Ishida Tatsuhiro 石田竜弘

… Alternative Names

Researcher Number	50325271
Other IDs
Affiliation (Current)	2022: 徳島大学, 大学院医歯薬学研究部(薬学域), 教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 徳島大学, 大学院医歯薬学研究部(薬学域), 教授 2015 – 2017: 徳島大学, 大学院医歯薬学研究部(薬学系), 教授 2015: 徳島大学, 大学院医歯薬学研究部, 教授 2014: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授 2013 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 教授 … More
Review Section/Research Field	Principal Investigator Physical pharmacy / Medical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / 医薬分子機能学 Except Principal Investigator Basic Section 47060:Clinical pharmacy-related / Biological Sciences / Physical pharmacy / Drug development chemistry / Science and Engineering / Medium-sized Section 64:Environmental conservation measure and related fields / Basic Section 28030:Nanomaterials-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 90110:Biomedical engineering-related
Keywords	Principal Investigator リポソーム / DDS / がん治療 / ワクチン / 抗がん剤 / がん新生血管 / ナノキャリア / アジュバント / PEG / イオン液体 … More Except Principal Investigator リポソーム / DDS / RNAi創薬 / アルブミン / ドラッグデリバリーシステム / 膜タンパク質 / 試験管内タンパク質合成 / コートペプチド / 細胞機能模倣 / 再構成 / 高次構造 / フォールディング / 抗体 / プロテインA / 細胞機能の模倣 / マイクロチップ電気泳動 / ナノバイオデバイス / 合成ペプチド / マイクロファブリケーション / がん / 新生血管 / モデル動物 / 体内動態制御 / がん治療 / 抗がん剤 / 腫瘍内微小環境 / メトロノミック・ケモセラピー / ナノキャリア / 免疫系 / 抗PEG-IgM / B細胞 / ナノトキシコロジー / ポリエチレングリコール / 免疫反応 / ＤＤＳ / ＰＥＧ / ABC現象 / Anti-PEG IgM / 免疫活性化 / PEG / 4'-チオDNA / PCR / 非天然塩基対 / クリックケミストリー / 免疫応答 / 核酸創薬 / DNAデバイス / 化学合成 / バイオマス / 膵臓がん / ナノ粒子 / ナノセルロース / ネットワーク構造 / 腹膜播種 / 徐放 / 毒性低減 / 酸素移動容量係数 / 表面改質 / シランカップリング / グラフト化 / 開環重合 / 腹腔内滞留性向上 / 副作用低減 / 薬剤送達 / ボトムアップ / バイオリファイナリー / セルロース合成菌 / 高密度リポ蛋白質 / 動脈硬化 / 高密度リポタンパク質 / アポリポタンパク質 / アポリポタンタンパク質 / 脾臓免疫 / 抗体誘導 / エキソソーム / 膜タンパク / アルブミン受容体 / アクティブターゲティング / ワクチン / COVID-19 / コロナワクチン Less

高活性抗体の誘導を実現する抗原発現エキソソームの脾臓免疫技術基盤の構築
- Principal Investigator
  
  安藤英紀
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  The University of Tokushima
Development of albumin DDS carrier based on an understanding of the endogenous albumin transport system
- Principal Investigator
  
  異島優
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  The University of Tokushima
短時間高活性水熱前処理を用いた利益創出・エコ型バイオマス全成分有効利用法の開発
- Principal Investigator
  
  中村嘉利
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 64:Environmental conservation measure and related fields
- Research Institution
  The University of Tokushima
動脈硬化治療法の確立に向けたHDLリモデリングの分子基盤の解明とその応用
- Principal Investigator
  
  奥平桂一郎
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences
PEG修飾エクソソームを用いた脾臓辺縁体B細胞標的型コロナウイルスワクチンの開発Host Researcher
- Host Researcher
  
  石田竜弘
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokushima
Enhanced absorption drug delivery system by ionic liquidPrincipal Investigator
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
PEG修飾タンパクによるアナフィラキシー誘導機構の解明とその制御に関する研究Principal Investigator
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
Efficient anticancer drug delivery using a network structure of nanocellulose with a super high aspect ratio
- Principal Investigator
  
  田島健次
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 28030:Nanomaterials-related
- Research Institution
  Hokkaido University
Development of transdermal drug delivery system by ionic liquidPrincipal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
Development of novel multifunctional nanoparticles based on uptake mechanism of endogenous albumin by pancreatic cancer cells
- Principal Investigator
  
  ISHIMA Yu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  The University of Tokushima
Mannupulating inate immunity for new vaccine against cancer(Fostering Joint International Research)Principal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Development of nover antigen delivery system for tumor therapyPrincipal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Study of immunological response to nucleic acid delivery systemPrincipal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Investigation of practical anticancer strategy based on chemically synthesized iRed/iPed
- Principal Investigator
  
  MINAKAWA Noriaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokushima
Immunosuppression of anticancer agents containing PEGylated liposomes for liver transplantation.Principal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenvironment.Principal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Development of a novel RNAi medicine based on shRNA expression mini-plasmid
- Principal Investigator
  
  MINAKAWA Noriaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  The University of Tokushima
Anti-PEG Immunity upon nucleic acid delivery
- Principal Investigator
  
  KIWADA Hiroshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Development of novel vaccine system with nanocarrierPrincipal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
Evaluation on EPR effect and active control of EPR effect for achieving efficient tumor accumulation of nanocarrier delivery systemPrincipal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
腫瘍内微小環境変化を利用した新規DDSの開発
- Principal Investigator
  
  際田弘志
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Study for Interaction of Biological Milieu with Nano-drug Carrier system
- Principal Investigator
  
  KIWADA Hiroshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Application of liposomal anticancer drug for tumor dormant therapyPrincipal Investigator
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
がん新生血管を標的とした機能性リポソームによる革新的治療法の開発
- Principal Investigator
  
  KIWADA Hiroshi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Characterization of cell-free protein synthesis system and theapplication for the synthesis of cell membrane protein
- Principal Investigator
  
  KATAOKA Masaroshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Science and Engineering
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  The University of Tokushima
ナノベクター標的化による新生血管選択的遺伝子発現法の開発とそのがん治療への応用Principal Investigator
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
癌化学療法における多剤耐性の克服を目指した機能性リポソームの研究開発Principal Investigator
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  医薬分子機能学
- Research Institution
  The University of Tokushima

[Book] セルロースナノファイバー製造・利用の最新動向2019
- Author(s)
  田島健次、小瀬亮太、石田竜弘、松島得雄
- Total Pages
  10
- Publisher
  シエムシー出版
- ISBN
  9784781314044
- Data Source
  KAKENHI-PROJECT-19H02549
[Book] Cationic liposomes and tumour vasculature targeting : a therapeutic approach that has potential for solid tumours2011
- Author(s)
  Abu Lila A. S., Ishida T., Kiwada, H.
- Publisher
  i-Smithers-Creative Publishing Solutions
- Data Source
  KAKENHI-PROJECT-21689002
[Book] Breaking the barriers to tumor-targeting via nanocarrier-based drug delivery to the tumor microenvironment2010
- Author(s)
  Doi, Y., Ishida, T., Kiwada, H.
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-21689002
[Book] Unexpected reactions by in vivo application of PEGylated liposomes. "(Safety of Nanoparticles : From Manufacturing to Clinical Applications (A volume in the Nanostructure Science and Technology series))(T.J.Webster (Ed.)), Chapter 6, p111-1302009
- Author(s)
  Ishida, T., Kiwada, H.
- Publisher
  Springer Science + Business Media, New York, USA
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Therapeutic efficacy of a paclitaxel-loaded nanofibrillated bacterial cellulose (PTX/NFBC) formulation in a peritoneally disseminated gastric cancer xenograft model2021
- Author(s)
  Akagi Shunsuke、Ando Hidenori、Fujita Kenji、Shimizu Taro、Ishima Yu、Tajima Kenji、Matsushima Tokuo、Kusano Takatomo、Ishida Tatsuhiro
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 174 Pages: 494-501
- DOI
  10.1016/j.ijbiomac.2021.01.201
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H02549
[Journal Article] Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.2020
- Author(s)
  Ichimizu Shota、Watanabe Hiroshi、Maeda Hitoshi、Hamasaki Keisuke、Ikegami Komei、Chuang Victor Tuan Giam、Kinoshita Ryo、Nishida Kento、Shimizu Taro、Ishima Yu、Ishida Tatsuhiro、Seki Takahiro、Katsuki Hiroshi、Futaki Shiroh、Otagiri Masaki、Maruyama Toru
- Journal Title
  
  J Control Release.
  
  Volume: 304 Pages: 156-163
- DOI
  10.1016/j.jconrel.2019.05.015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K07123, KAKENHI-PROJECT-16H04673, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604
[Journal Article] Albumin domain mutants with enhanced Aβ binding capacity identified by phage display analysis for application in various peripheral Aβ elimination approaches of Alzheimer's disease treatment2020
- Author(s)
  Ishima Yu、Mimono Ai、Tuan Giam Chuang Victor、Fukuda Tetsuya、Kusumoto Kohshi、Okuhira Keiichiro、Suwa Yoshiaki、Watanabe Hiroshi、Ishida Tatsuhiro、Morioka Hiroshi、Maruyama Toru、Otagiri Masaki
- Journal Title
  
  IUBMB Life.
  
  Volume: 72 Pages: 641-651
- DOI
  10.1002/iub.2203
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-20H04124
[Journal Article] Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice2020
- Author(s)
  Elsadek Nehal E.、Abu Lila Amr S.、Emam Sherif E.、Shimizu Taro、Takata Haruka、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics
  
  Volume: 152 Pages: 56-62
- DOI
  10.1016/j.ejpb.2020.04.026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279
[Journal Article] Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon.2020
- Author(s)
  El Sayed, M.M., Takata, H., Shimizu, T., Kawaguchi, Y., Abu Lila, A.S., Elsadek, N.E., Alaaeldin, E., Ishima, Y., Ando, H., Kamal, A., Sarhan, H.A., Ishida, T.
- Journal Title
  
  J. Conrol. Release
  
  Volume: 323 Pages: 102-109
- DOI
  10.1016/j.jconrel.2020.04.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279
[Journal Article] S-Nitrosated alpha-1-acid glycoprotein exhibits antibacterial activity against multidrug-resistant bacteria strains and synergistically enhances the effect of antibiotics2019
- Author(s)
  Ishima Yu、Watanabe Kaori、Chuang Victor T. G.、Takeda Iyo、Kuroda Teruo、Ogawa Wakano、Watanabe Hiroshi、Iwao Yasunori、Ishida Tatsuhiro、Otagiri Masaki、Maruyama Toru
- Journal Title
  
  FASEB Bioadv
  
  Volume: 1 Pages: 137-150
- DOI
  10.1096/fba.1018
- NAID
  120007153321
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604
[Journal Article] ナノフィブリル化バクテリアセルロース（Fibnano)を用いた腹腔内投与型がん治療製剤への応用2019
- Author(s)
  安藤英紀、田島健次、松島得雄、石田竜弘
- Journal Title
  
  Cellulose Communications
  
  Volume: 26 Pages: 173-177
- NAID
  40022090343
- Data Source
  KAKENHI-PROJECT-19H02549
[Journal Article] Distribution of polysulfide in human biological fluids and their association with amylase and sperm activities2019
- Author(s)
  Ikeda Mayumi、Ishima Yu、Chuang Victor T. G.、Sakai Maki、Osafune Hiroki、Ando Hidenori、Shimizu Taro、Okuhira Keiichiro、Watanabe Hiroshi、Maruyama Toru、Otagiri Masaki、Akaike Takaaki、Ishida Tatsuhiro
- Journal Title
  
  Molecules
  
  Volume: 24 Pages: 1689-1689
- DOI
  10.3390/molecules24091689
- NAID
  120006995454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-18H05277
[Journal Article] フルーツ由来新奇酢酸菌によるナノセルロースの合成とその応用2019
- Author(s)
  田島健次、小瀬亮太、松島得雄、石田竜弘、安藤英紀
- Journal Title
  
  日本醸造協会誌
  
  Volume: 114 Pages: 540-549
- NAID
  40022026601
- Data Source
  KAKENHI-PROJECT-19H02549
[Journal Article] Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: Unique surface properties underlying alternative pathway activation and instant opsonization.2018
- Author(s)
  Meszaros, T., Kozma, G., Shimizu, T., Miyahara, K., Turjeman, K., Ishida, T., Barenholz, Y., Urbanics, R., Szebeni, J.
- Journal Title
  
  Int. J. Nanomed.
  
  Volume: 13 Pages: 6345-6357
- DOI
  10.2147/ijn.s161369
- NAID
  120006956857
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0310
[Journal Article] Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens2018
- Author(s)
  8.Ando, H., Abu Lila, A.S., Kawanishi, M., Shimizu, T., Okuhira, K., Ishima, Y., Ishida, T.
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 270 Pages: 114-119
- DOI
  10.1016/j.jconrel.2017.12.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639, KAKENHI-PROJECT-16K15108, KAKENHI-PROJECT-16K08236
[Journal Article] A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis.2018
- Author(s)
  Ikeda M, Ishima Y, Kinoshita R, Chuang VTG, Tasaka N, Matsuo N, Watanabe H, Shimizu T, Ishida T, Otagiri M, Maruyama T,
- Journal Title
  
  Redox Biol.
  
  Volume: 14 Pages: 354-360
- DOI
  10.1016/j.redox.2017.10.007
- NAID
  120007029979
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
[Journal Article] Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity2018
- Author(s)
  Tanaka KI, Shimoda M, Chuang VTG, Nishida K, Kawahara M, Ishida T, Otagiri M, Maruyama T, Ishima Y.
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 535 Pages: 140-147
- DOI
  10.1016/j.ijpharm.2017.11.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-18H02587
[Journal Article] Development of kupffer cell targeting type-Ⅰ interferon for the treatment of hepatitis via Inducing anti-inflammatory and immunomodulatory actions2018
- Author(s)
  Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.
- Journal Title
  
  Drug Deliv.
  
  Volume: 25 Pages: 1055-1065
- DOI
  10.1080/10717544.2018.1464083
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-17K15511, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02798
[Journal Article] Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.2018
- Author(s)
  Ichimizu Shota、Watanabe Hiroshi、Maeda Hitoshi、Hamasaki Keisuke、Nakamura Yuka、Chuang Victor Tuan Giam、Kinoshita Ryo、Nishida Kento、Tanaka Ryota、Enoki Yuki、Ishima Yu、Kuniyasu Akihiko、Kobashigawa Yoshihiro、Morioka Hiroshi、Futaki Shiro、Otagiri Masaki、Maruyama Toru
- Journal Title
  
  J. Control. Release.
  
  Volume: 277 Pages: 23-34
- DOI
  10.1016/j.jconrel.2018.02.037
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08383, KAKENHI-PROJECT-15K14983, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17H04105, KAKENHI-PROJECT-18H02587
[Journal Article] Dual Therapeutic Effects of an Albumin-Based Nitric Oxide Donor on 2 Experimental Models of Chronic Kidney Disease.2018
- Author(s)
  Oshiro S, Ishima Y, Maeda H, Honda N, Bi J, Kinoshita R, Ikeda M, Iwao Y, Imafuku T, Nishida K, Miyamura S, Watanabe H, Otagiri M, Maruyama T
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 107 Pages: 140-147
- DOI
  10.1016/j.xphs.2017.10.023
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-16K15320, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
[Journal Article] Intratumoral Visualization of Oxaliplatin within a Liposomal Formulation Using X-ray Fluorescence Spectrometry2018
- Author(s)
  5.Ando, H., Abu Lila, A.S., Tanaka, M., Doi, Y., Terada, Y., Yagi, N., Shimizu, T., Okuhira, K., Ishima, Y., Ishida, T.,
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 15 Pages: 403-409
- DOI
  10.1021/acs.molpharmaceut.7b00762
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639, KAKENHI-PROJECT-16K08236
[Journal Article] Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity.2017
- Author(s)
  Mima, Y., Abu Lila, A.S., Shimizu, T., Ukawa, M., Ando, H., Kurata, Y., Ishida, T.
- Journal Title
  
  J. Control Release
  
  Volume: 250 Pages: 20-26
- DOI
  10.1016/j.jconrel.2017.01.040
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.2017
- Author(s)
  17.Abu Lila, A.S., Moriyoshi, N., Fukushima, M., Huang, C., Wada, H., Ishida, T.
- Journal Title
  
  Cancer Letters
  
  Volume: 400 Pages: 223-231
- DOI
  10.1016/j.canlet.2016.11.005
- NAID
  120006894605
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.2017
- Author(s)
  11.Shimizu, T., Abu Lila, A.S., Nishio, M., Doi, Y., Ando, H., Ukawa, M., Ishima, Y., Ishida, T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Pages: 1864-1869
- DOI
  10.1111/cas.13305
- NAID
  120006535002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules.2017
- Author(s)
  12.Alaaeldin, E., Abu Lila, A.S., Ando, H., Fukushima, M., Huang, C., Wada, H., Sarhan, H.A., Khaled, K.A., Ishida, T.
- Journal Title
  
  J. Control Release
  
  Volume: 255 Pages: 210-217
- DOI
  10.1016/j.jconrel.2017.04.040
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.2016
- Author(s)
  Abu Lila, A.S., Kato, C., Fukushima, M., Huang, C., Wada, H., Ishida, T.
- Journal Title
  
  Int. J. Oncol.
  
  Volume: 48 Pages: 1399-1407
- DOI
  10.3892/ijo.2016.3367
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Gene silencing using 4'-thioDNA as an artificial template to synthesize short-hairpin RNA without inducing a detectable innate immune response2016
- Author(s)
  Noriko Tarashima, Hidenori Ando,Takamitsu Kojima,Nozomi Kinjo,Yosuke Hashimoto,Kazuhiro Furukawa,Tatsuhiro Ishida, Noriaki Minakawa
- Journal Title
  
  Mol. Ther. Nucl. Acids
  
  Volume: 5
- DOI
  10.1038/mtna.2015.48
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04656, KAKENHI-PROJECT-15H06446
[Journal Article] Anti-PEG IgM is a major contributor to the accelerated blood clearance of polyethylene glycol-conjugated protein.2015
- Author(s)
  Mima, Y., Hashimoto, Y., Shimizu, T., Kiwada, H., Ishida, T.
- Journal Title
  
  Mol. Pharmaceutics
  
  Volume: 12 Pages: 2429-2435
- DOI
  10.1021/acs.molpharmaceut.5b00144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670079
[Journal Article] Synthesis of DNA fragments containing 2’-deoxy-4’-selenonucleoside units using DNA polymerases: comparison of dNTPs with O, S and Se at the 4’-position in replication.2015
- Author(s)
  Noriko Tarashima, Tatsuya Sumitomo, Hidenori Ando, Kazuhiro Furukawa, Tatsuhiro Ishida and Noriaki Minakawa*
- Journal Title
  
  Org. Biomol. Chem.
  
  Volume: 13 Pages: 6949-6952
- DOI
  10.1039/c5ob00941c
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04656, KAKENHI-PROJECT-15H06446, KAKENHI-PROJECT-26630432
[Journal Article] Comprehensive analysis of PEGylated liposome-asscociated proteins relating to the accelerated blood clearance phenomenon by combination with shotgun analysis and conventional methods.2015
- Author(s)
  Kawanishi, M., Hashimoto, Y., Shimizu, T., Sagawa, I., Ishida, T., Kiwada, H.
- Journal Title
  
  Biotech. Appl. Biochem.
  
  Volume: 62 Pages: 547-555
- DOI
  10.1002/bab.1291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670079
[Journal Article] Sequential treatment of oxaliplatin-containing PEGylated liposome together with S-1 improves intratumor distribution of subsequent doses of oxaliplatin-containing PEGylated liposome.2014
- Author(s)
  Nakamura, H., Doi, Y., Abu Lila, A.S., Nagao, A., Ishida, T., Kiwada, H
- Journal Title
  
  Eur. J. Pharm. Biopharm.
  
  Volume: 87 Pages: 142-151
- DOI
  10.1016/j.ejpb.2013.12.007
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390010
[Journal Article] Application of polyglycerol-coating to pDNA lipoplex for the evasion of the accelerated blood clearance (ABC) phenomenon in nucleic acid delivery.2014
- Author(s)
  Abu Lila, A.S., Uehara, Y., Ishida, T., Kiwada, H
- Journal Title
  
  J. Pharm. Sci.
  
  Volume: 103 Pages: 557-566
- DOI
  10.1002/jps.23823
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Influence of dose and animal species on accelerated blood clearance of PEGylated liposomal doxorubicin.2014
- Author(s)
  Suzuki, T., Ichihara, M., Hyodo, K., Yamamoto, E., Ishida, T., Kiwada, H., Kikuchi, H., Ishihara, H.
- Journal Title
  
  Int. J. Pharm
  
  Volume: 476 Pages: 205-212
- DOI
  10.1016/j.ijpharm.2014.09.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390010
[Journal Article] B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice2014
- Author(s)
  Hashimoto, Y., Abu Lila A., Shimizu, T., Ishida, T., Kiwada, H
- Journal Title
  
  J. Control. Release
  
  Volume: 184C Pages: 1-8
- DOI
  10.1016/j.jconrel.2014.04.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs.2014
- Author(s)
  Hashimoto Y., Shimizu T., Mima Y., Abu Lila A., Ishida T., Kiwada H
- Journal Title
  
  Toxicol. Appl. Pharmacol.
  
  Volume: 277 Pages: 30-38
- DOI
  10.1016/j.taap.2014.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage.2013
- Author(s)
  Abu Lila, A.S., Kiwada, H., Ishida, T.
- Journal Title
  
  J. Control. Release
  
  Volume: 172 Pages: 38-47
- DOI
  10.1016/j.jconrel.2013.07.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] The co-delivery of oxaliplatin abrogates the immunogenic response to PEGylated siRNA-lipoplex.2013
- Author(s)
  Alaaeldin, E.,, Abu Lila, A.S., Moriyoshi, N., Sarahan, H.A., Ishida, T., Khaled A. Khale, Kiwada, H
- Journal Title
  
  Pharm. Res.
  
  Volume: 30 Pages: 2344-2354
- DOI
  10.1007/s11095-013-1078-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Abrogation of the accelerated blood clearance phenomenon by SOXL regimen : Promise for clinical application2013
- Author(s)
  Nagao, A., Abu Lila, A.S., Ishida, T, Kiwada, H
- Journal Title
  
  Int. J. Pharm
  
  Volume: 441 Pages: 395-401
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Ex-vivo/in-vitro anti-polyethylene Glycol (PEG) IgM production from murine splenic B cells stimulated by PEGylated liposome.2013
- Author(s)
  Abu Lila, A.S., Ichihara, M., Shimizu, T., Ishida, T., Kiwada, H.
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 36 Pages: 1842-1848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Transport of PEGylated liposomes from the splenic marginal zone to the follicle in the induction phase of the accelerated blood clearance phenomenon2013
- Author(s)
  Shimizu T
- Journal Title
  
  Immunobiol
  
  Volume: 218 Pages: 725-732
- DOI
  10.1016/j.imbio.2012.08.274
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012, KAKENHI-PROJECT-23659082
[Journal Article] Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration.2013
- Author(s)
  Abu Lila, A.S., Nawata, K., Shimizu, T., Ishida, T., Kiwada, H.
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 456 Pages: 235-242
- DOI
  10.1016/j.ijpharm.2013.07.059
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Accelerated blood clearance of PEGylated liposomes containing doxorubicin upon repeated administration to dogs.2012
- Author(s)
  Suzuki, T., Ichihara, M., Hyodo, K., Yamamoto, E., Ishida, T., Kiwada, H., Ishihara, H., Kikuchi, H
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 436 Pages: 636-643
- DOI
  10.1016/j.ijpharm.2012.07.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model2012
- Author(s)
  Tagami, T., Abu Lila, A. S., Matsunaga, M., Moriyoshi, N., Nakamura, H., Nakamura, K., Suzuki, T., Doi, Y., Ishida, T., Kiwada, H.
- Journal Title
  
  Drug Deliv. Transl. Res.
  
  Volume: 2 Pages: 77-86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model : Synergy or antagonism?2012
- Author(s)
  Abu Lila, A. S., Okada, T., Doi, Y., Ichihara, M., Ishida, T., Kiwada, H.
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 426 Pages: 263-270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Anti-PEG IgM response against PEGylated liposomes in mice and rats.2011
- Author(s)
  Ichihara M., Shimizu T., Imoto A., Hashiguchi Y., Uehara Y., Ishida T, Kiwada H.
- Journal Title
  
  Pharmaceutics in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA2011
- Author(s)
  Tagami T., Uehara Y., Moriyoshi N., Ishida T., Kiwada H
- Journal Title
  
  J. Control. Release
  
  Volume: 151 Pages: 149-154
- DOI
  10.1016/j.jconrel.2010.12.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390012
[Journal Article] Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA.2011
- Author(s)
  Tagami T., Uehara Y., Moriyoshi N., Ishida T., Kiwada H.
- Journal Title
  
  J.Control.Release in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] A double-modulation strategy in cancer treatment with a chemotherapeutic agent and siRNA2011
- Author(s)
  Nakamura, K, Abu Lila A., Matsunaga, M., Doi, Y., Ishida, T., Kiwada, H.
- Journal Title
  
  Mol. Ther.
  
  Volume: 19 Pages: 2040-2047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Evasion of the accelerated blood clearance phenomenon by coating of nanoparticles with various hydrophilic polymers.2010
- Author(s)
  Ishihara T., Maeda T., Sakamoto H., Takasaki N., Shigyo M., Ishida T., Kiwada H., Mizushima Y., Mizushima T.
- Journal Title
  
  Biomacromolecules 11
  
  Pages: 2700-2706
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] CpG motifs in pDNA-sequences increase anti-PEG IgM production induced by PEG-coated pDNA-lipoplexes.2010
- Author(s)
  Tagami, T., Nakamura, K., Shimizu, T., Yamazaki, N., Ishida, T., Kiwada, H.
- Journal Title
  
  J.Control.Release 142
  
  Pages: 160-166
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer.2010
- Author(s)
  Eto Y., Yoshioka Y., Ishida T., Yao X., Morishige T., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Kiwada H., Nakagawa S.
- Journal Title
  
  Biol.Pharm.Bull. 25
  
  Pages: 149-154
- NAID
  130000322353
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Sequential administration with oxaliplatin-containing PEG-coated cationic liposomes promotes a significant delivery of subsequent dose into murine solid tumor2010
- Author(s)
  Abu Lila, A., Doi, Y., Nakamura, K., Ishida, T., Kiwada, H.
- Journal Title
  
  J. Control. Release
  
  Volume: 142 Pages: 167-173
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Combination therapy of metronomic S-1 dosing with oxaliplatin-containing PEG-coated liposome improves antitumor activity in a murine colorectal tumor model2010
- Author(s)
  Doi Y., Okada T., Matsumoto H., Ichihara M., Ishida T., Kiwada, H.
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 2470-2475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes.2010
- Author(s)
  Koide H., Asai, T., Hatanaka, K., Akai, S., Ishii, T., Kenjo, E., Ishida, T., Kiwada, H., Tsukada, H., Oku, N.
- Journal Title
  
  Int.J.Pharm. 392
  
  Pages: 218-223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Targeting anticancer drugs to tumor vasculature using cationic liposomes2010
- Author(s)
  Abu Lila, A., Ishida, T., Kiwada, H.
- Journal Title
  
  Pharm. Res.
  
  Volume: 27 Pages: 1171-1183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model.2009
- Author(s)
  Abu-Lila, A, Suzuki, T., Doi. Y. Ishida, T., Kiwada, H.,
- Journal Title
  
  J. Control. Release, 134
  
  Pages: 18-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] Recent advances in tumor vasculature targeting using liposomal drug delivery systems2009
- Author(s)
  Abu Lila, A., Ishida, T., Kiwada, H.
- Journal Title
  
  Expert Opin. Drug Deliv.
  
  Volume: 6 Pages: 1297-1309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model2009
- Author(s)
  Ishida, T.
- Journal Title
  
  J. Control. Release 134
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] Accelerated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles.2009
- Author(s)
  Ishihara, T., Takeda, M., Sakamoto, H., Kimoto, A., Kobayashi, C., Takasaki, N., Yuki, K., Tanaka, K., Takenaga, M., Igarashi, R., Maeda, T., Yamakawa, N., Okamoto, Y., Otsuka, M., Ishida, T., Kiwada, H.
- Journal Title
  
  Pharm.Res. 26
  
  Pages: 2270-2279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model.2009
- Author(s)
  Ishida, T.
- Journal Title
  
  J.Control. Release 134
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model2009
- Author(s)
  Ishida, T.
- Journal Title
  
  J. Control. Release 134
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015033
[Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model.2009
- Author(s)
  Ishida, T., Shiraga, E., Kiwada, H.,
- Journal Title
  
  J. Control. Release 134
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model2009
- Author(s)
  Abu Lila, A., Kizuki, S., Doi, Y., Suzuki, T., Ishida, T., Kiwada, H.
- Journal Title
  
  J. Control. Release
  
  Volume: 137 Pages: 8-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model2009
- Author(s)
  Ishida, T., Shiraga, E., Kiwada, H.
- Journal Title
  
  J. Control. Release
  
  Volume: 134 Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model2009
- Author(s)
  Abu-Lila, A, Suzuki, T., Doi, Y., Ishida, T., Kiwada, H.
- Journal Title
  
  J. Control. Release
  
  Volume: 134 Pages: 18-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689002
[Journal Article] Effect of siRNA in PEG-coated siRNA-lipoplex on anti-PEG IgM production.2009
- Author(s)
  Tagami, T., Nakamura, K., Shimizu, T., Ishida, T., Kiwada, H.
- Journal Title
  
  J.Control.Release 137
  
  Pages: 234-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] A metronomic schedule of cyclophosphamide combined with PEGylated liposomal doxorubicin has a highly antitumor effect in an experimental pulmonary metastatic mouse model.2008
- Author(s)
  Shiraga, E., Barichello, J.M., Ishida, T., Kiwada, H.,
- Journal Title
  
  Int. J. Pharm., 353
  
  Pages: 65-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats.2008
- Author(s)
  Ishida, T., et al.
- Journal Title
  
  J. Control. Release 126
  
  Pages: 162-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes.2008
- Author(s)
  Ishida, T., Kiwada, H.
- Journal Title
  
  Int.J.Pharm. 354
  
  Pages: 56-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Disappearance of the angiogenic potential of endothelial cells caused by Argonaute2 knockdown.2008
- Author(s)
  Suzuki, Y., Matsushita, S., Yonezawa, S., Yokota, J., Katanasaka, Y. Ishida, T., Dcwa, T., Kiwada,, H., Nango, N., Oku, N.,
- Journal Title
  
  Biochem. Biophys. Res. Commun., 368
  
  Pages: 243-248
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats.2008
- Author(s)
  Ishida, T., Kashima, S., Kiwada, H.
- Journal Title
  
  J.Control.Release 126
  
  Pages: 162-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Particle size-dependent triggering of accelerated blood clearance phenomenon.2008
- Author(s)
  Koide H., Asai, T., Hatanaka, K., Urakami, T., Ishii, T., Kenjo, E., Nishihara, M., Yokoyama, M., Ishida, T., Kiwada, H., Oku, N.
- Journal Title
  
  Int.J.Pharm. 362
  
  Pages: 197-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390013
[Journal Article] Tumor targeting of doxorubicin by and MT1-MMP antibody-modified PEG liposomes.2007
- Author(s)
  Hatakeyama, H., Akita, H., Ishida, E., Hashimoto, K., Kobayashi, H., Aoki, T., Yasuda, J., Obata, K., Kikuchi, K., Ishida, T., Kiwada, H., Harashima, H.,
- Journal Title
  
  Int. J. Pharm., 342
  
  Pages: 194-200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] PEGylated liposomes elicit an anti-PEG IgM response in a T-cells independent manner.2007
- Author(s)
  Ishida, T., et. al.
- Journal Title
  
  J. Control. Release 122
  
  Pages: 349-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18015036
[Journal Article] In vitro efficacy of a sterically stabilized immunoliposomes targeted to membrane type 1 matrix metalloproteinase (MT1-MMP).2007
- Author(s)
  Atobe K., Ishida T., Ishida, E., Hashimoto K., Kobayashi H., Yasuda J., Aoki, T, Obata K, Kikuchi H., Akita, H., Asai, T, Harashima, H., Oku, N., Kiwada, H.,
- Journal Title
  
  Biol. Pharm. Bull., 30
  
  Pages: 972-978
- NAID
  110006273300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790128
[Journal Article] Spleen plays an important role in the induction of accelerated blood clearance o PEGylated liposomes.2006
- Author(s)
  Ishida, T., et al.
- Journal Title
  
  Journal of Controlled Release 115
  
  Pages: 243-250
- Data Source
  KAKENHI-PROJECT-18015036
[Journal Article] Development of pH-sensitive liposomes that efficiently retain encapsulated doxorubicin (DXR) in blood.2006
- Author(s)
  Ishida, T., et al.
- Journal Title
  
  International Journal of Pharmaceutics 309
  
  Pages: 94-100
- Data Source
  KAKENHI-PROJECT-18015036
[Journal Article] Injection of PEGylated liposomes in rats elicits PEG-secifc IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes.2006
- Author(s)
  Ishida T., et al.
- Journal Title
  
  Journal of Controlled Release 112
  
  Pages: 15-25
- Data Source
  KAKENHI-PROJECT-18015036
[Journal Article] Development of pH-sensitive liposomes that efficiently retain encapsulated doxorubicin (DXR) in blood.2006
- Author(s)
  Tatsuhiro Ishida
- Journal Title
  
  International Journal of Pharmaceutics 309
  
  Pages: 94-100
- Data Source
  KAKENHI-PROJECT-16790105
[Journal Article] Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodynamics-based transfection.2006
- Author(s)
  Ishida, T., et al.
- Journal Title
  
  Journal of Gene Medicine 8
  
  Pages: 324-334
- Data Source
  KAKENHI-PROJECT-18015036
[Patent] リポソームに抗体結合能を付与するペプチド、および当該ペプチドで修飾されたリボソーム2007
- Inventor(s)
  篠原康雄、際田弘志、石田竜弘、山崎尚志, 片岡正俊
- Industrial Property Rights Holder
  国立大学法人徳島大学、独立行政法人産業技術総合研究所
- Industrial Property Number
  2007-288728
- Filing Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-17076011
[Patent] リポソームに抗体結合能を付与するペプチド、および当該ペプチドで修飾されたリポソーム2007
- Inventor(s)
  片岡正俊、篠原康雄、際田弘志、石田竜弘、山崎尚志
- Industrial Property Rights Holder
  産総研徳島大学
- Industrial Property Number
  2007-288728
- Filing Date
  2007-11-06
- Data Source
  KAKENHI-PROJECT-17076011
[Presentation] イオン液体を用いたGLP-1受容体作動薬の腸管吸収性検討2021
- Author(s)
  角南尚哉、安藤英紀、丸山敦也、三輪泰司、濱本英利、清水太郎、異島優、石田竜弘
- Organizer
  日本薬学会第141年会（Web開催）
- Data Source
  KAKENHI-PROJECT-20K21898
[Presentation] 免疫抑制剤フィンゴリモドがマクロファージへの脂質蓄積に与える影響2021
- Author(s)
  立花洸季、小川真依、石田竜弘、異島優、奥平桂一郎
- Organizer
  日本薬学会　第141年会
- Data Source
  KAKENHI-PROJECT-20H04124
[Presentation] Immunological response to PEGylated liposomes: production of anti-PEG antibodies and their affection on PK of second dose.2019
- Author(s)
  Ishida, T.
- Organizer
  17th International Symposium on Blood Substitutes & Oxygen Therapeutics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279
[Presentation] 難治性膵臓がんにおけるアルブミンナノ粒子のサイズ最適化の検討2019
- Author(s)
  異島優、木下遼、平川尚樹、石田竜弘、小田切優樹、丸山徹
- Organizer
  第30回日本消化器癌発生学会総会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 難治性膵臓がんへの高い移行性を有するアルブミンナノ粒子の開発2019
- Author(s)
  平川尚樹、異島優、木下遼、清水太郎、丸山徹、奥平桂一郎、石田竜弘
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 両親媒性ナノフィブリル化バクテリアセルロース（Fibnano）の放出制御型がん治療製剤への応用2019
- Author(s)
  赤木俊介、安藤英紀、田島健次、松島得雄、草野貴友、石田竜弘
- Organizer
  セルロース学会第26回年次大会
- Data Source
  KAKENHI-PROJECT-19H02549
[Presentation] 腫瘍ターゲティングとEPR効果2019
- Author(s)
  石田竜弘
- Organizer
  日本薬物動態学会第34回年会（茨城、つくば国際会議場）
- Invited
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] 細胞膜透過型アルブミンの細胞内移行機序の解明～マクロピノサイトーシス誘導とエンドソーム脱出経路～2019
- Author(s)
  一水翔太、渡邊博志、前田仁志、清水太郎、異島優、石田竜弘、二木史朗、小田切優樹、丸山徹
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 両親媒性ナノフィブリル化バクテリアセルロースを基剤とした放出制御型Paclitaxel製剤の開発2019
- Author(s)
  赤木俊介、安藤英紀、田島健次、松島得雄、草野貴友、石田竜弘
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-19H02549
[Presentation] 抗体医薬を用いたがん治療に対するEPR増強剤SNO-HSA-dimerの効果2019
- Author(s)
  異島優、木下遼、池田真由美、丸山徹、小田切優樹、石田竜弘
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 血清アルブミンの酸化ストレス応答を模倣した新規抗酸化剤の設計2019
- Author(s)
  池田真由美、異島優、清水太郎、安藤英紀、奥平桂一郎、渡邊博志、丸山徹、小田切優樹、石田竜弘
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] Functional Elucidation of Polysulfides In Serum Albumin and Development of Biomimetic Donor of Polysulfides.2019
- Author(s)
  Ikeda, M., Ishima, Y., Watanabe, H., Maruyama, T., Otagiri, M., Ishida, T.
- Organizer
  2019 CRS Annual Meeting & Exposition.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 物理化学的性質の異なるナノフィブリル化バクテリアセルロース（NFBC）を用いたPTX製剤の開発とがん治療評価2019
- Author(s)
  赤木俊介、安藤英紀、田島健次、松島得雄、草野貴友、石田竜弘
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-19H02549
[Presentation] イオン液体を用いた新規インスリン含有経皮吸収製剤は糖尿病治療薬になりうる2019
- Author(s)
  佐々井雅樹、清水太郎、奥平桂一郎、異島優、石橋賢樹、三輪泰司、濱本英利、石田竜弘
- Organizer
  第28回DDSカンファランス（静岡、グランシップ）
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] ヒト血清アルブミンに存在するポリスルフィドによるユニークな酸化ストレス応答2019
- Author(s)
  池田真由美、異島優、酒井真紀、清水太郎、安藤英紀、渡邊博志、丸山徹、小田切優樹、石田竜弘
- Organizer
  第19回日本NO学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] PEG修飾リポソームに対する免疫反応（ABC現象）の解明とワクチンへの応用2018
- Author(s)
  石田竜弘
- Organizer
  日本薬学会北海道支部・特別講演会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] 新規腫瘍DDSキャリアである共有結合型アルブミンナノ粒子の有用性評価2018
- Author(s)
  木下遼、異島優、渡邊博志、清水太郎、石田竜弘、小田切優樹、丸山徹
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] ポリスルフィド付加血清アルブミンによるメラニン産生の抑制2018
- Author(s)
  池田真由美、清水太郎、丸山徹、小田切優樹、異島優、石田竜弘
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 一酸化窒素を利用した血管透過性制御とがん治療応用2018
- Author(s)
  異島優、木下遼、池田真由美、丸山徹、小田切優樹、石田竜弘
- Organizer
  日本薬学会第139年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 生物由来健康食品に含まれる活性イオウ分子種の検出2018
- Author(s)
  長船裕輝、池田真由美、酒井真紀、清水太郎、異島優、石田竜弘
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 共有結合型アルブミンナノ粒子を用いたセラノスティックナノDDS抗がん剤の開発2018
- Author(s)
  平川尚樹、異島優、木下遼、清水太郎、丸山徹、奥平桂一郎、石田竜弘
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] アルブミン製剤中のサルフェン硫黄含有量の差異と抗酸化能の評価2018
- Author(s)
  酒井真紀、池田真由美、今福匡司、清水太郎、丸山徹、小田切優樹、異島優、石田竜弘
- Organizer
  第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] A Novel S-Sulfhydrated Human Serum Albumin Preparation Suppresses Melanin Synhtesis.2018
- Author(s)
  Ikeda, M., Tasaka, N., Shimizu, T., Ishima, Y., Ishida, T.
- Organizer
  5th World Congress on Hydrogen Sulfide in Biology&Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 多剤耐性菌および真菌に対するS‐ニトロソ化Alpha1―酸性糖蛋白質の効果2018
- Author(s)
  異島優、石田竜弘, 金城雄樹、丸山徹、小田切優樹
- Organizer
  医療薬学フォーラム 2018
- Invited
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 共有結合型アルブミンナノ粒子をキャリアとしたナノDDS抗がん剤の開発及び有用性評価2018
- Author(s)
  平川尚樹、木下遼、異島優、清水太郎、丸山徹、奥平桂一郎、石田竜弘
- Organizer
  第34回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] Immunological responses against PEGylated liposomes: Application for cancer vaccine.2018
- Author(s)
  Ishida, T.
- Organizer
  13th France-Japan Drug Delivery Systems Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] 生体液中の活性イオウ分子種の検出と機能解明2018
- Author(s)
  池田真由美、異島優、渡邊博志、赤池孝章、丸山徹、小田切優樹、石田竜弘
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 新規抗菌剤SNO-AGPの多剤耐性菌に対する克服効果2018
- Author(s)
  異島優、渡辺佳織、小田切優樹、石田竜弘、丸山徹
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H02587
[Presentation] 微粒子製剤に対する免疫反応：PEG修飾リポソームに対するABC現象とCARPA2018
- Author(s)
  石田竜弘
- Organizer
  製剤種差検討会第7回事例報告会
- Invited
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] Anti-polyethylene-glycol Antibody Response to PEGylated Nanoparticles.2018
- Author(s)
  Ishida, T.
- Organizer
  CLINAM summit 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15KK0310
[Presentation] Immunological responses against PEGylated liposomes: the application of ABC phenomenon into cancer vaccine.2018
- Author(s)
  Ishida, T., Shimizu, T.
- Organizer
  12th International Symposium on Nanomedicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] Immunological responses against PEGylated materials: the accelerated blood clearance (ABC) issue.2017
- Author(s)
  Ishida, T.
- Organizer
  International Symposium on Nanomedicine 2017
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] 化学修飾DNAを利用したRNA創薬2017
- Author(s)
  南川典昭、田良島典子、高橋知樹、山本清義、金城望、安藤英紀、石田竜弘、小暮健太朗
- Organizer
  第33回日本DDS学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04656
[Presentation] 補体活性化能を持つポリマー修飾リポソームによる脾臓辺縁帯B細胞標的化に関する検討2017
- Author(s)
  清水太郎、粟田瑞月、吉岡千尋、異島優、石田竜弘
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] 脾臓辺縁帯B細胞標的化能をもつポリマー修飾リポソームを用いた静注型ワクチン開発に関する検討2017
- Author(s)
  吉岡千尋、粟田瑞月、渡辺優希、清水太郎、石田竜弘
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] Immunological response to PEGylated nanoparticles: Anti-PEG antibody issues.2017
- Author(s)
  Ishida, T.
- Organizer
  ILS Liposome Advances and Liposome Research Days Combined Conference.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] リポソーム化抗がん剤投与が引き起こす腫瘍免疫細胞の影響2016
- Author(s)
  高山拓磨、清水太郎、鵜川真実、石田竜弘
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] Anti-PEG immunity against PEGylated materials.2016
- Author(s)
  Ishida, T.
- Organizer
  International Workshop for Immune Effects of Nanomedicines: Clinical and Experimental Evidence, Prediction and Prevention.
- Place of Presentation
  Budapest, Hungary
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] PEG修飾有機シリカ粒子に対する免疫応答に関する検討2016
- Author(s)
  中見祥一、清水太郎、中村教泰、石田竜弘
- Organizer
  第５５回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  就実大学薬学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] Development of a RNAi-based anticancer drug.2016
- Author(s)
  Ishida, T.
- Organizer
  12th France-Japan Drug Delivery Systems Symposium
- Place of Presentation
  Paris, France
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] ヒトにおける抗PEG抗体保有率の調査2016
- Author(s)
  清水太郎、久保幸代、石田竜弘
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] 抗がん剤封入リポソームとの併用によるがんワクチン効果の増強に関する検討2016
- Author(s)
  竹瀬俊輔、高山拓磨、西尾美穂、清水太郎、石田竜弘
- Organizer
  第５５回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  就実大学薬学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] ポリエチレングリコール修飾タンパク製剤Pegasysに対する抗PEG IgM応答2016
- Author(s)
  本藤栄里、美馬優、清水太郎、石田竜弘
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] PEGリポソームへのアルブミン修飾は、抗PEG抗体の産生を抑制する2016
- Author(s)
  山﨑仁王、異島優、清水太郎、石田竜弘
- Organizer
  第５５回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  就実大学薬学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] Gene silencing via RNA interference (RNAi) machinery using 4'-thioDNA as an artificial template2015
- Author(s)
  Noriko Tarashima, Nozomi Kinjyo, Takamitsu Kojima, Hidenori Ando,Tatsuhiro Ishida, Noriaki Minakawa
- Organizer
  The 42nd International Symposium on Nucleic Acids Chemistry
- Place of Presentation
  I-messae hall（Himeji,Japan ）
- Year and Date
  2015-09-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04656
[Presentation] 胃がん腹膜播種モデルにおけるオキサリプラチン封入リポソーム静脈内投与による腫瘍増殖抑制効果2015
- Author(s)
  渡邉奈美、安藤英紀、石田竜弘
- Organizer
  第３１回日本DDS学会学術集会
- Place of Presentation
  京王プラザホテル（東京都新宿区）
- Year and Date
  2015-07-03
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] オキサリプラチン封入PEG修飾リポソーム製剤投与ラットの後肢皮膚組織における手足症候群様症状の評価2015
- Author(s)
  西田健太朗、柏木美咲、室木究、柴俊輔、池田理沙、石田竜弘、長澤一樹
- Organizer
  第５３回日本癌治療学会学術集会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2015-10-29
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] PEG化製剤に対するanti-PEG IgM結合特性に関する検討2015
- Author(s)
  久保幸代、本藤栄里、阿部遼、美馬優、清水太郎、石田竜弘
- Organizer
  第５４回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知テルサ（高知県高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] ヒドロキシ末端PEG修飾リポソームを用いた静注型ワクチン開発に関する基礎的検討2015
- Author(s)
  吉岡千尋、粟田瑞月、渡辺優希、清水太郎、石田竜弘
- Organizer
  第５４回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知テルサ（高知県高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26670079
[Presentation] FTY720併用によるドキシルの細胞内取り込み向上に関する検討2015
- Author(s)
  清水太郎、高橋孝典、石田竜弘
- Organizer
  第３７回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本大学薬学部（熊本県熊本市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26670079
[Presentation] P E G修飾製剤に対する免疫応答～抗P E G - I g Mの分泌誘導～2015
- Author(s)
  石田竜弘
- Organizer
  第5回薬剤学セミナー
- Place of Presentation
  熊本大学薬学部（熊本県熊本市）
- Year and Date
  2015-07-21
- Invited
- Data Source
  KAKENHI-PROJECT-26670079
[Presentation] IV 投与PEGリポソームに対するanti-PEG IgM応答への腹腔内免疫細胞の関与2015
- Author(s)
  阿部遼、清水太郎、石田竜弘
- Organizer
  日本薬剤学会第３０年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] PEG修飾タンパク質Pegasys®投与によるABC現象誘導2015
- Author(s)
  本藤栄里、美馬優、際田弘志、石田竜弘
- Organizer
  日本薬剤学会第３０年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] PEG修飾リポソームの投与経路の違いがanti-PEG IgM分泌に及ぼす影響に関する検討（第２報）2014
- Author(s)
  阿部遼、清水太郎、石田竜弘、際田弘志
- Organizer
  第２３回DDSカンファランス
- Place of Presentation
  清水テルサ（静岡県、静岡市）
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26670079
[Presentation] In vivo imaging systemによる胸腔内投与リポプレックスの動態評価2014
- Author(s)
  加藤千尋、石田竜弘、際田弘志
- Organizer
  日本薬剤学会第２９年会
- Place of Presentation
  大宮ソニックシティビル（埼玉県さいたま市）
- Year and Date
  2014-05-20
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] 脾臓辺縁帯B細胞による抗原封入PEG修飾リポソームの濾胞への輸送現象を利用した抗腫瘍免疫誘導効果2014
- Author(s)
  清水太郎、渡辺優希、美馬優、石田竜弘、際田弘志
- Organizer
  日本薬剤学会第２９年会
- Place of Presentation
  大宮ソニックシティビル（埼玉県さいたま市）
- Year and Date
  2014-05-20
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] In vivo imaging systemによる胸腔内投与リポプレックスの動態評価2014
- Author(s)
  加藤千尋、石田竜弘、際田弘志
- Organizer
  第３０回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学薬学部（東京都港区）
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] Anti-PEG immunity against PEGylated materials.2014
- Author(s)
  Ishida, T
- Organizer
  11th DDS Symposium France-Japan
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2014-10-06
- Invited
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenvironment.2014
- Author(s)
  Ishida, T.
- Organizer
  Synchrotron Radiation in Nano-medicine and Advanced Health Care (SRNAHC)
- Place of Presentation
  KONAN University (兵庫県)
- Invited
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] ナノテクノロジーを用いた薬物動態制御の可視化2014
- Author(s)
  石田竜弘
- Organizer
  高分子学会九州支部・九州有機材料研究グループ研究会
- Place of Presentation
  北九州市立大学（福岡県）
- Invited
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] リポソームからのPemetrexedの放出性が胸腔内移植腫瘍の増殖に与える影響2014
- Author(s)
  小林早紀子、Amr Abu-Lila、石田竜弘、際田弘志
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] Shotgun分析を用いたPEG修飾リポソーム結合タンパク質の網羅的解析2014
- Author(s)
  川西宗平、橋本洋佑、清水太郎、際田弘志、石田竜弘
- Organizer
  第２３回DDSカンファランス
- Place of Presentation
  清水テルサ（静岡県、静岡市）
- Year and Date
  2014-09-05
- Data Source
  KAKENHI-PROJECT-26670079
[Presentation] マウス肺癌細胞に対するFTY720とドキシルとの併用効果に関する検討2014
- Author(s)
  清水太郎、高橋孝典、石田竜弘、際田弘志
- Organizer
  第３０回日本DDS学会学術集会
- Place of Presentation
  慶應義塾大学薬学部（東京都港区）
- Year and Date
  2014-07-30
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] 転移性肝臓がんの存在がオキサリプラチン封入PEG修飾リポソームの肝移行性へ与える影響2014
- Author(s)
  藤原由佳子、中村浩之、石田竜弘、際田弘志
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本大学（熊本県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] Accelerated blood clearance phenomenon upon PEGylated protein.2013
- Author(s)
  Mima, Y., Hashimoto, Y., Shimizu, T., Ishida, T., Kiwada, H.,
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] 抗がん剤による腫瘍内微小環境変化を利用した新規DDSの開発2013
- Author(s)
  石田竜弘、際田弘志
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都府）
- Invited
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] 固形がんにおける抗がん剤封入PEG修飾リポソームとshRNA含有lipoplexによるがん治療法の確立2013
- Author(s)
  田中真生、中村浩之、森吉直人、石田竜弘、際田弘志
- Organizer
  第５２回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  松山大学（愛媛県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] 腫瘍内血管系の動的変化がPEG修飾リポソームの腫瘍内分布に及ぼす影響2013
- Author(s)
  西尾美穂、中村浩之、石田竜弘、際田弘志
- Organizer
  第22回DDSカンファランス
- Place of Presentation
  グランシップ静岡（静岡県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] Serum anti-PEG IgM concentration is a determinant factor on hepatic accumulation of PEGylated liposome in the accelerated blood clearance phenomenon.2013
- Author(s)
  Hashimoto, Y., Shimizu, T., Ishida, T., Kiwada, H.,
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] In vivo imaging systemを用いたリポソーム胸腔内投与後の体内動態の評価2013
- Author(s)
  加藤千尋、Amr Abu-Lila、石田竜弘、際田弘志
- Organizer
  第５２回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  松山大学（愛媛県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] 抗がん剤による腫瘍内微小環境変化を利用した新規DDSの開発2013
- Author(s)
  石田竜弘, 際田弘志
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ(京都府京都市)
- Year and Date
  2013-07-04
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] 脾臓辺縁体B細胞によるPEG修飾リポソームの濾胞への輸送現象を利用した特異的抗体誘導効果2013
- Author(s)
  清水太郎、渡辺優希、美馬優、橋本洋祐、石田竜弘、際田弘志
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知県産業労働センター　ウインクあいち（愛知県）
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] PEG修飾リポソームを用いた濾胞への高原送達による抗体誘導効果2013
- Author(s)
  石田竜弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-23659082
[Presentation] Potentiation of specific antibody response against antigen encapsulated in PEGylated liposomes via active transport of the liposomes from marginal zone into follicle.2013
- Author(s)
  Shimizu, T., Ishida, T., Kiwada, H.
- Organizer
  5th Asian Arden Conference
- Place of Presentation
  愛知学院大学（愛知県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] PEG修飾剤末端構造が与えるABC現象誘導への影響に関する検討2013
- Author(s)
  藤田理紗子、橋本洋佑、清水太郎、石田竜弘、際田弘志
- Organizer
  第22回DDSカンファランス
- Place of Presentation
  グランシップ静岡（静岡県）
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] siRNA搭載PEG修飾リポプレックス投与時に誘起される抗PEG IgM分泌亢進機構の解明2013
- Author(s)
  橋本洋佑、石田竜弘、際田弘志
- Organizer
  第３５回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  東京大学（東京都）
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] 腫瘍内微小環境の能動的制御に基づく腫瘍選択的デリバリーシステムの開発2013
- Author(s)
  石田竜弘
- Organizer
  日本薬学会第133年会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2013-03-30
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] 高用量PEG修飾リポソームを用いたABC現象の回避2013
- Author(s)
  美馬優、橋本洋祐、清水太郎、石田竜弘、際田弘志
- Organizer
  第29回日本DDS学会学術集会
- Place of Presentation
  京都テルサ（京都府）
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] Transport of PEGylated liposomes to follicle induced by pre-stimulation of empty liposomes: Potentiating specific antibody responses against antigen encapsulated in the liposomes.2013
- Author(s)
  Shimizu, T., Ishida, T., Kiwada, H.
- Organizer
  40th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Hawaii Convention Center (USA)
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] 高用量PEG修飾リポソームによる抗PEG IgMの分泌抑制に関する検討2013
- Author(s)
  美馬優、橋本洋佑、清水太郎、石田竜弘、際田弘志
- Organizer
  第22回DDSカンファランス
- Place of Presentation
  グランシップ静岡（静岡県）
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] siRNA搭載PEG修飾リポプレックス投与時に惹起される抗PEG IgM分泌応答機構の解明2013
- Author(s)
  橋本洋祐、清水太郎、石田竜弘、際田弘志
- Organizer
  日本薬剤学会第28年会
- Place of Presentation
  愛知県産業労働センター　ウインクあいち（愛知県）
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenvironment.2012
- Author(s)
  Ishida, T.
- Organizer
  10th DDS Symposium France-Japan
- Place of Presentation
  Grand Hotel de Bordeaux(フランス)(招待講演)
- Year and Date
  2012-10-13
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開2012
- Author(s)
  石田竜弘
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-20
- Data Source
  KAKENHI-PROJECT-23659082
[Presentation] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開2012
- Author(s)
  石田竜弘
- Organizer
  日本薬学会第126年会
- Place of Presentation
  北海道大学(北海道)(招待講演)
- Year and Date
  2012-03-30
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開2012
- Author(s)
  石田竜弘
- Organizer
  日本薬学会第132年会(招待講演)
- Place of Presentation
  北海道大学（北海道）
- Data Source
  KAKENHI-PROJECT-23659082
[Presentation] Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in murine solid tumor model.2012
- Author(s)
  Ishida, T.
- Organizer
  Oligonucleotide Delivery : Biology, Engineering and Development
- Place of Presentation
  Hernstein (オーストリア)(招待講演)
- Year and Date
  2012-10-08
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] PEG 修飾リポソームと脾臓辺縁帯 B 細胞との相互作用に関する検討2012
- Author(s)
  石田竜弘
- Organizer
  日本薬学会第132 年会
- Place of Presentation
  北海道大学(札幌市)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-23659082
[Presentation] Activation of splenic marginal zone B cell by PEGylated liposome with lower dose: triggering transport of antigen-containing second dose PEGylated liposome from marginal zone to follicle2012
- Author(s)
  Ishida, T
- Organizer
  39th Annual Meeting & Exposition of the Controlled Release Society
- Place of Presentation
  Centre des Congress de Quebec(カナダケベック)
- Year and Date
  2012-07-16
- Data Source
  KAKENHI-PROJECT-23659082
[Presentation] 腫瘍内微小環境の能動的制御による新規DDSの開発と治療への応用2012
- Author(s)
  石田竜弘
- Organizer
  創剤フォーラム第18回若手研究会
- Place of Presentation
  長井記念ホール(徳島県)(招待講演)
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-24390010
[Presentation] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenviroment2011
- Author(s)
  Ishida, T., Kiwada, H.
- Organizer
  2011 RCAA International Symposium Endogenous Ligands Modulating Anticancer Agents
- Place of Presentation
  Seoul, Korea
- Year and Date
  2011-02-11
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] PEG on nanocarriers induces anti PEG IgM production as a result of activation of immune system., Nano in Cancer : Linking Chemistry2011
- Author(s)
  Hashiguchi Y., Shimizu T., Ichihara M., Ishida T., Kiwada H.
- Organizer
  Biology and Clinical Applications in vivo
- Place of Presentation
  Miami USA, Jan.
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Anti-PEG IgM分泌誘導においてPEG修飾剤末端構造が与える影響に関する検討2011
- Author(s)
  石田竜弘
- Organizer
  第50回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  サンポートホール高松(高松市)
- Year and Date
  2011-11-13
- Data Source
  KAKENHI-PROJECT-23659082
[Presentation] 腫瘍内微小環境変化を利用した核酸デリバリー戦略2011
- Author(s)
  石田竜弘
- Organizer
  遺伝子・デリバリー研究会第11回夏期セミナー
- Place of Presentation
  三翠園ホテル(高知県高知市)
- Year and Date
  2011-08-09
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] 腫瘍内微小環境変化を利用した核酸デリバリー戦略2011
- Author(s)
  石田竜弘
- Organizer
  遺伝子・デリバリー研究会第11回夏期セミナー
- Place of Presentation
  三翠園ホテル(高知県)(招待講演)
- Year and Date
  2011-08-09
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] Biological responses against lipid membrane containing PEG2011
- Author(s)
  Ishida, T., Kiwada, H
- Organizer
  3rd International Symposium on Surface and Interface of Biomaterials (SIB2011)
- Place of Presentation
  北海道大学学術交流会館(北海道札幌市)
- Year and Date
  2011-07-14
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] Biological responses against lipid membrane containing PEG2011
- Author(s)
  Ishida, T.
- Organizer
  3rd International Symposium on Surface and Interface of Biomaterials (SIB2011)
- Place of Presentation
  北海道大学(北海道)(招待講演)
- Year and Date
  2011-07-14
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] PEG 修飾ナノキャリア投与時に惹起される免疫応答~抗PEG-IgM 分泌誘導とナノキャリアの体内動態への影響~2011
- Author(s)
  石田竜弘
- Organizer
  広島臓器移植セミナー
- Place of Presentation
  広島大学医学部(広島県広島市)
- Year and Date
  2011-08-10
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] PEG修飾ナノキャリア投与時に惹起される免疫応答～抗PEG-IgM分泌誘導とナノキャリアの体内動態への影響～2011
- Author(s)
  石田竜弘
- Organizer
  広島臓器移植セミナー
- Place of Presentation
  広島大学(広島県)(招待講演)
- Year and Date
  2011-08-10
- Data Source
  KAKENHI-PROJECT-23390012
[Presentation] A novel double modulation strategy in cancer treatment with chemothera peutic agent and siRNA : S-1 improves siRNA accumulation and then Bcl-2 knockdown by the siRNA increases chemosensitivity of 5-FU.2011
- Author(s)
  Ishida, T.
- Organizer
  NANO IN CANCER : LINKING CHEMISTRY, BIOLOGY, AND CLINICAL APPLICATIONS IN VIVO
- Place of Presentation
  Miami, USA
- Year and Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] 腫瘍内微小環境変化を利用した核酸デリバリー戦略2011
- Author(s)
  石田竜弘
- Organizer
  遺伝子・デリバリー研究会第11回夏期セミナー
- Place of Presentation
  三翠園ホテル(高知)(招待講演)
- Year and Date
  2011-08-09
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] PEG修飾ナノキャリア生体内投与後に生ずる免疫活性化(ABC現象)機構解明に関する検討2010
- Author(s)
  市原理子、石田竜弘、際田弘志
- Organizer
  第19回DDSカンファランス
- Place of Presentation
  (静岡)
- Year and Date
  2010-09-04
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Sequential treatment, pre-dose with empty PEGylated liposome (SL) and second dose antigen-encapsulating SL, promotes activation in a primary immune response.2010
- Author(s)
  Hashiguchi, Y., Shimizu, T., Ishida T., Kiwada H.
- Organizer
  International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] 腫瘍内微小環境変化を利用したsiRNAデリバリーシステムの開発2010
- Author(s)
  石田竜弘
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山市
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] Immunostimulatory properties of liposomes containing PEG.2010
- Author(s)
  Ishida, T., Kiwada, H.
- Organizer
  International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] 腫瘍内微小環境変化を利用したsiRNAデリバリーシステムの開発2010
- Author(s)
  石田竜弘、際田弘志
- Organizer
  第32回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  富山
- Year and Date
  2010-11-29
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] 核酸デリバリーにおけるABC現象2010
- Author(s)
  石田竜弘
- Organizer
  遺伝子・デリバリー研究会第10回シンポジウム
- Place of Presentation
  札幌市
- Year and Date
  2010-06-03
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] 生体内動態検討を基盤としたリポソームDDSの開発2010
- Author(s)
  石田竜弘
- Organizer
  第26回日本DDS学会
- Place of Presentation
  大阪市
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] 腫瘍へのsiRNAデリバリーシステムの開発～効果と安全性の観点から～2010
- Author(s)
  石田竜弘
- Organizer
  第47回薬剤学懇談会研究討論会
- Place of Presentation
  高山市
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] Immunostimulatory properties of liposomes containing PEG2010
- Author(s)
  Ishida, T.
- Organizer
  International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2010-08-06
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Spleen cells secret anti-PEG IgM following intravenous injection of PEGylated liposome.2010
- Author(s)
  Ichihara, M., Imoto, A., Hashiguchi, Y., Uehara, Y., Ishida T., Kiwada H.
- Organizer
  International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] 腫瘍へのsiRNAデリバリーシステムの開発～効果と安全性の観点から～2010
- Author(s)
  石田竜弘
- Organizer
  第47回薬剤学懇談会研究討論会
- Place of Presentation
  高山
- Year and Date
  2010-06-24
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] 核酸デリバリーにおけるABC現象、遺伝子・デリバリー研究会2010
- Author(s)
  石田竜弘、際田弘志
- Organizer
  第10回シンポジウム
- Place of Presentation
  (札幌)
- Year and Date
  2010-06-03
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Elucidation of ABC phenomenon caused by repeat injection of PEGylated nanocarrier.2009
- Author(s)
  Koide, H., Asai, T., Yokoyama, M., Ishida T., Kiwada H., Oku, N.
- Organizer
  4th International Liposome Society Conference. Liposome advances : Progress in Drug and Vaccine Delivery
- Place of Presentation
  London, UK
- Year and Date
  2009-12-14
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] 核酸デリバリーにおけるaccelerated blood clearance (ABC)現象2009
- Author(s)
  石田竜弘、際田弘志
- Organizer
  第25回日本DDS学会
- Place of Presentation
  (東京)
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Improvement of tumor-targeting therapy with nanocarriers by changing the tumor microenvironment2009
- Author(s)
  Ishida, T., Kiwada, H.
- Organizer
  2009 International Symposium of the Intelligent Drug Delivery System.
- Place of Presentation
  Korea
- Year and Date
  2009-04-30
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] Argonaute2標的siRNAリポプレックスを用いたがん治療戦略、学術シンポジウム4 RNAi医薬の展望. From Bench to Bedside-2009
- Author(s)
  石田竜弘、浅井知浩、奥直人、際田弘志
- Organizer
  日本薬剤学会第24年会
- Place of Presentation
  静岡
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21689002
[Presentation] 核酸デリバリーにおける accelerated blood clearance (ABC)現象2009
- Author(s)
  石田竜弘
- Organizer
  第25回日本DDS学会
- Place of Presentation
  東京都
- Year and Date
  2009-07-03
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Interaction of PEGylated liposomes with splenic marginal zone B cells may trigger production of anti-PEG IgM in the ABC phenomenon.2008
- Author(s)
  Shimizu, T., Ishida T., Kiwada H.
- Organizer
  11^<th> Liposome Research Days conference
- Place of Presentation
  Yokohama (Japan)
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] フッ素ピリミジン系抗がん剤とOxaliplatin(1-OHP)封入リポソーム併用療法に関する研究:1-OHP放出性の違いが効果と毒性に及ぼす影響2008
- Author(s)
  平百合恵、土井祐輔、石田竜弘、際田弘志
- Organizer
  第47回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  岡山
- Year and Date
  2008-11-09
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Effect of siRNA on anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon when formulated with PEGylated cationic liposome.2008
- Author(s)
  Tagami, T., Nakamura, K., Shimizu, T., Ishida T., Kiwada H.
- Organizer
  11^<th> Liposome Research Days conference
- Place of Presentation
  Yokohama (Japan)
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] ナノキャリアーを用いた抗がん剤デリバリーシステムの開発におけるinvivo イメージングの有用性2008
- Author(s)
  石田竜弘
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008
- Author(s)
  Ishida, T.
- Organizer
  11^<th> Liposome Research Days conference
- Place of Presentation
  Yokohama (Japan)
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] S-1 metronomic chemotherapyとオキサリプラチン封入ナノキャリア併用療法の開発:相乗的効果増強機構の解明に関する研究2008
- Author(s)
  土井祐輔、平百合恵、石田竜弘、際田弘志
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] PEG修飾微粒子キャリアー投与時の免疫反応2008
- Author(s)
  石田竜弘
- Organizer
  Frontier's Nanomedicine -Summer Workshop2008-
- Place of Presentation
  北海道大学大学院薬学研究院(札幌)
- Year and Date
  2008-08-05
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Unexpected immunological response against sterically stabilized, PEGylated, liposome after intravenous injection.2008
- Author(s)
  石田竜弘, 際田弘志
- Organizer
  International Symposium on "Nanotoxicology Assessment and Biomedical, Environmental Application of Fine Particles and Nanotubes" ISNT2008
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] ナノキャリアーを用いた抗がん剤デリバリーシステムの開発におけるin vivoイメージングの有用性2008
- Author(s)
  石田竜弘
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB 2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20015033
[Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008
- Author(s)
  Ishida, T.
- Organizer
  6^<th> international workshop on Drug Delivery Systems for Nanomedicine
- Place of Presentation
  Prague (the Czech Republic)
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008
- Author(s)
  Ishida, T.
- Organizer
  11^<th> Liposome Research Days conference
- Place of Presentation
  Yokohama (Japan)
- Year and Date
  2008-07-20
- Data Source
  KAKENHI-PROJECT-20015033
[Presentation] S-1を用いた Motronomic chemotherapyによって生じる腫瘍内微小環境の変化がもたらすリポソームの腫瘍内移行性の向上2008
- Author(s)
  士井祐輔、平百合恵、石田竜弘、際田弘志
- Organizer
  S-1を用いた Motronomic chemotherapyによって生じる腫瘍内微小環境の変化がもたらすリポソームの腫瘍内移行性の向上
- Place of Presentation
  静岡
- Year and Date
  2008-09-20
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Unexpected immunological response against sterically stabilized, PEGylated, liposome after intravenous injection.2008
- Author(s)
  Ishida, T.
- Organizer
  International Symposium on“Nanotoxicology Assessment and Biomedical, Environmental Application of Fine Particles and Nanotubes"(ISNT2008)
- Place of Presentation
  Sapporo
- Year and Date
  2008-06-17
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Accelerated blood clearance (ABC) phenomenon on PEGylated nanocarrier : Unexpected immune-reaction against PEGylated liposome.2008
- Author(s)
  Shimizu, T., Ishida T., Kiwada H.
- Organizer
  International Symposium on "Nanotoxicology Assessment and Biomedical, Environmental Application of Fine Particles and Nanotubes" (ISNT2008)
- Place of Presentation
  Sapporo, Japan
- Data Source
  KAKENHI-PROJECT-20390013
[Presentation] Improvement of tumortargeting therapy with nanocarrier by changing the tumor microenvironment2008
- Author(s)
  Ishida,T., Kiwada, H.,
- Organizer
  llth Liposome Research Days conference
- Place of Presentation
  Yokohama(Japan)
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008
- Author(s)
  Ishida, T.
- Organizer
  6^<th> international workshop on Drug Delivery Systems for Nanomedicine
- Place of Presentation
  Prague (the Czech Republic)
- Year and Date
  2008-10-05
- Data Source
  KAKENHI-PROJECT-20015033
[Presentation] ナノキャリアーを用いた抗がん剤デリバリーシステムの開発におけるin vivoイメージングの有用性2008
- Author(s)
  石田竜弘
- Organizer
  第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB2008
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment.2008
- Author(s)
  Ishida, T., Kiwada, H.,
- Organizer
  6th international workshop on Drug Delivery Systems for Nanomedicine,
- Place of Presentation
  Prague (the Czech Republicl)
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Anti-MT1-MMPimmunoliposomeの血管内皮細胞(HUVEC)における内在化経路の検討2007
- Author(s)
  下田かおり、跡部一孝、石田竜弘、橋本浩一、小林英夫、安田純子、青木隆則、小幡賢一、菊池寛、秋田英万、浅井知浩、原島秀吉、奥直人、際田弘志
- Organizer
  Anti-MT1-MMPimmunoliposomeの血管内皮細胞(HUVEC)における内在化経路の検討
- Place of Presentation
  熊本
- Year and Date
  2007-06-14
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] 肺転移性melanoma細胞に対するシクロスファミドを用いたlow-dose metronomic chemotherapyにおけるドキソルビシン封入リポソームの併用効果の検討2007
- Author(s)
  萩歩美、白髪恵美、石田竜弘、際田弘志
- Organizer
  第23回日本DDS学会
- Place of Presentation
  熊本
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] シクロフォスファミドを用いた low dose metronomic chemotherapy におけるドキソルビシン封入リポソームの併用効果および毒性の検討2007
- Author(s)
  白髪恵美、石田竜弘、際田弘志
- Organizer
  第16回DDSカンファランス
- Place of Presentation
  静岡
- Year and Date
  2007-07-14
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] シクロフォスファミドを用いたlow dose metronomic chemotherapy およびドキソルビシン封入リポソーム併用による抗腫瘍効果の検討2007
- Author(s)
  白髪恵美、石田竜弘、際田弘志
- Organizer
  日本薬剤学会第22年会
- Place of Presentation
  大宮
- Year and Date
  2007-05-23
- Data Source
  KAKENHI-PROJECT-19790128
[Presentation] Intelligent RNA expressing device (iRed) を利用した核酸創薬の新手法
- Author(s)
  田良島典子，小島孝光，金城望，古川和寛、安藤英紀，石田竜弘，南川典昭
- Organizer
  第３２回メディシナルケミストリーシンポジウム
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2014-11-26 – 2014-11-28
- Data Source
  KAKENHI-PROJECT-24390027
[Presentation] Intelligent RNA expression device (iRed) を利用した新規遺伝子発現抑制法の開発
- Author(s)
  田良島典子, 小島孝允, 金城望, 古川和寛, 安藤　英紀, 石田竜弘, 南川典昭
- Organizer
  第９５回日本化学会
- Place of Presentation
  日本大学　船橋キャンパス（千葉県船橋市）
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-24390027

1. KIWADA Hiroshi (50120184)

# of Collaborated Projects: 7 results

# of Collaborated Products: 75 results
2. 清水太郎 (30749388)

# of Collaborated Projects: 6 results

# of Collaborated Products: 18 results
3. ISHIMA Yu (00457590)

# of Collaborated Projects: 5 results

# of Collaborated Products: 33 results
4. 安藤英紀 (00735524)

# of Collaborated Projects: 5 results

# of Collaborated Products: 15 results
5. MINAKAWA Noriaki (40209820)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
6. 小田切優樹 (80120145)

# of Collaborated Projects: 2 results

# of Collaborated Products: 22 results
7. KATAOKA Masaroshi (20224438)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHINOHARA Yasuo (60226157)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. MORI Shuji (50220009)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐塚泰之 (90162403)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 山崎尚志 (20271083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 鵜川真実 (50735511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 阿部洋 (80415067)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中村嘉利 (20172455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 森脇真希 (10444192)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 浅田元子 (10580954)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中崎清彦 (70180263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岡田直人 (30623269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 田島健次 (00271643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
20. 佐藤敏文 (80291235)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 磯野拓也 (70740075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 甲野裕之 (70455096)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 藤田彩華 (90782011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 奥平桂一郎 (10425671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
25. 田中将史 (40411904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 小出裕之 (60729177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. EMAM SHERIF

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. WATANABE Hiroshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
29. MARUYAMA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
30. KOGA Tomoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. FUJIWARA Yukio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. WATANABE Takehisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 関貴弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 香月博志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 森岡弘志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 田良島典子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
38. 古川和寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 竹屋元裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 佐々木裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
41. 國安明彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
42. 小橋川敬博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ishida Tatsuhiro 石田 竜弘

ISHIDA Tatsuhiro 石田 竜弘

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PEG修飾エクソソームを用いた脾臓辺縁体B細胞標的型コロナウイルスワクチンの開発Host Researcher

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Enhanced absorption drug delivery system by ionic liquidPrincipal Investigator

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PEG修飾タンパクによるアナフィラキシー誘導機構の解明とその制御に関する研究Principal Investigator

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Development of transdermal drug delivery system by ionic liquidPrincipal Investigator

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Mannupulating inate immunity for new vaccine against cancer(Fostering Joint International Research)Principal Investigator

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Development of nover antigen delivery system for tumor therapyPrincipal Investigator

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Study of immunological response to nucleic acid delivery systemPrincipal Investigator

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Ishida Tatsuhiro 石田竜弘

ISHIDA Tatsuhiro 石田竜弘