MORI Shuji 森秀治

Researcher Number	50220009
Other IDs
Affiliation (Current)	2025: 就実大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2007 – 2024: 就実大学, 薬学部, 教授 2009: 岡山大学, 医歯薬総合研究科, 准教授 2005 – 2006: 岡山大学, 医歯総合研究科, 助教授 2005: Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Associate Professor, 大学院・医歯薬学総合研究科, 助教授 2005: 岡山大学, 大学院医歯薬学総合研究科, 助教授 … More 2001 – 2004: 岡山大学, 大学院・医歯学総合研究科, 助教授 1999 – 2000: 岡山大学, 医学部, 助教授 1995 – 1996: 岡山大学, 医療技術短期大学部, 助手 1992 – 1993: 岡山大学, 医療技術短期大学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 47060:Clinical pharmacy-related / Applied pharmacology / Laboratory medicine / Circulatory organs internal medicine / 応用薬理学・医療系薬学 Except Principal Investigator Applied pharmacology / Basic Section 47060:Clinical pharmacy-related / General pharmacology / Psychiatric science / 内科学一般 / Laboratory medicine / Biological pharmacy / Science and Engineering
Keywords	Principal Investigator 炎症 / 組織リモデリング / サイトカイン / 分子標的 / 自然免疫 / 医療薬学 / plasma / 血漿 / 再生 / 分子標的薬 … More / 臨床薬理学 / 細胞融合 / DNase / 触媒抗体 / 鋳型分子 / イノムアッセイ / モレキュラーインプリンティング / アフィニティ沈降 / 温度感受性ポリマー / C反応性蛋白質 … More Except Principal Investigator chondroitin sulfate / cell culture / HMGB1 / 相互作用 / DAMPs / ダメージ関連分子パターン / AGEs / 終末糖化産物 / 敗血症 / Propionibacterium acnes / neuron / proteoglycan / 神経細胞死 / グルタミン酸 / ELISA / ヘパラン硫酸 / コンドロイチン硫酸 / プロテオグリカン / 細胞培養 / 蛋白質 / 炎症 / リボソームタンパク質 / LPS / サイトカイン / 慢性炎症 / トランスレーションリサーチ / ARDS / Immunothrombus / トランスレーショナルリサーチ / 薬理学 / HRG / macrophages / Kupffer cells / Lipopolysaccharide / IL-18 / knockout mice / hepatic injury / H2-receptors / histamine / アポトーシス / 細胞間シグナル伝達 / HDC / 肝炎治療 / プロステグランディン / 肝炎 / アドレナリン / プロスタグランディン / H2受容体 / ヒスタミン / 単球 / 接着分子 / インターロイキン18 / polymyxin / sepsis / cytokine / complex / plasma protein / interaction / adhesion molecule / leukocyte / 薬物標的 / プロテオミクス / 細胞接着分子 / 細胞間相互作用 / 白血球 / lymphocyte / sarcoidosis / プロピオニバクテリウムーアクネス / サイコイドーシス / サルコイド肉芽腫 / プロピオニバクテリウム-アクネス / サルコイドーシス / C- reactive protein / immunoassay / immuno PCR / イムノ PCR / C反応性タンパク質 / イムノアッセイ / イムノPCR / protective action / phoshpacan / delayd cell death / フォスファカン / 防止作用 / 遅発性神経細胞死 / protecfive action / phosphacan / proteoslycan / delayed cell death / heparan sulfate / cortical neuron / excitatory amino acids / cell death / グリタミン酸 / コンドロイチン硫酸プロテオグリカン / ミクロデキマトリン / 無血清培養 / 培養細胞 / 大脳皮質 / ラット / 培養神経細胞 / 大脳皮質神経細胞 / 興奮性アミノ酸 / 細胞死 / 抗腫瘍薬 / 抗体医薬 / 薬物治療学 / タンパク質 / シグナル伝達 / 構造生物学 / 関節リウマチ / 構造解析 / CCN / ウエスタンブロット / ヌクレオサイトカイン / 敗血漿 / マイクロファブリケーション / 合成ペプチド / ナノバイオデバイス / マイクロチップ電気泳動 / 細胞機能の模倣 / プロテインA / 抗体 / フォールディング / 高次構造 / 再構成 / 細胞機能模倣 / コートペプチド / 試験管内タンパク質合成 / リポソーム / 膜タンパク質 Less

炎症性疾患の新規治療標的としてのDAMPsインタラクトームの解明
- Principal Investigator
  
  渡邊政博
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
内因性ＡＧＥをコアとする組織リモデリング病態の増悪化機序解明と根治的治療法の開発Principal Investigator
- Principal Investigator
  
  森秀治
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Elucidation of the mechanism of tissue remodeling exacerbated by endogenous AGEs and the development of novel targeted therapyPrincipal Investigator
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Identification of inflammation suppressive DAMPs and their pathophysiological significance in inflammatory diseases
- Principal Investigator
  
  WATANABE Masahiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Study of the pathophysiological significance of endogenous AGE as an exacerbating factor for tissue remodeling, and the development of novel targeted therapyPrincipal Investigator
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Shujitsu University
Roles of AGEs as exacerbation factor in pathogenesis of tissue remodeling and the development of novel targeted therapyPrincipal Investigator
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University
Mechanism for microthrombus formation on NETosis and development of therapy for ARDS.
- Principal Investigator
  
  Nishibori Masahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Okayama University
Elucidating the molecular bases and pathophysiological significances of the extracellular inflammasome which drives chronic inflammation
- Principal Investigator
  
  Watanabe Masahiro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University
Pathophysiological role of AGEs as exacerbation factor in tissue remodeling and molecular targeted therapyPrincipal Investigator
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University
The development of broad-spectrum antitumor agents with anti-HMGB1 antibody and clarification of its action mechanism
- Principal Investigator
  
  WAKE HIDENORI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Pathogenesis of tissue remodeling caused by endogenous AGE and advanced targeting therapyPrincipal Investigator
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Shujitsu University
Structure-activity relationship of intercecullar signaling factor CCN family proteins and their application to drug deve lopment
- Principal Investigator
  
  MORI Hiroki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Shujitsu University
Characterization of cell-free protein synthesis system and theapplication for the synthesis of cell membrane protein
- Principal Investigator
  
  KATAOKA Masaroshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  The University of Tokushima
サイトカイン活性を有する核転写因子、ヌクレオサイトカインの情報伝達と敗血症病態
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  Okayama University
Study on regulation of tissue remodeling by histidine rich plasma factorsPrincipal Investigator
- Principal Investigator
  
  MORI Shuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Okayama University
Proteomics analysis of plasma protein complex regulating leukocyte interaction.
- Principal Investigator
  
  NISHIBORI Masahiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  OKAYAMA UNIVERSITY
Inducible histamine protects mice from P.acnes-primed and LPS-induced hepatitis through H2-receptor stimulation
- Principal Investigator
  
  TAKAHASHI Hideo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  OKAYAMA UNIVERSITY
Localigation oi P.acnes in sarcoid granumoma and identification of a liability antigen in P.acnes cell-wall component
- Principal Investigator
  
  NAKATA Yasunari
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  OKAYAMA UNIVERSITY
DNA分解能力を有する触媒抗体の開発と応用Principal Investigator
- Principal Investigator
  
  森秀治
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
分子識別能力を持つ抗体類似高分子の開発とイムノアッセイ系への応用Principal Investigator
- Principal Investigator
  
  森秀治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
A study on proteoglycans which have a protective action against neuronal death
- Principal Investigator
  
  IKAMOTO Motoi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  Okayama University
Development of immuno PCR method and its biomedical application
- Principal Investigator
  
  ENDO Hiroshi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Okayama University
温度感受性ポリマーを利用した生体内微量物質精製法の開発応用に関する研究Principal Investigator
- Principal Investigator
  
  森秀治
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Okayama University
A study on the cell death of primary cultured rat's cortical neurons induced by exicitatory amino acids and protective strategies against it.
- Principal Investigator
  
  OKAMOTO Motoi
- Project Period (FY)
  1992 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Psychiatric science
- Research Institution
  OKAYAMA UNIVERSITY

[Journal Article] Glycolaldehyde-derived advanced glycation end products promote macrophage proliferation via the JAK-STAT signaling pathway2023
- Author(s)
  Toyomura Takao、Watanabe Masahiro、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 7 Pages: 5849-5858
- DOI
  10.1007/s11033-023-08509-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K10465, KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701
[Journal Article] Cationic ribosomal proteins can inhibit pro‐inflammatory action stimulated by LPS+HMGB1 and are hindered by advanced glycation end products2023
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Biotechnology and Applied Biochemistry
  
  Volume: 71 Issue: 2 Pages: 264-271
- DOI
  10.1002/bab.2538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06657, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Identification of ribosomal protein L9 as a novel regulator of proinflammatory damage-associated molecular pattern molecules2022
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 4 Pages: 2831-2838
- DOI
  10.1007/s11033-021-07096-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Nordihydroguaiaretic acid inhibits glyoxalase I, and causes the accumulation of methylglyoxal followed by cell-growth inhibition2022
- Author(s)
  Watanabe Masahiro、Toyomura Takao、Ikegami Ryo、Suwaki Yui、Sada Minami、Wake Hidenori、Nishinaka Takashi、Hatipoglu Omer Faruk、Takahashi Hideo、Nishibori Masahiro、Mori Shuji
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 11 Pages: 10499-10507
- DOI
  10.1007/s11033-022-07929-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06588, KAKENHI-PROJECT-21K06701, KAKENHI-PROJECT-21K15354
[Journal Article] Interleukin-18 Amplifies Macrophage Polarization and Morphological Alteration, Leading to Excessive Angiogenesis.2018
- Author(s)
  Kobori T, Hamasaki S, Kitaura A, Yamazaki Y, Nishinaka T, Niwa A, Nakao S, Wake H, Mori S, Yoshino T, Nishibori M, Takahashi H
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 9 Pages: 334-334
- DOI
  10.3389/fimmu.2018.00334
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01881, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H07272, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K18996, KAKENHI-PROJECT-18K15035
[Journal Article] Decrease in histidine-rich glycoprotein as a novel biomarker to predict sepsis amongsystemic inflammatory response syndrome.2018
- Author(s)
  Kuroda K, Wake H, Mori S, Hinotsu S, Nishibori M, Morimatsu H.
- Journal Title
  
  Critical Care Medicine
  
  Volume: 46 Issue: 4 Pages: 570-576
- DOI
  10.1097/ccm.0000000000002947
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04686
[Journal Article] Effects of Histidine-rich glycoprotein on erythrocyte aggregation and hemolysis: Implications for a role under septic conditions.2018
- Author(s)
  Zhong H, Wake H, Liu K, Gao Y, Teshigawara K, Sakaguchi M, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 136(3) Issue: 3 Pages: 97-106
- DOI
  10.1016/j.jphs.2017.11.003
- NAID
  130007902144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-17K15580
[Journal Article] Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response2017
- Author(s)
  Watanabe M, Toyomura T, Wake H, Liu K, Teshigawara K, Takahashi H, Nishibori M, Mori S
- Journal Title
  
  Molecular and Cellular Biochemistry
  
  Volume: 印刷中 Issue: 1-2 Pages: 153-162
- DOI
  10.1007/s11010-017-3045-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H06785, KAKENHI-PROJECT-15K08605, KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15K08253
[Journal Article] The specific localization of advanced glycation end-products (AGEs) in rat pancreatic islets.2017
- Author(s)
  Morioka Y, Teshigawara K, Tomono Y, Wang D, Izushi Y, Wake H, Liu K, Takahashi HK, Mori S, Nishibori M.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 134(4) Issue: 4 Pages: 218-224
- DOI
  10.1016/j.jphs.2017.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
[Journal Article] Phagocytosis of Advanced Glycation End Products (AGEs) in Macrophages Induces Cell Apoptosis.2017
- Author(s)
  Gao Y, Wake H, Morioka Y, Liu K, Teshigawara K, Shibuya M, Zhou J, Mori S, Takahashi H, Nishibori M.
- Journal Title
  
  Oxid Med Cell Longev.
  
  Volume: 2017:8419035 Issue: 1 Pages: 8419035-8419035
- DOI
  10.1155/2017/8419035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08232, KAKENHI-PROJECT-16K08909, KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-15K08605
[Journal Article] Histidine-rich glycoprotein prevents septic lethality through regulation of immunothrombosis and inflammation.2016
- Author(s)
  Wake H, Mori S, Liu K, Morioka Y, Teshigawara K, Sakaguchi M, Kuroda K, Gao Y, Takahashi H, Ohtsuka A, Yoshino T, Morimatsu H, Nishibori M.
- Journal Title
  
  EBioMedicine
  
  Volume: 9 Pages: 180-194
- DOI
  10.1016/j.ebiom.2016.06.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04686, KAKENHI-PROJECT-26290039, KAKENHI-PROJECT-15K14382, KAKENHI-PROJECT-15K08253, KAKENHI-PROJECT-16K08232
[Journal Article] Histamine inhibits high mobility group box 1-induced adhesion molecule expression on human monocytes2013
- Author(s)
  Takahashi H、Sadamori H、Teshigawara K、Niwa A、Liu K、Wake H、Mori S、Yoshino T、Nishibori M
- Journal Title
  
  Eur J Phamacol
  
  Volume: Vol.718、No.1-3 Issue: 1-3 Pages: 305-313
- DOI
  10.1016/j.ejphar.2013.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591864, KAKENHI-PROJECT-23790601, KAKENHI-PROJECT-24390061, KAKENHI-PROJECT-24590337, KAKENHI-PROJECT-24590672, KAKENHI-PROJECT-25460649, KAKENHI-PROJECT-25461947, KAKENHI-PROJECT-25670464
[Journal Article] High-mobility group box protein 1 neutralization reduces development of diet-induced atherosclerosis in apolipoprotein e-deficient mice2011
- Author(s)
  Kanellakis P, Agrotis A, Kyaw TS, Koulis C, Ahrens I, Mori S, Takahashi HK, Liu K, Peter K, Nishibori M, Bobik A
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31 Issue: 2 Pages: 313-319
- DOI
  10.1161/atvbaha.110.218669
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Anti-high mobility group box-1 monoclonal antibody protects the blood-brain barrier from ischemia-induced disruption in rats2011
- Author(s)
  Zhang J, Takahashi HK, Liu K, Wake H, Liu R, Maruo T, Date I, Yoshino T, Ohtsuka A, Mori S, Nishibori M
- Journal Title
  
  Stroke
  
  Volume: 42 Issue: 5 Pages: 1420-1428
- DOI
  10.1161/strokeaha.110.598334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604, KAKENHI-PROJECT-23390348
[Journal Article] Prostaglandin E_2 inhibits advanced glycation end product-induced adhesion molecule expression on monocytes, cytokine production, and lymphocyte proliferation during human mixed lymphocyte reaction2010
- Author(s)
  Takahashi HK, Zhang J, Mori S, Liu K, Wake H, Liu R, Sadamori H, Matsuda H, Yagi T, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 334 Issue: 3 Pages: 964-972
- DOI
  10.1124/jpet.110.169102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Effect of nicotine on advanced glycation end product-induced immune response in human monocytes2010
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 332 Issue: 3 Pages: 1013-1021
- DOI
  10.1124/jpet.109.160861
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Ciprofloxacin inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes2010
- Author(s)
  Mori S, Takahashi HK, Liu K, Wake H, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  Br J Pharmacol
  
  Volume: 161 Issue: 1 Pages: 229-240
- DOI
  10.1111/j.1476-5381.2010.00880.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Ciprofloxacin inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes2010
- Author(s)
  Mori S
- Journal Title
  
  Brit J Pharmacol
  
  Volume: 161 Pages: 229-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Advanced glycation end products subspecies-selectively induce adhesion molecule expression and cytokine production in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Mori S, Wake H, Liu K, Yoshino T, Ohashi K, Tanaka N, Shikata K, Makino H, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330 Issue: 1 Pages: 89-98
- DOI
  10.1124/jpet.109.150581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells2009
- Author(s)
  Takahashi HK, Liu K, Wake H, Mori S, Zhang J, Liu R, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 331 Issue: 2 Pages: 656-670
- DOI
  10.1124/jpet.109.157594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes2009
- Author(s)
  Wake H, Takahashi HK, Mori S, Liu K, Yoshino T, Nishibori M
- Journal Title
  
  J Pharmacol Exp Ther
  
  Volume: 330 Issue: 3 Pages: 826-833
- DOI
  10.1124/jpet.109.155960
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590604
[Journal Article] Signal Transduction of Inflammatory Synoviocytes in Rheumatoid Arthritis2008
- Author(s)
  Mori, H., Nakanishi, T.
- Journal Title
  
  YAKUGAKU ZASSHI 128
  
  Pages: 263-268
- NAID
  110006572180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Cold-induced changes in gene expression in brown adipose tissue: implications for the activation of thermogenesis2008
- Author(s)
  Watanabe M, Yamamoto T, Mori C, Okada N, Yamazaki N, Kajimoto K, Kataoka M, Shinohara Y.
- Journal Title
  
  Biol Pharm Bull 31(5)
  
  Pages: 775-84
- NAID
  110006663927
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17076011
[Journal Article] Isolation of a mRNA Preferentially Expressed in Synoviocytes from Rheumatoid Arthrits That is Identical with Lumican, which Encodes a Collagen Binding Extracellular Matrix Protein2008
- Author(s)
  Mori, H, Nishida, K, Ozaki, T, Inoue, H, Nakanishi, T
- Journal Title
  
  J. Hard Tissue Biol. 17
  
  Pages: 125-130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Signal Transduction of Inflammatory Synoviocytes in Rheumatoid Arthritis2008
- Author(s)
  Hiroki Mori, Tohru Nakanishi
- Journal Title
  
  Yakugaku zasshi 128
  
  Pages: 263-268
- NAID
  110006572180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Isolation of a mRNA Preferentially Expressed in Synoviocytes from Rheumatoid Arthritis that is Identical with Lumican, which Encodes a Collagen Binding Extracellular Matrix Protein2008
- Author(s)
  Hiroki Mori, Kei-ichiro Nishida, Toshifumi Ozaki, Hiroshi Inoue, Tohru Nakanishi
- Journal Title
  
  J. Hard Tissue Biol. 17
  
  Pages: 125-130
- NAID
  110007081297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Characterization and Gene Expression Profiling of Human Mesenchymal Stem Cells2007
- Author(s)
  Mori, H., et. al.
- Journal Title
  
  J.Hard Tissue Biol 16
  
  Pages: 36-41
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Characterization and Gene Expression Profiling of Human Mesenchymal Stem Cells2007
- Author(s)
  Hiroki Mori, Yoshitaro Itano, Naoya Kobayashi, Yoshikazu Kosaka, Noriaki Tanaka, Hitoshi Nagatsuka, Masahisa Inoues, Kojun Setsu, Tohru Nakanishi
- Journal Title
  
  J. Hard Tissue Biol. 16
  
  Pages: 36-41
- NAID
  110006250205
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Expression profiles of BDNF splice variants in cultured DRG neurons stimulated with NGF. Biochem2007
- Author(s)
  Yoshikazu Matsuoka, Masataka Yokoyama, Hiroyuki Kobayashi, Megumi Omori, Yoshitaro Itano, Kiyoshi Morita, Hiroki Mori, Tohru Nakanishi
- Journal Title
  
  Biophys. Res. Commun. 362
  
  Pages: 682-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590092
[Journal Article] Analysis of sensitization to carboxymethylcellulose : identification of high risk group using ELISA and histamine release experiment.2004
- Author(s)
  Mori S
- Journal Title
  
  Inflammation Research 53
  
  Pages: 164-169
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] Effect of prostaglandin E2 on intercellular adhesion molecule-1 and B7 expression in mixed lymphocyte reaction.2003
- Author(s)
  Morichika T
- Journal Title
  
  Transplantation 75(12)
  
  Pages: 2100-2105
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] Histamine inhibits lipopolysaccharide-Induced Tumor Necrosis Factor-α Production in an Intercellular Adhesion Molecule-1 and B7.1-Dependent Manner.2003
- Author(s)
  Morichika T
- Journal Title
  
  J Pharmacol Exp Ther 304
  
  Pages: 624-633
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] Histidine-rich glycoprotein plus zinc reverses growth inhibition of vascular smooth muscle cells by heparin.2003
- Author(s)
  Mori S
- Journal Title
  
  Cell Tissue Res 312
  
  Pages: 353-359
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] Effect of prostaglandin E2 on intercellular adhesion molecule-1 and B7 expression in mixed lymphocyte reaction.2003
- Author(s)
  Morichika T
- Journal Title
  
  Transplantation 75(12)
  
  Pages: 2100-2105
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590467
[Journal Article] High affinity binding of histidine rich glycoprotein to nickel-nitrilotriacetic acid : the application to microquantification.2003
- Author(s)
  Mori S
- Journal Title
  
  Life Sci 73
  
  Pages: 93-102
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Journal Article] Nafamostat mesilate is an extremely potent inhibitor of human tryptase.2003
- Author(s)
  Mori S
- Journal Title
  
  Journal of Pharmacological Sciences 92
  
  Pages: 420-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590228
[Patent] 赤血球保護剤2018
- Inventor(s)
  西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 赤血球保護剤2017
- Inventor(s)
  西堀正洋、和氣秀徳、衷輝、森秀治、阪口政清
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-028738
- Filing Date
  2017-02-20
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] THERAPEUTIC AGENT, METHOD OF TREATMENT AND METHOD FOR PREDICTING THE SEVERITY OF SYSTEMIC INFLAMMATORY RESPONSE SYNDROME(SIRS), DISEASES CAUSED OR ACCOMPANIED BY NEUTROPHIL ACTIVATION2016
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約、勅使川原匡　他3名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016
- Acquisition Date
  2018
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 好中球活性化に起因する疾患の治療薬、治療方法及び検査方法2016
- Inventor(s)
  西堀　正洋、黒田　浩佐、森松　博史、森　秀治ほか５名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2016-01-14
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] サイトカインストーム抑制剤2015
- Inventor(s)
  西堀　正洋、森　秀治、和氣　秀徳
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-154972
- Filing Date
  2015-08-05
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] 好中球活性化に起因する疾患の治療薬及び検査方法2015
- Inventor(s)
  西堀正洋、森秀治、和氣秀徳、髙橋英夫、劉克約　ほか2名
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015
- Acquisition Date
  2017
- Data Source
  KAKENHI-PROJECT-15H04686
[Patent] サイトカインストーム抑制剤2015
- Inventor(s)
  西堀　正洋、森　秀治、和氣　秀徳
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-12-21
- Overseas
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] HMGB1-LPS共刺激誘導性炎症に対する生体内抑制因子の同定2023
- Author(s)
  森　秀治　他
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K06657
[Presentation] HMGB1+LPS共刺激誘導性炎症応答を制御する生体内因子の性状解析2022
- Author(s)
  森　秀治　他
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06657
[Presentation] HMGB1－LPS誘導性炎症応答を制御する生体内因子の探索研究2022
- Author(s)
  森　秀治　他
- Organizer
  第43回日本炎症再生医学会
- Data Source
  KAKENHI-PROJECT-21K06657
[Presentation] 抑制性DAMPsとしてのリボソーム構成分子RPL9の同定2022
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，西中崇，ハティポールオメルファルク，高橋英夫，西堀正洋，森　秀治
- Organizer
  第141回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06701
[Presentation] 新規AGEs結合分子AGE-BP2がDAMPsの作用に与える影響の解析2021
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，西中崇，逢坂大樹，王登莉，高橋英夫，西堀正洋，森秀治
- Organizer
  第139回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-21K06701
[Presentation] 終末糖化産物によるLPS－HMGB1共刺激炎症応答の相乗的活性化作用2021
- Author(s)
  森　秀治　他
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06657
[Presentation] LPS－HMGB1誘導性炎症応答の終末糖化産物による相乗的亢進作用2021
- Author(s)
  森　秀治　他
- Organizer
  第42回日本炎症再生医学会
- Data Source
  KAKENHI-PROJECT-21K06657
[Presentation] AGEs結合因子の探索と結合遮断ペプチドの同定2020
- Author(s)
  森　秀治　他
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] AGEs結合因子の単離とAGEs-RAGE結合抑制領域の同定2020
- Author(s)
  森　秀治　他
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] AGEs結合因子としてのLfの同定とマクロファージTNF-α発現応答変化2019
- Author(s)
  森秀治　他
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] AGEs結合因子の分子同定と炎症性サイトカイン発現応答への影響2019
- Author(s)
  森秀治　他
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] TWEAK誘導性内皮細胞応答と終末糖化産物による抑制2018
- Author(s)
  森　秀治他
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] Protective Effects of Histidine-rich Glycoprotein on Barrier Dysfunction of Vascular Endothelial Cells.2018
- Author(s)
  Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Pathophysiological role of a factor affecting AGEs-RAGE interaction on endothelial cell responses2018
- Author(s)
  Mori S et al
- Organizer
  第18回国際薬理学・臨床薬理学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06807
[Presentation] The role of histidine-rich glycoprotein on immunothrombosis in septic organ failure.2018
- Author(s)
  Wake H, Mori S, Teshigawara K, Liu K, Wang D, Gao Y, Takahashi HK, Nishibori M.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology (WCP2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Protective effects of histidine-rich glycoprotein (HRG) on human vascular endothelial cells2017
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Histidine-rich glycoprotein (HRG)の好中球制御による敗血症治療薬の可能性2017
- Author(s)
  和氣秀徳、高遠、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第132回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] The role of histidine-rich glycoprotein on NETosis and immunothrombosis in septic condition2017
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] AGEs-RAGE間相互作用に影響を与える生理活性因子の同定と性状2017
- Author(s)
  森　秀治　他
- Organizer
  ConBio2017（第90回日本分子生物学会，第90回日本生化学会合同大会）
- Data Source
  KAKENHI-PROJECT-15K08605
[Presentation] Protective effects of histidine-rich glycoprotein on barrier function of vascular endothelial cells.2017
- Author(s)
  Gao S, Gao Y, Wake H, Liu K, Teshigawara K, Mori S, Nishibori M.
- Organizer
  第131回日本薬理学会近畿部会
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Histidine-rich glycoprotein protects vascular endothelial cells and red blood cells in sepsis.2017
- Author(s)
  Wake H, Gao Y, Hui Z, Gao S, Mori S, Morimatsu H, Nishibori M.
- Organizer
  Sepsis2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Hitidine-Rich Glycoprotein as a Novel Prognostic Blomarker for Sepsis: Multicenter prospective observational study.2017
- Author(s)
  Kuroda K, Morimatsu H, Kawanoue N, Wake H, Mori S, Nishibori M.
- Organizer
  Sepsis2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] AGEsとTNF関連サイトカインとの相互作用部位の解析2016
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第26回創薬・薬理フォーラム
- Place of Presentation
  岡山大学医学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] AGEs 共存による Damps 関連サイトカイン類の機能変化2016
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] ヒト血管内皮細胞におけるHistidine rich glycoprotein (HRG) の保護効果2016
- Author(s)
  高　遠、和氣　秀徳、劉　克約、勅使川原　匡、森　秀治、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Endotoxemia併発急性膵炎に対するHistidine-rich gloycoprotein(HRG)の動態及び治療効果2016
- Author(s)
  寺尾欣也、和氣秀徳、森岡祐太、勅使川原匡、劉克約、高橋英夫、森秀治、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Damps関連サイトカインの機能に対するAGEsの影響2016
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター／東北大学川内北キャンパス（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] Histidine rich glycoproteinの敗血症時好中球性微小循環障害に対する影響2016
- Author(s)
  和氣秀徳、森秀治、劉克約、勅使川原匡、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] AGEs親和性因子としての60S ribosomal proteinの単離2016
- Author(s)
  森　秀治　他
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-15K08605
[Presentation] 敗血症時好中球微小循環イメージング2016
- Author(s)
  和氣　秀徳、森　秀治、高橋　英夫、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Protective effects of histidine rich glycoprotein (HRG) on human vascular endothelial cells2016
- Author(s)
  高遠、和氣秀徳、劉克約、勅使川原匡、森秀治、西堀正洋
- Organizer
  第129回日本薬理学会近畿部会
- Place of Presentation
  広島県医師会館（広島県広島市）
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症性ARDSにおけるimmunothrombus形成に対する高ヒスチジン糖タンパク質の役割2016
- Author(s)
  和氣秀徳、森秀治、高橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] AGEs-RAGE結合増大活性を示すHMGB1結合因子の探索2015
- Author(s)
  森　秀治
- Organizer
  第38回日本分子生物学会・第88回日本生化学会合同大会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K08605
[Presentation] 高ヒスチジン糖タンパク質（HRG）の敗血症性immunothrombosis形成に対する影響2015
- Author(s)
  和氣　秀徳、森　秀治、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第128回日本薬理学会近畿部会
- Place of Presentation
  千里ライフサイエンスセンター（大阪府豊中市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症病態における微小循環障害に対する高ヒスチジン糖タンパク質の役割2015
- Author(s)
  和氣　秀徳、森　秀治、高橋　英夫、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第38回日本分子生物学会年会　第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] Tissue factor ( TF ) 誘発DICモデルにおけるHistidine-rich glycoprotein ( HRG ) の動態及び治療効果について2015
- Author(s)
  寺尾　欣也、和氣　秀徳、森岡　祐太、勅使川原　匡、劉　克約、高橋　英夫、森　秀治、西堀　正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] 敗血症病態における高ヒスチジン糖タンパク質（HRG）の好中球形態と微小循環に対する影響2015
- Author(s)
  和氣　秀徳、森　秀治、劉　克約、勅使川原　匡、西堀　正洋
- Organizer
  第127回日本薬理学会近畿部会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] HMGB1と相互作用するサイトカインに対するAGEsの影響2015
- Author(s)
  渡邊政博，豊村隆男，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，森秀治
- Organizer
  BMB2015 第38回日本分子生物学会，第88回日本生化学会合同大会
- Place of Presentation
  神戸ポートアイランド（神戸ポートピアホテル，神戸国際会議場，神戸国際展示場，神戸商工会議所）（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15H06785
[Presentation] Histidine-Rich Glycoprotein as a Novel Prognostic Biomarker in Critically Ill Patients.2015
- Author(s)
  Kuroda K, Morimatsu H, Wake H, Mori S, Nishibori M.
- Organizer
  Euroanaesthesia 2015 (Annual meeting of European Society of Anesthesiology)
- Place of Presentation
  Berlin（Germany）
- Year and Date
  2015-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] SIRSにおける新たな重症度バイオマーカーとしてのHistidine-Rich Glycoprotein：前向き観察研究2015
- Author(s)
  黒田　浩佐、森松　博史、和氣　秀徳、森　秀治、西堀　正洋
- Organizer
  日本麻酔科学会第62回学術集会
- Place of Presentation
  神戸ポートピアホテル（兵庫県神戸市）
- Year and Date
  2015-05-28
- Data Source
  KAKENHI-PROJECT-15H04686
[Presentation] AGEs結合親和性に基づいたAGEs遮断ペプチドの同定2014
- Author(s)
  横山隆太，豊村隆男，和氣秀徳，勅使川原匡，劉克約，高橋英夫，西堀正洋，森　秀治
- Organizer
  第125回日本薬理学会近畿部会
- Place of Presentation
  岡山コンベンションセンター（岡山）
- Year and Date
  2014-06-20
- Data Source
  KAKENHI-PROJECT-24590672
[Presentation] コラゲナーゼ誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] HMGB1結合因子の網羅的アレイ探索と機能調節2014
- Author(s)
  森　秀治，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，豊村隆男
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-24590672
[Presentation] コラゲナーゼで誘発脳内出血モデルにおける抗HMGB1単クローン抗体の効果2014
- Author(s)
  劉克約、王登莉、和氣秀徳、勅使川原匡、髙橋英夫、森秀治、西堀正洋
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター(仙台)
- Year and Date
  2014-03-20
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] HMGB1結合因子によるAGEs-RAGE結合阻害解析2014
- Author(s)
  森　秀治，和氣秀徳，劉克約，勅使川原匡，高橋英夫，西堀正洋，豊村隆男
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-10-16
- Data Source
  KAKENHI-PROJECT-24590672
[Presentation] 高ヒスチジン糖タンパク質の好中球走化性に対する影響2013
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
- Organizer
  Merinoff World Congress 2013：HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitány,Sümeg, Hungary
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Protection of BBB disruption in ischemic and traumatic injuries by anti-HMGB1 monoclonal antibody2013
- Author(s)
  Nishibori M, Liu K, Okuma Y, Wake H, Teshigawara K, Takahashi H, Date I, Mori S
- Organizer
  Signalling in the Blood-Brain Barriers
- Place of Presentation
  Hotel Kapitany, Sumeg, Hungary
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Anti-HMGB1 Monoclonal Antibody Therapy for Traumatic Brain Injury in Rats2013
- Author(s)
  Nishibori M, Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Yamamoto Y, Yamamoto H, Ohtsuka A, Yoshino T, Otani N, Tomura S, Shima K, Takahashi H, Date I, Mori S
- Organizer
  Merinoff World Congress 2013 : HMGB1
- Place of Presentation
  Feinstein Institute for Medical Research, New York, USA
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] Anti-high mobility group box-1 antibody therapy for traumatic brain injury2012
- Author(s)
  Okuma Y, Liu K, Wake H, Maruo T, Teshigawara K, Tomura S, Otani N, Shima K, Yamamoto Y, Yamamoto H, Takahashi H, Mori S, Date I, Nishibori M
- Organizer
  Neuroscience 2012
- Place of Presentation
  New Orleans Morial Convention Center, New Orleans, USA
- Year and Date
  2012-10-16
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2012
- Author(s)
  和氣秀徳、森秀治、髙橋英夫、劉克約、勅使川原匡、西堀正洋
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] アレイ解析によるHMGB1相互作用因子の網羅的探索2012
- Author(s)
  森秀治
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-21590604
[Presentation] 頭部外傷モデルを用いた抗HMDB1抗体の神経保護効果の検討2012
- Author(s)
  大熊佑、劉克約、和氣秀徳、勅使川原匡、高橋英夫、森秀治、伊達勲、西堀正洋
- Organizer
  第121回日本薬理学会近畿部会
- Place of Presentation
  あわぎんホール(徳島)
- Year and Date
  2012-06-29
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 治療分子標的としてのHMGB1と創薬2012
- Author(s)
  森秀治
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-21590604
[Presentation] 高ヒスチジン糖タンパク質はHMGB1-ヘパリン複合体誘導血管新生を抑制する2011
- Author(s)
  和氣秀徳、森秀治、劉克約、高橋英夫、西堀正洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] HRGのHMGB1-ヘパリン複合体誘導性血管新生調節機構2011
- Author(s)
  和氣秀徳、森秀治、高橋英夫、西堀正洋
- Organizer
  第120回日本薬理学会近畿部会
- Place of Presentation
  ホテルグランヴィア京都(京都)
- Year and Date
  2011-11-11
- Data Source
  KAKENHI-PROJECT-23790601
[Presentation] 抗HMGB1抗体の結合特異性と機能解析2010
- Author(s)
  森秀治
- Organizer
  第49回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-21590604
[Presentation] 関節炎におけるテトラスパニンの機能解析2009
- Author(s)
  森宏樹, 松下有美, 岡田充泰, 中島利博, 中川周士, 新井裕志, 久保俊一, 中西徹
- Organizer
  日本薬学会第129年会
- Place of Presentation
  国立京都国際会館など(京都市)
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] Establi shment of over expression system of mult ifunctional CCN family proteins for structural analysis2008
- Author(s)
  Kato, J, Mori, H, Nakani shi, T
- Organizer
  The ASCB 48th Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco, CA, USA
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] Establishment of overexpression system of multifunctional CCN family proteins for structural analysis2008
- Author(s)
  Junko Kato, Hiroki Mori, and Tohru Nakanishi
- Organizer
  The ASCB 48th Annual Meeting
- Place of Presentation
  Moscone Center, San Francisco, CA, USA
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] DNAチップを用いた関節リウマチ原因遺伝子の解明2008
- Author(s)
  松下有美, 森宏樹, 西田圭一郎, 尾崎敏文, 長塚仁, 中西徹
- Organizer
  第47回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  岡山コンベンションセンター「ママカリフォーラム」(岡山市)
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] 炎症性疼痛においてBDNF遺伝子は後根神経節からプロモーター選択的に発現誘導される2008
- Author(s)
  松岡義和, 横山正尚, 小林宏行, 大森恵, 板野義太郎, 森田潔, 森宏樹, 中西徹
- Organizer
  日本薬学会第128年会
- Place of Presentation
  パシフィコ横浜など(横浜市)
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] アセチルコリン受容体ノックアウトマウスの遺伝子発現解析2008
- Author(s)
  岡田充泰, 森宏樹, Maskos Uw, Changeux Jean-Pierre, 筒井公子, 中西徹
- Organizer
  第47回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  岡山コンベンションセンター「ママカリフォーラム」(岡山市)
- Year and Date
  2008-11-08
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] DNAマイクロアレイによる関節リウマチ滑膜関連遺伝子の単離とWISP遺伝子を中心とするその解析2008
- Author(s)
  森宏樹, 西田圭一郎, 中西徹
- Organizer
  第17回硬組織再生生物学会
- Place of Presentation
  徳島文理大学(徳島市)
- Year and Date
  2008-08-30
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] ヒト間葉系幹細胞の遺伝子発現解析と分化制御機構の解明2007
- Author(s)
  永留舞, 森宏樹, 岡田充泰, 松下有美, 小阪芳和, 小林直哉, 田中紀章, 中西徹
- Organizer
  第46回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザ「かるぽーと」,四国医療工学専門学校(高知市)
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19590092
[Presentation] AGEs-RAGE相互作用に基づいた遮断物質探索系への応用
- Author(s)
  森　秀治
- Organizer
  第86回日本生化学会大会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-24590672
[Presentation] 70kD AGEs 結合因子によるAGEs- RAGE結合抑制作用
- Author(s)
  森　秀治
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場（神戸市）
- Data Source
  KAKENHI-PROJECT-24590672
[Presentation] HMGB1，AGEs-RAGE系」に対する創薬プラットフォーム構築
- Author(s)
  森　秀治
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡市）
- Data Source
  KAKENHI-PROJECT-24590672

1. TOYOMURA Takao (40425137)

# of Collaborated Projects: 8 results

# of Collaborated Products: 10 results
2. Watanabe Masahiro (10758246)

# of Collaborated Projects: 7 results

# of Collaborated Products: 7 results
3. NISHIBORI Masahiro (50135943)

# of Collaborated Projects: 6 results

# of Collaborated Products: 37 results
4. TAKAHASHI Hideo (60335627)

# of Collaborated Projects: 6 results

# of Collaborated Products: 28 results
5. OKAMOTO Motoi (80144757)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. GOMITA Yutaka (00088709)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. WAKE HIDENORI (60570520)

# of Collaborated Projects: 2 results

# of Collaborated Products: 41 results
8. LIU Keyue (40432637)

# of Collaborated Projects: 2 results

# of Collaborated Products: 31 results
9. KATAOKA Masaroshi (20224438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. SHINOHARA Yasuo (60226157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. ISHIDA Tatsuhiro (50325271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MORI Hiroki (40388989)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
13. NAKANISHI Tohru (30243463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
14. ENDO Hiroshi (70033090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKATA Yasunari (80112150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TOGE Hiroko (10197840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KATAOKA Mikio (50177391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SAKIYAMA Junko (40204599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 菅家徹 (50432638)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大井治昭 (50223714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 白井敦 (20302226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 勅使川原匡 (40403737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
23. SADAMORI Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 丹羽淳子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 小堀宅郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 西中崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
27. ハティポールオメル・ファルク

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

MORI Shuji 森 秀治

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内因性ＡＧＥをコアとする組織リモデリング病態の増悪化機序解明と根治的治療法の開発Principal Investigator

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Elucidation of the mechanism of tissue remodeling exacerbated by endogenous AGEs and the development of novel targeted therapyPrincipal Investigator

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Study of the pathophysiological significance of endogenous AGE as an exacerbating factor for tissue remodeling, and the development of novel targeted therapyPrincipal Investigator

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Roles of AGEs as exacerbation factor in pathogenesis of tissue remodeling and the development of novel targeted therapyPrincipal Investigator

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Pathophysiological role of AGEs as exacerbation factor in tissue remodeling and molecular targeted therapyPrincipal Investigator

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Pathogenesis of tissue remodeling caused by endogenous AGE and advanced targeting therapyPrincipal Investigator

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MORI Shuji 森秀治