KUBO Hajime 久保肇

Researcher Number	50362520
Affiliation (based on the past Project Information) *help	2010: 京都大学, 医学研究所, 講師 2007 – 2010: Kyoto University, Department of Surgery, Associate Professor 2005 – 2006: Kyoto University, Graduate School of Medicine, Associate Professor, 医学研究科, 科学技術振興助教授 2004: 京都大学, 医学研究科, 研究員(科学技術振興)(常勤形態)
Review Section/Research Field	Principal Investigator General surgery / Biological Sciences / Digestive surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator RNA編集 / リンパ節転移 / リンパ管新生 / ES細胞 / 癌抑制遺伝子 / Prox1 / 癌 / 癌幹細胞 / 大腸癌 / がん幹細胞 … More / 転移 / 血管新生 / RNA mutation / homebox gene / oncogene / ゲノム / RNA / RNA変異 / 転写因子 / 癌遺伝子 / RNA editing / tumor suppressor gene / ES cells / Lymph node metastasis / Lymphangiogensis / がん抑制遺伝子 / 創薬 / 分子標的 / 分子標的治療 / がん間質細胞 / リンパ管 … More Except Principal Investigator 発癌 / 抗体療法 / 大腸癌肝転移 / 大腸癌発生 / WNT伝達系 / FZD10 / Wnt伝達系 / 浸潤 / 大腸癌 Less

Targeting therapy against cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  KUBO Hajime
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
A role of FZD10, a WNT receptor, in the colon carcinogenesis.
- Principal Investigator
  
  NAGAYAMA Satoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Anovel mechanism of tumor progression by the candidate tumor suppressor Proxl : RNA mutation in cancerPrincipal Investigator
- Principal Investigator
  
  KUBO Hajime
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Lymphangiogenesis in cancerPrincipal Investigator
- Principal Investigator
  
  KUBO Hajime
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
リンパ管形成の分子機構解明とがんリンパ節転移の制御Principal Investigator
- Principal Investigator
  
  久保肇
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Research for molecular mechanisms of lymphangiogenesis and lymph node metastasisPrincipal Investigator
- Principal Investigator
  
  KUBO Hajime
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University

All 2011 2010 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Transcriptional Factor Prox1 Plays an Essential Role in the Antiproliferative Action of Interferon-γ in Esophageal Cancer Cells.2011
- Author(s)
  Akagami M, Kawada K, Kubo H, Kawada M, Takahashi M, Kaganoi J, Kato S, Itami A, Shimada Y, Watanabe G, Sakai Y.
- Journal Title
  
  Ann Surg Oncol. 31 [Epub ahead of print]
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] The importance of precompression time for secure stapling with a linear stapler.2010
- Author(s)
  Nakayama S, Hasegawa S, Nagayama S, Kato S, Hida K, Tanaka E, Itami A, Kubo H, Sakai Y.
- Journal Title
  
  Surg Endosc. 24 [Epub ahead of print]
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis.2009
- Author(s)
  Matsusue R, Kubo H, Hisamori S, Okoshi K, Takagi H, Hida K, Nakano K, Itami A, Kawada K, Nagayama S, Sakai Y.
- Journal Title
  
  Ann Surg Oncol.2009 Sep 16(9)
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2009
- Author(s)
  Nagayama S, Yamada E, Kohno Y, Aoyama T, Fukukawa C, Kubo H, Watanabe G, Katagiri T, Nakamura Y, Sakai Y, Toguchida J
- Journal Title
  
  Cancer Sci 100
  
  Pages: 405-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591589
[Journal Article] Hepatic Stellate Cells Promote Liver Metastasis of Colon Cancer Cells by the Action of SDF-1/CXCR4 Axis.2009
- Author(s)
  Matsusue R, * Kubo H, Hisamori S, Okoshi K, Takagi H, Hida K, Nakano K, Itami A, Kawada K, Nagayama S, Sakai Y.
- Journal Title
  
  Ann Surg Oncol. 16(9)
  
  Pages: 2645-53
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production.2008
- Author(s)
  Hisamori S, Tabata C, Kadokawa Y, Okoshi K, Tabata R, Mori A, Nagayama S Watanabe G, Kubo H, Sakai Y.
- Journal Title
  
  Liver Int. 2008 28(9)
  
  Pages: 1217-1225
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] All-trans-retinoic acid attenuates radiation-induced intestinal fibrosis in mice.2008
- Author(s)
  Kae Okoshi, Hajime Kubo, et al.
- Journal Title
  
  J Surg Res. 150
  
  Pages: 53-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2008
- Author(s)
  Nagayama S, Yamada E, Kohno Y, Aoyama T, Fukukawa C, Kubo H, Watanabe G, Katagiri T, Nakamura Y, Sakai Y, Toguchida J.
- Journal Title
  
  Cancer Sci. 2009 Mar 100(3)
  
  Pages: 405-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2008
- Author(s)
  Nagayama S, Yamada E, Kohno Y, Aoyama T, Fukukawa C, Kubo H, Watanabe G, Katagiri T, Nakamura Y, Sakai Y, Toguchida J.
- Journal Title
  
  Cancer Sci.2009 100(3)
  
  Pages: 402-412
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine2008
- Author(s)
  Shigeo Hisamori, Hajime Kubo, et al.
- Journal Title
  
  Liver Int. 28
  
  Pages: 1217-1225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] All-trans-retinoic acid attenuates radiation-induced intestinal fibrosis in mice.2008
- Author(s)
  Kae Okoshi, * Hajime Kubo, Satoshi Nagayama, Chiharu Tabata, Yoshio Kadokawa, Shigeo Hisamori, Yoshikuni Yonenaga, Akihisa Fujimoto, Akira Mori, Hisashi Onodera, Go Watanabe, Yoshiharu Sakai
- Journal Title
  
  J Surg Res. 150
  
  Pages: 53-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans-retinoic acid attenuates radiation-induced intestinal fibrosis in mice2008
- Author(s)
  Kae Okoshi, Hajime Kubo, et.al.
- Journal Title
  
  J Surg Res 150
  
  Pages: 53-59
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production2008
- Author(s)
  Shigeo Hisamori, Hajime Kubo, et.al.
- Journal Title
  
  Liver Int 28
  
  Pages: 1217-1225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production.2008
- Author(s)
  Shigeo Hisamori, Chiharu Tabata, Yoshio Kadokawa, Kae Okoshi, Rie Tabata, Akira Mori, Satoshi Nagayama, Go Watanabe, * Hajime Kubo, Yoshiharu Sakai
- Journal Title
  
  Liver Int. 28
  
  Pages: 1217-1225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans-retinoic acid attenuates radiation-induced intestinal fibrosis in mice.2008
- Author(s)
  Okoshi K, Kubo H, Nagayama S, Tabata C, Kadokawa Y, Hisamori S, Yonenaga Y, Fujimoto A, Mori A, Onodera H, Watanabe G, Sakai Y.
- Journal Title
  
  J Surg Res. 2008 150(1)
  
  Pages: 53-59
- Data Source
  KAKENHI-PROJECT-20390341
[Journal Article] Two populations OF Thyl-positive mesenchymal cells regulate the in vitro maturation of hepatic progenitor cells.2007
- Author(s)
  Kamo N, Yasuchika K. Ishii T, Fujita N, Tsuruo T, Yamashita JK, Kubo H, Ikai I
- Journal Title
  
  Am J Physiol Gastr Liver Physiol. 292
  
  Pages: 526-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Two populations of Thyl-positive mesenchymal cells regulate the in vitro maturation of hepatic progenitor cells.2007
- Author(s)
  Kamo N, Yasuchika K, Fujii H, Hoppo T, Machimoto T, Ishii T, Fujita N, Tsuruo T, Yamashita JK, Kubo H, Ikai I
- Journal Title
  
  Am J Physiol Gastr Liver Physiol. 292
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] RNA mutations of proxl detected in human esophageal cancer cells by the shifted termination assay.2007
- Author(s)
  Yoshimoto T, Takahashi M, Nagayama S, Watanabe G, Shimada Y, Sakai Y, Kubo H
- Journal Title
  
  BBRC 359
  
  Pages: 258-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] Two populations of Thyl-positive mesenchymal cells regulate the in vitro maturation of hepatic progenitor cells.2007
- Author(s)
  Kamo N, Yasuchika K, Fujii H, Hoppo T, Machimoto T, Ishii T, Fujita N, Tsuruo T, Yamashita JK, Kubo H, Ikai I
- Journal Title
  
  Am J Physiol Gastr Liver Physiol. 292
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Prox1 Induces Lymphatic Endothelial Differentiation via Integrin {alpha}9 and Other Signaling Cascades.2007
- Author(s)
  Mishima K, Watabe T, Saito A, Yoshimatsu Y, Imaizumi N, Masui S, Hirashima M, Morisada T, Oike Y, Araie M, Niwa H, Kubo H, Suda T, Miyazono K
- Journal Title
  
  Mol Biol Cell. 18(4)
  
  Pages: 1421-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Two populations of Thy1-positive mesenchymal cells regulate the in vitro maturation of hepatic progenitor cells.2007
- Author(s)
  Kamo N, Yasuchika K, Fujii H, Hoppo T, Machimoto T, Ishii T, Fujita N, Tsuruo T, Yamashita JK, *Kubo H, Ikai I
- Journal Title
  
  Am J Physiol Gastr Liver Physiol. 292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] RNA mutations of prox1 detected in human esophageal cancer cells by the shifted termination assay.2007
- Author(s)
  Yoshimoto T, Takahashi M, Nagayama S, Watanabe G, Shimada Y, Sakai Y, * Kubo H
- Journal Title
  
  BBRC 359(2)
  
  Pages: 258-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Immunohistochemical detection of the lymphatic marker podoplanin in diverse types of human cancer cells using a novel antibody.2007
- Author(s)
  Kono T, Shimoda M, Takahashi M, Matsumoto K, Yoshimoto T, Mizutani M, Tabata C, Okoshi K, Wada H, *Kubo H
- Journal Title
  
  Int J Oncol. 31(3)
  
  Pages: 501-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice.2007
- Author(s)
  Tabata C, Tabata R, Kadokawa Y, Hisamori S, Takahashi M, Mishima M, Nakano T, Kubo H
- Journal Title
  
  J Immunol. 179
  
  Pages: 208-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice.2007
- Author(s)
  Tabata C, Tabata R, Kadokawa Y, Hisamori S, Takahashi M, Mishima M, Nakano T, Kubo H
- Journal Title
  
  J Immunol. 179(1)
  
  Pages: 708-14
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Thalidomide prevents bleomycin-induced pulmonary fibrosis in mice.2007
- Author(s)
  Tabata C, Tabata R, Kadokawa Y, Hisamori S, Takahashi M, Mishima M, Nakano T, Kubo H
- Journal Title
  
  J Immunol. 179
  
  Pages: 208-214
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] The Perivascular space as a path of Hematopoietic progenitor cells and Mature T cells between the blood circulation and the Thymic parenchyma.2007
- Author(s)
  Mori M, Itoi M, Taukamoto N, Kubo H, Amagai T
- Journal Title
  
  Int Immunol. 19(6)
  
  Pages: 745-53
- NAID
  10020109678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Two populations of Thyl-positive mesenchymal cells regulate the in vitro maturation of hepaticprogenitor cells.2007
- Author(s)
  Kamo N, Yasuchika K, Ishii T, Fujita N, Tsuruo T, Yamashita JK, Kubo H, Ikai I
- Journal Title
  
  Am J Physiol Gastr Liver Physiol. 292
  
  Pages: 526-534
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] RNA mutations of proxl detected in human esophageal cancer cells by the shifted termination assay.2007
- Author(s)
  Yoshimoto T, Takahashi M, Nagayama S, Watanabe G, Shimada Y, Sakai Y, Kubo H
- Journal Title
  
  BBRC 359
  
  Pages: 258-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] A homeobox protein prox1 is involved in the differentiation, proliferation and prognosis in hepatocellular carcinoma.2006
- Author(s)
  Shimoda M, Takahashi M, Yoshimoto T, Kono T, Ikai I, *Kubo H
- Journal Title
  
  Clin Cancer Res. 12
  
  Pages: 6005-11
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans retinoic acid modulates proliferation of lung fibroblasts via IL-6/IL-6R system.2006
- Author(s)
  Tabata C., Kubo H., Tabata R., Wada M., Sakuma K., Ichikawa M., Fujita S., Mio T, Mishima M
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol. 290
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] All-trans retinoic acid modulates proliferation of lung fibroblasts via IL-6/IL-6R system.2006
- Author(s)
  Chiharu Tabata, Hajime Kubo, Rie Tabata, Manabu Wada, Keiichiro Sakuma, Masataka Ichikawa, Shiro Fujita, Tadashi Mio, Michiaki Mishima
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol 290
- Data Source
  KAKENHI-PROJECT-16390378
[Journal Article] All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis.2006
- Author(s)
  Tabata C, Kadokawa Y, Tabata R, Takahashi M, Okoshi K, Sakai Y, Mishima M, Kubo H
- Journal Title
  
  Am J Respir Crit Care Med. 174
  
  Pages: 1352-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Differentiation of lymphatic endothelial cells from Embryonic Stem cells on OP9 stromal cells.2006
- Author(s)
  Kono T, *Kubo H (equally first author), Shimazu C, Ueda Y, Takahashi M, Yanagi K, Fujita N, Tsuruo T, Wada H, Yamashita JK
- Journal Title
  
  Arterioscler Thromb Vasc Biol. 26
  
  Pages: 2070-2076
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans retinoic acid modulates proliferation of lung fibroblasts via IL-6/IL-6R system.2006
- Author(s)
  Tabata C, Kubo H, Tabata R, Wada M, Sakuma K, Ichikawa M, Fujita S, Mio T, Mishima M
- Journal Title
  
  Am J Physiol Lung Cell Mol Physiol. 290
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] A homeobox protein proxl is involved in the differentiation, proliferation and prognosis in hepatocellular carcinoma2006
- Author(s)
  Shimoda, M., Takahashi, M., Yoshimoto, T., Kono, T., Ikai, I., Kubo, H
- Journal Title
  
  Clin Can Res 12(20)
  
  Pages: 6005-6011
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] All-trans-retinoic acid prevents radiation- or bleomycin-induced pulmonary fibrosis.2006
- Author(s)
  Tabata C, Kadokawa Y, Tabata R, Takahashi M, Okoshi K, Sakai Y, Mishima M, Kubo H
- Journal Title
  
  Am J Respir Crit Care Med. 174
  
  Pages: 1352-1360
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] Differentiation of lymphatic endothelial cells from Embryonic Stem cells on OP9 stromal cells.2006
- Author(s)
  Kono, T., Kubo, H., Shimazu, C., Ueda Y., Takahashi, M., Yanagi, K., Fujita, N., Tsuruo.T., Wada, H., Yamashita, JK
- Journal Title
  
  Arterioscler Thromb Vasc Biol 26(9)
  
  Pages: 2070-2076
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Loss of function of the candidate tumor suppressor prox1 by RNA mutation in human cancer cells.2006
- Author(s)
  Takahashi M, Yoshimoto T, Shimoda M, Kono T, Koizumi M, Yazumi S, Shimada Y, Doi R, Chiba T, *Kubo H
- Journal Title
  
  Neoplasia 8
  
  Pages: 1003-1010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] A homeobox protein proxl is involved in the differentiation, proliferation and prognosis in hepatocellular carcinoma2006
- Author(s)
  Shimoda, M., Takahashi, M., Yoshimoto, T., Kono, T, Ikai, I., Kubo, H
- Journal Title
  
  Clin Can Res 12(20)
  
  Pages: 6005-6011
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Loss of function of the candidate tumor suppressor proxl by RNA mutation in human cancer cells.2006
- Author(s)
  Takahashi, M., Yoshimoto.T., Shimoda.M., Kono.T., Koisumi, M., Yazumi, S., Shimada, Y., Doi, R., Chiba.T., Kubo, H
- Journal Title
  
  Neoplasia 8(12)
  
  Pages: 1003-1010
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] Loss of function of the candidate tumor suppressor proxl by RNA mutation in human cancer cells.2006
- Author(s)
  Takahashi, M., Yoshimoto, T., Shimoda, M., Kono, T., Koisumi, M., Yazumi, S., Shimada, Y., Doi, R., Chiba, T., Kubo.H
- Journal Title
  
  Neoplasia 8(12)
  
  Pages: 1003-1010
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] All-trans retinoic acid modulates proliferation of lung fibroblasts via IL-6/IL-6R system.2006
- Author(s)
  Chiharu Tabata, Hajime Kubo, Rie Tabata, Manabu Wada Keiichiro Sakuma Masataka Ichikawa Shiro Fujita, Tadashi Mio, Michiaki Mishima
- Journal Title
  
  Am J Physiol Lung cell Mol Physiol 290
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Differentiation of lymphatic endothelial cells from Embryonic Stem cells on OP9 stromal cells.2006
- Author(s)
  Kono, T., Kubo.H., Shimazu, C., Ueda Y., Takahashi, M., Yanagi, K., Fujita.N., Tsuruo.T., Wada.H., Yamashita.JK
- Journal Title
  
  Arterioscler Thromb Vasc Biol Sep;26(9)
  
  Pages: 2070-2076
- Data Source
  KAKENHI-PROJECT-18390345
[Journal Article] Vascular endothelial growth factor-D is dispensable for development of the lymphatic system.2005
- Author(s)
  Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 2441-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Vascular endothelial growth factor-D is dispensable for development of the lymphatic system.2005
- Author(s)
  Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 2441-2449
- Data Source
  KAKENHI-PROJECT-16022238
[Journal Article] Lymphangiogenesis-Mediated Shedding of LAM Cell Clusters as a Mechanism for Dissemination in Lymphangioleiomyomatosis.2005
- Author(s)
  Kumasaka T, Seyama K, Mitani K, Souma S, Kashiwagi S, Hebisawa A, Sato T, Kubo H, Gomi K, Shibuya K, Fukuchi Y, Suda K
- Journal Title
  
  Am J Surg Pathol. 29
  
  Pages: 1356-1366
- Data Source
  KAKENHI-PROJECT-16390378
[Journal Article] Vascular endothelial growth factor-D is dispensable for development of the lymphatic system.2005
- Author(s)
  Baldwin ME, Halford MM, Roufail S, Williams RA, Hibbs ML, Grail D, Kubo H, Stacker SA, Achen MG
- Journal Title
  
  Mol Cell Biol. 25
  
  Pages: 2441-2449
- Data Source
  KAKENHI-PROJECT-16390378
[Journal Article] Lymphangiogenesis-Mediated Shedding of LAM Cell Clusters as a Mechanism for Dissemination in Lymphangioleiomyomatosis.2005
- Author(s)
  Kumasaka T, Seyama K Mitani K, Souma S Kashiwagi S, Hebisawa A, Sato T, Kubo H Gomi K, Shibuya K, Fukuchi Y, Suda K
- Journal Title
  
  Am Surg Pathol. 29
  
  Pages: 1356-1366
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Lymphangiogenesis-Mediated Shedding of LAM Cell Clusters as a Mechanism for Dissemination in Lymphangioleiomyomatosis.2005
- Author(s)
  Kumasaka T, Seyama K, Mitani K, Souma S, Kashiwagi S, Hebisawa A, Sato T, Kubo H, Gomi K, Shibuya K, Fukuchi Y, Suda K
- Journal Title
  
  Am J Surg Pathol. 29
  
  Pages: 1356-1366
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014047
[Journal Article] Molecular mechanisms of lymphangiogenesis in diseases.2004
- Author(s)
  Kubo H, Kono T
- Journal Title
  
  Microcirculation annual. 20
  
  Pages: 3-4
- Data Source
  KAKENHI-PROJECT-16390378
[Journal Article] Molecular mechanisms of lymphangiogenesis.2004
- Author(s)
  Takahashi M, Yoshimoto T, Kubo H.
- Journal Title
  
  Int J Hematol. 80・1
  
  Pages: 29-34
- NAID
  10013333909
- Data Source
  KAKENHI-PROJECT-16390378
[Journal Article] Molecular mechanisms of lymphangiogenesis in diseases.2004
- Author(s)
  Kubo H., Kono T
- Journal Title
  
  Microcirculation annual. 20
  
  Pages: 3-4
- Data Source
  KAKENHI-PROJECT-16022238
[Journal Article] Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer.2004
- Author(s)
  Shimizu K, Kubo H, Yamaguchi K, Kawashima K, Ueda Y, Matsuo K, Awane M, Shimahara Y, Takabayashi A, Yamaoka Y, Satoh S.
- Journal Title
  
  Cancer Sci. 95
  
  Pages: 328-333
- NAID
  10013722475
- Data Source
  KAKENHI-PROJECT-16390378
[Journal Article] Molecular mechanisms of lymphangiogenesis.2004
- Author(s)
  Takahashi M, Yoshimoto T, Kubo H.
- Journal Title
  
  Int J Hematol. 80・1
  
  Pages: 29-34
- NAID
  10013333909
- Data Source
  KAKENHI-PROJECT-16022238
[Journal Article] Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer2004
- Author(s)
  Shimizu K, Kubo H, Yamaguchi K, Kawashima K, Ueda Y, Matsuo K, Awane M, Shimahara Y, Takabayashi A, Yamaoka Y, Satoh S.
- Journal Title
  
  Cancer Sci. 95
  
  Pages: 328-333
- NAID
  10013722475
- Data Source
  KAKENHI-PROJECT-16022238
[Presentation] 大腸がんの肝転移における星細胞による誘導がん幹細胞(iCSC)の役割2009
- Author(s)
  久保肇
- Organizer
  第18回がん転移学会学術集会、シンポジウム
- Place of Presentation
  旭川
- Year and Date
  2009-07-23
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] 消化器癌転移の新しい分子機構と新規治療法:リンパ管新生および癌幹細胞の研究2007
- Author(s)
  久保肇
- Organizer
  第62回日本消化器外科学会総会、シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] Lymphangiogenesis and cancer2006
- Author(s)
  Kubo, H.
- Organizer
  The 11th International Congress of Metastasis Research Society, Plenary Sessions
- Place of Presentation
  Tokushima
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管新生と癌2006
- Author(s)
  久保肇
- Organizer
  第2回Summer Vascular Conference
- Place of Presentation
  軽井沢
- Year and Date
  2006-09-02
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管新生とがん転移2006
- Author(s)
  久保肇
- Organizer
  第30回日本リンパ学会
- Place of Presentation
  東京
- Year and Date
  2006-06-01
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390345
[Presentation] Lymphangiogenesis and cancer2006
- Author(s)
  Hajime, Kubo
- Organizer
  Lymphology meeting
- Place of Presentation
  Tokyo
- Year and Date
  2006-06-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390345
[Presentation] リンパ管新生とがん転移2006
- Author(s)
  久保肇
- Organizer
  第30回日本リンパ学会、シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管新生の分子機構とがんリンパ節転移2006
- Author(s)
  久保肇
- Organizer
  第8回Sentinel Node Navigation Surgery研究会学術集会、サテライトシンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] ヒト癌細胞におけるホメオボックス遺伝子のRNA編集2005
- Author(s)
  高橋めい子、吉本貴宣、久保肇
- Organizer
  第64回日本癌学会、ポスター
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管新生の分子機構の解明とがんリンパ節転移制御2005
- Author(s)
  久保肇
- Organizer
  第78回日本薬理学会年会、シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] がんとリンパ管;そしてリンパ管関連分子とがんについて2005
- Author(s)
  久保肇
- Organizer
  第1回先端がん転移研究交流会
- Place of Presentation
  鳴門
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] Differentiation of Lymphatic endothelial cells from ES cells2005
- Author(s)
  河野朋哉、久保肇
- Organizer
  AIM meeting, ポスター
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管新生の分子機構とがんリンパ節転移2005
- Author(s)
  久保肇
- Organizer
  第64回日本癌学会、シンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管内皮細胞分化にかかわる分子2005
- Author(s)
  久保肇
- Organizer
  第29回日本リンパ学会、シンポジウム
- Place of Presentation
  宇部
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] Recent progress in lymphangiogenesis research2005
- Author(s)
  Kubo, H.
- Organizer
  Korea-Japan Joint Symposium Vascular Biology, Symposium
- Place of Presentation
  Chuncheon
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] Lymphangiogenesis and cancer2005
- Author(s)
  Kubo, H.
- Organizer
  International Symposium on Tumor Biology in Kanazawa, Symposium
- Place of Presentation
  Kanazawa
- Year and Date
  2005-01-20
- Data Source
  KAKENHI-PROJECT-17014047
[Presentation] リンパ管新生研究の新しい知見2005
- Author(s)
  久保肇
- Organizer
  第28回日本分子生物学会、シンポジウム
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-17014047

1. OBMA Kazutaka (50322649)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. NAGAYAMA Satoshi (70362499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SAKAI Yoshiharu (60273455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. TOGUCHIDA Junya (40273502)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 戸田口淳也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUBO Hajime 久保 肇

Research Projects

Research Products

Co-Researchers

Targeting therapy against cancer stem cellsPrincipal Investigator

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A role of FZD10, a WNT receptor, in the colon carcinogenesis.

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Anovel mechanism of tumor progression by the candidate tumor suppressor Proxl : RNA mutation in cancerPrincipal Investigator

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Lymphangiogenesis in cancerPrincipal Investigator

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リンパ管形成の分子機構解明とがんリンパ節転移の制御Principal Investigator

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Research for molecular mechanisms of lymphangiogenesis and lymph node metastasisPrincipal Investigator

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[Journal Article] Transcriptional Factor Prox1 Plays an Essential Role in the Antiproliferative Action of Interferon-γ in Esophageal Cancer Cells.2011

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[Journal Article] The importance of precompression time for secure stapling with a linear stapler.2010

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[Journal Article] Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis.2009

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[Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2009

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[Journal Article] Hepatic Stellate Cells Promote Liver Metastasis of Colon Cancer Cells by the Action of SDF-1/CXCR4 Axis.2009

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[Journal Article] All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine production.2008

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[Journal Article] All-trans-retinoic acid attenuates radiation-induced intestinal fibrosis in mice.2008

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[Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2008

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[Journal Article] Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.2008

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[Journal Article] All-trans-retinoic acid ameliorates carbon tetrachloride-induced liver fibrosis in mice through modulating cytokine2008

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KUBO Hajime 久保肇