Niwa Junichi 丹羽淳一

… Alternative Names

Niwa Jun-ichi 丹羽淳一

NIWA Jun-ichi 丹羽淳一

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Researcher Number	50378022
External Links
Affiliation (Current)	2025: 愛知医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 愛知医科大学, 医学部, 教授 2018: 愛知医科大学, 医学部, 准教授 2007 – 2008: Aichi Medical University, 医学部, 講師 2007: 愛知医科大学, 医学部, 特任講師 2006: Nagoya University, Graduate School of Medicine, COE Research, 大学院医学系研究科, COE研究員 2005: 名古屋大学, 大学院・医学系研究科, COE研究員
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology Except Principal Investigator Neurology
Keywords	Principal Investigator 運動ニューロン / Dorfin / 疾患特異的iPS細胞 / iPS細胞 / 疾患iPS細胞 / 筋萎縮性側索硬化症 / ジスルフィド結合 / 変異SOD1 / 神経変性 / シナプス … More / 神経筋接合部（NMJ） / オプトジェネティクス / 骨格筋 / 神経筋接合部 / 運動ニューロン疾患 / 創薬スクリーニング / スクリーニング / 球脊髄性筋萎縮症 / ポリグルタミン病 / disulfide bond / neurodegeneration / motor neuron / mutant SOD1 / Amyotrophic lateral sclerosis / オリゴマー / プロテアソーム / ユビキチンリガーゼ / 翻訳後修飾 / TDP-43 / 核タンパク質 / プロテオーム / ユビキチン化 / タンパク質凝集 / 筋萎縮性側索硬化症(ALS) … More Except Principal Investigator プロテアソーム / 治療 / 分解 / 神経変性疾患 / 古細菌 / CAGリピート / ポリグルタミン / リュープロレリン / アンドロゲン受容体 / 球脊髄性筋萎縮症 / キメラタンパク質 / ユビキチンリガーゼ / 変異SOD1 / CHIP / Dorfin / 筋萎縮性側索硬化症 Less

The analysis of synapse pathology in motor neuron diseases using iPSCsPrincipal Investigator
- Principal Investigator
  
  丹羽淳一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Aichi Medical University
The establishment of drug screening system for polyglutamine disease using disease specific iPSCsPrincipal Investigator
- Principal Investigator
  
  Niwa Jun-ichi
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Aichi Medical University
Research on the molecular pathogenetic mechanism of tissue-specific toxicity mediated by ALS-linked mutant SOD1Principal Investigator
- Principal Investigator
  
  NIWA Jun-ichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Aichi Medical University
古細菌プロテアソームによる神経変性疾患の治療
- Principal Investigator
  
  祖父江元
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Dorfin-CHIP融合タンパク質による筋萎縮性側索硬化症(ALS)の治療
- Principal Investigator
  
  SOBUE Gen
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
An study on the mechanism of selective toxicity to motor neurons by mutant SOD1Principal Investigator
- Principal Investigator
  
  NIWA Jun-ichi
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University

All 2023 2021 2019 2018 2009 2008 2007 2006 2005

All Journal Article Presentation Book Patent

[Book] 看護のための最新医学講座第1巻脳・神経系疾患第2版.2005
- Author(s)
  丹羽淳一, 祖父江元
- Total Pages
  696
- Publisher
  中山書店
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients2023
- Author(s)
  Nakamura R, Tohnai G, Nakatochi M,… Onodera K, Ito T, Okada Y, Okano H, Sobue G
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 94 Issue: 10 Pages: 816-824
- DOI
  10.1136/jnnp-2022-330851
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15739, KAKENHI-PROJECT-19K06523, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-21K07471, KAKENHI-PROJECT-22K07359, KAKENHI-PROJECT-22K07509, KAKENHI-PROJECT-23K06955, KAKENHI-PROJECT-23K06975, KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-23K24249
[Journal Article] Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling2023
- Author(s)
  Rashid Muhammad Irfanur、Ito Takuji、Miya Fuyuki、Shimojo Daisuke、Arimoto Kanae、Onodera Kazunari、Okada Rina、Nagashima Takunori、Yamamoto Kazuki、Khatun Zohora、Shimul Rayhanul Islam、Niwa Jun-ichi、Katsuno Masahisa、Sobue Gen、Okano Hideyuki、Sakurai Hidetoshi、Shimizu Kazunori、Doyu Manabu、Okada Yohei
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 8146-8146
- DOI
  10.1038/s41598-023-34445-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15739, KAKENHI-PROJECT-22KJ2982, KAKENHI-PROJECT-21K07471, KAKENHI-PROJECT-23K06955, KAKENHI-PROJECT-23K06975, KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-20K16611, KAKENHI-PROJECT-23H00420, KAKENHI-PROJECT-23K24249
[Journal Article] Antiparkinsonian drugs as potent contributors to nocturnal sleep in patients with Parkinson's disease.2021
- Author(s)
  Taguchi S, Koide H, Oiwa H, Hayashi M, Ogawa K, Ito C, Nakashima K, Yuasa T, Yasumoto A, Ando H, Fujikake A, Fukuoka T, Tokui K, Izumi M, Tsunoda Y, Kawagashira Y, Okada Y, Niwa JI, Doyu M.
- Journal Title
  
  PLoS One.
  
  Volume: 16 Issue: 7 Pages: e0255274-e0255274
- DOI
  10.1371/journal.pone.0255274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07539, KAKENHI-PROJECT-19K07969, KAKENHI-PROJECT-21K07471, KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-19K17247, KAKENHI-PROJECT-19H03576
[Journal Article] Motor Improvement-Related Regional Cerebral Blood Flow Changes in Parkinson’s Disease in Response to Antiparkinsonian Drugs2019
- Author(s)
  Taguchi Soutarou、Tanabe Nachi、Niwa Jun-ichi、Doyu Manabu
- Journal Title
  
  Parkinson's Disease
  
  Volume: 2019 Pages: 1-8
- DOI
  10.1155/2019/7503230
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07539
[Journal Article] Maximum Walking Speed at Discharge Could Be a Prognostic Factor for Vascular Events in Patients With Mild Stroke: A Cohort Study2019
- Author(s)
  Kawajiri Hiroyuki、Mishina Hiromi、Asano Sho、Kono Yuji、Hayashi Hironori、Niwa Jun-ichi、Doyu Manabu、Kimura Shinya、Yamada Sumio
- Journal Title
  
  Archives of Physical Medicine and Rehabilitation
  
  Volume: 100 Issue: 2 Pages: 230-238
- DOI
  10.1016/j.apmr.2018.05.025
- NAID
  120006643291
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07539
[Journal Article] ES細胞由来運動神経細胞移植による末梢神経の運動機能再建2018
- Author(s)
  新海宏明、丹羽智史、佐伯将臣、平田仁、岡田洋平
- Journal Title
  
  整形外科
  
  Volume: 69 Pages: 1322-1322
- Data Source
  KAKENHI-PROJECT-18K07539
[Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009
- Author(s)
  Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G.
- Journal Title
  
  J Biol Chem (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2009
- Author(s)
  Sone J, Niwa J, Kawai K, Ishigaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  J Neurosci Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Dorfin ameliorates phenotypes in a transgenic mouse model of amyotrophic lateral sclerosis2009
- Author(s)
  Sone J, Niwa J, Kawai K, Is higaki S, Yamada S, Adachi H, Katsuno M, Tanaka F, Doyu M, Sobue G
- Journal Title
  
  J Neurosci Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009
- Author(s)
  Iguchi Y, Katsuno M, Niwa J, Yamada S, Sone J, Waza M, Adachi H, Tanaka F, Nagata K, Arimura N, Watanabe T, Kaibuchi K, Sobue G
- Journal Title
  
  J Biol Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.2007
- Author(s)
  Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G.
- Journal Title
  
  Neurobiol Dis. 25
  
  Pages: 331-41
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Gene expression profiling toward understanding of ALS pathogenesis.2007
- Author(s)
  Tanaka F, Niwa J, Ishigaki S, Katsuno M, Waza M, Yamamoto M, Doyu M, Sobue G.
- Journal Title
  
  Ann N Y Acad Sci. 1086
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of famlial amyotrophic lateral sclerosis-linked mutant SOD1.2007
- Author(s)
  Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  J Biol Chem. 282
  
  Pages: 28087-28095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.2007
- Author(s)
  Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G
- Journal Title
  
  Neurobiol Dis. 25
  
  Pages: 331-341
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity.2007
- Author(s)
  Ishigaki S, Niwa J, Yamada S, Takaiashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G.
- Journal Title
  
  Neurobiol Dis. 25
  
  Pages: 331-341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-1inked mutant SOD1.2007
- Author(s)
  Niwa J, Yamada S, Ishigaki S, et. al.
- Journal Title
  
  The Journal of biological chemistry Sep21;282(383)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659224
[Journal Article] Dorfin-CHIP chimeric proteins potently ubiquitylate and degrade familial ALS-related mutant SOD1 proteins and reduce their cellular toxicity2007
- Author(s)
  Ishigaki S, Niwa J, Yamada S, Takahashi M, Ito T, Sone J, Doyu M, Urano F, Sobue G.
- Journal Title
  
  Neurobiol Dis 25
  
  Pages: 331-341
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Gene expressions specifically detected in motor neurons(dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C)differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis.2007
- Author(s)
  Jiang YM, Yamamoto M, Tanaka F, shigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizune Y, Sobue G.
- Journal Title
  
  J Neuropathol Exp Neural. 66
  
  Pages: 617-627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Gene expression profiling toward understanding of ALS pathogenesis2007
- Author(s)
  Tanaka F, Niwa J, Ishigaki S, Katsuno M, Waza M, Yamamoto M, Doyu M, Sobue G.
- Journal Title
  
  Ann N Y Acad Sci 1086
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Gene expressions specifically detected in motor neurons (dynactin 1, early growth response 3, acetyl-CoA transporter, death receptor 5, and cyclin C) differentially correlate to pathologic markers in sporadic amyotrophic lateral sclerosis2007
- Author(s)
  Jiang YM, Yamamoto M, Tanaka F, Ishigaki S, Katsuno M, Adachi H, Niwa J, Doyu M, Yoshida M, Hashizume Y, Sobue G.
- Journal Title
  
  J Neuropathol Exp Neurol 66
  
  Pages: 617-627
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] Disulfide bond mediates aggregation, toxicity, and ubiquitylation of familial amyotrophic lateral sclerosis-linked mutant SOD12007
- Author(s)
  Niwa J, Yamada S, Ishigaki S, Sone J, Takahashi M, Katsuno M, Tanaka F, Doyu M, Sobue G.
- Journal Title
  
  J Biol Chem 282
  
  Pages: 28087-28095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590987
[Journal Article] 運動ニューロン病とユビキチン.2006
- Author(s)
  丹羽淳一, 祖父江元
- Journal Title
  
  蛋白質核酸酵素 51
  
  Pages: 1423-1427
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Gene expression profiling toward understanding of ALS pathogenesis.2006
- Author(s)
  Tanaka F, Niwa J, Ishigaki S, Katsuno M, Waza M, Yamamoto M, Doyu M, Sobue G.
- Journal Title
  
  Ann N Y Acad Sci. 1086
  
  Pages: 1-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.2006
- Author(s)
  Yamada S, Niwa J, Ishigaki S, Takahashi M, Ito T, Sone J, Doyu M, Sobue G.
- Journal Title
  
  J Biol Chem.
  
  Pages: 28123842-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Motor neuron disease and ubiquitin-proteasome system dysfunction2006
- Author(s)
  Niwa J, Sobue G.
- Journal Title
  
  Tanpakushitsu Kakusan Koso. 51
  
  Pages: 1423-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Gene expression profiling toward understanding of ALS pathogenesis.2006
- Author(s)
  Tanaka F, Niwa J, Ishigaki S, Katsuno M, Waza M, Yamamoto M, Doyu M, Sobue G
- Journal Title
  
  Ann N Y Acad Sci. 1086
  
  Pages: 1-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin.2006
- Author(s)
  Huang Y, Niwa J, Sobue G, Breitwieser GE
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 11610-11617
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin.2006
- Author(s)
  Huang Y, Niwa J, Sobue G, Breitwieser GE.
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 11610-7
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells.2006
- Author(s)
  Yamada S, Niwa J, Ishigaki S, Takahashi M, Ito T, Sone J, Doyu M, Sobue G
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 23842-23851
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Calcium sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin.2006
- Author(s)
  Huang Y, Niwa J, Sobue G, Breitwieser GE
- Journal Title
  
  J Biol Chem. (in press)
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Tuft-shaped astrocytes in Lewy body disease. Acta Neuropathol (Berl).2005
- Author(s)
  Hishikawa N, Hashizume Y, Yoshida M, Niwa J, Tanaka F, Sobue G
- Journal Title
  
  Acta Neuropathol (Berl). 109
  
  Pages: 373-380
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Tuft-shaped astrocytes in Lewy body disease.2005
- Author(s)
  Hishikawa N, Hashizume Y, Yoshida M, Niwa J, Tanaka F, Sobue G.
- Journal Title
  
  Acta Neuropathol (Berl). 109
  
  Pages: 373-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Gene expression profile of motor neurons in sporadic amyotrophic lateral sclerosis.2005
- Author(s)
  Jiang YM, Yamamoto M, Kobayashi Y, Yoshihara T, Liang Y, Terao S, Takeuchi H, Ishigaki S, Katsuno M, Adachi H, Niwa J, Tanaka F, Doyu M, Yoshida M, Hashizume Y, Sobue G
- Journal Title
  
  Ann Neurol 57
  
  Pages: 236-251
- Data Source
  KAKENHI-PROJECT-17659261
[Journal Article] Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis.2005
- Author(s)
  Jiang YM, Yamamoto M, Kobayashi Y, Yoshihara T, Liang Y, Terao S, Takeuchi H, Ishigaki S, Katsuno M, Adachi H, Niwa J, Tanaka F, Doyu M, Yoshida M, Hashizume Y, Sobue G.
- Journal Title
  
  Ann Neurol. 57
  
  Pages: 236-51
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Journal Article] Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis.2005
- Author(s)
  Jiang YM, Yamamoto M, Kobayashi Y, Yoshihara T, Liang Y, Terao S, Takeuchi H, Ishigaki S, Katsuno M, Adachi H, Niwa J
- Journal Title
  
  Ann Neurol. 57
  
  Pages: 236-251
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Patent] 凝集体形成性タンパク質分解用の発現コントラクト、及び凝集体形成性タンパク質が凝集体を形成することを抑制する方法2006
- Inventor(s)
  山田新一, 丹羽淳一, 祖父江元
- Industrial Property Rights Holder
  山田新一, 丹羽淳一, 祖父江元
- Filing Date
  2006-03-20
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590870
[Presentation] Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients2023
- Author(s)
  Nakamura R, Tohnai G, Nakatochi M, Niwa JI, Doyu M, Fujimori K, Morimoto S, Okada Y, Okano H, Sobue G et al.,
- Organizer
  34th international symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07539
[Presentation] 筋萎縮性側索硬化症（ALS）新規治療基軸エダラボンの臨床効果に関する検証2023
- Author(s)
  湯淺知子，川頭祐一，丹羽淳一，道勇学
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07471
[Presentation] 筋萎縮性側索硬化症（ALS）新規治療基軸エダラボンの臨床効果に関する検証2023
- Author(s)
  湯淺知子，川頭祐一，丹羽淳一，道勇学
- Organizer
  第64回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K07539
[Presentation] ALSの早期診断・遺伝子診断2023
- Author(s)
  中村亮一、熱田直樹，藤内玄規，丹羽淳一，道勇学，祖父江元
- Organizer
  第64回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K07539
[Presentation] ALSの早期診断・遺伝子診断2023
- Author(s)
  中村亮一、熱田直樹，藤内玄規，丹羽淳一，道勇学，祖父江元
- Organizer
  第64回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K07471
[Presentation] Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients2023
- Author(s)
  Nakamura R, Tohnai G, Nakatochi M, Niwa JI, Doyu M, Fujimori K, Morimoto S, Okada Y, Okano H, Sobue G et al.,
- Organizer
  34th international symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07471
[Presentation] 脳卒中患者における自律神経機能と病状との関連2021
- Author(s)
  中島康自, 小出弘文, 林未久, 伊藤千弘, 湯淺知子, 安本明弘, 安藤宏明, 田口宗太郎, 藤掛彰史, 福岡敬晃, 徳井啓介, 川頭祐一, 岡田洋平, 丹羽淳一, 道勇学
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-21K07471
[Presentation] 脳卒中患者における自律神経機能と病状との関連2021
- Author(s)
  中島康自, 小出弘文, 林未久, 伊藤千弘, 湯淺知子, 安本明弘, 安藤宏明, 田口宗太郎, 藤掛彰史, 福岡敬晃, 徳井啓介, 川頭祐一, 岡田洋平, 丹羽淳一, 道勇学
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-18K07539
[Presentation] 末梢神経損傷におけるヒトiPS細胞由来運動神経前駆細胞を用いた運動機能再建2019
- Author(s)
  丹羽智史、佐伯将臣、新海宏明、栗本秀、平田仁、岡田洋平
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K07539
[Presentation] 孤発性ALS病態関連分子の探索と疾患モデルの開発2008
- Author(s)
  田中章景, 和座雅浩, 丹羽淳一, 山本正彦, 祖父江元
- Organizer
  第49回日本神経学会総会
- Place of Presentation
  横浜
- Year and Date
  2008-05-17
- Data Source
  KAKENHI-PROJECT-19590987
[Presentation] 変異SOD1と特異的に結合するタンパク質の探索同定2007
- Author(s)
  丹羽淳一、山田新一、曽根淳、高橋美穂、道勇学、祖父江元
- Organizer
  第48回日本神経学会総会
- Place of Presentation
  名古屋
- Year and Date
  2007-05-17
- Data Source
  KAKENHI-PROJECT-19590987

1. SOBUE Gen (20148315)

# of Collaborated Projects: 5 results

# of Collaborated Products: 30 results
2. TANAKA Fumiaki (30378012)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. 岡田洋平 (30383714)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
4. 伊藤卓治 (30794151)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 山本正彦 (40378039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 山田新一 (10467285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小野寺一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Niwa Junichi 丹羽 淳一

Niwa Jun-ichi 丹羽 淳一

NIWA Jun-ichi 丹羽 淳一

Research Projects

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The analysis of synapse pathology in motor neuron diseases using iPSCsPrincipal Investigator

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The establishment of drug screening system for polyglutamine disease using disease specific iPSCsPrincipal Investigator

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Research on the molecular pathogenetic mechanism of tissue-specific toxicity mediated by ALS-linked mutant SOD1Principal Investigator

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古細菌プロテアソームによる神経変性疾患の治療

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Dorfin-CHIP融合タンパク質による筋萎縮性側索硬化症(ALS)の治療

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An study on the mechanism of selective toxicity to motor neurons by mutant SOD1Principal Investigator

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[Book] 看護のための最新医学講座 第1巻 脳・神経系疾患 第2版.2005

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[Journal Article] Genetic factors affecting survival in Japanese patients with sporadic amyotrophic lateral sclerosis: a genome-wide association study and verification in iPSC-derived motor neurons from patients2023

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[Journal Article] Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling2023

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[Journal Article] Antiparkinsonian drugs as potent contributors to nocturnal sleep in patients with Parkinson's disease.2021

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[Journal Article] Motor Improvement-Related Regional Cerebral Blood Flow Changes in Parkinson’s Disease in Response to Antiparkinsonian Drugs2019

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[Journal Article] Maximum Walking Speed at Discharge Could Be a Prognostic Factor for Vascular Events in Patients With Mild Stroke: A Cohort Study2019

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[Journal Article] ES細胞由来運動神経細胞移植による末梢神経の運動機能再建2018

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[Journal Article] TDP-43 depletion induces neuronal cell damage through dysregulation of Rho family GTPases2009

Author(s)

Niwa Junichi 丹羽淳一

Niwa Jun-ichi 丹羽淳一

NIWA Jun-ichi 丹羽淳一

[Book] 看護のための最新医学講座第1巻脳・神経系疾患第2版.2005