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Ishida Tatsuhiro  石田 竜弘

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ISHIDA Tatsuhiro  石田 竜弘

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Researcher Number 50325271
Other IDs
Affiliation (Current) 2022: 徳島大学, 大学院医歯薬学研究部(薬学域), 教授
Affiliation (based on the past Project Information) *help 2018 – 2022: 徳島大学, 大学院医歯薬学研究部(薬学域), 教授
2015 – 2017: 徳島大学, 大学院医歯薬学研究部(薬学系), 教授
2015: 徳島大学, 大学院医歯薬学研究部, 教授
2014: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 教授
2013 – 2014: 徳島大学, ヘルスバイオサイエンス研究部, 教授 … More
2013: 徳島大学, ヘルスバイオサイエンス研究部, 教授(Professor)
2013: 徳島大学, 大学院・へルスバイオサイエンス研究部, 教授
2011 – 2012: 徳島大学, ヘルスバイオサイエンス研究部, 准教授
2007 – 2012: The University of Tokushima, 大学院・ヘルスバイオサイエンス研究部, 准教授
2006 – 2007: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授
2005 – 2006: 徳島大学, 大学院ヘルスバイオサイエンス研究部, 助教授
2004: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教授
2003: 徳島大学, 薬学部, 助教授
2002: 徳島大学, 薬学部, 講師 Less
Review Section/Research Field
Principal Investigator
Physical pharmacy / Medical pharmacy / Medium-sized Section 90:Biomedical engineering and related fields / 医薬分子機能学
Except Principal Investigator
Basic Section 47060:Clinical pharmacy-related / Biological Sciences / Physical pharmacy / Drug development chemistry / Science and Engineering / Medium-sized Section 64:Environmental conservation measure and related fields / Basic Section 28030:Nanomaterials-related / Basic Section 59040:Nutrition science and health science-related / Basic Section 90110:Biomedical engineering-related
Keywords
Principal Investigator
リポソーム / DDS / がん治療 / ワクチン / 抗がん剤 / がん新生血管 / ナノキャリア / アジュバント / PEG / イオン液体 … More / ドラッグデリバリーシステム / 癌化学療法 / 多剤耐性 / 遺伝子治療 / 遺伝子デリバリー / 癌 / 癌治療 / 癌新生血管 / がん / モデル動物 / 体内動態制御 / 腫瘍 / EPR効果 / 腫瘍内微小環境 / メトロノミック・ケモセラピー / 抗がく剤 / 薬物動態 / 代謝学 / 抗原デリバリー / ポリエチレングリコール / 免疫反応 / ドラッグデリバリー / がん微小環境 / 血液型不適合肝移植 / 抗血液型抗体 / PEG修飾リポソーム / DDS / 移植拒絶 / 免疫制御 / PEG修飾リポソーム / TI抗原 / 核酸 / 免疫 / Anti-PEG IgM / 核酸デリバリー / 自然免疫活性化 / 経皮吸収 / ペプチド / PEG修飾製剤 / 抗PEG抗体 / infusion reaction / CARPA / 経口投与 / 腸管吸収 … More
Except Principal Investigator
リポソーム / DDS / RNAi創薬 / アルブミン / ドラッグデリバリーシステム / 膜タンパク質 / 試験管内タンパク質合成 / コートペプチド / 細胞機能模倣 / 再構成 / 高次構造 / フォールディング / 抗体 / プロテインA / 細胞機能の模倣 / マイクロチップ電気泳動 / ナノバイオデバイス / 合成ペプチド / マイクロファブリケーション / がん / 新生血管 / モデル動物 / 体内動態制御 / がん治療 / 抗がん剤 / 腫瘍内微小環境 / メトロノミック・ケモセラピー / ナノキャリア / 免疫系 / 抗PEG-IgM / B細胞 / ナノトキシコロジー / ポリエチレングリコール / 免疫反応 / DDS / PEG / ABC現象 / Anti-PEG IgM / 免疫活性化 / PEG / 4'-チオDNA / PCR / 非天然塩基対 / クリックケミストリー / 免疫応答 / 核酸創薬 / DNAデバイス / 化学合成 / バイオマス / 膵臓がん / ナノ粒子 / ナノセルロース / ネットワーク構造 / 腹膜播種 / 徐放 / 毒性低減 / 酸素移動容量係数 / 表面改質 / シランカップリング / グラフト化 / 開環重合 / 腹腔内滞留性向上 / 副作用低減 / 薬剤送達 / ボトムアップ / バイオリファイナリー / セルロース合成菌 / 高密度リポ蛋白質 / 動脈硬化 / 高密度リポタンパク質 / アポリポタンパク質 / アポリポタンタンパク質 / 脾臓免疫 / 抗体誘導 / エキソソーム / 膜タンパク / アルブミン受容体 / アクティブターゲティング / ワクチン / COVID-19 / コロナワクチン Less
  • Research Projects

    (27 results)
  • Research Products

    (223 results)
  • Co-Researchers

    (42 People)
  •  高活性抗体の誘導を実現する抗原発現エキソソームの脾臓免疫技術基盤の構築

    • Principal Investigator
      安藤 英紀
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      The University of Tokushima
  •  Development of albumin DDS carrier based on an understanding of the endogenous albumin transport system

    • Principal Investigator
      異島 優
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      The University of Tokushima
  •  短時間高活性水熱前処理を用いた利益創出・エコ型バイオマス全成分有効利用法の開発

    • Principal Investigator
      中村 嘉利
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 64:Environmental conservation measure and related fields
    • Research Institution
      The University of Tokushima
  •  動脈硬化治療法の確立に向けたHDLリモデリングの分子基盤の解明とその応用

    • Principal Investigator
      奥平 桂一郎
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Osaka Medical and Pharmaceutical University
      Osaka University of Pharmaceutical Sciences
  •  PEG修飾エクソソームを用いた脾臓辺縁体B細胞標的型コロナウイルスワクチンの開発Host Researcher

    • Host Researcher
      石田 竜弘
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      The University of Tokushima
  •  Enhanced absorption drug delivery system by ionic liquidPrincipal Investigator

    • Principal Investigator
      石田 竜弘
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokushima
  •  PEG修飾タンパクによるアナフィラキシー誘導機構の解明とその制御に関する研究Principal Investigator

    • Principal Investigator
      石田 竜弘
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokushima
  •  Efficient anticancer drug delivery using a network structure of nanocellulose with a super high aspect ratio

    • Principal Investigator
      田島 健次
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 28030:Nanomaterials-related
    • Research Institution
      Hokkaido University
  •  Development of transdermal drug delivery system by ionic liquidPrincipal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      The University of Tokushima
  •  Development of novel multifunctional nanoparticles based on uptake mechanism of endogenous albumin by pancreatic cancer cells

    • Principal Investigator
      ISHIMA Yu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47060:Clinical pharmacy-related
    • Research Institution
      The University of Tokushima
  •  Mannupulating inate immunity for new vaccine against cancer(Fostering Joint International Research)Principal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  Development of nover antigen delivery system for tumor therapyPrincipal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  Study of immunological response to nucleic acid delivery systemPrincipal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  Investigation of practical anticancer strategy based on chemically synthesized iRed/iPed

    • Principal Investigator
      MINAKAWA Noriaki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      The University of Tokushima
  •  Immunosuppression of anticancer agents containing PEGylated liposomes for liver transplantation.Principal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokushima
  •  Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenvironment.Principal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  Development of a novel RNAi medicine based on shRNA expression mini-plasmid

    • Principal Investigator
      MINAKAWA Noriaki
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      The University of Tokushima
  •  Anti-PEG Immunity upon nucleic acid delivery

    • Principal Investigator
      KIWADA Hiroshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  Development of novel vaccine system with nanocarrierPrincipal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokushima
  •  Evaluation on EPR effect and active control of EPR effect for achieving efficient tumor accumulation of nanocarrier delivery systemPrincipal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  腫瘍内微小環境変化を利用した新規DDSの開発

    • Principal Investigator
      際田 弘志
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Study for Interaction of Biological Milieu with Nano-drug Carrier system

    • Principal Investigator
      KIWADA Hiroshi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Physical pharmacy
    • Research Institution
      The University of Tokushima
  •  Application of liposomal anticancer drug for tumor dormant therapyPrincipal Investigator

    • Principal Investigator
      ISHIDA Tatsuhiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokushima
  •  がん新生血管を標的とした機能性リポソームによる革新的治療法の開発

    • Principal Investigator
      KIWADA Hiroshi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The University of Tokushima
  •  Characterization of cell-free protein synthesis system and theapplication for the synthesis of cell membrane protein

    • Principal Investigator
      KATAOKA Masaroshi
    • Project Period (FY)
      2005 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Science and Engineering
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
      The University of Tokushima
  •  ナノベクター標的化による新生血管選択的遺伝子発現法の開発とそのがん治療への応用Principal Investigator

    • Principal Investigator
      石田 竜弘
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Medical pharmacy
    • Research Institution
      The University of Tokushima
  •  癌化学療法における多剤耐性の克服を目指した機能性リポソームの研究開発Principal Investigator

    • Principal Investigator
      石田 竜弘
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      医薬分子機能学
    • Research Institution
      The University of Tokushima

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent

  • [Book] セルロースナノファイバー製造・利用の最新動向2019

    • Author(s)
      田島健次、小瀬亮太、石田竜弘、松島得雄
    • Total Pages
      10
    • Publisher
      シエムシー出版
    • ISBN
      9784781314044
    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Book] Cationic liposomes and tumour vasculature targeting : a therapeutic approach that has potential for solid tumours2011

    • Author(s)
      Abu Lila A. S., Ishida T., Kiwada, H.
    • Publisher
      i-Smithers-Creative Publishing Solutions
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Book] Breaking the barriers to tumor-targeting via nanocarrier-based drug delivery to the tumor microenvironment2010

    • Author(s)
      Doi, Y., Ishida, T., Kiwada, H.
    • Publisher
      Nova Science Publishers
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Book] Unexpected reactions by in vivo application of PEGylated liposomes. "(Safety of Nanoparticles : From Manufacturing to Clinical Applications (A volume in the Nanostructure Science and Technology series))(T.J.Webster (Ed.)), Chapter 6, p111-1302009

    • Author(s)
      Ishida, T., Kiwada, H.
    • Publisher
      Springer Science + Business Media, New York, USA
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Therapeutic efficacy of a paclitaxel-loaded nanofibrillated bacterial cellulose (PTX/NFBC) formulation in a peritoneally disseminated gastric cancer xenograft model2021

    • Author(s)
      Akagi Shunsuke、Ando Hidenori、Fujita Kenji、Shimizu Taro、Ishima Yu、Tajima Kenji、Matsushima Tokuo、Kusano Takatomo、Ishida Tatsuhiro
    • Journal Title

      International Journal of Biological Macromolecules

      Volume: 174 Pages: 494-501

    • DOI

      10.1016/j.ijbiomac.2021.01.201

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Journal Article] Cell-penetrating mechanism of intracellular targeting albumin: Contribution of macropinocytosis induction and endosomal escape.2020

    • Author(s)
      Ichimizu Shota、Watanabe Hiroshi、Maeda Hitoshi、Hamasaki Keisuke、Ikegami Komei、Chuang Victor Tuan Giam、Kinoshita Ryo、Nishida Kento、Shimizu Taro、Ishima Yu、Ishida Tatsuhiro、Seki Takahiro、Katsuki Hiroshi、Futaki Shiroh、Otagiri Masaki、Maruyama Toru
    • Journal Title

      J Control Release.

      Volume: 304 Pages: 156-163

    • DOI

      10.1016/j.jconrel.2019.05.015

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-19K07123, KAKENHI-PROJECT-16H04673, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604
  • [Journal Article] Albumin domain mutants with enhanced Aβ binding capacity identified by phage display analysis for application in various peripheral Aβ elimination approaches of Alzheimer's disease treatment2020

    • Author(s)
      Ishima Yu、Mimono Ai、Tuan Giam Chuang Victor、Fukuda Tetsuya、Kusumoto Kohshi、Okuhira Keiichiro、Suwa Yoshiaki、Watanabe Hiroshi、Ishida Tatsuhiro、Morioka Hiroshi、Maruyama Toru、Otagiri Masaki
    • Journal Title

      IUBMB Life.

      Volume: 72 Pages: 641-651

    • DOI

      10.1002/iub.2203

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-20H04124
  • [Journal Article] Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice2020

    • Author(s)
      Elsadek Nehal E.、Abu Lila Amr S.、Emam Sherif E.、Shimizu Taro、Takata Haruka、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
    • Journal Title

      European Journal of Pharmaceutics and Biopharmaceutics

      Volume: 152 Pages: 56-62

    • DOI

      10.1016/j.ejpb.2020.04.026

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0279
  • [Journal Article] Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon.2020

    • Author(s)
      El Sayed, M.M., Takata, H., Shimizu, T., Kawaguchi, Y., Abu Lila, A.S., Elsadek, N.E., Alaaeldin, E., Ishima, Y., Ando, H., Kamal, A., Sarhan, H.A., Ishida, T.
    • Journal Title

      J. Conrol. Release

      Volume: 323 Pages: 102-109

    • DOI

      10.1016/j.jconrel.2020.04.011

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0279
  • [Journal Article] S-Nitrosated alpha-1-acid glycoprotein exhibits antibacterial activity against multidrug-resistant bacteria strains and synergistically enhances the effect of antibiotics2019

    • Author(s)
      Ishima Yu、Watanabe Kaori、Chuang Victor T. G.、Takeda Iyo、Kuroda Teruo、Ogawa Wakano、Watanabe Hiroshi、Iwao Yasunori、Ishida Tatsuhiro、Otagiri Masaki、Maruyama Toru
    • Journal Title

      FASEB Bioadv

      Volume: 1 Pages: 137-150

    • DOI

      10.1096/fba.1018

    • NAID

      120007153321

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604
  • [Journal Article] ナノフィブリル化バクテリアセルロース(Fibnano)を用いた腹腔内投与型がん治療製剤への応用2019

    • Author(s)
      安藤英紀、田島健次、松島得雄、石田竜弘
    • Journal Title

      Cellulose Communications

      Volume: 26 Pages: 173-177

    • NAID

      40022090343

    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Journal Article] Distribution of polysulfide in human biological fluids and their association with amylase and sperm activities2019

    • Author(s)
      Ikeda Mayumi、Ishima Yu、Chuang Victor T. G.、Sakai Maki、Osafune Hiroki、Ando Hidenori、Shimizu Taro、Okuhira Keiichiro、Watanabe Hiroshi、Maruyama Toru、Otagiri Masaki、Akaike Takaaki、Ishida Tatsuhiro
    • Journal Title

      Molecules

      Volume: 24 Pages: 1689-1689

    • DOI

      10.3390/molecules24091689

    • NAID

      120006995454

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-16K08236, KAKENHI-PROJECT-18H05277
  • [Journal Article] フルーツ由来新奇酢酸菌によるナノセルロースの合成とその応用2019

    • Author(s)
      田島健次、小瀬亮太、松島得雄、石田竜弘、安藤英紀
    • Journal Title

      日本醸造協会誌

      Volume: 114 Pages: 540-549

    • NAID

      40022026601

    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Journal Article] Involvement of complement activation in the pulmonary vasoactivity of polystyrene nanoparticles in pigs: Unique surface properties underlying alternative pathway activation and instant opsonization.2018

    • Author(s)
      Meszaros, T., Kozma, G., Shimizu, T., Miyahara, K., Turjeman, K., Ishida, T., Barenholz, Y., Urbanics, R., Szebeni, J.
    • Journal Title

      Int. J. Nanomed.

      Volume: 13 Pages: 6345-6357

    • DOI

      10.2147/ijn.s161369

    • NAID

      120006956857

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0310
  • [Journal Article] Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens2018

    • Author(s)
      8.Ando, H., Abu Lila, A.S., Kawanishi, M., Shimizu, T., Okuhira, K., Ishima, Y., Ishida, T.
    • Journal Title

      Journal of Controlled Release

      Volume: 270 Pages: 114-119

    • DOI

      10.1016/j.jconrel.2017.12.002

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639, KAKENHI-PROJECT-16K15108, KAKENHI-PROJECT-16K08236
  • [Journal Article] A novel S-sulfhydrated human serum albumin preparation suppresses melanin synthesis.2018

    • Author(s)
      Ikeda M, Ishima Y, Kinoshita R, Chuang VTG, Tasaka N, Matsuo N, Watanabe H, Shimizu T, Ishida T, Otagiri M, Maruyama T,
    • Journal Title

      Redox Biol.

      Volume: 14 Pages: 354-360

    • DOI

      10.1016/j.redox.2017.10.007

    • NAID

      120007029979

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
  • [Journal Article] Thioredoxin-albumin fusion protein prevents copper enhanced zinc-induced neurotoxicity via its antioxidative activity2018

    • Author(s)
      Tanaka KI, Shimoda M, Chuang VTG, Nishida K, Kawahara M, Ishida T, Otagiri M, Maruyama T, Ishima Y.
    • Journal Title

      International Journal of Pharmaceutics

      Volume: 535 Pages: 140-147

    • DOI

      10.1016/j.ijpharm.2017.11.012

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-18H02587
  • [Journal Article] Development of kupffer cell targeting type-Ⅰ interferon for the treatment of hepatitis via Inducing anti-inflammatory and immunomodulatory actions2018

    • Author(s)
      Minayoshi Y, Maeda H, Yanagisawa H, Hamasaki K, Mizuta Y, Nishida K, Kinoshita R, Enoki Y, Imafuku T, Chuang VTG, Koga T, Fujiwara Y, Takeya M, Sonoda K, Wakayama T, Taguchi K, Ishima Y, Ishida T, Iwakiri Y, Tanaka M, Sasaki Y, Watanabe H, Otagiri M, Maruyama T.
    • Journal Title

      Drug Deliv.

      Volume: 25 Pages: 1055-1065

    • DOI

      10.1080/10717544.2018.1464083

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08664, KAKENHI-PROJECT-17K15511, KAKENHI-PROJECT-17H04060, KAKENHI-PROJECT-16K09247, KAKENHI-PROJECT-18H02587, KAKENHI-PROJECT-18H02798
  • [Journal Article] Design and tuning of a cell-penetrating albumin derivative as a versatile nanovehicle for intracellular drug delivery.2018

    • Author(s)
      Ichimizu Shota、Watanabe Hiroshi、Maeda Hitoshi、Hamasaki Keisuke、Nakamura Yuka、Chuang Victor Tuan Giam、Kinoshita Ryo、Nishida Kento、Tanaka Ryota、Enoki Yuki、Ishima Yu、Kuniyasu Akihiko、Kobashigawa Yoshihiro、Morioka Hiroshi、Futaki Shiro、Otagiri Masaki、Maruyama Toru
    • Journal Title

      J. Control. Release.

      Volume: 277 Pages: 23-34

    • DOI

      10.1016/j.jconrel.2018.02.037

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08383, KAKENHI-PROJECT-15K14983, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-17H04105, KAKENHI-PROJECT-18H02587
  • [Journal Article] Dual Therapeutic Effects of an Albumin-Based Nitric Oxide Donor on 2 Experimental Models of Chronic Kidney Disease.2018

    • Author(s)
      Oshiro S, Ishima Y, Maeda H, Honda N, Bi J, Kinoshita R, Ikeda M, Iwao Y, Imafuku T, Nishida K, Miyamura S, Watanabe H, Otagiri M, Maruyama T
    • Journal Title

      Journal of Pharmaceutical Sciences

      Volume: 107 Pages: 140-147

    • DOI

      10.1016/j.xphs.2017.10.023

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04758, KAKENHI-PROJECT-15K08076, KAKENHI-PROJECT-16K15320, KAKENHI-PROJECT-18H02604, KAKENHI-PROJECT-18J10935, KAKENHI-PROJECT-18H02587
  • [Journal Article] Intratumoral Visualization of Oxaliplatin within a Liposomal Formulation Using X-ray Fluorescence Spectrometry2018

    • Author(s)
      5.Ando, H., Abu Lila, A.S., Tanaka, M., Doi, Y., Terada, Y., Yagi, N., Shimizu, T., Okuhira, K., Ishima, Y., Ishida, T.,
    • Journal Title

      Molecular Pharmaceutics

      Volume: 15 Pages: 403-409

    • DOI

      10.1021/acs.molpharmaceut.7b00762

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639, KAKENHI-PROJECT-16K08236
  • [Journal Article] Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity.2017

    • Author(s)
      Mima, Y., Abu Lila, A.S., Shimizu, T., Ukawa, M., Ando, H., Kurata, Y., Ishida, T.
    • Journal Title

      J. Control Release

      Volume: 250 Pages: 20-26

    • DOI

      10.1016/j.jconrel.2017.01.040

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Journal Article] Metronomic S-1 dosing and thymidylate synthase silencing have synergistic antitumor efficacy in a colorectal cancer xenograft model.2017

    • Author(s)
      17.Abu Lila, A.S., Moriyoshi, N., Fukushima, M., Huang, C., Wada, H., Ishida, T.
    • Journal Title

      Cancer Letters

      Volume: 400 Pages: 223-231

    • DOI

      10.1016/j.canlet.2016.11.005

    • NAID

      120006894605

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Journal Article] Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.2017

    • Author(s)
      11.Shimizu, T., Abu Lila, A.S., Nishio, M., Doi, Y., Ando, H., Ukawa, M., Ishima, Y., Ishida, T.
    • Journal Title

      Cancer Sci.

      Volume: 108 Pages: 1864-1869

    • DOI

      10.1111/cas.13305

    • NAID

      120006535002

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Journal Article] Co-administration of liposomal l-OHP and PEGylated TS shRNA-lipoplex: A novel approach to enhance anti-tumor efficacy and reduce the immunogenic response to RNAi molecules.2017

    • Author(s)
      12.Alaaeldin, E., Abu Lila, A.S., Ando, H., Fukushima, M., Huang, C., Wada, H., Sarhan, H.A., Khaled, K.A., Ishida, T.
    • Journal Title

      J. Control Release

      Volume: 255 Pages: 210-217

    • DOI

      10.1016/j.jconrel.2017.04.040

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Journal Article] Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model.2016

    • Author(s)
      Abu Lila, A.S., Kato, C., Fukushima, M., Huang, C., Wada, H., Ishida, T.
    • Journal Title

      Int. J. Oncol.

      Volume: 48 Pages: 1399-1407

    • DOI

      10.3892/ijo.2016.3367

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Journal Article] Gene silencing using 4'-thioDNA as an artificial template to synthesize short-hairpin RNA without inducing a detectable innate immune response2016

    • Author(s)
      Noriko Tarashima, Hidenori Ando,Takamitsu Kojima,Nozomi Kinjo,Yosuke Hashimoto,Kazuhiro Furukawa,Tatsuhiro Ishida, Noriaki Minakawa
    • Journal Title

      Mol. Ther. Nucl. Acids

      Volume: 5

    • DOI

      10.1038/mtna.2015.48

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04656, KAKENHI-PROJECT-15H06446
  • [Journal Article] Anti-PEG IgM is a major contributor to the accelerated blood clearance of polyethylene glycol-conjugated protein.2015

    • Author(s)
      Mima, Y., Hashimoto, Y., Shimizu, T., Kiwada, H., Ishida, T.
    • Journal Title

      Mol. Pharmaceutics

      Volume: 12 Pages: 2429-2435

    • DOI

      10.1021/acs.molpharmaceut.5b00144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Journal Article] Synthesis of DNA fragments containing 2’-deoxy-4’-selenonucleoside units using DNA polymerases: comparison of dNTPs with O, S and Se at the 4’-position in replication.2015

    • Author(s)
      Noriko Tarashima, Tatsuya Sumitomo, Hidenori Ando, Kazuhiro Furukawa, Tatsuhiro Ishida and Noriaki Minakawa*
    • Journal Title

      Org. Biomol. Chem.

      Volume: 13 Pages: 6949-6952

    • DOI

      10.1039/c5ob00941c

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04656, KAKENHI-PROJECT-15H06446, KAKENHI-PROJECT-26630432
  • [Journal Article] Comprehensive analysis of PEGylated liposome-asscociated proteins relating to the accelerated blood clearance phenomenon by combination with shotgun analysis and conventional methods.2015

    • Author(s)
      Kawanishi, M., Hashimoto, Y., Shimizu, T., Sagawa, I., Ishida, T., Kiwada, H.
    • Journal Title

      Biotech. Appl. Biochem.

      Volume: 62 Pages: 547-555

    • DOI

      10.1002/bab.1291

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Journal Article] Sequential treatment of oxaliplatin-containing PEGylated liposome together with S-1 improves intratumor distribution of subsequent doses of oxaliplatin-containing PEGylated liposome.2014

    • Author(s)
      Nakamura, H., Doi, Y., Abu Lila, A.S., Nagao, A., Ishida, T., Kiwada, H
    • Journal Title

      Eur. J. Pharm. Biopharm.

      Volume: 87 Pages: 142-151

    • DOI

      10.1016/j.ejpb.2013.12.007

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Journal Article] Application of polyglycerol-coating to pDNA lipoplex for the evasion of the accelerated blood clearance (ABC) phenomenon in nucleic acid delivery.2014

    • Author(s)
      Abu Lila, A.S., Uehara, Y., Ishida, T., Kiwada, H
    • Journal Title

      J. Pharm. Sci.

      Volume: 103 Pages: 557-566

    • DOI

      10.1002/jps.23823

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Influence of dose and animal species on accelerated blood clearance of PEGylated liposomal doxorubicin.2014

    • Author(s)
      Suzuki, T., Ichihara, M., Hyodo, K., Yamamoto, E., Ishida, T., Kiwada, H., Kikuchi, H., Ishihara, H.
    • Journal Title

      Int. J. Pharm

      Volume: 476 Pages: 205-212

    • DOI

      10.1016/j.ijpharm.2014.09.047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Journal Article] B cell-intrinsic toll-like receptor 7 is responsible for the enhanced anti-PEG IgM production following injection of siRNA-containing PEGylated lipoplex in mice2014

    • Author(s)
      Hashimoto, Y., Abu Lila A., Shimizu, T., Ishida, T., Kiwada, H
    • Journal Title

      J. Control. Release

      Volume: 184C Pages: 1-8

    • DOI

      10.1016/j.jconrel.2014.04.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Generation, characterization and in vivo biological activity of two distinct monoclonal anti-PEG IgMs.2014

    • Author(s)
      Hashimoto Y., Shimizu T., Mima Y., Abu Lila A., Ishida T., Kiwada H
    • Journal Title

      Toxicol. Appl. Pharmacol.

      Volume: 277 Pages: 30-38

    • DOI

      10.1016/j.taap.2014.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage.2013

    • Author(s)
      Abu Lila, A.S., Kiwada, H., Ishida, T.
    • Journal Title

      J. Control. Release

      Volume: 172 Pages: 38-47

    • DOI

      10.1016/j.jconrel.2013.07.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] The co-delivery of oxaliplatin abrogates the immunogenic response to PEGylated siRNA-lipoplex.2013

    • Author(s)
      Alaaeldin, E.,, Abu Lila, A.S., Moriyoshi, N., Sarahan, H.A., Ishida, T., Khaled A. Khale, Kiwada, H
    • Journal Title

      Pharm. Res.

      Volume: 30 Pages: 2344-2354

    • DOI

      10.1007/s11095-013-1078-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Abrogation of the accelerated blood clearance phenomenon by SOXL regimen : Promise for clinical application2013

    • Author(s)
      Nagao, A., Abu Lila, A.S., Ishida, T, Kiwada, H
    • Journal Title

      Int. J. Pharm

      Volume: 441 Pages: 395-401

    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Ex-vivo/in-vitro anti-polyethylene Glycol (PEG) IgM production from murine splenic B cells stimulated by PEGylated liposome.2013

    • Author(s)
      Abu Lila, A.S., Ichihara, M., Shimizu, T., Ishida, T., Kiwada, H.
    • Journal Title

      Biol. Pharm. Bull.

      Volume: 36 Pages: 1842-1848

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Transport of PEGylated liposomes from the splenic marginal zone to the follicle in the induction phase of the accelerated blood clearance phenomenon2013

    • Author(s)
      Shimizu T
    • Journal Title

      Immunobiol

      Volume: 218 Pages: 725-732

    • DOI

      10.1016/j.imbio.2012.08.274

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012, KAKENHI-PROJECT-23659082
  • [Journal Article] Use of polyglycerol (PG), instead of polyethylene glycol (PEG), prevents induction of the accelerated blood clearance phenomenon against long-circulating liposomes upon repeated administration.2013

    • Author(s)
      Abu Lila, A.S., Nawata, K., Shimizu, T., Ishida, T., Kiwada, H.
    • Journal Title

      Int. J. Pharm.

      Volume: 456 Pages: 235-242

    • DOI

      10.1016/j.ijpharm.2013.07.059

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Accelerated blood clearance of PEGylated liposomes containing doxorubicin upon repeated administration to dogs.2012

    • Author(s)
      Suzuki, T., Ichihara, M., Hyodo, K., Yamamoto, E., Ishida, T., Kiwada, H., Ishihara, H., Kikuchi, H
    • Journal Title

      Int. J. Pharm.

      Volume: 436 Pages: 636-643

    • DOI

      10.1016/j.ijpharm.2012.07.049

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in a murine solid tumor model2012

    • Author(s)
      Tagami, T., Abu Lila, A. S., Matsunaga, M., Moriyoshi, N., Nakamura, H., Nakamura, K., Suzuki, T., Doi, Y., Ishida, T., Kiwada, H.
    • Journal Title

      Drug Deliv. Transl. Res.

      Volume: 2 Pages: 77-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Combination therapy with metronomic S-1 dosing and oxaliplatin-containing PEG-coated cationic liposomes in a murine colorectal tumor model : Synergy or antagonism?2012

    • Author(s)
      Abu Lila, A. S., Okada, T., Doi, Y., Ichihara, M., Ishida, T., Kiwada, H.
    • Journal Title

      Int. J. Pharm.

      Volume: 426 Pages: 263-270

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Anti-PEG IgM response against PEGylated liposomes in mice and rats.2011

    • Author(s)
      Ichihara M., Shimizu T., Imoto A., Hashiguchi Y., Uehara Y., Ishida T, Kiwada H.
    • Journal Title

      Pharmaceutics in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA2011

    • Author(s)
      Tagami T., Uehara Y., Moriyoshi N., Ishida T., Kiwada H
    • Journal Title

      J. Control. Release

      Volume: 151 Pages: 149-154

    • DOI

      10.1016/j.jconrel.2010.12.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Journal Article] Anti-PEG IgM production by siRNA encapsulated in a PEGylated lipid nanocarrier is dependent on the sequence of the siRNA.2011

    • Author(s)
      Tagami T., Uehara Y., Moriyoshi N., Ishida T., Kiwada H.
    • Journal Title

      J.Control.Release in press

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] A double-modulation strategy in cancer treatment with a chemotherapeutic agent and siRNA2011

    • Author(s)
      Nakamura, K, Abu Lila A., Matsunaga, M., Doi, Y., Ishida, T., Kiwada, H.
    • Journal Title

      Mol. Ther.

      Volume: 19 Pages: 2040-2047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Evasion of the accelerated blood clearance phenomenon by coating of nanoparticles with various hydrophilic polymers.2010

    • Author(s)
      Ishihara T., Maeda T., Sakamoto H., Takasaki N., Shigyo M., Ishida T., Kiwada H., Mizushima Y., Mizushima T.
    • Journal Title

      Biomacromolecules 11

      Pages: 2700-2706

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] CpG motifs in pDNA-sequences increase anti-PEG IgM production induced by PEG-coated pDNA-lipoplexes.2010

    • Author(s)
      Tagami, T., Nakamura, K., Shimizu, T., Yamazaki, N., Ishida, T., Kiwada, H.
    • Journal Title

      J.Control.Release 142

      Pages: 160-166

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer.2010

    • Author(s)
      Eto Y., Yoshioka Y., Ishida T., Yao X., Morishige T., Narimatsu S., Mizuguchi H., Mukai Y., Okada N., Kiwada H., Nakagawa S.
    • Journal Title

      Biol.Pharm.Bull. 25

      Pages: 149-154

    • NAID

      130000322353

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Sequential administration with oxaliplatin-containing PEG-coated cationic liposomes promotes a significant delivery of subsequent dose into murine solid tumor2010

    • Author(s)
      Abu Lila, A., Doi, Y., Nakamura, K., Ishida, T., Kiwada, H.
    • Journal Title

      J. Control. Release

      Volume: 142 Pages: 167-173

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Combination therapy of metronomic S-1 dosing with oxaliplatin-containing PEG-coated liposome improves antitumor activity in a murine colorectal tumor model2010

    • Author(s)
      Doi Y., Okada T., Matsumoto H., Ichihara M., Ishida T., Kiwada, H.
    • Journal Title

      Cancer Sci.

      Volume: 101 Pages: 2470-2475

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes.2010

    • Author(s)
      Koide H., Asai, T., Hatanaka, K., Akai, S., Ishii, T., Kenjo, E., Ishida, T., Kiwada, H., Tsukada, H., Oku, N.
    • Journal Title

      Int.J.Pharm. 392

      Pages: 218-223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Targeting anticancer drugs to tumor vasculature using cationic liposomes2010

    • Author(s)
      Abu Lila, A., Ishida, T., Kiwada, H.
    • Journal Title

      Pharm. Res.

      Volume: 27 Pages: 1171-1183

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model.2009

    • Author(s)
      Abu-Lila, A, Suzuki, T., Doi. Y. Ishida, T., Kiwada, H.,
    • Journal Title

      J. Control. Release, 134

      Pages: 18-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] Recent advances in tumor vasculature targeting using liposomal drug delivery systems2009

    • Author(s)
      Abu Lila, A., Ishida, T., Kiwada, H.
    • Journal Title

      Expert Opin. Drug Deliv.

      Volume: 6 Pages: 1297-1309

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model2009

    • Author(s)
      Ishida, T.
    • Journal Title

      J. Control. Release 134

      Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] Accelerated blood clearance phenomenon upon repeated injection of PEG-modified PLA-nanoparticles.2009

    • Author(s)
      Ishihara, T., Takeda, M., Sakamoto, H., Kimoto, A., Kobayashi, C., Takasaki, N., Yuki, K., Tanaka, K., Takenaga, M., Igarashi, R., Maeda, T., Yamakawa, N., Okamoto, Y., Otsuka, M., Ishida, T., Kiwada, H.
    • Journal Title

      Pharm.Res. 26

      Pages: 2270-2279

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model.2009

    • Author(s)
      Ishida, T.
    • Journal Title

      J.Control. Release 134

      Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model2009

    • Author(s)
      Ishida, T.
    • Journal Title

      J. Control. Release 134

      Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20015033
  • [Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model.2009

    • Author(s)
      Ishida, T., Shiraga, E., Kiwada, H.,
    • Journal Title

      J. Control. Release 134

      Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] Oxaliplatin encapsulated in PEG-coated cationic liposomes induces significant tumor growth suppression via a dual-targeting approach in a murine solid tumor model2009

    • Author(s)
      Abu Lila, A., Kizuki, S., Doi, Y., Suzuki, T., Ishida, T., Kiwada, H.
    • Journal Title

      J. Control. Release

      Volume: 137 Pages: 8-14

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Synergistic antitumor activity of metronomic dosing of cyclophosphamide in combination with doxorubicin-containing PEGylated liposomes in a murine solid tumor model2009

    • Author(s)
      Ishida, T., Shiraga, E., Kiwada, H.
    • Journal Title

      J. Control. Release

      Volume: 134 Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Oxaliplatin targeting to angiogenic vessels by PEGylated cationic liposomes suppresses the angiogenesis in a dorsal air sac mouse model2009

    • Author(s)
      Abu-Lila, A, Suzuki, T., Doi, Y., Ishida, T., Kiwada, H.
    • Journal Title

      J. Control. Release

      Volume: 134 Pages: 18-25

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Journal Article] Effect of siRNA in PEG-coated siRNA-lipoplex on anti-PEG IgM production.2009

    • Author(s)
      Tagami, T., Nakamura, K., Shimizu, T., Ishida, T., Kiwada, H.
    • Journal Title

      J.Control.Release 137

      Pages: 234-240

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] A metronomic schedule of cyclophosphamide combined with PEGylated liposomal doxorubicin has a highly antitumor effect in an experimental pulmonary metastatic mouse model.2008

    • Author(s)
      Shiraga, E., Barichello, J.M., Ishida, T., Kiwada, H.,
    • Journal Title

      Int. J. Pharm., 353

      Pages: 65-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats.2008

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      J. Control. Release 126

      Pages: 162-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Accelerated blood clearance (ABC) phenomenon upon repeated injection of PEGylated liposomes.2008

    • Author(s)
      Ishida, T., Kiwada, H.
    • Journal Title

      Int.J.Pharm. 354

      Pages: 56-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Disappearance of the angiogenic potential of endothelial cells caused by Argonaute2 knockdown.2008

    • Author(s)
      Suzuki, Y., Matsushita, S., Yonezawa, S., Yokota, J., Katanasaka, Y. Ishida, T., Dcwa, T., Kiwada,, H., Nango, N., Oku, N.,
    • Journal Title

      Biochem. Biophys. Res. Commun., 368

      Pages: 243-248

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] The contribution of phagocytic activity of liver macrophages to the accelerated blood clearance (ABC) phenomenon of PEGylated liposomes in rats.2008

    • Author(s)
      Ishida, T., Kashima, S., Kiwada, H.
    • Journal Title

      J.Control.Release 126

      Pages: 162-165

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Particle size-dependent triggering of accelerated blood clearance phenomenon.2008

    • Author(s)
      Koide H., Asai, T., Hatanaka, K., Urakami, T., Ishii, T., Kenjo, E., Nishihara, M., Yokoyama, M., Ishida, T., Kiwada, H., Oku, N.
    • Journal Title

      Int.J.Pharm. 362

      Pages: 197-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Journal Article] Tumor targeting of doxorubicin by and MT1-MMP antibody-modified PEG liposomes.2007

    • Author(s)
      Hatakeyama, H., Akita, H., Ishida, E., Hashimoto, K., Kobayashi, H., Aoki, T., Yasuda, J., Obata, K., Kikuchi, K., Ishida, T., Kiwada, H., Harashima, H.,
    • Journal Title

      Int. J. Pharm., 342

      Pages: 194-200

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] PEGylated liposomes elicit an anti-PEG IgM response in a T-cells independent manner.2007

    • Author(s)
      Ishida, T., et. al.
    • Journal Title

      J. Control. Release 122

      Pages: 349-355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18015036
  • [Journal Article] In vitro efficacy of a sterically stabilized immunoliposomes targeted to membrane type 1 matrix metalloproteinase (MT1-MMP).2007

    • Author(s)
      Atobe K., Ishida T., Ishida, E., Hashimoto K., Kobayashi H., Yasuda J., Aoki, T, Obata K, Kikuchi H., Akita, H., Asai, T, Harashima, H., Oku, N., Kiwada, H.,
    • Journal Title

      Biol. Pharm. Bull., 30

      Pages: 972-978

    • NAID

      110006273300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Journal Article] Spleen plays an important role in the induction of accelerated blood clearance o PEGylated liposomes.2006

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      Journal of Controlled Release 115

      Pages: 243-250

    • Data Source
      KAKENHI-PROJECT-18015036
  • [Journal Article] Development of pH-sensitive liposomes that efficiently retain encapsulated doxorubicin (DXR) in blood.2006

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      International Journal of Pharmaceutics 309

      Pages: 94-100

    • Data Source
      KAKENHI-PROJECT-18015036
  • [Journal Article] Injection of PEGylated liposomes in rats elicits PEG-secifc IgM, which is responsible for rapid elimination of a second dose of PEGylated liposomes.2006

    • Author(s)
      Ishida T., et al.
    • Journal Title

      Journal of Controlled Release 112

      Pages: 15-25

    • Data Source
      KAKENHI-PROJECT-18015036
  • [Journal Article] Development of pH-sensitive liposomes that efficiently retain encapsulated doxorubicin (DXR) in blood.2006

    • Author(s)
      Tatsuhiro Ishida
    • Journal Title

      International Journal of Pharmaceutics 309

      Pages: 94-100

    • Data Source
      KAKENHI-PROJECT-16790105
  • [Journal Article] Stimulatory effect of polyethylene glycol (PEG) on gene expression in mouse liver following hydrodynamics-based transfection.2006

    • Author(s)
      Ishida, T., et al.
    • Journal Title

      Journal of Gene Medicine 8

      Pages: 324-334

    • Data Source
      KAKENHI-PROJECT-18015036
  • [Patent] リポソームに抗体結合能を付与するペプチド、および当該ペプチドで修飾されたリボソーム2007

    • Inventor(s)
      篠原康雄、際田弘志、石田竜弘、山崎尚志, 片岡正俊
    • Industrial Property Rights Holder
      国立大学法人徳島大学、独立行政法人産業技術総合研究所
    • Industrial Property Number
      2007-288728
    • Filing Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-17076011
  • [Patent] リポソームに抗体結合能を付与するペプチド、および当該ペプチドで修飾されたリポソーム2007

    • Inventor(s)
      片岡 正俊、 篠原 康雄、 際田 弘志、 石田 竜弘、 山崎 尚志
    • Industrial Property Rights Holder
      産総研 徳島大学
    • Industrial Property Number
      2007-288728
    • Filing Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-17076011
  • [Presentation] イオン液体を用いたGLP-1受容体作動薬の腸管吸収性検討2021

    • Author(s)
      角南尚哉、安藤英紀、丸山敦也、三輪泰司、濱本英利、清水太郎、異島優、石田竜弘
    • Organizer
      日本薬学会第141年会(Web開催)
    • Data Source
      KAKENHI-PROJECT-20K21898
  • [Presentation] 免疫抑制剤フィンゴリモドがマクロファージへの脂質蓄積に与える影響2021

    • Author(s)
      立花 洸季、小川 真依、石田 竜弘、異島 優、奥平 桂一郎
    • Organizer
      日本薬学会 第141年会
    • Data Source
      KAKENHI-PROJECT-20H04124
  • [Presentation] Immunological response to PEGylated liposomes: production of anti-PEG antibodies and their affection on PK of second dose.2019

    • Author(s)
      Ishida, T.
    • Organizer
      17th International Symposium on Blood Substitutes & Oxygen Therapeutics
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19KK0279
  • [Presentation] 難治性膵臓がんにおけるアルブミンナノ粒子のサイズ最適化の検討2019

    • Author(s)
      異島優、木下遼、平川尚樹、石田竜弘、小田切優樹、丸山徹
    • Organizer
      第30回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 難治性膵臓がんへの高い移行性を有するアルブミンナノ粒子の開発2019

    • Author(s)
      平川尚樹、異島優、木下遼、清水太郎、丸山徹、奥平桂一郎、石田竜弘
    • Organizer
      日本薬剤学会第34年会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 両親媒性ナノフィブリル化バクテリアセルロース(Fibnano)の放出制御型がん治療製剤への応用2019

    • Author(s)
      赤木俊介、安藤英紀、田島健次、松島得雄、草野貴友、石田竜弘
    • Organizer
      セルロース学会第26回年次大会
    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Presentation] 腫瘍ターゲティングとEPR効果2019

    • Author(s)
      石田竜弘
    • Organizer
      日本薬物動態学会第34回年会(茨城、つくば国際会議場)
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19925
  • [Presentation] 細胞膜透過型アルブミンの細胞内移行機序の解明~マクロピノサイトーシス誘導とエンドソーム脱出経路~2019

    • Author(s)
      一水翔太、渡邊博志、前田仁志、清水太郎、異島優、石田竜弘、二木史朗、小田切優樹、丸山徹
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 両親媒性ナノフィブリル化バクテリアセルロースを基剤とした放出制御型Paclitaxel製剤の開発2019

    • Author(s)
      赤木俊介、安藤英紀、田島健次、松島得雄、草野貴友、石田竜弘
    • Organizer
      日本薬剤学会第34年会
    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Presentation] 抗体医薬を用いたがん治療に対するEPR増強剤SNO-HSA-dimerの効果2019

    • Author(s)
      異島優、木下遼、池田真由美、丸山徹、小田切優樹、石田竜弘
    • Organizer
      第35回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 血清アルブミンの酸化ストレス応答を模倣した新規抗酸化剤の設計2019

    • Author(s)
      池田真由美、異島優、清水太郎、安藤英紀、奥平桂一郎、渡邊博志、丸山徹、小田切優樹、石田竜弘
    • Organizer
      日本薬剤学会第34年会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] Functional Elucidation of Polysulfides In Serum Albumin and Development of Biomimetic Donor of Polysulfides.2019

    • Author(s)
      Ikeda, M., Ishima, Y., Watanabe, H., Maruyama, T., Otagiri, M., Ishida, T.
    • Organizer
      2019 CRS Annual Meeting & Exposition.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 物理化学的性質の異なるナノフィブリル化バクテリアセルロース(NFBC)を用いたPTX製剤の開発とがん治療評価2019

    • Author(s)
      赤木俊介、安藤英紀、田島健次、松島得雄、草野貴友、石田竜弘
    • Organizer
      第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-19H02549
  • [Presentation] イオン液体を用いた新規インスリン含有経皮吸収製剤は糖尿病治療薬になりうる2019

    • Author(s)
      佐々井雅樹、清水太郎、奥平桂一郎、異島優、石橋賢樹、三輪泰司、濱本英利、石田竜弘
    • Organizer
      第28回DDSカンファランス(静岡、グランシップ)
    • Data Source
      KAKENHI-PROJECT-18K19925
  • [Presentation] ヒト血清アルブミンに存在するポリスルフィドによるユニークな酸化ストレス応答2019

    • Author(s)
      池田真由美、異島優、酒井真紀、清水太郎、安藤英紀、渡邊博志、丸山徹、小田切優樹、石田竜弘
    • Organizer
      第19回日本NO学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] PEG修飾リポソームに対する免疫反応(ABC現象)の解明とワクチンへの応用2018

    • Author(s)
      石田竜弘
    • Organizer
      日本薬学会北海道支部・特別講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] 新規腫瘍DDSキャリアである共有結合型アルブミンナノ粒子の有用性評価2018

    • Author(s)
      木下遼、異島優、渡邊博志、清水太郎、石田竜弘、小田切優樹、丸山徹
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] ポリスルフィド付加血清アルブミンによるメラニン産生の抑制2018

    • Author(s)
      池田真由美、清水太郎、丸山徹、小田切優樹、異島優、石田竜弘
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 一酸化窒素を利用した血管透過性制御とがん治療応用2018

    • Author(s)
      異島優、木下遼、池田真由美、丸山徹、小田切優樹、石田竜弘
    • Organizer
      日本薬学会第139年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 生物由来健康食品に含まれる活性イオウ分子種の検出2018

    • Author(s)
      長船裕輝、池田真由美、酒井真紀、清水太郎、異島優、石田竜弘
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 共有結合型アルブミンナノ粒子を用いたセラノスティックナノDDS抗がん剤の開発2018

    • Author(s)
      平川尚樹、異島優、木下遼、清水太郎、丸山徹、奥平桂一郎、石田竜弘
    • Organizer
      第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] アルブミン製剤中のサルフェン硫黄含有量の差異と抗酸化能の評価2018

    • Author(s)
      酒井真紀、池田真由美、今福匡司、清水太郎、丸山徹、小田切優樹、異島優、石田竜弘
    • Organizer
      第71回日本酸化ストレス学会・第18回日本NO学会合同学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] A Novel S-Sulfhydrated Human Serum Albumin Preparation Suppresses Melanin Synhtesis.2018

    • Author(s)
      Ikeda, M., Tasaka, N., Shimizu, T., Ishima, Y., Ishida, T.
    • Organizer
      5th World Congress on Hydrogen Sulfide in Biology&Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 多剤耐性菌および真菌に対するS‐ニトロソ化Alpha1―酸性糖蛋白質の効果2018

    • Author(s)
      異島優、石田竜弘, 金城雄樹、丸山徹、小田切優樹
    • Organizer
      医療薬学フォーラム 2018
    • Invited
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 共有結合型アルブミンナノ粒子をキャリアとしたナノDDS抗がん剤の開発及び有用性評価2018

    • Author(s)
      平川尚樹、木下遼、異島優、清水太郎、丸山徹、奥平桂一郎、石田竜弘
    • Organizer
      第34回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] Immunological responses against PEGylated liposomes: Application for cancer vaccine.2018

    • Author(s)
      Ishida, T.
    • Organizer
      13th France-Japan Drug Delivery Systems Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19925
  • [Presentation] 生体液中の活性イオウ分子種の検出と機能解明2018

    • Author(s)
      池田真由美、異島優、渡邊博志、赤池孝章、丸山徹、小田切優樹、石田竜弘
    • Organizer
      第40回生体膜と薬物の相互作用シンポジウム
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 新規抗菌剤SNO-AGPの多剤耐性菌に対する克服効果2018

    • Author(s)
      異島優、渡辺佳織、小田切優樹、石田竜弘、丸山徹
    • Organizer
      日本薬剤学会第33年会
    • Data Source
      KAKENHI-PROJECT-18H02587
  • [Presentation] 微粒子製剤に対する免疫反応:PEG修飾リポソームに対するABC現象とCARPA2018

    • Author(s)
      石田竜弘
    • Organizer
      製剤種差検討会第7回事例報告会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K19925
  • [Presentation] Anti-polyethylene-glycol Antibody Response to PEGylated Nanoparticles.2018

    • Author(s)
      Ishida, T.
    • Organizer
      CLINAM summit 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15KK0310
  • [Presentation] Immunological responses against PEGylated liposomes: the application of ABC phenomenon into cancer vaccine.2018

    • Author(s)
      Ishida, T., Shimizu, T.
    • Organizer
      12th International Symposium on Nanomedicine
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K19925
  • [Presentation] Immunological responses against PEGylated materials: the accelerated blood clearance (ABC) issue.2017

    • Author(s)
      Ishida, T.
    • Organizer
      International Symposium on Nanomedicine 2017
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15108
  • [Presentation] 化学修飾DNAを利用したRNA創薬2017

    • Author(s)
      南川典昭、田良島典子、高橋知樹、山本清義、金城望、安藤英紀、石田竜弘、小暮健太朗
    • Organizer
      第33回日本DDS学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04656
  • [Presentation] 補体活性化能を持つポリマー修飾リポソームによる脾臓辺縁帯B細胞標的化に関する検討2017

    • Author(s)
      清水太郎、粟田瑞月、吉岡千尋、異島優、石田竜弘
    • Organizer
      日本薬剤学会第32年会
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] 脾臓辺縁帯B細胞標的化能をもつポリマー修飾リポソームを用いた静注型ワクチン開発に関する検討2017

    • Author(s)
      吉岡千尋、粟田瑞月、渡辺優希、清水太郎、石田竜弘
    • Organizer
      第33回日本DDS学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K15108
  • [Presentation] Immunological response to PEGylated nanoparticles: Anti-PEG antibody issues.2017

    • Author(s)
      Ishida, T.
    • Organizer
      ILS Liposome Advances and Liposome Research Days Combined Conference.
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] リポソーム化抗がん剤投与が引き起こす腫瘍免疫細胞の影響2016

    • Author(s)
      高山拓磨、清水太郎、鵜川真実、石田竜弘
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場・岐阜都ホテル(岐阜県・岐阜市)
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] Anti-PEG immunity against PEGylated materials.2016

    • Author(s)
      Ishida, T.
    • Organizer
      International Workshop for Immune Effects of Nanomedicines: Clinical and Experimental Evidence, Prediction and Prevention.
    • Place of Presentation
      Budapest, Hungary
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] PEG修飾有機シリカ粒子に対する免疫応答に関する検討2016

    • Author(s)
      中見祥一、清水 太郎、中村 教泰、石田 竜弘
    • Organizer
      第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Place of Presentation
      就実大学薬学部(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-16K15108
  • [Presentation] Development of a RNAi-based anticancer drug.2016

    • Author(s)
      Ishida, T.
    • Organizer
      12th France-Japan Drug Delivery Systems Symposium
    • Place of Presentation
      Paris, France
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] ヒトにおける抗PEG抗体保有率の調査2016

    • Author(s)
      清水太郎、久保幸代、石田竜弘
    • Organizer
      日本薬剤学会第31年会
    • Place of Presentation
      長良川国際会議場・岐阜都ホテル(岐阜県・岐阜市)
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] 抗がん剤封入リポソームとの併用によるがんワクチン効果の増強に関する検討2016

    • Author(s)
      竹瀬俊輔、高山拓磨、西尾美穂、清水太郎、石田竜弘
    • Organizer
      第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Place of Presentation
      就実大学薬学部(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-16K15108
  • [Presentation] ポリエチレングリコール修飾タンパク製剤Pegasysに対する抗PEG IgM応答2016

    • Author(s)
      本藤栄里、美馬優、清水太郎、石田竜弘
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-27
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] PEGリポソームへのアルブミン修飾は、抗PEG抗体の産生を抑制する2016

    • Author(s)
      山﨑 仁王、異島 優、清水 太郎、石田 竜弘
    • Organizer
      第55回日本薬学会・日本薬剤師会・日本病院薬剤師会 中国四国支部学術大会
    • Place of Presentation
      就実大学薬学部(岡山県岡山市)
    • Data Source
      KAKENHI-PROJECT-16K15108
  • [Presentation] Gene silencing via RNA interference (RNAi) machinery using 4'-thioDNA as an artificial template2015

    • Author(s)
      Noriko Tarashima, Nozomi Kinjyo, Takamitsu Kojima, Hidenori Ando,Tatsuhiro Ishida, Noriaki Minakawa
    • Organizer
      The 42nd International Symposium on Nucleic Acids Chemistry
    • Place of Presentation
      I-messae hall(Himeji,Japan )
    • Year and Date
      2015-09-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04656
  • [Presentation] 胃がん腹膜播種モデルにおけるオキサリプラチン封入リポソーム静脈内投与による腫瘍増殖抑制効果2015

    • Author(s)
      渡邉奈美、安藤英紀、石田竜弘
    • Organizer
      第31回日本DDS学会学術集会
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2015-07-03
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] オキサリプラチン封入PEG修飾リポソーム製剤投与ラットの後肢皮膚組織における手足症候群様症状の評価2015

    • Author(s)
      西田健太朗、柏木美咲、室木究、柴俊輔、池田理沙、石田竜弘、長澤一樹
    • Organizer
      第53回日本癌治療学会学術集会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Year and Date
      2015-10-29
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] PEG化製剤に対するanti-PEG IgM結合特性に関する検討2015

    • Author(s)
      久保幸代、本藤栄里、阿部遼、美馬優、清水太郎、石田竜弘
    • Organizer
      第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      高知テルサ(高知県高知市)
    • Year and Date
      2015-10-31
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] ヒドロキシ末端PEG修飾リポソームを用いた静注型ワクチン開発に関する基礎的検討2015

    • Author(s)
      吉岡千尋、粟田瑞月、渡辺優希、清水太郎、石田竜弘
    • Organizer
      第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      高知テルサ(高知県高知市)
    • Year and Date
      2015-10-31
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Presentation] FTY720併用によるドキシルの細胞内取り込み向上に関する検討2015

    • Author(s)
      清水太郎、高橋孝典、石田竜弘
    • Organizer
      第37回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      熊本大学薬学部(熊本県熊本市)
    • Year and Date
      2015-11-20
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Presentation] P E G修飾製剤に対する免疫応答~抗P E G - I g Mの分泌誘導~2015

    • Author(s)
      石田竜弘
    • Organizer
      第5回薬剤学セミナー
    • Place of Presentation
      熊本大学薬学部(熊本県熊本市)
    • Year and Date
      2015-07-21
    • Invited
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Presentation] IV 投与PEGリポソームに対するanti-PEG IgM応答への腹腔内免疫細胞の関与2015

    • Author(s)
      阿部遼、清水太郎、石田竜弘
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] PEG修飾タンパク質Pegasys®投与によるABC現象誘導2015

    • Author(s)
      本藤栄里、美馬優、際田弘志、石田竜弘
    • Organizer
      日本薬剤学会第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-15H04639
  • [Presentation] PEG修飾リポソームの投与経路の違いがanti-PEG IgM分泌に及ぼす影響に関する検討(第2報)2014

    • Author(s)
      阿部遼、清水太郎、石田竜弘、際田弘志
    • Organizer
      第23回DDSカンファランス
    • Place of Presentation
      清水テルサ(静岡県、静岡市)
    • Year and Date
      2014-09-05
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Presentation] In vivo imaging systemによる胸腔内投与リポプレックスの動態評価2014

    • Author(s)
      加藤千尋、石田竜弘、際田弘志
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      大宮ソニックシティビル(埼玉県さいたま市)
    • Year and Date
      2014-05-20
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] 脾臓辺縁帯B細胞による抗原封入PEG修飾リポソームの濾胞への輸送現象を利用した抗腫瘍免疫誘導効果2014

    • Author(s)
      清水太郎、渡辺優希、美馬優、石田竜弘、際田弘志
    • Organizer
      日本薬剤学会第29年会
    • Place of Presentation
      大宮ソニックシティビル(埼玉県さいたま市)
    • Year and Date
      2014-05-20
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] In vivo imaging systemによる胸腔内投与リポプレックスの動態評価2014

    • Author(s)
      加藤千尋、石田竜弘、際田弘志
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学薬学部(東京都港区)
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] Anti-PEG immunity against PEGylated materials.2014

    • Author(s)
      Ishida, T
    • Organizer
      11th DDS Symposium France-Japan
    • Place of Presentation
      淡路夢舞台国際会議場(兵庫県淡路市)
    • Year and Date
      2014-10-06
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenvironment.2014

    • Author(s)
      Ishida, T.
    • Organizer
      Synchrotron Radiation in Nano-medicine and Advanced Health Care (SRNAHC)
    • Place of Presentation
      KONAN University (兵庫県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] ナノテクノロジーを用いた薬物動態制御の可視化2014

    • Author(s)
      石田竜弘
    • Organizer
      高分子学会九州支部・九州有機材料研究グループ研究会
    • Place of Presentation
      北九州市立大学(福岡県)
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] リポソームからのPemetrexedの放出性が胸腔内移植腫瘍の増殖に与える影響2014

    • Author(s)
      小林早紀子、Amr Abu-Lila、石田竜弘、際田弘志
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] Shotgun分析を用いたPEG修飾リポソーム結合タンパク質の網羅的解析2014

    • Author(s)
      川西宗平、橋本洋佑、清水太郎、際田弘志、石田竜弘
    • Organizer
      第23回DDSカンファランス
    • Place of Presentation
      清水テルサ(静岡県、静岡市)
    • Year and Date
      2014-09-05
    • Data Source
      KAKENHI-PROJECT-26670079
  • [Presentation] マウス肺癌細胞に対するFTY720とドキシルとの併用効果に関する検討2014

    • Author(s)
      清水太郎、高橋孝典、石田竜弘、際田弘志
    • Organizer
      第30回日本DDS学会学術集会
    • Place of Presentation
      慶應義塾大学薬学部(東京都港区)
    • Year and Date
      2014-07-30
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] 転移性肝臓がんの存在がオキサリプラチン封入PEG修飾リポソームの肝移行性へ与える影響2014

    • Author(s)
      藤原由佳子、中村浩之、石田竜弘、際田弘志
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本大学(熊本県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] Accelerated blood clearance phenomenon upon PEGylated protein.2013

    • Author(s)
      Mima, Y., Hashimoto, Y., Shimizu, T., Ishida, T., Kiwada, H.,
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] 抗がん剤による腫瘍内微小環境変化を利用した新規DDSの開発2013

    • Author(s)
      石田竜弘、際田弘志
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ(京都府)
    • Invited
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] 固形がんにおける抗がん剤封入PEG修飾リポソームとshRNA含有lipoplexによるがん治療法の確立2013

    • Author(s)
      田中真生、中村浩之、森吉直人、石田竜弘、際田弘志
    • Organizer
      第52回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      松山大学(愛媛県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] 腫瘍内血管系の動的変化がPEG修飾リポソームの腫瘍内分布に及ぼす影響2013

    • Author(s)
      西尾美穂、中村浩之、石田竜弘、際田弘志
    • Organizer
      第22回DDSカンファランス
    • Place of Presentation
      グランシップ静岡(静岡県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] Serum anti-PEG IgM concentration is a determinant factor on hepatic accumulation of PEGylated liposome in the accelerated blood clearance phenomenon.2013

    • Author(s)
      Hashimoto, Y., Shimizu, T., Ishida, T., Kiwada, H.,
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] In vivo imaging systemを用いたリポソーム胸腔内投与後の体内動態の評価2013

    • Author(s)
      加藤千尋、Amr Abu-Lila、石田竜弘、際田弘志
    • Organizer
      第52回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      松山大学(愛媛県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] 抗がん剤による腫瘍内微小環境変化を利用した新規DDSの開発2013

    • Author(s)
      石田竜弘, 際田弘志
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2013-07-04
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] 脾臓辺縁体B細胞によるPEG修飾リポソームの濾胞への輸送現象を利用した特異的抗体誘導効果2013

    • Author(s)
      清水太郎、渡辺優希、美馬優、橋本洋祐、石田竜弘、際田弘志
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      愛知県産業労働センター ウインクあいち(愛知県)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] PEG修飾リポソームを用いた濾胞への高原送達による抗体誘導効果2013

    • Author(s)
      石田竜弘
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-23659082
  • [Presentation] Potentiation of specific antibody response against antigen encapsulated in PEGylated liposomes via active transport of the liposomes from marginal zone into follicle.2013

    • Author(s)
      Shimizu, T., Ishida, T., Kiwada, H.
    • Organizer
      5th Asian Arden Conference
    • Place of Presentation
      愛知学院大学(愛知県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] PEG修飾剤末端構造が与えるABC現象誘導への影響に関する検討2013

    • Author(s)
      藤田理紗子、橋本洋佑、清水太郎、石田竜弘、際田弘志
    • Organizer
      第22回DDSカンファランス
    • Place of Presentation
      グランシップ静岡(静岡県)
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] siRNA搭載PEG修飾リポプレックス投与時に誘起される抗PEG IgM分泌亢進機構の解明2013

    • Author(s)
      橋本洋佑、石田竜弘、際田弘志
    • Organizer
      第35回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      東京大学(東京都)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] 腫瘍内微小環境の能動的制御に基づく腫瘍選択的デリバリーシステムの開発2013

    • Author(s)
      石田竜弘
    • Organizer
      日本薬学会第133年会
    • Place of Presentation
      パシフィコ横浜(神奈川県)(招待講演)
    • Year and Date
      2013-03-30
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] 高用量PEG修飾リポソームを用いたABC現象の回避2013

    • Author(s)
      美馬優、橋本洋祐、清水太郎、石田竜弘、際田弘志
    • Organizer
      第29回日本DDS学会学術集会
    • Place of Presentation
      京都テルサ(京都府)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] Transport of PEGylated liposomes to follicle induced by pre-stimulation of empty liposomes: Potentiating specific antibody responses against antigen encapsulated in the liposomes.2013

    • Author(s)
      Shimizu, T., Ishida, T., Kiwada, H.
    • Organizer
      40th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Hawaii Convention Center (USA)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] 高用量PEG修飾リポソームによる抗PEG IgMの分泌抑制に関する検討2013

    • Author(s)
      美馬優、橋本洋佑、清水太郎、石田竜弘、際田弘志
    • Organizer
      第22回DDSカンファランス
    • Place of Presentation
      グランシップ静岡(静岡県)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] siRNA搭載PEG修飾リポプレックス投与時に惹起される抗PEG IgM分泌応答機構の解明2013

    • Author(s)
      橋本洋祐、清水太郎、石田竜弘、際田弘志
    • Organizer
      日本薬剤学会第28年会
    • Place of Presentation
      愛知県産業労働センター ウインクあいち(愛知県)
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenvironment.2012

    • Author(s)
      Ishida, T.
    • Organizer
      10th DDS Symposium France-Japan
    • Place of Presentation
      Grand Hotel de Bordeaux(フランス)(招待講演)
    • Year and Date
      2012-10-13
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開2012

    • Author(s)
      石田 竜弘
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2012-03-20
    • Data Source
      KAKENHI-PROJECT-23659082
  • [Presentation] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開2012

    • Author(s)
      石田竜弘
    • Organizer
      日本薬学会第126年会
    • Place of Presentation
      北海道大学(北海道)(招待講演)
    • Year and Date
      2012-03-30
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] 腫瘍内微小環境の能動的制御に基づくsiRNAデリバリー技術の開発とがん治療への展開2012

    • Author(s)
      石田竜弘
    • Organizer
      日本薬学会第132年会(招待講演)
    • Place of Presentation
      北海道大学(北海道)
    • Data Source
      KAKENHI-PROJECT-23659082
  • [Presentation] Improved intratumoral delivery of PEG-coated siRNA-lipoplexes by combination with metronomic S-1 dosing in murine solid tumor model.2012

    • Author(s)
      Ishida, T.
    • Organizer
      Oligonucleotide Delivery : Biology, Engineering and Development
    • Place of Presentation
      Hernstein (オーストリア)(招待講演)
    • Year and Date
      2012-10-08
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] PEG 修飾リポソームと脾臓辺縁帯 B 細胞との相互作用に関する検討2012

    • Author(s)
      石田 竜弘
    • Organizer
      日本薬学会第132 年会
    • Place of Presentation
      北海道大学(札幌市)
    • Year and Date
      2012-03-29
    • Data Source
      KAKENHI-PROJECT-23659082
  • [Presentation] Activation of splenic marginal zone B cell by PEGylated liposome with lower dose: triggering transport of antigen-containing second dose PEGylated liposome from marginal zone to follicle2012

    • Author(s)
      Ishida, T
    • Organizer
      39th Annual Meeting & Exposition of the Controlled Release Society
    • Place of Presentation
      Centre des Congress de Quebec(カナダケベック)
    • Year and Date
      2012-07-16
    • Data Source
      KAKENHI-PROJECT-23659082
  • [Presentation] 腫瘍内微小環境の能動的制御による新規DDSの開発と治療への応用2012

    • Author(s)
      石田竜弘
    • Organizer
      創剤フォーラム第18回若手研究会
    • Place of Presentation
      長井記念ホール(徳島県)(招待講演)
    • Year and Date
      2012-11-17
    • Data Source
      KAKENHI-PROJECT-24390010
  • [Presentation] Improvement of tumor-targeting therapy with nanocarrier system by changing the tumor microenviroment2011

    • Author(s)
      Ishida, T., Kiwada, H.
    • Organizer
      2011 RCAA International Symposium Endogenous Ligands Modulating Anticancer Agents
    • Place of Presentation
      Seoul, Korea
    • Year and Date
      2011-02-11
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] PEG on nanocarriers induces anti PEG IgM production as a result of activation of immune system., Nano in Cancer : Linking Chemistry2011

    • Author(s)
      Hashiguchi Y., Shimizu T., Ichihara M., Ishida T., Kiwada H.
    • Organizer
      Biology and Clinical Applications in vivo
    • Place of Presentation
      Miami USA, Jan.
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Anti-PEG IgM分泌誘導においてPEG修飾剤末端構造が与える影響に関する検討2011

    • Author(s)
      石田 竜弘
    • Organizer
      第50回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      サンポートホール高松(高松市)
    • Year and Date
      2011-11-13
    • Data Source
      KAKENHI-PROJECT-23659082
  • [Presentation] 腫瘍内微小環境変化を利用した核酸デリバリー戦略2011

    • Author(s)
      石田竜弘
    • Organizer
      遺伝子・デリバリー研究会第11回夏期セミナー
    • Place of Presentation
      三翠園ホテル(高知県高知市)
    • Year and Date
      2011-08-09
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] 腫瘍内微小環境変化を利用した核酸デリバリー戦略2011

    • Author(s)
      石田竜弘
    • Organizer
      遺伝子・デリバリー研究会第11回夏期セミナー
    • Place of Presentation
      三翠園ホテル(高知県)(招待講演)
    • Year and Date
      2011-08-09
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] Biological responses against lipid membrane containing PEG2011

    • Author(s)
      Ishida, T., Kiwada, H
    • Organizer
      3rd International Symposium on Surface and Interface of Biomaterials (SIB2011)
    • Place of Presentation
      北海道大学学術交流会館(北海道札幌市)
    • Year and Date
      2011-07-14
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] Biological responses against lipid membrane containing PEG2011

    • Author(s)
      Ishida, T.
    • Organizer
      3rd International Symposium on Surface and Interface of Biomaterials (SIB2011)
    • Place of Presentation
      北海道大学(北海道)(招待講演)
    • Year and Date
      2011-07-14
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] PEG 修飾ナノキャリア投与時に惹起される免疫応答~抗PEG-IgM 分泌誘導とナノキャリアの体内動態への影響~2011

    • Author(s)
      石田竜弘
    • Organizer
      広島臓器移植セミナー
    • Place of Presentation
      広島大学医学部(広島県広島市)
    • Year and Date
      2011-08-10
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] PEG修飾ナノキャリア投与時に惹起される免疫応答~抗PEG-IgM分泌誘導とナノキャリアの体内動態への影響~2011

    • Author(s)
      石田竜弘
    • Organizer
      広島臓器移植セミナー
    • Place of Presentation
      広島大学(広島県)(招待講演)
    • Year and Date
      2011-08-10
    • Data Source
      KAKENHI-PROJECT-23390012
  • [Presentation] A novel double modulation strategy in cancer treatment with chemothera peutic agent and siRNA : S-1 improves siRNA accumulation and then Bcl-2 knockdown by the siRNA increases chemosensitivity of 5-FU.2011

    • Author(s)
      Ishida, T.
    • Organizer
      NANO IN CANCER : LINKING CHEMISTRY, BIOLOGY, AND CLINICAL APPLICATIONS IN VIVO
    • Place of Presentation
      Miami, USA
    • Year and Date
      2011-01-13
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] 腫瘍内微小環境変化を利用した核酸デリバリー戦略2011

    • Author(s)
      石田竜弘
    • Organizer
      遺伝子・デリバリー研究会第11回夏期セミナー
    • Place of Presentation
      三翠園ホテル(高知)(招待講演)
    • Year and Date
      2011-08-09
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] PEG修飾ナノキャリア生体内投与後に生ずる免疫活性化(ABC現象)機構解明に関する検討2010

    • Author(s)
      市原理子、石田竜弘、際田弘志
    • Organizer
      第19回DDSカンファランス
    • Place of Presentation
      (静岡)
    • Year and Date
      2010-09-04
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Sequential treatment, pre-dose with empty PEGylated liposome (SL) and second dose antigen-encapsulating SL, promotes activation in a primary immune response.2010

    • Author(s)
      Hashiguchi, Y., Shimizu, T., Ishida T., Kiwada H.
    • Organizer
      International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] 腫瘍内微小環境変化を利用したsiRNAデリバリーシステムの開発2010

    • Author(s)
      石田竜弘
    • Organizer
      第32回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      富山市
    • Year and Date
      2010-11-29
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] Immunostimulatory properties of liposomes containing PEG.2010

    • Author(s)
      Ishida, T., Kiwada, H.
    • Organizer
      International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] 腫瘍内微小環境変化を利用したsiRNAデリバリーシステムの開発2010

    • Author(s)
      石田竜弘、際田弘志
    • Organizer
      第32回生体膜と薬物の相互作用シンポジウム
    • Place of Presentation
      富山
    • Year and Date
      2010-11-29
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] 核酸デリバリーにおけるABC現象2010

    • Author(s)
      石田竜弘
    • Organizer
      遺伝子・デリバリー研究会第10回シンポジウム
    • Place of Presentation
      札幌市
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] 生体内動態検討を基盤としたリポソームDDSの開発2010

    • Author(s)
      石田竜弘
    • Organizer
      第26回日本DDS学会
    • Place of Presentation
      大阪市
    • Year and Date
      2010-06-18
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] 腫瘍へのsiRNAデリバリーシステムの開発~効果と安全性の観点から~2010

    • Author(s)
      石田竜弘
    • Organizer
      第47回薬剤学懇談会研究討論会
    • Place of Presentation
      高山市
    • Year and Date
      2010-06-24
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] Immunostimulatory properties of liposomes containing PEG2010

    • Author(s)
      Ishida, T.
    • Organizer
      International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
    • Place of Presentation
      Vancouver, Canada
    • Year and Date
      2010-08-06
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Spleen cells secret anti-PEG IgM following intravenous injection of PEGylated liposome.2010

    • Author(s)
      Ichihara, M., Imoto, A., Hashiguchi, Y., Uehara, Y., Ishida T., Kiwada H.
    • Organizer
      International Liposome Research Days & Lipids, Liposomes & Membrane Biophysics
    • Place of Presentation
      Vancouver, Canada
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] 腫瘍へのsiRNAデリバリーシステムの開発~効果と安全性の観点から~2010

    • Author(s)
      石田竜弘
    • Organizer
      第47回薬剤学懇談会研究討論会
    • Place of Presentation
      高山
    • Year and Date
      2010-06-24
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] 核酸デリバリーにおけるABC現象、遺伝子・デリバリー研究会2010

    • Author(s)
      石田竜弘、際田弘志
    • Organizer
      第10回シンポジウム
    • Place of Presentation
      (札幌)
    • Year and Date
      2010-06-03
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Elucidation of ABC phenomenon caused by repeat injection of PEGylated nanocarrier.2009

    • Author(s)
      Koide, H., Asai, T., Yokoyama, M., Ishida T., Kiwada H., Oku, N.
    • Organizer
      4th International Liposome Society Conference. Liposome advances : Progress in Drug and Vaccine Delivery
    • Place of Presentation
      London, UK
    • Year and Date
      2009-12-14
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] 核酸デリバリーにおけるaccelerated blood clearance (ABC)現象2009

    • Author(s)
      石田竜弘、際田弘志
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      (東京)
    • Year and Date
      2009-07-03
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Improvement of tumor-targeting therapy with nanocarriers by changing the tumor microenvironment2009

    • Author(s)
      Ishida, T., Kiwada, H.
    • Organizer
      2009 International Symposium of the Intelligent Drug Delivery System.
    • Place of Presentation
      Korea
    • Year and Date
      2009-04-30
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] Argonaute2標的siRNAリポプレックスを用いたがん治療戦略、学術シンポジウム4 RNAi医薬の展望. From Bench to Bedside-2009

    • Author(s)
      石田竜弘、浅井知浩、奥直人、際田弘志
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-23
    • Data Source
      KAKENHI-PROJECT-21689002
  • [Presentation] 核酸デリバリーにおける accelerated blood clearance (ABC)現象2009

    • Author(s)
      石田竜弘
    • Organizer
      第25回日本DDS学会
    • Place of Presentation
      東京都
    • Year and Date
      2009-07-03
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Interaction of PEGylated liposomes with splenic marginal zone B cells may trigger production of anti-PEG IgM in the ABC phenomenon.2008

    • Author(s)
      Shimizu, T., Ishida T., Kiwada H.
    • Organizer
      11^<th> Liposome Research Days conference
    • Place of Presentation
      Yokohama (Japan)
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] フッ素ピリミジン系抗がん剤とOxaliplatin(1-OHP)封入リポソーム併用療法に関する研究:1-OHP放出性の違いが効果と毒性に及ぼす影響2008

    • Author(s)
      平百合恵、土井祐輔、石田竜弘、際田弘志
    • Organizer
      第47回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
    • Place of Presentation
      岡山
    • Year and Date
      2008-11-09
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Effect of siRNA on anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon when formulated with PEGylated cationic liposome.2008

    • Author(s)
      Tagami, T., Nakamura, K., Shimizu, T., Ishida T., Kiwada H.
    • Organizer
      11^<th> Liposome Research Days conference
    • Place of Presentation
      Yokohama (Japan)
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] ナノキャリアーを用いた抗がん剤デリバリーシステムの開発におけるinvivo イメージングの有用性2008

    • Author(s)
      石田竜弘
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008

    • Author(s)
      Ishida, T.
    • Organizer
      11^<th> Liposome Research Days conference
    • Place of Presentation
      Yokohama (Japan)
    • Year and Date
      2008-07-20
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] S-1 metronomic chemotherapyとオキサリプラチン封入ナノキャリア併用療法の開発:相乗的効果増強機構の解明に関する研究2008

    • Author(s)
      土井祐輔、平百合恵、石田竜弘、際田弘志
    • Organizer
      第46回日本癌治療学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-30
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] PEG修飾微粒子キャリアー投与時の免疫反応2008

    • Author(s)
      石田竜弘
    • Organizer
      Frontier's Nanomedicine -Summer Workshop2008-
    • Place of Presentation
      北海道大学大学院薬学研究院(札幌)
    • Year and Date
      2008-08-05
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Unexpected immunological response against sterically stabilized, PEGylated, liposome after intravenous injection.2008

    • Author(s)
      石田竜弘, 際田弘志
    • Organizer
      International Symposium on "Nanotoxicology Assessment and Biomedical, Environmental Application of Fine Particles and Nanotubes" ISNT2008
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] ナノキャリアーを用いた抗がん剤デリバリーシステムの開発におけるin vivoイメージングの有用性2008

    • Author(s)
      石田竜弘
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB 2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-20015033
  • [Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008

    • Author(s)
      Ishida, T.
    • Organizer
      6^<th> international workshop on Drug Delivery Systems for Nanomedicine
    • Place of Presentation
      Prague (the Czech Republic)
    • Year and Date
      2008-10-05
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008

    • Author(s)
      Ishida, T.
    • Organizer
      11^<th> Liposome Research Days conference
    • Place of Presentation
      Yokohama (Japan)
    • Year and Date
      2008-07-20
    • Data Source
      KAKENHI-PROJECT-20015033
  • [Presentation] S-1を用いた Motronomic chemotherapyによって生じる腫瘍内微小環境の変化がもたらすリポソームの腫瘍内移行性の向上2008

    • Author(s)
      士井祐輔、平百合恵、石田竜弘、際田弘志
    • Organizer
      S-1を用いた Motronomic chemotherapyによって生じる腫瘍内微小環境の変化がもたらすリポソームの腫瘍内移行性の向上
    • Place of Presentation
      静岡
    • Year and Date
      2008-09-20
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Unexpected immunological response against sterically stabilized, PEGylated, liposome after intravenous injection.2008

    • Author(s)
      Ishida, T.
    • Organizer
      International Symposium on“Nanotoxicology Assessment and Biomedical, Environmental Application of Fine Particles and Nanotubes"(ISNT2008)
    • Place of Presentation
      Sapporo
    • Year and Date
      2008-06-17
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Accelerated blood clearance (ABC) phenomenon on PEGylated nanocarrier : Unexpected immune-reaction against PEGylated liposome.2008

    • Author(s)
      Shimizu, T., Ishida T., Kiwada H.
    • Organizer
      International Symposium on "Nanotoxicology Assessment and Biomedical, Environmental Application of Fine Particles and Nanotubes" (ISNT2008)
    • Place of Presentation
      Sapporo, Japan
    • Data Source
      KAKENHI-PROJECT-20390013
  • [Presentation] Improvement of tumortargeting therapy with nanocarrier by changing the tumor microenvironment2008

    • Author(s)
      Ishida,T., Kiwada, H.,
    • Organizer
      llth Liposome Research Days conference
    • Place of Presentation
      Yokohama(Japan)
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment2008

    • Author(s)
      Ishida, T.
    • Organizer
      6^<th> international workshop on Drug Delivery Systems for Nanomedicine
    • Place of Presentation
      Prague (the Czech Republic)
    • Year and Date
      2008-10-05
    • Data Source
      KAKENHI-PROJECT-20015033
  • [Presentation] ナノキャリアーを用いた抗がん剤デリバリーシステムの開発におけるin vivoイメージングの有用性2008

    • Author(s)
      石田竜弘
    • Organizer
      第31回日本分子生物学会年会第81回日本生化学会大会合同大会BMB2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-11
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Improvement of tumor targeting therapy with nanocarriers by changing the tumor microenvironment.2008

    • Author(s)
      Ishida, T., Kiwada, H.,
    • Organizer
      6th international workshop on Drug Delivery Systems for Nanomedicine,
    • Place of Presentation
      Prague (the Czech Republicl)
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Anti-MT1-MMPimmunoliposomeの血管内皮細胞(HUVEC)における内在化経路の検討2007

    • Author(s)
      下田かおり、跡部一孝、石田竜弘、橋本浩一、小林英夫、安田純子、青木隆則、小幡賢一、菊池寛、秋田英万、浅井知浩、原島秀吉、奥直人、際田弘志
    • Organizer
      Anti-MT1-MMPimmunoliposomeの血管内皮細胞(HUVEC)における内在化経路の検討
    • Place of Presentation
      熊本
    • Year and Date
      2007-06-14
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] 肺転移性melanoma細胞に対するシクロスファミドを用いたlow-dose metronomic chemotherapyにおけるドキソルビシン封入リポソームの併用効果の検討2007

    • Author(s)
      萩歩美、白髪恵美、石田竜弘、際田弘志
    • Organizer
      第23回日本DDS学会
    • Place of Presentation
      熊本
    • Year and Date
      2007-06-15
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] シクロフォスファミドを用いた low dose metronomic chemotherapy におけるドキソルビシン封入リポソームの併用効果および毒性の検討2007

    • Author(s)
      白髪恵美、石田竜弘、際田弘志
    • Organizer
      第16回DDSカンファランス
    • Place of Presentation
      静岡
    • Year and Date
      2007-07-14
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] シクロフォスファミドを用いたlow dose metronomic chemotherapy およびドキソルビシン封入リポソーム併用による抗腫瘍効果の検討2007

    • Author(s)
      白髪恵美、石田竜弘、際田弘志
    • Organizer
      日本薬剤学会第22年会
    • Place of Presentation
      大宮
    • Year and Date
      2007-05-23
    • Data Source
      KAKENHI-PROJECT-19790128
  • [Presentation] Intelligent RNA expressing device (iRed) を利用した核酸創薬の新手法

    • Author(s)
      田良島典子,小島孝光,金城望,古川和寛、安藤英紀,石田竜弘,南川典昭
    • Organizer
      第32回メディシナルケミストリーシンポジウム
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2014-11-26 – 2014-11-28
    • Data Source
      KAKENHI-PROJECT-24390027
  • [Presentation] Intelligent RNA expression device (iRed) を利用した 新規遺伝子発現抑制法の開発

    • Author(s)
      田良島 典子, 小島 孝允, 金城 望, 古川 和寛, 安藤 英紀, 石田 竜弘, 南川 典昭
    • Organizer
      第95回日本化学会
    • Place of Presentation
      日本大学 船橋キャンパス(千葉県船橋市)
    • Year and Date
      2015-03-26 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-24390027
  • 1.  KIWADA Hiroshi (50120184)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 75 results
  • 2.  清水 太郎 (30749388)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 18 results
  • 3.  ISHIMA Yu (00457590)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 33 results
  • 4.  安藤 英紀 (00735524)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 15 results
  • 5.  MINAKAWA Noriaki (40209820)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 6.  小田切 優樹 (80120145)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 22 results
  • 7.  KATAOKA Masaroshi (20224438)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SHINOHARA Yasuo (60226157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORI Shuji (50220009)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  佐塚 泰之 (90162403)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  山崎 尚志 (20271083)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  鵜川 真実 (50735511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 13.  阿部 洋 (80415067)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  中村 嘉利 (20172455)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  森脇 真希 (10444192)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  浅田 元子 (10580954)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  中崎 清彦 (70180263)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  岡田 直人 (30623269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  田島 健次 (00271643)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 20.  佐藤 敏文 (80291235)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  磯野 拓也 (70740075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  甲野 裕之 (70455096)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  藤田 彩華 (90782011)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  奥平 桂一郎 (10425671)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 25.  田中 将史 (40411904)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  小出 裕之 (60729177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  EMAM SHERIF
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  WATANABE Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 6 results
  • 29.  MARUYAMA Toru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 7 results
  • 30.  KOGA Tomoaki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 31.  FUJIWARA Yukio
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 32.  WATANABE Takehisa
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 33.  関 貴弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 34.  香月 博志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 35.  赤池 孝章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 36.  森岡 弘志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 37.  田良島 典子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 38.  古川 和寛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 39.  竹屋 元裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 40.  佐々木 裕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  國安 明彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  小橋川 敬博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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