Shimozawa Nobuhiro 下澤律浩

… Alternative Names

Researcher Number	50300786
Other IDs
External Links
Affiliation (Current)	2020: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所霊長類医科学研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2017 – 2020: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所霊長類医科学研究センター, 主任研究員 2016: 国立研究開発法人医薬基盤・健康・栄養研究所, 資源開発研究室, 研究員 2015 – 2016: 国立研究開発法人医薬基盤・健康・栄養研究所, 霊長類医科学研究センター, 研究員 2013 – 2015: 医薬基盤研究所, 霊長類医科学研究センター, 主任研究員 2014: 独立行政法人医薬基盤研究所, 霊長類医科学研究センター, 研究員 … More
Review Section/Research Field	Principal Investigator Laboratory animal science / Laboratory animal science / Integrative animal science / Basic Section 42040:Laboratory animal science-related Except Principal Investigator Ophthalmology / Laboratory animal science / Surgery related to the biological and sensory functions and related fields / Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator ES細胞 / カニクイザル / クローンマウス / キメラマウス / C57BL / 6J / TT2株 / クローン / 核移植 / 体外培養 … More Except Principal Investigator 医歯薬学 / 外科系臨床医学 / 眼科学 / 眼生化学・分子生物学 / 疾患モデル動物 / カニクイザル / 霊長類 / ノックアウト / 遺伝子改変 / ドルーゼン / 眼性化学・分子生物学 / 実験動物 / クローン動物 / 核移植 / ES細胞 / ミトコンドリア / ヘテロプラスミー / experimental animals / cloned mice / nuclear transfer / embryonic stem cells / mitochondria / CRISPR/Cas9 / 網膜色素変性 / 病院遺伝子検索 Less

Development of research resources in cynomolgus monkeys with neuronal ceroid lipofuscinosisPrincipal InvestigatorOngoing
- Principal Investigator
  
  下澤律浩
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
網膜色素変性を自然発症するカニクイザルの病態解明と繁殖に向けた準備Ongoing
- Principal Investigator
  
  池田康博
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  University of Miyazaki
Derivation of haploid cynomolgus monkey ES cellsPrincipal Investigator
- Principal Investigator
  
  Shimozawa Nobuhiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Construction of Cynomologus Monkey Model for Hereditary Retinal Diseases : Diseases Mechanisms and TherapeuticOngoing
- Principal Investigator
  
  岩田岳
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Development of disease monkey model for hereditary retinal disease by gene editing
- Principal Investigator
  
  Iwata Takeshi
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Primate model to study drusen formation and development of therapeutics
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Development of cynomolgus monkey with hereditary retinal diseases
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Development and pathological characterization of genetically modified macaque monkey with eye disease.
- Principal Investigator
  
  IWATA Takeshi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  独立行政法人国立病院機構(東京医療センター臨床研究センター)
Basic study for production of efficient somatic cell cloned embryosPrincipal Investigator
- Principal Investigator
  
  SHIMOZAWA Nobuhiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  National Institute of Biomedical Innovation
クローンマウスの作出効率に及ぼすES細胞の分化度の影響Principal Investigator
- Principal Investigator
  
  下澤律浩
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals
Generation of cloned mice and application on the field of laboratory animal science
- Principal Investigator
  
  ITO Mamoru
- Project Period (FY)
  1999 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Laboratory animal science
- Research Institution
  Central Institute for Experimental Animals

All 2019 2018 2017 2010 2009

All Journal Article Presentation

[Journal Article] Genome-wide association study identifies seven novel susceptibility loei for primary open-angle glaucoma2018
- Author(s)
  Shiga Y, Akiyama M, Nishiguchi K M, Sato K, Shimozawa N, Takahashi A, Momozawa Y, Hirata M, Matsuda K, Yamaji T, Iwasaki M, Tsugane S, Oze I, Mikami H, Naito M, Wakai K, Yoshikawa M, Miyake M, Yanaka T, et al.
- Journal Title
  
  Human Molecular Genetics
  
  Volume: 27 Issue: 8 Pages: 1486-1496
- DOI
  10.1093/hmg/ddy053
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11478, KAKENHI-PROJECT-17K11482, KAKENHI-PUBLICLY-16H01566, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-18K09400, KAKENHI-PROJECT-17H03596
[Journal Article] KUS121, an ATP regulator, mitigates chorioretinal pathologies in animalmodels of age-related macular degeneration.2018
- Author(s)
  Muraoka, Y., Yoshimura, N., et al.
- Journal Title
  
  Heliyon.
  
  Volume: 4
- DOI
  10.1016/j.heliyon.2018.e00624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24249082, KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-17H06276, KAKENHI-PROJECT-16K11285, KAKENHI-PROJECT-16H05151
[Journal Article] Development of genotyping method for functionally relavant variants of cytochromes P450 in cynomogus macaques.2018
- Author(s)
  Uno Y, Osada N, Sakurai S, Shimozawa N, Iwata T, Ikeo K, Yamazaki H.
- Journal Title
  
  Journal of Veterinary Pharmacology and Therapeutics
  
  Volume: 41
- DOI
  10.1111/jvp.12443
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08146, KAKENHI-PROJECT-17H06276
[Journal Article] Discovery of a cynomolgus monkey family with retinitis pigmentosa.2018
- Author(s)
  Ikeda Yasuhiro、Nishiguchi Koji M.、Miya Fuyuki、Shimozawa Nobuhiro、Funatsu Jun、Nakatake Shunji、Fujiwara Kohta、Tachibana Takashi、Murakami Yusuke、Hisatomi Toshio、Yoshida Shigeo、Yasutomi Yasuhiro、Tsunoda Tatsuhiko、Nakazawa Toru、Ishibashi Tatsuro、Sonoda Koh-Hei
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 59 Pages: 826-826
- DOI
  10.1167/iovs.17-22958
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07211, KAKENHI-PROJECT-17K08146
[Journal Article] 人為的な生殖技術を用いたカニクイザルの作出2017
- Author(s)
  下澤律浩
- Journal Title
  
  基礎老化研究
  
  Volume: 41 Pages: 17-22
- Data Source
  KAKENHI-PROJECT-17K08146
[Journal Article] Characterization of a novel embryonic stem cell line from an intracytoplasmic sperm in jection-derived blastocyst in the African green monkey.2010
- Author(s)
  Shimozawa N, Nakamura S, Takahashi I, Hatori M, Sankai T.
- Journal Title
  
  139
  
  Pages: 565-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700455
[Journal Article] Characterization of a novel embryonic stem cell line from an intracytoplasmic sperm injection-derived blastocyst in the African green monkey.2010
- Author(s)
  Shimozawa N, Nakamura S, Takahashi I, Hatori M, Sankai T
- Journal Title
  
  Reproduction
  
  Volume: 139 Pages: 565-573
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700455
[Presentation] 霊長類科学研究センターで認められた神経セロイドリポフスチノーシスの原因遺伝子同定とコロニー内保因状況2019
- Author(s)
  棟居佳子、下澤律浩、高橋一朗、岡林　佐知、揚山直英、木村展之、片貝祐子、八神健一、保富康宏
- Organizer
  第28回サル類疾病ワークショップ
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] カニクイザルに適した卵採取法の検討2019
- Author(s)
  下澤律浩
- Organizer
  第60回日本卵子学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] カニクイザルにおける人工授精の検討2019
- Author(s)
  下澤律浩
- Organizer
  第28回サル類疾病ワークショップ
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] 神経セロイドリポフスチン症カニクイザルの発見とリソース開発2019
- Author(s)
  下澤律浩
- Organizer
  第23回一般社団法人予防衛生協会セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] カニクイザル一倍体ES細胞の樹立に関する検討2019
- Author(s)
  下澤律浩
- Organizer
  第66回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] 神経症状の異常を呈するカニクイザルにおける原因遺伝子の同定と保因状況に関する調査2018
- Author(s)
  下澤律浩、高橋一朗、棟居桂子、木村展之、揚山直英、片貝祐子、八神健一、保富康宏
- Organizer
  第65回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] 実験用カニクイザル繁殖コロニー内で見られた遺伝性の神経セロイドリポフスチノーシス2018
- Author(s)
  棟居佳子、岡林　佐知、下澤律浩、高橋一朗、木村展之、揚山直英、片貝祐子、八神健一、保富康宏
- Organizer
  第65回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] 神経セロイドリポフスチノーシスを発症したカニクイザル2018
- Author(s)
  下澤律浩、棟居佳子、高橋一朗、岡林佐知、木村展之、片貝祐子、揚山直英、八神健一、保富康宏
- Organizer
  第23回日本ライソゾーム病研究会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] サル心臓内の軸索末端追跡の試み：バーチャルスライドを用いた厚い切片の網羅的検討2017
- Author(s)
  新宅　洋、下澤律浩、近藤ひろみ、横田隆徳、内原俊記
- Organizer
  第５８回神経病理学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] PSP/CBDモデルとしての高齢サル脳のタウ沈着2017
- Author(s)
  内原俊記、遠藤堅太郎、近藤ひろみ、岡林佐知、下澤律浩、保富康宏、安達栄治郎、木村展之
- Organizer
  第５８回神経病理学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] Inherited retinal degeneration in the cynomolgus monkey (Macaca fascicularis).2017
- Author(s)
  Ikeda Y, Shimozawa N, Nishiguchi KM, FunatsuJ, Nakatake S, Fujiwara K, Tachibana T, Murakami Y, Hisatomi T, Yoshida S, Ishibashi T, Sonoda K.
- Organizer
  The Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] GnRH antagonistを用いたカニクイザル卵巣刺激法の検討2017
- Author(s)
  下澤律浩
- Organizer
  第64回日本実験動物学会
- Data Source
  KAKENHI-PROJECT-17K08146
[Presentation] カニクイザル体細胞に由来する人工多能性幹細胞の作製2010
- Author(s)
  下澤律浩、高橋一朗、柴田宏昭、小埜良一、伊奈田宏康、野阪哲哉、保富康宏
- Organizer
  第57回日本実験動物学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21700455
[Presentation] カニクイザル胚性幹細胞株の神経細胞分化誘導におけるFGF2の影響2009
- Author(s)
  羽鳥真功、Fowzia Sultana、下澤律浩、八神健一、山海直
- Organizer
  第56回日本実験動物学会
- Place of Presentation
  大宮ソニックシティ(埼玉県)
- Data Source
  KAKENHI-PROJECT-21700455
[Presentation] カニクイザル胚性幹細胞株の神経細胞分化誘導におけるFGF2の影響2009
- Author(s)
  羽鳥真功、Fowzia Sultana、下澤律浩、八神健一、山海直
- Organizer
  第56回日本実験動物学会
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-21700455

1. IWATA Takeshi (90374157)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. MIZOTA Atsushi (10239262)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
3. ITO Mamoru (00176364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HIOKI Kyoji (80208735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. IMAI Hiroshi (10303869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KONO Tomohiro (80153485)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TANIOKA Yoshikuni (10072406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 高橋一朗 (90171470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
9. 揚山直英 (50399458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 池田康博 (20380389)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 西口康二 (30447825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MIKAMI Haruo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. NAITO Mariko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 柏木賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 木内良明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 高橋隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 若井健志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 間渕文彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 平田真

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 吉村長久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 池田華子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 村岡勇貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 畑匡侑

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 垣塚彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 宮冬樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shimozawa Nobuhiro 下澤 律浩

SHIMOZAWA Nobuhiro 下澤 律浩

SHIMOZAWA Norihiro 下澤 律浩

Research Projects

Research Products

Co-Researchers

Development of research resources in cynomolgus monkeys with neuronal ceroid lipofuscinosisPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

網膜色素変性を自然発症するカニクイザルの病態解明と繁殖に向けた準備Ongoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Derivation of haploid cynomolgus monkey ES cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Construction of Cynomologus Monkey Model for Hereditary Retinal Diseases : Diseases Mechanisms and TherapeuticOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of disease monkey model for hereditary retinal disease by gene editing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Primate model to study drusen formation and development of therapeutics

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of cynomolgus monkey with hereditary retinal diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development and pathological characterization of genetically modified macaque monkey with eye disease.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study for production of efficient somatic cell cloned embryosPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

クローンマウスの作出効率に及ぼすES細胞の分化度の影響Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Generation of cloned mice and application on the field of laboratory animal science

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Genome-wide association study identifies seven novel susceptibility loei for primary open-angle glaucoma2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KUS121, an ATP regulator, mitigates chorioretinal pathologies in animalmodels of age-related macular degeneration.2018

Author(s)

Journal Title

Shimozawa Nobuhiro 下澤律浩

SHIMOZAWA Nobuhiro 下澤律浩

SHIMOZAWA Norihiro 下澤律浩