NOGUCHI HIROFUMI 野口洋文

… Alternative Names

NOGUCHI Hirofumi 野口洋文

野口洋文ノグチヒロフミ

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Researcher Number	50378733
Other IDs	https://orcid.org/0000-0002-0880-6805
Affiliation (Current)	2025: 琉球大学, 医学(系)研究科(研究院), 教授
Affiliation (based on the past Project Information) *help	2014 – 2024: 琉球大学, 医学(系)研究科(研究院), 教授 2017: 琉球大学, 医学系研究科, 教授 2015: 岡山大学医学部, 再生医学, 客員研究員 2014 – 2015: 琉球大学, 医学部, 教授 2014: 琉球大学, 医学(系)研究科(大学院), 教授 … More 2014: 琉球大学, 医学部再生医学講座, 教授 2013 – 2014: 独立行政法人国立病院機構(千葉東病院臨床研究センター), その他部局等, その他 2013: 独立行政法人国立病院機構(千葉東病院臨床研究センター), 外科, 非常勤医師 2013: 独立行政法人国立病院機構(千葉東病院臨床研究センター), 外科・移植再生学, 研究員 2013: 独立行政法人国立病院機構(千葉東病院臨床研究センター), 移植・再生医療研究部, 研究員 2013: 独立行政法人国立病院機構, 千葉東病院研究センター, 研究員 2013: 独立行政法人国立病院機構, 千葉東病院臨床研究センター, 研究員 2011 – 2013: 岡山大学, 医学部, 客員研究員 2012: 岡山大学, 医学部, その他 2012: 岡山大学, 医学部, 研究員 2005: 京大, 医学(系)研究科(研究院) Less
Review Section/Research Field	Principal Investigator General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Digestive surgery Except Principal Investigator Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related / General surgery / Basic Section 55010:General surgery and pediatric surgery-related / Urology / Basic Section 57040:Regenerative dentistry and dental engineering-related … More / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Medical systems / Tumor biology / Life / Health / Medical informatics / Medical engineering assessment / Pediatric surgery / Tumor biology / Orthodontic/Pediatric dentistry / Dental engineering/Regenerative dentistry Less
Keywords	Principal Investigator iTS細胞 / 膵幹細胞 / 転写因子 / ヒトiTS細胞 / 膵島 / ヒトiTP細胞 / 膵島移植 / 免疫抑制剤 / 奇形腫 / 山中因子 … More / 低分子化合物 / YAP / iTP細胞 / 脾内移植 / ブタ / in vivo bioreactor / インスリン分泌細胞 / 膵組織 / iTS-P細胞 / 再生医学 / 体性幹細胞 / iPS細胞 / 再生医療 / カルシニューリンインヒビター / 蛋白導入法 / RCAN蛋白 / 細胞毒性 / 糖尿病 / 副作用 / 臓器保存液 / 連続比重・密度勾配による純化 / 新規臓器保存液（HN-1溶液） / JNK抑制ペプチド / 連続密度勾配 / 連続比重勾配 / 膵島純化 / 新規臓器保存液 / JNK抑制剤 / 膵島分離 / RCAN / NFAT / カルシニューリン … More Except Principal Investigator iPS細胞 / 幹細胞 / ヒト乳歯歯髄細胞 / 再生医療 / 再生医学 / 乳歯 / 再生歯学 / アルカリホスファターゼ / 遺伝子工学的手法 / 糖尿病 / iTS細胞 / 組織特異的幹細胞 / 再生 / 歯髄幹細胞 / 移植・再生医療 / 膵島移植 / ゲノム編集 / ALP / HPP / 1型糖尿病 / インスリン分泌細胞 / 膵幹細胞 / 歯髄細胞 / 乳歯歯髄幹細胞 / 膵β細胞 / 細胞骨格 / 間葉系幹細胞 / 細胞・組織 / 人工間葉系幹細胞 / 脂肪由来幹細胞 / 人工間葉系幹細胞(iTS-M) / 移植医療 / マイクロデバイス / 腎臓 / PiggyBacシステム / 男性ホルモン / odontoblast / ameloblast / 膵臓保存 / 持続冷却潅流保存 / 臓器保存 / モデルマウス / 低ホスファターゼ症 / 小児 / 細胞移植治療 / 抗線維化 / 肺線維症 / iTS-M / 多能性幹細胞 / 細胞工学的手法 / 尿路性器癌 / microtubule / in vivo投与モデル / Dynamin / 癌 / in vivo投与法 / エンドサイトーシス / in vivo投与 / 細胞内輸送 / 癌創薬 / 三次元培養 / ＴＡＳＣＬ / インスリン分泌細胞分化誘導法 / 組織特異的膵幹細胞 / 血糖降下作用 / 糖尿病マウス / 3次元培養 / TASCL / iTS-P / 不死化 / インスリン分泌β細胞 / １型糖尿病 / インスリン分泌β細胞への分化 / 膵臓 / ナイーブ幹細胞 / 体性幹細胞 / 細胞培養 / 移植外科学 / 小児外科学 / 外科学一般 / 外科系臨床医学 / システム / 機能評価 / 凍結保護剤 / 凍結保存 / 組織構築物 / マイクロ・ナノデバイス / 前立腺 / 腫瘍学 / がん制御遺伝子 / 代謝 / 悪性形質 / SGTA / REIC/Dkk-3 / 内分泌療法抵抗性 / 前立腺癌 / DNAコンピュータ / 分子ロボティクス / 歯学 / HDDPC / Epiblast Stem Cells / Humann / SSEA-1 / Naive Stem Cell / 細胞移植法 / 組織除去 / 局所注入 / 細胞移植 / piggybacシステム / CRISPR/Cas9 / 生体内遺伝子導入 / 抗アポプトーシスペプチド / 膵島細胞 / p38MARK / ペプチド / 蛋白導入システム / アポトーシス / p38MAPK / エピジェネティックメモリ / ES / iPS / 組織特異的幹細胞(iTS) / VEE-RNAベクター / VEE-RNA vector / ADSCs / reprogramming factors / iPS cells / iTS-M cells / 医療技術 / 毒性評価 / 細胞医療 / 磁性ナノ粒子 / クラスター / 細胞 / RedCasDSPPni / pCXLE-pac / CRISPR/Cas9システム / DSPP遺伝子 / CRIPR/Cas9システム / feeder細胞 / 乳歯歯髄細胞 / 神経幹細胞 / 持続冷却灌流保存 / アルカリ性フォスファターゼ / アルカリフォスファターゼ / 選択的濃縮 / 小腸不全」 / 小腸幹細胞 / 小腸不全 / Organoid units / ラット / 小腸粘膜幹細胞 / 小腸化大腸 / アンドロゲン / 乳歯歯髄 / 小児歯科学 / 遺伝子工学的処理 / Oct-3/4 / 癌幹細胞 / iPS 細胞 / 遺伝子工学 / odontblast / Tgマウス / 歯形成 / 灌流保存 / 膵ランゲルハンス島（膵島） / 移植 Less

ヒト乳歯歯髄幹細胞の分化多能性におけるアルカリホスファターゼの機能解明
- Principal Investigator
  
  稲田絵美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
Induction of human pancreatic stem cells by novel transcription factors without Yamanaka factorsPrincipal Investigator
- Principal Investigator
  
  野口洋文
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  University of the Ryukyus
ヒト乳歯歯髄細胞への分子生物学的介入による幹細胞誘導とそれを用いた機能解析
- Principal Investigator
  
  窪田直子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
新規生体内ゲノム編集法による低ホスファターゼ症モデルマウス作製とその応用
- Principal Investigator
  
  齊藤陽子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Asahi University
人工間葉系幹細胞を用いた肺線維症モデルマウスに対する効果
- Principal Investigator
  
  潮平知佳
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  University of the Ryukyus
Induction of insulin secreting cell via human iPS cells derived from deciduous teeth using a novel organ culture method
- Principal Investigator
  
  齊藤一誠
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Asahi University
Enrichment and functional analysis of human deciduous dental pulp stem cells for tooth regeneration
- Principal Investigator
  
  Inada Emi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
Induction of tissue-specific stem cells by novel transcription factors and/or small-molecule compoundsPrincipal Investigator
- Principal Investigator
  
  Noguchi Hirofumi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  University of the Ryukyus
Molecular biological approaches to gene therapy for hypophosphatosis
- Principal Investigator
  
  Saito-Iwase Yoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Asahi University
  Niigata University
Functional analysis of alkaline phosphatase, a stem cell marker, using human deciduous dental pulp cells derived from the patient with Hypophosphatasia (HPP)
- Principal Investigator
  
  Kubota Naoko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
Differentiatio of human stem cells into pancreatic islets using porcine body as in vivo bioreactorPrincipal Investigator
- Principal Investigator
  
  Noguchi Hirofumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  University of the Ryukyus
Development of the differentiation derivative methods from induced tissue-specific pancreatic stem cells using TASCL to insulin excretory cells
- Principal Investigator
  
  SHIOHIRA CHIKA
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  University of the Ryukyus
Elucidation of molecular transport control systems based on cytoskeleton dynamics and new developments in innovative cancer drug discovery.
- Principal Investigator
  
  Watanabe Masami
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Okayama University
Development of culture method to promote differentiation induction of pancreatic beta cells
- Principal Investigator
  
  中島義基
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  University of the Ryukyus
Isolation and characterization of somatic stem cells from human deciduous tooth-derived dental pulp cells by genetic engineering techniques
- Principal Investigator
  
  Inada Emi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kagoshima University
初期胚特異抗原SSEA-1が高未分化iPS細胞を特定するマーカーであることの証明
- Principal Investigator
  
  澤味規
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Niigata University
A study on molecular robotics blood glucose level control method with NOD mice
- Principal Investigator
  
  KONAGAYA Akihiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Life / Health / Medical informatics
- Research Institution
  Tokyo Institute of Technology
Regeneration of insulin producing cells from Human deciduous dental pulp cell derived iPS cells
- Principal Investigator
  
  Saitoh Issei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Niigata University
Induction of human iTS-P and iTS-L cells using iPS cell technologyPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hirofumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  University of the Ryukyus
Induction of Expandable Adipose-Derived Mesenchymal Stem Cells from Aged Mesenchymal Stem Cells by a Synthetic Self-Replicationg RNA.
- Principal Investigator
  
  Shiohira Chika
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  University of the Ryukyus
Development and usage of p38MAPK inhibitory peptides
- Principal Investigator
  
  Kurima Kiyoto
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  University of the Ryukyus
Development of gene transfer to peripheral tissues surrounding tooth (GTPT) for the tissue around the root forming apex of juvenile mice and its application
- Principal Investigator
  
  Kubota Naoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kagoshima University
Regeneration strategy of the functional renal corpuscle using renal stem cells
- Principal Investigator
  
  Watanabe Masami
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University
次世代型標的遺伝子破壊法CRISPR/Cas9システムの歯学領域への応用
- Principal Investigator
  
  鹿児島暁子
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Niigata University
Elucidation of the unitary regulation on the malignant transformation and androgen insensitivity in prostate cancer.
- Principal Investigator
  
  Watanabe Masami
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Tumor biology
- Research Institution
  Okayama University
Development of cryopreservation system for cells and tissue constructs in regenerative medicine and transplantation
- Principal Investigator
  
  MIYAMOTO Yoshitaka
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  National Center for Child Health and Development
Continuous hypothermic machine perfusion preservation of pancreas for efficient islet transplantation
- Principal Investigator
  
  Akutsu Naotake
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  National Hospital Organization Chiba-East-Hospital
The isolation of stem cells from the human exfoliated deciduous teeth by genetic engineering
- Principal Investigator
  
  SAWAMI Tadashi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Niigata University
A novel NFAT inhibitory peptide (RCAN-11R) provides immunosuppression.Principal Investigator
- Principal Investigator
  
  NOGUCHI Hirofumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  University of the Ryukyus
Development of xeno-free human feeder cell with multi-function derived from the dental pulp cell
- Principal Investigator
  
  Issei Saitoh
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Niigata University
The tooth-format cellular differentiating regulation from iPSCs
- Principal Investigator
  
  Issei Saitoh
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Niigata University
Establishment and applicational research of androgen producing stem cells
- Principal Investigator
  
  Sugimoto Morito
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  Okayama University
The study of regeneration of fetal small intestinal mucosa on the denuded colon
- Principal Investigator
  
  NODA Takuo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatric surgery
- Research Institution
  Okayama University
Preferential enrichment and characterization of human dental pulp stem cell via a genetic engineering-based approach
- Principal Investigator
  
  Inada Emi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kagoshima University
Induction and isolation of renal stem cells and establishment of foundation for renal regeneration research.
- Principal Investigator
  
  Watanabe Masami
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Urology
- Research Institution
  Okayama University
Construction of a cytotoxicity and function evaluation system using combinatorial cell clusters with magnetic nanoparticles
- Principal Investigator
  
  MIYAMOTO Yoshitaka
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical engineering assessment
- Research Institution
  National Center for Child Health and Development
Establishment of 4th generation of islet isolation and the clinical applicationPrincipal Investigator
- Principal Investigator
  
  NOGUCHI Hirofumi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  University of the Ryukyus
  Clinical research Center, Chiba-East National Hospital, National Hospital Organization
  Okayama University
Oct-3/4, a member of the family of POU-domain transcriptional factors can be the promising markers for cancer stem cells.
- Principal Investigator
  
  KUBOTA Naoko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor biology
- Research Institution
  Kagoshima University
Effectiveness for islet isolation by hypothermic machine perfusion presevation of pancreas
- Principal Investigator
  
  AKUTSU Naotake
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Clinical research Center, Chiba-East National Hospital, National Hospital Organization
Production and application of a dental hypoplasia mouse model using a specific organization and a cell disruption system
- Principal Investigator
  
  MATSUMOTO Yuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dental engineering/Regenerative dentistry
- Research Institution
  Kagoshima University
Enrichment of the tooth constitution cell derived from human iPS cells using an original technique
- Principal Investigator
  
  HASEGAWA Hiroko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Kagoshima University
蛋白導入法を用いた新規免疫抑制剤の開発Principal Investigator
- Principal Investigator
  
  野口洋文
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General surgery
- Research Institution
  Okayama University
新規細胞導入ペプチドによる膵島移植後の生着率向上効果の検討Principal Investigator
- Principal Investigator
  
  野口洋文
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
ヒト膵島分離後の膵非内分泌組織からの膵幹細胞の同定と膵β細胞への分化誘導法の確立Principal Investigator
- Principal Investigator
  
  野口洋文
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University

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All Journal Article Presentation Patent

[Journal Article] Establishment of Induced Pancreatic Stem Cells by Yes Associated Protein 12024
- Author(s)
  Noguchi, Hirofumi; Miyagi-Shiohira, Chika; Nakashima, Yoshiki; Onishi, Yuka; Saitoh, Issei; Watanabe, Masami
- Journal Title
  
  Cell Transplantation
  
  Volume: -
- DOI
  10.1177/09636897241248942
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08759
[Journal Article] Cytoprotective Effect of Pteryxin on Insulinoma MIN6 Cells Due to Antioxidant Enzymes Expression via Nrf2/ARE Activation2023
- Author(s)
  Taira Junsei、Tsuda Ryuji、Miyagi-Shiohira Chika、Noguchi Hirofumi、Ogi Takayuki
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 3 Pages: 693-693
- DOI
  10.3390/antiox12030693
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08759, KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-23K27664
[Journal Article] Clinical Islet Transplantation Covered by Health Insurance in Japan2022
- Author(s)
  Noguchi Hirofumi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 14 Pages: 3977-3977
- DOI
  10.3390/jcm11143977
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745
[Journal Article] Pancreas Preservation with a Neutrophil Elastase Inhibitor, Alvelestat, Contributes to Improvement of Porcine Islet Isolation and Transplantation.2022
- Author(s)
  Ryusei Otsuka, Chika Miyagi-Shiohira, Kazuho Kuwae, Kai Nishime, Yoshihito Tamaki, Tasuku Yonaha, Mayuko Sakai-Yonaha, Ikuo Yamasaki, Misaki Shinzato, Issei Saitoh, Masami Watanabe, Hirofumi Noguchi
- Journal Title
  
  Journal of clinical medicine
  
  Volume: 11.15 Issue: 15 Pages: 4290-4290
- DOI
  10.3390/jcm11154290
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08759, KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745
[Journal Article] Induced hepatic stem cells are suitable for human hepatocyte production2022
- Author(s)
  Nakashima Yoshiki、Miyagi-Shiohira Chika、Saitoh Issei、Watanabe Masami、Matsushita Masayuki、Tsukahara Masayoshi、Noguchi Hirofumi
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 10 Pages: 105052-105052
- DOI
  10.1016/j.isci.2022.105052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-22K08759
[Journal Article] Protocol for the generation of human induced hepatic stem cells using Sendai virus vectors2022
- Author(s)
  Noguchi Hirofumi、Nakashima Yoshiki、Watanabe Masami、Matsushita Masayuki、Tsukahara Masayoshi、Saitoh Issei、Miyagi-Shiohira Chika
- Journal Title
  
  STAR Protocols
  
  Volume: 3 Issue: 4 Pages: 101884-101884
- DOI
  10.1016/j.xpro.2022.101884
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745
[Journal Article] AP39, a Mitochondrial-Targeted H2S Donor, Improves Porcine Islet Survival in Culture.2022
- Author(s)
  Misaki Shinzato , Chika Miyagi-Shiohira , Kazuho Kuwae , Kai Nishime , Yoshihito Tamaki , Tasuku Yonaha , Mayuko Sakai-Yonaha , Ikuo Yamasaki , Ryusei Otsuka , Issei Saitoh , Masami Watanabe , Hirofumi Noguchi
- Journal Title
  
  Journal of clinical medicine
  
  Volume: 11.18 Issue: 18 Pages: 5385-5385
- DOI
  10.3390/jcm11185385
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08759, KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-23K24535
[Journal Article] Functional Evaluation of 3D Liver Models Labeled with Polysaccharide Functionalized Magnetic Nanoparticles2022
- Author(s)
  Miyamoto Yoshitaka、Koshidaka Yumie、Murase Katsutoshi、Kanno Shoichiro、Noguchi Hirofumi、Miyado Kenji、Ikeya Takeshi、Suzuki Satoshi、Yagi Tohru、Teramoto Naozumi、Hayashi Shuji
- Journal Title
  
  Materials
  
  Volume: 15 Issue: 21 Pages: 7823-7823
- DOI
  10.3390/ma15217823
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K18298, KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-19H01067, KAKENHI-PROJECT-19H03538, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-16KK0192
[Journal Article] The Role of Genetically Modified Human Feeder Cells in Maintaining the Integrity of Primary Cultured Human Deciduous Dental Pulp Cells.2022
- Author(s)
  Ibano N、Inada E、Otake S、Kiyokawa Y、Sakata K、Sato M、Kubota N、Noguchi H、Iwase Y、Murakami T、Sawami T、Kakihara Y、Maeda T、Terunuma M、Terao Y、Saitoh I
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 20 Pages: 6087-6087
- DOI
  10.3390/jcm11206087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10165, KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-20K10009, KAKENHI-PROJECT-20K10210, KAKENHI-PROJECT-23K24535
[Journal Article] RNA analysis based on a small number of manually isolated fixed cells (RNA-snMIFxC) to profile stem cells from human deciduous tooth-derived dental pulp cells2021
- Author(s)
  Emi Inada、Issei Saitoh、Naoko Kubota、Yoko Iwase、Yuki Kiyokawa、Hirofumi Noguchi、Youichi Yamasaki、Masahiro Sato
- Journal Title
  
  Biological Procedures Online.
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04412
[Journal Article] Pancreas Preservation in Modified Histidine-lactobionate Solution Is Superior to That in University of Wisconsin Solution for Porcine Islet Isolation2021
- Author(s)
  Sakai-Yonaha Mayuko、Miyagi-Shiohira Chika、Kuwae Kazuho、Tamaki Yoshihito、Nishime Kai、Yonaha Tasuku、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Transplantation
  
  Volume: Publish Ahead of Print Issue: 9 Pages: 1770-1776
- DOI
  10.1097/tp.0000000000003636
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04412, KAKENHI-PROJECT-22K08759, KAKENHI-PROJECT-21K19537, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-23K24535
[Journal Article] In vivo evaluation ofGG2-GG1/ A2 element activity in the insulin promoter region using the CRISPR-Cas9 system2021
- Author(s)
  Hirofumi Noguchi Chika Miyagi Shiohira Takao Kinjo Issei Saitoh MasamiWatanabe
- Journal Title
  
  Scientifc Reports
  
  Volume: 11:20290 Issue: 1 Pages: 20290-20290
- DOI
  10.1038/s41598-021-99808-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09051, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-20K08655, KAKENHI-PROJECT-21K19537
[Journal Article] Pancreas preservation with amphotericin B deteriorates islet yield for porcine islet isolation2021
- Author(s)
  Sayaka Sawada Chika Miyagi‐Shiohira Kazuho Kuwae Hirofumi Noguchi
- Journal Title
  
  pancreas
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09051
[Journal Article] RNA analysis based on a small number of manually isolated fixed cells (RNA-snMIFxC) to profile stem cells from human deciduous tooth-derived dental pulp cells2021
- Author(s)
  Inada E, Saitoh I, Kubota N, Iwase Y, Kiyokawa Y, Noguchi H, Yamasaki Y, Sato M
- Journal Title
  
  Biological Procedure Online
  
  Volume: 23 Issue: 1 Pages: 12-12
- DOI
  10.1186/s12575-021-00149-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06372, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-20K10210, KAKENHI-PROJECT-21K10165, KAKENHI-PROJECT-21K19537
[Journal Article] Pancreas Preservation in Modified Histidine-lactobionate Solution Is Superior to That in University of Wisconsin Solution for Porcine Islet Isolation2021
- Author(s)
  Mayuko Sakai-Yonaha Chika Miyagi-Shiohira Kazuho Kuwae Hirofumi Noguchi
- Journal Title
  
  pancreas
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09051
[Journal Article] Tissue-nonspecific alkaline phosphatase, a possible mediator of cell maturation: Towards a new paradigm2021
- Author(s)
  Sato M, Saitoh I, Kiyokawa, Iwase Y, Kubota N, Ibano N, Noguchi H, Yamasaki Y, Inada E
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 12 Pages: 3338-3338
- DOI
  10.3390/cells10123338
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06372, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-20K10009, KAKENHI-PROJECT-20K10210, KAKENHI-PROJECT-21K10165, KAKENHI-PROJECT-21K19537
[Journal Article] Induced Tissue-Specific Stem Cells (iTSCs): Their Generation and Possible Use in Regenerative Medicine2021
- Author(s)
  Saitoh Issei、Sato Masahiro、Kiyokawa Yuki、Inada Emi、Iwase Yoko、Ibano Natsumi、Noguchi Hirofumi
- Journal Title
  
  Pharmaceutics
  
  Volume: 13 Issue: 6 Pages: 780-780
- DOI
  10.3390/pharmaceutics13060780
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-20K10210, KAKENHI-PROJECT-21K10165, KAKENHI-PROJECT-21K19537
[Journal Article] RNA analysis based on a small number of manually isolated fixed cells (RNA-snMIFxC) to profile stem cells from human deciduous tooth-derived dental pulp cells2021
- Author(s)
  Inada E, Saitoh I, Kubota N, Iwase Y, Kiyokawa Y, Noguchi H, Yamasaki Y, Sato M
- Journal Title
  
  Biological Procedure Online
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09839
[Journal Article] Induced tissue-specific stem cells (iTSCs): their generation and possible use in regenerative medicine2021
- Author(s)
  Issei Saitoh, Masahiro Sato, Yuki Kiyokawa, Emi Inada, Yoko Iwase, Natsumi Ibano, Hirofumi Noguchi
- Journal Title
  
  Pharmaceutics
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04412
[Journal Article] Pancreas preservation with amphotericin B deteriorates islet yield for porcine islet isolation2021
- Author(s)
  Sawada Sayaka、Miyagi‐Shiohira Chika、Kuwae Kazuho、Tamaki Yoshihito、Nishime Kai、Sakai‐Yonaha Mayuko、Yonaha Tasuku、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Xenotransplantation
  
  Volume: 28 Issue: 4
- DOI
  10.1111/xen.12690
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-21K19537
[Journal Article] Gene Expression in Pancreatic Cancer-Like Cells and Induced Pancreatic Stem Cells Generated by Transient Overexpression of Reprogramming Factors2021
- Author(s)
  Miyagi-Shiohira Chika、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 3 Pages: 454-454
- DOI
  10.3390/jcm10030454
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04412, KAKENHI-PROJECT-19K09051, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-21K19537
[Journal Article] Novel cell-permeable p38-MAPK inhibitor efficiently prevents porcine islet apoptosis and improves islet graft function.2020
- Author(s)
  Noguchi H, Miyagi-Shiohira C, Nakashima Y, Saitoh I, Watanabe M.
- Journal Title
  
  Am J Transplant.
  
  Volume: in press Issue: 5 Pages: 1296-1308
- DOI
  10.1111/ajt.15740
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-17H04412
[Journal Article] Preservation of pancreas in the University of Wisconsin solution supplemented with AP39 reduces reactive oxygen species production and improves islet graft function2020
- Author(s)
  Nishime Kai、Miyagi‐Shiohira Chika、Kuwae Kazuho、Tamaki Yoshihito、Yonaha Tasuku、Sakai‐Yonaha Mayuko、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  American Journal of Transplantation
  
  Volume: in press Issue: 8 Pages: 2698-2708
- DOI
  10.1111/ajt.16401
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-21K19537
[Journal Article] Kyoto probe-1 reveals phenotypic differences between mouse ES cells and iTS-P cells2020
- Author(s)
  Miyagi-Shiohira Chika、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 945-949
- DOI
  10.1038/s41598-020-75016-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09051, KAKENHI-PROJECT-20H03745
[Journal Article] Reduced glycemic variability and flexible graft function after islet transplantation: A case report2020
- Author(s)
  Nakamura Toshihiro、Fujikura Junji、Anazawa Takayuki、Ito Ryo、Ogura Masahito、Okajima Hideaki、Noguchi Hirofumi、Uemoto Shinji、Inagaki Nobuya
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 11 Issue: 6 Pages: 1677-1680
- DOI
  10.1111/jdi.13292
- NAID
  120006898127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03745
[Journal Article] Mutations in the C1 element of the insulin promoter lead to diabetic phenotypes in homozygous mice2020
- Author(s)
  Noguchi H, Miyagi-Shiohira C, Nakashima Y, Kinjo T, Saitoh I, Watanabe M
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 1-11
- DOI
  10.1038/s42003-020-1040-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08655, KAKENHI-PROJECT-17H04412, KAKENHI-PROJECT-20H03745
[Journal Article] Pancreas preservation in extracellular‐type p38 inhibitor‐containing solution improves islet yield for porcine islet isolation2020
- Author(s)
  Yonaha Tasuku、Miyagi‐Shiohira Chika、Kuwae Kazuho、Tamaki Yoshihito、Nishime Kai、Sakai‐Yonaha Mayuko、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Xenotransplantation
  
  Volume: 28 Issue: 2
- DOI
  10.1111/xen.12661
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04412, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-21K19537
[Journal Article] Pancreatic Islet Purification from Large Mammals and Humans Using a COBE 2991 Cell Processor versus Large Plastic Bottles2020
- Author(s)
  Noguchi Hirofumi
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 10 Issue: 1 Pages: 10-10
- DOI
  10.3390/jcm10010010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03745
[Journal Article] Drug-induced naive iPS cells exhibit better performance than primed iPS cells with respect to the ability to differentiate into pancreatic β-cell lineage2020
- Author(s)
  Kiyokawa Y, Sato M, Noguchi H, Inada E, Iwase Y, Kubota N, Sawami T, Terunuma M, Maeda T, Hayasaki H, Saitoh I
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 9 Issue: 9 Pages: 2838-2838
- DOI
  10.3390/jcm9092838
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06372, KAKENHI-PROJECT-20K10210, KAKENHI-PROJECT-18KK0258, KAKENHI-PROJECT-17H04412, KAKENHI-PROJECT-20H03745, KAKENHI-PROJECT-18K09839
[Journal Article] Excellent Islet Yields after 18-h Porcine Pancreas Preservation by Ductal Injection, Pancreas Preservation with MK Solution, Bottle Purification, and Islet Purification Using Iodixanol with UW Solution and Iodixanol with MK Solution.2019
- Author(s)
  Kuwae K, Miyagi-Shiohira C, Hamada E, Tamaki Y, Nishime K, Sakai M, Yonaha T, Makishi E, Saitoh I, Watanabe M, Noguchi H.
- Journal Title
  
  J Clin Med.
  
  Volume: 8(10). Issue: 10 Pages: 1561-1561
- DOI
  10.3390/jcm8101561
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-17H04412
[Journal Article] Repeated human deciduous tooth-derived dental pulp cell reprogramming factor transfection yields multipotent intermediate cells with enhanced iPS cell formation capability2019
- Author(s)
  Soda Miki、Saitoh Issei、Murakami Tomoya、Inada Emi、Iwase Yoko、Noguchi Hirofumi、Shibasaki Shinji、Kurosawa Mie、Sawami Tadashi、Terunuma Miho、Kubota Naoko、Terao Yutaka、Ohshima Hayato、Hayasaki Haruaki、Sato Masahiro
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 1490-1490
- DOI
  10.1038/s41598-018-37291-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09839, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-17H04366, KAKENHI-PROJECT-16K10436, KAKENHI-PROJECT-16K11810, KAKENHI-PROJECT-17K11956, KAKENHI-PROJECT-17K17318, KAKENHI-PROJECT-17K11953, KAKENHI-PROJECT-19K06372, KAKENHI-PROJECT-17K11957, KAKENHI-PROJECT-17H04412
[Journal Article] Regulation of c-Jun NH(2)-Terminal Kinase for Islet Transplantation.2019
- Author(s)
  Noguchi H.
- Journal Title
  
  J Clin Med.
  
  Volume: 8(11). Issue: 11 Pages: 1763-1763
- DOI
  10.3390/jcm8111763
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00769
[Journal Article] Identification of Proteins Differentially Expressed by Adipose-derived Mesenchymal Stem Cells Isolated from Immunodeficient Mice.2019
- Author(s)
  Nakashima Y, Nahar S, Miyagi-Shiohira C, Kinjo T, Kobayashi N, Kitamura S, Saitoh I, Watanabe M, Fujita J, Noguchi H
- Journal Title
  
  Int J Mol Sci
  
  Volume: 30 Issue: 11 Pages: 1-19
- DOI
  10.3390/ijms20112672
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08244, KAKENHI-PROJECT-19K09051, KAKENHI-PROJECT-18K08545, KAKENHI-PROJECT-17H04412
[Journal Article] A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Primary Cultured Cells and Subcultured Cells Using Mouse Adipose-Derived Mesenchymal Stem Cells2019
- Author(s)
  Nakashima Yoshiki、Nahar Saifun、Miyagi-Shiohira Chika、Kinjo Takao、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Fujita Jiro、Noguchi Hirofumi
- Journal Title
  
  Stem Cells International
  
  Volume: 2019 Pages: 1-97
- DOI
  10.1155/2019/7274057
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436, KAKENHI-PROJECT-19K09051, KAKENHI-PROJECT-17H04412
[Journal Article] A novel preservation solution containing a JNK inhibitory peptide efficiently improves islet yield for porcine islet isolation.2019
- Author(s)
  Noguchi H, Miyagi-Shiohira C, Nakashima Y, Ebi N, Hamada E, Tamaki Y, Kuwae K, Kitamura S, Kobayashi N, Saitoh I, Watanabe M
- Journal Title
  
  Transplantation.
  
  Volume: 103 Issue: 2 Pages: 344-352
- DOI
  10.1097/tp.0000000000002555
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08244, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436, KAKENHI-PROJECT-17H04412
[Journal Article] piggyBac Transposon-Based Immortalization of Human Deciduous Tooth Dental Pulp Cells with Multipotency and Non-Tumorigenic Potential.2019
- Author(s)
  Inada E, Saitoh I, Kubota N, Iwase Y, Kiyokawa Y, Shibasaki S, Noguchi H, Yamasaki Y, Sato M
- Journal Title
  
  International Journal of Molecular Science
  
  Volume: 20 Issue: 19 Pages: 4904-4904
- DOI
  10.3390/ijms20194904
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09839, KAKENHI-PROJECT-19K06372, KAKENHI-PROJECT-17K11957, KAKENHI-PROJECT-17H04412
[Journal Article] Induction of Expandable Tissue-Specific Progenitor Cells from Human Pancreatic Tissue through Transient Expression of Defined Factors2019
- Author(s)
  Noguchi Hirofumi、Miyagi-Shiohira Chika、Nakashima Yoshiki、Kinjo Takao、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Shapiro A. M. James、Kin Tatsuya
- Journal Title
  
  Molecular Therapy - Methods & Clinical Development
  
  Volume: 13 Pages: 243-252
- DOI
  10.1016/j.omtm.2019.01.011
- NAID
  120007004859
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436, KAKENHI-PROJECT-19K09051, KAKENHI-PROJECT-17H04412
[Journal Article] Adhesion characteristics of porcine pancreatic islets and exocrine tissue to coating materials2018
- Author(s)
  Nakashima Yoshiki、Miyagi-Shiohira Chika、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Islets
  
  Volume: 10 Issue: 3 Pages: e1460294-e1460294
- DOI
  10.1080/19382014.2018.1460294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Role of Egr1 on Pancreatic Endoderm Differentiation2018
- Author(s)
  Tsugata Takako、Nikoh Naruo、Kin Tatsuya、Miyagi-Shiohira Chika、Nakashima Yoshiki、Saitoh Issei、Noguchi Yasufumi、Ueki Hideo、Watanabe Masami、Kobayashi Naoya、Shapiro Andrew M. James、Noguchi Hirofumi
- Journal Title
  
  Cell Medicine
  
  Volume: 10 Pages: 215517901773317-215517901773317
- DOI
  10.1177/2155179017733177
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] A Comparison of the Preservation of Mouse Adipose Tissue-Derived Mesenchymal Stem Cells Using the University of Wisconsin Solution and Hank’s Balanced Salt Solution2018
- Author(s)
  Nahar Saifun、Nakashima Yoshiki、Miyagi-Shiohira Chika、Kinjo Takao、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi、Fujita Jiro
- Journal Title
  
  Stem Cells International
  
  Volume: 2018 Pages: 1-9
- DOI
  10.1155/2018/1625464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436
[Journal Article] A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of the Proteins Secreted by Human Adipose-Derived Mesenchymal Stem Cells2018
- Author(s)
  Nakashima Yoshiki、Nahar Saifun、Miyagi-Shiohira Chika、Kinjo Takao、Toyoda Zensei、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Fujita Jiro、Noguchi Hirofumi
- Journal Title
  
  Cell Transplantation
  
  Volume: 27 Issue: 10 Pages: 1469-1494
- DOI
  10.1177/0963689718795096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436
[Journal Article] Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA2018
- Author(s)
  Miyagi-Shiohira Chika、Nakashima Yoshiki、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 12341-12341
- DOI
  10.1038/s41598-018-30784-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10435, KAKENHI-PROJECT-16K10436
[Journal Article] Evaluation of Islet Purification Methods for Making a Continuous Density Gradient and Loading Tissue2018
- Author(s)
  Ebi Nana、Miyagi-Shiohira Chika、Hamada Eri、Tamaki Yoshihito、Masamoto Mariko、Makishi Erika、Nakashima Yoshiki、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Yasufumi、Kinjo Takao、Noguchi Hirofumi
- Journal Title
  
  Cell Medicine
  
  Volume: 10 Pages: 215517901773309-215517901773309
- DOI
  10.1177/2155179017733090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Cytokines in adipose-derived mesenchymal stem cells promote the healing of liver disease2018
- Author(s)
  Nahar Saifun、Nakashima Yoshiki、Miyagi-Shiohira Chika、Kinjo Takao、Toyoda Zensei、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi、Fujita Jiro
- Journal Title
  
  World Journal of Stem Cells
  
  Volume: 10 Issue: 11 Pages: 146-159
- DOI
  10.4252/wjsc.v10.i11.146
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436
[Journal Article] A Comparison of Proteins Expressed between Human and Mouse Adipose-Derived Mesenchymal Stem Cells by a Proteome Analysis through Liquid Chromatography with Tandem Mass Spectrometry2018
- Author(s)
  Nahar Saifun、Nakashima Yoshiki、Miyagi-Shiohira Chika、Kinjo Takao、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Hirofumi、Fujita Jiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3497-3497
- DOI
  10.3390/ijms19113497
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436
[Journal Article] The Healing Effect of Human Milk Fat Globule-EGF Factor 8 Protein (MFG-E8) in A Rat Model of Parkinson’s Disease2018
- Author(s)
  Nakashima Yoshiki、Miyagi-Shiohira Chika、Noguchi Hirofumi、Omasa Takeshi
- Journal Title
  
  Brain Sciences
  
  Volume: 8 Issue: 9 Pages: 167-167
- DOI
  10.3390/brainsci8090167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Induction of Expandable Adipose-Derived Mesenchymal Stem Cells from Aged Mesenchymal Stem Cells by a Synthetic Self-Replicating RNA.2018
- Author(s)
  Miyagi-Shiohira C, Nakashima Y, Kobayashi N, Kitamura S, Saitoh I, Watanabe M, Noguchi H
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 6 Issue: 11 Pages: 3489-3489
- DOI
  10.3390/ijms19113489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08244, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10435, KAKENHI-PROJECT-16K10436, KAKENHI-PROJECT-16K15689
[Journal Article] The Development of Cancer through the Transient Overexpression of Reprogramming Factors2018
- Author(s)
  Miyagi-Shiohira Chika、Nakashima Yoshiki、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Noguchi Yasufumi、Kinjo Takao、Noguchi Hirofumi
- Journal Title
  
  Cell Medicine
  
  Volume: 10 Pages: 215517901773317-215517901773317
- DOI
  10.1177/2155179017733172
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10435
[Journal Article] Induced Tissue-Specific Stem Cells and Epigenetic Memory in Induced Pluripotent Stem Cells.2018
- Author(s)
  Noguchi H, Miyagi-Shiohira C, Nakashima Y.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21;19(4) Issue: 4 Pages: 930-930
- DOI
  10.3390/ijms19040930
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10435, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404
[Journal Article] A Comparison of Pancreatic Islet Purification using Iodixanol with University of Wisconsin Solution and with Na-Lactobionate and Histidine Solution2018
- Author(s)
  Nakashima Yoshiki、Miyagi-Shiohira Chika、Ebi Nana、Hamada Eri、Tamaki Yoshihito、Kuwae Kazuho、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Kinjo Takao、Noguchi Hirofumi
- Journal Title
  
  Cell Medicine
  
  Volume: 10 Pages: 215517901877507-215517901877507
- DOI
  10.1177/2155179018775071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Atorvastatin Inhibits the HIF1α-PPAR Axis, Which Is Essential for Maintaining the Function of Human Induced Pluripotent Stem Cells2018
- Author(s)
  Nakashima Yoshiki、Miyagi-Shiohira Chika、Noguchi Hirofumi、Omasa Takeshi
- Journal Title
  
  Molecular Therapy
  
  Volume: 26 Issue: 7 Pages: 1715-1734
- DOI
  10.1016/j.ymthe.2018.06.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10436
[Journal Article] A Comparison of Pancreatic Islet Purification using Iodixanol with University of Wisconsin and with Na-Lactobionate and Histidine Solutions.2018
- Author(s)
  Nakashima Y, Miyagi-Shiohira C, Ebi N, Hamada E, Tamaki Y, Kuwae K, Kobayashi N, Saitoh I, Watanabe M, Kinjo T, Noguchi H.
- Journal Title
  
  Cell Med
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10435
[Journal Article] Long-term Cryopreservation of Human and other Mammalian Cells at -80℃ for 8 Years2018
- Author(s)
  Yoshitaka Miyamoto, Masashi Ikeuchi, Hirofumi Noguchi, Shuji Hayashi
- Journal Title
  
  Cell Medicine
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03039
[Journal Article] Modified cell-permeable JNK inhibitors efficiently prevents islet apoptosis and improves the outcome of islet transplantation.2018
- Author(s)
  Noguchi H, Miyagi-Shiohira C, Nakashima Y, Ebi N, Hamada E, Tamaki Y, Kuwae K, Kobayashi N, Saitoh I, Watanabe M.
- Journal Title
  
  Sci Rep.
  
  Volume: 8(1) Issue: 1 Pages: 11082-11082
- DOI
  10.1038/s41598-018-29481-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-17H04412, KAKENHI-PROJECT-16K10436
[Journal Article] Adhesion characteristics of porcine pancreatic islets and exocrine tissue to coating materials.2018
- Author(s)
  Nakashima Y, Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi H.
- Journal Title
  
  Islets
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10435
[Journal Article] Comparison Between Modified Extracellular-Type Trehalose-Containing Kyoto Solution and University of Wisconsin Solution in 18-Hour Pancreas Preservation for Islet Transplantation.2018
- Author(s)
  Hamada E, Ebi N, Miyagi-Shiohira C, Tamaki Y, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Kinjo T, Noguchi H.
- Journal Title
  
  Pancreas.
  
  Volume: 47(7) Issue: 7 Pages: e46-e47
- DOI
  10.1097/mpa.0000000000001104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404
[Journal Article] A Liquid Chromatography with Tandem Mass Spectrometry-Based Proteomic Analysis of Cells Cultured in DMEM 10% FBS and Chemically Defined Medium Using Human Adipose-Derived Mesenchymal Stem Cells2018
- Author(s)
  Nakashima Yoshiki、Nahar Saifun、Miyagi-Shiohira Chika、Kinjo Takao、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Fujita Jiro、Noguchi Hirofumi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 7 Pages: 2042-2042
- DOI
  10.3390/ijms19072042
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08545, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16K10436
[Journal Article] Comparison of Tissue Loading Before and After the Creation of a Continuous Density Gradient in Porcine Islet Purification2018
- Author(s)
  Miyagi-Shiohira Chika、Nakashima Yoshiki、Ebi Nana、Hamada Eri、Tamaki Yoshihito、Kuwae Kazuho、Kobayashi Naoya、Saitoh Issei、Watanabe Masami、Kinjo Takao、Noguchi Hirofumi
- Journal Title
  
  Cell Medicine
  
  Volume: 10 Pages: 215517901878134-215517901878134
- DOI
  10.1177/2155179018781343
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Long-term Cryopreservation of Human and other Mammalian Cells at ?80 °C for 8 Years2018
- Author(s)
  Miyamoto Yoshitaka、Ikeuchi Masashi、Noguchi Hirofumi、Hayashi Shuji
- Journal Title
  
  Cell Medicine
  
  Volume: 10 Pages: 215517901773314-215517901773314
- DOI
  10.1177/2155179017733148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] A proteome analysis of pig pancreatic islets and exocrine tissue by liquid chromatography with tandem mass spectrometry.2017
- Author(s)
  Nakashima Y, Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi H.
- Journal Title
  
  Islets
  
  Volume: Nov2;9(6) Pages: 159-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10435
[Journal Article] Exogenous DKK-3/REIC inhibits Wnt/β-catenin signaling and cell proliferation in human kidney cancer KPK12017
- Author(s)
  Xu Jiaqi、Sadahira Takuya、Kinoshita Rie、Li ShunAi、Huang Peng、Wada Koichiro、Araki Motoo、Ochiai Kazuhiko、Noguchi Hirofumi、Sakaguchi Masakiyo、Nasu Yasutomo、Watanabe Masami
- Journal Title
  
  Oncology Letters
  
  Volume: 14 Pages: 5638-5642
- DOI
  10.3892/ol.2017.6833
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11138, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-17H03577, KAKENHI-PROJECT-16K18440
[Journal Article] Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers2017
- Author(s)
  Tomoya Murakami, Issei Saitoh, Masahiro Sato, Emi Inada, Miki Soda, Masataka Oda, Hisanori Domone, Yoko Iwase, Tadashi Sawami, Kazunari Matsueda, Yutaka Terao, Hayato Ohshima, Hirofumi Noguchi, Haruaki Hayasaki
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 印刷中
- Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26463109
[Journal Article] Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers.2017
- Author(s)
  Murakami T, Saitoh I, Sato M, Inada E, Soda M, Oda M, Domon H, Iwase Y, Sawami T, Matsueda K, Terao Y, Ohshima H, Noguchi H, Hayasaki H
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 81 Pages: 110-120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11810
[Journal Article] 心停止下膵島移植に向けた持続冷却灌流保存法による膵臓保存2017
- Author(s)
  圷尚武、丸山通広、大月和宣、石田健倫、齋藤友永、西郷健一、長谷川正行、青山博道、剣持敬、野口洋文
- Journal Title
  
  Organ Biology
  
  Volume: 24 Pages: 55-59
- NAID
  130006035076
- Data Source
  KAKENHI-PROJECT-26461933
[Journal Article] Role of EGR1 on pancreatic endoderm differentiation.2017
- Author(s)
  Tsugata T, Nikoh N, Kin T, Miyagi-Shiohira C, Nakashima Y, Saitoh I, Noguchi Y, Ueki H, Watanabe M, Kobayashi N, Shapiro AMJ, Noguchi H.
- Journal Title
  
  Cell Med
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10435
[Journal Article] RCAN-11R peptide provides immunosuppression for fully mismatched islet allografts in mice.2017
- Author(s)
  Noguchi H, Sugimoto K, Miyagi-Shiohira C, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y.
- Journal Title
  
  Scientific Reprots.
  
  Volume: - Issue: 1 Pages: 3043-3043
- DOI
  10.1038/s41598-017-02934-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10435, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404
[Journal Article] Long-term Cryopreservation of Human and Mammalian Cell at -80℃ for 8 years2017
- Author(s)
  Miyamoto Y, Ikeuchi M, Noguchi H, Hayashi S
- Journal Title
  
  Cell Medicine
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03039
[Journal Article] Evaluation of islet purification methods to make continuous density gradient and to load tissue.2017
- Author(s)
  Ebi N, Miyagi-Shiohira C, Hamada E, Tamaki Y, Masamoto M, Makishi E, Nakashima Y, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Kinjo T Noguchi H.
- Journal Title
  
  Cell Med
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10435
[Journal Article] Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers2017
- Author(s)
  Tomoya Murakami, Issei Saitoh, Masahiro Sato, Emi Inada, Miki Soda, Masataka Oda, Hisanori Domone, Yoko Iwase, Tadashi Sawami, Kazunari Matsueda, Yutaka Terao, Hayato Ohshima, Hirofumi Noguchi, Haruaki Hayasaki
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670883
[Journal Article] Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers2017
- Author(s)
  Tomoya Murakami, Issei Saitoh, Masahiro Sato, Emi Inada, Miki Soda, Masataka Oda, Hisanori Domone, Yoko Iwase, Tadashi Sawami, Kazunari Matsueda, Yutaka Terao, Hayato Ohshima, Hirofumi Noguchi, Haruaki Hayasaki
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25293418
[Journal Article] A proteome analysis of pig pancreatic islets and exocrine tissue by liquid chromatography with tandem mass spectrometry.2017
- Author(s)
  Nakashima Y, Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi H.
- Journal Title
  
  Islets.
  
  Volume: 9(6) Issue: 6 Pages: 159-176
- DOI
  10.1080/19382014.2017.1389826
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404
[Journal Article] Isolation and characterization of lymphoid enhancer factor-1-positive deciduous dental pulp stem-like cells after transfection with a piggyBac vector containing LEF1 promoter-driven selection markers.2017
- Author(s)
  Murakami T, Saitoh I, Sato M, Inada E, Soda M, Oda M, Domon H, Iwase Y, Sawami T, Matsueda K, Terao Y, Ohshima H, Noguchi H, Hayasaki H
- Journal Title
  
  Archives of Oral Biology
  
  Volume: 81 Pages: 110-120
- DOI
  10.1016/j.archoralbio.2017.04.033
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15J03924, KAKENHI-PROJECT-16K11439, KAKENHI-PROJECT-17K11953, KAKENHI-PROJECT-17K17318, KAKENHI-PROJECT-17H00769, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-17H04366, KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-26463111, KAKENHI-PROJECT-15H05017
[Journal Article] Evaluation of Serum-Free, Xeno-Free Cryopreservation Solutions for Human Adipose-Derived Mesenchymal Stem Cells.2016
- Author(s)
  Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 9 Issue: 1-2 Pages: 15-20
- DOI
  10.3727/215517916x693122
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Enhanced Adipogenic Differentiation of Human Adipose-Derived Stem Cells in an In Vitro Microenvironment: The Preparation of Adipose-Like Microtissues Using a Three-Dimensional Culture2016
- Author(s)
  Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S
- Journal Title
  
  Cell Medicine
  
  Volume: 9(1-2) Issue: 1-2 Pages: 35-44
- DOI
  10.3727/215517916x693096
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03039, KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-16H02094, KAKENHI-PROJECT-16K12921
[Journal Article] Comparison of Purification Solutions With Different Osmolality for Porcine Islet Purification.2016
- Author(s)
  Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 9 Issue: 1-2 Pages: 53-59
- DOI
  10.3727/215517916x693140
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Enhanced Adipogenic Differentiation of Human Adipose-derived Stem Cells in an In Vitro Microenvironment: The Preparation of Adipose-like Microtissues using a Three-dimensional Culture2016
- Author(s)
  Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S
- Journal Title
  
  Cell Medicine
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25560248
[Journal Article] Enhanced Adipogenic Differentiation of Human Adipose-derived Stem Cells in an In Vitro Microenvironment: The Preparation of Adipose-like Microtissues using a Three-dimensional Culture2016
- Author(s)
  Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S
- Journal Title
  
  Cell Medicine
  
  Volume: -
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H03039
[Journal Article] The Evaluation of Islet Purification Methods That Use Large Bottles to Create a Continuous Density Gradient.2016
- Author(s)
  Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 9 Issue: 1-2 Pages: 45-51
- DOI
  10.3727/215517916x693131
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404
[Journal Article] Evaluation of Serum-Free, Xeno-Free Cryopreservation Solutions for Human Adipose-Derived Mesenchymal Stem Cells.2016
- Author(s)
  Miyagi-Shiohira C, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 9 Pages: 15-20
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10435
[Journal Article] Tissue-Specific Stem Cells Obtained by Reprogramming of Non-Obese Diabetic (NOD) Mouse-Derived Pancreatic Cells Confer Insulin Production in Response to Glucose.2016
- Author(s)
  Saitoh I, Sato M, Soda M, Inada E, Iwase Y, Murakami T, Ohshima H, Hayasaki H, Noguchi H.
- Journal Title
  
  PLoS One.
  
  Volume: １１ Issue: 9 Pages: e0163580-e0163580
- DOI
  10.1371/journal.pone.0163580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05404, KAKENHI-PROJECT-15J03924, KAKENHI-PROJECT-25463192, KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-16K11810
[Journal Article] Potential factors for the differentiation of ES/iPS cells into insulin-producing cells.2015
- Author(s)
  Tsugata T, Nikoh N, Kin T, Saitoh I, Noguchi Y, Ueki H, Watanabe M, Shapiro AMJ, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 7 Issue: 2 Pages: 83-93
- DOI
  10.3727/215517914x685178
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-26670590
[Journal Article] Choice of feeders is important when first establishing iPSCs derived from primarily cultured human deciduous tooth dental pulp cells.2015
- Author(s)
  Saitoh I, Inada E, Iwase Y, Noguchi H, Murakami T, Soda M, Kubota N, Hasegawa H, Akasaka E, Matsumoto Y, Oka K, Yamasaki Y, Hayasaki H, Sato M
- Journal Title
  
  Cell Medicine
  
  Volume: 8 Issue: 1-2 Pages: 9-23
- DOI
  10.3727/215517915x689038
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-25463192, KAKENHI-PROJECT-15K15762, KAKENHI-PROJECT-15J03924, KAKENHI-PROJECT-26670590, KAKENHI-PROJECT-25293418
[Journal Article] Spheroid Formation and Evaluation of Hepatic Cells in a Three-Dimensional Culture Device2015
- Author(s)
  Miyamoto Y, Ikeuchi M, Noguchi H, Yagi T, Hayashi S
- Journal Title
  
  Cell Medicine
  
  Volume: 8(1-2) Issue: 1-2 Pages: 47-56
- DOI
  10.3727/215517915x689056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H03039, KAKENHI-PROJECT-25560248, KAKENHI-PROJECT-26670590
[Journal Article] Cryopreservation of Adipose-Derived Mesenchymal Stem Cells.2015
- Author(s)
  Miyagi-Shiohira C, Kurima K, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 8 Issue: 1-2 Pages: 3-7
- DOI
  10.3727/215517915x689100
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670590
[Journal Article] Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection.2015
- Author(s)
  Noguchi H, Saitoh I, Tsugata T, Kataoka H, Watanabe M, Noguchi Y.
- Journal Title
  
  Cell Death Differ.
  
  Volume: 22 Issue: 1 Pages: 145-155
- DOI
  10.1038/cdd.2014.132
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-26670590
[Journal Article] Islet culture/preservation before islet transplantation.2015
- Author(s)
  Noguchi H, Miyagi-Shiohira C, Kurima K, Kobayashi N, Saitoh I, Watanabe M, Noguchi Y, Matsushita M.
- Journal Title
  
  Cell Med.
  
  Volume: 8 Issue: 1-2 Pages: 25-29
- DOI
  10.3727/215517915x689047
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26670590
[Journal Article] Three-Dimensional in vitro Hepatic Constructs Formed Using Combinatorial Tapered Stencil for Cluster Culture (TASCL) Device2015
- Author(s)
  Y. Miyamoto, M. Ikeuchi, H. Noguchi, T. Yagi, S. Hayashi
- Journal Title
  
  Cell Medicine
  
  Volume: 7 Issue: 2 Pages: 67-74
- DOI
  10.3727/215517914x685187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22220008, KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-25560248, KAKENHI-PROJECT-26670590
[Journal Article] Islet Purification for Clinical Islet Transplantation.2014
- Author(s)
  Noguchi H
- Journal Title
  
  Current Tissue Engineering.
  
  Volume: 3 Issue: 1 Pages: 34-38
- DOI
  10.2174/2211542002666131230234825
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-26670590
[Journal Article] Establishment of a pancreatic stem cell line from fibroblast-derived induced pluripotent stem cells.2014
- Author(s)
  Kuise T, Noguchi H, Tazawa H, Kawai T, Iwamuro M, Saitoh I, Kataoka HU, Watanabe M, Noguchi Y, Fujiwara T.
- Journal Title
  
  Biomed Eng Online.
  
  Volume: 13 Issue: 1
- DOI
  10.1186/1475-925x-13-64
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-26670590
[Journal Article] Novel positively charged nanoparticle labeling for in vivo imaging of adipose tissue-derived stem cells.2014
- Author(s)
  Yukawa H, Nakagawa S, Yoshizumi Y, Watanabe M, Saito H, Miyamoto Y, Noguchi H, Oishi K, Ono K, Sawada M, Kato I, Onoshima D, Obayashi M, Hayashi Y, Kaji N, Ishikawa T, Hayashi S, Baba Y.
- Journal Title
  
  PLoS One.
  
  Volume: 9 Issue: 11 Pages: e110142-e110142
- DOI
  10.1371/journal.pone.0110142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-24681027, KAKENHI-PROJECT-26670590, KAKENHI-PROJECT-26750146
[Journal Article] A new method for generating insulin-secreting cells from human pancreatic epithelial cells after islet isolation transformed by NeuroD1.2014
- Author(s)
  Shimoda M, Chen S, Noguchi H, Takita M, Sugimoto K, Itoh T, Chujo D, Iwahashi S, Naziruddin B, Levy MF, Matsumoto S, Grayburn PA.
- Journal Title
  
  Hum Gene Ther Methods.
  
  Volume: 25 Issue: 3 Pages: 206-219
- DOI
  10.1089/hgtb.2013.122
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-26670590
[Journal Article] Generation of Functional Insulin-Producing Cells From Mouse Embryonic Stem Cells Through 804G Cell-Derived Extracellular Matrix and Protein Transduction of Transcription Factors.2014
- Author(s)
  Kaitsuka T, Noguchi H, Shiraki N, Kubo T, Wei FY, Hakim F, Kume S, Tomizawa K.
- Journal Title
  
  Stem Cells Transl Med.
  
  Volume: 3 Issue: 1 Pages: 114-127
- DOI
  10.5966/sctm.2013-0075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-24790217, KAKENHI-PROJECT-25860753
[Journal Article] Comparison of new preservation solution, HN-1, and University of Wisconsin solution in pancreas preservation for porcine islet isolation2013
- Author(s)
  Akihiro K, Noguchi H, Kuise T, Nakatsuka A, Hirota D, Kataoka H, Kawai T, Inoue K, Imagawa N, Saitoh I, Noguchi Y, Watanabe M, Wada J, Fujiwara T
- Journal Title
  
  Cell Medicine
  
  Volume: 6 Issue: 1-2 Pages: 3-8
- DOI
  10.3727/215517913x674171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-24390316
[Journal Article] Observation of positively-charged magnetic nanoparticles inside HepG2 spheroids using electron microscopy.2013
- Author(s)
  MiyamotoY, Koshidaka Y, Noguchi H, Oishi K, Saito H, Yukawa H, Kaji N, Ikeya T, Suzuki S, Iwata H, Baba Y, Murase K, Hayashi S.
- Journal Title
  
  Cell Med.
  
  Volume: 5 Issue: 2-3 Pages: 89-96
- DOI
  10.3727/215517913x666530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Maintenance of viability and function of rat islets with the use of ROCK inhibitor Y276322013
- Author(s)
  Kubota Y, Noguchi H, Seita M, Yuasa T, Sasamoto H, Nakaji S, Okitsu T, Fujiwara T, Kobayashi N
- Journal Title
  
  Cell Medicine
  
  Volume: 6 Issue: 1-2 Pages: 15-23
- DOI
  10.3727/215517913x674199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-24390316
[Journal Article] Cancer stem cell-like characteristics of a CD133(+) subpopulation in the J82 human bladder cancer cell line.2013
- Author(s)
  Huang P, Watanabe M, Kaku H, Ueki H, Noguchi H, Sugimoto M, Hirata T, Yamada H, Takei K, Zheng S, Xu K, Nasu Y, Fujii Y, Liu C, Kumon H.
- Journal Title
  
  Mol Clin Oncol.
  
  Volume: 1 Issue: 1 Pages: 180-184
- DOI
  10.3892/mco.2012.29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] In vivo imaging of transplanted islets labeled with a novel cationic nanoparticle2013
- Author(s)
  Oishi K, Miyamoto Y, Saito H, Murase K, Ono　K, Sawada M, Watanabe M, Noguchi Y, Fujiwara T, Hayashi S, Noguchi H
- Journal Title
  
  PLOS ONE
  
  Volume: 8(2) Issue: 2 Pages: e57046-e57046
- DOI
  10.1371/journal.pone.0057046
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23650190, KAKENHI-PROJECT-24390316
[Journal Article] ER stress and  cell pathogenesis of type 1 and type 2 diabetes and islet transplantation.2013
- Author(s)
  Kataoka HU, Noguchi H.
- Journal Title
  
  Cell Med.
  
  Volume: 5 Issue: 2-3 Pages: 53-57
- DOI
  10.3727/215517913x666512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Comparison of incubation solutions prior to islet purification in porcine islet isolation.2013
- Author(s)
  Kawai T, Noguchi H, Kuise T, Nakatsuka A, Katayama A, Imagawa N, Kataoka HU, Saitoh I, Noguchi Y, Watanabe M, Fujiwara T.
- Journal Title
  
  Cell Med.
  
  Volume: 6 Issue: 1-2 Pages: 9-14
- DOI
  10.3727/215517913x674180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Development of Canine Models of Type 1 Diabetes with Partial Pancreatectomy and the Administration of STZ2013
- Author(s)
  Seita M, Noguchi H, Kubota Y, Kawamoto H, Nakaji S, Kobayashi N, Fujiwara T
- Journal Title
  
  Cell Medicine
  
  Volume: 6 Issue: 1-2 Pages: 25-31
- DOI
  10.3727/215517913x674289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-24390316
[Journal Article] Culture conditions for mouse pancreatic stem cells2013
- Author(s)
  Noguchi H, Saitoh I, Kataoka H, Watanabe M, Noguchi Y, Fujiwara T
- Journal Title
  
  Cell Medicine
  
  Volume: 5 Issue: 2-3 Pages: 63-68
- DOI
  10.3727/215517913x666495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-24390316
[Journal Article] Isolation efficiency of mouse pancreatic stem cells is age-dependent2013
- Author(s)
  Takashi K, Noguchi H, Saitoh I, Kataoka H, Watanabe M, Noguchi Y, Fujiwara T
- Journal Title
  
  Cell Medicine
  
  Volume: 5 Issue: 2-3 Pages: 69-73
- DOI
  10.3727/215517913x666503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-24390316
[Journal Article] STO feeder cells are useful for propagation of primarily cultured human deciduous dental pulp cells in view of elimination of contaminated bacteria and promotion of cellular outgrowth.2013
- Author(s)
  Murakami T, Saitoh I, Inada E, Kurosawa M, Iwase Y, Noguchi H, Terao Y, Yamasaki Y, Hayasaki H, Sato M
- Journal Title
  
  Cell Medicine
  
  Volume: 7 Issue: 1-2 Pages: 75-81
- DOI
  10.3727/215517913x674234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-24501317, KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-25293418, KAKENHI-PROJECT-25463192
[Journal Article] Controlled expansion of mammalian cell populations by reversible immortalization.2013
- Author(s)
  Noguchi H, Kobayashi N.
- Journal Title
  
  J Biotechnol Biomater
  
  Volume: 3 Issue: 02 Pages: 158-158
- DOI
  10.4172/2155-952x.1000158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Generation of a set of mouse STO feeder cell lines that confer resistance to several types of selective drugs2012
- Author(s)
  Saitoh I, Sato M, Iwase Y, Akasaka E, Yamasaki Y, Noguchi H
- Journal Title
  
  Cell Medicine
  
  Volume: 3(1) Issue: 1-3 Pages: 97-102
- DOI
  10.3727/215517912x639414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592892, KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-23792364, KAKENHI-PROJECT-23792439, KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-24580411
[Journal Article] Adverse events in clinical islet transplantation : one institutional experience.2012
- Author(s)
  Takita M, Matsumoto S, Noguchi H, Shiuoda M, Ikemoto T, Chujo D, Tamura Y, Olsen GS, Naziruddin B, Purcell K, Onaca N, Levy MF.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 547-551
- DOI
  10.3727/096368911x605466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Cryopreservation of human adipose tissue-derived stem/progenitor cells using the silk protein sericin.2012
- Author(s)
  Miyamoto Y, Oishi K, Yukawa H, Noguchi H, Sasaki M, Iwata H, Hayashi S.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 617-622
- DOI
  10.3727/096368911x605556
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Fresh islets are more effective for islet transplantation than cultured islets. Cell2012
- Author(s)
  Noguchi H, Naziruddin B, Jackson A, Shimoda H, Ikemoto T, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy HF, Matsumoto S.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 517-523
- DOI
  10.3727/096368911x605439
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Differentiation of mouse pancreatic stem cells into insulin-producing cells by recombinant sendai virus-mediated gene transfer technology2012
- Author(s)
  H. Yukawa, et al.
- Journal Title
  
  Cell Medicine
  
  Volume: 3 Issue: 1-3 Pages: 51-61
- DOI
  10.3727/215517912x639487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24241050, KAKENHI-PROJECT-24390316
[Journal Article] Transplantation of osteogenically differentiated mouse iPS cells for bone repair.2012
- Author(s)
  Hayashi T, Misawa H, Nakahara H, Noguchi H, Yoshida A, Kobayashi N, Tanaka M, Ozaki T.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 591-600
- DOI
  10.3727/096368911x605529
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Cryopreservation of Induced Pluripotent Stem Cells.2012
- Author(s)
  Miyamoto Y, Noguchi H, Yukawa H, Oishi K, Matsushita K, Iwata H, Hayashi S.
- Journal Title
  
  Cell Med.
  
  Volume: 3 Issue: 1-3 Pages: 89-95
- DOI
  10.3727/215517912x639405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Secretory Unit of Islet Transplant Objects (SUITQ) Index Can Predict Severity of Hypoglycemic Episodes in Clinical Islet Cell Transplantation.2012
- Author(s)
  Takita M, Matsumoto S, Qin H, Noguchi H, Shimoda M, Chujo D, Itoh T, Sugimoto K, Onaca N, Naziruddin B, Levy MF.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 1 Pages: 91-98
- DOI
  10.3727/096368911x580617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Comparison of ulinastatin, gabexate mesilate, and nafamostat mesilate in preservation solution for islet isolation.2012
- Author(s)
  Noguchi H, Naziruddin B, Jackson A, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Ueda M, Okitsu T, Iwanaga Y, Nagata H, Liu X, Kamiya H, Onaca N, Levy MF, Matsumoto S.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 509-516
- DOI
  10.3727/096368911x605420
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] A novel gene expression system for detecting viable bladder cancer cells2012
- Author(s)
  Hideo Ueki, et al
- Journal Title
  
  International journal of oncology
  
  Volume: 41 Pages: 135-140
- DOI
  10.3892/ijo.2012.1417
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501013, KAKENHI-PROJECT-22616004, KAKENHI-PROJECT-23370089, KAKENHI-PROJECT-23659213, KAKENHI-PROJECT-24390316, KAKENHI-PROJECT-24780313
[Journal Article] Islet purification method using large bottles effectively achieves high islet yield from pig pancreas.2012
- Author(s)
  Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 501-508
- DOI
  10.3727/096368911x605411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Monitoring transplanted adipose tissue-derived stem cells combined with heparin in the liver by fluorescence imaging using quantum dots2012
- Author(s)
  Hiroshi Yukawa, et al.
- Journal Title
  
  Biomaterials
  
  Volume: 33 Issue: 7 Pages: 2177-2186
- DOI
  10.1016/j.biomaterials.2011.12.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24241050, KAKENHI-PROJECT-24390316
[Journal Article] Novel positive-charged nanoparticles for efficient magnetic resonance imaging of islet transplantation.2012
- Author(s)
  Oishi K, Noguchi H, Saito H, Yukawa H, Miyamoto Y, Ono K, Murase K, Sawada M, Hayashi S.
- Journal Title
  
  Cell Med.
  
  Volume: 3 Issue: 1-3 Pages: 43-49
- DOI
  10.3727/215517912x639397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Preclinical biodistribution and safety study of reduced expression in immortalized cells/Dickkopf-3-encoding adenoviral vector for prostate cancer gene therapy2012
- Author(s)
  Sugimoto M., Watanabe M., Kaku H., Li SA., Noguchi H., Ueki H., Sakaguchi M., Huh NH., Nasu Y., Kumon H
- Journal Title
  
  Oncol Rep
  
  Volume: 28巻 Issue: 5 Pages: 1645-1652
- DOI
  10.3892/or.2012.2001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23390382, KAKENHI-PROJECT-24390316, KAKENHI-PUBLICLY-24117711
[Journal Article] Improvement of porcine islet isolation by inhibition of trypsin activity during pancreas preservation and digestion using α-antitrypsin.2012
- Author(s)
  Shimoda M, Noguchi H, Fujita Y, Takita M, Ikemoto T, Chujo D, Naziruddin B, Levy MF, Kobayashi N, Grayburn PA, Matsumoto S.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 465-471
- DOI
  10.3727/096368911x605376
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Evaluation of osmolality of density gradient for human islet purification.2012
- Author(s)
  Noguchi H, Naziruddin B, Shimoda M, Fujita Y, Chujo D, Takita M, Peng H, Sugimoto K, Itoh T, Kobayashi N, Onaca N, Levy MF, Matsumoto S.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 493-500
- DOI
  10.3727/096368911x605402
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Improved pancreatic islet isolation outcome in autologous transplantation for chronic pancreatitis.2012
- Author(s)
  Naziruddin B, Matsumoto S, Noguchi H, Takita M, Shimoda M, Fujita Y, Chujo D, Tate C, Onaca N, Lamont J, Kobayashi N, Levy MF.
- Journal Title
  
  Cell Transplant.
  
  Volume: 21 Issue: 2-3 Pages: 553-558
- DOI
  10.3727/096368911x605475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] A combined continuous density/osmolality gradient for supplemental purification of human islets.2012
- Author(s)
  Noguchi H, Naziruddin B, Shimoda M, Chujo D, Takita M, Sugimoto K, Itoh T, Onaca N, Levy MF, Matsumoto S.
- Journal Title
  
  Cell Med.
  
  Volume: 3 Issue: 1-3 Pages: 33-41
- DOI
  10.3727/215517912x639388
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390316
[Journal Article] Attenuation of murine GVHD by a tea polyphenol2012
- Author(s)
  Kanamune, J., Iwanaga, Y., Kina, T., Noguchi, H., Matsumura, K., Uemoto, S., Hyon, S-H.
- Journal Title
  
  Cell Transplantation
  
  Volume: (In press) Issue: 5 Pages: 909-918
- DOI
  10.3727/096368911x623934
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591636, KAKENHI-PROJECT-24390316
[Patent] ヒト膵臓組織特異的幹/前駆細部の人工作製方法2021
- Inventor(s)
  野口洋文
- Industrial Property Rights Holder
  国立大学法人琉球大学
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Acquisition Date
  2023
- Data Source
  KAKENHI-PROJECT-21K19537
[Patent] ヒト組織特異的幹／前駆細胞の人工作製方法2018
- Inventor(s)
  野口洋文、潮平知佳、中島義基
- Industrial Property Rights Holder
  野口洋文、潮平知佳、中島義基
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Acquisition Date
  2018
- Data Source
  KAKENHI-PROJECT-16K10436
[Patent] 分化コントロール化合物を用いて造腫瘍性を持つおそれのある未分化iPS細胞等の混入を除去する方法2018
- Inventor(s)
  中島義基、大政健史、野口洋文、潮平知佳
- Industrial Property Rights Holder
  中島義基、大政健史、野口洋文、潮平知佳
- Industrial Property Rights Type
  特許
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-16K10435
[Presentation] Novel cell-permeable inhibitor of p38 MAPK improves islet graft function2021
- Author(s)
  Hirofumi Noguchi
- Organizer
  Asian Pancreas and Islet Transplant Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03745
[Presentation] 分子ロボティクスを用いた分子人工膵島細胞開発の現状と倫理的課2020
- Author(s)
  小長谷明彦, 河原直人, 野口洋文, 豊田太郎, 池田将, 湯川博, 川又生吹, 柳澤実穂, 梅田民樹, 小野喜志雄
- Organizer
  日本臨床試験学会
- Data Source
  KAKENHI-PROJECT-17H00769
[Presentation] Modified Cell-Permeable JNK Inhibitors Effciently Prevent Islet Apoptosis2019
- Author(s)
  Hirofumi Noguchi
- Organizer
  The 1st Congress of Asian Pancreas and Islet Transplant Association
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] 琉球大学での再生医療2019
- Author(s)
  野口洋文
- Organizer
  平成30年度沖縄力発見創造事業　企業誘致促進プログラム（再生医療関連）
- Invited
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] 膵島移植・再生医療の現状と展望2019
- Author(s)
  野口洋文
- Organizer
  '19先端医学研究交流セミナー in Okinawa
- Invited
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] Modified Cell-Permeable JNK Inhibitors Effciently Prevent Islet Apoptosis2019
- Author(s)
  Hirofumi Noguchi
- Organizer
  The 1st Congress of Asian Pancreas and Islet Transplant Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10436
[Presentation] 糖尿病薬の可能性～膵島移植の話題も含めて～2019
- Author(s)
  野口洋文
- Organizer
  Diabetes Researcher’s Forum 2019
- Invited
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] 産業化へ向けた膵島分離技術の改変2019
- Author(s)
  野口洋文
- Organizer
  委託共同研究成果発表シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] 膵島移植・再生療法の現状と展望2018
- Author(s)
  野口洋文
- Organizer
  人工知能学会合同研究会2018
- Invited
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] 膵島分離におけるボトル純化法の技術改変2018
- Author(s)
  野口洋文
- Organizer
  第45回日本膵・膵島移植研究会
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] 細胞加工施設（CPC）を利用した再生医療について2018
- Author(s)
  野口洋文
- Organizer
  第15回泌尿器科再建再生研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05404
[Presentation] －80℃下における細胞の長期凍結保存: 保存温度が細胞に与える影響2017
- Author(s)
  宮本義孝、池内真志、野口洋文、生田幸士、林衆治
- Organizer
  第69回日本生物工学会大会, 東京
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] 三次元培養によるヒト脂肪由来幹細胞からマイクロティッシュの作製2017
- Author(s)
  宮本義孝、池内真志、野口洋文、八木透、生田幸士、林衆治
- Organizer
  第16回日本再生医療学会総会
- Place of Presentation
  仙台国際センター, 宮城
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] Hypothermic machine perfusion preservation of pancreas for islet transplantation in non-heart-beating canine donor model2017
- Author(s)
  Akutsu N, Ishida T, Maruyama M, Otsuki K, Saitoh T, Saigo K, M, Aoyama H, Kenmochi T, Noguchi H
- Organizer
  IPITA 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461933
[Presentation] Differentiation evaluation in long-term cryopreserved human adipose tissue-derived stem/progenitor cells at －80°C2017
- Author(s)
  Yoshitaka Miyamoto, Masashi Ikeuchi, Hirofumi Noguchi, Shuji Hayashi
- Organizer
  第44回日本低温医学会総会, 千葉
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] 培養デバイス TASCL を用いたヒト脂肪様細胞組織体の創製2017
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  シンポジウム：細胞アッセイ技術の現状と将来
- Place of Presentation
  東京大学生産技術研究所コンベンションホール, 東京
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] －80℃でのヒト脂肪組織由来幹細胞の長期凍結保存（8年間）2017
- Author(s)
  宮本義孝、池内真志、野口洋文、林衆治
- Organizer
  第44回日本臓器保存生物医学会学術集会, 大阪
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] The long-term cryopreservation of various cell lines at -80.DEG.C.2016
- Author(s)
  MIYAMOTO Yoshitaka, IKEUCHI Masashi, NOGUCHI Hirofumi, HAYASHI Shuji
- Organizer
  第43回日本低温医学会総会
- Place of Presentation
  国立スポーツ科学センター, 東京
- Year and Date
  2016-10-17
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] コンビナトリアル・セルクラスターによる評価系の構築と技術評価－例として、磁性ナノ粒子による毒性評価－2016
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第15回日本再生医療学会総会
- Place of Presentation
  大阪国際会議場, 大阪
- Year and Date
  2016-03-17
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] ヒト脂肪由来幹細胞からマイクロティッシュの大量作製2016
- Author(s)
  宮本義孝、池内真志、野口洋文、八木透、生田幸士、林衆治
- Organizer
  第52回日本移植学会総会
- Place of Presentation
  グランドプリンスホテル新高輪, 東京
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] -80℃条件下における細胞株の長期凍結保存2016
- Author(s)
  宮本義孝、池内真志、野口洋文、生田幸士、林衆治
- Organizer
  第43回日本臓器保存生物医学会
- Place of Presentation
  東京薬科大学, 東京
- Year and Date
  2016-11-26
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] 3次元培養によるヒト脂肪由来幹細胞の脂肪への分化とマイクロティッシュの作製2016
- Author(s)
  宮本義孝、池内真志、野口洋文、八木透、生田幸士、林衆治
- Organizer
  第68回日本生物工学会大会
- Place of Presentation
  富山国際会議場, 富山
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] 培養デバイスTASCLによる初代肝細胞スフェロイド培養、および均一・大量生産系の確立2015
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第54回日本生体医工学会大会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Year and Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] コンビナトリアル・セルクラスターによる評価システムの構築－肝細胞クラスターによる磁性ナノ粒子の毒性評価－2015
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第42回日本臓器保存生物医学会学術集会
- Place of Presentation
  いわて県民情報交流センター, 盛岡
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] TASCLを用いた初代分離・培養細胞組織体の創製2015
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  シンポジウム：細胞アッセイ技術の現状と将来 (細胞アッセイ研究会)
- Place of Presentation
  東京大学生産技術研究所コンベンションホール, 東京
- Year and Date
  2015-01-13
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] 培養デバイスTASCLによる初代肝細胞スフェロイド培養、および均一・大量生産系の確立2015
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第54回日本生体医工学会大会
- Place of Presentation
  名古屋国際会議場, 名古屋
- Year and Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] 培養デバイスTASCLを用いた肝細胞組織体の創製2015
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第22 回ＨＡＢ研究機構学術年会
- Place of Presentation
  昭和大学, 東京
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-15H03039
[Presentation] 培養デバイスTASCLを用いた肝細胞組織体の創製2015
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第22回ＨＡＢ研究機構学術年会
- Place of Presentation
  昭和大学, 東京
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] iPS細胞作製技術を応用した膵幹細胞の人工的作成2014
- Author(s)
  野口洋文、齊藤一誠、片岡仁美、渡部昌実、野口寧文、西郷健一、長谷川正行、丸山通広、大月和宣、青山博道、松本育子、浅野武秀、圷尚武
- Organizer
  第41回日本膵・膵島移植研究会
- Place of Presentation
  愛知
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 3次元微細加工技術を利用した培養デバイスTASCLによる脂肪由来幹細胞の機能評価2013
- Author(s)
  宮本義孝, 池内真志, 野口洋文, 生田幸士, 林衆治
- Organizer
  第40回日本臓器保存生物医学会学術集会
- Place of Presentation
  東京医科大学
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] 膵島移植の現況と展望2012
- Author(s)
  野口洋文
- Organizer
  第11回再生医療学会総会
- Place of Presentation
  神奈川(招待講演)
- Year and Date
  2012-06-13
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 膵島移植と再生医療2012
- Author(s)
  野口洋文
- Organizer
  第39回日本臓器保存生物医学会
- Place of Presentation
  福島(招待講演)
- Year and Date
  2012-11-17
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 膵島移植・再生療法の現状と展望2012
- Author(s)
  野口洋文
- Organizer
  第12回日本先進糖尿病治療研究会
- Place of Presentation
  岡山(招待講演)
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 膵島移植の現況と展望2012
- Author(s)
  野口洋文
- Organizer
  平成24年度愛媛外科会総会
- Place of Presentation
  愛媛(招待講演)
- Year and Date
  2012-08-04
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 膵島移植と膵島再生療法について2012
- Author(s)
  野口洋文
- Organizer
  第5回AWA DM.com
- Place of Presentation
  徳島(招待講演)
- Year and Date
  2012-09-08
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 膵島移植の現況2012
- Author(s)
  野口洋文
- Organizer
  第8回信州難治性肝疾患治療研究会
- Place of Presentation
  長野(招待講演)
- Year and Date
  2012-09-28
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 膵島移植と再生医療2012
- Author(s)
  野口洋文
- Organizer
  第11回全国ヤングDMカンファレンス
- Place of Presentation
  大阪(招待講演)
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-24390316
[Presentation] 新規培養デバイスＴＡＳＣＬを用いた肝細胞スフェロイドアレイ
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜, 横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-25560248
[Presentation] 培養デバイス‘TASCL’ による三次元肝細胞組織体の機能評価
- Author(s)
  宮本義孝、池内真志、野口洋文、鈴木聡、八木透、生田幸士、林衆治
- Organizer
  第41回日本臓器保存生物医学会学術集会
- Place of Presentation
  千里ライフサイエンスセンター, 大阪
- Year and Date
  2014-11-28 – 2014-11-29
- Data Source
  KAKENHI-PROJECT-25560248

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NOGUCHI HIROFUMI 野口 洋文

NOGUCHI Hirofumi 野口 洋文

野口 洋文 ノグチ ヒロフミ

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Induction of human pancreatic stem cells by novel transcription factors without Yamanaka factorsPrincipal Investigator

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Induction of tissue-specific stem cells by novel transcription factors and/or small-molecule compoundsPrincipal Investigator

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Differentiatio of human stem cells into pancreatic islets using porcine body as in vivo bioreactorPrincipal Investigator

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NOGUCHI HIROFUMI 野口洋文

NOGUCHI Hirofumi 野口洋文

野口洋文ノグチヒロフミ