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KOMORI atsumasa  小森 敦正

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KOMORI Atsumasa  小森 敦正

小森 敦正  コモリ アツマサ

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Researcher Number 50234901
Other IDs
Affiliation (Current) 2025: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 臨床研究センター, 難治性疾患研究部長
Affiliation (based on the past Project Information) *help 2013: 独立行政法人国立病院機構長崎医療センター臨床研究センター, 部長
2010: 独立行政法人国立病院機構長崎医療センター, 臨床研究センター, 室長
2009 – 2010: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 室長
2008: 長崎医療センター, 臨床研究センター, 再生医療研究室長
2008: 長崎医療センター, 臨床研究センター, 病態制御研究室長 … More
2007: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 病態制御研究部, 室長
2006: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 再生医療研究室, 室長
2006: Nagasaki Medical Center, Clinical Research Center, Division Chief of Regererative medicine, 臨床研究センター・再生医療研究部, 室長
2005: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 再生医療研究室長
2005: 独立行政法人国立病院機構(長崎医療センター臨床研究センター), 先端技術研究部, ウイルス研究室
2005: Clinical Research Center, Nagasaki Medical Center, 臨床研究センター, 再生医療研究部長
2004: 独立行政法人国立病院機構長崎医療センター, 臨床研究センター, ウイルス研究室長
2003: 国立病院, 長崎医療センター・臨床研究センター, ウイルス研究室長
1996: 埼玉県立がんセンター, 研究所・血清ウイルス部, 研究員
1994 – 1995: 埼玉県立がんセンター, 研究所 血清ウイルス部, 研究員 Less
Review Section/Research Field
Except Principal Investigator
Gastroenterology / Human pathology
Keywords
Except Principal Investigator
原発性胆汁性肝硬変 / 抗gp210抗体 / NHOSLJ / primary biliary cirrhosis / 抗ミトコンドリア抗体 / 自然免疫 / 胆管上皮細胞 / 予後予測マーカー / 抗セントロメア抗体 / anti-nuclear antibodies … More / anti-mitochondrial antibodies / predictive autoantibodies / anti-centromere antibodies / anti-gp210 antibodies / TLR3 / centromere / gp210 / 分子標的 / 抗核抗体 / 予後予測抗体 / anti-mitochondrial antibody / prediction of prognosis / anti-gp210 antibody / Toll-like receptor (TLR) / innate immunity / biliary epithelial cells / bile duct damage / 病因関連抗原 / CD8陽性T細胞 / 自己反応性T細胞 / ミトコンドリア抗体 / 予後予測因子 / 抗原特異的T細胞 / ミトコンドリア抗原 / PPARα / Toll-like受容体 / 胆管障害 / 疾患発症パスウェイ / 全ゲノム関連解析 / 肝臓学 / GWAS / 疾患感受性遺伝子 / 長期予後診断 / 非黄疸型進行 / 黄疸型進行 / バイオマーカー / 予後 / HLA-DRB1 / 一塩基多型(SNP) / 病型分類 / HLA / 遺伝子多型 / SNPs / 予後予測 / 小児甲状腺がん / 放射線被爆 / BRAF / PTC / ret / チェルノブイリ / 小児甲状腺癌 / 放射線誘発腫瘍 / 遺伝子治療 / リボザイム / 転写因子 / MTG8 / 遺伝子融合 / AML1-MTG8 / t(8;21)転座型 / 白血病 / コードファクター / ノジュラリン / ミクロチスチン / tautomycin / transgenicマウス / TNF-αプロセシング / 発がん抑制物質 / protein phosphatase / 内因性発がんプロモーター / TPA / TNF-αトランスジェニックマウス / TNF-α / オカダ酸 Less
  • Research Projects

    (7 results)
  • Research Products

    (115 results)
  • Co-Researchers

    (16 People)
  •  Genome-wide associationstudy to detect disease-associated genes in Japanese patients with primary biliary cirrhosis

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  New clinical classification and the criteria for predicting long-term outcome in primary biliary cirrhosis

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Mechanisms of radiation-induced pediatric thyroid cancer

    • Principal Investigator
      ITO Masahiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Department of Clinical Research, National Hospital Organization Nagasaki Medical Center
  •  Identification of new molecular targets and the study for the mechanism of bile ducts-and hepatocyte-destruction in primary biliary cirrhosis

    • Principal Investigator
      NAKAMURA Minoru
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      National Hospital Organization(NHO) Nagasaki Medical Center
  •  Dissection of autoimmune response and establishment of diagnosis and treatment of primary biliary cirrhosis

    • Principal Investigator
      ISHIBASHI Hiromi
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Clinical Research Center National Hospital Organization (NHO) Nagasaki Medical Center
  •  t(8;21)転座型白血病におけるMTG8遺伝子産物の機能と新しい治療法の開発

    • Principal Investigator
      神津 知子
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center
  •  TNF-αによる発がんプロモーションとその阻害

    • Principal Investigator
      藤木 博太
    • Project Period (FY)
      1994 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Research Institute for Clinical Oncology, Saitama Cancer Center

All 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Other

All Journal Article Presentation Book

  • [Book] HLADRB1遺伝子多型が降格抗体による原発性胆汁性肝硬変の予後予測に及ぼす影響の検討,消化器と免疫N046, 20092010

    • Author(s)
      中村稔、安波道郎、近藤久義、相葉佳洋、小森敦正、長岡進矢、阿比留正剛、八橋弘、右田清志、石橋大海
    • Publisher
      マイライフ社
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] 日本人原発性胆汁性肝硬変患者(PBC)のCTLA4一塩基多型(SNP)の解析.消化器と免疫N046, 20092010

    • Author(s)
      相葉佳洋、小森敦正、右田清志、八橋弘、塚元和弘、石橋大海、中村稔
    • Publisher
      マイライフ社
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Book] Annual Review消化器 : 原発性胆汁性肝硬変 (PBC)2007

    • Author(s)
      石橋大海, 小森敦正, 中村 稔
    • Publisher
      中外医学社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Book] Annual Review 消化器:原発性胆汁性肝硬変(PBC)2007

    • Author(s)
      石橋大海, 小森敦正, 中村 稔
    • Publisher
      中外医学社
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Book] 肝疾患と免疫(各務伸一編)2006

    • Author(s)
      小森敦正, 中村稔, 石橋大海
    • Total Pages
      179
    • Publisher
      医薬ジャーナル社
    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Book] 肝疾患と免疫(各務伸一 編)2005

    • Author(s)
      小森敦正, 中村稔, 石橋大海
    • Publisher
      医歯薬ジャーナル社
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients.2014

    • Author(s)
      Ohishi Y, Nakamuta M, Ishikawa N, Saitoh O, Nakamura H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Fukushima N, Kohjima M, Yoshimoto T, Fukuizumi K, Ishibashi M, Nishino T, Shirabe K, Taketomi A, Maehara Y, Ishibashi H, Nakamura M; PBC Study Group of NHOSLJ.
    • Journal Title

      J Gastroenterol.

      Volume: 49 Issue: 2 Pages: 332-342

    • DOI

      10.1007/s00535-013-0795-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-26293181
  • [Journal Article] PBC Study Group of NHOSLJ, Nakamura M. Genetic polymorphisms of OCT-1 confer susceptibility to severe progression of primary biliary cirrhosis in Japanese patients2013

    • Author(s)
      Ohishi Y, Nakamuta M, Ishikawa N, Saitoh O, Nakamura H, Aiba Y, Komori K, Migita K, Yatsuhashi H, Fukushima N, Kohjima M, Yoshimoto T, Fukuizumi K, Ishibashi M, Nishino T, Shirabe K, Taketomi A, Maehara Y, Ishibashi H
    • Journal Title

      J Gastroenterol

      Volume: (Epub ahead of print)

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population2013

    • Author(s)
      Migita K, Nakamura M, Abiru S, Jiuchi Y, Nagaoka S, Komori A, Hashimoto S, Bekki S, Yamasaki K, Komatsu T, Shimada M, Kouno H, Hijioka T, Kohjima M, Nakamuta M, Kato M, Yoshizawa K, Ohta H, Nakamura Y, Takezaki E, Nishimura H, Sato T, Ario K, Hirashima N, Oohara Y, Naganuma A, Muro T, Sakai H, Mita E, Sugi K, Yamashita H, Makita F, Yatsuhashi H, Ishibashi H, Yasunami M
    • Journal Title

      PLoS One

      Volume: 8(8) Pages: 71382-71382

    • NAID

      120006986124

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Systemic and local expression levels of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis.2013

    • Author(s)
      Aiba Y, Harada K, Komori A, Ito M, Shimoda S, Nakamura H, Nagaoka S, Abiru S, Migita K, Ishibashi H, Nakanuma Y, Nishida N, Kawashima M, Tokunaga K, Yatsuhashi H, Nakamura M.
    • Journal Title

      Liver Int.

      Volume: 34 Issue: 5 Pages: 679-688

    • DOI

      10.1111/liv.12296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590393, KAKENHI-PROJECT-23591006, KAKENHI-PROJECT-25860576, KAKENHI-PROJECT-26293181, KAKENHI-PROJECT-26461012
  • [Journal Article] 特集:自己免疫性肝胆膵疾患の病態解明の進歩. 原発性胆汁性肝硬変患者におけるTL1AとDcR3の臨床学的意義2013

    • Author(s)
      相葉 佳洋, 小森 敦正, 長岡 進矢, 阿比留 正剛, 右田 清志, 伊東 正博, 石橋 大海, 八橋 弘, 中村 稔
    • Journal Title

      消化器と免疫

      Volume: 49 Pages: 15-17

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 原発性胆汁性肝硬変(PBC)の疾患感受性遺伝子による病態の解明.2013

    • Author(s)
      中村 稔、西田奈央、川嶋実苗、相葉佳洋、小森敦正、八橋 弘、徳永勝士. 国立病院機構肝ネットワークPBC研究班、 厚生労働省難治性疾患克服研究事業・難治性の肝胆膵疾患に関する調査研究班.
    • Journal Title

      第20回浜名湖シンポジウム記録集 ゲノム情報の臨床応用

      Volume: なし Pages: 74-78

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population.2013

    • Author(s)
      Migita K, Nakamura M, Abiru S, Jiuchi Y, Nagaoka S, Komori A, Hashimoto S, Bekki S, Yamasaki K, Komatsu T, Shimada M, Kouno H, Hijioka T, Kohjima M, Nakamuta M, Kato M, Yoshizawa K, Ohta H, Nakamura Y, Takezaki E, Nishimura H, Sato T, Ario K, Hirashima N,..., Yatsuhashi H, Ishibashi H, Yasunami M.
    • Journal Title

      PLoS One

      Volume: 22;8 Issue: 8 Pages: e71382-e71382

    • DOI

      10.1371/journal.pone.0071382

    • NAID

      120006986124

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] 原発性胆汁性肝硬変の予後2013

    • Author(s)
      小森敦正、石橋大海、中村 稔、八橋 弘
    • Journal Title

      肝胆膵

      Volume: 66 Pages: 455-461

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Genome-wide Association Study Identifies TNFSF15 and POU2AF1 as Susceptibility Loci for Primary Biliary Cirrhosis in the Japanese Population2012

    • Author(s)
      Nakamura M, Nishida N, Kawashima M, Aiba Y, Tanaka A, Yasunami M, Nakamura H, Komori A, Nakamuta M, Zeniya M, Hashimoto E, Ohira H, Yamamoto K, Onji M, Kaneko S, Honda M, Yamagiwa S, Nakao K, Ichida T, Takikawa H, Seike M, Umemura T, Ueno Y, Sakisaka S, Kikuchi K, Ebinuma H, Yamashiki N, Tamura S, Sugawara Y, Mori A, Yagi S, Shirabe K, Taketomi A, Arai K, Monoe K, Ichikawa T, Taniai M, Miyake Y, Kumagi T, Abe M, Yoshizawa K, Joshita S, Shimoda S, Honda K, Takahashi H, Hirano K, Takeyama Y, Harada K, Migita K, Ito M, Yatsuhashi H, Fukushima N, Ota H, Komatsu T, Saoshiro T, Ishida J, Kouno H, Kouno H, Yagura M, Kobayashi M, Muro T, Masaki N, Hirata K, Watanabe Y, Nakamura Y, Shimada M, Hirashima N, Komeda T, Sugi K, Koga M, Ario K, Takesaki E, Maehara Y, Uemoto S, Kokudo N, Tsubouchi H, Mizokami M, Nakanuma Y, Tokunaga K, Ishibashi H
    • Journal Title

      Am J Hum Genet

      Volume: 91(4) Pages: 721-728

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Serum amyloid A (SAA) induces pentraxin 3(PTX3) production in rheumatoid synoviocytes2012

    • Author(s)
      Satomura K, Torigoshi T, Koga T, Maeda Y, Izumi Y, Jiuchi Y, Miyashita T, Yamasaki S, Kawakami A, Aiba Y, Nakamura M, Komori A, Sato J, Ishibashi H, Motokawa S, Migita K
    • Journal Title

      Mod Rheumatol

      Volume: (Epub ahead of print)

    • NAID

      10031167663

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] the Japanese NHO-Liver -network study group. Hepatocellular carcinoma and survival in patients with autoimmune hepatitis (Japanese National Hospital Organization-autoimmune hepatitis prospective study)2012

    • Author(s)
      Migita K, Watanabe Y, Jiuchi Y, Nakamura Y, Saito A, Yagura M, Ohta H, Shimada M, Mita E, Hijioka T, Yamashita H, Takezaki E, Muro T, Sakai H, Nakamuta M, Abiru S, Komori A, Ito M, Yatsuhashi H, Nakamura M, Ishibashi H
    • Journal Title

      Liver Int

      Volume: 32 Pages: 837-844

    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Positive anti-gp210 antibodies is a significant risk factor for bile duct loss, hepatitis and poor biochemical response to ursodeoxycholic acid treatment that lead to more severe progression in Japanese patients with primary biliary cirrhosis.2011

    • Author(s)
      Nakamura M, Ito M, Kondo H, Yamamoto K, Ohira H, Zeniya M, Tanaka A, Hashimoto E, Honda M, Kaneko S, Ueno Y, Kikuchi K, Shimoda S, Komori A, Harada K, Sakisaka S, Takikawa H, Onji M, et al
    • Journal Title

      Hepatology 2011; 54, Supple 1208A-1209A.

      Volume: 54, Supple

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Risk factors and prediction of long-term outcome in primary biliary cirrhosis.2011

    • Author(s)
      Ishibashi H, Komori A, 下田慎治, Ambrosini YM, Gershwin ME, Nakamura M
    • Journal Title

      Intern Med 50

      Pages: 1-10

    • NAID

      130000413190

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Analysis of HLA-DRB1 polymorphisms in Japanese patients with primary biliary cirrhosis (PBC) : the HLA-DRB1 polymorphism determines the relative risk of antinuclear antibodies for disease progression in PBC.2011

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Horie H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Ito M, Shimoda S, Ishbiashi H, PBC Study Group in NHOSLJ.
    • Journal Title

      Hepatol Res 40

      Pages: 494-504

    • NAID

      10026392072

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Positive anti-gp210 antibodies is a risk factor for poor biochemical response to ursodeoxycholic acid treatment in Japanese patients with primary biliary cirrhosis.2011

    • Author(s)
      Nakamura M, Ito M, Yamamoto K, Zeniya M, Ohira H, Hashimoto E, Honda M, Kaneko S, Ueno Y, Kikuchi K, Onji M, Shimoda S, Takikawa H, Tanaka A, Komori A, Yatsuhashi H,et al
    • Journal Title

      J Hepatol 2011

      Volume: 54,Suppl No1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] PBCの予後予測:自己抗体を基盤に2011

    • Author(s)
      中村稔、相葉佳洋、小森敦正、下田慎治、石橋大海
    • Journal Title

      肝胆膵 62

      Pages: 707-714

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] A polymorphism in the integrin alfa V subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.2011

    • Author(s)
      Inamine T, Nakamura M, Kawauchi A, Shirakawa Y, Hashiguchi H, Aiba Y, Taketomi A, Shirabe K, Nakamuta M, Hayashi S, Saoshiro T, Komori A, Yatsuhashi H, Kondo S, Omagari K, etal
    • Journal Title

      J Gastroenterol

      Volume: 46 Pages: 676-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] Evaluation of risk factors for the development of cirrhosis in autoimmune hepatitis : Japanese NHO-AIH prospective study.2011

    • Author(s)
      Migita K, Watanabe Y, Jiuchi Y, Nakamura Y, Saito A, Yagura M, Morimoto H, Shimada M, Mita E, Hijioka T, Yamashita H, Takezaki E, Muro T, Sakai H, Nakamuta M, Abiru S, Yano K, Komori A, Yatsuhashi H, Nakamura M, Ishibashi H
    • Journal Title

      J Gastroenterol 46 Suppl 1

      Pages: 56-62

    • NAID

      10029030300

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Serum Baff and APRIL levels in patients with PBC.2011

    • Author(s)
      Migita K, Ilyassova B, Kovzel EF, Nersesov A, Maeda Y, Komori A, Ito M, Yano K, Yatsuhashi H, Ishibashi H, Nakamura M
    • Journal Title

      Clin Immunol 134

      Pages: 217-225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] A polymorphism in the integrin・V subunit gene affects the progression of primary biliary cirrhosis in Japanese patients.2011

    • Author(s)
      Inamine T, Nakamura M, Kawauchi A, Shirakawa Y, Hashiguchi H, Aiba Y, Taketomi A, Shirabe K, Nakamuta M, Hayashi S, Saoshiro T, Komori A, Yatsuhashi H, Kondo S, Omagari K, Maehara Y, Ishibashi H, Tsukamoto K, the PBC Study Group in NHOSLJ.
    • Journal Title

      J Gastroenterol 46

      Pages: 676-686

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] PBCの病態の多様性と治療ガイドライン2011

    • Author(s)
      石橋大海、下田慎治、小森敦正、中村稔
    • Journal Title

      肝胆膵 62

      Pages: 715-722

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Genetic polymorphisms of CTLA4 and SLC4A2 are differently associated with the pathogenesis of primary biliary cirrhosis in Japanese patients.2011

    • Author(s)
      Aiba Y, Nakamura M, Joshita S, Inamime T, Komori A, Yoshizawa K, Umemura T, Horie H, Migita K, Yatsuhashi H, Nakamuta M, Fukushima N, Saoshiro T, Hayashi S, Kouno et al
    • Journal Title

      J Gastroenterol 2011

      Volume: 46 Pages: 1203-1212

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Journal Article] The genetic polymorphisms of CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliary cirrhosis in Japanese patients2011

    • Author(s)
      Aiba Y, Nakamura M, Joshita S, Inamine T, Komori A, Yoshizawa K, et al
    • Journal Title

      J Gastroenterol

      Volume: May 19(In press)

    • NAID

      10030294477

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] The genetic polymorphisms of CTLA4 and SLC4A2 are differentially associated with the pathogenesis of primary biliarycirrhosis in Japanese patients.2011

    • Author(s)
      Aiba Y, Nakamura M, Joshita S, Inamime T, Komori A, Yoshizawa K, Umemura T, Migita K, Yatsuhashi H, Nakamuta M, Fukushima N, Saito A, Kouno H, Ota H, Muro T, Hayashi S, Watanabe Y, Nakamura Y, Komeda T, Shimada M, Tsukamoto K, Tanaka E, Ishibashi H, the PBC Study Group in NHOSLJ.
    • Journal Title

      J Gastroenterol Epub ahead of print

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] 自己免疫性胆管疾患の病態形成への自然免疫の関与2011

    • Author(s)
      小森敦正、中村稔、石橋大海
    • Journal Title

      肝胆膵 62

      Pages: 639-643

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] 原発性胆汁性肝硬変ガイドラインの作成2010

    • Author(s)
      石橋大海、小森敦正、中村稔、下田慎治
    • Journal Title

      肝胆膵 Vol.60, No9

      Pages: 257-264

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Liver architecture, cell function, and disease.2009

    • Author(s)
      Ishibashi H, Nakamura M, Komori A, Migita K,Shimoda S
    • Journal Title

      Semin immunopathol 31

      Pages: 399-409

    • NAID

      120006984110

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] <クリニカル・トピックス>原発性胆汁性肝硬変における抗gp210抗体の臨床的意義2008

    • Author(s)
      中村稔, 下田愼治, 小森敦正, 石橋大海
    • Journal Title

      BIO Clinica 23(12)

      Pages: 1136-1143

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Increased expression of toll-like- receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers.2008

    • Author(s)
      Nakamura M, Funami K, Komori A, Yokoyama T, Aiba Y, Araki A, Takii Y, Ito M, Matsuyama M, Koyabu M, Migita K, Taniguchi K, Fujioka H, Yatsuhashi H, Matsumoto M, Ishibashi H, Seya T
    • Journal Title

      Hepatol Int 2

      Pages: 222-230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Increased expression of toll-like-receptor 3 in intrahepatic biliary epithelial cells at sites of ductular reaction in diseased livers2008

    • Author(s)
      Nakamura M, Funami K, Komori A, Yokoyama T, Aiba A, et al
    • Journal Title

      Hepatology International 2

      Pages: 222-230

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article]2008

    • Author(s)
      中村稔, 下田愼治, 小森敦正, 石橋大海
    • Journal Title

      BIO Clinica(原発性胆汁性肝硬変における抗gp210抗体の臨床的意義)

      Pages: 1136-1143

    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Kondo H, Mori T, Komori A, Matsuyama M, Ito M et al.
    • Journal Title

      Hepatology 45

      Pages: 118-127

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] The predictive role of anti-gp210 and anti-centromere antibodies in the long-term outcome of PBC2007

    • Author(s)
      Nakamura M, Komori A, Ito M, Kondo H, Aiba Y, Migita K, Nagaoka S, et al.
    • Journal Title

      Hepatology Research (In press)

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis.2007

    • Author(s)
      Nakamura M, Kondo H, Mori T, Komori A, Matsuyama M et al.
    • Journal Title

      Hepatology 45

      Pages: 118-127

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] The predictive role of anti-gp210 and anti-centromere antibodies in the long-term outcome of PBC2007

    • Author(s)
      Nakamura M, Komori A, Ito M, Kondo H, Aiba Y, Migita K, et al.
    • Journal Title

      Hepatology Research (In press)

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mori T, Yatsuhashi H, Eguchi K, Ishibashi H
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] コランジオサイトのセルサイクルとその制御 -コランジオサイト研究の最近の展開-2006

    • Author(s)
      小森敦正, 瀧井康, 石橋大海, 中村 稔
    • Journal Title

      肝胆膵 53

      Pages: 1065-1071

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressive FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Yokoyama T, Takii Y, Mod T, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, et al., Ishibashi H.
    • Journal Title

      Liver International 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Human intrahepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kappaB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira T, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Ishibashi H
    • Journal Title

      Liver Int. 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Polymorhisms of interleukin-1beta in Japanese patients with hepatitis B virus infection.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Miyazoe S, Nakao K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      J Hepatol. (Epub ahead of print)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T et al.
    • Journal Title

      J Autoimmunity 26

      Pages: 133-145

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Human intra-hepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kB and MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira, Shimoda S, Mori T, Fujiwara S, Koyabu M, Taniguchi K
    • Journal Title

      Liver International 26(4)

      Pages: 467-476

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-alpha-stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, Ishibashi H, et al.
    • Journal Title

      Life Science

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Human intra-hepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kB and-MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M et al.
    • Journal Title

      Liver International (in press)

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H.
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Ishibashi H, et al.
    • Journal Title

      Journal of Autoimmunity 26(2)

      Pages: 138-145

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] コランジオサイトのセルサイクルとその制御-コランジオサイト研究の最近の展開-2006

    • Author(s)
      小森敦正, 瀧井康, 石橋大海, 中村 稔
    • Journal Title

      肝胆膵 53

      Pages: 1065-1071

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] コランジオサイトの免疫環境-コランジオサイト研究の最近の展開-2006

    • Author(s)
      中村 稔, 小森敦正, 石橋大海
    • Journal Title

      肝胆膵 53

      Pages: 1085-1091

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, et al. Ishibashi H
    • Journal Title

      J Autoimmunity 26(2)

      Pages: 138-45

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF- alpha- stimulated human hepatic stellate cells.2006

    • Author(s)
      Migita K, Maeda Y, Abiru S, Nakamura M, Komori A, et al., Ishibashi H.
    • Journal Title

      Life Sci. 78(21)

      Pages: 2510-2515

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Serum cytokine and soluble cytokine receptor levels in patients with non-alcoholic steatohepatitis.2006

    • Author(s)
      Abiru S, Migita K, Maeda Y, Daikoku M, Ito M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Liver Int. 26(1)

      Pages: 39-45

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Serum levels of interleukin-6 and its soluble receptors in patients with hepatitis C virus infection.2006

    • Author(s)
      Migita K, Abiru S, Maeda Y, Daikoku M, Ohata K, Nakamura M, Komori A, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      Human Immunol. 67(1-2)

      Pages: 27-32

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Human intra-hepatic biliary epithelial cells function in innate immunity by producing IL-6 and IL-8 via the TLR4-NF-kB and -MAPK signaling pathways.2006

    • Author(s)
      Yokoyama T, Komori A, Nakamura M, Takii Y, Kamihira et al.
    • Journal Title

      Liver International (in press)

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] コランジオサイトの免疫環境 -コランジオサイト研究の最近の展開-2006

    • Author(s)
      中村 稔, 小森敦正, 石橋大海
    • Journal Title

      肝胆膵 53

      Pages: 1085-1091

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis.2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y, Koyabu M, Matsuyama M, Mori T, Kamihira T, Daikoku M, Migita K, Yatsuhashi H, Nozaki N, Shimoda S, Ishibashi H
    • Journal Title

      J.Autoimmunity 26(2)

      Pages: 138-145

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Increased expression of nuclear envelope gp210 antigen in small bile ducts in primary biliary cirrhosis2006

    • Author(s)
      Nakamura M, Takii Y, Ito M, Komori A, Yokoyama T, Shimizu-Yoshida Y etal.
    • Journal Title

      J Autoimmunity 26

      Pages: 133-145

    • Data Source
      KAKENHI-PROJECT-17590696
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Shimizu-Yoshida Y, Nakao R, Kusumoto K, Nagaoka S, Yano K, Abiru S, Ueki T, Matsumoto T, Daikoku M, Taniguchi K, Fujioka H, Migita K, Yatsuhashi H, Nakashima M, Harada M, Ishibashi H
    • Journal Title

      Lab Invest. 85(7)

      Pages: 908-920

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Hen and egg, you mitochondrial PBC revisits mitochondria again.2005

    • Author(s)
      Komori A, Ishibashi H
    • Journal Title

      Hepatol Research 31(1)

      Pages: 1-2

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A et al., Ishibashi H
    • Journal Title

      Lab Invest. 85(7)

      Pages: 908-20

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Peroxynitrite-mediated matrix metalloproteinase-2 activation in human hepatic stellate cells.2005

    • Author(s)
      Migita K, Maeda Y, Abiru S, Komori A, Nakamura M, Ishibashi H, et al.
    • Journal Title

      FEBS Letter 579(14)

      Pages: 3119-3125

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Hen and egg, you mitochondria! PBC revisits mitochondria again.2005

    • Author(s)
      Komori A, Ishibashi H
    • Journal Title

      Hepatol Res. 31(1)

      Pages: 1-2

    • NAID

      10015455809

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Antibody titer to gp210-C terminal peptide as a clinical parameter for monitoring primary biliary cirrhosis.2005

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T, Ueki T, Daikoku M, Yano K, Matsumoto T, Migita K, Yatsuhashi H, Ito M, Masaki N, Adachi H, Watanabe Y, Nakamura Y, Saoshiro T, Sodeyama T, Koga M, Shimoda S, Ishibashi H
    • Journal Title

      J.Hepatol. 42(3)

      Pages: 386-392

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Enhanced expression of type I interferon and toll-like receptor-3 in primary biliary cirrhosis.2005

    • Author(s)
      Takii Y, Nakamura M, Ito M, Yokoyama T, Komori A, Ishibashi H, et al.
    • Journal Title

      Laboratory Investigation 85(7)

      Pages: 908-205

    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Hepatic expression of toll-like receptor 4 in primary biliary cirrhosis.2005

    • Author(s)
      Wang A-P, Migita K, Ito M, Takii Y, Daikoku M, Yokoyama T, Komori A, Nakamura M et al.
    • Journal Title

      J.Autoimmunity 25

      Pages: 85-91

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Anti-gp210 antibody titers as a clinical parameter that predicts the long-term outcome of primary biliary cirrhosis under ursodeoxycholic acid treatment.2004

    • Author(s)
      Nakamura M, Shimizu-Yoshida Y, Takii Y, Komori A, Yokoyama T et al.
    • Journal Title

      AASLD Abstract #679 (October 31, 2004. Boston)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Lipopolysaccharide signaling induces serum amyloid A (SAA) synthesis in human hepatocytes in vitro.2004

    • Author(s)
      Migita K, Abiru S, Nakamura M, Komori A, Yoshida Y, Yokoyama T, Daikoku M, Ueki T, Takii Y, Yano K, Yatsuhashi H, Eguchi K, Ishibashi H.
    • Journal Title

      FEBS Let. 569(1-3)

      Pages: 235-239

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Innate immune responses in human intrahepatic biliary epithelial cells via Toll-like receptors.2004

    • Author(s)
      Komori A, Yokoyama T, Takii Y, Nakamura M, Shimoda S et al.
    • Journal Title

      AASLD Abstract #597 (October 31, 2004. Boston)

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15390238
  • [Journal Article] Biliary epithelial cells and primary biliary cirrhosis : the role of liver- infiltrating mononuclear cells.

    • Author(s)
      Shimoda S, Harada K, Niiro H, Yoshizumi T, Soejima Y, Taketomi A, Maehara Y, Tsuneyama K, Nakamura M, Komori A, Migita K, Nakanuma Y, Ishibashi H, Selmi C, Gershwin ME.
    • Journal Title

      Hepatology 2008 47

      Pages: 958-65

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Journal Article] Single- nucleotide polymorphism analysis of the multidrug resistance protein 3 gene for the detection of clinical progression in Japanese patients with primary biliary cirrhosis.

    • Author(s)
      Ohishi Y, Nakamura M, Iio N, Higa S, Inayoshi M, Aiba Y, Komori A, Omagari K, Ishibashi H, Tsukamoto K
    • Journal Title

      Hepatology 2008 48

      Pages: 853-62

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 日本人原発性胆汁性肝硬変患者におけるTLIAの役割2013

    • Author(s)
      相葉佳洋, 原田憲一, 小森敦正, 伊東正博, 阿比留正剛, 長岡進矢, 石橋大海, 中沼安二, 八橋弘, 中村稔
    • Organizer
      第49回日本肝臓学会総会
    • Place of Presentation
      東京
    • Year and Date
      2013-06-06
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] WHO MAY HAVE TREATMENT BENEFITS WITH FIBRATES IN PRIMARY BILIARY CIRRHOSIS : A SINGLE CENTER RETROSPECTIVE OBSERVATIONAL COHORT ANALYSIS2013

    • Author(s)
      A. Komori, M. Nakamura, Y. Aiba, Y. Kugiyama-Yasunaga, S. Bekki, R. Sasaki, S. Hashimoto, M. Ootani, S.-K. Bae, A. Saeki, S. Nagaoka, S. Abiru, K. Yamasaki, H. Ishibashi, H. Yatsuhashi
    • Organizer
      48th annual meeting of the European Association for the Study of the Liver
    • Place of Presentation
      Amsterdam, The Netherlands
    • Year and Date
      2013-04-26
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Systemic and local expression of TNF-like ligand 1A and its decoy receptor 3 are increased in primary biliary cirrhosis.2013

    • Author(s)
      Yoshihiro Aiba, Kenichi Harada, Atsumasa Komori, Masahiro Ito, Shinji Shimoda, Shinya Nagaoka, Seigo Abiru, Kiyoshi Migita, Hiromi Ishibashi, Yasuni Nakanuma, Nao Nishida, Minae Kawashima, Katsushi Tokunaga, Hiroshi Yatsuhashi, Minoru Nakamura.
    • Organizer
      AASLD THE LIVER MEETING 2013
    • Place of Presentation
      Washington, DC, USA
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の肝局所におけるTL1A産生機構の解明2013

    • Author(s)
      相葉佳洋、原田憲一、小森敦正、阿比留正剛、長岡進矢、右田清志、伊東正博、中沼安二、八橋 弘、中村 稔
    • Organizer
      第50回日本消化器免疫学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] ヒト胆管上皮細胞におけるTL1A産生機構の解析2013

    • Author(s)
      相葉佳洋、小森敦正、伊東正博、右田清志、八橋 弘、中村 稔
    • Organizer
      第41回日本臨床免疫学会
    • Place of Presentation
      下関
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変におけるTL1Aの役割2013

    • Author(s)
      相葉佳洋、原田憲一、小森敦正、阿比留正剛、長岡進矢、右田清志、石橋大海、中沼安二、八橋 弘、中村 稔
    • Organizer
      第49回日本肝蔵学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] The mechanism of TL1A production in human biliary epithelial cells.2013

    • Author(s)
      Yoshihiro Aiba, Atsumasa Komori, Masahiro Ito, Kiyoshi Migita, Hiroshi Yatsuhashi, Minoru Nakamura.
    • Organizer
      第42回日本免疫学会総会
    • Place of Presentation
      幕張、千葉
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変のゲノムワイド関連解析2012

    • Author(s)
      中村稔, 西田奈央, 川嶋実苗, 田中篤, 中牟田誠, 太田肇, 竿代丈夫, 高野弘嗣, 吉澤要, 小森敦正, 梅村武司, 銭谷幹男, 恩地森一, 橋本悦子, 大平弘正, 山本和秀, 金子周一, 山際訓, 中尾一彦, 市田隆文, 滝川一, 前原喜彦, 上本伸一, 國土典宏, 坪内博仁, 溝上雅史, 徳永勝士, 中沼安二, 石橋大海
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変の病態形成に関与するHLA-A,-B,-DP,-DR遺伝子多型とCTLA-4, SLC4A2, IL12A, IRF5遺伝子多型の検討2012

    • Author(s)
      相葉佳洋, 安波道郎, 小森敦正, 右田清志, 八橋弘, 中牟田誠, 福嶋伸良, 太田肇, 石田仁也, 平田啓一, 渡部幸夫, 小松達司, 矢倉道泰, 高野弘嗣, 室豊吉, 島田昌明, 米田俊貴, 山下晴弘, 竹崎英一, 古賀満明, 小林正和, 杉和洋, 正木尚彦, 古澤要, 蒔田富士雄, 高木均, 西村英夫, 石橋大海, 中村稔
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変の病態形成に関与するHLA-A,-B,-DP,-DR 遺伝子多型とCTLA-4, SLC4A2, IL12A, IRF5 遺伝子多型の検討2012

    • Author(s)
      相葉 佳洋, 安波道郎, 小森敦正, 右田清志, 八橋 弘, et al
    • Organizer
      第48回 日本肝臓学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の治療におけるフィブレート製剤の効果と限界2012

    • Author(s)
      小森敦正, 中村稔, 伊東正博, 釘山有希, 戸次鎮宗, 福島真典, 橋元悟, 大谷正史, 裵成寛, 佐伯哲, 長岡進矢, 阿比留正剛, 八橋弘, 石橋大海
    • Organizer
      第48回日本肝臓学会総会
    • Place of Presentation
      金沢
    • Year and Date
      2012-06-07
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の自己抗体、病理学的スコア、治療反応性と予後の相関解析.2011

    • Author(s)
      中村 稔、伊東正博、山本和秀、大平弘正、銭谷幹男、田中 篤、橋本悦子、本多政夫、金子周一、上野義之、菊池健太郎、下田慎治、小森敦正、原田憲一、向坂彰太郎、滝川 一、恩地森一
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の自己抗体,病理学的スコア,治療反応性と予後の相関解析2011

    • Author(s)
      中村稔,伊東正博,山本和秀,太平弘正,銭谷幹男,田中篤,橋本悦子,本多政夫,金子周一,上野義之,菊池健太郎,下田慎治,小森敦正,原田憲一,向坂彰太郎,滝川一,恩地森一,西原利治,大西三朗,坪内博仁,中沼安二,石橋大海
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変におけるIL12A,IL12RB2,IRF5,染色体17q12-21領域の遺伝子多型の解析2011

    • Author(s)
      相葉佳洋、小森敦正、右田清志、八橋 弘、石橋大海、中村 稔
    • Organizer
      第48回日本消化器免疫学会総会
    • Place of Presentation
      金沢
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 国立病院機構肝疾患共同研究グループにおける原発性胆汁性肝硬変合併肝細胞癌2011

    • Author(s)
      小森敦正,中村稔,阿比留正剛,八橋弘,藤岡ひかる,石橋大海
    • Organizer
      第47回日本肝癌研究会
    • Place of Presentation
      静岡
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Positive Anti-GP210 Antibodies is a Risk Factor for Poor Biochemical Response to Ursodeoxycholic Acid Treatment in Japanese Patients with Primary Biliary Cirrhosis. 46th Annual Meeting of the European Association for the Study of the Liver2011

    • Author(s)
      M. Nakamura, M. Ito, K. Yamamoto, M. Zeniya, H. Ohira, E. Hashimoto, M. Honda, S. Kaneko, Y. Ueno, K. Kikuchi, S. Onji, S. Shimoda, H. Takikawa, A. Tanaka, A. Komori, H. Yatsuhashi, H. Kondo, K. Harada, S. Onishi, H. Tsubouchi, Y. Nakanuma, H. Ishibashi
    • Organizer
      The International Liver Congress 2011
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変における免疫関連分子の遺伝子多型の解析2011

    • Author(s)
      相葉佳洋,稲嶺達夫,城下智,小森敦正,右田清志,八橋弘,中牟田誠,福嶋伸良,竿代丈夫,林茂樹,渡部幸夫,矢倉道泰,高野弘嗣,室豊吉,太田肇,島田昌明,米田俊貴,山下晴弘,竹崎英一,古賀満明,小松達司,小林正和,杉和洋,高橋正彦,正木尚彦,吉澤要,塚元和弘,石橋大海,中村稔
    • Organizer
      第47回日本肝臓学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変の病態に準拠した治療方針;当科における後ろ向き解析2011

    • Author(s)
      小森敦正,中村稔,釘山有希,戸次鎮宗,福島真典,橋元悟,大谷正史,裵成寛,佐伯哲,長岡進矢,阿比留正剛,八橋弘,伊東正博,石橋大海
    • Organizer
      第98回日本消化器病学会九州支部例会,第92回日本消化器内視鏡学会九州支部例会
    • Place of Presentation
      長崎
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変におけるCTLA4,IL12A,IL12RB2,IRF5,染色体17q12-21領域の遺伝子多型の解析2011

    • Author(s)
      相葉佳洋、城下 智、吉澤 要、梅村武司、小森敦正、右田清志、八橋 弘、石橋大海、中村 稔
    • Organizer
      第39回日本臨床免疫学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 日本人原発性胆汁性肝硬変のOCT-1遺伝子の多型解析2011

    • Author(s)
      大石裕樹、石川奈緒子、石橋 誠、福嶋伸良、中牟田誠、相葉佳洋、小森敦正、石橋大海、中村 稔
    • Organizer
      第20回西日本臨床胆汁酸研究会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] 原発性胆汁性肝硬変において抗gp210抗体および抗セントロメア抗体は薬物治療効果の予測因子となり得るか2011

    • Author(s)
      福嶋伸良、中村 稔、福泉 公仁隆、吉本剛志、國府島 庸之、後藤 和人、河邉 顕、水谷 孝弘、小森敦正、原田直彦、中牟田誠、石橋大海、佐田通夫
    • Organizer
      第15回日本肝臓学会大会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23591006
  • [Presentation] Positive anti-gp210 antibodies is a strong risk factor for bile duct loss and hepatitis which induce jaundice-type progression of primary biliaruy cirrhosis in Japanese patients.2010

    • Author(s)
      Nakamura M, Ito M, Zeniya M, Ohira H, Hashimoto E, Kaneko S, Ueno Y, Kikuchi K, Onji M,Shimoda S, Komori A, Takikawa H, Onishi S, Tsubouchi H, Ishibashi H, Nakanuma Y
    • Organizer
      EASL The International Liver Congress 2010 (A1109)
    • Place of Presentation
      Vienna
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] ヒト肝内胆管細胞におけるSignal tranaducer and activator of transcription 3/5の役割2010

    • Author(s)
      小森敦正、相葉佳洋、中村稔、藤原紳祐、藤岡ひかる、右田清志、八橋弘、石橋大海
    • Organizer
      第46回日本肝臓学会総会(肝臓 51巻 2010, suppl.(1), A264)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変との関連が報告されている遺伝子多型の日本人でのreplication study.2010

    • Author(s)
      相葉佳洋、小森敦正、長岡進矢、阿比留正剛、右田清志、八橋弘、石橋大海、齋藤晃、中牟田誠、矢倉道泰、高野弘嗣、林茂樹、小松達司、渡部幸夫、小林正和、杉和洋、太田肇、島田昌明、米田俊貴、古賀満明、山下晴弘、竹崎英一、佐藤丈顕、高橋正彦、酒井浩徳、山本哲夫、正木尚彦、中村稔
    • Organizer
      第46回日本肝臓学会総会(肝臓 51巻 2010, suppl.(1), A342)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Signal Transducer and activator of transcription and 5 : Distinct regulators in growth and differentiation of human cholangiocyte in vitro.2010

    • Author(s)
      Komori A, Aiba Y, Nakamura M, Fujiwara S, Migita K, Fujioka H, Yatsuhashi H, Ishibashi H
    • Organizer
      EASL The International Liver Congress 2010 (A952)
    • Place of Presentation
      Vienna
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変における抗gp210抗体測定の意義の検証2010

    • Author(s)
      中村稔、伊東正博、山本和秀、銭谷幹男、大平弘正、橋本悦子、金子周一、上野義之、菊池健太郎、恩地森一、下田慎治、小森敦正、滝川一、大西三朗、坪内博仁、中沼安二、石橋大海
    • Organizer
      第46回日本肝臓学会総会(肝臓 51巻 2010, suppl.(1), A62.)
    • Place of Presentation
      山形
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] HLA-DRB1遺伝子多型が抗核抗体による原発性胆汁性肝硬変の予後予測に及ぼす影響の検討2009

    • Author(s)
      中村稔、安波道郎、近藤久義、相葉佳洋、小森敦正、長岡進矢、阿比留正剛、八橋弘、右田清志、石橋大海
    • Organizer
      第46回日本消化器免疫学会総会
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] PBC患者における血清BAFFの測定2009

    • Author(s)
      右田清志、中村稔、阿比留正剛、小森敦正、矢野公士、八橋弘、石橋大海
    • Organizer
      第45回日本肝臓学会総会(肝臓 50巻 2009, suppl.(1), A392, P-293.)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Analysis of HLA-DRB1 polymorphism in Japanese patients with primary biliary cirrhosis (PBC) - HLA-DRB1 polymorphism determines the relative risk of anti-nuclear antibodies for the disease-progression in PBC.2009

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Aiba Y, Komori A, Migita K, Yatsuhashi H, Nakamuta M, Hayashi S, Saito A, Honda K, Shimada M, Watanabe Y, Yagura M, Kohno H, Sugi K, Ota H, Komatsu T, Mannami T, Koga M, Satoh T, Takesaki E, Yamamoto T, Oohara Y, Masaki N, Ishibasi H
    • Organizer
      Hepatology(Volume 50, Number 4 (Suppl), October 2009, 1004A, 1521.)
    • Place of Presentation
      Boston
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変の予後診断法の確立のための遺伝子解析2009

    • Author(s)
      中村稔、塚元和弘、安波道郎、近藤久義、相葉佳洋, 小森敦正、右田清志、八橋弘、竿代丈夫、林茂樹、中牟田誠、本田浩一、杉和洋、島田昌明、小林正和、渡部幸夫、森本日出雄、矢倉道泰、正木尚彦、高野弘嗣、竹崎英一、小松達司、山下晴弘、加藤道夫、古賀満明、長岡進矢、矢野公士、阿比留正剛、石橋大海
    • Organizer
      第45回日本肝臓学会総会(肝臓 50巻 2009, suppl.(1), A162, 0-78.)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 当科におけるPBC-AIH overlap症候の特徴と予後2009

    • Author(s)
      小森敦正, 中村稔、本吉康英、橋元悟、裴成寛、立山雅邦、長岡進矢、柳謙二、田浦直太、阿比留正剛、矢野公士、右田清志、八橋弘、石橋大海
    • Organizer
      第45回日本肝臓学会総会(肝臓 50巻 2009, suppl.(1), A391,P-291.)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Hepatic expression of peroxisome proliferators activated receptors A(PPARA) in primary biliary cirrhosis.2009

    • Author(s)
      Nakamura M, Ito M, Aiba Y, Komori A, Migita K, Yatsuhashi H, Ishibashi H
    • Organizer
      Nuclear Receptors and Liver Disease.(Abstract page 87.)
    • Place of Presentation
      Vienna
    • Year and Date
      2009-02-28
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Analysis of HLA-DRB1 polymorphism in Japanese patients with primary biliary cirrhosis-HLA-DRB1 polymorphism determines the relative risk of anti-nuclear antibodies for the disease-progression in PBC.2009

    • Author(s)
      Nakamura M, Yasunami M, Kondo H, Aiba Y, Komori A, et al.
    • Organizer
      AASLD
    • Place of Presentation
      Boston, USA
    • Year and Date
      2009-11-03
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 日本人原発性胆汁性肝硬変(PBC)患者のCTLA-4一塩基多型(SNP)の解析2009

    • Author(s)
      相葉佳洋、中村稔、小森敦正、右田清志、八橋弘、塚本和弘、石橋大海
    • Organizer
      第46回日本消化器免疫学会総会
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Identification of serological and genetic biomarkers for predicting the prognosis of primary biliary cirrhosis (PBC)2008

    • Author(s)
      Nakamura M, Ohishi Y, Iio N, Aiba Y, Komori A, et al
    • Organizer
      The 59th Annual Meeting of The American Association for the Study of Liver Diseases (A ASLD)
    • Place of Presentation
      San Francisco, USA
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] OSTEOPONTIN, A PUTATIVE MARKER FOR DUCTULAR REACTION, IS INDUCED BY JAK/STAT3 ACTIVATION IN HUMAN BILIARY EPITHELIAL CELLS.2008

    • Author(s)
      Komori A, Uemura T, Fujiwara S, Aiba Y, Nakamura M, et al
    • Organizer
      The 43rd Annual Meeting of the European Association For the Study of the Liver.
    • Place of Presentation
      Milan, Italy
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 原発性胆汁性肝硬変の予後予測診断法の確立2008

    • Author(s)
      中村稔, 大石裕樹, 相葉佳洋, 小森敦正, 右田清志, 八橋弘, 竿代丈夫, 中牟田誠, 本田浩一, 島田昌明, 小林正和, 渡部幸夫, 林茂樹, 古賀満明, 森本日出雄, 正木尚彦, 近藤久義, 大曲勝久, 安波道郎, 塚元和弘, 石橋大海
    • Organizer
      第44回日本肝臓学会総会(肝臓 49巻 2008, suppl.(1), A184, 0-115.)
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] 培養ヒト肝内胆管上皮細胞の急性相反応からみた遺伝子発現の可能性2008

    • Author(s)
      小森敦正, 植村隆, 藤原紳祐, 相葉佳洋, 中村稔, 矢野公士, 藤岡ひかる, 右田清志, 八橋弘, 石橋大海
    • Organizer
      第44回日本肝臓学会総会(一般演題,セッション60:胆管・胆汁うっ滞2)(肝臓 49 Suppl.(1):A235,2008.04.30)
    • Place of Presentation
      愛媛
    • Data Source
      KAKENHI-PROJECT-20590800
  • [Presentation] Identification of serological and genetic biomarkers for predicting the prognosis of primary biliary cirrhosis (PBC). -A homozygous "Hap2/Hap2" diplotype in multidrug resistance protein 3 (MDR3) gene confers a strong susceptibility to jaundice-type progression of PBC-2008

    • Author(s)
      Nakamura M, Ohishi Y, Iio N, Aiba Y, Komori A, et al
    • Organizer
      The 59th Annual Meeting of The American Association for the Study of Liver Diseases (AASLD).
    • Place of Presentation
      San Francisco
    • Data Source
      KAKENHI-PROJECT-20590800
  • 1.  NAKAMURA Minoru (40217906)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 111 results
  • 2.  ISHIBASHI Hiromi (80127969)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 84 results
  • 3.  MIGITA Kiyoshi (60264214)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 36 results
  • 4.  ITO Masahiro (30184691)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 8 results
  • 5.  神津 知子 (60161874)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  AIBA Yoshihiro (70450955)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 21 results
  • 7.  SHIMODA Shinji (30279319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 8.  YATSUHASHI Hiroshi (50360855)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 9.  藤木 博太 (60124426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  原 栄一 (30164990)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  岡部 幸子 (10270604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  末岡 榮三朗 (00270603)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  菅沼 雅美 (20196695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  藤岡 ひかる (00264226)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 15.  喜多 宏人 (80294974)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  原田 憲一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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