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Takagi Norio  高木 教夫

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TAKAGI Norio  高木 教夫

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Researcher Number 50318193
Other IDs
Affiliation (Current) 2025: 東京薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 東京薬科大学, 薬学部, 教授
2013 – 2019: 東京薬科大学, 薬学部, 教授
2008 – 2013: Tokyo University of Pharmacy and Life Science, 薬学部, 准教授
2010: Tokyo University of Pharmacy and Life Science, 薬学, 教授
2005 – 2007: 東京薬科大学, 薬学部, 講師
2003 – 2004: 東京薬科大学, 薬学部, 助手
1999 – 2001: 東京薬科大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Biological pharmacy / Neurochemistry/Neuropharmacology / Basic Section 59040:Nutrition science and health science-related / Neurochemistry/Neuropharmacology
Except Principal Investigator
Medical systems / Medical systems / Basic Section 09050:Tertiary education-related / Medical pharmacy / General pharmacology
Keywords
Principal Investigator
脳虚血 / チロシンリン酸化 / 脳血管 / 情報伝達 / NMDA受容体 / 脳梗塞 / 血液脳関門 / タンパク質間相互作用 / 血管性認知症 / 脳血管周囲 … More / 生活習慣病 / LRP1 / グルタミン酸受容体 / Occludin / タイトジャンクション / チロシンキナーゼ / 活性酸素種 / タンパク質相互作用 … More
Except Principal Investigator
超音波 / バブルリポソーム / リポソーム / GAP-43 / BDNF / 超音波照射 / 遺伝子導入 / Institutional Research / IR / 6年制 / 薬剤師 / 就職 / キャリア / 教育評価 / 薬学 / 6年制 / 卒論研究 / 卒業論文 / コンピテンス / 薬学教育 / ヒ素化合物 / MDA-MB-231 / MCF-7 / 薬物トランスポーター / オートファジー / テトランドリン / 亜ヒ酸化合物 / 乳がん / ドラッグデリバリーシステム / ナノ材料 / 生理活性ガス / セラノスティクス / 一酸化窒素ガス / ナノバブル / TYROSINE PHOSPHORYLATION OF G PROTEIN / ACETYLCHOLINE / CEREBROVASCULAR DEMENTIA / CELL ADHESION MOLECULE / NERVE GROWTH FACTOR / REGENERATION OF THE NEURONAL NETWORK / コリンアセチルトランスフェラーゼ / MAP-2 / シナプトフィジン / マイクロスフェア塞栓 / 脳血管性痴呆症 / Gタンパク質チロシンリン酸化 / アセチルコリン / 脳血管性痴呆 / 神経接着因子 / 神経成長因子 / 神経回路再生 / 核酸・遺伝子デリバリー / 血液脳関門 / 集束超音波 / アンチセンス / ジストロフィン / 筋ジストロフィー / 遺伝子細胞療法 / ペプチド修飾リポソーム / 遺伝子治療 / 超音波造影ガス封入リポソーム / 新生血管 / リボソーム / 遺伝子道入 / 血管再生 / 超音波造影 Less
  • Research Projects

    (16 results)
  • Research Products

    (53 results)
  • Co-Researchers

    (31 People)
  •  生活習慣病を伴う脳梗塞後の脳血管に着目したNAMPTの機能解析Principal Investigator

    • Principal Investigator
      高木 教夫
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  6年制導入に伴う薬学教育のジレンマとその解消策-東薬の経験と他大学の比較-

    • Principal Investigator
      別生 伸太郎
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 09050:Tertiary education-related
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Functional changes in LRP1 in neurons after cerebral infarction and therapeutic strategiesPrincipal Investigator

    • Principal Investigator
      Takagi Norio
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Development of ultrasound-responsive nanobubbles containing physiologically active gas and construction of disease treatment system

    • Principal Investigator
      Negishi Yoichi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical systems
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Fundamental research of application of arsenic compound in combination with tetrandrine to combat breast cancer

    • Principal Investigator
      Yuan Bo
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Medical pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Ultrasound-mediated gene delivery system into brain tissue by blood brain barrier targeting Bubble liposomes

    • Principal Investigator
      Yoichi NEGISHI
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical systems
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Therapeutic systems of muscular dystrophy by morpholino oligonucleotide-loaded nanobubble and ultrasound

    • Principal Investigator
      NEGISHI yoichi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical systems
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Protein tyrosine phosphorylation in the neurovascular unit in cerebrovascular disease and therapeutic strategiesPrincipal Investigator

    • Principal Investigator
      TAKAGI Norio
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Gene transfer system into mesenchymal stem cell by peptide-modified liposomes and ultrasound technology

    • Principal Investigator
      NEGISHI Yoichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical systems
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Low invasive therapeutic system for vascular diseases by neovascular specific liposomes containing US-contrast gas

    • Principal Investigator
      NEGISHI Yoichi
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical systems
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  Molecular basis of cerebrovascular disease with protein tyrosine phosphorylation in brain capillaries and therapeutic strategiesPrincipal Investigator

    • Principal Investigator
      TAKAGI Norio
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  新規な超音波造影ガス封入リポソームによる非侵襲的虚血性血管再生療法のシステム開発

    • Principal Investigator
      NEGISHI Yoichi
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Medical systems
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  脳梗塞病態の分子基盤としてのNMDA受容体チロシンリン酸化とその制御に関する研究Principal Investigator

    • Principal Investigator
      高木 教夫
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  代謝型グルタミン酸受容体を介する脳虚血後のNMDA受容体チロシンリン酸化の研究Principal Investigator

    • Principal Investigator
      高木 教夫
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  脳虚血後のNMDA受容体チロシンリン酸化と細胞内情報伝達に関する研究Principal Investigator

    • Principal Investigator
      高木 教夫
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Tokyo University of Pharmacy and Life Science
  •  STUDIES ON REGENERATION OF THE NEURONAL NETWORK IN CEREBROVASCULAR DEMENTIA MODEL

    • Principal Investigator
      TAKEO Satosi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCE

All 2020 2019 2018 2017 2016 2015 2014 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Other

  • [Journal Article] Furin-mediated cleavage of LRP1 and increase in ICD of LRP1 after cerebral ischemia and after exposure of cultured neurons to NMDA2019

    • Author(s)
      Yamada Mariko、Hayashi Hideki、Suzuki Kaori、Sato Shoko、Inoue Daisuke、Iwatani Yui、Ohata Meiko、Yuan Bo、Takagi Norio
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 11782-11782

    • DOI

      10.1038/s41598-019-48279-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07376, KAKENHI-PROJECT-17K08289
  • [Journal Article] Furin inhibitor protects against neuronal cell death induced by activated NMDA receptors2018

    • Author(s)
      Yamada Mariko、Hayashi Hideki、Yuuki Moe、Matsushima Nahoko、Yuan Bo、Takagi Norio
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1

    • DOI

      10.1038/s41598-018-23567-0

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Journal Article] Protein tyrosine phosphorylation in the ischemic brain2014

    • Author(s)
      Takagi N
    • Journal Title

      J. Pharmacol. Sci

      Volume: (accepted)

    • NAID

      130004677799

    • Data Source
      KAKENHI-PROJECT-23590114
  • [Journal Article] Effects of metabotropic glutamate mGlu5 receptor antagonist on tyrosine phosphorylation of NMDA receptor subunits and cell death in the hippocampus after brain ischemia in rats2012

    • Author(s)
      Takagi N, Besshoh S, Marunouchi T, Takeo S, Tanonaka K
    • Journal Title

      Neurosci. Lett

      Volume: 530 Pages: 91-961

    • Data Source
      KAKENHI-PROJECT-23590114
  • [Journal Article] NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion2011

    • Author(s)
      Murotomi K, Takagi N, Takeo S, Tanonaka K?
    • Journal Title

      Mol.Cell.Neurosci.

      Volume: 46 Pages: 681-688

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] Delivery of an angiogenic gene into ischemic muscle by novel bubble liposomes followed by ultrasound exposure.2011

    • Author(s)
      Y.Negishi, K.Matsuo, Y.Endo-Takahashi, K.Suzuki, Y.Matsuki, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
    • Journal Title

      Pharm.Res.

      Volume: 28 Pages: 712-719

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Journal Article] NADPH oxidase-mediated oxidative damage to proteins in the postsynaptic density after transient cerebral ischemia and reperfusion.2011

    • Author(s)
      Murotomi K, Takagi N, Takeo S, Tanonaka K
    • Journal Title

      Mol.Cell.Neurosci. 46(3)(corresponding author)

      Pages: 681-688

    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] Delivery of an Angiogenic Gene into Ischemic Muscle by Novel Bubble Liposomes Followed by Ultrasound Exposure.2011

    • Author(s)
      Negishi Y, Matsuo K, Endo-Takahashi Y, Suzuki K, Matsuki Y, Takagi N, Suzuki R, Maruyama K, Aramaki Y
    • Journal Title

      Pharm.Res. 28

      Pages: 712-719

    • Data Source
      KAKENHI-PROJECT-20300179
  • [Journal Article] Prostanoid EP1 receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia.2010

    • Author(s)
      Fukumoto K, Takagi N, Yamamoto R, Moriyama Y, Takeo S, Tanonaka K
    • Journal Title

      Eur.J.Pharmacol. 640(1-3)(corresponding author)

      Pages: 82-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] Prostanoid EP1 receptor antagonist reduces blood-brain barrier leakage after cerebral ischemia.2010

    • Author(s)
      Fukumoto K, Takagi N, Yamamoto R, Moriyama Y, Takeo S, Tanonaka K
    • Journal Title

      Eur.J.Pharmacol.

      Volume: 640 Pages: 82-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] mGluR1 antagonist decreased NADPH oxidase activity and superoxide production after transient focal cerebral ischemia.2010

    • Author(s)
      Murotomi K, Takagi N, Mizutani R, Honda T, Ono M, Takeo S, Tanonaka K
    • Journal Title

      J.Neurochem. 114(corresponding author)

      Pages: 1711-1719

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] Ultrasound Imaging and Gene Delivery by AG73-modified Bubble Liposomes2009

    • Author(s)
      Y. Negishi, Y. Tsunoda, N. Hamano, Y. Endo, N. Takagi, R. Suzuki, K, Maruyama, C. Batsuren, M. Emoto, M. Nomizu, Y. Aramaki
    • Journal Title

      Peptide Science 2008

      Pages: 127-130

    • NAID

      10027166068

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Journal Article] Ultrasound imaging and gene delivery by AG73-modified bubble liposomes2009

    • Author(s)
      Negishi Y, Tsunoda Y, Endo Y, Takagi N, Suzuki R, Maruyama K, Emoto M, Nomizu M, Aramaki A
    • Journal Title

      Peptide Science 2008

      Pages: 127-130

    • NAID

      10027166068

    • Data Source
      KAKENHI-PROJECT-20300179
  • [Journal Article] Inhibition of src activity decreases tyrosine phosphorylation of occludin in brain capillaries and attenuates increase in permeability of the blood-brain barrier after transient focal cerebral ischemia.2009

    • Author(s)
      Takenaga Y, Takagi N, Murotomi K, Tanonaka K, Takeo S
    • Journal Title

      J.Cereb.Blood Flow Metab. 29(6)(corresponding author)

      Pages: 1099-1108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] Inhibition of src activity decreases tyrosine phosphorylation of occludin in brain capillaries and attenuates increase in permeability of the blood-brain barrier after transient focal cerebral ischemia.2009

    • Author(s)
      Takenaga Y, Takagi N, Murotomi K, Tanonaka K, Takeo S
    • Journal Title

      Journal of Cerebral Blood Flow and Metabolism 29

      Pages: 1099-1108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] mGluRl antagonist decreases tyrosine phosphorylation of NMDA receptor and attenuates infarct size after transient focal cerebral ischemia.2008

    • Author(s)
      Murotomi K, Takagi N, Takayanagi G, Ono M, Takeo S, Tanonaka
    • Journal Title

      Journal of Neurochemistry 105

      Pages: 1625-1634

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Journal Article] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis

    • Author(s)
      Negishi Y, Endo-Takahashi Y, Takagi N, Suzuki R, Maruyama K, Aramaki Y
    • Journal Title

      10th International Symposium Therapeutic Ultrasound. AIP Conf.Proc. (in press)

    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] 虚血性脳神経障害によるLRP1切断と細胞内ドメインの産生2020

    • Author(s)
      岩谷結衣,山田まりこ,鈴木かおり,林秀樹,高木教夫
    • Organizer
      第93回 日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 虚血性脳神経障害時のLRP1プロセシングと神経細胞死の関連2019

    • Author(s)
      今村唯、堀之北一朗、林 秀樹、高木 教夫
    • Organizer
      第140回 日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] Effects of furin inhibitors on excitotoxic neuronal damage2019

    • Author(s)
      M. Yamada, H. Hayashi, M. Ichiyanagi, Y. Imamura, B. Yuan, N. Takagi
    • Organizer
      第92回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 虚血性神経障害時のLRP1の変化と神経保護の可能性2018

    • Author(s)
      山田まりこ、林 秀樹、岩谷結衣、鈴木かおり、袁 博、高木 教夫
    • Organizer
      日本薬学会 第138年会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 虚血性神経障害時の LRP1 の変化と神経保護の可能性2018

    • Author(s)
      山田まりこ,林秀樹,岩谷結衣,鈴木かおり,袁博,高木教夫
    • Organizer
      日本薬学会 第138年会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 虚血性神経障害時の LRP1 プロセシングと神経生存2018

    • Author(s)
      山田 まりこ、林 秀樹、井上 大輔、大畑 芽衣子、松嶋 菜穂子、袁 博、高木 教夫
    • Organizer
      第60回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] Pathologic roles of proteolytic enzymes associated with receptor processing2017

    • Author(s)
      Mariko Yamada, Hideki Hayashi, Nahoko Matsushima, Meiko Ohata, Bo Yuan, Norio Takagi
    • Organizer
      Neuroscience 2017, Society for Neuroscience
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 初代培養大脳皮質神経細胞障害時の LRP1 の変化とリポプロテイン による神経保護への可能性2017

    • Author(s)
      山田 まりこ、佐藤 祥子、結城 もえ、袁 博、林 秀樹、高木 教夫
    • Organizer
      第59回 日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 初代培養大脳皮質神経細胞障害時のproprotein convertasesの役割に関する研究2017

    • Author(s)
      岩谷結衣、鈴木かおり、山田まりこ、林 秀樹、袁 博、高木教夫
    • Organizer
      第138回 日本薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] 中枢神経細胞障害時の LRP1 プロセッシングに関わるタンパク質分解酵素と神経生存2017

    • Author(s)
      山田 まりこ、林 秀樹、井上大輔、岩谷結衣、鈴木かおり、袁 博、高木 教夫
    • Organizer
      第90回 日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-17K08289
  • [Presentation] In vitroおよびin vivoで乳がん細胞 MDA-MB-231に対するAsIIIとテトランドリンの 単独・併用による抗腫瘍活性2016

    • Author(s)
      王 瀟,姚 明江,袁 博,林 秀樹,高木 教夫
    • Organizer
      第22回ヒ素シンポジウム
    • Place of Presentation
      国立研究開発法人産業技術総合研究所 臨海副都心センター別館11階
    • Year and Date
      2016-11-17
    • Data Source
      KAKENHI-PROJECT-26460233
  • [Presentation] Antitumor activity of arsenite and tetrandrine, each alone and in combination, against breast cancer cell line MDA-MB-231 in vitro and in vivo2016

    • Author(s)
      Xiao Wang, Mingjiang Yao, Bo Yuan, Hideki Hayashi, Norio Takagi
    • Organizer
      第136回日本薬学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-03-26
    • Data Source
      KAKENHI-PROJECT-26460233
  • [Presentation] バブルリポソームと高密度集束超音波併用による脳内へのアンチセンス核酸・遺伝子デリバリー2015

    • Author(s)
      根岸洋一、栗原奈保、髙橋葉子、指田紗菜恵、高木教夫、鈴木 亮、丸山一雄、新槇幸彦
    • Organizer
      日本核酸医薬学会 第1回年会
    • Place of Presentation
      京都テルサ(京都府京都市)
    • Year and Date
      2015-11-30
    • Data Source
      KAKENHI-PROJECT-25560240
  • [Presentation] ナノバブルと高密度集束超音波併用による血液脳関門透過性亢進と脳内遺伝子デリバリー2015

    • Author(s)
      根岸洋一、髙橋葉子、栗原 奈保、鈴木 亮、丸山 一雄、高木教夫、新槇 幸彦
    • Organizer
      第14回日本超音波治療研究会
    • Place of Presentation
      高知市文化プラザかるぽーと(高知県高知市)
    • Year and Date
      2015-11-28
    • Data Source
      KAKENHI-PROJECT-25560240
  • [Presentation] ナノバブルと集束超音波併用による脳内分子デリバリーシステムの構築2015

    • Author(s)
      根岸洋一、栗原奈保、髙橋葉子、鈴木 亮、丸山一雄、高木教夫、新槇幸彦
    • Organizer
      遺伝子・デリバリー研究会 第15回シンポジウム
    • Place of Presentation
      京都薬科大学(京都府山科区)
    • Year and Date
      2015-05-01
    • Data Source
      KAKENHI-PROJECT-25560240
  • [Presentation] Enhanced Antitumor Effect of the Combination of Arsenite with Tetrandrine in Breast Cancer2015

    • Author(s)
      Mingjiang Yao, Xiao Wang, Bo Yuan, Ai Sato, Kana Sakuma, Kurumi Kaneko, Hideki Hayashi, Hiroo Toyoda, Norio Takagi
    • Organizer
      BMB2015(第38回日本分子生物学会・第88回日本生化学会 合同大会)
    • Place of Presentation
      神戸
    • Year and Date
      2015-12-01
    • Data Source
      KAKENHI-PROJECT-26460233
  • [Presentation] アニオン性脂質含有バブルリポソームと高密度集束超音波による血液脳関門透過性亢進と脳内遺伝子デリバリー2015

    • Author(s)
      栗原奈保、根岸洋一、山根正也、山垣内貴文、髙橋葉子、高木教夫、鈴木 亮、丸山一雄、新槇幸彦
    • Organizer
      日本薬剤学会 第30年会
    • Place of Presentation
      長崎ブリックホール(長崎県長崎市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-25560240
  • [Presentation] バブルリポソームと高密度集束超音波併用による血液脳関門透過性亢進に関する基礎的検討2014

    • Author(s)
      山根 正也, 根岸洋一, 栗原 奈保, 髙橋葉子, 鈴木 亮, 丸山 一雄, 高木 教夫, 新槇 幸彦
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本
    • Data Source
      KAKENHI-PROJECT-25560240
  • [Presentation] DOTAP含有バブルリポソームによる全身循環を介した下肢虚血部位への超音波遺伝子導入法の検討2011

    • Author(s)
      松木勇樹, 根岸洋一, 高橋葉子, 加藤妥治, 高山華奈, 高木教夫, 鈴木亮, 丸山一雄, 新槇幸彦
    • Organizer
      日本薬学会第131年会
    • Place of Presentation
      静岡
    • Year and Date
      2011-03-28
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] NADPH oxidaseは一過性局所脳虚血後のシナプス後肥厚部関連タンパク質の酸化障害に寄与する2011

    • Author(s)
      室冨和俊、高木教夫、田野中浩一
    • Organizer
      第84回 日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Presentation] バブルリポソーム併用超音波遺伝子デリバリーシステムの疾患治療への応用2011

    • Author(s)
      根岸洋一,高橋葉子,高木教夫,鈴木亮,丸山一雄,新槇幸彦
    • Organizer
      第3回 超音波とマイクロバブルの相互作用に関するシンポジウム
    • Place of Presentation
      東京(招待講演)
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] NADPH oxidaseは一過性局所脳虚血後のシナプス後肥厚部関連タンパク質の酸化障害に寄与する2011

    • Author(s)
      室冨和俊、高木教夫、田野中浩一
    • Organizer
      第84回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2011-03-22
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Presentation] バブルリポソーム併用超音波遺伝子デリバリーシステムの疾患治療への応用2011

    • Author(s)
      根岸洋一, 高橋葉子, 高木教夫, 鈴木亮, 丸山一雄, 新槇幸彦
    • Organizer
      第3回超音波とマイクロバブルの相互作用に関するシンポジウム
    • Place of Presentation
      横浜
    • Year and Date
      2011-01-22
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] bFGF Gene Transfer into Skeletal Muscle of Hindlimb Ischemia Model by Bubble Liposome and Ultrasound2010

    • Author(s)
      Y.Negishi, Y.Endo-Takahashi, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
    • Organizer
      International Liposome Research Days and Lipids, Liposomes, & Membrane Biophysics
    • Place of Presentation
      University of British Columbia (Vancouver)
    • Year and Date
      2010-08-04
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] バブルリポソームと超音波技術の融合による下肢虚血モデルへのbFGF/SDF-1遺伝子導入効果の解析2010

    • Author(s)
      根岸洋一,鈴木健太郎,遠藤葉子,高木教夫,鈴木亮,丸山一雄,新槇幸彦
    • Organizer
      第9回日本再生医療学会総会
    • Place of Presentation
      広島
    • Year and Date
      2010-03-19
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis2010

    • Author(s)
      Y.Negishi, K. Matsuo, Y. Endo-Takahashi, K. Suzuki, Y. Matsuki, N. Takagi, R. Suzuki, K.Maruyama, Y.Aramaki,
    • Organizer
      10th International Symposium on Therapeutic Ultrasound
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-06-10
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] 一過性局所脳虚血後のNADPH oixdaseを介したスーパーオキシド産生におけるmGluR1の関与2010

    • Author(s)
      室冨和俊,高木教夫,大野恵美,水谷玲子,竹尾聰,田野中浩一
    • Organizer
      第83回日本薬理学会年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-16
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Presentation] bFGF Gene Transfer into Skeletal Muscle of Hindlimb Ischemia Model by Bubble Liposome and Ultrasound, International Liposome Research Days and Lipids2010

    • Author(s)
      Y. Negishi, Y. Endo-Takahashi, N. Takagi, R.Suzuki, K. Maruyama, Y. Aramaki,
    • Organizer
      Liposomes, & Membrane Biophysics
    • Place of Presentation
      Vancouver
    • Year and Date
      2010-08-04
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] Intramuscular Injection of Angiogenic Gene with Bubble Liposomes Followed by Ultrasound Exposure to Improve Angiogenesis2010

    • Author(s)
      Y.Negishi, K.Matsuo, Y.Endo-Takahashi, K.Suzuki, Y.Matsuki, N.Takagi, R.Suzuki, K.Maruyama, Y.Aramaki
    • Organizer
      10^<th> International Symposium on Therapeutic Ultrasound
    • Place of Presentation
      Tokyo
    • Year and Date
      2010-06-10
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] 一過性局所脳虚血後のoccludinチロシンリン酸化と血液脳関門破綻へのSrcの関与2009

    • Author(s)
      室冨和俊,高木教夫,竹永悠司,竹尾聰,田野中浩一
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-03-16
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Presentation] 超音波技術を利用した下肢虚血モデルへのbFGF/SDF-1遺伝子導入効果の解析2009

    • Author(s)
      根岸洋一,松尾慶子,遠藤葉子,鈴木健太郎,高木教夫,鈴木亮,丸山一雄,新槇幸彦
    • Organizer
      日本薬剤学会第24年会
    • Place of Presentation
      静岡
    • Year and Date
      2009-05-21
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] Gene Transfer of bFGF into Skeletal Muscle of Murine Hindlimb Ischemia Model by Echo-contrast Gas Entrapping Liposomes2008

    • Author(s)
      K. Matsuo, Y. Negishi, Y. Endo-Takahashi, N. Takagi, R. Suzuki, K. Maruyama, Y.Aramaki
    • Organizer
      Bubble liposomes and Ultrasound 11th Liposome Research Days Conference
    • Place of Presentation
      横浜
    • Year and Date
      2008-07-18
    • Data Source
      KAKENHI-PROJECT-20300179
  • [Presentation] Inhibition of protein tyrosine kinase prevents disruption of blood brain barrier and attenuates infarct size after transient focal cerebral ischemia2008

    • Author(s)
      K.Murotomi, N.Takagi, Y.Takenaga, S.Takeo, K.Tanonaka
    • Organizer
      第51回日本神経化学大会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-11
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Presentation] 虚血性脳障害の病態解析と治療戦略2008

    • Author(s)
      高木教夫
    • Organizer
      第52回日本薬学会関東支部大会
    • Place of Presentation
      千葉
    • Year and Date
      2008-01-04
    • Data Source
      KAKENHI-PROJECT-20590091
  • [Presentation] Enhancement of Blood-Brain Barrier Permeability by the Combination of Bubble Liposomes and High-intensity focused ultrasound

    • Author(s)
      Yoichi Negishi, Masaya Yamane, Naho Kurihara, Endo-Takahashi Yoko, Norio Takagi, Ryo Suzuki, Kazuo Maruyama, Yukihiko Aramaki
    • Organizer
      Focused Ultrasound 2014 - 4th International Symposium
    • Place of Presentation
      Bethesda, USA
    • Year and Date
      2014-10-12 – 2014-10-17
    • Data Source
      KAKENHI-PROJECT-25560240
  • []

  • 1.  MARUYAMA Kazuo (30130040)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 21 results
  • 2.  NEGISHI Yoichi (50286978)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 21 results
  • 3.  TAKAHASHI Yoko (30453806)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 21 results
  • 4.  ARAMAKI Yukihiko (90138959)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 15 results
  • 5.  NOMIZU Motoyoshi (00311522)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  DAIKI OMATA
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  HAMANO NOBUHITO
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  TAKEO Satosi (00136722)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SUZUKI RYO (90384784)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  MARUYAMA TORU (90423657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  Yuan Bo (10328552)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 12.  別生 伸太郎 (20408686)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  三浦 典子 (30218036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  黒田 明平 (80266890)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  鯉沼 卓真 (60910750)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TSUNODA YUKA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 17.  MATSUO KEIKO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 18.  MATSUKI YUKI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 19.  TANONAKA Kouichi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  MARUNOUCHI Tetsuro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  KATAGIRI Fumihiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  ISHII Yuko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  OGURI Yukiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  SHIONO Hitomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  AKIYAMA Saki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  MAYAMA Sayaka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  KIKUCHI Taiki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  ISHIMA YU
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  SAWADA HONOKA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  SASAYAMA MIZUKI
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  HAYASHI Hodeki
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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