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HIRAGA Kazumi  平賀 和三

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平賀 和三  ヒラガ カズミ

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Researcher Number 50252549
Other IDs
Affiliation (Current) 2025: 公益財団法人地球環境産業技術研究機構, その他部局等, 副主席研究員
Affiliation (based on the past Project Information) *help 2007: Kyoto Institute of Technology, Graduate School of Science and Technology, Assistant Professor
2006: 京都工芸繊維大学, 工芸科学研究科, 助手
2001 – 2004: 京都工芸繊維大学, 繊維学部, 助手
2003: 京都工繊大, 繊維学部, 助手
1999: 京都工芸繊維大学, 繊維学部・応用生物学科, 助手
1996 – 1999: 京都工芸繊維大学, 繊維学部, 助手
Review Section/Research Field
Principal Investigator
応用微生物学・応用生物化学 / Applied biochemistry
Except Principal Investigator
応用微生物学・応用生物化学 / Applied biochemistry / 生物・生体工学
Keywords
Principal Investigator
sedolisin / proteinase inhibitor / reaction mechanism / substrate specificity / structure and function / serine-carboxvl proteinase / elutamic nentidase / e olisin / グルタミン酸プロテアーゼ / セリン-カルボキシルプロテアーゼ … More / ペプチダーゼ / プロテアーゼ / serine-carboxy1 peptidase / プロテアーゼインヒビター / 反応メカニズム / 基質特異性 / 構造と機能 / serine-carboxyl peptidase / glutamic peptidase / eqolisin / 阻害物質 / pdr5 / 薬剤認識 / 薬剤排出ポンプ / 多剤耐性 / structure / proteinaceous / metalloproteinase / inhibitor / mutant / killer toxin / Streptomyces / metallo proteinase / Inhibitor … More
Except Principal Investigator
ペプスタチン / カルボキシルプロテアーゼ / CLN2 / fatal neurodegenerative disease / セリン-カルボキシルプロテアーゼ / 致死性遺伝病 / Structure-Function Relationship / Amino acid sequence / Catalytic residue (s) / Aspartic proteinase / Acid proteinase / Carboxyl proteinase / Pepstatin / Prokaryote / 酸性プロテアーゼ / 触媒残基 / 構造と機能 / アスパルティックプロテアーゼ / 微生物 / sedolisin / novel peptidase family / serine-carboxyl pepetidases / セドリシン / 新プロテアーゼファミリー / inhibitor / serine-carboxyl proteinase / carboxyl proteinase / three-dimensional structure / catalytic mechanism / pepstatin / Batten disease / セリンカルボシルプロテアーゼ / バッテン症 / インヒビター / セリンカルボキシルプロテアーゼ / 立体構造 / 触媒機構 / バッテン病 / Organic Solvents / Screening Procedures / Artificial Conditions / Induction / High Temperature / High Pressure / Tolerant Enzyme / 有機溶媒 / スクリーニング / 人工条件 / 誘導 / 高温 / 高圧力 / 耐性酵素 / 酵性プロテアーゼ / 分子進化 / 基質特異性 / ペプスタン / カルボキシプロテアーゼ Less
  • Research Projects

    (8 results)
  • Research Products

    (1 results)
  • Co-Researchers

    (10 People)
  •  Discovery of two novelproteinases andtheirbi rl emical resemphPrincipal Investigator

    • Principal Investigator
      HIRAGA Kazumi, 小田 耕平
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied biochemistry
    • Research Institution
      Kyoto Institute of Technology
  •  Biochemical characterization of human CLN2, related to a fatal neurodegenerative disease : On the basis of the discovery of a novel family of peptidases

    • Principal Investigator
      ODA Kohei
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Applied biochemistry
    • Research Institution
      Kyoto Institute of Technology
  •  薬剤排出ポンプによる薬剤認識・排出メカニズムの分子解析Principal Investigator

    • Principal Investigator
      平賀 和三
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Institute of Technology
  •  Microbial carboxyl proteinases related to a fatal neurodegenerative disease: proposal for a novel catalytic mechanism

    • Principal Investigator
      ODA Kohei
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO INSTITUTE OF TECHNOLOGY
  •  蛋白性メタルプロテアーゼインヒビター,SMPIの構造・機能解析と応用Principal Investigator

    • Principal Investigator
      平賀 和三
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Kyoto Institute of Technology
  •  DEVELOPMENTS OF ENZYME SYSTEMS TOLERANT TO ARTIFICIAL CONDITIONS AND ANALYSIS OF THEIR FUNCTIONS

    • Principal Investigator
      KUNUGI Shigeru
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      生物・生体工学
    • Research Institution
      KYOTO INSTITUTE OF TECHNOLOGY
  •  Structure-Function Relationships and Molecular Evolutions of Novel Carboxyl Proteinases from Microorganisms

    • Principal Investigator
      ODA Kohei
    • Project Period (FY)
      1997 – 1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Faculty of Textile Science, Kyoto Institute of Technology
  •  Structure-Function of Novel Carboxyl Proteinases from Microorganisms

    • Principal Investigator
      ODA Kohei
    • Project Period (FY)
      1996 – 1998
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      Faculty of Textile Science, Kyoto Institute of Technology

All 2007

All Journal Article

  • [Journal Article] Crystal structure of Scytalidoglutamic peptidase with its first potent inhibitor provides insights into substrate specificity and catalysis2007

    • Author(s)
      B., Fillai, M. M., Cherney, K., Hiraga, K., Takada, K., Oda, M. N., G., James
    • Journal Title

      T. Mal Biol 365

      Pages: 343-361

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18380068
  • 1.  ODA Kohei (50081584)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 1 results
  • 2.  OYAMA Hiroshi (50221700)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  KUNUGI Shigeru (70111929)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  高橋 砂織 (10142184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KAWAI Shouji
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAY John
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  DUNN Ben M
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  DUNN B.M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  KAY Jhon
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  DUNN Ben M.
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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