OHASHI Kentaro 大橋憲太郎

… Alternative Names

Kentaro Oh-hashi 大橋憲太郎

OH-HASHI Kentaro 大橋憲太郎

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Researcher Number	50332953
Other IDs
Affiliation (Current)	2025: 岐阜大学, 工学部, 教授
Affiliation (based on the past Project Information) *help	2025: 岐阜大学, 工学部, 教授 2014 – 2024: 岐阜大学, 工学部, 准教授 2023: 岐阜大学, 工学部, 教授 2013: 岐阜大学, 工学部, 助教 2007 – 2010: 岐阜大学, 工学部, 助教 … More 2004 – 2006: 岐阜大学, 工学部, 助手 2003: 京都府立医科大学, 医学研究科, 助手 2001 – 2002: 京都府立医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields / Health science and related fields / Neurochemistry/Neuropharmacology / Biological pharmacy / General anatomy (including Histology/Embryology) Except Principal Investigator Basic Section 55050:Anesthesiology-related / Anesthesiology / General internal medicine(including psychosomatic medicine) / Basic Section 53040:Nephrology-related … More / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Surgery of the organs maintaining homeostasis and related fields / Developmental biology / Neuroscience in general / Nerve anatomy/Neuropathology / Neurochemistry/Neuropharmacology Less
Keywords	Principal Investigator 小胞体ストレス / ERAD / ERストレス / FAM134B / CREB3 / ゴルジ体ストレス / TFE3 / ATF6/CREB3ファミリー / CREB3L2 / CREB3ファミリー … More / 小胞体関連分解 / FAM143B / ATF6/CREB3 family / CREB3 family / 小胞体 / オートファジー / Golgi stress / ER stress / ER-phagy / NanoLuc / SEL1L / IRE1 / ゲノム編集 / 神経変性疾患 / 神経栄養因子 / CRELD2 / MANF / ATF6 / GFAP / グリア細胞 / two-hybrid法 / マイクロアレイ / 神経細胞 / GRP78 / GRP78結合タンパク質 / GFP / PKD / INV / 多発性膿疱腎 / 内臓逆位 / cell cycle / growth arrest / 左右非対称 / PKD2 / 多発性嚢胞腎 … More Except Principal Investigator 痛覚過敏 / ミトコンドリア / 自然免疫 / 慢性痛 / 一次知覚神経 / GRK2 / inv / NPFF / RFRP3 / RFRP1 / 生活習慣病 / メタボリックシンドローム / インスリンシグナル / 脂肪肝 / ERストレス / GADD34 / 老化 / モデルマウス / メサンギウム細胞 / 腎疾患 / 先天代謝異常症 / 極長鎖脂肪酸 / CD22 / ペルオキシソーム形成異常症 / 分子シャペロン / CADASIL変異 / 脳小血管病CADASIL / NOTCH3 / O型糖鎖 / 慢性疼痛 / 炎症性ミトコンドリア障害 / Mitochondria / アレスチン / 細胞膜 / 糖尿病 / 脂質二重膜 / インスリンシグナリング / ストレス応答 / 糖質 / 鶏卵 / 後根神経節 / 神経炎症 / インフラマソーム / microarray / kidney / cyst / 腎臓 / policystin / 繊毛 / 遺伝子発現 / カルシウム / 嚢胞腎 / TARGET GENES / GENOME / NEURON / TRANSCRIPTION / 発生 / 遺伝子 / 分化 / 転写制御 / 標的遺伝子 / ゲノム / 神経 / 転写 / hypothalamus / c-Fos / Rfamide related peptide / 神経内分泌 / 視床下部 / カテコールアミン / 免疫組織化学 / RFアミド / RFアミド関連ペプチド / SNL / MANF / 小胞体ストレス / 再生 / 免疫 / ストレス / ２型糖尿病 / JNK / Toll様受容体4 / 5'-RACE / アストログリア / マクロファージ / リポ多糖(LPS) / ゴルジ体 / プロセシング / 翻訳後修飾 / 転写調節 / プロモーター / アストロサイト / ミクログリア / GDNF / 神経栄養因子 / 神経損傷の再生・修復 Less

加齢による小胞体プロテオスタシス変容の解析と老年病治療への応用Principal Investigator
- Principal Investigator
  
  大橋憲太郎
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gifu University
Analysis of the role of innate immune system in primary afferent neurons for the development of chronic pain mechanism
- Principal Investigator
  
  天谷文昌
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kyoto Prefectural University of Medicine
構造異常NOTCH3がO型糖鎖を介した調節で適切に除去される仕組みの解明
- Principal Investigator
  
  田嶌優子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nagoya University
ペルオキシソーム生合成におけるCD22/Siglec-2の役割の解明
- Principal Investigator
  
  高島茂雄
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Gifu University
メサンギウム細胞特異的Creマウスの創出による糸球体疾患進行機序の解明
- Principal Investigator
  
  内尾こずえ
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  National Institutes of Biomedical Innovation, Health and Nutrition
Interaction between GRK2 interactome and mitochondrial dysfunction for the development of chronic pain
- Principal Investigator
  
  Fumimasa Amaya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Mitochondrial inflammation and its mechanisms in the pathogenesis of chronic pain.
- Principal Investigator
  
  amaya fumimasa
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Exploration of ER-phagy substrates involved in brain aging and its application to the control of neuronal senescencePrincipal Investigator
- Principal Investigator
  
  Oh-hashi Kentaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 59:Sports sciences, physical education, health sciences, and related fields
- Research Institution
  Gifu University
Analysis of novel mechanisms of aging-related diseases focusing on Golgi stress signalingPrincipal Investigator
- Principal Investigator
  
  Oh-hashi Kentaro
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Gifu University
Novel pain control strategy focused on the Parkin and mitochondrial dysfunction.
- Principal Investigator
  
  Amaya Fumimasa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Analysis of arrestin and nociceptor coupling as a mechanism for the chronic pain development
- Principal Investigator
  
  Amaya Fumimasa
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Kyoto Prefectural University of Medicine
Exploring novel stress signaling pathways using a genome-editting approach for development of geriatric treatmentsPrincipal Investigator
- Principal Investigator
  
  Kentaro Oh-hashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  Gifu University
Stress responsive GADD34 and metabolic syndrome
- Principal Investigator
  
  isobe ken-ichi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya Women's University
Inflammasome mediated neuroinflammation as a novel target of chronic pain
- Principal Investigator
  
  Fumimasa Amaya
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Anesthesiology
- Research Institution
  Kyoto Prefectural University of Medicine
Therapeutic possibility of MANF, a new class of nerve growth factor, against neuropathic pain.
- Principal Investigator
  
  Amaya Fumimasa
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Anesthesiology
- Research Institution
  Kyoto Prefectural University of Medicine
Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCs
- Principal Investigator
  
  isobe ken-ichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya Women's University
  Nagoya University
Molecular characterization of a novel ER stress inducible factor, MANFPrincipal Investigator
- Principal Investigator
  
  OH-HASHI Kentaro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gifu University
Analysis of regulatory mechanisms of glial cell line-derived neurotrophic factorgene expression during nerve injury
- Principal Investigator
  
  KAZUTOSHI Kiuchi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Gifu University
神経細胞死抑制への新規GRP78結合タンパク質の関与と細胞内可視化Principal Investigator
- Principal Investigator
  
  大橋憲太郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Gifu University
左右非対称性決定におけるPKD‐inv経路の解明と生体内可視化Principal Investigator
- Principal Investigator
  
  大橋憲太郎
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  Gifu University
  Kyoto Prefectural University of Medicine
Involvement of inv-calmodulin pathway for left-right asymmetry formation
- Principal Investigator
  
  YOKOYAMA Takahiko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Developmental biology
- Research Institution
  Kyoto Prefectural University of Medicine
The functional morphology of Rfamide related peptide 1 (RFRP1) neuron
- Principal Investigator
  
  IBATA Yasuhiko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nerve anatomy/Neuropathology
- Research Institution
  Kyoto Prefectural University of Medicine
Search for new target genes regulated by neuron-restrictive silencer factor (NRSF)
- Principal Investigator
  
  NARUSE Yoshihisa
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neuroscience in general
- Research Institution
  Kyoto Prefectural University of Medicine

[Journal Article] Molecular characterization of the ER stress-inducible factor CRELD22024
- Author(s)
  Shohei Hinaga, Mahmoud Kandeel, Kentaro Oh-hashi
- Journal Title
  
  Cell Biochemistry Biophysics
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04030
[Journal Article] Regulation of the ER-Resident Mannosidase EDEM2 in HEK293 Cells2023
- Author(s)
  Murase Ryoichi、Kato Genki、Oh-hashi Kentaro
- Journal Title
  
  BPB Reports
  
  Volume: 6 Issue: 6 Pages: 193-199
- DOI
  10.1248/bpbreports.6.6_193
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04030
[Journal Article] Abnormal glomerular basement membrane maturation impairs mesangial cell differentiation during murine postnatal nephrogenesis2023
- Author(s)
  Uchio-Yamada Kozue、Yasuda Keiko、Oh-Hashi Kentaro、Manabe Noboru
- Journal Title
  
  American Journal of Physiology-Renal Physiology
  
  Volume: 324 Issue: 1 Pages: F124-F134
- DOI
  10.1152/ajprenal.00192.2022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04030
[Journal Article] Elucidation of OSW-1-Induced Stress Responses in Neuro2a Cells2023
- Author(s)
  Oh-hashi Kentaro、Nakamura Hibiki、Ogawa Hirotaka、Hirata Yoko、Sakurai Kaori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 6 Pages: 5787-5787
- DOI
  10.3390/ijms24065787
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21751, KAKENHI-PROJECT-22H04970, KAKENHI-PROJECT-19H04030
[Journal Article] Molecular characterization of wild-type and HSAN2B-linked FAM134B2023
- Author(s)
  Kanamori Akane、Hinaga Shohei、Hirata Yoko、Amaya Fumimasa、Oh-hashi Kentaro
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 7 Pages: 6005-6017
- DOI
  10.1007/s11033-023-08517-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21635, KAKENHI-PROJECT-19H04030, KAKENHI-PROJECT-21H03026
[Journal Article] Expression analysis and functional characterization of thioredoxin domain-containing protein 112022
- Author(s)
  Murase Ryoichi、Yamamoto Ayumi、Hirata Yoko、Oh-hashi Kentaro
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 49 Issue: 11 Pages: 10541-10556
- DOI
  10.1007/s11033-022-07932-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21751, KAKENHI-PROJECT-19H04030
[Journal Article] Hypomorphic mutation of PEX3 with peroxisomal mosaicism reveals the oscillating nature of peroxisome biogenesis coupled with differential metabolic activities2022
- Author(s)
  Takashima Shigeo、Fujita Haruka、Toyoshi Kayoko、Ohba Akiko、Hirata Yoko、Shimozawa Nobuyuki、Oh-hashi Kentaro
- Journal Title
  
  Molecular Genetics and Metabolism
  
  Volume: 137 Issue: 1-2 Pages: 68-80
- DOI
  10.1016/j.ymgme.2022.07.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03640, KAKENHI-PROJECT-20K08254, KAKENHI-PROJECT-19H04030
[Journal Article] Comparative Analysis of CREB3 and CREB3L2 Protein Expression in HEK293 Cells.2021
- Author(s)
  Oh-hashi K, Yamamoto A, Murase R, Hirata Y
- Journal Title
  
  Int J Mol Sci
  
  Volume: 22 Issue: 5 Pages: 2767-2767
- DOI
  10.3390/ijms22052767
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H04030, KAKENHI-PROJECT-20K21751
[Journal Article] Molecular characterization of mouse CREB3 regulatory factor in Neuro2a cells.2021
- Author(s)
  Oh-hashi K, Hasegawa T, Naruse Y, Hirata Y
- Journal Title
  
  Mol Biol Rep.
  
  Volume: 48 Issue: 7 Pages: 5411-5420
- DOI
  10.1007/s11033-021-06543-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H04030, KAKENHI-PROJECT-20K21751
[Journal Article] Characterization of IRE1α in Neuro2a cells by pharmacological and CRISPR/Cas9 approaches.2020
- Author(s)
  Oh-Hashi K, Kohno H, Kandeel M, Hirata Y
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 465(1-2) Issue: 1-2 Pages: 53-64
- DOI
  10.1007/s11010-019-03666-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19901, KAKENHI-PROJECT-19H04030
[Journal Article] Effects of 2-(2-Chlorophenyl)ethylbiguanide on ERAD Component Expression in HT-29 Cells Under a Serum- and Glucose-Deprived Condition2019
- Author(s)
  Oh-hashi Kentaro、Matsumoto Shiori、Sakai Takayuki、Hirata Yoko、Okuda Kensuke、Nagasawa Hideko
- Journal Title
  
  Applied Biochemistry and Biotechnology
  
  Volume: － Issue: 4 Pages: 1009-1021
- DOI
  10.1007/s12010-019-02969-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05102, KAKENHI-PROJECT-15K07894, KAKENHI-PROJECT-17K19901
[Journal Article] Elucidation of the Molecular Characteristics of Wild-Type and ALS-Linked Mutant SOD1 Using the NanoLuc Complementation Reporter System.2019
- Author(s)
  Oh-Hashi K, Hirata Y
- Journal Title
  
  Appl Biochem Biotechnol.
  
  Volume: 190(2) Issue: 2 Pages: 674-685
- DOI
  10.1007/s12010-019-03114-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19901, KAKENHI-PROJECT-19H04030
[Journal Article] Regulation of the ER-bound transcription factor Luman/CREB3 in HEK293 cells.2019
- Author(s)
  Oh-Hashi K, Takahashi K, Hirata Y.
- Journal Title
  
  FEBS Lett.
  
  Volume: 593(19) Issue: 19 Pages: 2771-2778
- DOI
  10.1002/1873-3468.13535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19901, KAKENHI-PROJECT-19H04030
[Journal Article] Functional validation of ATF4 and GADD34 in Neuro2a cells by CRISPR/Cas9-mediated genome editing.2018
- Author(s)
  Oh-hashi K, Sugiura N, Amaya F, Isobe KI, Hirata Y.
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 440 Issue: 1-2 Pages: 65-75
- DOI
  10.1007/s11010-017-3156-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19901, KAKENHI-PROJECT-15H04969, KAKENHI-PROJECT-26670692, KAKENHI-PROJECT-16H05280
[Journal Article] Elucidating post-translational regulation of mouse CREB3 in Neuro2a cells.2018
- Author(s)
  Oh-Hashi K, Soga A, Naruse Y, Takahashi K, Kiuchi K, Hirata Y.
- Journal Title
  
  Mol Cell Biochem.
  
  Volume: 448(1-2) Issue: 1-2 Pages: 287-297
- DOI
  10.1007/s11010-018-3333-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19901
[Journal Article] Application of NanoBiT for Monitoring Dimerization of the Null Hong Kong Variant of α-1-Antitrypsin, NHK, in Living Cells2018
- Author(s)
  Norisada Junpei、Fujimura Keito、Amaya Fumimasa、Kohno Hiroki、Hirata Yoko、Oh-hashi Kentaro
- Journal Title
  
  Molecular Biotechnology
  
  Volume: 60 Issue: 8 Pages: 539-549
- DOI
  10.1007/s12033-018-0092-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19704, KAKENHI-PROJECT-17K19901, KAKENHI-PROJECT-18H02899
[Journal Article] Expression analysis and functional characterization of the mouse cysteine-rich with EGF-like domains 2.2018
- Author(s)
  Oh-Hashi K, Fujimura K, Norisada J, Hirata Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 8(1) Issue: 1 Pages: 12236-12236
- DOI
  10.1038/s41598-018-30362-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19901
[Journal Article] Endoplasmic Reticulum Stress in the Dorsal Root Ganglion Contributes to the Development of Pain Hypersensitivity after Nerve Injury2018
- Author(s)
  Yamaguchi Yosuke、Oh-hashi Kentaro、Matsuoka Yutaka、Takemura Hitomi、Yamakita Shunsuke、Matsuda Megumi、Sawa Teiji、Amaya Fumimasa
- Journal Title
  
  Neuroscience
  
  Volume: 394 Pages: 288-299
- DOI
  10.1016/j.neuroscience.2018.08.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19704, KAKENHI-PROJECT-18H02899
[Journal Article] Acquired Exchange Protein Directly Activated by Cyclic Adenosine Monophosphate Activity Induced by p38 Mitogen-activated Protein Kinase in Primary Afferent Neurons Contributes to Sustaining Postincisional Nociception2017
- Author(s)
  Matsuda Megumi、Oh-hashi Kentaro、Yokota Isao、Sawa Teiji、Amaya Fumimasa
- Journal Title
  
  Anesthesiology
  
  Volume: 126 Issue: 1 Pages: 150-162
- DOI
  10.1097/aln.0000000000001401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04969, KAKENHI-PROJECT-26670692
[Journal Article] Application of a novel HiBiT peptide tag for monitoring ATF4 protein expression in Neuro2a cells.2017
- Author(s)
  Oh-hashi K, Furuta E, Fujimura K, Hirata Y.
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 12 Pages: 40-45
- DOI
  10.1016/j.bbrep.2017.08.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19901
[Journal Article] Application of NanoLuc to monitor the intrinsic promoter activity of GRP78 using the CRISPR/Cas9 system2016
- Author(s)
  Oh-Hashi K, Furuta E, Norisada J, Amaya F, Hirata Y, Kiuchi K.
- Journal Title
  
  Genes Cells
  
  Volume: 10 Issue: 10 Pages: 1137-1143
- DOI
  10.1111/gtc.12401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04969, KAKENHI-PROJECT-26670692
[Journal Article] A Comparative Analysis of the Molecular Features of MANF and CDNF2016
- Author(s)
  Norisada J, Hirata Y, Amaya F, Kiuchi K, Oh-Hashi K
- Journal Title
  
  PLoS One
  
  Volume: 11 Issue: 1 Pages: e0146923-e0146923
- DOI
  10.1371/journal.pone.0146923
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670692, KAKENHI-PROJECT-15H04969
[Journal Article] Role of an ER stress response element in regulating the bidirectional promoter of the mouse CRELD2-ALG12 gene pair.2010
- Author(s)
  Oh-hashi K, et al.
- Journal Title
  
  BMC Genomics.
  
  Volume: 11 Pages: 664-664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700403
[Journal Article] Role of an ER stress response element in regulating the bidirectional promoter of the mouse CRELD2-ALG12 gene pair.2010
- Author(s)
  Oh-hashi K, Koga H, Ikeda S, Shimada K, Hirata Y, Kiuchi K.
- Journal Title
  
  BMC Genomics. 11
  
  Pages: 664-664
- Data Source
  KAKENHI-PROJECT-21700403
[Journal Article] Biosynthesis, processing, and secretion of glial cell line-derived neurotrophic factor in astroglial cells.2009
- Author(s)
  Oh-hashi K., et al.
- Journal Title
  
  Molecular Cellular Biochemistry 323
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500320
[Journal Article] Biosynthesis, processing, and secretion of glial cell line-derived neurotrophic factor in astroglial cells2009
- Author(s)
  Oh-hashi K., Ito M., Tanaka T., Hirara Y. and Kiuchi K.
- Journal Title
  
  Mol. Cell. Biochem 323(1-2)
  
  Pages: 1-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500320
[Journal Article] CRELD2 is a novel endoplasmic reticulum stress-inducible gene2009
- Author(s)
  Oh-hashi K, et al., (他5名)
- Journal Title
  
  Biochem Biophys Res Commun 387
  
  Pages: 504-510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700403
[Journal Article] CRELD2 is a novel endoplasmic reticulum stress-inducible gene.2009
- Author(s)
  Oh-hashi K, Koga H, Ikeda S, Shimada K, Hirata Y, Kiuchi K.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 387(3)
  
  Pages: 504-510
- Data Source
  KAKENHI-PROJECT-21700403
[Journal Article] Identification of a novel GDNF mRNA induced by LPS in immune cell lines2008
- Author(s)
  Tanaka T. Oh-hashi K. Ito M, Shitara H, Hirata Y. and Kiuchi K.
- Journal Title
  
  Neurosci. Res. 61(1)
  
  Pages: 11-17
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500320
[Journal Article] NF-κB independent signaling pathway is responsible for LPS-induced GDNF gene expression in primary rat glial cultures2008
- Author(s)
  Tanaka T, Oh-hashi K, Shitara H, Hirata Y. and Kiuchi K
- Journal Title
  
  Neurosci. Lett 431(3)
  
  Pages: 262-267
- NAID
  120006341053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500320
[Journal Article] GRP78-binding protein regulates cAMP-induced glial fibrillary acidic protein expression in rat C6 glioblastoma cells.2006
- Author(s)
  Oh-hashi K et al.
- Journal Title
  
  FEBS lett. 580(16)
  
  Pages: 3943-3947
- NAID
  120006340376
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] Elevated neprilysin activity in vitreous of patients with proliferative diabetic retinopathy.2006
- Author(s)
  Hara H, Oh-hashi K et al.
- Journal Title
  
  Mol. Vis. 12
  
  Pages: 977-982
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] ER calcium discharge stimulates GDNF gene expression through MAPK-dependent and -independent pathways in rat C6 glioblastoma cells.2006
- Author(s)
  Oh-hashi K et al.
- Journal Title
  
  Neurosci. lett. 405(1-2)
  
  Pages: 100-105
- NAID
  120006340375
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] Rehmannia glutinosa induces glial cell line-derived neurotrophic factor gene expression in astroglial cells via cPKC and ERK1/2 pathways independently.2006
- Author(s)
  Yu H, Oh-hashi K et al.
- Journal Title
  
  Pharmacol Res. 54(1)
  
  Pages: 39-45
- NAID
  120006340374
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] p44/42 MAP kinase and c-Jun N-terminal kinase contribute to the up-regulation of caspase-3 in manganese-induced apoptosis in PC12 cells.2006
- Author(s)
  Ito Y, Oh-hashi K et al.
- Journal Title
  
  Brain Res. 1099 (1)
  
  Pages: 1-7
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] Determination of hypoxic effect on neprilysin activity in human neuroblastoma SH-SY5Y cells using novel HPLC methods.2005
- Author(s)
  Oh-hashi K et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 334(2)
  
  Pages: 380-385
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] Amyloid-beta peptides induce cell proliferation and macrophage colony-stimulating factor expression via PI3-kinase/Akt pathway in cultured Ra2 microglial cells.2005
- Author(s)
  Ito S, Sawada M, Haneda M, Fujii S, Oh-hashi K et al.
- Journal Title
  
  FEBS Lett. 579(9)
  
  Pages: 1995-2000
- Data Source
  KAKENHI-PROJECT-17790058
[Journal Article] Circadian and light-induced transcription of clock gene Perl depends on histone acetylation and deacetylation.2004
- Author(s)
  Naruse Y., Oh-hashi K, et al.
- Journal Title
  
  Mol.Cell Biol. 24(14)
  
  Pages: 6278-6287
- Data Source
  KAKENHI-PROJECT-15790109
[Journal Article] Hydrogen peroxide induces GADD153 in Jurkat cells through the protein kinase C-dependent pathway.2004
- Author(s)
  Oh-hashi K et al.
- Journal Title
  
  Redox Rep. 9(3)
  
  Pages: 173-178
- Data Source
  KAKENHI-PROJECT-15790109
[Presentation] Neuro2a細胞におけるOSW-1誘導性ストレス応答の解析2023
- Author(s)
  中村響、櫻井香里、大橋憲太郎
- Organizer
  日本薬学会東海支部合同学術大会
- Data Source
  KAKENHI-PROJECT-19H04030
[Presentation] ERファジー受容体FAM134Bの性状解析2023
- Author(s)
  金森朱音、大橋憲太郎
- Organizer
  日本薬学会東海支部合同学術大会
- Data Source
  KAKENHI-PROJECT-19H04030
[Presentation] HEK293細胞におけるER局在性転写因Luman/CREB3の調節2019
- Author(s)
  高橋貫人、平田洋子、大橋憲太郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K19901
[Presentation] HEK293細胞におけるER局在性転写因子Luman/CREB3の調節2019
- Author(s)
  高橋貫人 , 平田洋子 , 大橋憲太郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H04030
[Presentation] マウス cysteine-rich with EGF-like domains 2 の発現および機能の解析2018
- Author(s)
  藤村啓斗、平田洋子、大橋憲太郎
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K19901
[Presentation] Increased caspase1 activity in the DRG during inflammatory hyperalgesia2016
- Author(s)
  Y. MATSUOKA, K. OH-HASHI, F. AMAYA
- Organizer
  Society for Neuroscience Annual meeting 2016
- Place of Presentation
  米国サンディエゴ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26670692
[Presentation] Increased caspase1 activity in the DRG during inflammatory hyperalgesia2016
- Author(s)
  Y. MATSUOKA, K. OH-HASHI, F. AMAYA
- Organizer
  Society for Neuroscience annual meeting 2016
- Place of Presentation
  米国サンディエゴ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04969
[Presentation] 新規小胞体ストレス誘導遺伝子CRELD2の発現制御機構の解析2010
- Author(s)
  大橋憲太郎, et al.
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-21700403
[Presentation] 新規小胞体ストレス誘導遺伝子CRELD2の発現制御機構の解析2010
- Author(s)
  大橋憲太郎、平田洋子、木内一壽
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-21700403
[Presentation] 新規小胞体ストレス誘導因子CRELD2の細胞内挙動の解析2010
- Author(s)
  国枝亮佑、大橋憲太郎、平田洋子、木内一壽
- Organizer
  第33回日本分子生物学会・第83回日本生化学大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-21700403
[Presentation] グリア細胞株由来神経栄養因子(GDNF)遺伝子の発現誘導メカニズムの解析2008
- Author(s)
  田中達英、大橋憲太郎、松山幸弘、設楽裕信、平田洋子、木内一壽
- Organizer
  神経組織の成長・再生・移植研究会第23 回学術集会
- Place of Presentation
  千葉
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19500320
[Presentation] 初代培養グリア細胞におけるLPS誘導性GDNF遺伝子発現機構の解析2007
- Author(s)
  田中達英、大橋憲太郎、設楽裕信、平田洋子、木内一壽
- Organizer
  第30回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19500320
[Presentation] ラット初代培養グリア細胞における LPS 誘導性 GDNF 遺伝子発現機構の解析2007
- Author(s)
  設楽裕信、田中達英、大橋憲太郎、平田洋子、木内一壽
- Organizer
  第80 回日本生化学大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19500320
[Presentation] 初代培養グリア細胞における LPS 誘導性 GDNF 遺伝子発現機構の解析2007
- Author(s)
  田中達英、大橋憲太郎、設楽裕信、平田洋子、木内一壽
- Organizer
  第 30 回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19500320
[Presentation] ラット初代培養グリア細胞におけるLPS誘導性GDNF遺伝子発現機構の解析2007
- Author(s)
  設楽裕信、田中達英、大橋憲太郎、平田洋子、木内一壽
- Organizer
  第80回日本生化学大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-14
- Data Source
  KAKENHI-PROJECT-19500320

1. Amaya Fumimasa (60347466)

# of Collaborated Projects: 10 results

# of Collaborated Products: 10 results
2. 中川貴之 (30303845)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. IIJIMA Norio (00285248)

# of Collaborated Projects: 3 results

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4. NARUSE Yoshihisa (00326216)

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5. 内尾こずえ (70373397)

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6. isobe ken-ichi (20151441)

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7. 西尾尚美 (80513457)

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8. 長谷川忠男 (10314014)

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9. 佐和貞治 (10206013)

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10. 石垣診祐 (40378170)

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11. 高島茂雄 (50537610)

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12. KAZUTOSHI Kiuchi (30135339)

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# of Collaborated Products: 8 results
13. IBATA Yasuhiko (10079684)

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14. TANAKA Masaki (80264753)

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15. YOKOYAMA Takahiko (70191525)

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16. SUGIYAMA Noriyuki (90381954)

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17. SHIBA Dai (50360722)

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18. 祖父江元 (20148315)

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19. 伊藤佐知子 (70447845)

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20. 岡林志帆子 (00744898)

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21. 澤田麻衣子 (90330860)

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23. 藤本豊士 (50115929)

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24. 山北俊介 (10836092)

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25. 堀井靖彦 (90882720)

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26. 田嶌優子 (10423104)

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27. 安田圭子 (00836265)

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28. 永沢秀子

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29. 下澤伸行

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OHASHI Kentaro 大橋 憲太郎

Kentaro Oh-hashi 大橋 憲太郎

OH-HASHI Kentaro 大橋 憲太郎

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加齢による小胞体プロテオスタシス変容の解析と老年病治療への応用Principal Investigator

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Exploration of ER-phagy substrates involved in brain aging and its application to the control of neuronal senescencePrincipal Investigator

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Analysis of novel mechanisms of aging-related diseases focusing on Golgi stress signalingPrincipal Investigator

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Exploring novel stress signaling pathways using a genome-editting approach for development of geriatric treatmentsPrincipal Investigator

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OHASHI Kentaro 大橋憲太郎

Kentaro Oh-hashi 大橋憲太郎

OH-HASHI Kentaro 大橋憲太郎