Karasaki Hidenori 唐崎秀則

Researcher Number	50374806
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2022: 医療法人徳洲会札幌東徳洲会病院医学研究所, がん生物研究部, 客員研究員 2020 – 2022: 医療法人徳洲会札幌東徳洲会病院医学研究所, 外科的消化器病疾患研究部, 客員研究員 2017 – 2019: 医療法人徳洲会札幌東徳洲会病院医学研究所, 外科的消化器病疾患研究部, 副部門長
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 55020:Digestive surgery-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Gastroenterology
Keywords	Principal Investigator Clonarity / 膵癌 / 膵発癌素地 / 液体生検 / heterogeneity / field defect / 低異型度病変 / 指標病変 / KRAS / 領域発癌 … More / 膵発癌 / 正常膵管 / clonality / 膵管内病変 / 背景膵 … More Except Principal Investigator IPMN / 膵癌 / クローン進化 / 膵管内乳頭粘液性腫瘍 / 発癌素地 / 多領域シーケンシング / 早期診断 / 多領域シーケンス / 分子サブタイプ / 分子機構 / 浸潤 / Visium空間トランスクリプトーム解析 / ゲノムプロファイリング / 病理マッピング / 早期発見 / 癌バイオマーカー / バイオマーカー / 遊離核酸 / がん早期発見 / デジタルPCR / 遊離RNA / ドライバー変異 / リキッドバイオプシー / 細胞 / 初代細胞 / GNAS Less

Study for novel biomarker in liquid biopsy on on carcinogenic pathways induced by driver mutations
- Principal Investigator
  
  Ono Yusuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
Elucidation of the molecular mechanisms responsible for IPMNs progression
- Principal Investigator
  
  IMAI KOJI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Asahikawa Medical College
Distribution and clonality of multiple intraductal neoplasms of the pancreas evaluated by morphologyPrincipal Investigator
- Principal Investigator
  
  Karasaki Hidenori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Center for Clinical and Biomedical Research, Sapporo Higashi Tokushukai Hospital
Early diagnosis of pancreatic cancer based on diversity of field defect and molecular genetic approach
- Principal Investigator
  
  Mizukami Yusuke
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
Diversity of molecular paths during pancreatic carcinogenesis
- Principal Investigator
  
  Mizukami Yusuke
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Multiplex Digital PCR Assay to Detect Multiple KRAS and GNAS Mutations Associated with Pancreatic Carcinogenesis from Minimal Specimen Amounts2023
- Author(s)
  Maeda Chiho、Ono Yusuke、Hayashi Akihiro、Takahashi Kenji、Taniue Kenzui、Kakisaka Rika、Mori Miyuki、Ishii Takahiro、Sato Hiroki、Okada Tetsuhiro、Kawabata Hidemasa、Goto Takuma、Tamamura Nobue、Omori Yuko、Takahashi Kuniyuki、Katanuma Akio、Karasaki Hidenori、Liss Andrew Scott、Mizukami Yusuke
- Journal Title
  
  The Journal of Molecular Diagnostics
  
  Volume: 23 Issue: 6 Pages: 1525-1578
- DOI
  10.1016/j.jmoldx.2023.02.007
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07954, KAKENHI-PROJECT-21KK0283, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-21K20855, KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-23K06759, KAKENHI-PROJECT-22K16010, KAKENHI-PROJECT-21H02758
[Journal Article] Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway2022
- Author(s)
  Kawabata Hidemasa、Ono Yusuke、Tamamura Nobue、Oyama Kyohei、Ueda Jun、Sato Hiroki、Takahashi Kenji、Taniue Kenzui、Okada Tetsuhiro、Fujibayashi Syugo、Hayashi Akihiro、ほか
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 57 Issue: 3 Pages: 208-220
- DOI
  10.1007/s00535-021-01846-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16947, KAKENHI-PUBLICLY-20H04896, KAKENHI-PROJECT-19K07261, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K07954, KAKENHI-PROJECT-20K17009, KAKENHI-PROJECT-21KK0283, KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-19K06452, KAKENHI-PROJECT-21H02758
[Journal Article] Predictors of Long-Term Survival in Pancreatic Ductal Adenocarcinoma after Pancreatectomy: TP53 and SMAD4 Mutation Scoring in Combination with CA19-92022
- Author(s)
  Ono M, Ono Y, Nakamura T, Tsuchikawa T, Kuraya T, Kuwabara S, Nakanishi Y, Asano T, Matsui A, Tanaka K, Ebihara Y, Kurashima Y, Noji T, Murakami S, Shichinohe T, Mitsuhashi T, Omori Y, Furukawa T, Taniue K, Suzuki M, Sugitani A, Karasaki H, Mizukami Y, Hirano S.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 29 Issue: 8 Pages: 5007-5019
- DOI
  10.1245/s10434-022-11630-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-21H02758
[Journal Article] Distinct effects of TU-100 (daikenchuto) on long-lasting dysbiosis in the small intestine in patients with colorectal cancer and inflammatory bowel disease2022
- Author(s)
  Kono T, Maejima T, Ono Y, Ito T, Furukawa S, Nishiyama M, Yamamoto M, Sugitani A, Karasaki H, Mizukami Y, Maemoto A.
- Journal Title
  
  Gene
  
  Volume: 820 Pages: 146266-146266
- DOI
  10.1016/j.gene.2022.146266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070
[Journal Article] ゲノム解析により膵管内乳頭粘液性腫瘍併存癌の初期像と診断し得た1例．2022
- Author(s)
  佐藤允洋、唐崎秀則、富永素矢、坂本　淳、木村圭介、太田智之、田中伸哉、水上裕輔.
- Journal Title
  
  日本消化器病学会雑誌
  
  Volume: 119 Pages: 368-376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03655
[Journal Article] A case of incipient pancreatic ductal adenocarcinoma concomitant with intraductal papillary mucinous neoplasm, confirmed by multiregion sequencing analysis2022
- Author(s)
  佐藤允洋、唐崎秀則、富永素矢、坂本淳、木村圭介、太田智之、田中伸哉、水上裕輔
- Journal Title
  
  Nippon Shokakibyo Gakkai Zasshi
  
  Volume: 119 Issue: 4 Pages: 368-376
- DOI
  10.11405/nisshoshi.119.368
- ISSN
  0446-6586, 1349-7693
- Year and Date
  2022-04-10
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-20K09070
[Journal Article] Pathways for the development of multiple epithelial types of intraductal papillary mucinous neoplasm of the pancreas2021
- Author(s)
  Kobayashi Toshikazu、Omori Yuko、Ono Yusuke、Karasaki Hidenori、Mizukami Yusuke、Makino Naohiko、Motoi Fuyuhiko、Unno Michiaki、Ueno Yoshiyuki、Furukawa Toru
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: Online ahead of print Issue: 6 Pages: 581-592
- DOI
  10.1007/s00535-021-01783-2
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16576, KAKENHI-PROJECT-16H05165, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-20H03655
[Journal Article] Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS-mutant and GNAS-wild-type Intraductal Papillary Mucinous Neoplasms of the Pancreas2021
- Author(s)
  Omori Yuko、Ono Yusuke、Morikawa Takanori、Motoi Fuyuhiko、Higuchi Ryota、Yamamoto Masakazu、Hayakawa Yuko、Karasaki Hidenori、Mizukami Yusuke、Unno Michiaki、Furukawa Toru
- Journal Title
  
  Annals of Surgery
  
  Volume: Publish Ahead of Print Issue: 2 Pages: e384-e395
- DOI
  10.1097/sla.0000000000004842
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16576, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-22K08858, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-22K15401, KAKENHI-PROJECT-22KK0125, KAKENHI-PROJECT-23K06759
[Journal Article] 膵癌の初期発生とリキッドバイオプシーによる分子診断2020
- Author(s)
  岡田哲弘　水上裕輔　林明宏　河端秀賢　佐藤裕基　河本徹　後藤拓磨　谷上賢端　小野裕介　唐崎秀則　奥村利勝
- Journal Title
  
  膵臓
  
  Volume: 35 Pages: 302-312
- NAID
  130007893498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09070
[Journal Article] Time-saving method for directly amplifying and capturing a minimal amount of pancreatic tumor-derived mutations from fine-needle aspirates using digital PCR2020
- Author(s)
  Yusuke Ono, Akihiro Hayashi, Chiho Maeda, Mayumi Suzuki, Reona Wada, Hiroki Sato, Hidemasa Kawabata, Tetsuhiro Okada, Takuma Goto, Hidenori Karasaki, Yusuke Mizukami, Toshikatsu Okumura
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 12332-12332
- DOI
  10.1038/s41598-020-69221-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-20H03655
[Journal Article] Genetic Tracing of Clonal Expansion and Progression of Pancreatic Ductal Adenocarcinoma: A Case Report and Multi-Region Sequencing Analysis2020
- Author(s)
  Tachibana Shion、Mizukami Yusuke、Ono Yusuke、Sugiyama Yuya、Okada Tetsuhiro、Kitazaki Arisa、Sasajima Junpei、Tominaga Motoya、Sakamoto Jun、Kimura Keisuke、Omori Yuko、Furukawa Toru、Kimura Taichi、Tanaka Shinya、Nagashima Kazuo、Karasaki Hidenori、Ohta Tomoyuki、Okumura Toshikatsu
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 10 Pages: 1-8
- DOI
  10.3389/fonc.2020.00728
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07441, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-20H03655
[Journal Article] Digital PCR-based plasma cell-free DNA mutation analysis for early-stage pancreatic tumor diagnosis and surveillance2020
- Author(s)
  Okada T, Mizukami Y, Ono Y, Sato H, Hayashi A, Kawabata H, Koizumi K, Masuda S, Teshima S, Takahashi K, Katanuma A, Omori Y, Iwano H, Yamada M, Yokochi T, Asahara S, Kawakubo K, Kuwatani M, Sakamoto N, Enomoto K, Goto T, Sasajima J, Fujiya M, Ueda J, Matsumoto S, Taniue K, Sugitani A, Karasaki H, Okumura T
- Journal Title
  
  J Gastroenterol
  
  Volume: 55 Issue: 12 Pages: 1183-1193
- DOI
  10.1007/s00535-020-01724-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-20H03655, KAKENHI-PROJECT-19K06452
[Journal Article] How does intestinal-type intraductal papillary mucinous neoplasm emerge? CDX2 plays a critical role in the process of intestinal differentiation and progression.2020
- Author(s)
  Omori Y, Ono Y, Kobayashi T, Motoi F, Karasaki H, Mizukami Y, Makino N, Ueno Y, Unno M, Furukawa T.
- Journal Title
  
  Virchows Archiv
  
  Volume: - Issue: 1 Pages: 1-11
- DOI
  10.1007/s00428-020-02806-8
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16576, KAKENHI-PROJECT-16H05410, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20K09070, KAKENHI-PROJECT-20H03655
[Journal Article] Clinical course of conservative management for isolated superior mesenteric arterial dissection2019
- Author(s)
  Sosogi Sho、Sato Ryu、Wada Reona、Saito Hiroya、Takauji Shuhei、Sakamoto Jun、Kimura Keisuke、 Karasaki Hidenori、Mizukami Yusuke、Ohta Tomoyuki
- Journal Title
  
  European Journal of Radiology Open
  
  Volume: 6 Pages: 192-197
- DOI
  10.1016/j.ejro.2019.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09451, KAKENHI-PROJECT-17K09472
[Journal Article] Metachronous intraductal papillary mucinous neoplasms disseminate via the pancreatic duct following resection2019
- Author(s)
  Nagai Kazumasa、Mizukami Yusuke、Omori Yuko、Kin Toshifumi、Yane Kei、Takahashi Kuniyuki、Ono Yusuke、Sugitani Ayumu、Karasaki Hidenori、Shinohara Toshiya、Furukawa Toru、Hayashi Tsuyoshi、Okumura Toshikatsu、Maguchi Hiroyuki、Katanuma Akio
- Journal Title
  
  Modern Pathology
  
  Volume: 33 Issue: 5 Pages: 971-980
- DOI
  10.1038/s41379-019-0405-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09451, KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-20K07671, KAKENHI-PROJECT-20H03655
[Journal Article] Pathways of Progression From Intraductal Papillary Mucinous Neoplasm to Pancreatic Ductal Adenocarcinoma Based on Molecular Features2019
- Author(s)
  Omori Y, Ono Y, Tanino M, Karasaki H, Yamaguchi H, Furukawa T, Enomoto K, Ueda J, Sumi A, Katayama J, Muraki M, Taniue K, Takahashi K, Ambo Y, Shinohara T, Nishihara H, Sasajima J, Maguchi H, Mizukami Y*, Okumura T, Tanaka S.
- Journal Title
  
  Gastroenterology
  
  Volume: 156 Issue: 3 Pages: 647-661
- DOI
  10.1053/j.gastro.2018.10.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-18K07028, KAKENHI-PROJECT-16K07099, KAKENHI-PROJECT-19H01171
[Journal Article] Genetic analysis of postoperative recurrence of pancreatic cancer potentially owing to needle tract seeding during EUS-FNB.2019
- Author(s)
  Kawabata H, Miyazawa Y, Sato H, Okada T, Hayashi A, Iwama T, Fujibayashi S, Goto T, Sasajima J, Takauji S, Fujiya M, Torimoto Y, Tanino M, Omori Y, Ono Y, Karasaki H, Mizukami Y, Okumura T.
- Journal Title
  
  Endosc Int Open.
  
  Volume: 7(12) Issue: 12 Pages: E1768-E1772
- DOI
  10.1055/a-1034-7700
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17480, KAKENHI-PROJECT-17K09451, KAKENHI-PROJECT-17K09472
[Journal Article] 特集　肝胆膵領域とゲノム医療新時代-遺伝子パネルがやってきた！-　IPMNのゲノム解析.2019
- Author(s)
  林　明宏、水上裕輔、佐藤裕基、河端秀賢、岡田哲弘、後藤拓磨、河本　徹、小野裕介、唐崎秀則、奥村利勝.
- Journal Title
  
  肝・胆・膵
  
  Volume: 79 Pages: 1125-1133
- Data Source
  KAKENHI-PROJECT-17K09472
[Journal Article] Utility of “liquid biopsy” using pancreatic juice for early detection of pancreatic cancer2018
- Author(s)
  Okada Tetsuhiro、Iwano Hirotoshi、Ono Yusuke、Karasaki Hidenori、Sato Takayuki、Yamada Masataka、Omori Yuko、Sato Hiroki、Hayashi Akihiro、Kawabata Hidemasa、Goto Takuma、Sasajima Junpei、Takauji Shuhei、Nagashima Kazuo、Mizukami Yusuke、Okumura Toshikatsu
- Journal Title
  
  Endoscopy International Open
  
  Volume: 06 Issue: 12 Pages: E1454-E1461
- DOI
  10.1055/a-0721-1747
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09472
[Journal Article] An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving ‘subsampling’ issues2017
- Author(s)
  Ono Yusuke、Sugitani Ayumu、Karasaki Hidenori、Ogata Munehiko、Nozaki Reo、Sasajima Junpei、Yokochi Tomoki、Asahara Shingo、Koizumi Kazuya、Ando Kiyohiro、Hironaka Katsunori、Daito Tsutomu、Mizukami Yusuke
- Journal Title
  
  Molecular Oncology
  
  Volume: 11 Issue: 10 Pages: 1448-1458
- DOI
  10.1002/1878-0261.12110
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-15K14716
[Presentation] 分子バーコードを用いた十二指腸液由来核酸の変異解析 -より高濃度の変異検出をターゲットとした膵癌リキッドバイオプシー-2022
- Author(s)
  小野裕介、前田知歩、高橋賢治、唐崎秀則、水上裕輔
- Organizer
  第6回 Liquid Biopsy研究会
- Data Source
  KAKENHI-PROJECT-20K07671
[Presentation] High-sensitive mutation detection in liquid biopsy with duodenal fluid captures genetic mutations associated with pancreatic carcinogenesis2022
- Author(s)
  Yusuke Ono, Chiho Maeda, Kenji Takahashi, Hidenori Karasaki, Yusuke Mizukami
- Organizer
  AACR Special Conference; Pancreatic Cancer 2022; Plenary Session 5 "Prevention & Interception"
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07671
[Presentation] 消化液に存在する膵癌由来の遺伝子変異検出を目指したリキッドバイオプシー2022
- Author(s)
  小野裕介, 前田知歩, 高橋賢治, 河端秀賢, 唐崎秀則, 水上裕輔
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07671
[Presentation] Molecular barcode sequencing using duodenal fluid for profiling genomic alterations in pancreatic neoplasms2022
- Author(s)
  Yusuke Ono, Kenji Takahashi, Hidenori Karasaki, Yusuke Mizukami
- Organizer
  Joint congress of the 26th meeting of international association of pancreatology and the 53rd annual meeting of japan pancreas society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07671
[Presentation] 形態的及びゲノムプロファイリングに基づく膵癌前駆病変IPMNの特性.2021
- Author(s)
  水上裕輔、小野裕介、高橋賢治、谷上賢瑞、唐崎秀則、大森優子、古川　徹．
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H03655
[Presentation] 分子バーコードを用いた十二指腸液由来核酸の変異解析 -より高濃度の変異検出をターゲットとした膵癌リキッドバイオプシー--2021
- Author(s)
  小野裕介、前田知歩、高橋賢治、唐崎秀則、水上裕輔
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07671
[Presentation] FEASIBILITY OF DIGITAL PCR-BASED QUANTIFICATION AND MUTATION ANALYSIS OF PLASMA CELL-FREE DNA FOR DIAGNOSIS AND SURVEILLANCE OF EARLY-STAGE PANCREATIC TUMORS.2020
- Author(s)
  Okada T, Mizukami Y, Koizumi K, Takahashi K, Iwano H, Asahara S, Kuwatani M, Kawamoto T, Sato H, Hayashi A, Kawabata H, Goto T, Sasajima J, Fujiya M, Ono Y, Karasaki H, Okumura T.
- Organizer
  DDW2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09070
[Presentation] STK11 plays a canonical role in malignant progression of a subset of KRAS-mutant IPMNs.2020
- Author(s)
  大森優子、小野裕介、森川孝則、元井冬彦、樋口亮太、山本雅一、唐崎秀則、水上裕輔、海野倫明、古川　徹．
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20H03655
[Presentation] FEASIBILITY OF DIGITAL PCR-BASED QUANTIFICATION AND MUTATION ANALYSIS OF PLASMA CELL-FREE DNA FOR DIAGNOSIS AND SURVEILLANCE OF EARLY-STAGE PANCREATIC TUMORS.2020
- Author(s)
  Okada T, Mizukami Y, Koizumi K, Takahashi K, Iwano H, Asahara S, Kuwatani M, Kawamoto T, Sato H, Hayashi A, Kawabata H, Goto T, Sasajima J, Fujiya M, Ono Y, Karasaki H, Okumura T.
- Organizer
  DDW2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03655
[Presentation] STK11 Plays a Canonical Role in Malignant Progression of a Subset of KRAS-mutant Intraductal Papillary Mucinous Neoplasms.2020
- Author(s)
  Omori Y, Ono Y, Morikawa T, Motoi F, Higuchi R, Yamamoto M, Karasaki K, Mizukami Y, Unno M. Furukawa T.
- Organizer
  109th USCAP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03655
[Presentation] STK11 plays a canonical role in malignant progression of a subset of KRAS-mutant IPMNs.2020
- Author(s)
  大森優子、小野裕介、森川孝則、元井冬彦、樋口亮太、山本雅一、唐崎秀則、水上裕輔、海野倫明、古川　徹．
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K09070
[Presentation] STK11 Plays a Canonical Role in Malignant Progression of a Subset of KRAS-mutant Intraductal Papillary Mucinous Neoplasms.2020
- Author(s)
  Omori Y, Ono Y, Morikawa T, Motoi F, Higuchi R, Yamamoto M, Karasaki H, Mizukami Y, Unno M, Furukawa T.
- Organizer
  109th USCAP Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09070
[Presentation] 血漿遊離核酸を用いた膵腫瘍診断2019
- Author(s)
  岡田哲弘、水上裕輔、河本　徹、林　明宏、佐藤裕基、河端秀賢、後藤拓磨、笹島順平、小泉一也、高橋邦幸、岩野博俊、浅原新吾、桑谷将城、唐崎秀則、奥村利勝.
- Organizer
  第50回日本膵臓学会大会
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] PATHWAYS OF PROGRESSION FROM INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM AND THE GENETIC DIVERSITY OF ASSOCIATED ORGAN FIELD.2019
- Author(s)
  Mizukami Y, Omori Y, Ono Y, Karasaki H, Tanino M, Yamaguchi H, Furukawa T, Maguchi H, Tanaka S, Okumura T.
- Organizer
  DDW2019米国消化器病週間
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] Capturing Pancreatic Tumor-derived Mutations from Fine Needle Aspiration Using Digital PCR.2019
- Author(s)
  Ono Y, Hayashi A, Wada R, Suzuki M, Maeda C, Okada T, Sato H, Kawabata H, Goto T, Karasaki H, Mizukami Y, Okumura T.
- Organizer
  The 50th Anniversary Joint Meeting of APA & JPS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] The Temporal Order of KRAS and GNAS Mutations in Intraductal Papillary Mucinous Neoplasms of the Pancreas and Evolution to Invasive Carcinoma.2019
- Author(s)
  Mizukami Y, Karasaki H, Ono Y, Omori Y, Hayashi A, Tachibana S, Sugiyama Y, Sato H, Kawabata H, Goto T, Fujiya M, Takahashi K, Katanuma A, Maguchi H, Furukawa T, Okumura T.
- Organizer
  The 50th Anniversary Joint Meeting of APA & JPS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] デジタルPCRを用いた血漿遊離核酸からの膵腫瘍の検出－早期診断への活用に向けて－ Screening of mutations in circulating cell-free DNA for early-stage diagnosis and surveillance of pancreatic tumors.2019
- Author(s)
  小野裕介、唐崎秀則、水上裕輔.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] IPMN関連膵癌の分子基盤と進展経路.2019
- Author(s)
  水上裕輔、大森優子、唐崎秀則.
- Organizer
  第50回日本膵臓学会大会　パネルディスカッション
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] A revised model of clonal evolution of intraductal papillary mucinous neoplasm-related pancreatic carcinogenesis2018
- Author(s)
  Mizukami Y, Omori Y, Ono Y, Karasaki H, Tanino M, Yamaguchi H, Furukawa T, Takahashi K Ambo Y, Shinohara T, Sasajima J, Tanaka S, Maguchi H
- Organizer
  Digestive Disease Week 2018. Research Forum: Pancreatic Cystic Neoplasms, IPMN and Neuroendocrine Tumors
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] Diversity of precursor lesions for pancreatic cancer: Genetics and biology of intraductal papillary mucinous neoplasm.2018
- Author(s)
  Mizukami Y, Ono Y, Karasaki H, Omori Y, Ueda J, Okumura T
- Organizer
  第77回日本癌学会学術総会　腫瘍別シンポジウム 2：胆肝膵悪性腫瘍における現況と展望
- Invited
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] Plasma DNA genotyping using digital PCR for surveillance of pancreatic cancer in high-risk individuals2017
- Author(s)
  Mizukami Y、Ono Y、Karasaki H、Koizumi K、Okada T、Sasajima J、Yamada M、Asahara S、Kawakubo K、Maguchi H
- Organizer
  25th UEG Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] 血漿遊離核酸を用いた膵腫瘍悪性度診断2017
- Author(s)
  岡田哲弘、水上裕輔、笹島順平、小野裕介、唐崎秀則、他
- Organizer
  第25回日本消化器病関連学会週間
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] An improved digital polymerase chain reaction protocol to capture low-copy KRAS mutations in plasma cell-free DNA by resolving ”subsampling”issues2017
- Author(s)
  Ono Y、Sugitani A、Karasaki H、Ogata M、Nozaki R、Sasajima J、Mizukami Y
- Organizer
  25th UEG Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] Concomitant pancreatic cancers arising adjacent to index IPMN share identical KRAS mutations and are associated with a favorable prognosis2017
- Author(s)
  Omori Y、Ono Y、Tanino M、Karasaki H、Shinohara T、Tanaka S、Maguchi H、Mizukami Y
- Organizer
  25th UEG Week
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] Improved digital PCR protocol to capture low-copy KRAS mutations in plasma cell-free DNA by pre-amplification 血漿由来遊離核酸より微量変異を検出する感度の向上を目的としたデジタルPCR法の応用2017
- Author(s)
  Ono Y、Karasaki H、Sasajima J、Mizukami Y
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09472
[Presentation] Digital PCR-based liquid biopsy for early detection of pancreatic cancer2017
- Author(s)
  Mizukami Y、Ono Y、Karasaki H、Okada T、Sasajima J
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09472

1. Mizukami Yusuke (30400089)

# of Collaborated Projects: 5 results

# of Collaborated Products: 39 results
2. Ono Yusuke (40742648)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
3. IMAI KOJI (10516420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 笹島順平 (80451467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. 谷上賢瑞 (90648627)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. KIMURA Taichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 林明宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 大森優子

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
9. 高橋賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐藤裕基

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Karasaki Hidenori 唐崎 秀則

Research Projects

Research Products

Co-Researchers

Study for novel biomarker in liquid biopsy on on carcinogenic pathways induced by driver mutations

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanisms responsible for IPMNs progression

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Distribution and clonality of multiple intraductal neoplasms of the pancreas evaluated by morphologyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Early diagnosis of pancreatic cancer based on diversity of field defect and molecular genetic approach

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Diversity of molecular paths during pancreatic carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Multiplex Digital PCR Assay to Detect Multiple KRAS and GNAS Mutations Associated with Pancreatic Carcinogenesis from Minimal Specimen Amounts2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mutant GNAS limits tumor aggressiveness in established pancreatic cancer via antagonizing the KRAS-pathway2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictors of Long-Term Survival in Pancreatic Ductal Adenocarcinoma after Pancreatectomy: TP53 and SMAD4 Mutation Scoring in Combination with CA19-92022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct effects of TU-100 (daikenchuto) on long-lasting dysbiosis in the small intestine in patients with colorectal cancer and inflammatory bowel disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ゲノム解析により膵管内乳頭粘液性腫瘍併存癌の初期像と診断し得た1例．2022

Author(s)

Journal Title

Data Source

[Journal Article] A case of incipient pancreatic ductal adenocarcinoma concomitant with intraductal papillary mucinous neoplasm, confirmed by multiregion sequencing analysis2022

Author(s)

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DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Pathways for the development of multiple epithelial types of intraductal papillary mucinous neoplasm of the pancreas2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Serine/Threonine Kinase 11 Plays a Canonical Role in Malignant Progression of KRAS-mutant and GNAS-wild-type Intraductal Papillary Mucinous Neoplasms of the Pancreas2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 膵癌の初期発生とリキッドバイオプシーによる分子診断2020

Author(s)

Journal Title

NAID

Karasaki Hidenori 唐崎秀則

[Journal Article] 特集　肝胆膵領域とゲノム医療新時代-遺伝子パネルがやってきた！-　IPMNのゲノム解析.2019

[Presentation] 分子バーコードを用いた十二指腸液由来核酸の変異解析 -より高濃度の変異検出をターゲットとした膵癌リキッドバイオプシー-2022