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mizokami atsushi  溝上 敦

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MIZOKAMI Atsushi  溝上 敦

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Researcher Number 50248580
Other IDs
External Links
Affiliation (Current) 2025: 金沢大学, 医学系, 教授
Affiliation (based on the past Project Information) *help 2016 – 2023: 金沢大学, 医学系, 教授
2013 – 2016: 金沢大学, 医学系, 准教授
2008 – 2012: 金沢大学, 附属病院, 講師
2011: 金沢大学, 大学病院, 講師
2004 – 2007: Kanazawa University, Hospital, Lecturer, 医学部附属病院, 講師
2001 – 2004: 金沢大学, 医学部附属病院, 助手
1996 – 1997: 産業医科大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Urology / Urology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Except Principal Investigator
Urology / Basic Section 56030:Urology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Urology
Keywords
Principal Investigator
前立腺癌 / prostate cancer / COX-2 / VEGF / cDNA microarray / 去勢抵抗性前立腺癌 / lipoxygenase / ホルモン非依存性 / promoter / TPA … More / 去勢抵抗性 / 間葉上皮移行 / 肝間質細胞 / 肝転移 / Taxane系耐性前立腺癌 / taxane系耐性前立腺癌 / クロストーク / タキサン耐性 / 薬剤耐性 / フラボノイド / 抗癌剤耐性 / フラボノイド誘導体 / 癌細胞間作用 / 微小環境 / androgen-dependent / ホルモン依存性 / 抗癌剤抵抗性 / リポキシゲナーゼ / サイクロオキシナーゼ2 / 前立腺 / relapse / androgen dependency / 遺伝子治療 / 再燃 / renal cell carcinoma / プロモーター / 腎癌 / DHEA / アンドロゲン受容体 / 2'-hydroxyflavanone / AR-V7 / 誘導体 / 2’-hydroxyflavanone / デキサメサゾン / CAMKK2 / アンドロゲン感受性 / アンドロゲン … More
Except Principal Investigator
前立腺癌 / ケモカイン / 去勢抵抗性前立腺癌 / 間質細胞 / prostate cancer / 微小環境 / NF-κB / 再燃前立腺癌 / アンドロゲン / パクリタキセル耐性 / 免疫チェックポイント阻害薬 / 腎細胞癌 / ジテルペン / 去勢抵抗性 / 腫瘍免疫 / アンドロゲン受容体 / LNCaP / real-time PCR / STS / AZF / Her-2 / 骨転移 / ドセタキセル耐性 / アンドロゲン / 共培養 / SOD3 / エストロゲン / 遺伝子治療 / 再燃 / 腫瘍随伴マクロファージ / 抗炎症作用 / FGF / KRAS / ダブルネガティブ去勢抵抗性 / コホート 研究 / 枯葉剤 / ベトナム / ステロイドホルモン / 低体重出生児 / 二次性徴 / ダイオキシン / バイオマーカー / TCRレパトア / 免疫チェックポイント / リンパ節転移 / 内臓転移 / micro RNA / 遊走能 / マイクロRNA / コーヒー / タキサン抵抗性 / カバジタキセル耐性 / 耐性 / カバジタキセル / ドセタキセル / CRPC / 制御性T細胞 / 腫瘍随伴性マクロファージ / dominant negative / p65 / IκBa / androgen-dependent / androgen-independent / 分子標的創薬 / 転写制御因子 / アンドロゲン非依存性前立腺癌 / 分子標的薬 / ドミナントネガティブ / デコイ / 再燃メカニズム / ホルモン不応性前立腺癌 / Spermatogenesis / genome / palindrome / male infertility / Y chromosome / 精子形成遺伝子 / 無精子症 / 特発性男性不妊症 / 精子形成障害 / ゲノム / パリンドローム / 男性不妊症 / Y染色体 / tyrosine kinase inhibitor / bisphosphonate / bone metastasis / relapse / 胃転移 / 分子標的治療 / 分子様的治療 / HER-2 / Bisphosphonate / hTERT / チロシンキナーゼ阻害剤 / ビスフォスフォネート / 癌微小環境 / アンドロゲン生合成 / アンドロゲン非依存性前立腺癌細胞 / アンドロゲン感受性前立腺癌細胞 / アンドロゲン受容体 / フラボノイド誘導体 / クロストーク / カバジタキセル耐性株 / 腎癌 / 植物フラボノイド / ノスカピン / docetaxel / flavonoids / renal cell cancer / Noscapine / cDNA microarray / フラボノイド / SPARC / テストステロン / 酸性ホスファターゼ / トランスポゾン / アロマターゼ / 内因性レトロウイルス / 前立腺がん / シグナル伝達系 / ERE / AR / 転写活性 / リガンド / ER / SCIDマウス / シグナル伝達 / エストロゲン受容体 / TGFβ / CTEN / トラニラスト / DHEA / ワクチン療法 / 分子シャペロン / 免疫治療 / ORP150 / 膀胱癌 Less
  • Research Projects

    (29 results)
  • Research Products

    (64 results)
  • Co-Researchers

    (23 People)
  •  腎癌における腫瘍随伴マクロファージを標的としたコーヒージテルペンの抗腫瘍効果

    • Principal Investigator
      角野 佳史
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kanazawa University
  •  KRAS活性を介したダブルネガティブ去勢抵抗性前立腺癌進展機構の解明

    • Principal Investigator
      泉 浩二
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kanazawa University
  •  The mechanism of AR signaling-independent prostate cancerPrincipal Investigator

    • Principal Investigator
      Mizokami Atsushi
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Kanazawa University
  •  Investigation of predictive factors for efficacy of immune heckpoint inhibitor in renal cell carcinoma

    • Principal Investigator
      Kadono Yoshifumi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kanazawa University
  •  Cohort study on herbicide/dioxins and secondary sexual characteristic or low weight infants in Vietnam

    • Principal Investigator
      城戸 照彦
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Kanazawa University
  •  Coffee diterpens inhibit prostate cancer progression

    • Principal Investigator
      IZUMI Kouji
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kanazawa University
  •  Androgen receptor signaling-controlled microRNA inhibits prostate cancer metastasis

    • Principal Investigator
      NOHARA Takahiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Kanazawa University
  •  Progression of prostate cancer bone metastasis by exosomal micro RNA regulated-chemokine

    • Principal Investigator
      NARIMOTO Kazutaka
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      St. Luke's International University
  •  The development of the innovative therapeutic drugs which targete crosstalk in the prostate cancer microenvironmentPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Induction of immune tolerance via CCL20 during inhibition of androgen/AR signaling

    • Principal Investigator
      IZUMI Kouji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Mechanism of docetaxel and cabazitaxel-resistance in castration-resistant prostate cancer

    • Principal Investigator
      KADONO Yoshifumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Elucidation of mechanisms of the prostate cancer progress in consideration of AR Axis / microenvironment and the construction of the innovative treatment strategy

    • Principal Investigator
      NAMIKI Mikio
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  The mechanisms of prostate cancer progression in bone metastasis microenvironment through CCL2 signaling

    • Principal Investigator
      NARIMOTO Kazutaka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Prevention of CRPC and application for docetaxel treatment using flavonoidsPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Effect of microenvironment on progression of CRPC and on docetaxel-resistance

    • Principal Investigator
      KADONO Yoshifumi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Solution of the molecular mechanism about proliferation / recurrence of the prostate cancer and the architecture of the comprehensive treatment strategy for he prostate cancer

    • Principal Investigator
      NAMIKI Mikio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Effect of Noscapine and its derivative, EM101, on renal cell cancer and their mechanisms

    • Principal Investigator
      MIYAGI Toru
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Identification of androgen-response genes related with the proliferation and development of proliferation-related marker in prostate cancerPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  The basic research for elucidation of molecular mechanism of the prostate cancer recurrence and the treatment strategy construction

    • Principal Investigator
      NAMIKI Mikio
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Comprehensive elucidation of estrogen receptor mediated signal pathways in hormone refractory prostate cancer

    • Principal Investigator
      KONAKA Hiroyuki
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  ゲノム病としての前立腺がん-内因性レトロウイルスとアンドロゲン調節領域-

    • Principal Investigator
      KOH Eitetsu (高 榮哲)
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Significance of NE-κB activation and therapeutic strategies for targeting its pathway in androgen-independent prostate cancer

    • Principal Investigator
      KONAKA Hiroyuki
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Identification of progression-related genes in prostate cancer and application to treatmentPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Basic research of gene targeting and molecular targeting therapy for relapse of prostate cancer

    • Principal Investigator
      NAMIKI Mikio
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Effect of cyclooxygenase-2 and lipoxygenase on progression of prostate cancerPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Analysis and detecction of polymorphism of palindrome complex on Y chmmosome in idiopathic male infertility

    • Principal Investigator
      KOH Eitetsu
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  小胞体分子シャペロンORP150を用いた膀胱癌に対する癌免疫治療の実験的検討

    • Principal Investigator
      NAMIKI Mikio
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Kanazawa University
  •  Identification of genes associated with relapse of prostate cancer and gene therapyPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kanazawa university
  •  Analysis of mechanism for VEGF expression in renal cell carcinomaPrincipal Investigator

    • Principal Investigator
      MIZOKAMI Atsushi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Unuversity of Occupational and Environmental Health

All 2022 2021 2020 2019 2018 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 2002

All Journal Article Presentation Patent

  • [Journal Article] Sarcopenia and Visceral Metastasis at Cabazitaxel Initiation Predict Prognosis in Patients With Castration-resistant Prostate Cancer Receiving Cabazitaxel Chemotherapy.2021

    • Author(s)
      Iwamoto H, Kano H, Shimada T, Naito R, Makino T, Kadomoto S, Yaegashi H, Shigehara K, Izumi K, Kadono Y, Mizokami A.
    • Journal Title

      In Vivo

      Volume: 35 Issue: 3 Pages: 1703-1709

    • DOI

      10.21873/invivo.12430

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09685, KAKENHI-PROJECT-21K16728
  • [Journal Article] Undesirable Status of Prostate Cancer Cells after Intensive Inhibition of AR Signaling: Post-AR Era of CRPC Treatment.2021

    • Author(s)
      Makino T, Izumi K, Mizokami A.
    • Journal Title

      Biomedicines

      Volume: 9 Issue: 4 Pages: 414-414

    • DOI

      10.3390/biomedicines9040414

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Journal Article] Anti-proliferative and anti-migratory properties of coffee diterpenes kahweol acetate and cafestol in human renal cancer cells2021

    • Author(s)
      Makino T, Izumi K, Hiratsuka K, Kano H, Shimada T, Nakano T, Kadomoto S, Naito R, Iwamoto H, Yaegashi H, Shigehara K, Kadono Y, Nakata H, Saito Y, Nakagawa-Goto K, Sakai N, Iwata Y, Wada T, Mizokami A.
    • Journal Title

      Sci Rep

      Volume: 11 Issue: 1 Pages: 675-675

    • DOI

      10.1038/s41598-020-80302-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08426, KAKENHI-PROJECT-19K09685, KAKENHI-PROJECT-20K09574
  • [Journal Article] Coffee diterpenes kahweol acetate and cafestol synergistically inhibit the proliferation and migration of prostate cancer cells.2019

    • Author(s)
      Iwamoto H, Izumi K*, Natsagdorj A, Naito R, Makino T, Kadomoto S, Hiratsuka K, Shigehara K, Kadono Y, Narimoto K, Saito Y, Nakagawa-Goto K, Mizokami A.
    • Journal Title

      Prostate

      Volume: 79 Issue: 5 Pages: 468-479

    • DOI

      10.1002/pros.23753

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11126
  • [Journal Article] C-C motif ligand 5 promotes migration of prostate cancer cells in the prostate cancer bone metastasis microenvironment.2018

    • Author(s)
      Urata S, Izumi K, Hiratsuka K, Maolake A, Natsagdorj A, Shigehara K, Iwamoto H, Kadomoto S, Makino T, Naito R, Kadono Y, Lin WJ, Wufuer G, Narimoto K, Mizokami A
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 3 Pages: 724-731

    • DOI

      10.1111/cas.13494

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11126
  • [Journal Article] Crosstalk Between Androgen-Sensitive and Androgen-Insensitive Prostate Cancer Cells2018

    • Author(s)
      YUTA TAKEZAWA, KOUJI IZUMI, KAZUAKI MACHIOKA, HIROAKI IWAMOTO, RENATO NAITO, TOMOYUKI MAKINO, SUGURU KADOMOTO, ARIUNBOLD NATSAGDORJ, YOSHIFUMI KADONO, EVAN T. KELLER, JIAN ZHANG and ATSUSHI MIZOKAMI
    • Journal Title

      Anticancer Research

      Volume: 38 Pages: 2045-2055

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04325
  • [Journal Article] Establishment and characterization of two cabazitaxel-resistant prostate cancer cell lines2018

    • Author(s)
      Kazuaki Machioka, 1Kouji Izumi, 1Yoshifumi Kadono, 1Hiroaki Iwamoto, 1Renato Naito, 1Tomoyuki Makino, 1Suguru Kadomoto, 1Ariunbold Natsagdorj, 2Evan T. Keller, 3Jian Zhang, and 1Atsushi Mizokami
    • Journal Title

      Oncotarget

      Volume: 9 Pages: 16185-16196

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04325
  • [Journal Article] Tumor necrosis factor-α induces prostate cancer cell migration in lymphatic metastasis through CCR7 upregulation.2018

    • Author(s)
      Maolake A, Izumi K, Natsagdorj A, Iwamoto H, Kadomoto S, Makino T, Naito R, Shigehara K, Kadono Y, Hiratsuka K, Wufuer G, Nastiuk KL, Mizokami A.
    • Journal Title

      Cancer science

      Volume: 109 Issue: 5 Pages: 1524-1531

    • DOI

      10.1111/cas.13586

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11128, KAKENHI-PROJECT-16K10998
  • [Journal Article] Establishment and characterization of two cabazitaxel-resistant prostate cancer cell lines.2018

    • Author(s)
      Machioka K, Izumi K, Kadono Y, Iwamoto H, Naito R, Makino T, Kadomoto S, Natsagdorj A, Keller ET, Zhang J, Mizokami A
    • Journal Title

      Oncotarget

      Volume: 9 Issue: 22 Pages: 16185-16196

    • DOI

      10.18632/oncotarget.24609

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04325, KAKENHI-PROJECT-16K10999
  • [Journal Article] Crosstalk Between Androgen-sensitive and Androgen-insensitive Prostate Cancer Cells.2018

    • Author(s)
      Takezawa Y, Izumi K, Machioka K, Iwamoto H, Naito R, Makino T, Kadomoto S, Natsagdorj A, Kadono Y, Keller ET, Zhang J, Mizokami A.
    • Journal Title

      Anticancer research

      Volume: 38 Pages: 2045-2055

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04325
  • [Journal Article] Active Estrogen Synthesis and its Function in Prostate Cancer-derived Stromal Cells2015

    • Author(s)
      K. Machioka, A. Mizokami, Y. Yamaguchi, K. Izumi, S. Hayashi and M. Namiki
    • Journal Title

      Anticancer Res

      Volume: 35 Pages: 221-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293350
  • [Journal Article] SOD3 acts as a tumor suppressor in PC-3 prostate cancer cells via hydrogen peroxide accumulation.2014

    • Author(s)
      J. Kim, A. Mizokami, M. Shin, K. Izumi, H. Konaka, Y. Kadono, Y. Kitagawa, E. T. Keller, J. Zhang and M. Namiki
    • Journal Title

      Anticancer Res

      Volume: 34 Pages: 2821-31

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26293350
  • [Journal Article] Repression of cell proliferation and androgen receptor activity in prostate cancer cells by 2'-hydroxyflavanone2013

    • Author(s)
      M. Ofude, A. Mizokami, M. Kumaki, K. Izumi, H. Konaka, Y. Kadono, Y. Kitagawa, M. Shin, J. Zhang, E. T. Keller and M. Namiki
    • Journal Title

      Anticancer Research

      Volume: 10 Pages: 4453-61

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462472
  • [Journal Article] Exogenous SPARC suppresses proliferation and migration of prostate cancer by interacting with integrin beta12013

    • Author(s)
      Shin M, Mizokami A, Kim J, Ofude M, Konaka H, Kadono Y, Kitagawa Y, Miwa S, Kumaki M, Keller ET, Namiki M
    • Journal Title

      Prostate

      Volume: 73(11) Issue: 11 Pages: 1159-1170

    • DOI

      10.1002/pros.22664

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390379, KAKENHI-PROJECT-23791747
  • [Journal Article] Repression of cell proliferation and androgen receptor activity in prostate cancer cells by 2'-hydroxyflavanone2013

    • Author(s)
      Ofude M, Mizokami A, Kumaki M, Izumi K, Konaka H, Kadono Y, Kitagawa Y, Shin M, Zhang J, Keller ET, Namiki M
    • Journal Title

      Anticancer Res

      Volume: 33(10) Pages: 4453-4461

    • URL

      http://ar.iiarjournals.org/content/33/10/4453.full.pdf+html

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390379
  • [Journal Article] Down-regulation of calcium/calmodulin-dependent protein kinase kinase 2 by androgen deprivation induces castration-resistant prostate cancer2012

    • Author(s)
      Takashi Shima, Atsushi Mizokami, Toru Miyagi, Keiichi Kawai, Kouji Izumi, Misako Kumaki, Mitsuo Ofude, Jian Zhang, Evan T. Keller, and Mikio Namiki
    • Journal Title

      The Prostate

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21592037
  • [Journal Article] Ethinylestradiol improves prostate-specific antigen levels in pretreated castration-resistant prostate cancer patients.2010

    • Author(s)
      Izumi K, Kadono Y, Shima T, Konaka H, Mizokami A, Koh E, Namiki M.
    • Journal Title

      Anticancer Res. 30

      Pages: 5201-5205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20591852
  • [Journal Article] CTEN/tensin 4 expression induces sensitivity to paclitaxel in prostate cancer.2010

    • Author(s)
      Li, Y., Mizokami, A., izumi, K., Narimoto, K., Namiki , M.(他4名)
    • Journal Title

      Prostate 70

      Pages: 48-60

    • NAID

      120001828357

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Journal Article] Preliminary results of tranilast treatment for patients with advanced castration-resistant prostate cancer.2010

    • Author(s)
      Izumi, K, Mizokami, A.Namiki, M, et al.
    • Journal Title

      Anticancer Research

      Volume: 30 Pages: 3077-3081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Journal Article] Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of T and DHT from DHEA.2009

    • Author(s)
      Mizokami, A.Kohl E.Izumi, K.Narimoto, K.Takeda, M.Honma, S.Dai, J.Keller, E.Namiki, M.
    • Journal Title

      Endocr Relat Cancer 16

      Pages: 1139-1155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Journal Article] Prostate cancer stromal cells and LNCaP cells coordinately activate the androgen receptor through synthesis of T and DHT from DHEA2009

    • Author(s)
      溝上敦, 並木幹夫, ら
    • Journal Title

      Endocrine-Related Cancer 16

      Pages: 1139-1155

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Journal Article] Tranilast inhibits hormone refractory prostate cancer cell proliferation and suppresses transforming growth factor betal-associated osteoblastic changes.2009

    • Author(s)
      Izumi, K.Mizokami, A.Li, Y.Q.Narimoto, K.Namiki, M.(他6名)
    • Journal Title

      Prostate 69

      Pages: 1222-1234

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Journal Article] Primary combined androgenbrockade in localized disease and its mechanism.2008

    • Author(s)
      Namiki M, Kitagawa Y, Mizokami A, Koh E.
    • Journal Title

      Best Pract Res Clin Endocrinol Metab. 22

      Pages: 303-315

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20659248
  • [Journal Article] Establishment and characterization of androgen-independent human prostate cancer cell lines, LN-REC4 and LNCaP-SF, from LNCaP2007

    • Author(s)
      Yoichi Iwasa, Atsushi Mizokami et al.
    • Journal Title

      International Journal of Urology 14

      Pages: 233-239

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591669
  • [Journal Article] Establishment and characterization of androgen-independent human prostate cancer cell lines. LN-REC4 and LNCaP-SF, from LNCaP2007

    • Author(s)
      Yoichi Iwasa, Atsushi Mizokami et al.
    • Journal Title

      International journal of Urology (In press)

    • Data Source
      KAKENHI-PROJECT-17591669
  • [Journal Article] Hormonal therapy2007

    • Author(s)
      Namiki, M., Ueno, S., Kitagawa, Y., Konaka, H., Mizokami, A., Koh, E., Fukagai, T
    • Journal Title

      Int J Olin Oncol 12(6)

      Pages: 427-32

    • NAID

      10020114982

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18591742
  • [Journal Article] Hormonal therapy.2007

    • Author(s)
      Namiki M, Ueno S, Kitagawa Y, Konaka H, Mizokami A, Koh E, Fukagai T.
    • Journal Title

      Int J Clin Oncol. 12

      Pages: 427-432

    • NAID

      10020114982

    • Description
      「研究成果報告書概要(和文)」より
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18591742
  • [Journal Article] The adrenal androgen androstenediol is present in prostate cancer tissue after androgen deprivation therapy and activates mutated androgen receptor2004

    • Author(s)
      Mizokami A, Namiki M, et al.
    • Journal Title

      Cancer Research 64・1

      Pages: 765-771

    • Data Source
      KAKENHI-PROJECT-15390488
  • [Journal Article] Cyclooxygenase-2 promotes prostate cancer progression2002

    • Author(s)
      Fujita, H., Koshida, K., Keller, E.T., Takahashi, Y., Yoshimito, T., Namiki, M., Mizokami, A.
    • Journal Title

      The prostate 53

      Pages: 232-240

    • Data Source
      KAKENHI-PROJECT-13671640
  • [Patent] 前立腺癌治療組成物及び前立腺癌治療2011

    • Inventor(s)
      溝上敦、並木幹夫
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2011-183183
    • Filing Date
      2011-08-25
    • Data Source
      KAKENHI-PROJECT-21592037
  • [Patent] 前立腺癌治療組成物及び前立腺癌治療組成物の有効成分のスクリーニング方法2011

    • Inventor(s)
      溝上敦, 並木幹夫
    • Industrial Property Rights Holder
      金沢大学
    • Industrial Property Number
      2011-183183
    • Filing Date
      2011-08-25
    • Data Source
      KAKENHI-PROJECT-21592037
  • [Patent] 様々な細胞でのDHEAからDHTに変換する酵素の活性測定法2008

    • Inventor(s)
      溝上敦, 並木幹夫
    • Industrial Property Rights Holder
      溝上敦, 並木幹夫
    • Filing Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Patent] 様々な細胞でのDHEAからDHTに変換する酵素の活性測定法2008

    • Inventor(s)
      溝上敦,並木幹夫
    • Industrial Property Rights Holder
      金沢大学
    • Filing Date
      2008-07-16
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] ARシグナル抑制によるCCL20-CCR6経路の活性化を介した前立腺癌転移促進機構2022

    • Author(s)
      加納洋, 泉浩二, 神島泰樹, 島田貴史, 門本卓, 岩本大旭, 八重樫洋, 溝上敦
    • Organizer
      第31回日本がん転移学会
    • Data Source
      KAKENHI-PROJECT-21K19558
  • [Presentation] KRAS活性を介した去勢抵抗性前立腺癌進展機構2022

    • Author(s)
      神島泰樹, 泉浩二, 鳥海蓮, 中川竜之介, 青山周平, 加納洋, 島田貴史, 門本卓, 内藤伶奈人, 岩本大旭, 角野佳史, 溝上敦
    • Organizer
      第81回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K09495
  • [Presentation] コーヒージテルペンkahweol acetateとcafestolのヒト腎細胞癌細胞に対する増殖・遊走抑制効果2021

    • Author(s)
      牧野友幸、泉浩二、岩本大旭、加納洋、島田貴史、門本卓、内藤伶奈人、八重樫洋、角野佳史、溝上敦
    • Organizer
      第109回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] CCL2-CCR2はアンドロゲン非依存性前立腺癌細胞のカバジタキセル体制に関与する2021

    • Author(s)
      加納洋、泉浩二、Natsagdorj Ariunbold、福田理恵、神島泰樹、島田貴史、内藤伶奈人、牧野友幸、門本卓、岩本大旭、八重樫洋、角野佳史、溝上敦
    • Organizer
      第109回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-21K19558
  • [Presentation] コーヒージテルペンkahweol acetateとcafestolのヒト腎細胞癌細胞に対する増殖・遊走抑制効果2021

    • Author(s)
      牧野友幸、泉浩二、岩本大旭、加納洋、島田貴史、門本卓、内藤伶奈人、八重樫洋、角野佳史、溝上敦
    • Organizer
      第109回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-20K09574
  • [Presentation] コーヒージテルペン酢酸カーウェオールとカフェストールのヒト腎癌細胞における抗腫瘍効果についての検討2021

    • Author(s)
      牧野友幸、泉浩二、岩本大旭、加納洋、島田貴史、門本卓、内藤伶奈人、八重樫洋、角野佳史、溝上敦
    • Organizer
      第71回日本泌尿器科学会中部総会
    • Data Source
      KAKENHI-PROJECT-20K09574
  • [Presentation] コーヒージテルペンKahweol acetateとcafestolは腎細胞癌の増殖・遊走を抑制する2021

    • Author(s)
      牧野友幸、泉浩二、岩本大旭、加納洋、島田貴史、門本卓、内藤伶奈人、八重樫洋、角野佳史、溝上敦
    • Organizer
      第30回泌尿器科分子・細胞研究会
    • Data Source
      KAKENHI-PROJECT-20K09574
  • [Presentation] 新規アンドロゲン受容体シグナル伝達阻害薬とタキサン系抗癌剤は去勢抵抗性前立腺癌の内臓転移を誘発する2021

    • Author(s)
      岩本大旭、泉浩二、内藤伶奈人、牧野友幸、門本卓、八重樫洋、角野佳史、溝上敦
    • Organizer
      第30回日本がん転移学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K19558
  • [Presentation] 新規アンドロゲン受容体シグナル伝達阻害薬とタキサン系抗癌剤は去勢抵抗性前立腺癌の内臓転移を誘発する2021

    • Author(s)
      岩本大旭、泉浩二、内藤伶奈人、牧野友幸、門本卓、八重樫洋、角野佳史、溝上敦
    • Organizer
      第30回日本がん転移学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] CCL2-CCR2はアンドロゲン非依存性前立腺癌細胞のカバジタキセル体制に関与する2021

    • Author(s)
      加納洋、泉浩二、Natsagdorj Ariunbold、福田理恵、神島泰樹、島田貴史、内藤伶奈人、牧野友幸、門本卓、岩本大旭、八重樫洋、角野佳史、溝上敦
    • Organizer
      第109回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] Anticancer effects of coffee diterpenes kahweol acetate and cafectol on prostate cancer2021

    • Author(s)
      Hiroaki Iwamoto, Kouji Izumi, Yoshifumi Kadono, Atsushi Mizokami
    • Organizer
      第79回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K19558
  • [Presentation] コーヒージテルペン酢酸カーウェオールとカフェストールのヒト腎癌細胞における抗腫瘍効果についての検討2021

    • Author(s)
      牧野友幸、泉浩二、岩本大旭、加納洋、島田貴史、門本卓、内藤伶奈人、八重樫洋、角野佳史、溝上敦
    • Organizer
      第71回日本泌尿器科学会中部総会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] コーヒージテルペンであるカーウェオールアセテートtpカフェストールは前立腺癌細胞の増殖と遊走を相乗的に阻害する2020

    • Author(s)
      岩本大旭、泉浩二、門本卓、内藤伶奈人、牧野友幸、八重樫洋、飯島将司、川口昌平、野原隆弘、重原一慶、角野佳史、溝上敦
    • Organizer
      第108回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] 新規アンドロゲン受容体シグナル伝達阻害薬とタキサン系抗癌剤は去勢抵抗性前立腺癌の内臓転移を誘発する2020

    • Author(s)
      岩本大旭、泉浩二、門本卓、八重樫洋、飯島将司、川口昌平、野原隆弘、重原一慶、角野佳史、溝上敦
    • Organizer
      第70回日本泌尿器科学会中部総会
    • Data Source
      KAKENHI-PROJECT-19K09707
  • [Presentation] コーヒージテルペンKahweol acetateとcafestolは腎細胞癌の増殖・遊走を抑制する2020

    • Author(s)
      牧野友幸、泉浩二、岩本大旭、加納洋、島田貴史、門本卓、内藤伶奈人、八重樫洋、角野佳史、溝上敦
    • Organizer
      第108回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] コーヒージテルペンであるkahweol acetateとcafestolは相乗作用で前立腺癌細胞の増殖と遊走を阻害する2019

    • Author(s)
      岩本大旭、泉浩二、ナッサグドルジアリウンボルト、門本卓、内藤伶奈人、牧野友幸、角野佳史、溝上敦
    • Organizer
      第107回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-19K09685
  • [Presentation] アンドロゲン感受性前立腺癌細胞と非感受性前立腺癌細胞のクロストーク2016

    • Author(s)
      武澤 雄太 、溝上 敦 、泉 浩二 、並木 幹夫
    • Organizer
      日本癌学会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-26293350
  • [Presentation] Crosstalk of androgen sensitive prostate cancer cells and insensitive prostate cancer cells2016

    • Author(s)
      Takezawa Yuta, Mizokami Atsushi, Machioka Kazuaki, Izumi Kouji, Iwamoto Hiroaki, Aerken Maolake, Ariunbold Natsagdorj, and Namiki Mikio
    • Organizer
      AACR Annual Meeting 2016
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2016-04-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293350
  • [Presentation] アンドロゲン感受性前立腺癌細胞と非感受性前立腺癌細胞の協調作用2015

    • Author(s)
      溝上 敦
    • Organizer
      日本癌学会
    • Place of Presentation
      名古屋国際会議場
    • Year and Date
      2015-10-08
    • Data Source
      KAKENHI-PROJECT-26293350
  • [Presentation] Down-regulation of CAMKK2 by androgen deprivation induces castration-resistant prostate cancer2012

    • Author(s)
      Takashi Shima, Atsushi Mizokami, Toru Miyagi, Keiichi Kawai, Kouji Izumi, Misako Kumaki, Zhang Jian, Evan T. Keller, and Mikio Namiki.
    • Organizer
      AACR Annual Meeting
    • Place of Presentation
      McCormick Place in Chicago(USA)
    • Year and Date
      2012-04-01
    • Data Source
      KAKENHI-PROJECT-21592037
  • [Presentation] Gene-Sの発現抑制は前立腺癌細胞の増殖を促進し、アンドロゲン高感受性を誘導する2011

    • Author(s)
      溝上敦、島崇、熊木美紗子、並木幹夫
    • Organizer
      第19回日本ステロイドホルモン学会学術集会
    • Place of Presentation
      福岡大学病院,福岡県
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-21592037
  • [Presentation] Gene-Sの発現抑制は前立腺癌細胞の増殖を促進し、アンドロゲン高感受性を誘導する2011

    • Author(s)
      溝上敦
    • Organizer
      第19回日本ステロイドホルモン学会学術集会
    • Place of Presentation
      福岡大学病院(福岡県)
    • Year and Date
      2011-11-26
    • Data Source
      KAKENHI-PROJECT-21592037
  • [Presentation] 前立腺癌の再燃に対する副腎性アンドロゲンと前立腺癌間質細胞の役割2010

    • Author(s)
      溝上敦, 熊木美紗子, 島崇, 成本一隆, 小中弘之, 角野佳史, 北川育秀, 高栄哲, 並木幹夫
    • Organizer
      第18回日本ステロイドホルモン学会
    • Place of Presentation
      愛知県産業労働センター(愛知県)
    • Year and Date
      2010-11-27
    • Data Source
      KAKENHI-PROJECT-20591852
  • [Presentation] 再燃前立腺癌に対するトラニラストによる抗腫瘍効果の臨床的検討2010

    • Author(s)
      溝上敦、泉浩二、並木幹夫
    • Organizer
      第60回日本泌尿器科学会中部総会
    • Place of Presentation
      愛知県産業労働センター(名古屋) 招待講演
    • Year and Date
      2010-12-01
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] 去勢抵抗性前立腺癌患者に対するエチニルエストラジオールの有効性2010

    • Author(s)
      角野佳史, 泉浩二, 藤田博, 北川育秀, 小中弘之, 溝上敦, 高栄哲, 並木幹夫
    • Organizer
      第26回前立腺シンポジウム
    • Place of Presentation
      東京コンファレンスセンター(東京都)
    • Year and Date
      2010-12-12
    • Data Source
      KAKENHI-PROJECT-20591852
  • [Presentation] CTEN, A Gene Related with Paclitaxel-resistance and Tumor Progression in Prostate Cancer.2009

    • Author(s)
      李友強, 溝上敦, 泉浩二, 成本一隆, 並木幹夫
    • Organizer
      Advances in Prostate Cancer Research
    • Place of Presentation
      The Westin San Diego Hotel (USA)
    • Year and Date
      2009-01-22
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] 前立腺癌間質細胞は副腎性アンドロゲンDHEAを変換し、アンドロゲン受容体を活性化する2009

    • Author(s)
      溝上敦
    • Organizer
      第18回泌尿器科分子・細胞研究会
    • Place of Presentation
      鹿児島
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] 前立腺癌間質細胞は副腎性アンドロゲンDHEAを変換し、アンドロゲン受容体を活性化する2009

    • Author(s)
      溝上敦、高栄哲、小中弘之、角野佳史、成本一隆、泉浩二、島崇、並木幹夫
    • Organizer
      第18回泌尿器分子細胞研究会
    • Place of Presentation
      鹿児島大学鶴陵会館(鹿児島県)
    • Year and Date
      2009-02-14
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] 前立腺癌の再燃に対する副腎性アンドロゲンDHEAと前立腺癌間質細胞の役割2009

    • Author(s)
      溝上敦、高栄哲、泉浩二、成本一隆、小中弘之、角野佳史、北川育秀、並木幹夫
    • Organizer
      第97回日本泌尿器科学会総会
    • Place of Presentation
      岡山コンベンションセンター(岡山県)
    • Year and Date
      2009-04-17
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] 前立腺癌の再燃に対する副腎性アンドロゲンDHEAと前立腺癌間質細胞の役割2009

    • Author(s)
      溝上敦, 並木幹夫, ら
    • Organizer
      第97回日本泌尿器科学会総会
    • Place of Presentation
      岡山コンベンションセンター (岡山県)
    • Year and Date
      2009-04-17
    • Data Source
      KAKENHI-PROJECT-20390421
  • [Presentation] 前立腺癌に対するトラニラストの抗腫瘍効果の検討2008

    • Author(s)
      泉浩二、溝上敦、李友強、成本一隆、杉本和宏、北川育秀、角野佳史、小中弘之、高栄哲、並木幹夫
    • Organizer
      第24回前立腺シンポジウム
    • Place of Presentation
      東京コンファレンスセンター(東京都)
    • Year and Date
      2008-12-14
    • Data Source
      KAKENHI-PROJECT-20390421
  • 1.  IZUMI Kouji (80646787)
    # of Collaborated Projects: 13 results
    # of Collaborated Products: 30 results
  • 2.  NAMIKI Mikio (70155985)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 19 results
  • 3.  KADONO Yoshifumi (10397218)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 6 results
  • 4.  KONAKA Hiroyuki (40334768)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 6 results
  • 5.  KYO Satoru (50272969)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 6.  KASHIDA Kiyoshi (70186667)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 7.  NARIMOTO Kazutaka (50645207)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 8.  後藤 享子 (50180245)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  HIGASHI Tatuya (90272963)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  KOH Eitetsu (90283134)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 11.  MIWA Sotarou (80507070)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 12.  MIYAGI Toru (60467107)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 13.  SHIGEHARA Kazuyoshi (20595459)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KITAGAWA Yasuhide (00452102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  KANEKO Shuichi (60185923)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NOHARA Takahiro (20733372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 17.  小川 智 (90283746)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  城戸 照彦 (20167373)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  中川 秀昭 (00097437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  八重樫 洋 (00835275)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  岡本 理恵 (50303285)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  岩本 大旭 (90847245)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 23.  IWATA Yasunori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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