Yasumasa Sugiyama, Mitsuru Hashimoto, Tatsuhiko Furukawa, Masaharu Komatsu
- Journal Title
  
  Comp Biochem Physiol C Toxicol Pharmacol.
  
  Volume: 194 Pages: 22-27
- DOI
  10.1016/j.cbpc.2017.01.008
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07875, KAKENHI-PROJECT-16K07876, KAKENHI-PROJECT-26860445, KAKENHI-PROJECT-16K07121, KAKENHI-PROJECT-16K09115
[Journal Article] ATP7B expression confers multidrug resistance through drug sequestration2016
- Author(s)
  Moinuddin FM, Shinsato Y, Komatsu M, Mitsuo R, Minami K, Yamamoto M, Kawahara K, Hirano H, Arita K, Furukawa T.
- Journal Title
  
  Oncotarget.
  
  Volume: 7 Pages: 22779-90
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07121
[Journal Article] Snail modulates cell metabolism in MDCK cells.2013
- Author(s)
  Haraguchi M, Indo HP, Iwasaki Y, Iwashita Y, Fukushige T, Majima HJ, Izumo K, Horiuchi M, Kanekura T, Furukawa T, Ozawa M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 432(4) Pages: 618-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] VEGF expression is augmented by hypoxia-induced PGIS in human fibroblasts2013
- Author(s)
  Wang J, Ikeda R, Che X-f, Ooyama A, Yamamoto M, Furukawa T, Hasui K, Zheng Cl, Tajitsu Y, Oka T, Tabata S, Nishizawa Y, Eizuru Y, Akiyama S
- Journal Title
  
  Int J Onc
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells2013
- Author(s)
  Tajitsu Y, Ikeda R, Nishizawa Y, Mataki H, Che XF, Sumizawa T, Nitta M, YamaguchT, Yamamoto M, Tabata S, Akiyama S, Yamada K, Furukawa T, Takeda Y
- Journal Title
  
  Int J of Mol Med
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose2013
- Author(s)
  Ikeda R, Tabata S, Tajitsu Y, Nishizawa Y, Minami K, Furukawa T, Yamamoto M, Shinsato Y, Akiyama S, Yamada K , Takeda Y.
- Journal Title
  
  Onc Rep
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] VEGF expression is augmented by hypoxia-induced PGIS in human fibroblasts.2013
- Author(s)
  Wang J, Ikeda R, Che XF, Ooyama A, Yamamoto M, Furukawa T, Hasui K, Zheng Cl, Tajitsu Y, Oka T, Tabata S, Nishizawa Y, Eizuru Y, Akiyama S
- Journal Title
  
  Int J Onc
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Ceramide aminoethylphosphonate from jumbo flying squid Dosidicus gigas attenuates the toxicity of cyanotoxin microcystin-LR2013
- Author(s)
  Komatsu M, Ichiyama N, Kurimoto T, Takumi S, Shiozaki K, Sugiyama Y, Furukawa T, Ando S, Itonori S, Saito H
- Journal Title
  
  Fish Sci
  
  Volume: 79 Pages: 313-320
- NAID
  10031138669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Snail modulates cell metabolism in MDCK cells2013
- Author(s)
  Haraguchi M, Indo HP, Iwasaki Y, Iwashita Y, Fukushige T, Majima HJ, Izumo K, Horiuchi M, Kanekura T, Furukawa T, Ozawa M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 432 Pages: 618-625
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Molecular basis for the regulation of hypoxia-inducible factor-1α levels by 2-deoxy-D-ribose.2013
- Author(s)
  Ikeda R, Tabata S, Tajitsu Y, Nishizawa Y, Minami K, Furukawa T, Yamamoto M, Shinsato Y, Akiyama S, Yamada K , Takeda Y
- Journal Title
  
  Onc Rep
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Enhanced intracellular drug delivery of pH-sensitive doxorubicin/poly(ethylene glycol)-block-poly- (4-vinylbenzylphosphonate) nanoparticles in multi-drug resistant human epidermoid KB carcinoma cells.2013
- Author(s)
  Kamimura M, Furukawa T, Akiyama S, Nagasaki Y
- Journal Title
  
  Biomater. Sci
  
  Volume: 1 Pages: 361-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Molecular basis for the expression of major vault protein induced by hyperosmotic stress in SW620 human colon cancer cells.2013
- Author(s)
  Tajitsu Y, Ikeda R, Nishizawa Y, Mataki H, Che XF, Sumizawa T, Nitta M, YamaguchT, Yamamoto M, Tabata S, Akiyama S, Yamada K, Furukawa T, Takeda Y
- Journal Title
  
  Int J of Mol Med
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Ceramide aminoethylphosphonate from jumbo flying squid Dosidicus gigas attenuates the toxicity of cyanotoxin microcystin-LR.2013
- Author(s)
  Komatsu M, Ichiyama N, Kurimoto T, Takumi S, Shiozaki K, Sugiyama Y, Furukawa T, Ando S, Itonori S, Saito H
- Journal Title
  
  Fish Sci
  
  Volume: 79 Pages: 313-320
- NAID
  10031138669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] CD147- targeting siRNA inhibits cell-matrix adhesion of human malignant melanoma cells by phosphorylating focal adhesion kinase2012
- Author(s)
  Nishibaba R, Higashi Y, Su J, Furukawa T, Kawai K, Kanekura T
- Journal Title
  
  J Dermatol
  
  Volume: 39 Pages: 63-67
- NAID
  10031184828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells2012
- Author(s)
  Tabata S, Ikeda R, Yamamoto M, Furukawa T, Kuramoto T, Takeda Y, Yamada K, Haraguchi M, Nishioka Y, Sone S, Akiyama S
- Journal Title
  
  Oncology Reports
  
  Volume: 28 Pages: 895-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT32012
- Author(s)
  Yue H, Tanaka K, Furukawa T, Karnik SS, Li W
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1823 Pages: 1316-1323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Enhanced intracellular drug delivery of pH-sensitive doxorubicin/poly(ethylene glycol)-block-poly- (4-vinylbenzylphosphonate) nanoparticles in multi-drug resistant human epidermoid KB carcinoma cells2012
- Author(s)
  Kamimura M, Furukawa T, Akiyama S, Nagasaki Y
- Journal Title
  
  Biomater. Sci
  
  Volume: 1 Pages: 361-367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Thymidine phosphorylase enhances reactive oxygen species generation and interleukin-8 expression in human cancer cells.2012
- Author(s)
  Tabata S, Ikeda R, Yamamoto M, Furukawa T, Kuramoto T, Takeda Y, Yamada K, Haraguchi M, Nishioka Y, Sone S, Akiyama S
- Journal Title
  
  Oncology Reports
  
  Volume: 28(3) Pages: 895-902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT32012
- Author(s)
  Yue H, Tanaka K, Furukawa T, Karnik SS, Li W
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: 1823 (8) Pages: 1316-1323
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] CD147- targeting siRNA inhibits cell-matrix adhesion of human malignant melanoma cells by phosphorylating focal adhesion kinase2012
- Author(s)
  Nishibaba R, Higashi Y, Su J, Furukawa T, Kawai K, Kanekura T
- Journal Title
  
  J Dermatol
  
  Volume: 39(1) Pages: 63-67
- NAID
  10031184828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Cytotoxic eunicellin-type diterpenes from the soft coral liphyton viscudium2011
- Author(s)
  Iwagawa T, Kusatsu T, Tsuha K, Hamada T, Okamura H, Furukawa T, Akiyama S, Doe M, Morimoto Y, Iwase F, Takemurae K
- Journal Title
  
  Heterocycles
  
  Volume: 83 Pages: 2149-2155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Novel cytotoxic isolated from Jamaican Hyptis verticillata jacq induces apoptosis and overcomes multidrug resistance2011
- Author(s)
  White Y, Hamada T, Yoshimitsu M, Nakashima M, Hachiman M, Kozako T, Matsushita K, Uozumi K, Suzuki S, Kofune H, Furukawa T, Arima N
- Journal Title
  
  Anticancer Res
  
  Volume: 31(12) Pages: 4251-4257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Cytotoxic eunicellin-type diterpenes from the soft coral liphyton viscudium2011
- Author(s)
  Iwagawa T, Kusatsu T, Tsuha K, Hamada T, Okamura H, Furukawa T, Akiyama S, Doe M, Morimoto Y, Iwase F, Takemurae K
- Journal Title
  
  Heterocycles
  
  Volume: 83(9) Pages: 2149-2155
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Novel cytotoxic isolated from Jamaican Hyptis verticillata jacq induces apoptosis and overcomes multidrug resistance2011
- Author(s)
  White Y, Hamada T, Yoshimitsu M, Nakashima M, Hachiman M, Kozako T, Matsushita K, Uozumi K, Suzuki S, Kofune H, Furukawa T, Arima N
- Journal Title
  
  Anticancer Res
  
  Volume: 31 Pages: 251-4257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells2010
- Author(s)
  Matsushita S, Ikeda R, Nishizawa Y, Che XF, Furukawa T, Miyadera K, Tabata S, Ushiyama M, Tajitsu Y, Yamamoto M, Takeda Y, Minami K, Mataki H, Kanzaki T, Yamada K, Kanekura T, Akiyama S
- Journal Title
  
  Int J Oncol.
  
  Volume: 36 Pages: 1193-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-fluorouracil in human cancer carcinoma cells2010
- Author(s)
  Matsushita S, Ikeda R, Nishizawa Y, Che XF, Furukawa T, Miyadera K, Tabata S, Ushiyama M, Tajitsu Y, Yamamoto M, Takeda Y, Minami K, Mataki H, Kanzaki T, Yamada K, Kanekura T, Akiyama S
- Journal Title
  
  Int J Oncol
  
  Volume: 36(5) Pages: 1193-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] p53 Plays an Important Role in Cell Fate Determination after Exposure to Microcystin-LR2010
- Author(s)
  Takumi S, Komatsu M, Furukawa T, Ikeda R, Sumizawa T, Akenaga H, Maeda Y, Aoyama K, Arizono K, Ando S, Takeuchi T
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 118(9) Pages: 1292-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Cytotoxic Isomalabaricane Derivatives and a Monocyclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata2010
- Author(s)
  Hirashima M, Tsuda K, Hamada T, Okamura H, Furukawa T, Akiyama S, Tajitsu Y, Ikeda R, Komatsu M, Doe M, Morimoto Y, Shiro M, van Soest RW, Takemura K, Iwagawa T
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 73 Pages: 1512-1518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Cytotoxic Isomalabaricane Derivatives and a Monocytclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata.2010
- Author(s)
  Miyabi Hirashima, Kazuomi Tsuda, Toshiyuki Hamada, Hiroaki Okamura, Tatsuhiko Furukawa
- Journal Title
  
  Journal of Natural Products
  
  Volume: 73 Pages: 1512-1518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580250
[Journal Article] Cytotoxic Isomalabaricane Derivatives and a Monocyclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata2010
- Author(s)
  Hirashima M, Tsuda K, Hamada T, Okamura H, Furukawa T, Akiyama S, Tajitsu Y, Ikeda R, Komatsu M, Doe M, Morimoto Y, Shiro M, van Soest RW, Takemura K, Iwagawa T
- Journal Title
  
  J. Nat. Prod.
  
  Volume: 73(9) Pages: 1512-1518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] Cytotoxic Isomalabaricane Derivatives and a Monocytclic Triterpene Glycoside from the Sponge Rhabdastrella globostellata2010
- Author(s)
  M. Hirashima, K. Tsuda, T. Hamada, H. Okamura, T. Furukawa, S. Akiyama, Y. Tajitsu, R. Ikeda, M. Komatsu, M. Doe, Y. Morimoto, M. Shiro, R. W. M. van Soest, K. Takemura and T. Iwagawa
- Journal Title
  
  Journal of Natural Products
  
  Volume: 73 Pages: 1512-1518
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580250
[Journal Article] p53 Plays an Important Role in Cell Fate Determination after Exposure to Microcystin-LR2010
- Author(s)
  Takumi S, Komatsu M, Furukawa T, Ikeda R, Sumizawa T, Akenaga H, Maeda Y, AoyamaK, Arizono K, Ando S, Takeuchi T
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 118 Pages: 1292-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1α and reduces HIF-1α level in ACHN human renal adenocarcinoma cells2010
- Author(s)
  Iwashita K-I, Ikeda R, Takeda Y, Sumizawa T, Furukawa T, Yamaguchi T, Akiyama S, Yamada K
- Journal Title
  
  Cancer Science
  
  Volume: 100 Pages: 920-926
- NAID
  10026590870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510236
[Journal Article] Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1α and reduces HIF-1α level in ACHN human renal adenocarcinoma cells2010
- Author(s)
  Iwashita K-I, Ikeda R, Takeda Y, Sumizawa T, Furukawa T, Yamaguchi T, Akiyama S, Yamada K
- Journal Title
  
  Cancer Science
  
  Volume: 100(4) Pages: 920-926
- NAID
  10026590870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501047
[Journal Article] p53 plays an important role in cell fate determination after exposure to microcystin-LR.2010
- Author(s)
  Shota Takumi, Masaharu Komatsu, Tatsuhiko Furukawa, Ryuji Ikeda, Tomoyuki Sumizawa, Hitomi Akenaga, Yuta Maeda, Kohji Aoyama, Koji Arizono, Seiichi Ando, Toru Takeuchi
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 118 Pages: 1292-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580250
[Journal Article] p53 plays an important role in cell fate determination after exposure to microcystin-LR2010
- Author(s)
  S. Takumi, M. Komatsu, T. Furukawa, R. Ikeda, T. Sumizawa, H. Akenaga, Y. Maeda, K. Aoyama, K. Arizono, S. Ando, and T. Takeuchi
- Journal Title
  
  Environmental Health Perspectives
  
  Volume: 118 Pages: 1292-1298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580250
[Journal Article] Cepharanthine is a potent reversal agent for MRP7 (ABGG10)-mediated multidrug resistance.2009
- Author(s)
  Ying Zhou, Tatsuhiko Furukawa, Shin-ichi Akiyama, Zhe-Sheng Chen, (他9名8番目)
- Journal Title
  
  Biochem. Pharmacol. 77
  
  Pages: 993-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Thymidine phosphorylase inhibits the expression of proapoptic protein BNIP3. Biochem.2008
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama, Katsushi Yamada, (他11名15番目)
- Journal Title
  
  Biophys. Res. Commun. 370
  
  Pages: 220-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in KM12C cells.2008
- Author(s)
  Hong-Ye Zhao, Masatatsu Yamamoto, Tatsuhiko Furukawa, Michihiko Kuwano, Shin-ichi Akiyama, (他10名15番目)
- Journal Title
  
  Cancer Lett. 270
  
  Pages: 156-163
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Hyperosmotic stress up-regulates the expression of major vault protein in SW620 human colon cancer cells.2008
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Masatatsu Yamamoto, Katsushi Yamada, Shin-ichi Akiyama., (他14名19番目)
- Journal Title
  
  Exp. Cell Res. 314
  
  Pages: 3017-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Copper transport systems are involved in multidrug resistance and drug transport2008
- Author(s)
  Furukawa T
- Journal Title
  
  Curr Med Chem. 15
  
  Pages: 3268-3278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU.2008
- Author(s)
  Hong-Ye Zhao, Masatatsu Yamamoto, Tatsuhiko Furukawa, Michihiko Kuwano, Shin-ichi Akiyama, (他10名15番目)
- Journal Title
  
  Cancer Res. 68
  
  Pages: 7035-7041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Copper-transporting P-type ATPase, ATP7A, Confers Multidrug Resistance and its Expression is Related to Resistance to SN-38 in Clinical Colon Cancer.2007
- Author(s)
  Owatari S, Akune S, Komatsu M, Ikeda R, Firth SD, Che XF., Yamamoto M, Tsujikawa K, Kitazono M, Ishizawa T, Takeuchi T, Aikou T, Mercer FBJ, Akiyama S, Furukawa T.
- Journal Title
  
  Cancer Research 67(10)
  
  Pages: 4860-4868
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Involvement of Mitogen-Activated Protein Kinase Signaling Pathways in Microcystin-LR-Induced Apoptosis After its Selective Uptake Mediated by OATP1B1 and OATP1B32007
- Author(s)
  Komatsu M, Furukawa T, Ikeda R, Takumi S, Nong Q, Aoyama K, Akiyama S, Keppler D, Takeuchi T.
- Journal Title
  
  Toxicol Sciences 97(2)
  
  Pages: 407-416
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Copper-Transporting P-type ATPase, ATP7A, confers multidrug resistance and its expression is related to resistance to SN-38 in clinical colon cancer.2007
- Author(s)
  Saruski Owatari, Masatatsu Yamamoto, Shin-ichi Akiyama, Tatsuhiko Furukawa, (他11名14番目)
- Journal Title
  
  Cancer Res. 67
  
  Pages: 4860-4868
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Isolation and characterization of arsenite-resistant human epidermoid carcinoma KB cells.2007
- Author(s)
  Tokushi Tachiwada, Tatsuhiko Furukawa, Masatatsu Yamamoto, Masayuki Nakagawa, Shin-ichi Akiyama:, (他8名13番目)
- Journal Title
  
  Oncol. Rep. 8
  
  Pages: 721-727
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Involvement of mitogen-activated protein kinase signaling pathways in microcystin-LR-induced apoptosis after its selective uptake mediated by OATP1B1 and OATP1B3.2007
- Author(s)
  Masaharu Komatsu, Tatsuhiko Furukawa, Shin-ichi Akiyama, Toru Takeuchi., (他5名7番目)
- Journal Title
  
  Toxicol. Sci. 97
  
  Pages: 407-416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.2006
- Author(s)
  Kengo Tsuneyoshi, Tatsuhiko Furukawa, Shin-ichi Akiyama, Masayuki Nakagawa., (他6名9番目)
- Journal Title
  
  Cancer Lett. 244
  
  Pages: 239-246
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Overexpression of survivin in primary ATL cells and sodium arsenite induces apoptosis by down-regulating survivin expression in ATL cell lines.2006
- Author(s)
  Che XF., Zheng CL., Owatari, S., Mutoh M., Gotannda, T., Jeung HC, Furukawa T., Ikeda R., Yamamoto M., Haraguchi M., Arima N., Akiyama SI.
- Journal Title
  
  Blood 107(12)
  
  Pages: 4880-4887
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Direct activation of the human major vault protein gene by DNA-damaging agents.2006
- Author(s)
  Yuichi Shimamoto, Tatsuhiko Furukawa, Ryuzo Sakata, Shin-ichi Akiyama:, (他4名8番目)
- Journal Title
  
  Oncol Rep. 15
  
  Pages: 645-652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase.2006
- Author(s)
  Hei-Cheul Jeung, Tatsuhiko Furukawa, Shin-ichi Akiyama., (他10名13番目)
- Journal Title
  
  FEBS Lett. 580
  
  Pages: 1294-1302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.2006
- Author(s)
  Gotanda T, Haraguchi M, Tachiwada T, Shinkura R, Koriyama C, Akiba S, Kawahara M, Nishiyama K, Sumizawa T, Furukawa T, Mimata H, Nomura Y, Akiyama S, Nakagawa M.
- Journal Title
  
  Int. J. Mol. Med. 17(6)
  
  Pages: 1085-1091
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] A functional role of intracellular loops of human multidrug resistance protein 1.2006
- Author(s)
  Xiao-Qin Ren, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama:, (他3名7番目)
- Journal Title
  
  J. Biochem (Tokyo) 140
  
  Pages: 313-318
- NAID
  10018841960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] 2-Deoxy-D-ribose inhibits hypoxiainduced apoptosis by suppressing the phosphorylation of p38 MAPK. Biochem.2006
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama:, (他10名14番目)
- Journal Title
  
  Biophys. Res. Commun. 342
  
  Pages: 280-285
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] 2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9.2006
- Author(s)
  Nakajima Y, Haraguchi M., Furukawa T., Yamamoto M., Nakanishi H., Tatematsu M., Akiyama S.
- Journal Title
  
  Int. J. Cancer 119(7)
  
  Pages: 1710-1716
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] The small heat shock protein alpha B-crystal lin inhibits differentiation-induced caspase 3 activation and myogenic differentiation.2006
- Author(s)
  Ikeda R, Yoshida K, Ushiyama M, Yamaguchi T, Iwashita K, Fukagawa T, Shibayama Y, Oiso S, Takeda Y, Kariyazono H, Furukawa T, Nakamura K, Akiyama S, Inoue I, Yamada K.
- Journal Title
  
  Biol. Pharm. Bull. 29(9)
  
  Pages: 1815-1819
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] A Functional Role of Intracellular Loops of Human Multidrug Resistance Protein 12006
- Author(s)
  Ren XQ., Furukawa T., Yamamoto M., Aoki S., Kobayashi M., Nakagawa M., Akiyama S.
- Journal Title
  
  J Biochem (Tokyo) 140(3)
  
  Pages: 313-318
- NAID
  10018841960
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Protection against DNA damage-induced apoptosis by the angiogenic factor thymidine phosphorylase lase2006
- Author(s)
  Jeung HC, Che XF, Haraguchi M, Zhao HY, Furukawa T, Gotanda T, Zheng CL, Tsuneyoshi K, Sumizawa T, Roh JK, Akiyama S.
- Journal Title
  
  FEBS Letter 580(5)
  
  Pages: 1294-1302
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] 2-Deoxy-D-ribose inhibits hypoxia-induced apoptosis by suppressing the phosphorylation of p38 MAPK.2006
- Author(s)
  Ikeda R, Che XF, Ushiyama M, Yamaguchi T, Okumura H, Nakajima Y, Takeda Y, Shibayama Y, Furukawa T, Yamamoto M, Haraguchi M, Sumizawa T, Yamada K, Akiyama S.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 342(1)
  
  Pages: 280-285
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.2006
- Author(s)
  Tsuneyoshi K., Haraguchi M., Hongye Z., Gotanda T,.Tachiwada T., Sumizawa T., Furukawa T., Baba M., Akiyama S., Nakagawa M.
- Journal Title
  
  Cancer Lett. 244(2)
  
  Pages: 239-246
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Direct activation of the human major vault protein gene by DNA-damaging agents.2006
- Author(s)
  Shimamoto Y., Sumizawa T., Haraguchi M., Gotanda T., Jueng HC., Furukawa T., Sakata R., Akiyama S.
- Journal Title
  
  Oncol. Rep. 15(3)
  
  Pages: 645-652
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] 2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylaseoverexpressing tumors by suppressing matrix metalloprotease-9.2006
- Author(s)
  Yuichi Nakajima, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama., (他3名7番目)
- Journal Title
  
  Int. J. Cacncer 119
  
  Pages: 1710-1716
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Overexpression of survivin in primary ATL cells and sodium arsenite induces apoptosis by down-regulating survivin expression in ATL cell lines.2006
- Author(s)
  Xiao-Fang Che, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama., (他8名12番目)
- Journal Title
  
  Blood 15
  
  Pages: 4880-4887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Molecular basis for the involvement of thymidine phosphorylase in cancer invasion.2006
- Author(s)
  Takenari Gotanda, Tatsuhiko Furukawa, Shin-ichi Akiyama, Masayuki Nakagawa., (他10名13番目)
- Journal Title
  
  Int. J. Mol. Med. 17
  
  Pages: 1085-1091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Multidrug resistance-associated protein MRP-1 regulates dauei diapause by its export activity in Caenorhabditis elegans.2005
- Author(s)
  Yabe T., Suzuki N., Furukawa T., Ishihara T., Katsura I.
- Journal Title
  
  Development 132(14)
  
  Pages: 3197-3207
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] GSH suppresses a tryptic site in the C-terminal half of human MRP1.2005
- Author(s)
  Xiao-Qin Ren, Tatsuhiko Furukawa, Shin-ichi Akiyama., (他7名10番目)
- Journal Title
  
  J. Biol. Chem. 280
  
  Pages: 6231-6237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] MRP1 mutated in the L0 region transports SN-38 but not leukotriene C4 or estradiol-17 (β-D-glucuronate).2005
- Author(s)
  Tomohiro Noguchi, Shin-ichi Akiyama, Tatsuhiko Furukawa., (他14名16番目)
- Journal Title
  
  Biochem. Pharmacol. 70
  
  Pages: 1056-1065
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Cepharanthine potently enhances the sensitivity of anticancer Agents in K562 cells2005
- Author(s)
  Ikeda, R., Che, X-F, Yamaguchi, T., Ushiyama, M., Zeng, C-L., Okumura, H., Takeda, Y, Shibayama, Y, Nakamura, K., Jeung, H-C., Furukawa, T., Sumizawa, T., Haraguchi, M., Akiyama.S., Yamada K.
- Journal Title
  
  Cancer Sci 96
  
  Pages: 327-376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] MRP1 mutated in the L_0 region transports SN-38 but not leukotriene C_4 or estradiol-17 (beta-D-glucuronate).2005
- Author(s)
  Noguchi T., Ren XQ., Aoki S., Igarashi Y., Che XF.Nakajima Y, Takahashi H., Mitsuo R., Tsujikawa K., Sumizawa T., Haraguchi M., Kobayashi M., Goto S., Kanehisa M., Aikou T., Akiyama S., Furukawa T.
- Journal Title
  
  Biochem Pharmacol 70 (7)
  
  Pages: 1056-1065
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Cepharanthine potently enhances the sensitivity of anticancer agents in K562 cells.2005
- Author(s)
  Ryuji Ikeda, Tatsuhiko Furukawa, Shin-ichi Akiyama, Katsushi Yamada:, (他11名14番目)
- Journal Title
  
  Cancer Sci. 96
  
  Pages: 327-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Cepharanthine potently enhances the sensitivity of anticancer agents in K562 cells.2005
- Author(s)
  Ikeda R., Che XF., Yamaguchi T., Ushiyama M., Zheng CL., Okumura H., Takeda Y., Shibayama Y., Nakamura K., Jeung HC., Furukawa T., Sumizawa T., Haraguchi M., Akiyama S., Yamada K.
- Journal Title
  
  Cancer Sci. 96(6)
  
  Pages: 372-376
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] GSH suppresses a tryptic site in the C-terminal half of human MRP1.2005
- Author(s)
  Ren, X-Q., Furukawa, T., Nakajima, Y, Takahasi, Aoki, H., Sumizawa, T., Haraguchi, M., Kobayashi, M., Chijiwa, K., Akiyama, S.
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 6231-6237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] Characterization of MVP and VPARP assembly into vault ribonucleoprotein complexes.2005
- Author(s)
  Zheng CL., Su nizawa T., Che XF., Tsuyama S., Furukawa T., Haraguchi M., Gao H., Gotanda T., Jueng HC., Murata F., Akiyama S.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 326(1)
  
  Pages: 100-107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Thymidine phosphorylase suppresses apoptosis induced by microtubuleinterfering agents.2005
- Author(s)
  Hei-Cheul Jueng, Tatsuhiko Furukawa, Shin-ichi Akiyama., (他6名9番目)
- Journal Title
  
  Biochem. Pharmacol. 70
  
  Pages: 13-21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Thymidine phosphorylase suppresses apoptosis induced by microtubule-interfering agents.2005
- Author(s)
  Jeung HC., Che XF., Haraguchi M., Furukawa T., Zheng CL., Sumizawa T., Rha SY., Roh JK., Akiyama SI.
- Journal Title
  
  Biochem Pharmacol. 70(1)
  
  Pages: 13-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Development cuff a novel screening system for phytoecdysteroids in the environmental pollutants using mammalian cell line.2005
- Author(s)
  Komatsu M., Ando S., Takumi S., Furukawa T., Komatsu Y., Aoyama K., Takeuchi T.
- Journal Title
  
  Current Topics in Pharmacology 9(1)
  
  Pages: 81-89
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] GSH inhibits trypsinization of the C-terminal half of human MRP1.2005
- Author(s)
  Ren X-Q., Furukawa T., Nakajima Y., Takahashi H., Aoki S., Sumizawa, T., Haraguchi M., Kobayashi M., Chijiwa K., Akiyama S.
- Journal Title
  
  J. Biol. Chem. 280(7)
  
  Pages: 6231-6237
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590272
[Journal Article] Function of the ABC signature sequences in the human multidrug resistance protein 1.2004
- Author(s)
  Ren, X.-Q., Furukawa, T., Haraguchi, M., Sumizawa, T., Aoki, S., Kobayashi, M., Akiyama, S.
- Journal Title
  
  Mol.Pharmacol. 65
  
  Pages: 1536-1542
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] Characterization of MVP and VPARP assembly into vault ribonucleoprotein complexes.2004
- Author(s)
  Zheng, C-L., Sumizawa, T., Che, X-F, Tsuyama, S., Furukawa, T., Haraguchi, M., Gao, H., Gotanda, T., Jueng, H-Cl., Murata, F., Akiyama, S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 326
  
  Pages: 100-107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] Inhibition of Metastasis of tumor cells overexpressing theymidine phosphorylase by 2-Deoxy-L-ribose.2004
- Author(s)
  Nakajima, Y., Gotanda, T., Uchimiya, H., Furukawa, T., Haraguchi, M., Ikeda, R., Sumizawa, T., Yoshida, H., Akiyama, S.
- Journal Title
  
  Cancer Res. 64
  
  Pages: 1749-1801
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] Breast cancer resistance protein (BCRP/ABCG2) induces cellular resistance to HIV-1 nucleoside reverse transcriptase inhibitors.2003
- Author(s)
  Wang, X., Furukawa, T., Nitanda, T., Okamoto, M., Sugimoto, Y., Akiyama, S., Baba, M.
- Journal Title
  
  Mol.Pharmacol. 63
  
  Pages: 65-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] Localization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP1.2003
- Author(s)
  Ren, X.-Q., Furukawa, T., Aoki, S., Sumizawa, T., Haraguchi, M., Che, X-F., Kobayashi, M., Akiyama, S.
- Journal Title
  
  Br.J.Pharmacol. 138
  
  Pages: 1553-1561
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] Thymidine phosphorylase inhibits apoptosis induced by cisplatin.2003
- Author(s)
  Ikeda, R., Furukawa, T., Mitsuo, R., Noguchi, T., Kitazono, M., Okumura, H., Sumizawa, T., Haraguchi, M., Che, X-F, Uchimiya, H., Nakajima, Y., Ren, X-Q., Oiso, S., Inoue, I., Yamada, K., Akiyama, S.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 301
  
  Pages: 358-363
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Journal Article] The role of thymidine phosphorylase in the induction of early growth response protein-1 and thrombospondin-1 by 5-flurouracil in human carcinoma cells.
- Author(s)
  Shigeto Matushita, Tatsuhiko Furukawa, Masatatsu Yamamoto, Shin-ichi Akiyama., (他13名17番目)
- Journal Title
  
  Int. J. Oncol. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Major vault protein forms complexes with hypoxia-inducible factor (HIF)-1・and reducesHIF-1・・level in ACHN human renal adenocarcinoma cells.
- Author(s)
  Ken-ichi Iwashita, Tatsuhiko Furukawa, Shin-ichi Akiyama, Katsushi Yamada., (他4名7番目)
- Journal Title
  
  Cancer Sci. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016058
[Journal Article] Thymidine phosphorylase suppresses apoptosis induced by Microtubule-interfering agents.
- Author(s)
  Jeung, H-C., Che, X-F, Haraguchi, M., Furukawa, T., Zeng, C-L., Sumizawa, T., Rha, S-Y, Akiyama, S.
- Journal Title
  
  Biochemical Pharmacol. (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590277
[Patent] 抗がん剤の感受性及び癌の予後に対する診断マーカー2016
- Inventor(s)
  河原康一、古川龍彦、下川倫子、川畑拓斗、白石岳大、濱崎研悟
- Industrial Property Rights Holder
  河原康一、古川龍彦、下川倫子、川畑拓斗、白石岳大、濱崎研悟
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2016-172195
- Filing Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-16K07121
[Patent] 新規ベンズイミダゾール誘導体及びその用途2012
- Inventor(s)
  辻川和丈、田中明人、青木俊二、水野裕章、所美雪、古川龍彦
- Industrial Property Rights Holder
  大阪大学、兵庫医療大学、鹿児島大学
- Industrial Property Number
  2012-045267
- Filing Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-22501047
[Patent] 新規ベンズイミダゾール誘導体及びその用途2012
- Inventor(s)
  辻川和丈、田中明人、青木俊二、水野裕章、所美雪、古川龍彦
- Industrial Property Rights Holder
  兵庫医療大学、鹿児島大学、大阪大学
- Filing Date
  2012-03-01
- Data Source
  KAKENHI-PROJECT-22510236
[Patent] 水溶性ホルマザンを生成することができるテトラゾリウムを用いた定量的軟寒天コロニー形成アッセイ2011
- Inventor(s)
  古川龍彦
- Industrial Property Rights Holder
  鹿児島大学
- Industrial Property Number
  2011-219433
- Filing Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22501047
[Patent] 水溶性ホルマザンを生成することができるテトラゾリウムを用いた定量的軟寒天コロニー形成アッセイ2011
- Inventor(s)
  古川龍彦
- Industrial Property Rights Holder
  鹿児島大学
- Filing Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22510236
[Patent] 水溶性ホルマザンを生成することができるテトラゾリウムを用いた定量的軟寒天コロニー形成アッセイ2011
- Inventor(s)
  古川龍彦
- Industrial Property Rights Holder
  鹿児島大学
- Filing Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] BHLHE41は肺腺がんの予後良好な因子であり、オートファジー細胞死を誘導する2020
- Author(s)
  古川龍彦、南　謙太朗、山本雅達、河原康一
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K22566
[Presentation] BHLHE41による肺腺がん進行の抑制効果2020
- Author(s)
  古川龍彦、南　謙太朗、山本雅達、河原康一
- Organizer
  がん分子標的学会
- Data Source
  KAKENHI-PROJECT-19K22566
[Presentation] 遺伝子増幅を制御する分子による抗癌剤耐性の克服2019
- Author(s)
  南謙太朗、中岡博史、山本雅達、新里能成、河原康一、井ノ上逸朗、古川龍彦
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] BHLHE41/DEC2によって遺伝子増幅は減少する2019
- Author(s)
  南謙太朗、山本雅達、中岡博史、落合博、下川倫子、河原康一、井ノ上逸朗、古川龍彦
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] DEC2は肺腺癌においてオートファジー細胞死を誘導する2019
- Author(s)
  南謙太朗, 山本雅達, 新里能成, 河原康一, 佐藤雅美, 古川龍彦
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K22566
[Presentation] BHLHE41/DEC2によって遺伝子増幅は減少する2019
- Author(s)
  南謙太朗、山本雅達、中岡博史、落合博、下川倫子、河原康一、井ノ上逸朗、古川龍彦
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K22566
[Presentation] DEC2は肺腺癌においてオートファジー細胞死を誘導する2019
- Author(s)
  南謙太朗, 山本雅達, 新里能成, 河原康一, 佐藤雅美, 古川龍彦
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 遺伝子増幅を制御する分子による抗癌剤耐性の克服2019
- Author(s)
  南謙太朗、中岡博史、山本雅達、新里能成、河原康一、井ノ上逸朗、古川龍彦
- Organizer
  第11回トランスポーター研究会九州部会
- Data Source
  KAKENHI-PROJECT-19K22566
[Presentation] 増幅遺伝子コピー数を減少させる遺伝子の変化2018
- Author(s)
  南謙太朗、古川龍彦
- Organizer
  先進ゲノム解析研究推進プラットフォーム（先進ゲノム支援）班会議
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体再編成により細胞分裂を監視する新たなオルガネラストレス応答2018
- Author(s)
  河原康一、古川龍彦
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 腫瘍抑制因子BHLHE41のユビキチンプロテアゾーム経路による分解2018
- Author(s)
  南謙太郎、山本雅達、新里能成、河原康一、関原和正、佐藤雅美、古川龍彦,
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] Thymidine catabolism and cancer2018
- Author(s)
  古川龍彦, 田畑祥、山本雅達、南謙太郎、河原康一
- Organizer
  第77回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体を標的としたp53活性化機構による新たな癌治療薬2018
- Author(s)
  河原康一、古川龍彦
- Organizer
  第22回がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] TP発現による解糖系を介した低栄養適応性の賦与2018
- Author(s)
  古川龍彦, 田畑祥、山本雅達、南謙太郎
- Organizer
  第91回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体による細胞分裂制御と癌治療戦略2017
- Author(s)
  河原康一、川畑拓斗、下川倫子、古川龍彦
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] Mitotic regulation by nucleolar stress response2017
- Author(s)
  河原康一、川畑拓斗、古川龍彦
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] ATP7B is involved in doxorubicine relocalization from nuclei to late endosome and anticancer agent resistance2017
- Author(s)
  古川龍彦、新里能成、小松正治、南謙太朗、永田俊行、山本雅達、河原康一
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] A Novel Reporter System of Nucleolar Stress Response for Developing a New Class Cancer Therapy2017
- Author(s)
  Kohichi KAWAHARA, Takuto KAWAHATA, Michiko SHIMOKAWA, Takehiro SHIRAISHI, Taichi ASAHI, Tatsuhiko FURUKAWA
- Organizer
  17th International p53 Workshop
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 細胞分裂の異常を監視する核小体の新たな役割2017
- Author(s)
  川畑拓斗、河原康一、下川倫子、上條陽平、白石岳大、朝日汰一、山本雅達、新里能成、南謙太朗、武井孝行、吉田昌弘、有馬一成、濱田季之、古川龍彦
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体による細胞分裂監視2017
- Author(s)
  下川倫子、河原康一、川畑拓斗、上條陽平、新里能成、南謙太朗、有馬一成、濱田季之、古川龍彦
- Organizer
  第21回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体によりp53を制御するストレス応答を利用したがん治療薬の創生2017
- Author(s)
  下川倫子、河原康一、川畑拓斗、古川龍彦
- Organizer
  先端モデル動物支援プラットフォーム若手支援技術講習会
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] ATP7Bの発現はドキソルビシンの核から後期エンドゾームへの再局在と抗がん剤耐性に関与する2016
- Author(s)
  新里能成、南謙太朗、河原康一、古川龍彦
- Organizer
  第20回日本がん分子標的治療学会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体の再編成により細胞分裂を制御する新たなストレス応答と癌治療薬の開発2016
- Author(s)
  下川倫子, 河原康一, 川畑拓斗, 上條陽平, 白石岳大, 山本雅達, 新里能成, 南謙太朗, 有馬一成, 濱田季之, 古川龍彦
- Organizer
  第８９回生化学会大会
- Place of Presentation
  仙台国際センター東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] バイオイメージング技術による細胞分裂期チェックポイントとしての核小体ストレス応答の役割の解明2016
- Author(s)
  下川倫子、河原康一、川畑拓斗、上條陽平、新里能成、南謙太朗、有馬一成、濱田季之、古川龍彦
- Organizer
  第20回日本がん分子標的治療学会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] アクテオシドを用いたマイクロシスチンLRおよびファロイジンの細胞毒性の抑制2016
- Author(s)
  橋本海理、青木俊二、池田龍二、堀田夕貴、塩崎一弘、古川龍彦、内匠正太、小松正治
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] マイクロシスチンLRが誘導するアノイキス抵抗性細胞の低酸素応答2016
- Author(s)
  堀田夕貴、内匠正太、橋本海理、塩崎一弘、池田龍二、古川龍彦、小松正治
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体ストレス応答による細胞分裂監視機構と抗癌剤の開発2016
- Author(s)
  河原康一、川畑拓斗、下川倫子、上條陽平、新里能成、南謙太朗、有馬一成、濱田季之、古川龍彦
- Organizer
  第20回日本がん分子標的治療学会　学術集会
- Place of Presentation
  別府国際コンベンションセンター（大分県別府市）
- Year and Date
  2016-05-30
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] RNA epigeneticsによる生体制御の基盤研究2016
- Author(s)
  長谷拓朗、大塩郁幹、上田裕子、北恵郁緒里、西本愛、犬伏智子、古川龍彦、辻川和丈
- Organizer
  第３９回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] 核小体ストレス応答による細胞分裂監視機構とこれを利用した抗がん剤の開発2016
- Author(s)
  河原康一、川畑拓斗、下川倫子、上條陽平、白石岳大、山本雅達、新里能成、南謙太朗、有馬一成、濱田季之、古川龍彦
- Organizer
  日本ケミカルバイオロジー学会　第11回年会
- Place of Presentation
  京都テルサ（京都府京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] エネルギー代謝を制御する核小体ストレス応答の分裂期チェックポイント機構としての新たな役割の解明2016
- Author(s)
  川畑　拓斗、河原　康一、下川　倫子、山本　雅達、新里　能成、南　謙太朗、有馬　一成、濱田　季之、古川　龍彦
- Organizer
  第４回がんと代謝研究会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2016-07-07
- Data Source
  KAKENHI-PROJECT-16K07121
[Presentation] The attenuation of MLH1 expression confers to acquisition of temozolomide resistance of glioblastoma cells and recurrence of glioblastomas in the course administration of temozolomide2013
- Author(s)
  Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, Ikeda R, Yamamoto M, Hirano H, Arita K
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 高浸透圧によって誘導される Major vault protein(MVP) の発現亢進機序2013
- Author(s)
  田實裕介、池田龍二、西澤由紀彦、山口辰哉、山本雅達、田畑祥、秋山伸一、山田勝士、古川龍彦、武田泰生
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Expression of CNT1 and RRM1 are involved in gemcitabine resistant of pancreatic cancer cells2013
- Author(s)
  Minami K, Yamamoto M, Ikeda R, Komatsu M, Kawahara K, Shinsato Y, Tabata S, Yamada K, Akiyama S, Takeda Y, Furukawa T
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  19th International Charles Heidelberger Symposium on Cancer Research
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] The attenuation of MLH1 expression confers to acquisition of temozolomide resistance of glioblastoma cells and recurrence of glioblastomas in the course administration of temozolomide2013
- Author(s)
  Shinsato Y, Furukawa T, Yunoue S, Yonezawa H, Minami K, Nishizawa Y, Ikeda R, Yamamoto M, Hirano H, Arita K
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  Kagoshima
- Year and Date
  2013-02-16
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 高浸透圧で誘導されるヴォールトの発現亢進機序と高浸透圧耐性化機構2013
- Author(s)
  池田龍二、田實裕介、西澤由紀彦、古川龍彦、秋山伸一、山田勝士、武田泰生
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 5-AZa-2-deoxy cytidine (5-Aza-CdR) enhance the sensitivity of 5-fluorouracil (5-FU) in KB3-1 human carcinoma cells2013
- Author(s)
  Nishizawa Y, Ikeda R, Tabata S, Tajitsu Y, Kawahara K, Yamamoto M, Shinsato Y, Minami K, Akiyama S, Furukawa T, Takeda Y
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  Kagoshima
- Year and Date
  2013-02-13
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Expression of CNT1 and RRM1 are involved in gemcitabine resistant of pancreatic cancer cells2013
- Author(s)
  Minami K, Yamamoto M, Ikeda R, Komatsu M, Kawahara K, Shinsato Y, Tabata S, Yamada K, Akiyama S, Takeda Y, Furukawa T
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 高浸透圧によって誘導される Major vault protein(MVP)の発現亢進機序2013
- Author(s)
  田實裕介、池田龍二、西澤由紀彦、山口辰哉、山本雅達、田畑祥、秋山伸一、山田勝士、古川龍彦、武田泰生
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 高浸透圧で誘導されるヴォールトの発現亢進機序と高浸透圧耐性化機構2013
- Author(s)
  池田龍二、田實裕介、西澤由紀彦、古川龍彦、秋山伸一、山田勝士、武田泰生
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-23
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 5-AZa-2-deoxy cytidine (5-Aza-CdR) enhance the sensitivity of 5-fluorouracil (5-FU) in KB3-1 human carcinoma cells2013
- Author(s)
  Nishizawa Y, Ikeda R, Tabata S, Tajitsu Y, Kawahara K, Yamamoto M, Shinsato Y, Minami K, Akiyama S, Furukawa T, Takeda Y
- Organizer
  19th International Charles Heidelberger Symposium on Cancer Research
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 鼻咽頭リンパ腫のマクロファージと樹状細胞で特徴付けられる癌微小環境2012
- Author(s)
  蓮井和久、永井拓、古川龍彦、金蔵拓郎、河野嘉文、榮鶴義人、青笹克也、松山隆美
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] シンポジウム 2S13 生体遷移金属のパラダイムシフト:生体内シグナル分子としての機能 Abcb10は Heme 合成に必須であって、その欠損マウスはヒト Erythropoietic protoporyphyriaと類似の病態を示す2012
- Author(s)
  山本雅達、有村博、福重智子、河原康一、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ミトコンドリアABCトランスポーターのAbcb10の機能と病態2012
- Author(s)
  古川龍彦
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] MLH1発現低下とヒト glioma 細胞の TMZ 耐性獲得との関連2012
- Author(s)
  新里能成、南謙太朗、田畑祥、山本雅達、池田龍二、秋山伸一、古川龍彦
- Organizer
  第16回学術集会日本がん分子標的治療学会
- Place of Presentation
  北九州市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ゲフィチニブとエルロチブが H23 細胞のアポトーシスとc-MYC 発現に与える影響2012
- Author(s)
  末永光宏、古川龍彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ゲフィチニブとエルロチブが H23 細胞のアポトーシスと c-MYC発現に与える影響2012
- Author(s)
  末永光宏、古川龍彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ワークショップ1W7III-3 構造に基づいた ABC 蛋白質の分子メカニズムと疾患:ミトコンドリア ABC トランスポーターの Abcb10 の機能と病態2012
- Author(s)
  古川龍彦、山本雅達、福重智子、金蔵拓郎
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 5-aza-2-deoxycytidine(5-Aza)による5-flurouracil(5-FU)の抗腫瘍効果増強作用の機序解明2012
- Author(s)
  西澤由紀彦、池田龍二、田畑祥、田實裕介、牛山美奈、山本雅達、山田勝士、古川龍彦、武田泰生
- Organizer
  医療薬学フォーラム 2012 第20回クリニカルファーマシーシンポジウム
- Place of Presentation
  福岡
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] MLH1 発現低下とヒト glioma 細胞の TMZ 耐性獲得との関連2012
- Author(s)
  新里能成、南謙太朗、田畑祥、山本雅達、池田龍二、秋山伸一、古川龍彦
- Organizer
  第16回学術集会日本がん分子標的治療学会
- Place of Presentation
  北九州市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ヒト癌細胞の ROS産生および生存におけるチミジン異化作用の役割2012
- Author(s)
  田畑祥、池田龍二、山本雅達、古川龍彦、倉本卓哉、後東久嗣、植淵昌毅、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第16回学術集会日本がん分子標的治療学会
- Place of Presentation
  北九州市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Gemcitabine 耐性膵癌細胞での CNT1 と RRM1 の関わり2012
- Author(s)
  南謙太朗、山本雅達、河原康一、小松正治、池田龍二、田畑祥、秋山伸一、山田勝士、武田泰生、古川龍彦
- Organizer
  医療薬学フォーラム 2012 第20回クリニカルファーマシーシンポジウム
- Place of Presentation
  福岡
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Gemcitabine 耐性膵癌細胞での CNT1 と RRM1 の役割2012
- Author(s)
  南謙太朗、山本雅達、河原康一、小松正治、池田龍二、田畑祥、秋山伸一、山田勝士、武田泰生、古川龍彦
- Organizer
  第6回トランスポーター研究会九州部会
- Place of Presentation
  福岡
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] シンポジウム 2S13 生体遷移金属のパラダイムシフト:生体内シグナル分子としての機能 Abcb10 は Heme 合成に必須であって、その欠損マウスはヒト Erythropoietic protoporyphyria と類似の病態を示す2012
- Author(s)
  山本雅達、有村博、福重智子、河原康一、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1とRRM1の発現変化がGemcitabine耐性膵癌細胞株の耐性を担っている2012
- Author(s)
  南謙太郎、古川龍彦、山本雅達、池田龍二、小松正治、田畑祥、秋山伸一
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  北九州市
- Year and Date
  2012-06-24
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] 発がんプロモーターであるマイクロシスチン LR はアノイキス抵抗性を誘導する2012
- Author(s)
  高野博之、内匠正太、塩崎一弘、杉山靖正、古川龍彦、小松正治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Abcb10は Heme 合成に必須であって、その欠損マウスはヒト Erythropoietic protoporphyria と類似の病態を示す2012
- Author(s)
  山本雅達、有村博史、福重智子、河原康一、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第7回トランスポーター研究会年会
- Place of Presentation
  京都
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Abcb10 は Heme 合成に必須であって、その欠損マウスはヒト Erythropoietic protoporphyria と類似の病態を示す2012
- Author(s)
  山本雅達、有村博史、福重智子、河原康一、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第7回トランスポーター研究会年会
- Place of Presentation
  京都
- Year and Date
  2012-06-09
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ヒト癌細胞の生存におけるチミジン異化作用の役割2012
- Author(s)
  田畑祥、池田龍二、山本雅達、古川龍彦、倉本卓哉、後東久嗣、植淵昌毅、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ヒト癌細胞のROS 産生および生存におけるチミジン異化作用の役割2012
- Author(s)
  田畑祥、池田龍二、山本雅達、古川龍彦、倉本卓哉、後東久嗣、植淵昌毅、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第16回学術集会日本がん分子標的治療学会
- Place of Presentation
  北九州
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] DEC2 によるgemcitabine 耐性の抑制2012
- Author(s)
  古川龍彦、南謙太朗、西澤由紀彦、新里能成、山本雅達、河原康一、小松正治、田畑祥、秋山伸一、池田龍二
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] DEC2 による gemcitabine 耐性膵癌細胞の耐性抑制2012
- Author(s)
  南謙太朗、山本雅達、小松正治、池田龍二、新里能成、田畑祥、秋山伸一、古川龍彦
- Organizer
  第16回学術集会日本がん分子標的治療学会
- Place of Presentation
  北九州市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1 とRPM1 の発現変化が Gemcitabine 耐性膵臓癌細胞の耐性へ関与している2012
- Author(s)
  古川龍彦、南謙太朗、西澤由紀彦、池田龍二、山本雅達、武田泰生
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] DEC2 によるgemcitabine 耐性膵癌細胞の耐性抑制2012
- Author(s)
  南謙太朗、山本雅達、小松正治、池田龍二、新里能成、田畑祥、秋山伸一、古川龍彦
- Organizer
  第16回学術集会日本がん分子標的治療学会
- Place of Presentation
  北九州市
- Year and Date
  2012-06-28
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] DEC2によるgemcitabine耐性の抑制2012
- Author(s)
  古川龍彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ワークショップ 1W7III-3 構造に基づいた ABC 蛋白質の分子メカニズムと疾患:ミトコンドリア ABC トランスポーターの Abcb10の機能と病態2012
- Author(s)
  古川龍彦、山本雅達、福重智子、金蔵拓郎
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] DEC2 による gemcitabine 耐性の抑制2012
- Author(s)
  古川龍彦、南謙太朗、西澤由紀彦、新里能成、山本雅達、河原康一、小松正治、田畑祥、秋山伸一、池田龍二
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 発がんプロモーターであるマイクロシスチン LR はアノイキス抵抗性を誘導する2012
- Author(s)
  高野博之、内匠正太、塩崎一弘、杉山靖正、古川龍彦、小松正治
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-13
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ヒト癌細胞の生存におけるチミジン異化作用の役割2012
- Author(s)
  田畑祥、池田龍二、山本雅達、古川龍彦、倉本卓哉、後東久嗣、植淵昌毅、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 5-fluorouracil(5-FU)と5-aza-2-deoxycytidine(5-Aza)の組合せによる抗腫瘍効果増強の機序解明2012
- Author(s)
  西澤由紀彦、池田龍二、田畑祥、田實裕介、牛山美奈、山本雅達、山田勝士、古川龍彦、武田泰生
- Organizer
  第6回トランスポーター研究会九州部会
- Place of Presentation
  福岡
- Year and Date
  2012-09-01
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] CNT1 と RPM1の発現変化が Gemcitabine 耐性膵臓癌細胞の耐性へ関与している2012
- Author(s)
  古川龍彦、南謙太朗、西澤由紀彦、池田龍二、山本雅達、武田泰生
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-14
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 鼻咽頭リンパ腫のマクロファージと樹状細胞で特徴付けられる癌微小環境2012
- Author(s)
  蓮井和久、永井拓、古川龍彦、金蔵拓郎、河野嘉文、榮鶴義人、青笹克也、松山隆美
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] The difference between gefitinib and serum deprivation in cancer cells.2011
- Author(s)
  Suenaga M, Yamamoto M, Furukawa T
- Organizer
  American Association for Cancer Research 102nd Annual Meeting
- Place of Presentation
  Orange County Convention Center, Orlando, Florida.
- Year and Date
  2011-04-06
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ゼブラフィッシュ胚および OATP1B1 または OATP1B3 発現細胞を用いたマイクロシスチンの毒性評価2011
- Author(s)
  嶋佑介、塩崎一弘、杉山靖正、内匠正太、古川龍彦、小松正治
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Abcb10は Heme 合成に必須であって、その欠損マウスはヒト Erythropoietic protoporphyria と類似の病態を示す2011
- Author(s)
  山本雅達、有村博史、福重智子、河原康一、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 癌細胞での 5-FU 依存的early growth response protein-1 およびthrombospondin-1 発現亢進におけるthymidine phosphorylase の役割2011
- Author(s)
  西澤由紀彦、池田龍二、松下茂人、田畑祥、山本雅達、南謙太郎、山口辰哉、秋山伸一、古川龍彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Gemcitabine耐性膵癌細胞CNT1とRRM1の耐性機構への関与2011
- Author(s)
  南謙太郎、古川龍彦、山本雅達、西澤由紀彦、田畑祥、池田龍二、小松正治、秋山伸一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] The difference between gefitinib and serum deprivation in cancer cells2011
- Author(s)
  Suenaga M, Yamamoto M, Furukawa T
- Organizer
  American Association for Cancer Research 102nd Annual Meeting
- Place of Presentation
  Orange County Convention Center, Orlando, Florida
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 癌細胞における無血清培地とゲフィチニブによる影響の違い2011
- Author(s)
  末永光宏、古川龍彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1とRRM1の発現変化がGemcitabine耐性膵癌細胞株の耐性を担っている2011
- Author(s)
  南謙太郎、古川龍彦、山本雅達、池田龍二、小松正治、田畑祥、秋山伸一
- Organizer
  日本がん分子標的治療学会
- Place of Presentation
  福岡県北九州市
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] チミジンホスホリラーゼ発現腫瘍での5-flurouracil(5-FU)による thrombospondin-1(TSP-1) 発現誘導2011
- Author(s)
  西澤由紀彦、池田龍二、田畑祥、田實裕介、俣木博徳、古川龍彦、牛山美奈、山口辰哉、山本雅達、松下茂人、秋山伸一、山田勝士、武田泰生
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 前立腺癌で発現するPCA-1/ABH3は新たな治療標的分子である2011
- Author(s)
  古川龍彦
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎市
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1 と RRM1 の発現変化が Gemcitabine 耐性膵癌細胞 MGEM6 の耐性を担っている2011
- Author(s)
  南謙太朗、山本雅達、小松正治、池田龍二、田畑祥、秋山伸一、山田勝士、武田泰生、古川龍彦
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Gemcitabin e耐性でのSLC28, 29とRRM1の役割2011
- Author(s)
  山本雅達, 南謙太朗, 西澤由紀彦, 池田龍二, 小松正治, 古川龍彦
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎市
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] 前立腺癌で発現するPCA-1/ABH3は新たな治療標的分子である2011
- Author(s)
  古川龍彦
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎市
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] チミジンホスホリラーゼによってチミジンから派生した糖の解糖系への移行2011
- Author(s)
  田畑祥、山本雅達、池田龍二、古川龍彦、倉本卓哉、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第15回学術集会日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1と RRM1 の発現変化が Gemcitabine 耐性膵癌細胞株の耐性を担っている2011
- Author(s)
  南謙太朗、古川龍彦、山本雅達、池田龍二、小松正治、田畑祥、秋山伸一
- Organizer
  第15回学術集会日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Gemcitabine耐性でのSLC28,29とRRM1の役割2011
- Author(s)
  山本雅達, 南謙太朗, 西澤由紀彦, 池田龍二, 小松正治, 古川龍彦
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎市
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] 前立腺癌で発現する PCA-1/ABH3 は新たな治療標的分子である2011
- Author(s)
  古川龍彦、南謙太朗、西澤由紀彦、山本雅達、青木俊二、辻川和丈
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 癌細胞での 5-FU 依存的 early growth response protein-1 および thrombospondin-1 発現亢進におけるthymidine phosphorylase の役割2011
- Author(s)
  西澤由紀彦、池田龍二、松下茂人、田畑祥、山本雅達、南謙太郎、山口辰哉、秋山伸一、古川龍彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Gemcitabine耐性での SLC28,29 と RRM1 の役割2011
- Author(s)
  山本雅達、南謙太朗、西澤由紀彦、池田龍二、小松正治、古川龍彦
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] CNT1 と RRM1 の発現変化がGemcitabine 耐性膵癌細胞 MGEM6 の耐性を担っている2011
- Author(s)
  南謙太朗、山本雅達、小松正治、池田龍二、田畑祥、秋山伸一、山田勝士、武田泰生、古川龍彦
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] チミジンホスホリラーゼ発現腫瘍での5-flurouracil(5-FU)によるthrombospondin-1(TSP-1)発現誘導2011
- Author(s)
  西澤由紀彦、池田龍二、田畑祥、田實裕介、俣木博徳、古川龍彦、牛山美奈、山口辰哉、山本雅達、松下茂人、秋山伸一、山田勝士、武田泰生
- Organizer
  第64回日本薬理学会西南部会
- Place of Presentation
  福岡
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] MLH1 発現抑制とヒト gioma U251細胞の TMZ 耐性獲得の関連2011
- Author(s)
  新里能成、湯之上俊二、米澤大、南謙太朗、田畑祥、車暁芳、山本雅達、池田龍二、平野宏文、古川龍彦、秋山伸一、有田和徳
- Organizer
  第29回日本脳腫瘍学会
- Place of Presentation
  下呂温泉
- Year and Date
  2011-10-30
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Abcb10 は Heme 合成に必須であって、その欠損マウスはヒト Erythropoietic protoporphyria と類似の病態を示す2011
- Author(s)
  本雅達、有村博史、福重智子、河原康一、中川昌之、金蔵拓郎、古川龍彦
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Gemcitabine耐性膵癌細胞CNT1とRRM1の耐性機構への関与2011
- Author(s)
  南謙太郎、古川龍彦、山本雅達、西洋由紀彦、田畑祥、池田龍二、小松正治、秋山伸一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Gemcitabine 耐性膵臓癌細胞のCNT1 と RRM1 の耐性機構への関与2011
- Author(s)
  南謙太朗、古川龍彦、山本雅達、西澤由紀彦、田畑祥、池田龍二、小松正治、秋山伸一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] チミジンホスホリラーゼによってチミジンから派生した糖の解糖系への移行2011
- Author(s)
  田畑祥、山本雅達、池田龍二、古川龍彦、倉本卓哉、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第15回学術集会日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2011-06-23
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 癌細胞における無血清培地とゲフィチニブによる影響の違い2011
- Author(s)
  末永光宏、古川龍彦
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Gemcitabine 耐性膵臓癌細胞の CNT1と RRM1 の耐性機構への関与2011
- Author(s)
  南謙太朗、古川龍彦、山本雅達、西澤由紀彦、田畑祥、池田龍二、小松正治、秋山伸一
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-04
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ゼブラフィッシュ胚およびOATP1B1またはOATP1B3発現細胞を用いたマイクロシスチンの毒性評価2011
- Author(s)
  嶋佑介, 塩崎一弘, 杉山靖正, 内匠正太, 古川龍彦, 小松正治
- Organizer
  第5回トランスポーター研究会九州部会
- Place of Presentation
  宮崎市
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] CNT1と RRM1 の発現変化が Gemcitabine 耐性膵癌細胞株の耐性を担っている2011
- Author(s)
  南謙太朗、古川龍彦、山本雅達、池田龍二、小松正治、田畑祥、秋山伸一
- Organizer
  第15回学術集会日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1 and RRM1 are involve in the Gemcitabine resi stance mechanism in the pancreatic G emcitabine2010
- Author(s)
  T. Furukawa, K. Minami, M. Yamamoto, R. Ikeda, M. Komatsu
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] チミジンホスホリラーゼによる活性酵素の産生機構2010
- Author(s)
  田畑祥、山本雅達、池田龍二、古川龍彦、南謙太郎、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1 and RRM1 are in volve in the Gemcitabine resistance mechanism in the pancreatic Gemcitabine resistant cells2010
- Author(s)
  古川龍彦
- Organizer
  第33回日本分子生物学会年会第83回日本生化学大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] MLH1 発現抑制とヒトglioma U251 細胞の TMZ 耐性獲得との関連2010
- Author(s)
  新里能成、湯之上俊二、南謙太郎、田畑祥、車暁芳、山本雅達、池田龍二、古川龍彦、秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] CNT1 and RRM1 are involve in the Gemcitabine resistance mechanism in the pancreatic Gemcitabine2010
- Author(s)
  Tatsuhiko Furukawa, Kentaro Minami, Masatatsu Yamamoto, Ryuji Ikeda, Masaharu Komatsu
- Organizer
  第33回日本分子生物学会年会第83回日本生化会大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] 藍藻毒マイクロシスチンLRのカルボキシルエステラーゼ2による弱毒化2010
- Author(s)
  内匠正太, 安藤清一, 古川龍彦, 橋本満, 有薗幸司, 青山公治, 竹内亨, 小松正治
- Organizer
  日本水産学会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] ゲムシタビン耐性膵がん細胞での機構の解析2010
- Author(s)
  古川龍彦、南謙太郎、池田龍二、小松正治、山本雅達、田畑祥、秋山伸一
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] チミジンホスホリラーゼによる活性酵素の産生機構2010
- Author(s)
  田畑祥、山本雅達、池田龍二、古川龍彦、南謙太郎、倉本卓哉、大塚健司、武田泰生、山田勝士、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] CNT1 and RRM1 are involved in the Gemcitabine resistance mechanism in the pancreatic Gemcitabine resistant cells2010
- Author(s)
  Furukawa T, Minami K, Yamamoto M, Ikeda R, Komatsu M
- Organizer
  第33回日本分子生物学会年会第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Che X-F, Takeda Y, Akiyama S, Yamada K, The expression of CNT1 and RRM1 are related to the gemcitabine resistance in the pancreatic gemcitabine resistant cells2010
- Author(s)
  Minami K, Furukawa T, Komatsu M, Ikeda R, Yamamoto M, Tabata S, Shinsato Y
- Organizer
  The 20th Japan-Korea Joint Seminar on Pharmacology
- Place of Presentation
  Kagoshima
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 藍藻毒マイクロシスチンLRのカルボキシルエステラーゼ2による弱毒化2010
- Author(s)
  内匠正太、安藤清一、古川龍彦、橋本満、有薗幸司、青山公治、竹内亨、小松正治
- Organizer
  平成22年度日本水産学会春季大会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2010-03-27
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Gemcitabine 耐性膵癌細胞 MGEM6 の CNT1 と RRM1 の発現変化は耐性と関連している2010
- Author(s)
  南謙太郎、古川龍彦、山本雅達、池田龍二、小松正治、田畑祥、車暁芳、新里能成、秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ゲムシタビン耐性膵がん細胞での機構の解析2010
- Author(s)
  古川龍彦
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京都
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ゲムシタビン耐性膵がん細胞での機構の解析2010
- Author(s)
  古川龍彦, 南謙太郎, 池田龍二, 小松正治, 山本雅達, 田畑祥, 秋山伸一
- Organizer
  日本がん分子標的治療学会第14回学術集会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Gemcitabine耐性膵癌細胞MGEM6のCTN1とRRM1の発現変化は耐性と関連している2010
- Author(s)
  南謙太郎, 古川龍彦, 山本雅達, 池田龍二, 小松正治, 田畑祥, 車暁芳, 新里能成, 秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] The expression of CNT1 and RRM1 are related to the gemcitabine resistance in the pancreatic gemcitabine resistant cells2010
- Author(s)
  Minami K, Furukawa T, Komatsu M, Ikeda R, Yamamoto M, Tabata S, Shinsato Y, Che X-F, Takeda Y, Akiyama S, Yamada K
- Organizer
  The 20th Japan-Korea Joint Seminar on Pharmacology
- Place of Presentation
  Kagoshima
- Year and Date
  2010-11-17
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 銅輸送体ATP7A・核酸輸送体CNTの関与する抗癌剤耐性.2010
- Author(s)
  古川龍彦
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] ゲムシタビン耐性膵がん細胞での機構の解析2010
- Author(s)
  古川龍彦, 南謙太郎, 池田龍二, 小松正治, 山本雅達, 田畑祥, 秋山伸一
- Organizer
  日本がん分子標的治療学会第14回学術集会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Prostate cancer antigen-1 を分子標的とする前立腺癌治療創薬2010
- Author(s)
  辻川和丈、青木俊二、古川龍彦
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] A431 細胞と A549細胞におけるゲフィチニブの c-MYC への効果2010
- Author(s)
  末永光宏、古川龍彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ゲムシタビン耐性膵がん細胞での機構の解析2010
- Author(s)
  古川龍彦、南謙太郎、池田龍二、小松正治、山本雅達、田畑祥、秋山伸一
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Prostateancer antigen-1 を分子標的とする前立腺癌治療創薬2010
- Author(s)
  辻川和丈、青木俊二、古川龍彦
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] チミジンホスホリラーゼによる活性酵素の産生機構2010
- Author(s)
  田畑祥、山本雅達、池田龍二、古川龍彦、南謙太郎、倉本卓哉、大塚健司、武田泰生、山田勝士、西岡安彦、曽根三郎、秋山伸一
- Organizer
  チミジンホスホリラーゼによる活性酵素の産生機構
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 431 細胞と A549細胞におけるゲフィチニブの c-MYC への効果2010
- Author(s)
  末永光宏、古川龍彦
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] 藍藻毒マイクロシスチン-LRの発がんプロモーター活性の発現機序―12010
- Author(s)
  内匠正太, 古川龍彦, 安藤清一, 有薗幸司, 青山公治, 竹内亨, 小松正治
- Organizer
  日本水産学会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] 藍藻毒マイクロシスチン-LRの発がんプロモーター活性の発現機序―22010
- Author(s)
  小松正治, 内匠正太, 古川龍彦, 池田龍二, 住澤知之, 明永ひとみ, 前田雄太, 安藤清一, 青山公治, 竹内亨
- Organizer
  日本水産学会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] CNT1 and RRM1 are involved in the Gemcitabine resistance mechanism in the pancreatic Gemcitabine resistant cells2010
- Author(s)
  Furukawa T, Minami K, Yamamoto M, Ikeda R, Komatsu M
- Organizer
  第33回日本分子生物学会年会第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 藍藻毒マイクロシスチン-LRの発がんプロモーター活性の発現機序-12010
- Author(s)
  内匠正太、古川龍彦、安藤清一、有薗幸司、青山公治、竹内亨、小松正治
- Organizer
  平成22年度日本水産学会春季大会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Gemcitabine 耐性膵癌細胞MGEM6 の CNT1 と RRM1 の発現変化は耐性と関連している2010
- Author(s)
  南謙太郎、古川龍彦、山本雅達、池田龍二、小松正治、田畑祥、車暁芳、新里能成、秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] カルボキシルエステラーゼ2によるマイクロシスチンLRの解毒機構の解析2010
- Author(s)
  内匠正太、小松正治、古川龍彦、橋本満、有薗幸司、青山公治、竹内亨
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2010-10-23
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] 要匡マングース Tert 遺伝子断片を導入したマングース線維芽細胞の細胞生物学的機能解析2010
- Author(s)
  柳久美子、花房宏昭、森田この美、宝来佐和子、山本雅達、古川龍彦、渡邉泉、小倉剛
- Organizer
  第33回日本分子生物学会年会第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] CNT1 and RRM1 are in volve in the Gemcitabine resistance mechanism in the pancreatic Gemcitabine resistant cells2010
- Author(s)
  古川龍彦
- Organizer
  第33回日本分子生物学会年会第83回日本生化学大会合同大会
- Place of Presentation
  神戸市
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] MLH1 発現抑制とヒト glioma U251 細胞の TMZ 耐性獲得の関連2010
- Author(s)
  新里能成、湯之上俊二、米澤大、南謙太朗、田畑祥、山本雅達有田和徳、池田龍二、平野宏文、古川龍彦、秋山伸一
- Organizer
  第69回日本脳神経外科学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] Gemcitabine耐性膵癌細胞MGEM6のCTN1とRRM1の発現変化は耐性と関連している2010
- Author(s)
  南謙太郎, 古川龍彦, 山本雅達, 池田龍二, 小松正治, 田畑祥, 車暁芳, 新里能成, 秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪市
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] MLH1 発現抑制とヒトglioma U251 細胞の TMZ 耐性獲得との関連2010
- Author(s)
  新里能成、湯之上俊二、南謙太郎、田畑祥、車暁芳、山本雅達、池田龍二、古川龍彦、秋山伸一
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] マングース Tert 遺伝子断片を導入したマングース線維芽細胞の細胞生物学的機能解析2010
- Author(s)
  柳久美子、花房宏昭、森田この美、宝来佐和子、山本雅達、古川龍彦、渡邉泉、小倉剛、要匡
- Organizer
  第33回日本分子生物学会年会第83回日本生化学大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] 藍藻毒マイクロシスチン-LRの発がんプロモーター活性の発現機序-22010
- Author(s)
  小松正治、内匠正太、古川龍彦、池田龍二、住澤知之、明永ひとみ、前田雄太、安藤清一、青山公治、竹内亨
- Organizer
  平成22年度日本水産学会春季大会
- Place of Presentation
  神奈川県藤沢市
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] チミジンホスホリラーゼによる活性酵素の産生機構2010
- Author(s)
  田畑祥、山本雅達、池田龍二、古川龍彦、南謙太郎、西岡安彦、曽根三郎、秋山伸一
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] ゲノシタビン耐性膵がん細胞での機構の解析2010
- Author(s)
  古川龍彦
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2010-07-07
- Data Source
  KAKENHI-PROJECT-22501047
[Presentation] Gemcitabine 耐性細胞でのCNT1、 RRM1の発現変化2009
- Author(s)
  古川龍彦, 池田龍二, 小松正治, 秋山伸一
- Organizer
  日本癌学会学術総会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] カルボキシルエステラーゼ2 によるマイクロシスチンLRの細胞毒性抑制効果2009
- Author(s)
  内匠正太, 小松正治, 安藤清一, 古川龍彦, 橋本満, 有薗幸司, 青山公治, 竹内亨
- Organizer
  トランスポーター研究会第3回九州部会
- Place of Presentation
  鹿児島市
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] マイクロシスチンLRの肝臓選択毒性におけるOATP1B1またはOATP1B3並びにp53の貢献2009
- Author(s)
  小松正治、内匠正太、古川龍彦、安藤清一、青山公治、竹内亨
- Organizer
  トランスポーター研究会第3回九州部会(シンポジウム)
- Place of Presentation
  鹿児島市
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] マイクロシスチンLRの肝臓選択毒性におけるOATP1B1またはOATP1B3並びにp53の貢献2009
- Author(s)
  小松正治, 内匠正太, 古川龍彦, 安藤清一, 青山公治, 竹内亨
- Organizer
  トランスポーター研究会第3回九州部会(シンポジウム)
- Place of Presentation
  鹿児島市
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] カルボキシルエステラーゼ2によるマイクロシスチンLRの解毒機構の解析2009
- Author(s)
  内匠正太, 小松正治, 古川龍彦, 橋本満, 有薗幸司, 青山公治, 竹内亨
- Organizer
  日本生化学会大会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] カルボキシルエステラーゼ2によるマイクロシスチンLRの細胞毒性抑制効果2009
- Author(s)
  内匠正太、小松正治、安藤清一、古川龍彦、橋本満、有薗幸司、青山公治、竹内亨
- Organizer
  トランスポーター研究会第3回九州部会(シンポジウム)
- Place of Presentation
  鹿児島市
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Gemcitabine耐性細胞でのCNT1、RRM1の発現変化2009
- Author(s)
  古川龍彦、池田龍二、小松正治、秋山伸一
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  第68回日本癌学会学術総会
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] OATP1B3を介したオカダ酸の肝毒性の発現2009
- Author(s)
  前田雄太、小松正治、内匠正太、古川龍彦、安藤清一、青山公治、竹内亨
- Organizer
  トランスポーター研究会第3回九州部会(シンポジウム)
- Place of Presentation
  鹿児島市
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] OATP1B3を介したオカダ酸の肝毒性の発現2009
- Author(s)
  前田雄太, 小松正治, 内匠正太, 古川龍彦, 安藤清一, 青山公治, 竹内亨
- Organizer
  トランスポーター研究会第3回九州部会
- Place of Presentation
  鹿児島市
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21580250
[Presentation] Gemcitabinenの耐性と核酸輸送蛋白質2008
- Author(s)
  古川龍彦
- Organizer
  第31回日本分子生物学会年会第81回日本生化学大会合同大会
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2008-12-09
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] 膵癌細胞株MIAPaCa-2由来Gemcitabine耐性細胞の耐性機構の解析2008
- Author(s)
  古川龍彦
- Organizer
  第12回がん分子標的治療研究会総会
- Place of Presentation
  学術総合センター(東京都)
- Year and Date
  2008-06-27
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] 膵癌細胞株MIAPaCa-2由来Gemcitabine耐性細胞の耐性機構の解析2008
- Author(s)
  古川龍彦
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] A copper transporter ATP7A mediate multidrug resistance and the vesicle transport system.2007
- Author(s)
  Tatsuhiko Furukawa
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] 銅輸送体ATP7A発現による抗癌剤耐性の機構2007
- Author(s)
  古川龍彦
- Organizer
  第30回日本分子生物学学会年会・第80回日本生化学大会合同大会
- Place of Presentation
  パシフィコ横浜ヨコハマグランドインンターコンチネンタルホテル
- Year and Date
  2007-12-11
- Data Source
  KAKENHI-PROJECT-17016058
[Presentation] DEC2によるgemcitabine耐性の抑制
- Author(s)
  古川龍彦
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  北海道札幌市
- Data Source
  KAKENHI-PROJECT-22510236
[Presentation] ミトコンドリアABCトランスポーターのAbcb10の機能と病態
- Author(s)
  古川龍彦
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡県福岡市
- Data Source
  KAKENHI-PROJECT-22510236

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39. PASTAN Ira H

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FURUKAWA Tatsuhiko 古川 龍彦

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Mechanisms analysis of lung cancer suppression and cell death by an autophagy inducible gene BHLHE41.Principal Investigator

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Approach to regulatory mechanism of copy number variation the gene amplified.Principal Investigator

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Evaluation of moleclar bases for suppression of gene amplificationPrincipal Investigator

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Analysis of cooperative functions of transporters andvesicle transport system in efflux of anticancer agentsPrincipal Investigator

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Nano-scale analysis of the drug transport mechanism of MRP1Principal Investigator

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銅トランスポータATP7A・ATP7Bによる抗癌剤耐性の分子機構の解析Principal Investigator

FURUKAWA Tatsuhiko 古川龍彦