Oota Tsuyoshi 太田剛

… Alternative Names

OHTA Tsuyoshi 太田剛

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Researcher Number	50375341
Other IDs
Affiliation (Current)	2025: 山形大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 山形大学, 医学部, 准教授 2016 – 2020: 山形大学, 医学部, 講師 2008 – 2015: Yamagata University, 医学部, 助教 2007: Yamagata University, 医学部, 医員
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 卵巣癌 / 薬剤耐性 / 細胞接着 / ハニカム膜 / Wilms' tumor 1 / 癌幹細胞 / 再発 / 代謝リプログラミング / メタボローム解析 / 抗腫瘍免疫能 … More / 薬剤感受性 / がんの発生 / ポリアミン代謝経路 / トランスクリプトーム / オミクス解析 / ポリアミン / メタボローム / 卵巣がん / circulating tumor cell / 細胞サイズ / 腫瘍形成 / 細胞膜受容体 / 細胞骨格 / RNA sequence / 腫瘍増殖 / 卵巣癌幹細胞 / 細胞増殖 / 生体親和性多孔性膜 / 発がん / 腹水 / WT1 isoform / 血管新生 / VEGF / 腫瘍産生 / Wilms' tumor 1 (WT1) / yin and yang 1 / 分子標的治療 / DNA repair / Gefitinib / DNA-PK / ERK / Akt / gefitinib / EGFR … More Except Principal Investigator 卵巣癌 / メタボローム解析 / パクリタキセル / 抗がん剤耐性 / ハニカム膜 / 薬剤耐性 / 腹膜播種 / アミノ酸代謝 / 子宮内膜 / フェロトーシス / スルファサラジン / パクリタキセル耐性 / 卵巣癌幹細胞 / 細胞接着 / 細胞増殖 / microRNA / 卵巣明細胞腺癌 / 卵巣がん / バイオインフォマティクス / トランスクリプトーム解析 / MED12 / レルゴリクス / 子宮筋腫 / ポリアミン経路 / 腹水 / Treg細胞 / 免疫寛容 / 着床 / 不妊 / プロピオン酸 / 妊娠 / 短鎖脂肪酸 / 制御性T細胞 / 胚着床 / 不妊症 / 生殖医療 / 活性酸素種 / 治療抵抗性 / 卵巣明細胞癌 / 化学療法抵抗性 / グルタチオン / 明細胞癌 / xenograftモデル / オルガノイド / PDX / アスパラギン代謝経路 / PDXオルガノイド / 抗がん剤 / 生殖内分泌学 / 分子生物学 / 婦人科腫瘍学 / エストロゲン / エストロゲン受容体 / 核内受容体転写補助因子 / Ncoa6 / 転写補助因子 / 子宮体癌 / 脱落膜化 / 子宮体部漿液性腺癌 / 子宮体部漿液性癌 / 低酸素 / エピジェネティク / 薬剤感受性 / ポリコーム複合体 / 癌幹細胞 / AKT-mTORシグナル / トラベクテジン / 薬剤耐性化機構 / メタボロミクス / オートファジー / mTOR / Trabectedin / EGF受容体 / Rho/ROCK経路 / 薬剤耐性化 / 播腫 / 間質 / 幹細胞 / 機能性間質 / サイトカイン / マイクロRNA / 分子標的治療 / 性ステロイド Less

Elucidation of the mechanisms of recurrence and drug resistance in ovarian cancer based on metabolic reprogramming, and the development of novel therapiesPrincipal Investigator
- Principal Investigator
  
  太田剛
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
アミノ酸代謝リプログラミングを標的とした卵巣癌転移機構の解明と新規治療法の開発
- Principal Investigator
  
  永瀬智
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Research on the molecular genetic mechanism of the uterine fibroid volume reduction effect of relugolix
- Principal Investigator
  
  松川淳
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Establishment of a novel therapeutic strategy for drug-resistant ovarian cancer focusing on the glutathione synthesis pathway
- Principal Investigator
  
  Seino Manabu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Development of a therapeutic strategy for female infertility by induction of intrauterine Treg cells by administration of short-chain fatty acids.
- Principal Investigator
  
  Kawagoe Jun
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Development of Novel Therapies for Ovarian Cancer by Targeting the Polyamine Metabolic PathwayPrincipal Investigator
- Principal Investigator
  
  OHTA TSUYOSHI
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Development of Novel Therapeutic Methods Based on Metabolomic and Genetic Analysis for the Control of Ovarian Cancer Cachexia
- Principal Investigator
  
  Nagase Satoru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Novel therapeutic development based on metabolomic analysis to overcome the recurrent ovarian cancer with anti-cancer drug resistance
- Principal Investigator
  
  Nagase Satoru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Yamagata University
Development of new treatment and diagnostic method for ovarian cancer using biocompatible porous membrane (honeycomb films)Principal Investigator
- Principal Investigator
  
  OTA TSUYOSHI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The functional analysis of the nuclear receptor coactivator-6 (Ncoa6) which may modulate the estrogen sensitivity in the human endometrium and involves in the development of endometrial cancer.
- Principal Investigator
  
  Kawagoe Jun
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
Development of novel therapeutic strategies based on metabolomics analysis of uterine serous carcinoma
- Principal Investigator
  
  Nagase Satoru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The possibility of 3D porous scaffold honeycomb films for the new strategy of treatment with ovarian cancerPrincipal Investigator
- Principal Investigator
  
  OHTA Tsuyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The role of epigenetic effector polycomb group gene in ovarian cancers
- Principal Investigator
  
  SUDO Takeshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
Establishment and functional analysis of induced pluripotent cancer cells in ovarian cancer
- Principal Investigator
  
  KURACHI Hirohisa
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The possibility of WT1 gene for new therapeutic target in ovarian cancerPrincipal Investigator
- Principal Investigator
  
  OHTA Tsuyoshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The identification of drug resistance in ovarian cancer : new insights form metabolomics and autophagy
- Principal Investigator
  
  KURACHI HIROHISA
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The new molecular targeting therapy against the cancer stem cell in ovarian cancersPrincipal Investigator
- Principal Investigator
  
  TSUYOSHI Ohta
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
卵巣癌の間葉系幹細胞の同定と機能解析―その分子標的治療に向けての基礎的研究
- Principal Investigator
  
  倉智博久
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University
The clarification of drug-resistance and the development of new targeting therapies in ovarian cancerPrincipal Investigator
- Principal Investigator
  
  OHTA Tsuyoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Yamagata University

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All Journal Article Presentation Book

[Book] [子宮体がん診療アップデート] 診断のトピックス子宮体がん発症のリスク因子2013
- Author(s)
  竹原功, 太田剛, 倉智博久
- Publisher
  臨床婦人科産科
- Data Source
  KAKENHI-PROJECT-24791680
[Book] 産婦人科手術・処置とトラブル対処法2010
- Author(s)
  中原健次, 太田剛, 倉智博久
- Total Pages
  324
- Publisher
  婦人科手術開腹手術 [キーワード:卵巣腫瘍摘出術] ここが聞きたい
- Data Source
  KAKENHI-PROJECT-22390308
[Book] 産婦人科手術・処置とトラブル対処法2010
- Author(s)
  中原健次, 太田剛, 倉智博久
- Total Pages
  324
- Publisher
  婦人科手術開腹手術 [キーワード:卵巣腫瘍摘出術] ここが聞きたい
- Data Source
  KAKENHI-PROJECT-21659379
[Journal Article] Mechanism of Cell Death by Combined Treatment with an xCT Inhibitor and Paclitaxel: An Alternative Therapeutic Strategy for Patients with Ovarian Clear Cell Carcinoma2023
- Author(s)
  Idei Urara、Ohta Tsuyoshi、Yamatani Hizuru、Seino Manabu、Nagase Satoru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 14 Pages: 11781-11781
- DOI
  10.3390/ijms241411781
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09440
[Journal Article] Nuclear receptor coactivator‐6 is essential for the morphological change of human uterine stromal cell decidualization via regulating actin fiber reorganization2022
- Author(s)
  Watanabe Norikazu、Kawagoe Jun、Sugiyama Akiko、Takehara Isao、Ohta Tsuyoshi、Nagase Satoru
- Journal Title
  
  Molecular Reproduction and Development
  
  Volume: 89 Issue: 4 Pages: 165-174
- DOI
  10.1002/mrd.23568
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09488
[Journal Article] xCT inhibitor sulfasalazine depletes paclitaxel-resistant tumor cells through ferroptosis in uterine serous carcinoma.2020
- Author(s)
  Sugiyama A, Ohta T, Obata M, Takahashi K, Seino M, Nagase S.
- Journal Title
  
  Oncol Lett.
  
  Volume: 20(3) Issue: 3 Pages: 2689-2700
- DOI
  10.3892/ol.2020.11813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09217
[Journal Article] GSKJ4, A Selective Jumonji H3K27 Demethylase Inhibitor, Effectively Targets Ovarian Cancer Stem Cells.2015
- Author(s)
  Sakaki H, Okada M, Kuramoto K, Takeda H, Watarai H, Suzuki S, Seino S, Seino M, Ohta T, Nagase S, Kurachi H, Kitanaka C.
- Journal Title
  
  Anticancer Res
  
  Volume: 35 Pages: 6607-6614
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10699
[Journal Article] 子宮頸部神経内分泌癌6例の解析2014
- Author(s)
  長谷川　歩美、太田　剛、倉智　博久
- Journal Title
  
  臨床婦人科産科
  
  Volume: 68 Pages: 165-170
- NAID
  40019926489
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791680
[Journal Article] Non-sex cord-stromal ovarian tumors frequently produce and secrete estrogen in postmenopausal women : impact on bone metabolism and abnormal endometrial histology2013
- Author(s)
  Matsumura S, Ohta T, Takahashi T, T Kurachi H
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 98(7) Issue: 7 Pages: 2775-2782
- DOI
  10.1210/jc.2013-1267
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308, KAKENHI-PROJECT-24659723, KAKENHI-PROJECT-24791680, KAKENHI-PROJECT-25340047
[Journal Article] Non-sex cord-stromal ovarian tumors frequently produce and secrete estrogen in postmenopausal women:impact on bone metabolism and abnormal endometrial histology.2013
- Author(s)
  Matsumura S, Ohta T, Takahashi T, T Kurachi H. （他2名、6番目）
- Journal Title
  
  J Clin Endocrinol Metab
  
  Volume: 98 Pages: 2775-2782
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308
[Journal Article] 子宮頸部神経内分泌癌 6 例の解析2013
- Author(s)
  長谷川歩美, 太田剛, 倉智博久
- Journal Title
  
  臨床婦人科産科
  
  Volume: 68(1) Pages: 165-170
- NAID
  40019926489
- URL
  http://search.jamas.or.jp/index.php
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791680
[Journal Article] Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells2012
- Author(s)
  太田剛、高橋俊文、倉智博久
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 13 Pages: 25-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Gefitinib (ZD1839) increases the efficacy of cisplatin in ovarian cancer cells2012
- Author(s)
  Ohta T, Takahashi T, Kurachi H
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 13(6) Issue: 6 Pages: 408-416
- DOI
  10.4161/cbt.19292
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308, KAKENHI-PROJECT-24659723, KAKENHI-PROJECT-24791680
[Journal Article] 婦人科腫瘍との鑑別が困難であったGISTの2例.2012
- Author(s)
  松村創平,太田剛,水谷雅臣,蜂谷修,木村理,菅井幸雄,高橋一広,倉智博久.
- Journal Title
  
  臨床婦人科産科
  
  Volume: 66（9） Pages: 799-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308
[Journal Article] Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1α in human ovarian cancer cells2012
- Author(s)
  Ohta T, Takahashi T, Kurachi H
- Journal Title
  
  Cacer Biol Ther
  
  Volume: 13(7) Issue: 1 Pages: 1-9
- DOI
  10.4161/cbt.13.1.18440
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308, KAKENHI-PROJECT-24659723, KAKENHI-PROJECT-24791680
[Journal Article] 婦人科腫瘍との鑑別が困難であったGISTの2例.2012
- Author(s)
  松村創平,太田剛,水谷雅臣,蜂谷修,木村理,菅井幸雄,高橋一広,倉智博久.
- Journal Title
  
  臨床婦人科産科
  
  Volume: 66(9) Pages: 799-802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659723
[Journal Article] 婦人科腫瘍との鑑別が困難であったGIST の 2 例2012
- Author(s)
  松村創平, 太田剛, 水谷雅臣, 蜂谷修, 木村理, 菅井幸雄, 高橋一広, 倉智博久
- Journal Title
  
  臨床婦人科産科
  
  Volume: 66(9) Pages: 799-802
- URL
  http://search.jamas.or.jp/index.php
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791680
[Journal Article] Estrogen induces neurite outgrowth via Rho family GTPases in neuroblastoma cells2011
- Author(s)
  高橋一広、太田剛、倉智博久
- Journal Title
  
  Molecular Cell Neuroscience
  
  Volume: 48 Pages: 217-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Inhibition of the Rho/ROCK pathway enhances the efficacy of cisplatin through the blockage of hypoxia-inducible factor-1alpha in human ovarian cancer cells2011
- Author(s)
  Ohta T, Takahashi T, Shibuya T, Amita M, Henmi N, Takahashi K, Kurachi H.
- Journal Title
  
  Cancer Biol Ther
  
  Volume: 13(1) Pages: 25-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Estrogen induces neurite outgrowth via Rho family GTPases in neuroblastoma cells2011
- Author(s)
  Takahashi K, Piao S, Yamatani H, Du B, Yin L, Ohta T, Kawagoe J, Takata K, Tsutsumi S, Kurachi H
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 48 Issue: 3 Pages: 217-224
- DOI
  10.1016/j.mcn.2011.08.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308
[Journal Article] Estrogen induces neurite outgrowth via Rho family GTPases in neuroblastoma cells2011
- Author(s)
  Takahashi K, Piao S, Yamatani H, Du B, Yin L, Ohta T, Kawagoe J, Takata K, Tsutsumi S, Kurachi H.
- Journal Title
  
  Mol Cell Neurosci
  
  Volume: 48(3) Pages: 217-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate2010
- Author(s)
  Amita M, Takahashi T, Tsutsumi S, Ohta T, Takata K, Henmi N, Hara S, Igarashi H, Takahashi K, Kurachi H.
- Journal Title
  
  Endocrinology
  
  Volume: 151(1) Pages: 394-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Effect of dienogest on estrogen-induced nitric oxide production in human umbilical vein endothelial cells and endothelium-dependent vasodilatation in postmenopausall women2010
- Author(s)
  Henmi N, Takahashi K, Amita M, Takata K, Ohta T, Tsutsumi S, Takahashi T, Kurachi H.
- Journal Title
  
  Menopose
  
  Volume: 17(3) Pages: 615-621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate2010
- Author(s)
  Amita M, Takahashi T, Ohta T, Takata K, Kurachi H
- Journal Title
  
  Endocrinology
  
  Volume: 151(1) Issue: 1 Pages: 394-405
- DOI
  10.1210/en.2009-0721
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308, KAKENHI-PROJECT-24659723
[Journal Article] Effect of dienogest on estrogen-induced nitric oxide production in human umbilical vein endothelial cells, and endothelium-dependent vasodilatation in postmenopausal women.2010
- Author(s)
  Henmi N, Takahashi K, Takata K, Ohta T, Tsutsumi S, Takahashi T, Kurachi H.
- Journal Title
  
  Menopause (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659379
[Journal Article] Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate.2010
- Author(s)
  Amita M, Takahashi T, Tsutsumi S, Ohta T, Takata K, Henmi N, Hara S, Igarashi K, Takahashi K, Kurachi H.
- Journal Title
  
  Endocrinology
  
  Volume: 151 Pages: 394-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390308
[Journal Article] Molecular mechanism of the inhibition of estradiol-induced endometrial epithelial cell proliferation by clomiphene citrate.2010
- Author(s)
  Amita M, Takahashi T, Tsutsumi S, Ohta T, Takata K, Henmi N, Hara S, Igarashi H, Takahashi K, Kurachi H.
- Journal Title
  
  Endocrinology 151(1)
  
  Pages: 394-405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659379
[Journal Article] The Akt and ERK activation by platinum-based chemotherapy in ovarian cancer is associated with favorable patient outcome.2009
- Author(s)
  太田剛
- Journal Title
  
  Anti-Cancer Research 29
  
  Pages: 4639-4647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] The Akt and ERK activation by platinum-based chemotherapy in ovarian cancer is associated with favorable patient outcome.2009
- Author(s)
  Ohta T, Isobe M, Takahashi T, Saitoh-Sekiguchi M, Motoyama T, Kurachi H.
- Journal Title
  
  Anticancer Res 29(11)
  
  Pages: 4639-4647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21659379
[Journal Article] The Akt and ERK activation by platinum-based chemotherapy in ovarian cancer is associated with favorable patient outcome2009
- Author(s)
  Ohta T, Isobe M, Takahashi T, Saitoh-Sekiguchi M, Motoyama T, Kurachi H.
- Journal Title
  
  Anticancer Res
  
  Volume: 29(11) Pages: 4639-4647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592122
[Journal Article] Fasudil-induced hypoxia-incucible factor 1-alp ha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine me chanism in endothelial cells2008
- Author(s)
  高田恵子、太田剛、倉智博久
- Journal Title
  
  Molecular cancer therapeutics 7(6)
  
  Pages: 1551-1561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19791135
[Presentation] グルタチオン代謝経路阻害剤とpaclitaxelの併用による細胞死誘導機構に関する検討2023
- Author(s)
  出井麗、太田剛、伊藤泰史、堀川翔太、榊宏諭、清野学、永瀬智
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09440
[Presentation] 卵巣癌の腹水メタボローム解析に関する検討2023
- Author(s)
  堀川翔太、立花由花、奥井陽介、榊宏諭、清野学、太田剛、永瀬智
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09532
[Presentation] 卵巣癌の腹水メタボローム解析に関する検討2023
- Author(s)
  堀川　翔太、奥井　陽介、立花　由花、榊　宏諭、清野　学、太田　剛、永瀬　智
- Organizer
  第75回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09532
[Presentation] メタボロミクスによる卵巣癌組織と生体試料における代謝経路に関する検討2023
- Author(s)
  太田　剛、立花　由花、堀川　翔太、奥井　陽介、榊　宏諭、清野　学、砂村　真琴、杉本　昌弘、永瀬　智
- Organizer
  第65回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09532
[Presentation] メタボロミクスによる卵巣癌組織と生体試料における代謝経路に関する検討2023
- Author(s)
  太田　剛、立花　由花、堀川　翔太、奥井　陽介、榊　宏諭、清野　学、砂村　真琴、杉本　昌弘、永瀬　智
- Organizer
  第65回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09509
[Presentation] グルタチオン代謝経路阻害剤とpaclitaxelの併用による細胞死誘導機構に関する検討2022
- Author(s)
  出井麗、太田剛、伊藤泰史、堀川翔太榊宏諭、清野学、永瀬智
- Organizer
  第74回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-21K09440
[Presentation] パクリタキセル長期暴露卵巣癌細胞におけるアスパラギン代謝経路に関する研究2021
- Author(s)
  鈴木百合子、清野学、太田剛、永瀬智
- Organizer
  第62回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09217
[Presentation] 卵巣癌および子宮体癌患者における酸化ストレスに関する検討2021
- Author(s)
  清野学、太田剛、永瀬智
- Organizer
  第62回日本婦人科腫瘍学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09217
[Presentation] 子宮体癌細胞株に対するスルファサラジンおよびシスプラチンの併用効果の検討2020
- Author(s)
  髙橋可菜子、太田剛、清野学、永瀬智
- Organizer
  第19回日本婦人科がん分子標的研究会
- Data Source
  KAKENHI-PROJECT-18K09217
[Presentation] xCT inhibitor sulfasalazine enhances the efficacy of cisplatin in human uterine serous carcinoma2020
- Author(s)
  Kanako Takahashi, Manabu Seino, Urara Idei, Tsuyoshi Oota, Satoru Nagase
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09217
[Presentation] Low-dose paclitaxel induces asparagine synthetase expression and increases cell proliferation in ovarian cancer cells2020
- Author(s)
  Manabu Seino, Tsuyoshi Ohta, Yousuke Okui, Yuriko Suzuki, Takeshi Sudou, Satoru Nagase
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09217
[Presentation] Metabolome analysis for discovering new therapeutic target of ovarian cancer cells treated with paclitaxel.2019
- Author(s)
  eino M, Oota T, Okui Y, Suzuki Y, Sakaki H, Sudo T, Nagase S
- Organizer
  第71回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18K09217
[Presentation] 子宮体部漿液性腺癌細胞株におけるスルファサラジンによるパクリタキセル抵抗性解除機構に関する検討2017
- Author(s)
  杉山晶子,太田剛,榊宏諭,清野学,須藤毅,永瀬智.
- Organizer
  第69回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-15K10699
[Presentation] Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel.2017
- Author(s)
  Seino M, Ohta T, Sugiyama A, Sakaki H, Sudo T, Nagase S.
- Organizer
  The 5th Biennial Meeting of Asian Society of Gynecologic Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10699
[Presentation] 子宮体部漿液性癌のタキサン耐性獲得に関するメタボローム解析2017
- Author(s)
  清野学,太田剛,杉山晶子,榊宏諭,須藤毅,永瀬智.
- Organizer
  第69回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-15K10699
[Presentation] Evaluation of preventive methods for the symptomatic pulmonary thromboembolism by postoperative anticoagulant therapy in VTE high risk patients with gynecologic malignancy2013
- Author(s)
  Takahashi T, Seino M, Ohta T, Sudo T, Ishida H, Kurachi H
- Organizer
  第65回日本産科婦人科学会
- Place of Presentation
  ホテル札幌芸文館(札幌市)
- Data Source
  KAKENHI-PROJECT-24791680
[Presentation] 婦人科悪性腫瘍治療が骨密度に与える影響についての経時的追跡.2013
- Author(s)
  高橋一広, 山谷日鶴, 吉田隆之, 太田剛, 倉智博久.
- Organizer
  第54回日本婦人科腫瘍学会
- Place of Presentation
  ホテルグランパシフィック LE DAIBA（東京都）
- Data Source
  KAKENHI-PROJECT-24659723
[Presentation] 卵巣癌におけるWT1 isoformの発現とその薬剤感受性に関する検討2012
- Author(s)
  太田剛
- Organizer
  第52回日本婦人科腫瘍学会
- Place of Presentation
  ｸﾞﾗﾝﾄﾞﾌﾟﾘﾝｽﾎﾃﾙ新高輪(東京都）
- Data Source
  KAKENHI-PROJECT-24791680
[Presentation] The role of YY1 in paclitaxel-induced cytotoxicity in epithelial ovarian cancer2012
- Author(s)
  Ohta T, Ota T, Chien J, Shridhar V, Kurachi H
- Organizer
  AACR
- Place of Presentation
  McCormic Place in Chicago, IL, USA
- Data Source
  KAKENHI-PROJECT-24791680
[Presentation] Flavopiridol-induced upregulation of HtrA1 is associated with suppression of its negative regulator WT1 and with enhanced chemosensitivity2011
- Author(s)
  太田剛
- Organizer
  米国癌学会(American Association for Cancer Research)
- Place of Presentation
  Orlando, Florida
- Year and Date
  2011-04-05
- Data Source
  KAKENHI-PROJECT-21592122
[Presentation] Flavopiridol-induced upregulation of HtrA1 is associated with suppression of its negative transcriptional regulator WT1 and with enhanced chemosensitivity2011
- Author(s)
  Ohta T, Khurana A, Maguire J, He X, Chien J, Bible K, Shridhar V.
- Organizer
  AACR
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-21592122
[Presentation] Regulation of HtrA1 expression by WT1 is associated with chemosensitivity in ovarian cancer cells2011
- Author(s)
  太田剛、倉智博久
- Organizer
  日本癌学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21592122
[Presentation] 卵巣癌細胞におけるWT1によるHtrA1の制御機構と薬剤感受性の関連2011
- Author(s)
  太田剛
- Organizer
  第70回日本癌学会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-21592122
[Presentation] 化学療法後の卵巣癌再発巣におけるAktとERKの活性化は予後良好因子である2010
- Author(s)
  清野学, 太田剛, 高橋俊文, 逸見典子, 須藤毅, 本山悌一, 倉智博久
- Organizer
  第62回日本産科婦人科学会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-22390308
[Presentation] 化学療法後の卵巣癌再発巣におけるAktとERKの活性化は予後良好因子である2010
- Author(s)
  清野学、太田剛、高橋俊文、逸見典子、須藤毅、本山悌一、倉智博久
- Organizer
  第62回日本産科婦人科学会
- Place of Presentation
  東京国際フォーラム(東京都)
- Data Source
  KAKENHI-PROJECT-24659723
[Presentation] 卵巣癌細胞におけるHIF-1阻害によるシスプラチンの抗腫瘍効果増強作用についての検討2009
- Author(s)
  太田剛
- Organizer
  第61回日本産科婦人科学会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21592122
[Presentation] 卵巣癌細胞におけるHIF-1阻害によるシスプラチンの抗腫瘍効果増強作用についての検討2009
- Author(s)
  太田剛
- Organizer
  第61回日本産科婦人科学会学術講演会
- Place of Presentation
  京都、国立京都国際会館
- Year and Date
  2009-04-05
- Data Source
  KAKENHI-PROJECT-21592122
[Presentation] 卵巣癌細胞におけるGefitinibによるシスプラチンの抗腫瘍効果増強作用についての検討2008
- Author(s)
  太田剛
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-04-13
- Data Source
  KAKENHI-PROJECT-19791135

1. Nagase Satoru (00292326)

# of Collaborated Projects: 10 results

# of Collaborated Products: 19 results
2. Seino Manabu (40594320)

# of Collaborated Projects: 9 results

# of Collaborated Products: 17 results
3. KURACHI Hirohisa (40153366)

# of Collaborated Projects: 6 results

# of Collaborated Products: 25 results
4. SAWADA Kenjiro (00452392)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. TAKAHASHI Toshifumi (20302292)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
6. SUTOH Takeshi (70466605)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. TAKATA Keiko (70375343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
8. Kawagoe Jun (60375342)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
9. 竹原功 (80642496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. YOSHIDA Takayuki (60466604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MABUCHI Seiji (00452441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TAKAHASHI Kazuhiro (20292427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. 堤誠司 (50323168)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 鈴木史彦 (20400343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
15. 榊宏諭 (80744458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 松川淳 (50743548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. WATANABE Norikazu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Oota Tsuyoshi 太田 剛

OHTA Tsuyoshi 太田 剛

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Elucidation of the mechanisms of recurrence and drug resistance in ovarian cancer based on metabolic reprogramming, and the development of novel therapiesPrincipal Investigator

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Development of Novel Therapies for Ovarian Cancer by Targeting the Polyamine Metabolic PathwayPrincipal Investigator

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Development of new treatment and diagnostic method for ovarian cancer using biocompatible porous membrane (honeycomb films)Principal Investigator

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The possibility of 3D porous scaffold honeycomb films for the new strategy of treatment with ovarian cancerPrincipal Investigator

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The possibility of WT1 gene for new therapeutic target in ovarian cancerPrincipal Investigator

Oota Tsuyoshi 太田剛

OHTA Tsuyoshi 太田剛

[Book] [子宮体がん診療アップデート] 診断のトピックス子宮体がん発症のリスク因子2013