HORIUCHI Masahisa 堀内正久

Researcher Number	50264403
Other IDs
External Links
Affiliation (Current)	2025: 鹿児島大学, 医歯学域医学系, 教授
Affiliation (based on the past Project Information) *help	2015 – 2023: 鹿児島大学, 医歯学域医学系, 教授 2015: 鹿児島大学, 医学部, 教授 2015: 鹿児島大学, 医歯学総合研究科, 教授 2012 – 2015: 鹿児島大学, 医歯(薬)学総合研究科, 教授 2014: 鹿児島大学, 大学院医歯(薬)学総合研究科, 教授 … More 2011: 鹿児島大学, 医歯(薬)学総合研究科, 准教授 2011: 鹿児島大学, 大学院・医歯学総合研究科, 准教授 2010 – 2011: 鹿児島大学, 医歯学総合研究科, 准教授 2010: 鹿児島大学, 歯学総合研究科, 准教授 2009: 鹿児島大学, 大学院・医歯総合研究科, 准教授 2007 – 2009: 鹿児島大学, 大学院・医歯学総合研究科, 准教授 2008: 鹿児島大学, 大学院・医歯学総合研究, 准教 2003 – 2005: Kagoshima Uniyersity, Graduate School of Medical and Dental Sciences, Assistant Professor, 大学院・医歯学総合研究科, 講師 2000 – 2002: 鹿児島大学, 医学部, 講師 1996: 鹿児島大学, 医学部, 講師 1995: Kagoshima Univ.Faculty of Med.Research Associate, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Pathological medical chemistry / Public health/Health science Except Principal Investigator General internal medicine (including Psychosomatic medicine) / Hygiene / Basic Section 59020:Sports sciences-related / Pathological medical chemistry / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Basic Section 59040:Nutrition science and health science-related … More / Experimental pathology / Veterinary medical science / Sports science / Anesthesiology / Sports science / Applied health science / Applied health science / Laboratory animal science Less
Keywords	Principal Investigator カルニチン / 心肥大 / JVS mice / CDV-3 / CDV-1 / JVSマウス / 脂肪酸代謝異常 / Cardiac hypertrophy / Carnitine / Differential Display法 … More / 遺伝環境相互作用 / ビタミン要求性 / 尿中ビタミンB1排泄量 / ビタミンB1キナーゼ / ビタミンB1輸送体 / ヘキソキナーゼ / グルコース輸送体 / 脂肪肝 / 生存率 / ビタミンＢ１ / orexin / pyruvate dehydrogenase kinae / fatty aicd / cardiac hypertrophy / carnitine / PPARα / 脂肪酸毒性 / オレキシン / ピルビン酸脱水素酵素キナーゼ / 脂肪酸 / medium-chain triglyceride / Prostaglandin / cAMP responsive element / 酸素消費 / 呼吸商 / プロスタグランディンF2α / 中鎖脂肪酸 / プロスタグランディン / CREB / 食事脂質 / 食事 / POMC / AGRP / 高脂肪食 / レプチン抵抗性 / 肥満 / ヘテロ接合体 / JVS(juvenile visceral steatosis)mouse. / RACE法 / リボソーマル蛋白 / ANP / JVS(Juvenile Visceral Steatosis)マウス … More Except Principal Investigator カルニチン / JVSマウス / 脂肪酸代謝 / 中枢神経系 / 絶食 / 遺伝子発現 / 動物モデル / 食事療法 / マイクロミニピッグ / オレキシン / 脂肪酸酸化 / Octn2 / PDK4 / Cardiac hypertrophy / AP-1 / 心肥大 / 糖尿病網膜症 / レプチン受容体 / インスリン分泌不全 / 食事たんぱく質 / 糖尿病腎症 / 糖尿病 / 栄養指導 / ストレス脆弱性 / 脂肪酸代謝異常 / 不妊 / 尿たんぱく / たんぱく質 / CKD / 随時尿 / 異化 / 脂質 / ヨウ素 / 食事摂取頻度調査 / 体細胞クローン / 遺伝子改変動物 / 疾患モデル動物 / クローン / 受精卵遺伝子改変 / 受精卵採取 / 体細胞核移植 / クローンブタ / アルツハイマー病 / クローン動物 / 遺伝子改変 / マイクロミニブタ / 栄養学 / 循環器・高血圧 / 病理学 / ミニブタモデル / 梗塞病変 / ホモシステイン / メトトレキサート / 高ホモシステイン血症 / 葉酸 / 脳梗塞 / 心筋梗塞 / ミニブタ / 動脈硬化 / アミノ酸代謝 / 糖代謝 / ミトコンドリア / 遊離脂肪酸 / L-カルニチン / プロポフォール / アミノ酸 / Long-chain fatty acid / Juvenile visceral steatosis (JVS) mice / CDV (carnitine deficiency-associated genes) / Carnitine deficiency / カルニチン膜輸送体 / カルニチン欠乏 / CDV-3 / CDV-1 / カルチニン欠乏 / Differential display / JVS (Juvenile Visceral Steatosis) mouse / Long-chain unsaturated fatty acid / Urea cycle / Hyperammonemia / Carnitine / 膜輸送活性 / Atrial natriuretic factor / グルココルチコイド / jvs(juvenile visceral steatosis)マウス / JVS(Juvenile Visceral Steatosis)マウス / c-jun / JUS(juvenile Visceral Steatosi s)マウス / 長鎖不飽和脂肪酸 / differential display / 尿素サイクル / 高アンモニア血症 / 糖尿病性網膜症 / 漢方 / デスアシルグレリン / アシルグレリン / サルコペニア / 炎症 / 老化 / 癌性悪液質 / 終末期 / 活性酸素種 / エピジェネティック / 発がん / 次亜塩素酸 / ミエロペルオキシダーゼ / ハロゲン化ストレス / ハロゲン化DNA / HL60 / 白血病 / ベンゼントリオール / ベンゼン / 肥満 / 機能性胃腸症 / 摂食障害 / 食欲 / アディポサイトカイン / ラット / マウス / マノメトリック法 / 消化管運動 / 心身相関 / 心療内科学 / (Pseudomonas aeruginosa) / 変異原 / 緑膿菌 / Pseudomonas aeruginosa(緑膿菌) / rpoB / rifampicin / gyrA / ciprofloxacin / 薬剤耐性菌 / 変異原物質 / 神経科学 / 臨床 / トランスレーショナルリサーチ / 神経医学 / 医療・福祉 / 遺伝子 / 代謝 / 活性酸素 / 運動 / 構造タンパク / サーファクタント / 酸化ストレス / 自然免疫 / 肺炎 / 肺 / 自発運動 / 習慣的運動 / ANP / 組織学 / 心筋症 Less

カルニチン投与が全身代謝と中枢神経系におよぼす効果：カルニチン欠損マウスを用いて
- Principal Investigator
  
  吉田剛一郎
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Institute of Fitness and Sports in Kanoya
Female infertility in carnitine-deficient mice: focus on the relationship between fatty acid toxicity and social stress vulnerability.
- Principal Investigator
  
  Ushikai Miharu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kagoshima University
Molecular mechanisms of prolonged effect of carnitine administration on whole-body metabolism and the central nervous system
- Principal Investigator
  
  Yoshida Goichiro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59020:Sports sciences-related
- Research Institution
  National Institute of Fitness and Sports in Kanoya
Roles of vitamin B1 in fatty acid metabolism abnormalitiesPrincipal Investigator
- Principal Investigator
  
  Horiuchi Masahisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kagoshima University
Examination of nutritional factors related to diabetic nephropathy and/or retinopathy in patients enrolled from Kagoshima city CKD prevention network
- Principal Investigator
  
  Arimura Emi
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kagoshima Prefectural College
Development of infarction model induced by folic acid deficiency using a Microminipig atherosclerosis model
- Principal Investigator
  
  Kawaguchi Hiroaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Veterinary medical science
- Research Institution
  Kagoshima University
Production of gene-modified pig of next-generation model for Alzheimer's disase
- Principal Investigator
  
  Tanimoto Akihide
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kagoshima University
What is the cause of carnitine administration? Prolonged effects on general metabolism and central nervous system
- Principal Investigator
  
  YOSHIDA Goichiro
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sports science
- Research Institution
  National Institute of Fitness and Sports in Kanoya
The mechanism of propofol infusion syndrome and the prevention effects by canrnitine
- Principal Investigator
  
  Moriyama Takahiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Kagoshima University
Development of a novel nutritional treatment for diabetic retinopathy based on scientific evidence.
- Principal Investigator
  
  ARIMURA EMI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kagoshima Prefectural College
Improvement of quality of life in terminal stages -approaches from acyl ghrelin signaling -
- Principal Investigator
  
  ASAKAWA Akihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kagoshima University
Prolonged effect of carnitine administration on metabolism and central nervous system of fasted carnitine-deficient mice
- Principal Investigator
  
  YOSHIDA GOICHIRO
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Sports science
- Research Institution
  National Institute of Fitness and Sports in Kanoya
To elucidate effects of a low-protein diet under molecular levels, aiming at constructing the nutrition education.
- Principal Investigator
  
  ARIMURA Emi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Kagoshima Prefectural College
環境介入による薬剤耐性菌の発生制御を目指す研究
- Principal Investigator
  
  竹内亨
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kagoshima University
Effects of fat in diets on heterozygous mutants of carnitine-deficient micePrincipal Investigator
- Principal Investigator
  
  HORIUCHI Masahisa
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Public health/Health science
- Research Institution
  Kagoshima University
Maintaining an ideal body weight and stress response
- Principal Investigator
  
  ASAKAWA Akihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kagoshima University
ベンゼン発がんのエピジェネティック解析
- Principal Investigator
  
  竹内亨
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  Kagoshima University
Translational research on intractable neuro-metabolic disorders
- Principal Investigator
  
  INUI Akio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine (including Psychosomatic medicine)
- Research Institution
  Kagoshima University
Studies on the prevention of pneumonia by habitual voluntary exercise
- Principal Investigator
  
  TAKEUCHI Toru
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Hygiene
- Research Institution
  Kagoshima University
Molecular mechanism of cardiac hypertrophy caused by lipid toxicityPrincipal Investigator
- Principal Investigator
  
  HORIUCHI Masahisa
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Identification of nuclear proteins involved in cardiac hypertrophy caused by abnormality of fatty acid metabolismPrincipal Investigator
- Principal Investigator
  
  HORIUCHI Masahisa
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Structure and function of novel genes which differentially expressed in cardiac hypertrophy of carnitine deficiency
- Principal Investigator
  
  SAHEKI Takeyori
- Project Period (FY)
  1998 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
カルニチン欠乏による心肥大形成機序の解明-カルニチン投与に応答する遺伝子の単離と解析-Principal Investigator
- Principal Investigator
  
  堀内正久
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
心筋症を伴うカルニチン欠乏マウスのNa利尿ペプチドの動態と心筋病変の解明
- Principal Investigator
  
  鈴木秀作
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kagoshima University
カルニチン欠乏による心肥大形成機序の解明-カルニチン投与に応答する遺伝子の単離を目指して-Principal Investigator
- Principal Investigator
  
  堀内正久
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University
Pathogenesis and pathophysiology of inherited carnitine deficiency using carnitine-deficient JVS mice
- Principal Investigator
  
  SAHEKI Takeyori
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Kagoshima University

[Book] ビタミン・バイオファクター総合辞典2021
- Author(s)
  日本ビタミン学会編（堀内正久）
- Total Pages
  672
- Publisher
  朝倉書店
- ISBN
  9784254102925
- Data Source
  KAKENHI-PROJECT-18K10053
[Book] モデル動物の作製と維持(編集:森脇和郎, 山村研一, 米川博通)2004
- Author(s)
  佐伯武頼, 小林圭子, 堀内正久(分担)
- Total Pages
  956
- Publisher
  エル・アイ・シー(Life-Science Information Center)(東京)
- Data Source
  KAKENHI-PROJECT-16590250
[Book] モデル動物の作製と維持(編集 : 森脇和郎、山村研一、米川博通)2004
- Author(s)
  佐伯武頼, 小林圭子, 堀内正久(分担)
- Total Pages
  956
- Publisher
  エル・アイ・シー(Life-Science Information Center)東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] Acute repeated cage exchange stress modifies urinary stress and plasma metabolic profiles in male mice2023
- Author(s)
  Sayuri Fushuku, Miharu Ushikai, Emi Arimura, Yuga Komaki, Masahisa Horiuchi
- Journal Title
  
  PLoS One
  
  Volume: 18 Issue: 10 Pages: e0292649-e0292649
- DOI
  10.1371/journal.pone.0292649
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11038
[Journal Article] Comparison of Dipstick and Quantitative Tests for Proteinuria and Haematuria in Middle-aged, Japanese Male Workers: A single-center study2021
- Author(s)
  Kanako Ikeda, Masaharu Abe, Izumi Masamoto, Chikako Ishii, Emi Arimura, Miharu Ushikai, Kaoru Oketani, Teruto Hashiguchi, Masahisa Horiuchi
- Journal Title
  
  Health Science Reports
  
  Volume: - Issue: 2
- DOI
  10.1002/hsr2.267
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11038, KAKENHI-PROJECT-20K10430
[Journal Article] Higher Branched-chain Amino Acids and Lower Serine Exist in the Plasma of Nondiabetic Mice: A Comparison Between High- and Low-protein Diet Conditions2021
- Author(s)
  Emi Arimura, Miharu Ushikai, Masahisa Horiuchi
- Journal Title
  
  in vivo
  
  Volume: 35(3) Issue: 3 Pages: 1555-1560
- DOI
  10.21873/invivo.12410
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11038, KAKENHI-PROJECT-20K10430
[Journal Article] Salt intake questionnaire and salt taste sensitivity test for the volunteers participating in a CKD enlightenment event in Kagoshima city2019
- Author(s)
  有村恵美、大山律子、町田美由紀、日高宏実、阿部正治、中熊美和、堀内正久
- Journal Title
  
  Journal of the Japan Dietetic Association
  
  Volume: 62 Issue: 2 Pages: 89-95
- DOI
  10.11379/jjda.62.89
- NAID
  130007584911
- ISSN
  0013-6492, 2185-6877
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11038
[Journal Article] Effects of Dietary and Lighting Conditions on Diurnal Locomotor Activity and Body Temperature in Microminipigs.2018
- Author(s)
  Takeishi K, Kawaguchi H, Akioka K, Noguchi M, Arimura E, Abe M, Ushikai M, Okita S, Tanimoto A, Horiuchi M.
- Journal Title
  
  In Vivo
  
  Volume: 32 Issue: 1 Pages: 55-62
- DOI
  10.21873/invivo.11204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05176
[Journal Article] Potential predictors of susceptibility to occupational stress in Japanese novice nurses - a pilot study.2017
- Author(s)
  Okita S, Daitoku S, Abe M, Arimura E, Setoyama H, Koriyama C, Ushikai M, Kawaguchi H, Horiuchi M.
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 22 Issue: 1 Pages: 20-20
- DOI
  10.1186/s12199-017-0641-8
- NAID
  210000130209
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08023
[Journal Article] Carnitine deficiency induces a short QT syndrome2016
- Author(s)
  Roussel J, Labarthe F, Thireau J, Ferro F, Farah C, Roy J, Horiuchi M, Tardieu M, Lefort B, Francois Benoist J, Lacampagne A, Richard S, Fauconnier J, Babuty D, Le Guennec JY.
- Journal Title
  
  Heart Rhythm
  
  Volume: 13 Issue: 1 Pages: 165-174
- DOI
  10.1016/j.hrthm.2015.07.027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01623, KAKENHI-PROJECT-23500783
[Journal Article] Birth of Cloned Microminipigs Derived from Somatic Cell Nuclear Transfer Embryos that have been Transiently Treated with Valproic Acid.2016
- Author(s)
  Miyoshi K, Kawaguchi H, Maeda K, Sato M, Akioka K, Noguchi M, Horiuchi M, Tanimoto A.
- Journal Title
  
  Cellular Reprogramming
  
  Volume: 18 Pages: 390-400
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08023
[Journal Article] Deteriorated glucose metabolism with a high-protein,low-carbohydrate diet in db mice, an animal model of a type 2 diabetes, might be caused by insufficient insulin secretion2016
- Author(s)
  Emi Arimura,Wijang Pralampita Pulong, Ancha Caesarina Novi Marchianti, Miwa Nakakuma, Masaharu Abe, Miharu Ushikai, Masahisa Horiuchi
- Journal Title
  
  Eurropean Journal of Nutrition
  
  Volume: in press Issue: 1 Pages: 237-246
- DOI
  10.1007/s00394-015-1075-y
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25350873
[Journal Article] Birth of Cloned Microminipigs Derived from Somatic Cell Nuclear Transfer Embryos that have been Transiently Treated with Valproic Acid.2016
- Author(s)
  Miyoshi K, Maeda K, Akioka K, Sato M, Kawaguchi H, Tanimoto A
- Journal Title
  
  Cellular Reprogramming
  
  Volume: 6 Issue: 6 Pages: 390-400
- DOI
  10.1089/cell.2016.0025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-16K08085, KAKENHI-PROJECT-16H05176
[Journal Article] 犬の輸送ストレス軽減のための新規鍼治療の試み.2016
- Author(s)
  川口博明, 笹竹　洋, 野口倫子, 秋岡幸兵, 三浦直樹, 武石嘉一朗, 堀内正久, 谷本昭英.
- Journal Title
  
  日本獣医師会雑誌
  
  Volume: 69 Pages: 143146-143146
- NAID
  130005147266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08023
[Journal Article] 実験研究による解析、食と生活関連疾患（心疾患・脂肪肝・疲労病態）2015
- Author(s)
  堀内正久,中熊美和, 有村恵美，牛飼美晴，吉田剛一郎
- Journal Title
  
  日本衛生学会誌
  
  Volume: 70 Pages: 110-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25350873
[Journal Article] 実験研究による解析，食と生活習慣関連疾患（心疾患・脂肪肝・疲労病態）2015
- Author(s)
  堀内正久，中熊美和，有村恵美，牛飼美晴，吉田剛一郎
- Journal Title
  
  日本衛生学雑誌
  
  Volume: 70
- NAID
  130005070851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500783
[Journal Article] Voluntary exercise under a food restriction condition decreases blood branched-chain amino acid levels, in addition to improvement of glucose and lipid metabolism, in db mice, animal model of type 2 diabetes2014
- Author(s)
  Marchianti AC, Arimura E, Ushikai M, Horiuchi M
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 19 Issue: 5 Pages: 339-347
- DOI
  10.1007/s12199-014-0400-z
- NAID
  50009312840
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23500783, KAKENHI-PROJECT-24590892, KAKENHI-PROJECT-25350873
[Journal Article] Low-protein diet improves blood and urinary glucose levels and renal manifestations of diabetes in C57BLKS-db/db mice2013
- Author(s)
  Emi Arimura、Masahisa Horiuchi、Hiroaki Kawaguchi、Noriaki Miyoshi、Kohji Aoyama、Toru Takeuchi
- Journal Title
  
  European Journal of Nutrition
  
  Volume: Vol.52(2) Issue: 2 Pages: 813-824
- DOI
  10.1007/s00394-012-0387-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500650
[Journal Article] Acupucture improves sleep conditions of minipigs representing diurnalanimals through an anatomically similar point to the acupoint(GV20)effective for humans2012
- Author(s)
  Ka-ihiro Takeishi、Masahisa Horiuchi、 Hiroaki Kawaguchi、Yoshiki Deguchi、 Hiroyuki Izumi、Emi Arimura、SatoshiKuchiwa、Akihide Tanimoto、Toru Takeuchi
- Journal Title
  
  Evidence-Based Complementaryand Alternative Medicine
  
  Volume: 2012 Pages: 472982-472982
- DOI
  10.1155/2012/472982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500650
[Journal Article] Acupuncture improves sleep conditions of minipigs representing diurnal animals through an anatomically similar point to the acupoint(GV20) effective for humans2012
- Author(s)
  Takeishi K-I, Horiuchi M, Kawaguchi H, Deguchi Y, Izumi H, Arimura E, Kuchiiwa S, Tanimoto A, Takeuchi T
- Journal Title
  
  Evid Based Complement Alternat Med
  
  Volume: 2012 Pages: 472982-472982
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Long-term voluntary exercise, representing habitual exercise, lowers viseeral fat and alters plasma amino acid levels in mice2012
- Author(s)
  Takeshita H, Horiuchi M, et al
- Journal Title
  
  Environ Health Prev Med
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Low-protein diet improves blood and urinary glucose levels and renal manifestations of diabetes in C57BLKS-db/db mice2012
- Author(s)
  Arimura E, Horiuchi M, Kawaguchi H, Miyoshi N, Aoyama K, Takeuchi T
- Journal Title
  
  Eur J Nutr
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Benzene metabolite, 1, 2, 4-benzenetriol, induced halogenated DNA and tyrosine representing halogenative stress in human myeloid cell line HL-602012
- Author(s)
  Nishikawa T, Miyahara E, Horiuchi M, Izumo K, Okamoto Y, Kawai Y, Kawano Y, Takeuchi T.
- Journal Title
  
  Environ Health Perspect
  
  Volume: 120 Pages: 62-67
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Environmental mutagens may be implicated in the emergence of drug-resistant microorganisms2011
- Author(s)
  Miyahara E, Nishie M, Takumi S, Miyanohara H, Nishi J, Yoshiie K, Oda H, Takeuchi M, Komatsu M, Aoyama K, Horiuchi M, Takeuchi T
- Journal Title
  
  FEMS Microbiol Lett
  
  Volume: 317 Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Long-term voluntary exercise, representing habitual exercise, lowers visceral fat and alters plasma amino acid levels in mice2011
- Author(s)
  Takeshita H, Horiuchi M, Izumo K, Kawaguchi H, Arimura E, Aoyama K, Takeuchi T
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 4
- NAID
  10030945703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate2011
- Author(s)
  Kato T, Kawaguchi H, Miyoshi N, Aoyama K, Komatsu M, Horiuchi M, Yoshida H, Takeuchi T
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: (in press)
- NAID
  10029520529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659158
[Journal Article] Long-term voluntary exercise, representing habitual exercise, lowers visceral fat and alters plasma amino acid levels in mice2011
- Author(s)
  Haruko Takeshita、Masahisa Horiuchi、Kimiko Izumo、Hiroaki Kawaguchi、Emi Arimura、 Kohji Aoyama、Toru Takeuchi
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: Vol.17(4) Issue: 4 Pages: 275-284
- DOI
  10.1007/s12199-011-0249-3
- NAID
  10030945703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500650
[Journal Article] Benzene induces cytotoxicity without metabolic activation2011
- Author(s)
  Nishikawa T, Izumo K, Miyahara E, Horiuchi M, Okamoto Y, Kawano K, Takeuchi T
- Journal Title
  
  Journal of Occupational Health
  
  Volume: 53 Pages: 84-92
- NAID
  10027959345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390191
[Journal Article] Environmental mutagens may be implicated in the emergence of drug-resistant microorganisms.2011
- Author(s)
  MiyaharaE, Nishie M, Takumi S, Miyanohara H, Nishi J, Yoshiie K, Oda H, Takeuchi M, Komatsu M, Aoyama K, Horiuchi M, Takeuchi T
- Journal Title
  
  FEMS Microbiology Letters
  
  Volume: 317 Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390191
[Journal Article] Benzene induces cytotoxicity without metabolic activation2011
- Author(s)
  Nishikawa T, Izumo K, Miyahara E, Horiuchi M, Okamoto Y, Kawano K, Takeuchi T
- Journal Title
  
  Journal of Occupational Health
  
  Volume: 53 Pages: 84-92
- NAID
  10027959345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659158
[Journal Article] Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate2011
- Author(s)
  Kato T, Kawaguchi H, Miyoshi N, Aoyama K, Komatsu M, Horiuchi M, Yoshida H, Takeuchi T.
- Journal Title
  
  Environ Health Prev Med
  
  Volume: 16 Pages: 232-238
- NAID
  10029520529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate2011
- Author(s)
  Kato T, Kawaguchi H, Miyoshi N, Aoyama K, Komatsu M, Horiuchi M, Yoshida H, Takeuchi T
- Journal Title
  
  Environmental Health and Preventive Medicine
  
  Volume: (in press)
- NAID
  10029520529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390191
[Journal Article] Effect of exercise and high-fat diet on plasma adiponectin and nesfatin levels in mice2011
- Author(s)
  Chaolu H, Asakawa A, Ushikai M, Li YX, Cheng KC, Li JB, Zoshiki T, Terashi M, Tanaka C, Atsuchi K, Sakoguchi T, Tsai M, Amitani H, Horiuchi M, Takeuchi T, Inui A.
- Journal Title
  
  Exp Therap Med
  
  Volume: 2 Pages: 369-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590768
[Journal Article] Benzene induces cytotoxicity without metabolic activation2011
- Author(s)
  Nishikawa T, Izumo K, Miyahara E, Horiuchi M, Okamoto Y, Kawano Y, Takeuchi T.
- Journal Title
  
  J Occup Health
  
  Volume: 53 Pages: 84-92
- NAID
  10027959345
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart2011
- Author(s)
  Ushikai M, Horiuchi M, Kobayashi K, Matuda S, Inui A, Takeuchi T, Saheki T
- Journal Title
  
  Mol Genet Metab
  
  Volume: 102 Pages: 349-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Effect of exercise and high-fat diet on plasma adiponectin and nesfatin levels in mice2011
- Author(s)
  Chaolu H, Asakawa H, Ushikai M, Li YX, Cheng KC, Li JB, Zoshiki T, Terashi M, Tanaka C, Atsuchi K, Sakoguchi T, Tsai M, Amitani H, Horiuchi M, Takeuchi T, Inui A
- Journal Title
  
  Exp Ther Med
  
  Volume: 2 Pages: 369-373
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart2010
- Author(s)
  Ushikai M, Horiuchi M, et al
- Journal Title
  
  Mol Genet Metab
  
  Volume: 102 Pages: 349-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart.2010
- Author(s)
  Ushikai M, Horiuchi M, Kobayashi K, Matuda S, Inui A, Takeuchi T, Saheki T.
- Journal Title
  
  Mol Genet Metab.
  
  Volume: 102(3) Pages: 349-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390199
[Journal Article] Novel microminipig model of atherosclerosis by high fat and high cholesterol diet,established in Japan2010
- Author(s)
  Miyoshi N, Horiuchi M, Inokuchi Y, Miyamoto Y, Miura N, Tokunaga S, Fujiki M, Izumi Y, Miyajima H, Nagata R, Misumi K, Takeuchi T, Tanimoto A, Yasuda N, Yoshida H, Kawaguchi H.
- Journal Title
  
  in vivo
  
  Volume: 24 Pages: 671-680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Novel microminipig model of atherosclerosis by high fat and high cholesterol diet, established in Japan2010
- Author(s)
  Miyoshi N, Horiuchi M, et al
- Journal Title
  
  In Vivo
  
  Volume: 24 Pages: 671-680
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart.2010
- Author(s)
  Ushikai M, Horiuchi M, Kobayashi K, Matuda S, Inui A, Takeuchi T, Saheki T.
- Journal Title
  
  Mol Genet Metab. 102(3)
  
  Pages: 349-355
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390199
[Journal Article] Failure of the feeding response to fasting in carnitie-deficient juvenile visecal steatosis (JVS) mice : involvement of defective acly-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus.2009
- Author(s)
  Sakoguchi T, Horiuchi M, Asakawa A, Ushikai M, Yoshida G, Fujimiya M, Kato I, Nakazato M, Takeuchi T, Saheki T, Inui A.
- Journal Title
  
  Biochim Biophys Acta. 1792(11)
  
  Pages: 1087-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390199
[Journal Article] Dehydroepiandrosterone increased oxidative stress in a human cell line during differentiation2009
- Author(s)
  Izumo K, Horiuchi M, Komatsu M, Aoyama K, Bandow K, Matsuguchi T, Takeuchi M, Takeuchi T.
- Journal Title
  
  Free Radic Res 43
  
  Pages: 922-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Early neonatal onset carbamoyl-phosphate synthase 1 deficiency treated with continuous hemodiafiltration and early living-related liver transplantation2009
- Author(s)
  Ishida T, Hiroma T, Hashikura Y, Horiuchi M, Kobayashi K, Nakamura T.
- Journal Title
  
  Pediatr Int
  
  Volume: 51 Pages: 409-410
- NAID
  10025347102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Early neonatal onset carbamoyl-phosphate synthase 1 deficiency treated with continuous hemodiafiltration and early living-related liver transplantation2009
- Author(s)
  Ishida T, Hiroma T, Hashikura Y, Horiuchi M, Kobayashi K, Nakamura T.
- Journal Title
  
  Pediatr Int 51
  
  Pages: 409-410
- NAID
  10025347102
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis(JVS)mice : involvement of defective acyl-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus2009
- Author(s)
  Sakoguchi T, Horiuchi M, Asakawa A, Ushikai M, Yoshida G, Fujimiya M, Kato I, Nakazato M, Takeuchi T, Saheki T, Inui A.
- Journal Title
  
  Biochim Biophys Acta-Mol basis of Dis 1792
  
  Pages: 1087-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Dehyderoepiandrosterone increased oxidative stress in a human cell line during differentiation2009
- Author(s)
  Izumo K, Horiuchi M, Komatsu M, Aoyama K, Bandow K, Matsuguchi T, Takeuchi M, Takeuchi T.
- Journal Title
  
  Free Radic Res
  
  Volume: 43 Pages: 922-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis(JVS)mice : Involvement of defective acyl-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypoth alamus2009
- Author(s)
  Sakoguchi T, Horiuchi M, Asakawa A, Ushikai M, Yoshida G, Fujimiya M, Kato I, Nakazato M, Takeuchi T, Saheki T, Inui A.
- Journal Title
  
  Biochimica et Biophysica Acta-Molecular Basis of Disease 1792
  
  Pages: 1087-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390191
[Journal Article] Dehydroepiandrosterone increased oxidative stress in a human cell line during differentiation2009
- Author(s)
  Izumo K, Horiuchi M, Komatsu M, Aoyama K, Bandow K, Matsuguchi T, Takeuchi M, Takeuchi T.
- Journal Title
  
  Free Radical Research 43
  
  Pages: 922-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390191
[Journal Article] Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis(JVS)mice : Involvement of defective acyl-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus2009
- Author(s)
  Sakoguchi T, Horiuchi M, Asakawa A, Ushikai M, Yoshida G, Fujimiya M, Kato I, Nakazato M, Takeuchi T, Saheki T, Inui A.
- Journal Title
  
  Biochimica et Biophysica Acta-Molecular Basis of Disease 1792
  
  Pages: 1087-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659158
[Journal Article] Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis(JVS)mice : involvement of defective acylghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus2009
- Author(s)
  Sakoguchi T, Horiuchi M, Asakawa A, Ushikai M, Yoshida G, Fujimiya M, Kato I, Nakazato M, Takeuchi T, Saheki T, Inui A
- Journal Title
  
  Biochim Biophys Acta 1792(11)
  
  Pages: 1087-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390199
[Journal Article] Failure of the feeding response to fasting in carnitine-deficient juvenile visceral steatosis(JVS) mice : involvement of defective acyl-ghrelin secretion and enhanced corticotropin-releasing factor signaling in the hypothalamus2009
- Author(s)
  Sakoguchi T, Horiuchi M, Asakawa A, Ushikai M, Yoshida G, Fujimiya M, Kato I, Nakazato M, Takeuchi T, Saheki T, Inui A.
- Journal Title
  
  Biochim Biophys Acta(Molecular Basis of Disease)
  
  Volume: 1792 Pages: 1087-1093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590704
[Journal Article] Dehydroepiandrosterone increased oxidative stress in a human cell line during differentiation2009
- Author(s)
  Izumo K, Horiuchi M, Komatsu M, Aoyama K, Bandow K, Matsuguchi T, Takeuchi M, Takeuchi T.
- Journal Title
  
  Free Radical Research 43
  
  Pages: 922-931
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659158
[Journal Article] Involvement of reactive oxygen species in MCLR-induced cytogenotoxicity2007
- Author(s)
  Nong QQ, Komatsu M, Izumo K, Indo PH, Xu BH, Aoyama K, Majima HJ, Horiuchi M, Morimoto K, Takeuchi T.
- Journal Title
  
  Free Radical Eesearch 41
  
  Pages: 1326-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390183
[Journal Article] Involvement of reactive oxygen species in Microcystin-LR-induced cytogenotoxicity2007
- Author(s)
  Nong Q, Komatsu M, Izumo K, Indo HP, Xu B, Aoyama K, Majima HJ, Horiuchi M, Morimoto K, Takeuchi T
- Journal Title
  
  Free Radic Res. 41(12)
  
  Pages: 1326-37
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390183
[Journal Article] Fasting-induced reduction in locomotor activity and reduced response of prexin neurons in carnitine-deficient mice.2006
- Author(s)
  Goichiro Yoshida, Meng Xian Li, Masahisa Horiuchi, et al.
- Journal Title
  
  Neurosci Res 55
  
  Pages: 78-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] Attenuation of cardiac hypertrophy in carnitine-deficient juvenile visceral steatosis(JVS) mice achieved by lowering dietary lipid.2006
- Author(s)
  Md Abdul Jalil, Masahisa Horiuchi, et al.
- Journal Title
  
  J Biochem 139・2
  
  Pages: 263-270
- NAID
  10018847819
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] Attenuation of cardiac hypertrophy in carnitine-deficient juvenile visceral steatosis (JVS) mice achieved by lowering dietary lipid.2006
- Author(s)
  Md.Abdul Jalil, Masahisa Horiuchi, et al.
- Journal Title
  
  J Biochem. 139
  
  Pages: 263-270
- NAID
  10018847819
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] Fasting-induced reduction in locomotor activity and reduced response of orexin neurons in carnitine-deficient mice.2006
- Author(s)
  Goichiro Yoshida, Meng Xian Li, Masahisa Horiuchi, et al.
- Journal Title
  
  Neurosci Res 55・1
  
  Pages: 78-86
- NAID
  10020616692
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] カルニチン欠乏・脂質代謝と疲労2004
- Author(s)
  堀内正久, 他
- Journal Title
  
  Molecular Medicine 41
  
  Pages: 1235-1242
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] カルニチン欠乏・脂質代謝と疲労2004
- Author(s)
  堀内正久, 他
- Journal Title
  
  Molecular Medicine 41・10
  
  Pages: 1235-1242
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590250
[Journal Article] Low-protein diet improves blood and urinary glucose levels and renal manifestations of diabetes in C57BLKS-db/db mice
- Author(s)
  Emi Arimura, Masahisa Horiuchi, Hiroaki Kawaguchi, Noriaki Miyoshi Kohji Aoyama, Toru Takeuchi
- Journal Title
  
  European Journal of Nutrition
- Description
  in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] 脂肪酸代謝異常症におけるストレス脆弱性の解析2022
- Author(s)
  牛飼美晴, 小牧祐雅, 堀内正久
- Organizer
  第92回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K10430
[Presentation] 一事業所の、勤労世代における喫煙者に関する現状2022
- Author(s)
  小牧祐雅, 牛飼美晴, 堀内正久
- Organizer
  第95回日本産業衛生学会
- Data Source
  KAKENHI-PROJECT-20K10430
[Presentation] 頻回の新規環境負荷に対するマウスの応答性について2022
- Author(s)
  冨宿小百合, 牛飼美晴, 小牧祐雅, 堀内正久
- Organizer
  第92回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K10430
[Presentation] 栄養学・ビタミン学研究における連携2021
- Author(s)
  堀内正久
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K10053
[Presentation] 脂肪酸代謝障害におけるストレス脆弱性の解析2021
- Author(s)
  牛飼美晴、小牧祐雅、吉田剛一郎、堀内正久
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K11492
[Presentation] 脂肪酸代謝障害におけるストレス脆弱性の解析2021
- Author(s)
  牛飼美晴, 小牧祐雅, 吉田剛一郎, 堀内正久
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20K10430
[Presentation] たんぱく質摂取量の血中アミノ酸への影響 : 野生型と2型糖尿病モデルマウスでの比較2021
- Author(s)
  堀内正久, 有村恵美, 牛飼美晴
- Organizer
  第91回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-20K10430
[Presentation] 脂肪酸代謝異常時の心臓糖取り込み促進について：カルニチン欠乏マウスの新規病態解析2019
- Author(s)
  牛飼美晴、松元菜奈、堀内正久
- Organizer
  第89回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-18K10053
[Presentation] 行性動物マイクロミニピッグにおける無麻酔下経時的脳脊髄液採取法の確立.2018
- Author(s)
  川口博明, 阿部正治, 牛飼美晴, 大井紗弓, 柚川藍色, 吉川哲也, 和泉博之, 谷本昭英, 堀内正久.
- Organizer
  第34回日本毒性病理学会総会及び学術集会
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] 高たんぱく低炭水化物食と低たんぱく高炭水化物食が腎機能・窒素代謝に及ぼす影響.2017
- Author(s)
  有村恵美, 中熊美和, 　阿部正治, 牛飼美晴, 川口博明, 堀内正久.
- Organizer
  第２０回日本病態栄養学会年次学術集会
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2017-01-13
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] 削蹄のいらないミニブタ用床材の開発.2017
- Author(s)
  川口博明, 秋岡幸兵, 阿部正治, 牛飼美晴, 松尾　恵, 堀内正久, 谷本昭英.
- Organizer
  第35回九州実験動物研究会総会／第37回日本実験動物技術者協会研究発表会.
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] レプチン受容体欠損マウスを用いた時期特異的レプチンシグナル動態の解析.2017
- Author(s)
  牛飼美晴, Pulong Wijang Pralampita, 阿部正治, 川口博明, 有村恵美, 中熊美和, 堀内正久.
- Organizer
  第87回日本衛生学会学術総会
- Place of Presentation
  宮崎県シーガイヤ・コンベンションセンター（宮崎県宮崎市）
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] ミニブタを用いた食事・光による生体リズムへの影響解析.2017
- Author(s)
  川口博明, 武石嘉一朗, 阿部正治, 有村恵美, 牛飼美晴, 堀内正久.
- Organizer
  第87回日本衛生学会学術総会
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] 食事蛋白質量が2型糖尿病網膜症に及ぼす影響～レプチン受容体欠損マウスを用いた検討～2016
- Author(s)
  有村恵美, 岡谷秀明, 荒木智陽, 川口博明, 中熊美和, 阿部正治, 牛飼美晴, 和泉博之, 堀内正久.
- Organizer
  第54回日本糖尿病学会九州地方会
- Place of Presentation
  かごしま県民交流センター（鹿児島県鹿児島市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] マイクロミニピッグにおける高塩分食摂取の生体応答.2016
- Author(s)
  武石嘉一朗, 川口博明, 笹竹洋, 阿部正治, 牛飼美晴, 有村恵美, 谷本昭英, 堀内正久.
- Organizer
  第86回日本衛生学会学術総会
- Place of Presentation
  旭川市民文化会館（北海道旭川市）
- Year and Date
  2016-05-11
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] マイクロミニピッグの毒性病理2016
- Author(s)
  川口博明, 堀内正久, 谷本昭英
- Organizer
  第43回日本毒性学会学術集会
- Place of Presentation
  ウインクあいち（愛知県産業労働センター）（愛知県名古屋市）
- Year and Date
  2016-06-30
- Invited
- Data Source
  KAKENHI-PROJECT-16K08023
[Presentation] 食事たんぱく質量が2型糖尿病網膜症へ及ぼす影響～レプチン受容体欠損マウスを用いた検討～2016
- Author(s)
  有村恵美、岡谷秀明、荒木智陽、川口博明、中熊美和、阿部正治、牛飼美晴、和泉博之、堀内正久
- Organizer
  第19回日本病態栄養学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-01-09
- Data Source
  KAKENHI-PROJECT-25350873
[Presentation] Deteriorated glucose metabolism with a high-protein,low-carbohydrate diet in db mice, an animal model of a type 2 diabetes, might be caused by insufficient insulin secretion2015
- Author(s)
  Emi Arimura,Wijang Pralampita Pulong, Ancha Caesarina Novi Marchianti, Miwa Nakakuma, Masaharu Abe, Miharu Ushikai, Masahisa Horiuchi
- Organizer
  7th Scientific Meeting of the Asian Association for the Study of Diabetes
- Place of Presentation
  Hong Kong Convention and Exhibition Centreｒ
- Year and Date
  2015-11-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25350873
[Presentation] 低たんぱく食が2型糖尿病の糖代謝・腎機能に及ぼす影響について2012
- Author(s)
  有村恵美, 堀内正久
- Organizer
  第82回日本衛生学会学術総会
- Place of Presentation
  京都大学(京都府)
- Year and Date
  2012-03-25
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] 低たんぱく食が2型糖尿病の糖代謝・腎機能に及ぼす影響:dbマウスを用いた解析2012
- Author(s)
  有村恵美, 堀内正久
- Organizer
  第14回日本病態栄養学会年次学術集会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2012-01-15
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] タンパク質摂取量と腎機能・糖代謝の関わり:dbマウス(2型糖尿病モデル)を用いた解析2011
- Author(s)
  有村恵美, 堀内正久
- Organizer
  第13回日本病態栄養学会年次学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)(招待講演)
- Year and Date
  2011-01-16
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] 世界最小ミニブタの産業医学研究への展開2011
- Author(s)
  堀内正久, ら
- Organizer
  第14回日本病態栄養学会
- Place of Presentation
  佐賀県立男女共同参画センター(佐賀県)
- Year and Date
  2011-07-02
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] カルニチン欠乏ヘテロ接合体マウスは高脂肪食によって肥満傾向を示す2011
- Author(s)
  堀内正久, 武石嘉一朗, ら
- Organizer
  日本衛生学会学術総会
- Place of Presentation
  東京
- Year and Date
  2011-03-27
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 世界最小ミニブタの産業医学研究への展開2011
- Author(s)
  堀内正久
- Organizer
  日本産業衛生学会九州地方会
- Place of Presentation
  佐賀市
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 世界最小ミニブタの栄養学実験への応用2011
- Author(s)
  堀内正久, 川口博明, ら
- Organizer
  日本病態栄養学会
- Place of Presentation
  横浜
- Year and Date
  2011-01-16
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 低蛋白食が2型糖尿病の糖代謝・腎機能に及ぼす影響について2011
- Author(s)
  有村恵美, 堀内正久
- Organizer
  第23回日本糖尿病性腎症研究会
- Place of Presentation
  ベルサーチ神田(東京都)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] 世界最小ミニブタの栄養学実験への応用2011
- Author(s)
  堀内正久、川口博明
- Organizer
  日本病態栄養学会
- Place of Presentation
  横浜市
- Year and Date
  2011-01-16
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] ベンゼンによる発がん機構の検討2011
- Author(s)
  西川拓朗、出雲公子、宮原恵祢子、堀内正久、岡本康裕、河合慶親、河野嘉文、竹内亨
- Organizer
  第10回分子予防環境医学研究会
- Place of Presentation
  京都
- Year and Date
  2011-01-21
- Data Source
  KAKENHI-PROJECT-21659158
[Presentation] ベンゼン発がん機構の再評価2010
- Author(s)
  西川拓朗、出雲公子、堀内正久、岡本康裕、河野嘉文、竹内亨
- Organizer
  第80回日本衛生学会学術総会
- Place of Presentation
  仙台
- Year and Date
  2010-05-10
- Data Source
  KAKENHI-PROJECT-21659158
[Presentation] 蛋白質量が2型糖尿病腎症発症・進展に及ぼす影響:マウスモデル確立と機序解明2010
- Author(s)
  有村恵美, 堀内正久
- Organizer
  第22回日本糖尿病性腎症研究会
- Place of Presentation
  東京慈恵医科大学(東京都)
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] 長期自発運動マウスモデルの確立と習慣的運動の肺への影響解析2010
- Author(s)
  出雲公子, 堀内正久, 竹下温子, 有村恵美, 青山公治, 竹内亨
- Organizer
  第13回日本病態栄養学会
- Place of Presentation
  京都市
- Year and Date
  2010-01-09
- Data Source
  KAKENHI-PROJECT-21659158
[Presentation] 食事タンパク質量が2型糖尿病腎症発症・進農に及ぼす影響:マウスモデル確立と機序解明2010
- Author(s)
  有村恵美, 堀内正久
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22500650
[Presentation] 長期の習慣的な運動が血中アミノ酸に与える影響2009
- Author(s)
  竹下温子、堀内正久、出雲公子、青山公治、竹内亨
- Organizer
  第79回日本衛生学会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 習慣的な自発運動の肺炎予防効果に関する実験的研究:日の遺伝子発現変化からの考察2009
- Author(s)
  堀内正久、出雲公子、竹下温子、川口博明、青山公治、竹内亨
- Organizer
  第7回日本予防医学会学術総会
- Place of Presentation
  千葉市
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 変異原物質による薬剤耐性菌の誘発に関する研究2009
- Author(s)
  宮原恵祢子,内匠正太,宮之原弘晃,西順一郎,吉家清貴,小田紘,小松正治,青山公治,堀内正久,竹内亨
- Organizer
  第79回日本衛生学会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 変異原物質による薬剤耐性菌の誘発に関する研究2009
- Author(s)
  宮原恵弥子, 内匠正太, 宮之原弘晃, 西順一郎, 吉家清貴, 小田紘, 小松正治, 青山公治, 堀内正久, 竹内実, 竹内亨
- Organizer
  第38回日本環境変異原学会
- Place of Presentation
  静岡市
- Year and Date
  2009-11-26
- Data Source
  KAKENHI-PROJECT-21390191
[Presentation] 変異原物質による薬剤耐性菌の誘発に関する研究2009
- Author(s)
  宮原恵祢子, 内匠正太, 宮之原弘晃, 西順一郎, 吉家清貴, 小田紘, 小松正治, 青山公治, 堀内正久, 竹内亨
- Organizer
  日本衛生学会
- Place of Presentation
  東京(北里大学)
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 大学における労働衛生管理の現状2009
- Author(s)
  堀内正久
- Organizer
  平成21年度日本産業衛生学会九州地方会
- Place of Presentation
  那覇市
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 習慣的な自発運動の肺炎予防効果に関する実験的研究:肺の遺伝子発現変化からの考察2009
- Author(s)
  堀内正久, 出雲公子, 竹下温子, 川口博明, 青山公治, 竹内亨
- Organizer
  第7回に本予防医学会学術総会
- Place of Presentation
  千葉市
- Year and Date
  2009-12-13
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 長期の習慣的な運動が血中アミノ酸に与える影響2009
- Author(s)
  竹下温子, 堀内正久, 出雲公子, 青山公治, 竹内亨
- Organizer
  日本衛生学会
- Place of Presentation
  東京(北里大学)
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 習慣的な自発運動の肺炎予防効果に関する実験的研究:肺の遺伝子発現変化からの考察2009
- Author(s)
  堀内正久, 出雲公子, 川口博明, 青山公治, 竹内亨
- Organizer
  平成21年度日本産業衛生学会九州地方会
- Place of Presentation
  那覇市
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 自発運動が肺がん発症に与える影響 : 化学発がんモデルマウスを用いた検討2009
- Author(s)
  出雲公子、堀内正久、川口博明、竹下温子、青山公治、竹内亨
- Organizer
  第79回日本衛生学会
- Place of Presentation
  東京
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 自発運動が肺がん発症に与える影響 : 化学発がんモデルマウスを用いた検討2009
- Author(s)
  出雲公子, 堀内正久, 川口博明, 竹下温子, 青山公治, 竹内亨
- Organizer
  日本衛生学会
- Place of Presentation
  東京(北里大学)
- Year and Date
  2009-03-30
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 大学における労働衛生管理の現状2009
- Author(s)
  堀内正久
- Organizer
  日本産業衛生学会九州地方会
- Place of Presentation
  那覇市
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-21590704
[Presentation] 習慣的運動が発がんに影響を与えるか? : 回転車付きケージと肺がん易発症マウスを用いた評価モデルの確立第2報2008
- Author(s)
  堀内正久, 出雲公子, 川口博明, 青山公治, 竹内亨
- Organizer
  日本予防医学会
- Place of Presentation
  東京(東京医科大学)
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 習慣的運動による遺伝子発現の変動2008
- Author(s)
  米澤千花、出雲公子、坂東健二郎、小松正治、青山公治、堀内正久、松口徹也、竹内亨
- Organizer
  第78回日本衛生学会
- Place of Presentation
  熊本
- Year and Date
  2008-03-31
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 習慣的運動による遺伝子発現の変動2008
- Author(s)
  米澤千花、出雲公子、坂東健二郎、小松正治、青山公治、堀内正久、松口徹也、竹内亨
- Organizer
  第78回日本衛生学会
- Place of Presentation
  熊本市
- Year and Date
  2008-03-31
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 習慣的運動が発がんに影響を与えるか? : 回転車付きケージと肺がん易発症マウスを用いた評価モデルの確立第2報2008
- Author(s)
  堀内正久、出雲公子、川口博明、青山公治、竹内亨
- Organizer
  第6回日本予防医学会
- Place of Presentation
  東京
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] Environmental mutagens as a possible cause for the emergence of drug resistant bacteria2007
- Author(s)
  Nishie M, Takumi S, Miyanohara H, Nishi J, Yoshiie K, Oda h, Komatsu M, Aoyama K, Horiuchi M, Kishi F, Takeuchi M, Takeuchi T
- Organizer
  1st Asian Conference on Environmental Mutagens/36^<th> Annual Meeting of the Japanese Environmental Mutagen Society
- Place of Presentation
  北九州
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 抗老化サプリメント、Dehydroepi-androsterone(DHEA)の安全性に関する研究2007
- Author(s)
  出雲公子、小松正治、青山公治、坂東健二郎、堀内正久、松口徹也、竹内亨
- Organizer
  第77回日本衛生学会
- Place of Presentation
  大阪
- Year and Date
  2007-03-26
- Data Source
  KAKENHI-PROJECT-18390183
[Presentation] 習慣的運動が癌の発症に影響を与えるか- : 回転車付きケージと肺癌易発症マウスを用いた評価、モデルの確立2007
- Author(s)
  堀内正久、出雲公子、川口博明、小松正治、青山公治、竹内亨
- Organizer
  第5回日本予防医学会
- Place of Presentation
  鹿児島
- Year and Date
  2007-11-24
- Data Source
  KAKENHI-PROJECT-18390183

1. SAHEKI Takeyori (10056070)

# of Collaborated Projects: 7 results

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2. USHIKAI Miharu (70232816)

# of Collaborated Projects: 6 results

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3. KAWAGUCHI Hiroaki (60325777)

# of Collaborated Projects: 5 results

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4. TAKEUCHI Toru (00188161)

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5. ARIMURA Emi (40552964)

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10. AOYAMA Kouji (70117472)

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# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
35. IZUMO Kimiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
36. MIYAHARA Emiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
37. Fukushima Syouji

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
38. Kanouchi Hiroaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
39. NOGUCHI michiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
40. OHTAKE masayoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HORIUCHI Masahisa 堀内 正久

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Roles of vitamin B1 in fatty acid metabolism abnormalitiesPrincipal Investigator

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Effects of fat in diets on heterozygous mutants of carnitine-deficient micePrincipal Investigator

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HORIUCHI Masahisa 堀内正久