Shimizu Taro 清水太郎

… Alternative Names

SHIMIZU Taro 清水太郎

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Researcher Number	30749388
Other IDs
Affiliation (Current)	2025: 大阪大学, 微生物病研究所, 特任講師(常勤)
Affiliation (based on the past Project Information) *help	2023 – 2024: 大阪大学, 微生物病研究所, 特任講師(常勤) 2018 – 2023: 徳島大学, 大学院医歯薬学研究部(薬学域), 特任助教 2016 – 2017: 徳島大学, 大学院医歯薬学研究部(薬学系), 特任助教 2015: 徳島大学, 大学院医歯薬学研究部, 特任助教
Review Section/Research Field	Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Medical pharmacy / Basic Section 90120:Biomaterials-related / Transformative Research Areas, Section (II) / Basic Section 47060:Clinical pharmacy-related Except Principal Investigator Medium-sized Section 90:Biomedical engineering and related fields / Physical pharmacy / Basic Section 90120:Biomaterials-related / Basic Section 47060:Clinical pharmacy-related / Basic Section 59040:Nutrition science and health science-related
Keywords	Principal Investigator ナノ粒子 / 免疫細胞 / 薬物送達 / 免疫学 / 癌 / 辺縁帯B細胞 / ワクチン / IgA / 経鼻投与 / アルブミン … More / ターゲティング / リンパ節 / 抗原提示細胞 / 脂質ナノ粒子 / mRNAワクチン / 遊走 / 脳腫瘍 / 寛容 / 抗体 / B細胞 / 人工高分子 / 核酸 / 物質共生 / 免疫複合体 / 自己抗体 / SLE / 脾臓免疫細胞 / プロテオーム解析 / 自己抗原 / マイクロパーティクル / 自己免疫疾患 / 全身性エリテマトーデス / 外部刺激 / がん化学療法 / 癌免疫療法 / 細胞送達 / がん免疫療法 / .細胞送達 / 養子移入療法 / がん / リポソーム / 補体 / 抗原送達 … More Except Principal Investigator CARPA / infusion reaction / 抗PEG抗体 / PEG修飾製剤 / イオン液体 / ワクチン / DDS / リポソーム / 吸収改善 / 中分子医薬品 / 結合性評価 / ポリクローナル抗体 / 膜タンパク抗体 / 抗血清 / エキソソーム / 膜タンパク / 抗体誘導 / 脾臓免疫 / エクソソーム / アポリポタンタンパク質 / アポリポタンパク質 / 高密度リポ蛋白質 / 高密度リポタンパク質 / 動脈硬化 / ペプチド / 経皮吸収 / ナノキャリア / アジュバント / 自然免疫活性化 / 核酸デリバリー / Anti-PEG IgM / 免疫 / 核酸 Less

Creation of mRNA-LNP vaccine targeting to antigen presenting cellsPrincipal Investigator
- Principal Investigator
  
  清水太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Osaka University
Development of intranasal vaccine using albumin-based nanoparticlesPrincipal Investigator
- Principal Investigator
  
  清水太郎
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Osaka University
人工高分子PEGに対する生体防御反応の解明と統合的理解
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  The University of Tokushima
イオン液体を用いた中分子医薬品の革新的・非侵襲的吸収促進技術の開発
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
Treatment of glioblastoma with immune cells loaded with anticancer therapeuticsPrincipal Investigator
- Principal Investigator
  
  Shimizu Taro
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Osaka University
  The University of Tokushima
物質共生のための人工物質とＢ細胞の相互作用解析と免疫応答評価Principal Investigator
- Principal Investigator
  
  清水太郎
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokushima
Establishment of a spleen immunization technology platform using exosomes to induce antibodies that can recognize the membrane proteins of host cells.
- Principal Investigator
  
  ANDO Hidenori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  The University of Tokushima
Functional analysis of ApoA-I/HDL binding protein for the treatment of atherosclerosis
- Principal Investigator
  
  Okuhira Keiichiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Osaka Medical and Pharmaceutical University
  Osaka University of Pharmaceutical Sciences
Investigation on the role of microparticles on the pathogenesis of systemic lupus erythematosusPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Taro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  The University of Tokushima
PEG修飾タンパクによるアナフィラキシー誘導機構の解明とその制御に関する研究
- Principal Investigator
  
  石田竜弘
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
Development of transdermal drug delivery system by ionic liquid
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
Development of cell-based intratumor drug delivery using immune cellsPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Taro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
Development of nover antigen delivery system for tumor therapy
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima
Development of a novel cancer vaccine utilizing liposomes modified with complement activation polymerPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Taro
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  The University of Tokushima
Study of immunological response to nucleic acid delivery system
- Principal Investigator
  
  ISHIDA Tatsuhiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  The University of Tokushima

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route2023
- Author(s)
  Takata Haruka、Shimizu Taro、Yamade Rina、Elsadek Nehal E.、Emam Sherif E.、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 360 Pages: 285-292
- DOI
  10.1016/j.jconrel.2023.06.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279, KAKENHI-PROJECT-22KJ2352, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-23K28428
[Journal Article] Investigation of anti-PEG antibody response to PEG-containing cosmetic products in mice2023
- Author(s)
  Ibrahim Mohamed、Shimizu Taro、Ando Hidenori、Ishima Yu、Elgarhy Omar Helmy、Sarhan Hatem A.、Hussein Amal K.、Ishida Tatsuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 354 Pages: 260-267
- DOI
  10.1016/j.jconrel.2023.01.012
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279, KAKENHI-PUBLICLY-21H05526, KAKENHI-PROJECT-23K28428
[Journal Article] Ionic Liquid-Based Transcutaneous Peptide Antitumor Vaccine: Therapeutic Effect in a Mouse Tumor Model2023
- Author(s)
  Shimizu Taro、Matsuzaki Takaaki、Fukuda Shoichiro、Yoshioka Chihiro、Shimazaki Yuna、Takese Shunsuke、Yamanaka Katsuhiro、Nakae Takashi、Ishibashi Masaki、Hamamoto Hidetoshi、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
- Journal Title
  
  The AAPS Journal
  
  Volume: 25 Issue: 2 Pages: 27-27
- DOI
  10.1208/s12248-023-00790-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K17477
[Journal Article] FTY720 Reduces Lipid Accumulation by Upregulating ABCA1 through Liver X Receptor and Sphingosine Kinase 2 Signaling in Macrophages2022
- Author(s)
  Tachibana Koki、Kusumoto Kohshi、Ogawa Mai、Ando Hidenori、Shimizu Taro、Ishima Yu、Ishida Tatsuhiro、Okuhira Keiichiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 23 Pages: 14617-14617
- DOI
  10.3390/ijms232314617
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04124, KAKENHI-PROJECT-22KJ2355, KAKENHI-PROJECT-16KK0203
[Journal Article] Using Bio-Layer Interferometry to Evaluate Anti-PEG Antibody-Mediated Complement Activation2022
- Author(s)
  Mahmoud Mostafa, Nehal E. Elsadek, Sherif E. Emam, Hidenori Ando, Taro Shimizu, Hamdy Abdelkader, Yu Ishima, Usama Farghaly Aly, Hatem A. Sarhan, Tatsuhiro Ishida
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 1 Pages: 129-135
- DOI
  10.1248/bpb.b21-00772
- NAID
  130008139073
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-01-01
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05526, KAKENHI-PROJECT-19KK0279
[Journal Article] Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products2022
- Author(s)
  Ibrahim Mohamed、Ramadan Eslam、Elsadek Nehal E.、Emam Sherif E.、Shimizu Taro、Ando Hidenori、Ishima Yu、Elgarhy Omar Helmy、Sarhan Hatem A.、Hussein Amal K.、Ishida Tatsuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 351 Pages: 215-230
- DOI
  10.1016/j.jconrel.2022.09.031
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279, KAKENHI-PUBLICLY-21H05526
[Journal Article] A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes2022
- Author(s)
  Marwa M. El Sayed, Taro Shimizu, Amr S. Abu Lila, Nehal E. Elsadek, Sherif E. Emam, Eman Alaaeldin, Amal Kamal, Hatem A. Sarhan, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 615 Pages: 121539-121539
- DOI
  10.1016/j.ijpharm.2022.121539
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07194, KAKENHI-PUBLICLY-21H05526, KAKENHI-PROJECT-19KK0279, KAKENHI-PROJECT-21H02645
[Journal Article] Reduction-responsive and multi-drug deliverable albumin nanoparticles: an antitumor drug to Abraxane_ against human pancreatic tumor-bearing mice2021
- Author(s)
  Naoki Hirakawa, Yu Ishima, Ryo Kinoshita, Ryuto Nakano, Victor Tuan Giam Chuang, Hidenori Ando, Taro Shimizu, Keiichiro Okuhira, Toru Maruyama, Masaki Otagiri, Tatsuhiro Ishida
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 268 Issue: 5 Pages: 4302-4309
- DOI
  10.1021/acsabm.1c00110
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21485, KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20H04124, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-21K19716
[Journal Article] Nucleic acids delivered by PEGylated cationic liposomes in systemic lupus erythematosus-prone mice: a possible exacerbation of lupus nephritis in the presence of pre-existing anti-nucleic acid antibodies2021
- Author(s)
  Takata Haruka、Shimizu Taro、Kawaguchi Yoshino、Ueda Hiro、Elsadek Nehal E.、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: - Pages: 120529-120529
- DOI
  10.1016/j.ijpharm.2021.120529
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07194, KAKENHI-PROJECT-19KK0279, KAKENHI-PROJECT-22KJ2352
[Journal Article] Incorporating Gangliosides into PEGylated Cationic Liposomes that Complexed DNA Attenuates Anti-PEG Antibody Production but Not Anti-DNA Antibody Production in Mice2021
- Author(s)
  Milad Reda Qelliny, Taro Shimizu, Nehal E. Elsadek, Sherif E. Emam, Haruka Takata, Zeinab M. A. Fathalla, Amal K. Hussein, Khaled A. Khaled, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida
- Journal Title
  
  Molecular Pharmaceutics
  
  Volume: 18 Issue: 6 Pages: 2406-2415
- DOI
  10.1021/acs.molpharmaceut.1c00255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07194
[Journal Article] The Therapeutic Effect of Human Serum Albumin Dimer-Doxorubicin Complex against Human Pancreatic Tumors.2021
- Author(s)
  Kinoshita R, Ishima Y, Chuang VTG, Watanabe H, Shimizu T, Ando H, Okuhira K, Otagiri M, Ishida T, Maruyama T
- Journal Title
  
  Pharmaceutics.
  
  Volume: 13 Issue: 8 Pages: 1209-1209
- DOI
  10.3390/pharmaceutics13081209
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06810, KAKENHI-PROJECT-20H04124, KAKENHI-PROJECT-21H02645, KAKENHI-PROJECT-21K19716
[Journal Article] Complement activation induced by PEG enhances humoral immune responses against antigens encapsulated in PEG-modified liposomes2021
- Author(s)
  Shimizu Taro、Awata Mizuki、Abu Lila Amr S.、Yoshioka Chihiro、Kawaguchi Yoshino、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 329 Pages: 1046-1053
- DOI
  10.1016/j.jconrel.2020.10.033
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279
[Journal Article] Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon.2020
- Author(s)
  El Sayed, M.M., Takata, H., Shimizu, T., Kawaguchi, Y., Abu Lila, A.S., Elsadek, N.E., Alaaeldin, E., Ishima, Y., Ando, H., Kamal, A., Sarhan, H.A., Ishida, T.
- Journal Title
  
  J. Conrol. Release
  
  Volume: 323 Pages: 102-109
- DOI
  10.1016/j.jconrel.2020.04.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279, KAKENHI-PROJECT-18H02587
[Journal Article] Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice2020
- Author(s)
  Elsadek Nehal E.、Abu Lila Amr S.、Emam Sherif E.、Shimizu Taro、Takata Haruka、Ando Hidenori、Ishima Yu、Ishida Tatsuhiro
- Journal Title
  
  European Journal of Pharmaceutics and Biopharmaceutics
  
  Volume: 152 Pages: 56-62
- DOI
  10.1016/j.ejpb.2020.04.026
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0279
[Journal Article] Intratumoral visualization of oxaliplatin within a liposomal formulation using X-ray fluorescence spectrometry.2018
- Author(s)
  5.Ando, H., Abu Lila, A.S., Tanaka, M., Doi, Y., Terada, Y., Yagi, N., Shimizu, T., Okuhira, K., Ishima, Y., Ishida, T.,
- Journal Title
  
  Mol Pharm.
  
  Volume: 15 Issue: 2 Pages: 403-409
- DOI
  10.1021/acs.molpharmaceut.7b00762
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639, KAKENHI-PROJECT-16K08236
[Journal Article] Reactivity of IgM antibodies elicited by PEGylated liposomes or PEGylated lipoplexes against auto and foreign antigens.2018
- Author(s)
  8.Ando, H., Abu Lila, A.S., Kawanishi, M., Shimizu, T., Okuhira, K., Ishima, Y., Ishida, T.
- Journal Title
  
  J. Control Release
  
  Volume: 270 Pages: 114-119
- DOI
  10.1016/j.jconrel.2017.12.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639, KAKENHI-PROJECT-16K15108, KAKENHI-PROJECT-16K08236
[Journal Article] Modulation of antitumor immunity contributes to the enhanced therapeutic efficacy of liposomal oxaliplatin in mouse model.2017
- Author(s)
  11.Shimizu, T., Abu Lila, A.S., Nishio, M., Doi, Y., Ando, H., Ukawa, M., Ishima, Y., Ishida, T.
- Journal Title
  
  Cancer Sci.
  
  Volume: 108 Issue: 9 Pages: 1864-1869
- DOI
  10.1111/cas.13305
- NAID
  120006535002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Journal Article] Ganglioside inserted into PEGylated liposome attenuates anti-PEG immunity.2017
- Author(s)
  Mima, Y., Abu Lila, A.S., Shimizu, T., Ukawa, M., Ando, H., Kurata, Y., Ishida, T.
- Journal Title
  
  J. Control. Release
  
  Volume: 250 Pages: 20-26
- DOI
  10.1016/j.jconrel.2017.01.040
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] ドキソルビシン封入リポソーム搭載脾臓細胞による抗腫瘍効果の検討2023
- Author(s)
  松木佑樹、清水太郎、安藤英紀、異島優、石田竜弘
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K19897
[Presentation] イオン液体による難吸収性中分子化合物の腸管吸収促進効果の検討2023
- Author(s)
  福田翔一郎、安藤英紀、中江崇、辰巳昇、濱本英利、清水太郎、異島優、石田竜弘
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23K17477
[Presentation] Role of B cells in antitumor immune responses induced by antigen-loaded hydroxyl PEG-modified liposomes.2023
- Author(s)
  Shimizu, T., Kawaguchi, Y., Ishida, T.
- Organizer
  16th International Symposium on Nanomedicine
- Invited
- Data Source
  KAKENHI-PROJECT-23K28428
[Presentation] 化粧水塗布時の含有PEGの皮膚透過と抗PEG IgM誘導に関する検討2023
- Author(s)
  Mohamed Ibrahim、清水太郎、安藤英紀、異島優、石田竜弘
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-19KK0279
[Presentation] 化粧水の塗布による抗PEG IgMの誘導が抗がん剤封入PEG修飾リポソームの抗腫瘍効果に与える影響2023
- Author(s)
  石田竜弘、Sherif Armia、清水太郎、安藤英紀、異島優
- Organizer
  第39回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-23K28428
[Presentation] Impact of pre-existing anti-PEG IgM on the mRNA/LNP i.m. vaccination.2023
- Author(s)
  Takata, H., Abe, S., Shimizu, T., Ando, H., Ishida, T.
- Organizer
  16th International Symposium on Nanomedicine
- Invited
- Data Source
  KAKENHI-PROJECT-23K28428
[Presentation] 核酸搭載リポソームの物理化学的性質が抗核酸抗体の誘導に与える影響の検討2022
- Author(s)
  上田大、清水太郎、安藤英紀、異島優、山吉麻子、石田竜弘
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-19KK0279
[Presentation] mRNA封入脂質ナノ粒子構成成分のPEGに対する抗PEG抗体の誘導及びアナフィラキシー様反応への影響2022
- Author(s)
  阿部舜史、高田春風、安藤英紀、清水太郎、異島優、石田竜弘
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] 緑色蛍光タンパク質（EGFP）をモデル抗原として封入したPEG修飾エクソソームの脾臓送達による抗原特異的抗体の誘導2022
- Author(s)
  倉本伶音、安藤英紀、清水太郎、異島優、石田竜弘
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02644
[Presentation] 血中の抗PEG抗体が筋肉内投与後のmRNA搭載LNPのタンパク質発現に与える影響に関する検討2022
- Author(s)
  阿部舜史、高田春風、清水太郎、安藤英紀、異島優、石田竜弘
- Organizer
  遺伝子・デリバリー研究会第20回夏期セミナー
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] ガングリオシドを用いた抗核酸抗体誘導抑制効果の検討2022
- Author(s)
  高田春風、Milad Qelliny、清水太郎、上田大、安藤英紀、異島優、石田竜弘
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] 抗原とオボアルブミンを共封入したPEG修飾リポソームの脾臓送達による抗原特異的抗体誘導の増強効果2022
- Author(s)
  山本舜人、安藤英紀、清水太郎、異島優、石田竜弘
- Organizer
  第38回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0279
[Presentation] siRNA搭載PEG修飾リポソームの投与経路がおよぼす抗PEG抗体誘導への影響に関する検討2022
- Author(s)
  高田春風、清水太郎、上田大、安藤英紀、異島優、石田竜弘
- Organizer
  遺伝子・デリバリー研究会第20回夏期セミナー
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] 核酸搭載PEG修飾脂質ナノ粒子に対する免疫応答評価とその制御2022
- Author(s)
  清水太郎、石田竜弘
- Organizer
  日本薬剤学会第3回超分子薬剤学FGシンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] PEG修飾リポソームの投与経路がおよぼす抗PEG抗体誘導への影響に関する検討2022
- Author(s)
  高田春風、清水太郎、安藤英紀、異島優、石田竜弘
- Organizer
  第43回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] デキサメタゾンが及ぼすPEG修飾ナノ粒子による抗PEG抗体誘導への影響2022
- Author(s)
  高田春風、清水太郎、阿部舜史、安藤英紀、異島優、石田竜弘
- Organizer
  第16回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] mRNA搭載LNP構成成分のPEG脂質が示す免疫原性及びアナフィラキシー様反応への影響2022
- Author(s)
  阿部舜史、高田春風、清水太郎、安藤英紀、異島優、石田竜弘
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] 核酸搭載リポソームの物理化学的性質が抗核酸抗体の誘導に与える影響の検討2022
- Author(s)
  上田大、清水太郎、安藤英紀、異島優、山吉麻子、石田竜弘
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] エクソソームの脾臓免疫で得た抗血清（ポリクローナル抗体）の結合性評価2021
- Author(s)
  倉本伶音、安藤英紀、清水太郎、異島優、石田竜弘
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-21H02644
[Presentation] Evaluation of immunogenicity and adverse effects of nucleic acid-loaded nanoparticles2021
- Author(s)
  清水太郎, 高田春風, Qelliny Reda Milad, 石田竜弘
- Organizer
  14th International Symposium on Nanomedicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07194
[Presentation] 全身性エリテマトーデスモデルマウス由来マイクロパーティクルにおけるプロテオーム解析2021
- Author(s)
  上田大, 髙田春風, 清水太郎, 安藤英紀, 異島優, 石田竜弘
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-19K07194
[Presentation] 核酸搭載PEG修飾リポソームが全身性エリテマトーデスの発症時期，増悪に与える影響2021
- Author(s)
  髙田春風, 清水太郎, 安藤英紀, 異島優, 石田竜弘
- Organizer
  日本薬剤学会第36年会
- Data Source
  KAKENHI-PROJECT-19K07194
[Presentation] The induction level of anti-PEG IgM by PEGylated liposomes depends on the route of administration and the presence of nucleic acids2021
- Author(s)
  高田春風, 清水太郎, 上田大, 安藤英紀, 異島優, 石田竜弘
- Organizer
  14th International Symposium on Nanomedicine
- Data Source
  KAKENHI-PUBLICLY-21H05526
[Presentation] 核酸搭載PEG修飾カチオン性リポソームによる抗PEG抗体および抗核酸抗体誘導に及ぼすガングリオシド修飾の影響2021
- Author(s)
  清水太郎, Qelliny Milad, 高田春風, 上田大, 安藤英紀, 異島優, 石田竜弘
- Organizer
  第60回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-19K07194
[Presentation] タンパクのPEG修飾による抗PEG免疫応答の誘導2019
- Author(s)
  清水太郎, 異島優, 石田竜弘
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K15505
[Presentation] マイクロパーティクルによる抗体産生誘導は全身性エリテマトーデスの症状進行に関与する2019
- Author(s)
  上田大, 高田春風, 清水太郎, 安藤英紀, 異島優, 石田竜弘
- Organizer
  第35回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07194
[Presentation] イオン液体を用いた新規インスリン含有経皮吸収製剤は糖尿病治療薬になりうる2019
- Author(s)
  佐々井雅樹、清水太郎、奥平桂一郎、異島優、石橋賢樹、三輪泰司、濱本英利、石田竜弘
- Organizer
  第28回DDSカンファランス（静岡、グランシップ）
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] 全身性エリテマトーデス病態時の脾臓免疫細胞によるマイクロパーティクルの取り込み変化の検討2019
- Author(s)
  上田大, 高田春風, 清水太郎, 安藤英紀, 異島優, 石田竜弘
- Organizer
  第58回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-19K07194
[Presentation] Doxil前処置による養子免疫細胞のがん移行性向上に関する検討2018
- Author(s)
  中見祥一, 清水太郎, 異島優, 石田竜弘
- Organizer
  第57回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Data Source
  KAKENHI-PROJECT-17K15505
[Presentation] Immunological responses against PEGylated liposomes: the application of ABC phenomenon into cancer vaccine.2018
- Author(s)
  Ishida, T., Shimizu, T.
- Organizer
  12th International Symposium on Nanomedicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K19925
[Presentation] Development of marginal zone B cell-targeted cancer vaccine2018
- Author(s)
  Taro Shimizu
- Organizer
  第6回日中ナノメディシンシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15505
[Presentation] 補体活性化能を持つポリマー修飾リポソームによる脾臓辺縁帯B細胞標的化に関する検討2017
- Author(s)
  清水太郎、粟田瑞月、吉岡千尋、異島優、石田竜弘
- Organizer
  日本薬剤学会第32年会
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] 脾臓辺縁帯B細胞標的化能をもつポリマー修飾リポソームを用いた静注型ワクチン開発に関する検討2017
- Author(s)
  吉岡千尋、粟田瑞月、渡辺優希、清水太郎、石田竜弘
- Organizer
  第33回日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] 脾臓辺縁帯B細胞標的化能をもつポリマー修飾リポソームの探索2016
- Author(s)
  粟田瑞希, 吉岡千尋, 渡辺優希, 清水太郎, 石田竜弘
- Organizer
  第32回日本DDS学会学術集会
- Place of Presentation
  静岡県コンベンションアーツセンター（静岡県静岡市）
- Year and Date
  2016-06-30
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] リポソーム化抗がん剤投与が引き起こす腫瘍免疫細胞の影響2016
- Author(s)
  高山拓磨、清水太郎、鵜川真実、石田竜弘
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] Liposomal oxaliplatin has superior immunomodulation effect to free oxaliplatin on tumor immune microenvironment2016
- Author(s)
  Taro Shimizu, Tatsuhiro Ishida
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県宜野湾市）
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] PEG修飾有機シリカ粒子に対する免疫応答に関する検討2016
- Author(s)
  中見祥一、清水太郎、中村教泰、石田竜弘
- Organizer
  第５５回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  就実大学薬学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] ポリエチレングリコール修飾タンパク製剤Pegasysに対する抗PEG IgM応答2016
- Author(s)
  本藤栄里、美馬優、清水太郎、石田竜弘
- Organizer
  日本薬学会第１３６年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] Development of a unique vaccine by using immune response against intravenously injected PEGylated liposomes2016
- Author(s)
  Taro Shimizu
- Organizer
  Seminars in Nanomedicine
- Place of Presentation
  ブダペスト（ハンガリー）
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] PEG修飾リポソームのPEG末端構造ががんワクチン効果に与える影響2016
- Author(s)
  吉岡千尋, 粟田瑞月, 渡辺優希, 清水太郎, 石田竜弘
- Organizer
  ナノライフサイエンス・オープンセミナー2015
- Place of Presentation
  サンライズ淡路（兵庫県南あわじ市）
- Year and Date
  2016-02-20
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] PEGリポソームへのアルブミン修飾は、抗PEG抗体の産生を抑制する2016
- Author(s)
  山﨑仁王、異島優、清水太郎、石田竜弘
- Organizer
  第５５回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  就実大学薬学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] 脾臓辺縁帯B細胞を標的としたワクチンによる新規がん治療法の開発2016
- Author(s)
  清水太郎
- Organizer
  第41回製剤・創剤セミナー
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2016-08-25
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] ヒトにおける抗PEG抗体保有率の調査2016
- Author(s)
  清水太郎、久保幸代、石田竜弘
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場・岐阜都ホテル（岐阜県・岐阜市）
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] 抗がん剤封入リポソームとの併用によるがんワクチン効果の増強に関する検討2016
- Author(s)
  竹瀬俊輔、高山拓磨、西尾美穂、清水太郎、石田竜弘
- Organizer
  第５５回日本薬学会・日本薬剤師会・日本病院薬剤師会　中国四国支部学術大会
- Place of Presentation
  就実大学薬学部（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-16K15108
[Presentation] 脾臓辺縁帯B細胞を標的としたリポソームワクチンの開発2016
- Author(s)
  清水太郎, 渡辺優希, 美馬優, 際田弘志, 石田竜弘
- Organizer
  第25回DDSカンファランス
- Place of Presentation
  静岡県コンベンションアーツセンター（静岡県静岡市）
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] IV 投与PEGリポソームに対するanti-PEG IgM応答への腹腔内免疫細胞の関与2015
- Author(s)
  阿部遼、清水太郎、石田竜弘
- Organizer
  日本薬剤学会第３０年会
- Place of Presentation
  長崎ブリックホール（長崎県長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] Altering PEGylated liposomes modification from DSPE-PEG-OCH3 to DSPE-PEG-OH suppresses secretion of anti-PEG IgM and proliferation of PEG-specific B cell2015
- Author(s)
  Mizuki Awata, Risako Fujita, Yu Mima, Munehira Kawanishi, Taro Shimizu, Tatsuhiro Ishida
- Organizer
  Liposome Advances 2015
- Place of Presentation
  UCL School of Pharmacy（ロンドン、イギリス）
- Year and Date
  2015-12-19
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] PEG化製剤に対するanti-PEG IgM結合特性に関する検討2015
- Author(s)
  久保幸代、本藤栄里、阿部遼、美馬優、清水太郎、石田竜弘
- Organizer
  第５４回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知テルサ（高知県高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15H04639
[Presentation] FTY720併用によるドキシルの細胞内取り込み向上に関する検討2015
- Author(s)
  清水太郎, 高橋孝典, 石田竜弘
- Organizer
  第37回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  熊本大学薬学部（熊本県熊本市）
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] 脾臓辺縁帯B細胞を標的とした新規がんワクチンの開発2015
- Author(s)
  清水太郎, 渡辺優希, 美馬優, 際田弘志, 石田竜弘
- Organizer
  第4回若手研究者シーズ発表会
- Place of Presentation
  県立広島大学サテライトキャンパスひろしま（広島県広島市）
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-15K18921
[Presentation] ヒドロキシ末端PEG修飾リポソームを用いた静注型ワクチン開発に関する基礎的検討2015
- Author(s)
  吉岡千尋, 粟田瑞月, 渡辺優希, 清水太郎, 石田竜弘
- Organizer
  第54回日本薬学会・日本薬剤師会・日本病院薬剤師会中国四国支部学術大会
- Place of Presentation
  高知市文化プラザかるぽーと（高知県高知市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-15K18921

1. ISHIDA Tatsuhiro (50325271)

# of Collaborated Projects: 9 results

# of Collaborated Products: 34 results
2. ANDO Hidenori (00735524)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
3. 異島優 (00457590)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. Okuhira Keiichiro (10425671)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 南川典昭 (40209820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 鵜川真実 (50735511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. 岡田直人 (30623269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 田中将史 (40411904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小出裕之 (60729177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 高田春風 (10986714)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MARUYAMA Toru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 小田切優樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimizu Taro 清水 太郎

SHIMIZU Taro 清水 太郎

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Creation of mRNA-LNP vaccine targeting to antigen presenting cellsPrincipal Investigator

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Development of intranasal vaccine using albumin-based nanoparticlesPrincipal Investigator

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Treatment of glioblastoma with immune cells loaded with anticancer therapeuticsPrincipal Investigator

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物質共生のための人工物質とＢ細胞の相互作用解析と免疫応答評価Principal Investigator

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Investigation on the role of microparticles on the pathogenesis of systemic lupus erythematosusPrincipal Investigator

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Development of cell-based intratumor drug delivery using immune cellsPrincipal Investigator

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Development of a novel cancer vaccine utilizing liposomes modified with complement activation polymerPrincipal Investigator

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Shimizu Taro 清水太郎

SHIMIZU Taro 清水太郎