Sakoda Hideyuki 迫田秀之

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SAKODA Hideyuki 迫田秀之

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Researcher Number	50376464
Other IDs
Affiliation (based on the past Project Information) *help	2020 – 2023: 宮崎大学, 医学部, 准教授 2014 – 2018: 宮崎大学, 医学部, 講師 2016: 東京大学, 附属病院, 助教 2015: 宮崎大学, 医学部附属病院, 講師 2015: 宮崎大学, 第三内科, 講師 … More 2012 – 2013: 東京大学, 医学部附属病院, 講師 2012: 東京大学, 医学部附属病院, 特任講師 2010 – 2011: 東京大学, 大学病院, 助教 2007 – 2010: University of Tokyo, University Hospital, Assistant professor 2005 – 2006: 東京大学, 医学部附属病院, 助手 2005: 東京大学, 医学部附属病院内科, 助手 Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Metabolomics / Endocrinology / Basic Section 54040:Metabolism and endocrinology-related / Basic Section 42020:Veterinary medical science-related
Keywords	Principal Investigator 糖尿病 / インスリンシグナル伝達系 / ペプチド / 糖脂質代謝 / 肥満 / グレリン / インスリン抵抗性 / LEAP2 / 生理活性ペプチド / 臓器連関 … More / エネルギー・糖質代謝異常 / 炎症 / 自律神経 / 摂食中枢 / mTOR / 糖質代謝異常 / エネルギー / シグナル伝達 … More Except Principal Investigator インスリン / 糖尿病 / Pin1 / 肥満 / 代謝 / インスリン分泌 / プロリン異性化酵素 / メタボリックシンドローム / シグナル伝達 / グルコーストランスポーター / 糖代謝 / TFG / ペプチド / インスリン抵抗性 / 糖取り込み / プロテオミクス / 脂肪細胞 / 代謝異常 / Hippoシグナル / 線維化 / 炎症 / 糖代謝異常 / 受容体 / 迷走神経 / メタボシックシンドローム / LUBAC / 肝細胞 / 内分泌学 / ペプチドホルモン / 糖脂質代謝 / 摂食中枢 / 生理活性ペプチド / 糖・脂質代謝 / ＴＦＧ / キサンチンオキシダーゼ / 尿酸 / 生活習慣病 / insulin resistance / IRS-1 / glucose transporter / proteomics / Diabetes mellitus / insulin / 交感神経 / エネルギー代謝 / 細胞内伝達情報 / 視床下部 / 摂食調節 / 分子血管病態 / Relmβ / 自然免疫 / マクロファージ / NASH モデル / インスリン作用 / 脂肪細胞分化 / 脂肪肝 / 糖の取り込み Less

Hippo/YAP経路へのPin1作用と肝や脂肪組織の肥大、炎症、線維化への関与
- Principal Investigator
  
  浅野知一郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Hiroshima University
ニューロメジンUと関連ペプチドによるデクレチン効果と糖尿病病態との関連の解析
- Principal Investigator
  
  張維東
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  University of Miyazaki
Regulatory mechanism of hepatic glucose metabolism by ghrelin and LEAP2Principal Investigator
- Principal Investigator
  
  Sakoda Hideyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  University of Miyazaki
Identify the novel bioactive peptides and their role in feeding regulation
- Principal Investigator
  
  Nakazato Masamitsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  University of Miyazaki
The mechanism of high fat diet induced neural inflammation and obesePrincipal Investigator
- Principal Investigator
  
  Sakoda Hideyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Miyazaki
Roles of trk-fused gene product protein
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Roles of Pin1 and PAR 14 on the metabolic regulations
- Principal Investigator
  
  Asano Tomoichiro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Detection and functional analysis of the novel peptides regulating feeding and energy metabolic homeostasis
- Principal Investigator
  
  Nakazato Masamitsu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Endocrinology
- Research Institution
  University of Miyazaki
Elucidation of pathogenesis of the onset of lifestyle-related diseases due to oxidative stress derived from diet components
- Principal Investigator
  
  Kushiyama Akifumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
Role of a novel LST8-binding protein on mTOR signal and glucose and lipid metabolismPrincipal Investigator
- Principal Investigator
  
  SAKODA Hideyuki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Miyazaki
  The University of Tokyo
The role of resistin-like molecules in natural immune system involving insulin resistance.
- Principal Investigator
  
  KUSHIYAMA Akifumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute for Adult Diseases Asahi Life Foundation
Elucidation of the role of Pin1 on the adipose differentiation
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
Elucidation of the molecular mechanisms underlying insulin resistance and metabolic disorders using a proteomics technology
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
The role of TORC signal on impaired glucose tolerance and cloning the new protein binding with TORC.Principal Investigator
- Principal Investigator
  
  SAKODA Hideyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
Elucidation of the molecular mechanisms underlying metabolic disorders using protemomics analysis
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Metabolomics
- Research Institution
  Hiroshima University
小胞構成蛋白の網羅的解析による糖輸送担体の制御機構および糖尿病における障害の解明
- Principal Investigator
  
  ASANO Tomoichiro
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo
レジスチン関連蛋白の生理学的役割の解明と受容体のクローニングPrincipal Investigator
- Principal Investigator
  
  迫田秀之
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

[Journal Article] Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines2023
- Author(s)
  Kanna, M; Nakatsu, Y ; Yamamotoya, T, Takeshi ; Kushiyama, A ; Fujishiro, M ; Sakoda, H ; Ono, H ; Arihiro, K ; Asano, T
- Journal Title
  
  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
  
  Volume: 24 Issue: 10 Pages: 8847-8847
- DOI
  10.3390/ijms24108847
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08077, KAKENHI-PROJECT-22K08655, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-23K27650
[Journal Article] The NERP-4-SNAT2 axis regulates pancreatic β-cell maintenance and function2023
- Author(s)
  Zhang Weidong、Miura Ayako、Abu Saleh Md Moin、Shimizu Koichiro、Mita Yuichiro、Tanida Ryota、Hirako Satoshi、Shioda Seiji、Gmyr Valery、Kerr-Conte Julie、Pattou Francois、Jin Chunhuan、Kanai Yoshikatsu、Sasaki Kazuki、Minamino Naoto、Sakoda Hideyuki、Nakazato Masamitsu
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 1-21
- DOI
  10.1038/s41467-023-43976-8
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K19451, KAKENHI-PROJECT-21K11632, KAKENHI-PROJECT-22K06004, KAKENHI-PROJECT-22K06606, KAKENHI-PROJECT-22K19404, KAKENHI-PUBLICLY-22H05579, KAKENHI-PROJECT-23K24071, KAKENHI-PROJECT-23K24437
[Journal Article] Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells2023
- Author(s)
  Akasaka Y, Hasei S, Ohata Y, Kanna M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Ono H, Matsubara A, Hinata N, Asano T, Yamamotoya T.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 24(21) Issue: 21 Pages: 16011-16011
- DOI
  10.3390/ijms242116011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08580, KAKENHI-PROJECT-22K08655, KAKENHI-PROJECT-19K02314, KAKENHI-PROJECT-21K08570, KAKENHI-PROJECT-23K27650
[Journal Article] Liver-Expressed Antimicrobial Peptide 2 is a Hepatokine that Predicts Weight Loss and Complete Remission of Type 2 Diabetes Mellitus After Vertical Sleeve Gastrectomy in Japanese Individuals.2023
- Author(s)
  Nabekura H, Islam MN, Sakoda H, Yamaguchi T, Saiki A, Nabekura T, Oshiro T, Tanaka Y, Murayama S, Zhang W, Tatsuno I, Nakazato M.
- Journal Title
  
  Obesity Facts
  
  Volume: - Issue: 4 Pages: 392-400
- DOI
  10.1159/000530733
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08911
[Journal Article] Liver-expressed antimicrobial peptide 2 functions independently of growth hormone secretagogue receptor in calorie-restricted mice2022
- Author(s)
  Islam Md Nurul、Zhang Weidong、Sakai Katsuya、Nakazato Yuki、Tanida Ryota、Sakoda Hideyuki、Takei Toshiki、Takao Toshifumi、Nakazato Masamitsu
- Journal Title
  
  Peptides
  
  Volume: 151 Pages: 170763-170763
- DOI
  10.1016/j.peptides.2022.170763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08911
[Journal Article] Human liver‐expressed antimicrobial peptide 2 elevation in the cerebrospinal fluid in bacterial meningitis2021
- Author(s)
  Sakai Katsuya、Shiomi Kazutaka、Mochizuki Hitoshi、Islam Md Nurul、Nabekura Hiroki、Tanida Ryota、Sakoda Hideyuki、Nakazato Masamitsu
- Journal Title
  
  Brain and Behavior
  
  Volume: 1 Issue: 5
- DOI
  10.1002/brb3.2111
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10052, KAKENHI-PROJECT-18K19551, KAKENHI-PROJECT-20K08911
[Journal Article] Impaired adaptation of energy intake induces severe obesity in aged mice on a high-fat diet2019
- Author(s)
  Okada Tadashi、Mita Yuichiro、Sakoda Hideyuki、Nakazato Masamitsu
- Journal Title
  
  Physiological Reports
  
  Volume: 7 Issue: 3 Pages: e13989-e13989
- DOI
  10.14814/phy2.13989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K18707, KAKENHI-PROJECT-18K19551
[Journal Article] Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation2019
- Author(s)
  Ueda Koji、Nakatsu Yusuke、Yamamotoya Takeshi、Ono Hiraku、Inoue Yuki、Inoue Masa-Ki、Mizuno Yu、Matsunaga Yasuka、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Takahashi Shin-Ichiro、Matsubara Akio、Asano Tomoichiro
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 17 Pages: 1637-1648
- DOI
  10.18632/oncotarget.26691
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-25221204
[Journal Article] Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.2019
- Author(s)
  Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.
- Journal Title
  
  Cell Rep.
  
  Volume: 26 Issue: 12 Pages: 3221-3230
- DOI
  10.1016/j.celrep.2019.02.066
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K11670, KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-18H03972, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16H06226, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-16K11503, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-19K17951, KAKENHI-PROJECT-17H01565, KAKENHI-PROJECT-18H02859, KAKENHI-PROJECT-17K11644
[Journal Article] Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications2018
- Author(s)
  Okubo Hirofumi、Kushiyama Akifumi、Nakatsu Yusuke、Yamamotoya Takeshi、Matsunaga Yasuka、Fujishiro Midori、Sakoda Hideyuki、Ohno Haruya、Yoneda Masayasu、Asano Tomoichiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 10 Pages: 3064-3064
- DOI
  10.3390/ijms19103064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model2018
- Author(s)
  Inoue Masa-Ki、Yamamotoya Takeshi、Nakatsu Yusuke、Ueda Koji、Inoue Yuki、Matsunaga Yasuka、Sakoda Hideyuki、Fujishiro Midori、Ono Hiraku、Morii Kenichi、Sasaki Kensuke、Masaki Takao、Suzuki Yusuke、Asano Tomoichiro、Kushiyama Akifumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 12 Pages: 3967-3967
- DOI
  10.3390/ijms19123967
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08502, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages2018
- Author(s)
  Yamazaki Hiroki、Kushiyama Akifumi、Sakoda Hideyuki、Fujishiro Midori、Yamamotoya Takeshi、Nakatsu Yusuke、Kikuchi Takako、Kaneko Sunao、Tanaka Hirotoshi、Asano Tomoichiro
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2018 Pages: 1-12
- DOI
  10.1155/2018/3062319
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18KT0017, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-17K16158, KAKENHI-PROJECT-16H05330, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09791
[Journal Article] Analysis of peripheral ghrelin signaling via the vagus nerve in ghrelin receptor?restored GHSR-null mice2018
- Author(s)
  Okada Tadashi、Waise T.M. Zaved、Toshinai Koji、Mita Yuichiro、Sakoda Hideyuki、Nakazato Masamitsu
- Journal Title
  
  Neuroscience Letters
  
  Volume: 681 Pages: 50-55
- DOI
  10.1016/j.neulet.2018.05.035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19551, KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K18707
[Journal Article] Restoration of metabolic inflammation-related ghrelin resistance by weight loss.2018
- Author(s)
  Naznin F, Toshinai K, Waise TZ, Okada T, Sakoda H, Nakazato M.
- Journal Title
  
  J Mol Endocrinol.
  
  Volume: 60 Issue: 2 Pages: 109-118
- DOI
  10.1530/jme-17-0192
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16H05333
[Journal Article] Clinical application of ghrelin for diabetic peripheral neuropathy2017
- Author(s)
  Ueno H, Shiiya T, Nagamine K, Tsuchimochi W, Sakoda H, Shiomi K, Kangawa K, Nakazato M.
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: Suppl. Pages: S53-S57
- DOI
  10.1507/endocrj.64.S53
- NAID
  130007307939
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05333
[Journal Article] Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.2017
- Author(s)
  Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 1-13
- DOI
  10.1038/s41598-017-13432-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-16K09784, KAKENHI-PROJECT-16K09791, KAKENHI-PROJECT-17K09850, KAKENHI-PROJECT-17K16150, KAKENHI-PROJECT-16J09463, KAKENHI-PROJECT-15K09398
[Journal Article] Neuromedin U suppresses glucose-stimulated insulin secretion in pancreatic β cells.2017
- Author(s)
  Zhang W, Sakoda H, Miura A, Shimizu K, Mori K, Miyazato M, Takayama K, Hayashi Y, Nakazato M.: Neuromedin U
- Journal Title
  
  Biochem Biophys Res Commun,
  
  Volume: 493 Issue: 1 Pages: 677-683
- DOI
  10.1016/j.bbrc.2017.08.132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-17K16051, KAKENHI-PROJECT-15H04658, KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-15K09445
[Journal Article] Reduced SHARPIN and LUBAC Formation May Contribute to CCl4- or Acetaminophen-Induced Liver Cirrhosis in Mice.2017
- Author(s)
  Yamamotoya, T., Nakatsu, Y., Matsunaga, Y., Fukushima, T., Yamazaki, H., Kaneko, S., Fujishiro, M., Kikuchi, T., Kushiyama, A., Tokunaga, F., Asano, T., Sakoda, H.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 18 Pages: 326-326
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] NERP-2 regulates gastric acid secretion and gastric emptying via the orexin pathway.2017
- Author(s)
  Cherl Namkoong, Koji Toshinai, Zaved Waise, Hideyuki Sakoda, Kazuki Sasaki, Yoichi Ueta, Min-Seon Kim, Naoto Minamino, Masamitsu Nakazato.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 485 Issue: 2 Pages: 409-413
- DOI
  10.1016/j.bbrc.2017.02.064
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-26560368, KAKENHI-PROJECT-16K09404, KAKENHI-PROJECT-16K09761
[Journal Article] Involvement of Resistin-like molecule beta in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice2016
- Author(s)
  Okubo H., Kushiyama, A., Sakoda, H., Nakatsu, Y., Iizuka, M., Taki, N., Fujishiro, M., Fukushima, T., Kamata, H., Nagamachi, A., Inaba, T., Nishimura, F., Katagiri, H., Asahara, T., Yoshida, Y., Chonan, O., Encinas, J., and Asano, T.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 20157-20157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.2016
- Author(s)
  Nakatsu, Y., Matsunaga, Y., Yamamotoya, T., Ueda, K., Inoue, Y., Mori, K., Sakoda, H., Fujishiro, M., Ono, H., Kushiyama, A., and Asano, T.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Role of uric acid metabolism-related inflammation in the pathogenesis of metabolic syndrome components such as atherosclerosis and non-alcoholic steatohepatitis2016
- Author(s)
  Kushiyama, A., Nakatasu, Y., Matsunaga, Y., Yamamotoya, T., Mori, K., Ueda, K., Sakoda, H., Fujishiro, M., Ono, H., and Asano, T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2016 Pages: 8603164-8603164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Canagliflozin, a sodium glucose cotransporter 2 inhibitor, attenuates obesity-induced inflammation in the nodose ganglion, hypothalamus, and skeletal muscle of mice2016
- Author(s)
  Naznin F, Sakoda H, Okada T, Tsubouchi H, Waise TM, Arakawa K, Nakazato M
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 794 Pages: 37-44
- DOI
  10.1016/j.ejphar.2016.11.028
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05333, KAKENHI-PROJECT-16K09761, KAKENHI-PROJECT-15K19424
[Journal Article] Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.2016
- Author(s)
  Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 20157-20157
- DOI
  10.1038/srep20157
- NAID
  120006796541
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26860735, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-16K09791
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Tsuchiya, Y., Kamata, H., Nishimutra, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Endocrinol Metab.
  
  Volume: 309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu, Y., Seno, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Katasako, A., Mori, K., Matsunaga, Y., Fukushima, T., Kanaoka, R., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.2015
- Author(s)
  Qiang S, Nakatsu Y, Seno Y, Fujishiro M, Sakoda H, Kushiyama A, Mori K, Matsunaga Y, Yamamotoya T, Kamata H, Asano T.
- Journal Title
  
  Diabetol Metab Syndr.
  
  Volume: 7 Issue: 1 Pages: 104-104
- DOI
  10.1186/s13098-015-0102-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461372
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Tsuchiya, Y., Kamata, H., Nishimutra, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Endocrinol Metab.
  
  Volume: 309
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 50-50
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Akifumi Kushiyama, Midori Fujishiro, Toshiaki Fukushima, Yasuka Matsunaga, Haruya Ohno, Masayasu Yoneda, Hideaki Kamata, Takanori Shinjo, Misaki Iwashita, Fusanori Nishimura, and Tomoichiro Asano
- Journal Title
  
  Am. J. Physiol. Gastrointest. Liver Physiol.
  
  Volume: 308 Issue: 2 Pages: 151-158
- DOI
  10.1152/ajpgi.00198.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406
[Journal Article] Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.2015
- Author(s)
  Qiang, S., Nakatsu, Y., Seno, Y., Fujishiro, M., Sakoda, H., Kushiyama, A., Mori, K., Matsunaga, Y., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 104-104
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Effects of miglitol, acarbose, and sitagliptin on plasma insulin and gut peptides in type 2 diabetes mellitus: A crossover study2015
- Author(s)
  Ueno H, Tsuchimochi W, Wang HW, Yamashita E, Tsubouchi C, Nagamine K, Sakoda H, Nakazato M
- Journal Title
  
  Diabetes Ther
  
  Volume: 6 Issue: 2 Pages: 187-196
- DOI
  10.1007/s13300-015-0113-3
- Open Access
- Data Source
  KAKENHI-PROJECT-25293216
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu Y, Seno Y, Kushiyama A, Sakoda H, Fujishiro M, Katasako A, Mori K, Matsunaga Y, Fukushima T, Kanaoka R, Yamamotoya T, Kamata H, Asano T.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
  
  Volume: 309(1) Issue: 1 Pages: G42-G51
- DOI
  10.1152/ajpgi.00443.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.2015
- Author(s)
  Nakatsu, Y., Seno, Y., Kushiyama, A., Sakoda, H., Fujishiro, M., Katasako, A., Mori, K., Matsunaga, Y., Fukushima, T., Kanaoka, R., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Prolyl Isomerase Pin1 Negatively Regulates AMPK by Associating with the CBS Domain in the γ-subunit.2015
- Author(s)
  Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, T., Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 24255-24266
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Okubo, H., Nakatsu, Y., Sakoda, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Matsunaga, Y., Ohno, H., Yoneda, M., Kamata, H., Shinjo, T., Iwashita, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 308
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka R, Kushiyama A, Seno Y, Nakatsu Y, Matsunaga Y, Fukushima T, Tsuchiya Y, Sakoda H, Fujishiro M, Yamamotoya T, Kamata H, Matsubara A, Asano T.
- Journal Title
  
  PLoS One.
  
  Volume: 10 (6) Issue: 6 Pages: e0127467-e0127467
- DOI
  10.1371/journal.pone.0127467
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10591, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Diet-induced obesity causes peripheral and central ghrelin resistance by promoting inflammation2015
- Author(s)
  Naznin F, Toshinai K, Waise TM, NamKoong C, Md Moin AS, Sakoda H, Nakazato M
- Journal Title
  
  J Endocrinol
  
  Volume: 226 Issue: 1 Pages: 81-92
- DOI
  10.1530/joe-15-0139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26560368, KAKENHI-PROJECT-25293216
[Journal Article] Teneligliptin improves glycemic control with the reduction of postprandial insulin requirement in Japanese diabetic patients2015
- Author(s)
  Tsuchimochi W, Ueno H, Yamashita E, Tsubouchi C, Sakoda H, Nakamura S, Nakazato M
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 1 Pages: 13-20
- DOI
  10.1507/endocrj.EJ14-0393
- NAID
  130004690934
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126009, KAKENHI-PROJECT-25293216
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga, Y., Nakatsu, Y., Fukushima, T., Okubo, H., Iwashita, M., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kushiyama, A., Takahashi, S., Tsuchiya, Y., Kamata, H., Tokunaga, F., Iwai, K., and Asano, T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 12 Pages: 125380-125380
- NAID
  120005745641
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice2015
- Author(s)
  Ｓhinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Nishimura F, Asano T.
- Journal Title
  
  Diabetol Metab Syndr
  
  Volume: ７ Issue: 1 Pages: 50-50
- DOI
  10.1186/s13098-015-0047-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15351, KAKENHI-PROJECT-25461372
[Journal Article] Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.2015
- Author(s)
  Qiang, S., Nakatsu, Y., Seno, Y., Fujishiro, M., Sakoda, H., Kushiyama, A., Mori, K., Matsunaga, Y., Yamamotoya, T., Kamata, H., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 104-104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga, Y., Nakatsu, Y., Fukushima, T., Okubo, H., Iwashita, M., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kushiyama, A., Takahashi, S., Tsuchiya, Y., Kamata, H., Tokunaga, F., Iwai, K., and Asano, T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 12 Pages: 125380-125380
- NAID
  120005745641
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Ghrelin Administration for Chronic Respiratory Failure: A Randomized Dose-Comparison Trial. Lung2015
- Author(s)
  Matsumoto N, Miki K, Tsubouchi H, Sakamoto A, Arimura Y, Yanagi S, Iiboshi H, Yoshida M, Souma R, Ishimoto H, Yamamoto Y, Yatera K, Yoshikawa M, Sagara H, Iwanaga T, Mukae H, Maekura R, Kimura H, Nakazato M, Kangawa K
- Journal Title
  
  Lung
  
  Volume: 193 Issue: 2 Pages: 239-247
- DOI
  10.1007/s00408-015-9685-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22126002, KAKENHI-PLANNED-22126009, KAKENHI-PROJECT-25293216, KAKENHI-PROJECT-26670419, KAKENHI-PROJECT-24591133
[Journal Article] Prolyl Isomerase Pin1 Negatively Regulates AMPK by Associating with the CBS Domain in the γ-subunit.2015
- Author(s)
  Nakatsu, Y., Iwashita, M., Sakoda, H., Ono, H., Nagata, K., Matsunaga, Y., Fukushima, T., Fujishiro, M., Kushiyama, A., Kamata, H., Takahashi, S., Katagiri, H., Honda, H., Kiyonari, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 290 Pages: 24255-24266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.2015
- Author(s)
  Matsunaga Y, Nakatsu Y, Fukushima T, Okubo H, Iwashita M, Sakoda H, Fujishiro M, Yamamotoya T, Kushiyama A, Takahashi S, Tsuchiya Y, Kamata H, Tokunaga F, Iwai K, Asano T.
- Journal Title
  
  Mediators Inflamm.
  
  Volume: 2015 Issue: 1 Pages: 125380-125380
- DOI
  10.1155/2015/125380
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08259, KAKENHI-PROJECT-26460369, KAKENHI-PUBLICLY-15H01172, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-15H04694, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670154, KAKENHI-PLANNED-24112002, KAKENHI-PROJECT-25221204, KAKENHI-PROJECT-25253019
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka, R., Kushiyama, A., Seno, Y., Nakatsu, Y., Matsunaga, Y., Fukushima, T., Tsuchiya, Y., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kamata, H., Matsubara, A., and Asano, T.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.2015
- Author(s)
  Kanaoka, R., Kushiyama, A., Seno, Y., Nakatsu, Y., Matsunaga, Y., Fukushima, T., Tsuchiya, Y., Sakoda, H., Fujishiro, M., Yamamotoya, T., Kamata, H., Matsubara, A., and Asano, T.
- Journal Title
  
  PLoS One.
  
  Volume: 10
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice.2015
- Author(s)
  Shinjo, T., Nakatsu, Y., Iwashita, M., Sano, T., Sakoda, H., Ishihara, H., Kushiyama, A., Fujishiro, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Diabetol. Metab. Syndr.
  
  Volume: 7 Pages: 50-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26670451
[Journal Article] DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.2015
- Author(s)
  Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Am J Physiol Endocrinol Metab.
  
  Volume: 309(3) Issue: 3 Pages: E214-E223
- DOI
  10.1152/ajpendo.00553.2014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-15K15351, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25461372
[Journal Article] Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit2015
- Author(s)
  Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 40 Pages: 24255-24266
- DOI
  10.1074/jbc.m115.658559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09398, KAKENHI-PROJECT-26460369, KAKENHI-PROJECT-26660287, KAKENHI-PUBLICLY-15H01382, KAKENHI-PUBLICLY-15H01406, KAKENHI-PROJECT-25253067, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26670447, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05220
[Journal Article] One-day high-fat diet induces inflammation in the nodose ganglion and hypothalamus of mice2015
- Author(s)
  Waise TM, Toshinai K, Naznin F, NamKoong C, Md Moin AS, Sakoda H, Nakazato M
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 464 Issue: 4 Pages: 1157-1162
- DOI
  10.1016/j.bbrc.2015.07.097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26560368, KAKENHI-PROJECT-25293216
[Journal Article] Mosapride citrate improves nonalcoholic steatohepatitis with increased fecal lactic acid bacteria and plasma glucagon-like peptide-1 level in a rodent model.2015
- Author(s)
  Okubo, H., Nakatsu, Y., Sakoda, H., Kushiyama, A., Fujishiro, M., Fukushima, T., Matsunaga, Y., Ohno, H., Yoneda, M., Kamata, H., Shinjo, T., Iwashita, M., Nishimura, F., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Gastrointest Liver Physiol.
  
  Volume: 308
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26293219
[Journal Article] Valsartan restores inflammatory response by macrophages in adipose and hepatic tissues of LPS-infused mice2013
- Author(s)
  Iwashita M, Nakatsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima T, Kumamoto S, Shinjo T, Kamata H, Nishimura F, Asano T
- Journal Title
  
  Adipocyte
  
  Volume: 2(1) Issue: 1 Pages: 28-32
- DOI
  10.4161/adip.21837
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24792328
[Journal Article] Integrator complex plays anessential role inadipose differentiation2013
- Author(s)
  Otani Y, Nakatsu Y, Sakoda H, Fukushima T, Fujishiro M, Kushiyama A, Okubo H, Tsuchiya Y, Ohno H, Takahashi S, Nishimura F, Kamata H, Katagiri H, Asano T.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 434 Issue: 2 Pages: 197-202
- DOI
  10.1016/j.bbrc.2013.03.029
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928
[Journal Article] Lactobacillus casei strain Shirota protects against non-alcoholic steatohepatitis development in a rodent model2013
- Author(s)
  Okubo H, Sakoda H, Kushiyama A, Fujishiro M, Nakatsu Y, Fukushima T, Matsunaga Y, Kamata H, Asahara T, Yoshida Y, Chonan O, Iwashita M, Nishimura F, Asano T
- Journal Title
  
  American Journal Physiolgy-Gastrointestinal and Liver Physiogy
  
  Volume: 305 Issue: 12 Pages: 911-918
- DOI
  10.1152/ajpgi.00225.2013
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Par14 associates with IRS-1, thereby enhancing insulin-induced IRS-1 phosphorylation and metabolic actions.2013
- Author(s)
  Zhang J, Nakatsu Y, Sinjo T, Guo Y, Sakoda H, Yamamotoya T, Otani Y, Okubo H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T.
- Journal Title
  
  Ｊournal of Biological Chemistry
  
  Volume: 288 Issue: 28 Pages: 20692-20701
- DOI
  10.1074/jbc.m113.485730
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PROJECT-25461372
[Journal Article] Resistin-Like Molecule β Is Abundantly Expressed in Foam Cells and Is Involved in Atherosclerosis Development.2013
- Author(s)
  Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T.
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 33 Issue: 8 Pages: 1986-1993
- DOI
  10.1161/atvbaha.113.301546
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23591099, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24657092, KAKENHI-PROJECT-24790928, KAKENHI-PUBLICLY-25111705, KAKENHI-PROJECT-25460416, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-25670762
[Journal Article] Xanthine oxidoreductase is involved in macrophage foam cell formation and atherosclerosis development2012
- Author(s)
  Kushiyama, A., Okubo, H., Zhang, J., Sakoda, H., Kikuchi, T., Fujishiro, M., Sato, H., Kushiyama, S., Iwashita, M., Nishimura, F., Fukushima, T., Nakatsu, Y., Kamata, H., Kurihara, H., Kikuchi, M., Kawazu, S., and Asano, T.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Pages: 291-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] Xanthine Oxidoreductase Is Involved in Macrophage Foam Cell Formation and atherosclerosis development2012
- Author(s)
  Kushiyama A, Okubo H, Sakoda H, Kikuchi T, Fujishiro M, Sato H, Kushiyama S, Iwashita M, Nishimura F, Fukushima T, Nakatsu Y, Kamata H, Kawazu S, Higashi Y, Kurihara H, Asano T.
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 32 Issue: 2 Pages: 291-298
- DOI
  10.1161/atvbaha.111.234559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390238, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24790928
[Journal Article] Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.2012
- Author(s)
  Iwashita M, Sakoda H, Kushiyama A, Fujishiro M, Ohno H, Nakatsu Y, Fukushima T, Kumamoto S, Tsuchiya Y, Kikuchi T, Kurihara H, Akazawa H, Komuro I, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  American Journal of Physiology - Endocrinology and Metabolism
  
  Volume: 302 Issue: 3 Pages: 286-296
- DOI
  10.1152/ajpendo.00324.2011
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20117012, KAKENHI-PROJECT-21390556, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23390213, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24790928
[Journal Article] Valsartan, independently of AT1 receptor or PPAR・2012
- Author(s)
  Iwasita, M., Sakoda, H., Kushiyama, A., Fujishiro, M., Ohno, H., Nakatsu, Y., Fukushima, T., Kumamoto, S., Tsuchiya, Y., Kikuchi, T., Kurihara, H., Akazawa, H., Komuro, I., Kamata, H., Nishimura, F. and Asano, T.
- Journal Title
  
  suppresses LPS-induced macrophage activation and improves insulin resistance in co-cultured adipocytes Am. J. Physiol. Cell Physiol.
  
  Volume: 302 Pages: 286-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] Role of Pin1 in the pathogenesis of non-alcoholic steatohepatitis in a rodent model2012
- Author(s)
  Nakatsu Y, Otani Y, Sakoda H, Zhang J, Guo Y, Okubo H, Kushiyama A, Fujishiro M, Kikuchi T, Fukushima T, Ohno H, Tsuchiya Y, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Issue: 53 Pages: 44526-44535
- DOI
  10.1074/jbc.m112.397133
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PUBLICLY-23013007, KAKENHI-PROJECT-23370062, KAKENHI-PROJECT-23659107, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022, KAKENHI-PROJECT-24249047, KAKENHI-PROJECT-24591314, KAKENHI-PROJECT-24591315, KAKENHI-PROJECT-24790928
[Journal Article] LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST8 Obesity Res Clin Pract2012
- Author(s)
  Kikuchi, T., Zhang, J., Sakoda, H., Koketsu, Y., Fujishiro, M., Kushiyama, A., Nakatsu, Y., Kamata, H., Inoki, K., Takahashi, S., Kurihara, H., Katagiri, H., Oka, Y., and Asano, T.
- Volume
  in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] Peptidyl-prolyl Cis/Trans Isomerase NIMA-interacting 1 Associates with Insulin Receptor Substrate-1 and Enhances Insulin Actions and Adipogenesis2011
- Author(s)
  Nakatsu, Y., Sakoda, H., Asano T., et al.
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 286 Pages: 20812-20822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] mTORシグナルと糖脂質代謝異常2011
- Author(s)
  迫田秀之, 浅野知一郎
- Journal Title
  
  実験医学 29(6)
  
  Pages: 895-899
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis.2011
- Author(s)
  Nakatsu Y, Sakoda H, Kushiyama A, Zhang J, Ono H, Fujishiro M, Kikuchi T, Fukushima T, Yoneda M, Ohno H, Horike N, Kanna M, Tsuchiya Y, Kamata H, Nishimura F, Isobe T, Ogihara T, Katagiri H, Oka Y, Takahashi SI, Kurihara H, Uchida T, Asano T.
- Journal Title
  
  J Biol Chem 286(23)
  
  Pages: 20812-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity.2011
- Author(s)
  Ohno H, sakoda h, et.al
- Journal Title
  
  Am J Physiol Cell Physiol.
  
  Volume: (掲載確定,印刷中掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with IRS-1 and enhances insulin actions and adipogenesis2011
- Author(s)
  Nakatsu Y, Sakoda H, Kushiyama A, Zhang J, Ono H, Fujishiro M, Kikuchi T, Fukushima T, Yoneda M, Ohno H, Horike N, Kanna M, Tsuchiya Y, Kamata H, Nishimura F, Isobe T, Ogihara T, Katagiri H, Oka Y, Takahashi SI, Kurihara H, Uchida T, Asano T
- Journal Title
  
  J Biol Chem
  
  Volume: 286 Issue: 23 Pages: 20812-20822
- DOI
  10.1074/jbc.m110.206904
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390556, KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-22248030, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-22790869, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-23791047, KAKENHI-PROJECT-23870022
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity2011
- Author(s)
  Ohno, H., Nakatsu, Y., sakoda, H., Kushiyama, A., Ono, H., Fujishiro, M., Otani, Y., Okubo, H., Yoneda, M., Fukushima, T., Tsuchiya, Y., Kamata, H., Nishimura, F., Kurihara, H., Katagiri, H., Oka, Y., and Asano, T.
- Journal Title
  
  Am. J. Physiol. Cell Physiol
  
  Volume: 300 Pages: 47-54
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity.2011
- Author(s)
  Ohno H, Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Otani Y, Okubo H, Yoneda M, Fukushima T, Kamata H, Nishimura F, Kurihara H, Katagiri H, Oka Y, Asano T.
- Journal Title
  
  Am J Physiol Cell Physiol 300(5)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] 4F2hc stabilizes GLUT1 protein and increases glucose transport activity2011
- Author(s)
  Ohno H, Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Otani Y, Okubo H, Yoneda M, Fukushima T, Kamata H, Nishimura F, Kurihara H, Katagiri H, Oka Y, Asano T
- Journal Title
  
  Am J Physiol Cell Physiol
  
  Volume: 300(5) Issue: 5 Pages: 1047-54
- DOI
  10.1152/ajpcell.00416.2010
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22126006, KAKENHI-PROJECT-22780249, KAKENHI-PROJECT-22790847, KAKENHI-PROJECT-22790869, KAKENHI-PROJECT-23390238, KAKENHI-PROJECT-23791047
[Journal Article] mTORシグナルと糖脂質代謝異常2011
- Author(s)
  迫田秀之、浅野知一郎
- Journal Title
  
  実験医学
  
  Volume: 29(6) Pages: 895-899
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] Peptidyl-prolyl Cis/ Trans Isomerase NIMA-interacting 1 Associates with Insulin Receptor Substrate-1 and Enhances Insulin Actions and Adipogenesis2011
- Author(s)
  Nakatsu, Y., Sakoda, H., Kushiyama, A., Zhang, J., Ono, H., Fujishiro, M., Kikuchi, T., Fukushima, T., Yoneda, M., Ohno, H., Horike, N., Kanna, M., Tsuchiya, Y., Kamata, H., Nishimura, F., Isobe, T., Ogihara, T., Katagiri, H., Oka, Y., Takahashi, S., Kurihara, H., Uchida, T., and Asano, T.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 20812-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659175
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.2010
- Author(s)
  Cui X, Kushiyama A, Yoneda M, Nakatsu Y, Guo Y, Zhang J, Ono H, Kanna M, Sakoda H, Ono H, Kikuchi T, Fujishiro M, Shiomi M, Kamata H, Kurihara H, Kikuchi M, Kawazu S, Nishimura F, Asano T.
- Journal Title
  
  Diabetes Res Clin Pract. 87(1)
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Pin1 associates with and induces translocation of CRT C2 to the cytosol, thereby suppressing CRE transcriptional activity2010
- Author(s)
  Nakatsu Y, sakoda h, et.al
- Journal Title
  
  J Biol Chem
  
  Volume: 285(43) Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.2010
- Author(s)
  Cui X, sakoda h, et.al.
- Journal Title
  
  Diabetes Res Clin Pract 87(1)
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Decreased SIRT1 expression and LKB1 phosphorylation occurs with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase.2010
- Author(s)
  Yoneda, M., Guo, Y., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  Obesity Res Clin Pract. 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Association between Type 1 Diabetes Mellitus and Remitting Seronegative Symmetrical Synovitis with Pitting Edema: A case report.2010
- Author(s)
  Sakoda H, Ito S, Kanda H, Fujishiro M, Osuga J, Tsukamoto K, Ueki K, Kadowaki T.
- Journal Title
  
  Diabetes Res Clin Pract. 91(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Paraquat-induced oxidative stress represses PI 3-kinase activities leading to impaired glucose uptake in 3T3-L1 adipocytes.2010
- Author(s)
  Shibata M.; Hakuno F.; Yamanaka D.; Okajima H.; Fukushima T.; Hasegawa T.; Ogata T.; Toyoshima Y.; Chida K.; Kimura K.; Sakoda H.; Takenaka A.; Asano,T ; Takahashi S.I.
- Journal Title
  
  J Biol Chem. 285(27)
  
  Pages: 20915-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Paraquat-induced oxidative stress represses PI 3-kinase activities leading to impaired glucose uptake in 3T3-L1 adipocytes2010
- Author(s)
  Shibata M, sakoda h, et.al
- Journal Title
  
  J.Biol.Chem.
  
  Volume: 285(27) Pages: 20915-20925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity2010
- Author(s)
  Nakatsu, Y., Sakoda, H., Asano T, et al.
- Journal Title
  
  J.Biol.Chem..
  
  Volume: 43 Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity.2010
- Author(s)
  Nakatsu Y, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Horike N, Yoneda M, Ohno H, Kamata H, Tahara H, Isobe T, Nishimura F, Katagiri H, Oka Y, Fukushima T, Takahashi SI, Kurihara H, Uchida T, Asano T.
- Journal Title
  
  J Biol Chem. 285(43)
  
  Pages: 33018-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Decreased SIRT1 expression and LKB1 phosphorylation occurs with long-term high-fat diet feeding, in addition to AMPK phosphorylation impairment in the early phase.2010
- Author(s)
  Yoneda M, Guo Y, Ono H, Nakatsu Y, Zhang Y, Cui X, Iwashita M, Kumamoto S, Tsuchiya Y, Sakoda H, Fujishiro M, Kushiyama A, Koketsu Y, Kikuchi T, Kamata H, Nishimura F, Asano T.
- Journal Title
  
  Obesity Res Clin Pract 4.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Macrophage foam cell formation is augmented in serum from patients with diabetic angiopathy.2010
- Author(s)
  Cui, X., Kushiyama, A., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  Diabetes.Res.Clin.Pract. 87
  
  Pages: 57-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing CRE transcriptional activity2010
- Author(s)
  Nakatsu, Y., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  J.Biol.Chem. 43
  
  Pages: 33018-33027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Growth Hormone Inhibition of Glucose Uptake in Adipocytes Occurs without Affecting GLUT4 Translocation through an Insulin Receptor Substrate-2-Phosphatidylinositol 3-Kinase-dependent Pathway.2009
- Author(s)
  Sasaki-Suzuki N, Arai K, Ogata T, Kasahara K, Sakoda H, Chida K, Asano T, Pessin JE, Hakuno F, Takahashi S.
- Journal Title
  
  J Biol Chem. 284(10)
  
  Pages: 6061-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] AMPK activation increases phosphorylation of GSK3beta and thereby reduces CRE transcriptional activity and PEPCK-C gene expression in the liver.2008
- Author(s)
  Horike N, Sakoda H, Kushiyama A, Ono H, Fujishiro M, Kamata H, Nishiyama K, Uchijima Y, Kurihara Y, Kurihara H, Asano T.
- Journal Title
  
  J Biol Chem. 283(49)
  
  Pages: 33902-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Long-term Forskolin Stimulation Induces AMPK Activation and Thereby Enhances Tight Junction Formation in Human Placental Trophoblast BeWo Cells.2008
- Author(s)
  Egawa, M., Kamata, H., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  Placenta 29
  
  Pages: 1003-1008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Regulation of gut-derived resistin-like molecule b expression by nutrients2008
- Author(s)
  Fujio, J., Kushiyama, A., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  Diab.Res.Clin.Pract. 79
  
  Pages: 2-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Hepatic overexpression of a dominant negative form of Raptor enhances Akt phosphorylation and restores insulin resistance in K/KAy mice.2008
- Author(s)
  Koketsu, Y., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  Am.J.Physiol.Endo.Metab. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] AMPK activation increases phosphorylation of GSK3beta and thereby reduces CRE transcriptional activity and PEPCK-C gene expression in the liver.2008
- Author(s)
  Horike, N., Sakoda, H., Asano, T, et al.
- Journal Title
  
  J. Biol. Chem 283
  
  Pages: 33902-10
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390271
[Journal Article] AMPK activation increases phosphorylation of GSK3beta and thereby reduces CRE transcriptional activity and PEPCK-C gene expression in the liver2008
- Author(s)
  Horike, N., Sakoda, H., Asano, T., et al.
- Journal Title
  
  J.Biol.Chem 283
  
  Pages: 33902-33910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] AMPK activation increases phosphorylation of GSK3beta and thereby reduces CRE transcriptional activity and PEPCK-C gene expression in the liver.2008
- Author(s)
  Horike, N., Sakoda, H., Fujishiro M., Asano, T.
- Journal Title
  
  J.Biol.Chem 283
  
  Pages: 33902-33910
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats.2008
- Author(s)
  Ono H, Pocai A, Wang Y, Sakoda H, Asano T, Backer JM, Schwartz GJ, Rossetti L.
- Journal Title
  
  J Clin Invest. 118(8)
  
  Pages: 2959-68
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Hepatic overexpression of a dominant negative form of Raptor enhances Akt phosphorylation and restores insulin resistance in K/KAy mice2008
- Author(s)
  Koketsu, Y., Sakoda, H., Asano, T., et al.
- Journal Title
  
  Am.J.Physiol.Endo.Metab. 294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390258
[Journal Article] Hepatic overexpression of a dominant negative form of raptor enhances Akt phosphorylation and restores insulin sensitivity in K/KAy mice.2008
- Author(s)
  Koketsu Y, Sakoda H, Fujishiro M, Kushiyama A, Fukushima Y, Ono H, Anai M, Kikuchi T, Fukuda T, Kamata H, Horike N, Uchijima Y, Kurihara H, Asano T.
- Journal Title
  
  Am J Physiol Endocrinol Metab. 294(4)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Long-term Forskolin Stimulation Induces AMPK Activation and Thereby Enhances Tight Junction Formation in Human Placental Trophoblast BeWo Cells.2008
- Author(s)
  Egawa M, Kudo Y, Kamata H, Kushiyama A, Sakoda H, Fujishiro M, Horike N, Yoneda M, Nakatsu Y, Ying G, Jun Z, Tsuchiya Y, Takata K, Kurihara H, Asano T.
- Journal Title
  
  Placenta. 29(12)
  
  Pages: 1003-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591050
[Journal Article] Hepatic overexpression of a dominant negative form of Raptor enhances Akt phosphorylation and restores insulin resistance in K/KAy mice.2008
- Author(s)
  Koketsu, Y., Sakoda, H., Asano, T, et al.
- Journal Title
  
  Am. J. Physiol. Endo. Metab 294
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390271
[Journal Article] Carboxyl-terminal Modulator Protein (CTMP) Induces Akt phosphorylation and activation, therby enhancing anti-apoptotic, glycogen synthetic and glucose uptake pathways.2007
- Author(s)
  Ono, H., Sakoda, H., Asano, T, et. al.
- Journal Title
  
  Am. J. Physiol. Cell. Physiol. 293
  
  Pages: 1576-1585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390271
[Journal Article] Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion. Roles of AMP-Activated Protein Kinase and Beclin 1 in Mediating Autophagy2007
- Author(s)
  Matsui Y, Sakoda H, et al.
- Journal Title
  
  Circ Res. 100(6)
  
  Pages: 914-922
- Data Source
  KAKENHI-PROJECT-17790602
[Journal Article] Physiological significance of resistin and resistin-like molecules in the imflammatory process and insulin resistance2006
- Author(s)
  Asano, T., Sakoda, H., Fujishiro, M., et al.
- Journal Title
  
  Current Diabetes Reviews 2
  
  Pages: 449-454
- Data Source
  KAKENHI-PROJECT-18390271
[Journal Article] Physiological significance of resistin and resistin-like molecules in the inflammatory process and insulin resistance.2006
- Author(s)
  Asano T, Sakoda H, et al.
- Journal Title
  
  Current Diabetes Reviews 2
  
  Pages: 449-454
- Data Source
  KAKENHI-PROJECT-17790602
[Journal Article] Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression.2006
- Author(s)
  Viana, AY., Sakoda, H., Asano, T.et al.
- Journal Title
  
  Diabetes Res Clin Pract. 73
  
  Pages: 135-42
- Data Source
  KAKENHI-PROJECT-18390271
[Journal Article] Role of hepatic AMPK activation in glucose metabolism and dexamethasone-induced regulation of AMPK expression.2006
- Author(s)
  Viana AY, Sakoda H, et al.
- Journal Title
  
  Diabetes Res Clin Pract. 73(2)
  
  Pages: 135-142
- Data Source
  KAKENHI-PROJECT-17790602
[Journal Article] Glycogen debranching enzyme association with β-subunit enhances AMP-activated protein kinase activity2005
- Author(s)
  Sakoda, H., Fujishiro, M., Asano, T., et al.
- Journal Title
  
  Am J Physiol Endocrinol Metab 289(3)
- Data Source
  KAKENHI-PROJECT-17659273
[Presentation] A peptide-amino acid transporter axis regulates pancreatic β-cell maintenance and function2023
- Author(s)
  張維東、迫田秀之、中里雅光
- Organizer
  第34回分子糖尿病シンポジウム
- Data Source
  KAKENHI-PROJECT-22K06004
[Presentation] 摂食、エネルギー代謝と膵β細胞機能を調節するニューロメジンUファミリーペプチドの役割分担の解析2023
- Author(s)
  張維東、迫田秀之、中里雅光
- Organizer
  第66回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-22K06004
[Presentation] A peptide-amino acid transporter axis regulates pancreatic β-cell maintenance and function2023
- Author(s)
  Weidong ZHANG, Julie KERR-CONTE, Francois PATTOU, Naoto MINAMINO, Hideyuki SAKODA, Masamitsu NAKAZATO
- Organizer
  10th Helmholtz Diabetes Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06004
[Presentation] Neuromedin U (NMU) induces β cell failure by triggering mitochondrial dysfunction and ER stress via Gα proteins2022
- Author(s)
  張維東、迫田秀之、三浦綾子、中里雅光
- Organizer
  第６５回日本糖尿病学会
- Data Source
  KAKENHI-PROJECT-22K06004
[Presentation] Interaction between ghrelin and GLP-1 regulates feeding through vagal afferent system2017
- Author(s)
  Hideyuki Sakoda, T M Zaved Waise, Farhana Naznin, Tadashi Okada, Koji Toshinai, Masamitsu Nakazato
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松
- Year and Date
  2017-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-16H05333
[Presentation] Neuromedin U suppressed insulin secretion in β cells2017
- Author(s)
  張維東、迫田秀之、三浦綾子、清水浩一郎、中里雅光
- Organizer
  第31回日本糖尿病肥満動物学会年次学術集会
- Place of Presentation
  横浜市みなとみらい
- Year and Date
  2017-02-10
- Data Source
  KAKENHI-PROJECT-16H05333
[Presentation] 神経を介する炎症波及による摂食調節機構の破綻とインスリン抵抗性2017
- Author(s)
  迫田秀之、ナズニン　ファーハナ、岡田只士、ワイズ・ティーエム　ザベット、十枝内厚次、中里雅光
- Organizer
  第60回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09761
[Presentation] 性ホルモン結合グロブリン（SHBG）による脂肪量減少効果と抗炎症効果2016
- Author(s)
  山崎広貴、櫛山暁史、迫田秀之、藤城緑、山本屋武、菊池貴子、金子直、浅野知一郎
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 高脂肪食による自律神経を介する炎症の波及とグレリン抵抗性の発症2016
- Author(s)
  迫田秀之、十枝内厚次、ナズニン　ファーハナ、ワイズ・ティーエム　ザベット、中里雅光
- Organizer
  第59回日本糖尿病学会年次学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16H05333
[Presentation] Vagal afferent nerve transfer HFD-induced inflammatory signals to the hypothalamus2016
- Author(s)
  T M Zaved Waisea, Koji Toshinai, Farhana Naznin, Cherl NamKoong, Abu Saleh Md Moina, Hideyuki Sakoda, Masamitsu Nakazato
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16H05333
[Presentation] Trk-fused gene（TFG）の膵β細胞における役割の解明2016
- Author(s)
  山本屋武、中津祐介、迫田秀之、藤城緑、山崎広貴、菊池貴子、浅野知一郎、櫛山暁史
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] Diet-induced obesity causes ghrelin resistance by promoting inflammation2016
- Author(s)
  Farhana Naznin, Koji Toshinai, T M Zaved Waise, Cherl NamKoong, Abu Saleh Md Moina, Hideyuki Sakoda, Masamitsu Nakazato
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16H05333
[Presentation] 肝外キサンチンオキシダーゼのインスリン抵抗性への関与2016
- Author(s)
  櫛山暁史、菊池貴子、山崎広貴、迫田秀之、藤城緑、浅野知一郎、岩本安彦
- Organizer
  第59回日本糖尿病学会学術集会
- Place of Presentation
  国立京都国際会議場
- Year and Date
  2016-05-20
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2015
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山本屋武、山崎広貴、中津祐介、浅野知一郎、河津捷二
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討2015
- Author(s)
  松永泰花、中津祐介、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、新城尊徳、岩下未咲、西村英紀、小野啓、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] SGLT2阻害薬ルセオグリフロジンによる非アルコール性脂肪性肝炎の改善作用2015
- Author(s)
  藤城緑、中津祐介、迫田秀之、櫛山暁史、松永泰花、山本屋武、鎌田英明、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 肝臓におけるLUBAC(linear ubiquitin assembly complex)活性低下はAkt-mTOR経路の亢進および肝での炎症を惹起する2015
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、金子直、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 高脂肪食負荷による近位筋優位遺伝性運動感覚ニューロパチー原因遺伝子TFGの発現低下とその病的意義2015
- Author(s)
  浅野知一郎、松永泰花、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、小野啓、中津祐介
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] 性ホルモン結合グルブリン(SHBG)の代謝への影響の検討2015
- Author(s)
  山崎広貴、櫛山暁史、迫田秀之、藤城緑、山本屋武、菊池貴子、金子直、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] DPP4阻害薬anagliptineはLPS投与マウスの肝臓・脂肪組織における炎症反応を抑制する2015
- Author(s)
  新城尊徳、岩下未咲、中津祐介、鎌田英明、迫田秀之、藤城緑、櫛山暁史、浅野知一郎、西村英紀
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] SGLT2阻害薬ルセオグリフロジンによる非アルコール性脂肪性肝炎の改善作用2015
- Author(s)
  藤城緑、中津祐介、迫田秀之、櫛山暁史、松永泰花、山本屋武、鎌田英明、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2015
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山本屋武、山崎広貴、中津祐介、浅野地一郎、河津捷二
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 肝臓におけるLUBAC(linear ubiquitin assembly complex)活性低下はAkt-mTOR経路の亢進および肝での炎症を惹起する2015
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、金子直、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 性ホルモン結合グルブリン(SHBG)の代謝への影響の検討2015
- Author(s)
  山崎広貴、櫛山暁史、迫田秀之、藤城緑、山本屋武、菊池貴子、金子直、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] 高脂肪食負荷による近位筋優位遺伝性運動感覚ニューロパチー原因遺伝子TFGの発現低下とその病的意義2015
- Author(s)
  浅野知一郎、松永泰花、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、小野啓、中津祐介
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] DPP4阻害薬anagliptineはLPS投与マウスの肝臓・脂肪組織における炎症反応を抑制する2015
- Author(s)
  新城尊徳、岩下未咲、中津祐介、鎌田英明、迫田秀之、藤城緑、櫛山暁史、浅野知一郎、西村英紀
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討2015
- Author(s)
  松永泰花、中津祐介、迫田秀之、櫛山暁史、藤城緑、山本屋武、鎌田英明、新城尊徳、岩下未咲、西村英紀、小野啓、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] マクロファージにおける糖代謝による活性酸素産生とインスリン抵抗性2015
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、岩本安彦、浅野知一郎
- Organizer
  第58回日本糖尿病学会学術集会
- Place of Presentation
  山口県
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 膵β細胞機能におけるプロリン異性化酵素Pin1の役割2015
- Author(s)
  中津祐介、森馨一、松永泰花、山本屋武、迫田秀之、藤城緑、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] Novel insights into anti-diabetic effects of sex hormone binding globulin (SHBG): anti-inflammatory actions on both adipocytes and macrophages2015
- Author(s)
  H Yamazaki, A Kushiyama, H Sakoda, M Fujishiro, T Asano
- Organizer
  Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  京都府
- Year and Date
  2015-10-25
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] 膵β細胞機能におけるプロリン異性化酵素Pin1の役割2015
- Author(s)
  中津祐介、森馨一、松永泰花、山本屋武、迫田秀之、藤城緑、櫛山暁史、石原寿光、浅野知一郎
- Organizer
  第５８回日本糖尿病学会年次学術集会
- Place of Presentation
  下関
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] Extrahepatic xanthine oxidoreductase as a therapeutic target for diabetes mellitus and its complications2015
- Author(s)
  A Kushiyama, T Kikuchi, H Yamazaki, H Sakoda, Y Iwamoto, T Asano
- Organizer
  Diabetes: New Insights into Molecular Mechanisms and Therapeutic Strategies Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  京都府
- Year and Date
  2015-10-25
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Involvement of macrophage-derived　resistin like molecule β in atherosclerosis development2013
- Author(s)
  A. Kushiyama, T. Kikuchi, H. Sakoda, M. Fujishiro, K. Nishiyama, H. Kurihara, Y. Higashi, S. Kawazu, T. Asano
- Organizer
  第45回日本動脈硬化学会総会・学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] モサプリドクエン酸塩の3T3-L1脂肪細胞におけるインスリン抵抗性改善作用の解明2011
- Author(s)
  藤城緑、迫田秀之、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] 転写共役因子CRTC3は高脂肪食によって発現誘導され、脂肪細胞分化と肝糖新生を促進する2011
- Author(s)
  浅野知一郎、中津祐介、迫田秀之
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] 非アルコール性脂肪性肝炎(NASH)の発2011
- Author(s)
  迫田秀之、中津祐介、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] 非アルコール性脂肪性肝炎(NASH)の発症におけるプロリン異性化酵素Pin1の役割2011
- Author(s)
  迫田秀之、中津祐介、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] プロリン異性化酵素Pin1類似蛋白Par14/ 17の生理的役割解明2011
- Author(s)
  大野晴也、迫田秀之、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] キサンチンオキシダーゼ経路のマクロファージ泡沫化と動脈硬化への関与2011
- Author(s)
  櫛山暁史、迫田秀之、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] LST8肝過剰発現マウスの糖脂質代謝に与える影響の解析2011
- Author(s)
  菊池貴子、迫田秀之、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] プロリン異性化酵素Pin1類似蛋白Par14/17の生理的役割解明2011
- Author(s)
  大野晴也、迫田秀之、浅野知一郎
- Organizer
  第54回日本糖尿病学会
- Place of Presentation
  札幌
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22659175
[Presentation] Peptidyl prolyl cis/trans isomerase Pin1 interacts with CRTC2 and regulates gluconeogenesis2010
- Author(s)
  中津祐介, 迫田秀之, 浅野知一郎, et al.
- Organizer
  アメリカ糖尿病学会
- Place of Presentation
  Orlando, Florida USA
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] マクロファージより分泌されるレジスチン様分子βの生理的意義とインスリン抵抗性の発症機序2010
- Author(s)
  櫛山暁史、迫田秀之、浅野知一郎, et. al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] LST8 level controls basal p70 S6 kinase and Akt phosphorylations, and mTORC1 and mTORC2 negatively regulate each other by competing for association with LST82010
- Author(s)
  Kikuchi T, Sakoda H, et al.
- Organizer
  第70回アメリカ糖尿病学会学術集会
- Place of Presentation
  Orland, USA
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] LST8によるmTORおよびインスリンシグナル伝達系の調節機構の解明2010
- Author(s)
  菊池貴子、迫田秀之、浅野知一郎, et.al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  岡山
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] LST8によるmTORおよびインスリンシグナルのAktリン酸化への関与2010
- Author(s)
  菊池貴子、迫田秀之、etc.
- Organizer
  日本糖尿病学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] Peptidyl prolyl cis/trans isomerase Pin1 interacts with CRTC2 and regulates gluconeogenesis2010
- Author(s)
  Nakatsu, Y., Sakoda, H., Asano, T., et al.
- Organizer
  メリカ糖尿病学会
- Place of Presentation
  Orlando, Florida USA
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] Involvement of xanthine oxidase pathway in pathogenesis of macrophage activation2010
- Author(s)
  Kushiyama, A., Sakoda H., Asano, T, et al.
- Organizer
  アメリカ糖尿病学会
- Place of Presentation
  Orlando, Florida USA
- Year and Date
  2010-06-27
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] プロリル異性化酵素Pin1はTORC2と結合しCRE活性を抑制することで、肝の糖新生系を制御する2010
- Author(s)
  中津祐介、迫田秀之、浅野知一郎, et. al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] LST8によるmTORおよびインスリンシグナル伝達系の調節機構の解明2010
- Author(s)
  菊池貴子、迫田秀之、浅野知一郎, et. al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] プロリル異性化酵素Pin1はTORC2と結合しCRE活性を抑制することで、肝の糖新生系を制御する2010
- Author(s)
  中津祐介、迫田秀之、浅野知一郎, et.al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  岡山
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] マクロファージより分泌されるレジスチン様分子βの生理的意義とインスリン抵抗性の発症機序2010
- Author(s)
  櫛山暁史、迫田秀之、浅野知一郎, et.al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  岡山
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] 長時間高グルコース刺激による肝細胞インスリン受容体蛋白発現調節および活性調節機構の解明2009
- Author(s)
  藤城緑、迫田秀之、浅野知一郎, et.al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] Impaired mTORc1 Stability Results in LST8 Transfer to mTORc2 and the Enhancement of Akt Phosphorylation in HepG2 Cells2009
- Author(s)
  Kikuchi, T., Sakoda, H., Asano, T., et al.
- Organizer
  アメリカ糖尿病学会
- Place of Presentation
  New Orleans, Louisiana USA
- Year and Date
  2009-06-08
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] 慢性炎症によるインスリン抵抗性の機序2009
- Author(s)
  浅野知一郎、米田真康、大野晴也、櫛山暁史、藤城緑、迫田秀之
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪(シンポジウム)
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] Pin1 binds to IRS-1, and functions as a nutrient-sensing enhancer of insulin signaling2009
- Author(s)
  Nakatsu, Y., Sakoda, H., Asano, T., et al.
- Organizer
  アメリカ糖尿病学会
- Place of Presentation
  New Orleans, Louisiana USA
- Year and Date
  2009-06-07
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] インスリン抵抗性を誘導するレジスチンファミリー分子(resisitin, RELMβ)の動脈硬化への独立した役割の解析2009
- Author(s)
  櫛山暁史、迫田秀之、浅野知一郎, et.al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2009-05-21
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] mTORシグナルのAktリン酸化への関与2009
- Author(s)
  菊池貴子、迫田秀之, etc.
- Organizer
  日本糖尿病学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] mTORシグナルのAktリン酸化への関与2009
- Author(s)
  菊池貴子、迫田秀之、浅野知一郎, et.al.
- Organizer
  日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] Impaired mTORc1 Stability Results in LST8 Transfer to mTORc2 and the Enhancement of Akt Phosphorylation in HepG2 Cells2009
- Author(s)
  菊池貴子, 迫田秀之, et al.
- Organizer
  第69回アメリカ糖尿病学会学術集会
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] 細胞内エネルギー状態とインスリンシグナル伝達系の関連2008
- Author(s)
  福田武俊、迫田秀之、etc.
- Organizer
  日本糖尿病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] Enhancement of Akt phosphorylation in HepG2 by overexpressing C terminally deleted Raptor2008
- Author(s)
  菊池貴子, 迫田秀之, et al.
- Organizer
  第68回アメリカ糖尿病学会学術集会
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] mTORシグナルによるAktリン酸化調整機序の解明2008
- Author(s)
  菊池貴子、迫田秀之, etc.
- Organizer
  日本糖尿病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20591050
[Presentation] 糖尿病モデル動物のインスリン抵抗性におけるmTORシグナルの役割2008
- Author(s)
  纐纈優子, 迫田秀之, 浅野知一郎, 他
- Organizer
  日本糖尿病学会
- Place of Presentation
  日本、仙台
- Year and Date
  2008-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390271
[Presentation] 腸管由来RELM (resistin like molecule)βは動脈硬化・メタボリック症候群に関与する2008
- Author(s)
  櫛山暁史、迫田秀之、浅野知一郎, 他
- Organizer
  日本糖尿病学会
- Place of Presentation
  日本、仙台
- Year and Date
  2008-05-25
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] Roles of mTOR signaling in the insulin resistance of the Diabetic model mice2008
- Author(s)
  Koketsu, Y., Sakoda, H., Asano, T., et al.
- Organizer
  Annual Meeting of Japan Diabetes Society
- Place of Presentation
  Sendai Japan
- Year and Date
  2008-05-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390271
[Presentation] 腸管由来RELM (resistin like molecule)βは動脈硬化・メタボリック症候群に関与する2008
- Author(s)
  櫛山暁史, 迫田秀之, 浅野知一郎, 他
- Organizer
  日本糖尿病学会
- Place of Presentation
  日本、仙台
- Year and Date
  2008-05-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390271
[Presentation] Gut derived RELM (resistin like molecule) β is involved in the Pathogenesis of insulin resistance and atherosclerosis2008
- Author(s)
  Kusiyama, A., Sakoda, H., Asano, T., et al.
- Organizer
  Annual Meeting of Japan Diabetes Society
- Place of Presentation
  Sendai Japan
- Year and Date
  2008-05-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390271
[Presentation] 糖尿病モデル動物のインスリン抵抗性におけるmTORシグナルの役割2008
- Author(s)
  纐纈優子、迫田秀之、浅野知一郎, 他
- Organizer
  日本糖尿病学会
- Place of Presentation
  日本、仙台
- Year and Date
  2008-05-25
- Data Source
  KAKENHI-PROJECT-20390258
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑、中津祐介、福嶋俊明、松永泰花、迫田秀之、櫛山暁史、山本屋武、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] Involvement of Resistin-like molecule β in the development of non-alcoholic steatohepatitis
- Author(s)
  Akifumi Kushiyama, Hirofumi Okubo, Yusuke Nakatsu, Hideyuki Sakoda, Midori Fujishiro, Toshiaki Fukushima, Shin-ichiro Takahashi, Tomoichiro Asano
- Organizer
  第74回米国糖尿病学会議
- Place of Presentation
  米国サンフランシスコ
- Year and Date
  2014-06-13 – 2014-06-17
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] LUBAC (linear ubiquitin chain assembly complex)のインスリンシグナル伝達系における役割の検討
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] マクロファージresistin like moleculeβによるインスリン抵抗性・動脈硬化発症の機序
- Author(s)
  櫛山暁史菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Pin1阻害薬Jugloneを用いたNASH治療効果の検討
- Author(s)
  山崎広貴、中津祐介、鎌田英明、西村英紀、菊池貴子、藤城緑、迫田秀之、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] LUBAC (linear ubiquitin chain assembly complex)のインスリンシグナル伝達系における役割の検討
- Author(s)
  山本屋武、迫田秀之、藤城緑、山崎広貴、菊池貴子、櫛山暁史、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] DPP4阻害薬anagliptinは、活性化マクロファージおよびマクロファージ共培養下脂肪細胞の炎症反応を抑制する
- Author(s)
  新城尊徳、岩下未咲、中津祐介、迫田秀之、藤城緑、櫛山暁史、鎌田英明、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑、中津祐介、福嶋俊明、松永泰花、迫田秀之、櫛山暁史、山本屋武、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] マクロファージresistin like molecule βによるインスリン抵抗性・動脈硬化発症の機序
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] Localization of neuroendocrine regulatory peptide-4 (NERP-4) in mouse and human pancreas.
- Author(s)
  Moin Abu Saleh Md., 十枝内厚次，山口秀樹，迫田秀之，山崎基生，佐々木一樹，上野浩晶，平子智史，塩田清二，南野直人，中里雅光
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25293216
[Presentation] resistin like moleculeβを介したマクロファージ分化と炎症
- Author(s)
  櫛山暁史　菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] マクロファージresistin like molecule βによるインスリン抵抗性・動脈硬化発症の機序
- Author(s)
  櫛山暁史、菊池貴子、迫田秀之、藤城緑、山崎広貴、山本屋武、大久保博史、中津祐介、河津捷二、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] プロリン異性化酵素Pin1はAMPKγ subunitに結合し、活性を抑制する
- Author(s)
  中津祐介、岩下未咲、福嶋俊明、菊池貴子、櫛山暁史、迫田秀之、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] DPP4阻害薬anagliptinは、活性化マクロファージおよびマクロファージ共培養下脂肪細胞の炎症反応を抑制する
- Author(s)
  新城尊徳、岩下未咲、中津祐介、迫田秀之、藤城緑、櫛山暁史、鎌田英明、西村英紀、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[Presentation] キサンチンオキシダーゼ阻害剤FebuxostatによるNASH改善作用の検討
- Author(s)
  藤城緑、中津祐介、福嶋俊明、松永泰花、迫田秀之、櫛山暁史、山本屋武、西村英紀、浅野知一郎
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] Macrophage resistin-like molecule β is involved in atherosclerosis development.
- Author(s)
  Akifumi Kushiyama, Takako Kikuchi, Hideyuki Sakoda, Koichi Nishiyama, Hiroki Kurihara, Tomoichiro Asano, Shoji Kawazu
- Organizer
  The 18th International Vascular Biology Meeting
- Place of Presentation
  京都
- Year and Date
  2014-04-14 – 2014-04-17
- Data Source
  KAKENHI-PROJECT-25461372
[Presentation] プロリン異性化酵素Pin1はAMPKγ subunitに結合し、活性を抑制する
- Author(s)
  中津祐介、岩下未咲、福嶋俊明、菊池貴子、櫛山暁史、迫田秀之、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26293219
[Presentation] Pin1阻害薬Jugloneを用いたNASH治療効果の検討
- Author(s)
  山崎広貴、中津祐介、鎌田英明、西村英紀、菊池貴子、藤城緑、迫田秀之、浅野知一郎
- Organizer
  第５７回日本糖尿病学会
- Place of Presentation
  大阪
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26670451
[]

1. ASANO Tomoichiro (70242063)

# of Collaborated Projects: 9 results

# of Collaborated Products: 122 results
2. NAKATSU Yusuke (20452584)

# of Collaborated Projects: 5 results

# of Collaborated Products: 64 results
3. FUJISHIRO Midori (50420211)

# of Collaborated Projects: 4 results

# of Collaborated Products: 51 results
4. Nakazato Masamitsu (10180267)

# of Collaborated Projects: 4 results

# of Collaborated Products: 17 results
5. KUSHIYAMA Akifumi (30435820)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
6. 張維東 (90753616)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
7. UCHIJIMA Yasunobu (90272426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KURIHARA Hiroki (20221947)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. Yamaguchi Hideki (10305097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
10. Ueno Hiroaki (00381062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
11. Tsubouchi Hironobu (60573988)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. Shimizu Kouichirou (90711292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
13. FUKUSHIMA TOSHIAKI (70543552)

# of Collaborated Projects: 2 results

# of Collaborated Products: 21 results
14. HONDA HIROAKI (40245064)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
15. イスラムエムデイーヌルル (10870149)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
16. KAMATA Hideaki (10233925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
17. Toshinai Koji (80381101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
18. Tsuchimochi Wakaba (90573303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 柳重久 (60404422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 中里祐毅 (90885972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 小野啓 (10570616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
22. 神名麻智 (10619365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
23. 山本屋武 (50760013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
24. 庄嶋伸浩

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. Waise T. M. Zaved

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. Naznin Farhana

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. MOCHIZUKI Hitoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 金春奐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 西村英紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
30. 田中廣壽

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 松原昭郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 栗原由紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 片桐秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 石原寿光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 寒川賢治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 徳永文稔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakoda Hideyuki 迫田 秀之

SAKODA Hideyuki 迫田 秀之

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Regulatory mechanism of hepatic glucose metabolism by ghrelin and LEAP2Principal Investigator

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The mechanism of high fat diet induced neural inflammation and obesePrincipal Investigator

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Role of a novel LST8-binding protein on mTOR signal and glucose and lipid metabolismPrincipal Investigator

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The role of TORC signal on impaired glucose tolerance and cloning the new protein binding with TORC.Principal Investigator

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Sakoda Hideyuki 迫田秀之

SAKODA Hideyuki 迫田秀之