Tezuka Kenichi 手塚建一

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Tezuka Ken-ichi 手塚建一

TEZUKA Ken-ichi 手塚建一

手塚建一テヅカケンイチ

KENICHI Tezuka 手塚建一

手塚健一テヅカケンイチ

TEZUKA Kenichi 手塚建一

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Researcher Number	50236973
Other IDs
External Links
Affiliation (Current)	2026: 岐阜大学, 大学院医学系研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 岐阜大学, 大学院医学系研究科, 准教授 2011 – 2015: 岐阜大学, 医学(系)研究科(研究院), 准教授 2014: 岐阜大学, 医学部, 准教授 2007 – 2008: Gifu University, 大学院・医学系研究科, 准教授 2005: Gifu University, Graduate School of Medicine, Associate Professor, 大学院・医学系研究科, 助教授 … More 2002 – 2004: 岐阜大学, 大学院・医学研究科, 助教授 2001: 東京理科大学, 生命科学研究所, 専任講師 2000 – 2001: 東京理科大学, 生命科学研究所, 講師 1998 – 2001: 東京理科大学, 生命科学研究所・生命工学技術部門, 講師 1992 – 1993: 明海大学, 歯学部, 助手 Less
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Morphological basic dentistry / Basic Section 57040:Regenerative dentistry and dental engineering-related / Medium-sized Section 57:Oral science and related fields Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Urology / Orthopaedic surgery / Periodontal dentistry / Morphological basic dentistry / Orthopaedic surgery
Keywords	Principal Investigator 再生医療 / 歯髄細胞 / Zinc Finger Nuclease / iPS細胞 / 有限要素法 / 骨リモデリング / トレーサビリティ / ゲノム編集 / HLA / ヒト白血球抗原 … More / 大理石病 / シミュレーション / 反応拡散系 / 間葉系幹細胞 / 細胞接着分子 / EGFリピート / Notch / 骨芽細胞 / エクソソーム / 三次元培養 / トレーサビリティー / AI / CRISPR / 乳歯 / zinc finger nuclease / Symbol / ブロックチェーン / iPS細胞ストック / Mandible / Reaction-diffusion system / Finite element analysis / Computer simulation / Bone remodeling / シミュレーションバイオロジー / 骨髄炎 / 軟骨形成 / 骨細胞 / ゲノムエディティング / 次世代シーケンサー / 他家移植 / 無血清培地 / 人工多能性幹細胞 / Human Leucocyte Antigen / HLAタイプ / センダイウイルスベクター / 顎変形症 / 開咬 / 力学ストレス / コンピュータシミュレーション / opマウス / op / 計算機シミュレーション / メカニカルストレス / 軟骨細胞 / 造血幹細胞 / PCクラスタ / インテグリン / cDNAクローニング / 細胞接着因子 / matrix metalloproteinase9 / GM2 activator protein / vacuolar type H^+-ATPase / carbonic anhydrase II / cDNA / 破骨細胞 … More Except Principal Investigator bcl-2 / ATDC5 / Notch / NOD / 歯髄細胞 / FGF2 / エクソソーム / NFkappaB / angiogenesis / bone metastases / prostate cancer / 血管内皮細胞 / レトロウイルスベクター / ヒト腫瘍血管新 / SCIDマウス / 遺伝子治療 / ヒト腫瘍血管新生 / VEGF / NFκB / 血管新生 / 骨転移 / 前立腺癌 / Adenovirus vector / MC3T3-EI / Human mesenchymal stem cells / HuBone-NOD-SCID mice / 運動療法 / 力学負荷 / POEM / 軟骨細胞 / 内軟骨性骨化 / 骨芽細胞 / Signal Sequence Trap / アデノウイルスベクター / MC3T3-E1 / ヒト間葉系幹細胞 / HuBone-NOD-SCIDマウス / CD4+ T cells / human immune response / periodontitis / Actinohacilllis actinnmycetemcomitans / NOD-SCID mouse / IgG / Limiting Dilution Assay / Actinobacillus actionomycetemcomitans / SCODマウス / CD4^+T細胞 / ヒトリンパ球 / Actinobacillus actinomycetemcomitans / プラーク(細菌塊) / NOD-SCIDマウス / OSTEOCLAST FUNCTION / OSTEOCLAST FORMATION / OSTEOCYTES / CYTOKINES / ホルモン / 骨形成 / Bone cell / cathepsin-L様物質 / osteopontin / 破骨細胞 / 骨吸収 / TGF-β / 破骨細胞機能 / 破骨細胞形成 / 骨細胞 / サイトカイン / 神経栄養因子 / 再生医療 / 細胞移植 / 脊髄損傷 Less

Development of traceability system for medical usage of human cells -large scale production of dental pulp cell exosomes-Principal Investigator
- Principal Investigator
  
  手塚建一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Gifu University
FGF２刺激歯髄細胞由来エクソソームの歯周組織再生に向けた評価
- Principal Investigator
  
  川口知子 (武田知子)
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Gifu University
HLA genome editing of dental pulp cells for iPS cell stock.Principal Investigator
- Principal Investigator
  
  Tezuka Ken-ichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Gifu University
Genetic Modulation of iPS Cells in HLA Loci Using Zinc Finger NucleasesPrincipal Investigator
- Principal Investigator
  
  Tezuka Ken-ichi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Gifu University
Characterization and medical application of human dental pulp cells for spinal cord injury
- Principal Investigator
  
  FURUKAWA Shoei
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Gifu Pharmaceutical University
Establishment of iPS cell lines from dental pulp cells using Sendai virus vectorsPrincipal Investigator
- Principal Investigator
  
  TEZUKA Ken-ichi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Gifu University
ヒト骨疾患シミュレーションのための骨成長モデルの構築Principal Investigator
- Principal Investigator
  
  手塚建一
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Gifu University
Remodeling simulation of human bone structuresPrincipal Investigator
- Principal Investigator
  
  TEZUKA Ken-ichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Gifu University
複雑系シミュレーションを基礎とした新しい骨再生ストラテジーの研究Principal Investigator
- Principal Investigator
  
  手塚建一
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Gifu University
Development of bone regeneration therapy for osteoporosis using humanized mice
- Principal Investigator
  
  TOYAMA Yoshiaki
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Keio University
Establishment of a novel mouse model for studying prostate cancer metastasis to human bone and new therapeutic strategies.
- Principal Investigator
  
  MURAI Masaru
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Urology
- Research Institution
  KEIO UNIVERSITY
Analysis of human immune response in periodontitis using a noble mouse model
- Principal Investigator
  
  NOBUMICHI Hozumi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Tokyo University of Science
Notchによる骨形成促進機構の解明と骨粗鬆症治療への応用Principal Investigator
- Principal Investigator
  
  手塚建一
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo University of Science
骨芽細胞の分化を制御する新規EGFリピート分子のクローニングと機能解析Principal Investigator
- Principal Investigator
  
  手塚建一
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokyo University of Science
破骨細胞に特異的に発現している遺伝子の単離と解析Principal Investigator
- Principal Investigator
  
  手塚健一
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University
Regulation of bone metabolism - especially by bone cell interaction
- Principal Investigator
  
  KUMEGAWA Masayoshi
- Project Period (FY)
  1991 – 1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Meikai University

[Book] ブロックチェーン3.02020
- Author(s)
  手塚建一
- Total Pages
  440
- Publisher
  NTS
- ISBN
  9784860436827
- Data Source
  KAKENHI-PROJECT-19K22707
[Book] 再生医療叢書　第８巻2012
- Author(s)
  手塚建一、柴田敏之、國貞隆弘
- Total Pages
  185
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23592697
[Book] 再生医療叢書第8巻2012
- Author(s)
  手塚建一、柴田敏之、國貞隆弘
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-23592697
[Book] 骨粗耘症-臨床と研究の最新動向2008
- Author(s)
  手塚建一, 上岡寛
- Total Pages
  133
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-19659480
[Book] 培養細胞実験ハンドブック2004
- Author(s)
  手塚建一
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Effects of FGF2 Priming and Nrf2 Activation on the Antioxidant Activity of Several Human Dental Pulp Cell Clones Derived From Distinct Donors, and Therapeutic Effects of Transplantation on Rodents With Spinal Cord Injury2024
- Author(s)
  Fukumitsu Hidefumi、Soumiya Hitomi、Nakamura Kaito、Nagashima Kosuke、Yamada Makoto、Kobayashi Hiroyuki、Miwa Takahiro、Tsunoda Atsuki、Takeda-Kawaguchi Tomoko、Tezuka Ken-ichi、Furukawa Shoei
- Journal Title
  
  Cell Transplantation
  
  Volume: 33 Pages: 1-18
- DOI
  10.1177/09636897241264979
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06132, KAKENHI-PROJECT-23K09393
[Journal Article] Exosomes from dental pulp cells attenuate bone loss in mouse experimental periodontitis2021
- Author(s)
  Shimizu Yuta、Takeda‐Kawaguchi Tomoko、Kuroda Izumi、Hotta Yasuaki、Kawasaki Hideya、Hariyama Takahiko、Shibata Toshiyuki、Akao Yukihiro、Kunisada Takahiro、Tatsumi Junichi、Tezuka Ken‐ichi
- Journal Title
  
  Journal of Periodontal Research
  
  Volume: 57 Issue: 1 Pages: 162-172
- DOI
  10.1111/jre.12949
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08784, KAKENHI-PROJECT-20K07390, KAKENHI-PROJECT-20K10158, KAKENHI-PROJECT-19K22707, KAKENHI-PROJECT-19K10263
[Journal Article] 歯髄細胞からのiPS細胞樹立2020
- Author(s)
  川口知子，手塚建一
- Journal Title
  
  整形・災害外科
  
  Volume: 63 Pages: 1573-1577
- Data Source
  KAKENHI-PROJECT-19K22707
[Journal Article] FGF2-Responsive Genes in human Dental Pulp Cells Assessed using a Rat Spinal Cord Injury Model2018
- Author(s)
  Ken Sugiyama, Kosuke Nagashima, Takahiro Miwa, Yuta Shimizu, Tomoko Kawaguchi, Kazuki Iida, Naritaka Tamaoki, Daijiro Hatakeyama, Hitomi Aoki, Chikara Abe, Hironobu Morita, Takahiro Kunisada, Toshiyuki Shibata, Hidefumi Fukumitsu, and Ken-ichi Tezuka
- Journal Title
  
  Journal of Bone and Mineral Metabolism.
  
  Volume: 印刷中 Issue: 3 Pages: 467-474
- DOI
  10.1007/s00774-018-0954-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06731, KAKENHI-PROJECT-26293426, KAKENHI-PROJECT-19K22707, KAKENHI-PROJECT-17K11830
[Journal Article] HLAハプロタイプホモ歯髄細胞の収集と再生医療への応用2016
- Author(s)
  手塚　建一
- Journal Title
  
  腎と骨代謝
  
  Volume: 29 Pages: 59-67
- Data Source
  KAKENHI-PROJECT-26670799
[Journal Article] Hypoxia-enhanced Derivation of iPSCs from Human Dental Pulp Cells2013
- Author(s)
  K.Iida,T.Kawaguchi,M.Hada,M.Yuriguchi,H.Aoki,NTamaoki,D.Hatakeyama,T.Kunisada,T.Shibata,K.Tezuka
- Journal Title
  
  Journal of Dental Research
  
  Volume: 92 Issue: 10 Pages: 905-910
- DOI
  10.1177/0022034513502204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390383, KAKENHI-PROJECT-23592697, KAKENHI-PROJECT-23592917, KAKENHI-PROJECT-23792328
[Journal Article] Dual origin of melanocytes defined by Sox 1 expression and their region-specific distribution in mammalian skin.2013
- Author(s)
  Naoko Yoshimura, Tsutomu Motohashi, Hitomi Aoki, Ken-ichi Tezuka, Natsuki Watanabe, Takanori Wakaoka, Takumi Era, Takahiro Kunisada
- Journal Title
  
  Development, Growth and Differentiation
  
  Volume: 55 Issue: 2 Pages: 270-281
- DOI
  10.1111/dgd.12034
- NAID
  40019734976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590233, KAKENHI-PROJECT-23592697, KAKENHI-PROJECT-25505002, KAKENHI-PROJECT-25670092
[Journal Article] A more efficient method to generate integration-free human iPS cells.2011
- Author(s)
  K Okita, Y Matsumura, Y Sato, A Okada, A Morizane, S Okamoto, H Hong, M Nakagawa, K Tanabe, K Tezuka, T Shibata, T Kunisada, M Takahashi, J Takahashi, H Saji, S Yamanaka
- Journal Title
  
  Nature Methods
  
  Volume: 8 Pages: 409-412
- NAID
  120002949763
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592697
[Journal Article] メカニカルストレスと骨〜骨細胞の生物学から骨リモデリングシミュレーションヘ〜2007
- Author(s)
  手塚建一、上岡寛
- Journal Title
  
  医学のあゆみ 221
  
  Pages: 76-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659480
[Journal Article] Computer simulation of human mandible bone structure by iBone, a novel reaction-diffusion bone remodeling model.2006
- Author(s)
  Ken-ichi Tezuka
- Journal Title
  
  Key Engineering Materials vols.306-308
  
  Pages: 1277-1282
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Computer simulation of human mandible bone structure by iBone, a novel reaction-diffusion bone remodeling model.2006
- Author(s)
  Ken-ichi Tezuka, Tomoko Takeda, Yoshitaka Wada, Akiyuki Takahashi, Masanori Kikuchi
- Journal Title
  
  Key Engineering Materials 306-308
  
  Pages: 1277-1282
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Computer simulation of human mandible bone structure by iBone, a novel reaction-diffusion bone remodeling model.2006
- Author(s)
  Ken-ichi Tezuka
- Journal Title
  
  Key Engineering Materials 306-308
  
  Pages: 1277-1282
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Computer-simulated bone architecture in a simple bone-remodeling model based on a reaction-diffusion system.2005
- Author(s)
  Ken-ichi Tezuka
- Journal Title
  
  J. Bone Miner. Metabol. 23
  
  Pages: 1-7
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Expression of Cre recombinase in the mouse developing chondrocytes driven by the mouse a2(XI) collagen promoter.2005
- Author(s)
  Ryoji Fujimaki, Katsuhiko Hayashi, Naoko Watanabe, Taketo Yamada, Yoshiaki Toyama, Ken-ichi Tezuka, Nobumichi Hozumi
- Journal Title
  
  J.Bone Miner.Metabol. 23
  
  Pages: 270-273
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Computer-simulated bone architecture in a simple bone-remodeling model based on a reaction-diffusion system.2005
- Author(s)
  Ken-ichi Tezuka
- Journal Title
  
  J.Bone Miner.Metabol. 23
  
  Pages: 1-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Computer-simulated bone architecture in a simple bone-remodeling model based on a reaction-diffusion system.2005
- Author(s)
  Ken-ichi Tezuka, Yoshitaka Wada, Akiyuki Takahashi, Masanori Kikuchi
- Journal Title
  
  J.Bone Miner.Metabol. 23
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-16591823
[Journal Article] Three-dimensional reconstruction of chick calvarial osteocytes and their cell process using confocal microscopy.2005
- Author(s)
  Yasuko Sugawara, Hiroshi Kamioka, Tadashi Honjo, Ken-ichi Tezuka, Teruko Takano-Yamamoto
- Journal Title
  
  Bone 36
  
  Pages: 877-883
- Data Source
  KAKENHI-PROJECT-16591823
[Patent] 人工多能性幹細胞の作製方法2013
- Inventor(s)
  手塚建一他７名
- Industrial Property Rights Holder
  手塚建一他７名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-176647
- Filing Date
  2013-08-28
- Data Source
  KAKENHI-PROJECT-23592697
[Patent] Efficient method for establishing induced pluripotent stem cells.2013
- Inventor(s)
  Tezuka K et al.
- Industrial Property Rights Holder
  岐阜大学、京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-01-22
- Overseas
- Data Source
  KAKENHI-PROJECT-23592697
[Patent] 人工多能性幹細胞の作製方法2013
- Inventor(s)
  手塚建一他7名
- Industrial Property Rights Holder
  岐阜大学、産総研
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-176647
- Filing Date
  2013-08-28
- Overseas
- Data Source
  KAKENHI-PROJECT-23592697
[Patent] Efficient method for establishing induced pluripotent stem cells2013
- Inventor(s)
  Tezuka K et al
- Industrial Property Rights Holder
  岐阜大学、京都大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-01-22
- Overseas
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 米糊粉細胞由来エクソソーム様ナノ粒子は歯周炎の進行を抑制する2024
- Author(s)
  川口知子、杉戸信彦、清水雄太、飯田一規、黒田依澄、飯尾明生、手塚建一、山田陽一、赤尾幸博
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K09393
[Presentation] ヒト歯髄細胞のHLA-A領域に対する選択的ゲノム編集2024
- Author(s)
  黒田依澄、川口知子、青木仁美、本橋力、手塚建一
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K09393
[Presentation] ブロックチェーンを用いたヒト歯髄細胞の流通・製造トレーサビリティーソリューション:ShizuiNet2024
- Author(s)
  手塚建一、川口知子、黒田依澄
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K09393
[Presentation] マウス歯周炎モデルを用いた歯髄細胞エクソソーム精製方法の検討2024
- Author(s)
  清水雄太、川口知子、黒田依澄、辰巳順一、手塚建一
- Organizer
  第23回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-23K09393
[Presentation] ブロックチェーンを用いたヒト歯髄細胞・iPS 細胞の流通・製造追跡システム「ShizuiNet」2023
- Author(s)
  手塚建一, 黒田依澄, 川口知子, 清水雄太
- Organizer
  第41回日本骨代謝学会
- Data Source
  KAKENHI-PROJECT-23K09393
[Presentation] ヒト歯髄細胞のHLA-A領域に対する選択的ゲノム編集2022
- Author(s)
  黒田依澄, 有本周平, 川口知子, 青木仁美 , 本橋力, 國貞隆弘, 手塚建一
- Organizer
  第21回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] ヒト歯髄細胞エクソソームは歯周炎の進行を抑制する2022
- Author(s)
  清水雄太, 川口知子, 黒田依澄, 飯田一規 , 畠山大二郎, 辰巳順一, 手塚建一
- Organizer
  第21回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] ブロックチェーン技術を用いた細胞トレーサビリティソリューション2021
- Author(s)
  手塚建一
- Organizer
  第20回日本再生医療学会テクノオークション
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] NEMブロックチェーンを用いた細胞流通・系譜記録システム「ShizuiNet」2021
- Author(s)
  手塚建一, 望月こもも, 黒田依澄, 川口知子，上岡寛
- Organizer
  第20回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] ヒト歯髄細胞由来iPS細胞からのエクソソームの精製2021
- Author(s)
  川口知子, 清水雄太, 黒田依澄, 飯田一規 , 畠山大二郎, 國貞隆弘, 柴田敏之, 手塚建一
- Organizer
  第20回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] 畳み込みニューラルネットワークを用いた培養歯髄細胞密度評価法：ShizuiAI2020
- Author(s)
  手塚建一,高橋滉平,川口知子,清水雄太,黒田依澄
- Organizer
  第19回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] 歯髄細胞由来エクソソームの特性評価およびLPS誘導性歯周炎モデルへの応用2020
- Author(s)
  川口知子, 清水雄太, 黒田依澄, 柴田敏之, 國貞隆弘, 手塚建一
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] 畳み込みニューラルネットワークを用いた培養歯髄細胞密度評価法:ShizuiAI2020
- Author(s)
  手塚建一,高橋滉平,川口知子,清水雄太,黒田依澄
- Organizer
  第19回日本再生医療学会
- Data Source
  KAKENHI-PROJECT-19K22707
[Presentation] 脊髄損傷治療を目的としたヒト歯髄細胞のFGF2に対するドナー個人差の検討2016
- Author(s)
  杉山　健，飯田一規, 川口知子,　畠山大二郎, 柴田敏之，手塚建一
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] Genome Editing of HLA Locus Using Zinc Finger Nucleases.2015
- Author(s)
  Ken-ichi Tezuka, Shunji Chikusa, Shota Ishii, Ken Sugiyama, Tomoko Kawaguchi-Takeda
- Organizer
  27th European Conference on Biomaterials
- Place of Presentation
  クラクフ（ポーランド）
- Year and Date
  2015-08-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] HLAハプロタイプホモ歯髄細胞による再生医療2015
- Author(s)
  手塚　建一
- Organizer
  第３０回老化促進マウス(SAM) 研究協議会
- Place of Presentation
  岐阜
- Year and Date
  2015-07-05
- Invited
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] 脊髄損傷治療を目的としたヒト歯髄細胞のFGF2に対する応答性の検討2015
- Author(s)
  杉山　健，川口知子,　手塚建一
- Organizer
  第16回運動器科学研究会
- Place of Presentation
  鹿児島
- Year and Date
  2015-09-11
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] 脊髄損傷治療を目的としたヒト歯髄細胞のFGF2に対する応答性の検討2015
- Author(s)
  杉山　健, 川口　知子, 手塚　建一
- Organizer
  第３３回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] HLAハプロタイプ資源としての歯髄細胞2015
- Author(s)
  手塚　建一
- Organizer
  第６０回日本口腔外科学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-17
- Invited
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] 骨特異的遺伝子の分子クローニング2015
- Author(s)
  手塚　建一
- Organizer
  第３３回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-07-23
- Invited
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] ヒト歯髄細胞の移植による脊髄損傷モデルラットの運動機能回復に関する研究2014
- Author(s)
  長島光助、福光秀文、宗宮仁美、國貞隆弘、柴田敏之、手塚建一、古川昭栄
- Organizer
  日本薬学会東海支部
- Place of Presentation
  鈴鹿
- Year and Date
  2014-07-05
- Data Source
  KAKENHI-PROJECT-25670654
[Presentation] Zinc Finger Nucleaseを用いたヒト歯髄細胞におけるHLA-A2の遺伝子改変2014
- Author(s)
  千種　俊士、武田　知子、手塚　建一
- Organizer
  第３２回日本骨代謝学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-07-25
- Data Source
  KAKENHI-PROJECT-26670799
[Presentation] 岐阜歯髄細胞コレクション〜未来の再生医療を支えるためにできること〜2014
- Author(s)
  手塚建一
- Organizer
  岐阜歯科学会40周年記念大会
- Place of Presentation
  岐阜
- Year and Date
  2014-01-12
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 再生医療資源としての歯髄細胞利用2013
- Author(s)
  手塚建一
- Organizer
  歯科基礎医学会サテライトシンポジウム
- Place of Presentation
  岡山
- Year and Date
  2013-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 日本人HLAハプロタイプホモ歯髄細胞コレクション2013
- Author(s)
  手塚建一
- Organizer
  明海大学歯学部研修会
- Place of Presentation
  埼玉
- Year and Date
  2013-02-22
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 岐阜県が日本を救う?～親知らずからiPS細胞～2013
- Author(s)
  手塚建一
- Organizer
  岐阜大学フェア
- Place of Presentation
  高山
- Year and Date
  2013-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking2013
- Author(s)
  Ken-ichi Tezuka
- Organizer
  Kyudai Oral Bioscience 2013 -7th International Symposium
- Place of Presentation
  福岡
- Year and Date
  2013-03-08
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking2013
- Author(s)
  Ken-ichi Tezuka, Tomoko Kawaguchi, Naritaka Tamaoki, Kazuki Iida, Hitomi Aoki, Toshiyuki Shibata, Takahiro Kunisada
- Organizer
  2013 Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  Baltimore
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking2013
- Author(s)
  Ken-ichi Tezuka
- Organizer
  6th International Symposiumon the Biology of Tertrate- Resistant Acid Phosphatase
- Place of Presentation
  神戸
- Year and Date
  2013-05-27
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking - A low cost human cell resource for regenerative medicine-2013
- Author(s)
  Ken-ichi Tezuka
- Organizer
  5th Hiroshima Conference on Education and Science in Dentistry
- Place of Presentation
  広島
- Year and Date
  2013-10-13
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 日本人HLAハプロタイプホモ歯髄細胞コレクション2013
- Author(s)
  手塚建一
- Organizer
  名古屋大学IGER SEMINAR
- Place of Presentation
  名古屋
- Year and Date
  2013-01-17
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 親知らずからiPS細胞～歯の中にあるたからもの～2013
- Author(s)
  手塚建一
- Organizer
  岐阜市母子寡婦福祉大会講演会
- Place of Presentation
  岐阜
- Year and Date
  2013-09-23
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Source for iPS Cell Banking.2013
- Author(s)
  Ken-ichi Tezuka, Tomoko Kawaguchi, Naritaka Tamaoki, Kazuki Iida, Hitomi Aoki, Toshiyuki Shibata, Takahiro Kunisada
- Organizer
  2013 Annual Meeting of the American Society for Bone and Mineral Research
- Place of Presentation
  ボルチモア
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking2013
- Author(s)
  Ken-ichi Tezuka
- Organizer
  CiRA Symposium 2013
- Place of Presentation
  京都
- Year and Date
  2013-03-11
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Generation of integration-free human dental-pulp-derived iPS cells from HLA-homozygous donors using Sendai virus vectors.2012
- Author(s)
  Noemi Fusaki, Hiroshi Ban, Masataka Hada, Akihiro Iida, Mamoru Hasegawa, Kunisada and Ken-ichi Tezuka
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Generation of integration-free human dental-pulp-derived iPS cells from HLA-homozygous donors using Sendai virus vectors2012
- Author(s)
  Noemi Fusaki, Hiroshi Ban, Masataka Hada, Akihiro Iida, Mamoru Hasegawa, Kunisada and Ken-ichi Tezuka
- Organizer
  10th Annual Meeting of International Society for Stem Cell Research
- Place of Presentation
  Yokohama, Japan
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] iPS細胞バンクのための歯髄細胞バンク構築2011
- Author(s)
  手塚　建一
- Organizer
  第65回日本口腔科学会学術集会(招待講演)
- Place of Presentation
  タワーホール船堀
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 計算機シミュレーションiBoneを使ったテーラーメイド再生医療(特別講演)2008
- Author(s)
  手塚建一
- Organizer
  日本歯科理工学会中部支部夏期セミナー
- Place of Presentation
  岐阜十八楼
- Year and Date
  2008-08-21
- Data Source
  KAKENHI-PROJECT-19659480
[Presentation] コンピュータシミュレーションによるヒト下顎骨内部構造の再現2007
- Author(s)
  手塚健一、山口徹太郎
- Organizer
  第25回日本骨代謝学会ポスター発表
- Place of Presentation
  大阪国際会議場
- Data Source
  KAKENHI-PROJECT-19659480
[Presentation] FGF2 で処理したヒト歯髄細胞の移植による脊髄損傷モデルラットの運動機能回復効果
- Author(s)
  福光秀文、長島光助、宗宮仁美、後大輔、三輪高大、柴田敏之、國貞隆弘、手塚建一、古川昭栄
- Organizer
  日本薬学会　第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-25670654
[Presentation] 岐阜歯髄細胞コレクション～未来の再生医療を支えるためにできること～
- Author(s)
  手塚　建一
- Organizer
  岐阜歯科学会４０周年記念大会
- Place of Presentation
  岐阜
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 岐阜県が日本を救う？～親知らずからiPS細胞～
- Author(s)
  手塚　建一
- Organizer
  岐阜大学フェア
- Place of Presentation
  高山
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking.
- Author(s)
  Ken-ichi Tezuka
- Organizer
  Kyudai Oral Bioscience 2013 -7th International Symposium
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Source for iPS Cell Banking.
- Author(s)
  Ken-ichi Tezuka
- Organizer
  6th International Symposium on the Biology of Tertrate-Resistant Acid Phosphatase
- Place of Presentation
  神戸
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 日本人HLAハプロタイプホモ歯髄細胞コレクション
- Author(s)
  手塚　建一
- Organizer
  明海大学歯学部研修会
- Place of Presentation
  埼玉
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 日本人HLAハプロタイプホモ歯髄細胞コレクション
- Author(s)
  手塚　建一
- Organizer
  名古屋大学 IGER SEMINAR
- Place of Presentation
  名古屋
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 親知らずからiPS細胞～歯の中にあるたからもの～
- Author(s)
  手塚　建一
- Organizer
  岐阜市母子寡婦福祉大会　講演会
- Place of Presentation
  岐阜
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] 再生医療資源としての歯髄細胞利用
- Author(s)
  手塚　建一
- Organizer
  歯科基礎医学会　サテライトシンポジウム
- Place of Presentation
  岡山
- Invited
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking.
- Author(s)
  Ken-ichi Tezuka
- Organizer
  CiRA Symposium 2013
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23592697
[Presentation] Dental Pulp Cells as Souce for iPS Cell Banking -A low cost human cell resource for regenerative medicine-
- Author(s)
  Tezuka K.
- Organizer
  5th Hiroshima Conference on Education and Science in Dentistry
- Place of Presentation
  広島
- Invited
- Data Source
  KAKENHI-PROJECT-23592697

1. NOBUMICHI Hozumi (60051744)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. HAKEDA Yoshiyuki (90164772)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. YAMADA Taketo (60230463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 川口知子 (30509815)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. FURUKAWA Shoei (90159129)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. FUKUMITAU Hidefumi (00308280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. SOUMIYA Hitomi (20548713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. KUNISADA Takahiro (30205108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. SHIBATA Toshiyuki (50226172)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. KUMEGAWA Masayoshi (40049367)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAKAHARA Hiroshi (70049344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TOYAMA Yoshiaki (40129549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MURAI Masaru (90101956)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OYA Mototsugu (00213885)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. NAKASHIMA Jun (10167546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 菊池正紀 (90107540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 堀内圭輔 (30327564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岩本潤 (40245527)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 上岡寛 (80253219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 飯田一規 (30585237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. OHTA Hideo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. ITO Fumio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KATO Keizou

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. WAKAOKA Takanori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 杉山健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 畠山大二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 河崎秀陽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 本橋力

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tezuka Kenichi 手塚 建一

Tezuka Ken-ichi 手塚 建一

TEZUKA Ken-ichi 手塚 建一

手塚 建一 テヅカ ケンイチ

KENICHI Tezuka 手塚 建一

手塚 健一 テヅカ ケンイチ

TEZUKA Kenichi 手塚 建一

Research Projects

Research Products

Co-Researchers

Development of traceability system for medical usage of human cells -large scale production of dental pulp cell exosomes-Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

FGF２刺激歯髄細胞由来エクソソームの歯周組織再生に向けた評価

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

HLA genome editing of dental pulp cells for iPS cell stock.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genetic Modulation of iPS Cells in HLA Loci Using Zinc Finger NucleasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization and medical application of human dental pulp cells for spinal cord injury

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Establishment of iPS cell lines from dental pulp cells using Sendai virus vectorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト骨疾患シミュレーションのための骨成長モデルの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Remodeling simulation of human bone structuresPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

複雑系シミュレーションを基礎とした新しい骨再生ストラテジーの研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of bone regeneration therapy for osteoporosis using humanized mice

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Establishment of a novel mouse model for studying prostate cancer metastasis to human bone and new therapeutic strategies.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of human immune response in periodontitis using a noble mouse model

Principal Investigator

Project Period (FY)

Research Category

Tezuka Kenichi 手塚建一

Tezuka Ken-ichi 手塚建一

TEZUKA Ken-ichi 手塚建一

手塚建一テヅカケンイチ

KENICHI Tezuka 手塚建一

手塚健一テヅカケンイチ

TEZUKA Kenichi 手塚建一

[Book] 再生医療叢書　第８巻2012