Hirokawa Makoto 廣川誠

… Alternative Names

HIROKAWA Makoto 廣川誠

廣川誠ヒロカワマコト

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Researcher Number	50241667
Other IDs
Affiliation (based on the past Project Information) *help	2019: 秋田大学, 医学系研究科, 教授 2015 – 2017: 秋田大学, 医学(系)研究科(研究院), 教授 2010 – 2012: 秋田大学, 医学部, 准教授 2002 – 2004: 秋田大学, 医学部, 講師 1996 – 2000: 秋田大学, 医学部, 助手 1993 – 1994: 秋田大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Hematology / 内科学一般 / Basic Section 54010:Hematology and medical oncology-related / Laboratory medicine / Hematology
Keywords	Principal Investigator CDR3 / T cell receptor / Leukemia / Allogeneic BMT / Clone / peripheral expansion / T細胞抗原受容体 / repertoire / GVHD / レパートリー … More / T細胞受容体 / 骨髄移植 / 赤芽球癆 / 標的治療 / ゲノム編集 / 機能解析 / 遺伝子変異 / 免疫抑制療法 / 体細胞変異 / 骨髄系腫瘍関連遺伝子 / 再発・難治性 / 後天性赤芽球癆 / リンパ系腫瘍 / ハイスループット・レパトア解析 / 次世代シーケンサー / NGS / レパトア / B細胞抗原受容体 / Bリンパ球 / 特発性血小板減少性紫斑病 / clone / immunodeficiency / T-cell regeneration / hematopoietic stem cell transplantation / T-cell receptor / 造血幹細胞移植 / クローン / 免疫不全症 / T細胞再構築 / 造血細胞移植 / complications / marrow transplantation / T細胞 / 移植合併症 / 骨髄不全症候群 / γδT細胞 / 慢性 / 後天性 / 細胞接着分子 / 血管内皮細胞 / NF-kB / Raji / HL-60 / ceramide / TNF-α receptor / TNF-α / BB1 / B7 / CD28 / 免疫寛容 / 同種 / 接着分子 Less

後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発Principal Investigator
- Principal Investigator
  
  廣川誠
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Akita University
Pathophysiology and targeted treatment of autoimmune hematological diseases based on the next generation high-throughput TCR/BCR repertoire analysisPrincipal Investigator
- Principal Investigator
  
  Hirokawa Makoto
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Akita University
Role for γδT lymphocytes in autoimmune bone marrow failure syndromePrincipal Investigator
- Principal Investigator
  
  HIROKAWA Makoto
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Akita University
STRUCTURE OF TCR ON TLYMPHOCYTES HARNESSING GRAFT-VERSUS-LEUKEMIA EFFECTPrincipal Investigator
- Principal Investigator
  
  HIROKAWA Makoto
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Akita University
MONITORING OF T-CELL RESEPTOR COMPLEMENTARITY-DETERMINIG REGION 3(CDR3)DIVERSITY AFTER HUMAN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATIONPrincipal Investigator
- Principal Investigator
  
  HIROKAWA Makoto
- Project Period (FY)
  1998 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  AKITA UNIVERSITY SCHOOL OF MEDICINE
Reconstitution of T cell receptor repertoire after human allogeneic bone marrow transplantationPrincipal Investigator
- Principal Investigator
  
  HIROKAWA Makoto
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Akita University
サイトカインおよびセカンドメッセンジャーによる腫瘍性幹細胞増殖抑制に関する研究Principal Investigator
- Principal Investigator
  
  廣川誠
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Akita University
細胞接着分子の修飾による同種抗原特異的免疫寛容の誘導Principal Investigator
- Principal Investigator
  
  廣川誠
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  内科学一般
- Research Institution
  Akita University

All 2019 2018 2017 2016 2015 2013 2012 2011 2010 2003

All Journal Article Presentation Book

[Book] 赤芽球癆．血液専門医テキスト第3版。日本血液学会（編）2019
- Author(s)
  廣川　誠
- Total Pages
  2
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19K08856
[Book] 赤芽球癆，今日の治療指針2019年版．福井次矢（編）2019
- Author(s)
  廣川　誠
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19K08856
[Book] 赤芽球癆．未来型血液治療学．小松則夫（編）2019
- Author(s)
  廣川　誠
- Total Pages
  11
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-19K08856
[Book] 赤芽球癆．1336専門家による私の治療. 2017-18年度版（猿田亨男編）2017
- Author(s)
  廣川　誠
- Publisher
  日本医事新報社
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 赤芽球癆．血液疾患最新の治療（小澤敬也編）2017
- Author(s)
  廣川　誠
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 赤芽球癆. 貧血症診断と治療のABC125（桐戸敬太編)2017
- Author(s)
  廣川　誠
- Publisher
  最新医学社
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 赤芽球癆、血液科研修ノート（永井良三、神田善伸編）2016
- Author(s)
  3)廣川　誠
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 慢性赤芽球癆の病態と治療、Annual Review2016血液（高久史麿、他編）2016
- Author(s)
  廣川　誠
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 今日の治療指針20152015
- Author(s)
  廣川　誠
- Total Pages
  1973
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 最新ガイドライン準拠血液疾患診断・治療指針2015
- Author(s)
  廣川　誠
- Total Pages
  560
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 免疫症候群　第2版Ⅰ（その他の免疫疾患を含めて）2015
- Author(s)
  廣川誠，澤田賢一
- Total Pages
  931
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 血液専門医テキスト改訂第2版2015
- Author(s)
  廣川　誠
- Total Pages
  584
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] ブラッシュアップ骨髄不全症2015
- Author(s)
  廣川　誠
- Total Pages
  193
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K08639
[Book] 難治性貧血の参照ガイド:赤芽球癆2011
- Author(s)
  廣川誠、澤田賢一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 専門医のための薬物療法Q&A血液(改訂第2版):赤芽球癆2011
- Author(s)
  廣川誠、澤田賢一
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 赤芽球癆.体専門医のための薬物療法Q&A血液(改訂第2版)(小松則夫、片山直之、他編)2011
- Author(s)
  廣川誠、澤田賢一
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 赤芽球癆.難治性貧血の参照ガイド.(難治性貧血の参照ガイド編集委員会編)2011
- Author(s)
  廣川誠、澤田賢一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 今日の治療指針2010:赤芽球癆2010
- Author(s)
  廣川誠
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 看護学テキストNICE疾病と治療II:再生不良性貧血・赤芽球癆2010
- Author(s)
  藤島直仁、廣川誠、澤田賢一
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 今日の治療指針2010:赤芽球癆2010
- Author(s)
  廣川誠
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 血液診療エキスパート:赤芽球癆(後天性)2010
- Author(s)
  廣川誠
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22591024
[Book] 血液診療エキスパート:赤芽球瘍(後天性)2010
- Author(s)
  廣川誠
- Total Pages
  2
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4?28/IGHJ4 gene in primary immune thrombocytopenia2019
- Author(s)
  Hirokawa Makoto、Fujishima Naohito、Togashi Masaru、Saga Akiko、Omokawa Ayumi、Saga Tomoo、Moritoki Yuki、Ueki Shigeharu、Takahashi Naoto、Kitaura Kazutaka、Suzuki Ryuji
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 8645-8645
- DOI
  10.1038/s41598-019-45264-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08856
[Journal Article] Comparison of outcomes of allogeneic transplantation for primary myelofibrosis among hematopoietic stem cell source groups.2019
- Author(s)
  Murata M, Takenaka K, Uchida N, Ozawa Y, Ohashi K, Kim SW, Ikegame K, Kanda Y, Kobayashi H, Ishikawa J, Ago H, Hirokawa M, Fukuda T, Atsuta Y, Kondo T.
- Journal Title
  
  Biology of Blood and Marrow Transplantation
  
  Volume: 25 Issue: 8 Pages: 1536-1543
- DOI
  10.1016/j.bbmt.2019.02.019
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08321, KAKENHI-PROJECT-18H02840, KAKENHI-PROJECT-19K08856
[Journal Article] HLA discrepancy between graft and host rather than that graft and first donor impact the second transplant outcome.2018
- Author(s)
  Maeda Y, Ugai T, Kondo E, Ikegame K, Murata M, Uchida N, Miyamoto T, Takahashi S, Ohashi K, Nakamae H, Fukuda T, Onizuka M, Eto T, Ota S, Hirokawa M, Ichinohe T, Atsuta Y, Kanda Y, Kanda J.
- Journal Title
  
  Haematologica.
  
  Volume: Dec.6 Issue: 5 Pages: 1055-1061
- DOI
  10.3324/haematol.2018.204438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09866, KAKENHI-PROJECT-19K08856
[Journal Article] 成人大球性貧血の診断2017
- Author(s)
  廣川　誠
- Journal Title
  
  Medical Practice
  
  Volume: 34 Pages: 1213-1213
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Diagnosis and treatment of macrocytic anemias in adults2017
- Author(s)
  Nagao, T., Hirokawa, M.
- Journal Title
  
  J Gen Fam Med
  
  Volume: 18 Issue: 5 Pages: 200-204
- DOI
  10.1002/jgf2.31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] 後天性赤芽球癆の特徴と治療の実際2017
- Author(s)
  廣川　誠
- Journal Title
  
  新薬と臨床
  
  Volume: 66 Pages: 62-67
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Reduced-intensity conditioning allogeneic hematopoietic cell transplantation for younger patients with acute myeloid leukemia: a registry-based study2017
- Author(s)
  Yanada, M., Kurosawa, S., Kobayashi, T., Ozawa, Y., Kanamori, H., Kobayashi, N., Sawa, M., Nakamae, H., Uchida, N., Hashimoto, H., Fukuda, T., Hirokawa, M., Atsuta, Y., Yano, S.
- Journal Title
  
  Bone Marrow Transplant
  
  Volume: 52 Issue: 6 Pages: 818-824
- DOI
  10.1038/bmt.2016.358
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] 赤芽球癆：疾患概念・病因・病態2017
- Author(s)
  廣川　誠
- Journal Title
  
  日本臨牀
  
  Volume: 75 Pages: 431-436
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] 脱顆粒を伴う好酸球の非アポトーシス細胞死2016
- Author(s)
  植木重治，本田耕平，廣川　誠
- Journal Title
  
  アレルギーの臨床
  
  Volume: 36 Pages: 71-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] The effect of hepatocyte growth factor on secretory functions in human eosinophils2016
- Author(s)
  Yamauchi Y, Ueki S, Konno Y, Ito W, Takeda M, Nakamura Y, Nishikawa J, Moritoki Y, Omokawa A, Saga T, Hirokawa M
- Journal Title
  
  Cytokine
  
  Volume: 88 Pages: 45-50
- DOI
  10.1016/j.cyto.2016.08.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Cytosine-phosphorothionate- guanine oligodeoxynucleotides exacerbates hemophagocytosis by inducing tumor necrosis factor-α production in mice after bone marrow transplanation.2016
- Author(s)
  Liu J, Guo YM, Onai N, Ohyagi H, Hirokawa M, Takahashi N, Tagawa H, Ubukawa K, Kobayahi I, Tezuka H, Minamiya Y, Ohteki T, and Sawada K.
- Journal Title
  
  Biol Blood Marrow Transplant 2015
  
  Volume: 印刷中 Issue: 4 Pages: 627-636
- DOI
  10.1016/j.bbmt.2015.12.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15150, KAKENHI-PUBLICLY-15H01485, KAKENHI-PUBLICLY-15H01508, KAKENHI-PROJECT-26253029, KAKENHI-PROJECT-15H04717, KAKENHI-PROJECT-25460586, KAKENHI-PROJECT-26461439, KAKENHI-PROJECT-15K08639
[Journal Article] Possible involvement of reusable towels in the high rate of Bacillus species-positive blood cultures in Japanese hospitals2016
- Author(s)
  Saito N, Kondo J, Haruki S, Itoga M, Yamamoto A, Kim ura M, Inoue F, Kobayashi M, Tsutaya S, Kojima K, Ueki S, Hirokawa M, Kayaba H
- Journal Title
  
  J Infect Chemother
  
  Volume: 22 Issue: 2 Pages: 96-101
- DOI
  10.1016/j.jiac.2015.11.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] 臨床検査技師のスキルアップを考える. 臨床病理 64(1)，89-952016
- Author(s)
  小林則子，鎌田由美子，富谷陽子，菊地優子，面川　歩，嵯峨知生，植木重治，廣川誠
- Journal Title
  
  臨床病理
  
  Volume: 64 Pages: 89-95
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Eosinophil extracellular trap cell death-derived DNA traps: Their presence in secretions and functional attributes.2016
- Author(s)
  Ueki S, Konno Y, Takeda M, Moritoki Y, Hirokawa M, Matsuwaki Y, Honda K, Ohta N, Yamamoto S, Takagi Y, Wada A, Weller PF.
- Journal Title
  
  J Allergy Clin Immunol.
  
  Volume: 137 Issue: 1 Pages: 258-267
- DOI
  10.1016/j.jaci.2015.04.041
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460670, KAKENHI-PROJECT-25462675, KAKENHI-PROJECT-15K08639
[Journal Article] 好酸球性炎症の新しい機序2016
- Author(s)
  植木重治,中村由夏,廣川　誠
- Journal Title
  
  アレルギーの臨床
  
  Volume: 36 Pages: 1349-1352
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Eosinophil ETosis and DNA Traps: a New Look at Eosinophilic Inflammation.2016
- Author(s)
  Ueki S, Tokunaga T, Fujieda S, Honda K,　et al
- Journal Title
  
  Curr Allergy Asthma Rep.
  
  Volume: 16(8) Issue: 8 Pages: 1-17
- DOI
  10.1007/s11882-016-0634-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10776, KAKENHI-PROJECT-15K08639
[Journal Article] Progress in the clinical management of pure red cell aplasia and future prospects2016
- Author(s)
  廣川　誠
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 57 Issue: 2 Pages: 110-116
- DOI
  10.11406/rinketsu.57.110
- NAID
  130005132709
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Impact of age on outcomes of allogeneic hematopoietic stem cell transplantation with reduced intensity conditioning in elderly patients with acute myeloid leukemia2016
- Author(s)
  Aoki　J，Kanamori　H，Tanaka　M，Yamasaki　S，Fukuda　T，Ogawa H，Iwato K，Ohashi K，Okumura　H，Onizuka　M，Maesako　Y，Teshima T，Kobayashi　N，Morishima　Y，Hirokawa　M，Atsuta　Y，Yano　S，Takami　A
- Journal Title
  
  Am J Hematol
  
  Volume: 91 Issue: 3 Pages: 302-307
- DOI
  10.1002/ajh.24270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639, KAKENHI-PROJECT-15K09513
[Journal Article] 赤芽球癆の発症機序と診断の進めかた2016
- Author(s)
  廣川　誠
- Journal Title
  
  Medical Practice
  
  Volume: 33 Pages: 1413-1417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] L-アスパラギナーゼ治療中のアンモニア測定に関する検査室の経験：採血管内での上昇について2016
- Author(s)
  高橋　縁，藤田美好，植木重治，廣川　誠
- Journal Title
  
  臨床化学
  
  Volume: 45 Pages: 269-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Long-term outcome of patients with acquired chronic pure red cell aplasia (PRCA) following immunosuppressive therapy: a final report of the nationwide cohort study in 2004/2006 by the Japan PRCA collaborative study group.2015
- Author(s)
  Hirokawa M, Sawada K, Fujishima N, Teramura M, Bessho M, Dan K, Tsurumi H, Nakao S, Urabe A, Fujisawa S, Yonemura Y, Kawano F, Oshimi K, Sugimoto K, Matsuda A, Karasawa M, Arai A, Komatsu N, Harigae H, Omine M, Ozawa K, Kurokawa M; PRCA Collaborative Study Group.
- Journal Title
  
  Br J Haematol.
  
  Volume: in press Issue: 6 Pages: 879-886
- DOI
  10.1111/bjh.13376
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390247, KAKENHI-PROJECT-15K08639, KAKENHI-PROJECT-15K09468
[Journal Article] 再生不良性貧血と赤芽球癆の病態と治療2015
- Author(s)
  廣川誠，藤島直仁，面川歩，植木重治
- Journal Title
  
  日本内科学会雑誌
  
  Volume: 104 Pages: 1405-1413
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Diagnosis and management of pure red cell aplasia2015
- Author(s)
  廣川誠
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 56 Issue: 10 Pages: 1922-1931
- DOI
  10.11406/rinketsu.56.1922
- NAID
  130005103308
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-15K08639
[Journal Article] Functional ana- lysis of free fatty acid receptor GPR120 in human eosinophils: implications in metabolic homeostasis.2015
- Author(s)
  Konno, Y., Ueki, S., Takeda, M., Kobayashi, Y., Tamaki, M., Moritoki, Y., Oyamada, H., Itoga, M., Kayaba, H., Omokawa, A., Hirokawa, M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0120386-e0120386
- DOI
  10.1371/journal.pone.0120386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08639, KAKENHI-PROJECT-25460670
[Journal Article] G-Protein-Coupled Estrogen Receptor Agonist Suppresses Airway Inflammation in a Mouse Model of Asthma through IL-10.2015
- Author(s)
  Itoga, M., Konno, Y., Moritoki, Y., Saito, Y., Ito, W., Tamaki, M., Kobayashi, Y., Kayaba, H., Kikuchi, Y., Chihara, J., Takeda, M., Ueki, S., Hirokawa, M.
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: e0123210-e0123210
- DOI
  10.1371/journal.pone.0123210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08639, KAKENHI-PROJECT-25460670
[Journal Article] CDR3-independent expansion of Vδ1 T lymphocytes in acquired chronic pure red cell aplasia2013
- Author(s)
  Michishita Y, Hirokawa M, Fujisima N, Abe Y, Fujishima M, Guo Y-M, Ubukawa K, Liu J, Yoshioka T, Kameoka Y, Saitoh H, Tagawa H, Takanashi N, Sawada K
- Journal Title
  
  Immunol Lett
  
  Volume: 150 Pages: 23-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] Enucleation of human erythroblasts involves nonmuscle myosin IIB2012
- Author(s)
  Ubukawa K, Guo YM, Takahashi M, Hirokawa M, Michishita Y, Nara M, Tagawa H, Takahashi N, Komatsuda A, Nunomura W, Takakuwa Y, Sawada K
- Journal Title
  
  Blood
  
  Volume: 119 Pages: 1036-1044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] 低リスクMDSに対するレナリドミドの効果2011
- Author(s)
  廣川誠
- Journal Title
  
  血液内科
  
  Volume: 63 Pages: 184-189
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] 専門医に紹介すべき貧血:赤芽球癆(病態と診断)2011
- Author(s)
  廣川誠
- Journal Title
  
  Mebio
  
  Volume: 28 Pages: 64-70
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] Age-associated alteration of γδ T cell repertoire and different profiles of activation-induced death of V1 and Vδ2 T cells.2011
- Author(s)
  Michishita Y, Hirokawa M, Guo YM, Abe Y, Liu J, Ubukawa K, Fujishima N, Fujishima M, Yoshioka, T Kameoka Y, Saito H, Tagawa H, Takahashi N, Sawada K
- Journal Title
  
  Int J Hematol
  
  Volume: 94 Pages: 230-240
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] ESA(erythropoiesis-stimulating agents)とがん性貧血2011
- Author(s)
  澤田賢一、廣川誠
- Journal Title
  
  腎と透析
  
  Volume: 71 Pages: 276-278
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] CpG-ODN 2006 and human parvovirus B19 genome consensus sequences selectively inhibit growth and development of erythroid progenitor cells2010
- Author(s)
  Guo YM, Ishii K, Hirokawa M, Tagawa H, Ohyagi H, Michishita Y, Ubukawa K, Yamashita J, Ohteki T, Onai N, Kawakami K, Xiao W, Sawada K
- Journal Title
  
  Blood
  
  Volume: 115 Pages: 4569-4579
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] Delayed addition of tumor necrosis factor (TNF) antagonists inhibits the generation of CD11c+ dendritic cells derived from CD34+ cells exposed to TNF-α.2010
- Author(s)
  Guo YM, Hirokawa M, Takahashi N, Fujishima M, Fujishima N, Komatsuda A, Tagawa H, Ohyagi H, Michishita Y, Ubukawa K, Hebiguchi M, Xiao W, Sawada K
- Journal Title
  
  Int J Hematol
  
  Volume: 91 Pages: 61-68
- NAID
  10026110617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] 腫瘍随伴症候群:自己免疫様疾患2010
- Author(s)
  廣川誠
- Journal Title
  
  癌と化学療法
  
  Volume: 37 Pages: 980-983
- Data Source
  KAKENHI-PROJECT-22591024
[Journal Article] T-cell repertoire regeneration after human allogeneic hematopoietic stem cell transplantation : current concept and future direction2003
- Author(s)
  Hirokawa M, et al.
- Journal Title
  
  Recent Research Development in Immunology, Research Signpost, Kerara 5
  
  Pages: 151-157
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14570960
[Journal Article] T-cell repertoire regeneration after human allogeneic hematopoietic stem cell transplantation : current concept and future direction.2003
- Author(s)
  Hirokawa M, et al.
- Journal Title
  
  Recent Research Development in Immunology(Research Signpost, Kerara) 5
  
  Pages: 151-157
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14570960
[Presentation] 後天性赤芽球癆における骨髄性腫瘍関連遺伝子の体細胞変異に関する研究（PRCA-NGS2017）2019
- Author(s)
  幸丸純貴,小代田宗一,久場敬二,藤島直仁,嵯峨知生,面川　歩,植木重治,石田文宏,中尾眞二,松田　晃,太田晶子,通山　薫,鈴木隆二,三谷絹子,廣川　誠
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08856
[Presentation] High-throughput sequencing of IgG B-cell receptors reveals frequent usage of the rearranged IGHV4/IGHJ4 gene in primary immune thrombocytopenia in adults2017
- Author(s)
  Fujishima, N., Togashi, M., Hasegawa, R., Watanabe, K., Saga, A., Omokawa, A., Saga, T., Ueki, S., Takahashi, N., Kitaura, K., Suzuki, R., Hirokawa, M.
- Organizer
  59th Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] 後天性慢性赤芽球癆の長期予後を明らかにするための多施設共同前向き観察研究(PRCA2016)中間報告2017
- Author(s)
  廣川　誠，藤島直仁，澤田賢一，張替秀郎，松田　晃，小松則夫，通山　薫，米村雄士，中尾眞二，齋藤明子，松村　到，荒井俊也，黒川峰夫
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Identification of Adverse Risk Factors for Survival in Acquired Pure Red Cell Aplasia Receiving Immunosuppressive Therapy By the Japan PRCA2004/2006 Study and Introduction to the New Cohort Study PRCA20162017
- Author(s)
  Hirokawa, M., Fujishima, N., Teramura, M., et al.
- Organizer
  59th Annual Meeting of American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] ヒト好酸球に対する肝細胞増殖因子(HGF)の細胞外分泌能とETosisへの影響2016
- Author(s)
  山内由美子，植木重治，中村由夏，今野泰典，面川歩，守時由起，伊藤亘，竹田正秀，嵯峨知生，廣川誠
- Organizer
  第56回日本呼吸器学会
- Place of Presentation
  京都
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] 5)Itoga M, Konno Y，Moritoki Y，Saito Y，Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M2016
- Author(s)
  Itoga M, Konno Y，Moritoki Y，Saito Y，Ito W, Tamaki M, Kobayashi Y, Kayaba H, Kikuchi Y, Chihara J, Takeda M, Ueki S, Hirokawa M
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Comparison of the number of genome-wide single nucleotide polymorphisms (SNPs) among epidemiologically-related and -unrelated methicillin-resistant Staphylococcus aureus (MRSA) isolates of indistinguishable genotype by PCR-based open-reading frame typing (POT) kit2016
- Author(s)
  1)Saga T, Tatsuko R, Aoki K, Omokawa A, Moritoki Y, Shimizu-Saga A, Kobayashi N, Ueki S, Ishii Y, Tateda K, and Hirokawa M
- Organizer
  IDWeek 2016
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-10-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] 好酸球と好中球のETosisにより生じるDNA trapsの差異2016
- Author(s)
  植木重治，今野泰典，竹田正秀，中村由夏，守時由起，面川　歩，嵯峨知生，廣川　誠，Peter Weller
- Organizer
  第56回日本呼吸器学会
- Place of Presentation
  京都
- Year and Date
  2016-04-08
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] 好酸球性ムチンの粘性はなぜ高いのか－好酸球と好中球DNA trapsの差異2016
- Author(s)
  植木重治，中村由夏，今野泰典，竹田正秀，守時由起，廣川　誠，本田耕平，太田伸男，松脇良典，Peter Weller
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Recent updates in acquired pure red cell aplasia in the　adults2016
- Author(s)
  Hirokawa M
- Organizer
  Taiwan-Japan Hematology Forum HST-EHA Joint Symposium
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2016-04-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] TLR9 signaling exerts HPS in BMT mice and is effectively treated through TNF-α inhibition2015
- Author(s)
  Liu, J., Guo, Y., Hirokawa, M., Takahasi, N., Ubukawa, K., Kobayashi, I., Minamiya, Y., Tezuka, H., Onai, N., Ohteki, T., Sawada, K.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] 赤芽球癆の診断と治療（教育講演）2015
- Author(s)
  廣川誠
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Invited
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Impact of donor source on allogeneic HSCT outcomes for patients with CMML.2015
- Author(s)
  Itonaga, H., Aoki, K., Aoki, J., Ishiyama, K., Ishikawa, T., Uchida, N., Hoshino, T., Ohashi, K., Kurokawa, M., Ozawa, Y., Matsuoka, K., Yuiri, T., Hirokawa, M., Morishima, Y., Kato, K., Atsuta, Y., Miyazaki, Y.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Long-term outcome of patients with acquired chronic PRCA following immunosuppressive therapy2015
- Author(s)
  Hirokawa, M., Sawada, K., Fuishima, N., Teramura, M., Bessho, M., Dan, K., Tsurumi, H., Nakao, S., Urabe, A., Fujisawa, S., Yonemura, Y., Kawano, F., Oshimi, K., Sugumoto, K., Matsuda, A., Karasawa, M., Arai, A., Komatsu, N., Harigae, H., Omine, M., Ozawa, K., Kurokawa, M.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Influence of CYP3A5 gene polymorphisms on pharmacokinetics of modified-release tacrolimus.2015
- Author(s)
  Yamashita, T., Fujishima, N., Miura, M., Niioka, T., Abumiya, M., Nara, M., Fujishima, M., Kameoka, Y., Hirokawa, M., Takahashi, N.
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-15K08639
[Presentation] Efficacy and long-term outcome of intervention for pure red cell aplasia (PRCA) following allogeneic hematopoietic stem cell transplantation from major ABO-incompatible donors2011
- Author(s)
  Hirokawa M, Sawada K, Fujishima N, Fukuda T, Akiyama H, Imamura M, Adachi S, Urabe A, Okamoto S, Suzuki R, Tanimoto M, Nakao S, ugita M, Morishima Y, Sakamaki H, Ozawa K
- Organizer
  16th Congress of European Hematology Association
- Place of Presentation
  London
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] CDR3-independent expansion of Vδ1 γδ T lymphocytes and depletion of Vδ2 T cells are unique features in acquired pure red cell aplasia2011
- Author(s)
  Michishita Y, Hirokawa M, Fujishima N, Abe Y, Fujishima M, Guo Y-M, Ubukawa K, Liu J, Yoshioka T, Kameoka Y, Saitoh H, Tagawa H, Takahashi N, Sawada K
- Organizer
  53rd American Society of Hematology Annual Meeting and Exposition
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Efficacy and long-term outcome of intervention for pure red cell aplasia (PRCA) following allogeneic hematopoietic stem cell transplantation from major ABO-incompatible donors2011
- Author(s)
  Hirokawa M, et al.
- Organizer
  16th Congress of European Hematology Association
- Place of Presentation
  Londonm UK
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Major ABO不適合ドナーからの同種造血幹細胞移植後赤芽球癆に対する治療介入の効果と長期予後2011
- Author(s)
  廣川誠, 他
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Alteration of γδ T-cell repertoire in acquired chronic pure red cell aplasia2010
- Author(s)
  Hirokawa M, Michishita Y, Fujishima N, Fujishima M, Guo YM, Kameoka Y, Saitoh H, Tagawa H, Takahashi N, Sawada K
- Organizer
  1^<st> JSH International Symposium 2010
- Place of Presentation
  Akita, Japan
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] 後天性慢性赤芽球癆におけるγδT細胞レパートリーの変化とそのメカニズム2010
- Author(s)
  道下吉広、安倍由紀子,藤島直仁,藤島眞澄,奈良美保、郭永梅,鵜生川久美,斎藤宏文,高橋直人,廣川 ,澤田賢一
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Alteration of γδ T-cell repertoire in acquired chronic pure red cell aplasia2010
- Author(s)
  Hirokawa M, et al.
- Organizer
  JSH International Symposium 2010
- Place of Presentation
  Akita, Japan
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] Combined challenge of TLR9- and Nod1-ligands induces hemophagocytic sundrome in mice2010
- Author(s)
  Onai N, Oyagi H, Hirokawa M, Sawada K, Ohteki T
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, August
- Data Source
  KAKENHI-PROJECT-22591024
[Presentation] CpG-ODN 2006 and human parvovirus B19 genome consensus sequences selectively inhibit growth and development of erythroid progenitor cells2010
- Author(s)
  Guo Y-M, Ishii K, Hirokawa M, Tagawa H, Ohyagi H, Michishita Y, Ubukawa K, Yamashita J, Ohteki T, Onai N, Kawakami K, Xiao WG, Sawada K
- Organizer
  15^<th> Congress of the European Hematology Association
- Place of Presentation
  Barcelona
- Data Source
  KAKENHI-PROJECT-22591024

1. 鈴木隆二 (70373470)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
2. FUJISHIMA Naohito (70422152)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
3. KAWABATA Yoshinari (70361227)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SAWADA Kenichi (90226069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
5. FUJISHIMA Masumi (80422153)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
6. KITAURA Kazutaka (00518136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. MATSUTANI Takaji (70372290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 久場敬司 (10451915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 小松久美 (70646554)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石田文宏 (80311695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 北林淳

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 小内伸幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 樗木俊聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 植木重治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 本田耕平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 小澤敬也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 村田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 高橋聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirokawa Makoto 廣川 誠

HIROKAWA Makoto 廣川 誠

廣川 誠 ヒロカワ マコト

Research Projects

Research Products

Co-Researchers

後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発Principal Investigator

Principal Investigator

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Review Section

Research Institution

Pathophysiology and targeted treatment of autoimmune hematological diseases based on the next generation high-throughput TCR/BCR repertoire analysisPrincipal Investigator

Principal Investigator

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Research Institution

Role for γδT lymphocytes in autoimmune bone marrow failure syndromePrincipal Investigator

Principal Investigator

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STRUCTURE OF TCR ON TLYMPHOCYTES HARNESSING GRAFT-VERSUS-LEUKEMIA EFFECTPrincipal Investigator

Principal Investigator

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Research Institution

MONITORING OF T-CELL RESEPTOR COMPLEMENTARITY-DETERMINIG REGION 3(CDR3)DIVERSITY AFTER HUMAN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATIONPrincipal Investigator

Principal Investigator

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Reconstitution of T cell receptor repertoire after human allogeneic bone marrow transplantationPrincipal Investigator

Principal Investigator

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サイトカインおよびセカンドメッセンジャーによる腫瘍性幹細胞増殖抑制に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

細胞接着分子の修飾による同種抗原特異的免疫寛容の誘導Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

[Book] 赤芽球癆．血液専門医テキスト第3版。日本血液学会（編）2019

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[Book] 赤芽球癆，今日の治療指針2019年版．福井次矢（編）2019

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[Book] 赤芽球癆．未来型血液治療学．小松則夫（編）2019

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[Book] 赤芽球癆．1336専門家による私の治療. 2017-18年度版（猿田亨男編）2017

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[Book] 赤芽球癆．血液疾患最新の治療（小澤敬也編）2017

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Data Source

[Book] 赤芽球癆. 貧血症 診断と治療のABC125（桐戸敬太編)2017

Author(s)

Publisher

Hirokawa Makoto 廣川誠

HIROKAWA Makoto 廣川誠

廣川誠ヒロカワマコト

[Book] 赤芽球癆. 貧血症診断と治療のABC125（桐戸敬太編)2017

[Book] 免疫症候群　第2版Ⅰ（その他の免疫疾患を含めて）2015