Konishi Akimitsu 小西昭充

… Alternative Names

KONISHI Akimitsu 小西昭充

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Researcher Number	50381877
Other IDs	https://orcid.org/0000-0002-3291-0821
Affiliation (Current)	2025: 獨協医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2025: 群馬大学, 大学院医学系研究科, 講師 2021 – 2023: 群馬大学, 大学院医学系研究科, 講師 2016 – 2019: 群馬大学, 大学院医学系研究科, 講師 2013 – 2015: 群馬大学, 医学(系)研究科(研究院), 講師 2014: 東京医科歯科大学, 難治疾患研究所, 講師 2011 – 2012: 東京医科歯科大学, 難治疾患研究所, 講師 2010: 東京医科歯科大学, 難治疾患研究所, 特任助教
Review Section/Research Field	Principal Investigator Cell biology / Basic Section 48040:Medical biochemistry-related / Basic Section 49010:Pathological biochemistry-related / Pathological medical chemistry / Biological Sciences Except Principal Investigator Functional biochemistry / Pathological medical chemistry
Keywords	Principal Investigator 細胞周期 / テロメア / DNA損傷応答 / 染色体末端融合 / DNA損傷反応 / 染色体不安定化 / DNA損傷 / 癌抑制 / ケミカルスクリーニング / 分子生物学 … More / DNA損傷チェックポイント / 酸化ストレス / メタボローム / エネルギー代謝 / アミノ酸代謝 / 活性酸素 / 分岐鎖アミノ酸 / 細胞老化 / 遺伝性乳ガン / ユビキチン化 / ゲノム不安定化 / 遺伝性乳癌 / 乳癌 / クロマチン / 細胞癌化 / DNA修復 … More Except Principal Investigator Atg5 / 癌 / オートファジー / 血液疾患 / Ulk1 / 細胞リモデリング / オートファジー病 / 低分子化合物 / alternative macroautophagy / 発癌 / 貧血 / ストレス / 生体分子 / シグナル伝達 / 遺伝学 / Atg5非依存的オートファジー / 発生 / 神経変性疾患 / がん / Atg5非依存性 Less

分岐鎖アミノ酸代謝による細胞・個体老化の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  小西昭充
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Gunma University
Elucidation of a novel cellular senescence mechanism modulated by branched-chain amino acid metabolism.Principal Investigator
- Principal Investigator
  
  Konishi Akimitsu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Gunma University
Understanding mechanism of genome instability in hereditary breast cancer induced by telomere dysfunctionPrincipal Investigator
- Principal Investigator
  
  Konishi Akimitsu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Gunma University
Defining the molecular mechanism of the cell cycle-specific regulation of chromosome end fusion at dysfunctional telomeresPrincipal Investigator
- Principal Investigator
  
  Konishi Akimitsu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Gunma University
DNA損傷チェックポイント回復機構の解析:細胞は如何に細胞周期を再開させるのか?Principal Investigator
- Principal Investigator
  
  小西昭充
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo Medical and Dental University
Studies of alternative macroautophagy and its application for "Autophagic Diseases"
- Principal Investigator
  
  SHIMIZU Shigeomi
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Tokyo Medical and Dental University
新しく発見したオートファジーを基盤とした細胞内浄化システムの包括的理解
- Principal Investigator
  
  清水重臣
- Project Period (FY)
  2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tokyo Medical and Dental University
Defining the molecular mechanism of checkpoint recovery from DNA damage.Principal Investigator
- Principal Investigator
  
  KONISHI Akimitsu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  Tokyo Medical and Dental University

All 2024 2023 2022 2021 2019 2018 2017 2016 2015 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] 分岐鎖アミノ酸代謝の変調と老化・加齢性疾患2024
- Author(s)
  大日方英, 小西昭充
- Journal Title
  
  基礎老化研究
  
  Volume: 48(1) Pages: 3-8
- Data Source
  KAKENHI-PROJECT-21K06852
[Journal Article] ミトコンドリアを経由するアポトーシス2022
- Author(s)
  小西　昭充
- Journal Title
  
  医学のあゆみ
  
  Volume: 283 Pages: 317-321
- Data Source
  KAKENHI-PROJECT-21K06852
[Journal Article] Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level2019
- Author(s)
  Tanaka Yuji、Konishi Akimitsu、Obinata Hideru、Tsuneoka Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 18694-18694
- DOI
  10.1038/s41598-019-55075-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07798, KAKENHI-PROJECT-17K08649
[Journal Article] Dram1 regulates DNA damage-induced alternative autophagy2018
- Author(s)
  Nagata M, Arakawa S, Yamaguchi H, Torii S, Endo H, Tsujioka M, Honda S, Nishida Y, Konishi A, Shimizu S
- Journal Title
  
  Cell Stress
  
  Volume: 2 Issue: 3 Pages: 55-65
- DOI
  10.15698/cst2018.03.127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08649, KAKENHI-PLANNED-17H06414, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230, KAKENHI-PROJECT-17K15448, KAKENHI-ORGANIZER-17H06413, KAKENHI-PROJECT-17H01533
[Journal Article] Protein purification and cloning of diacylglycerol lipase from rat brain.2016
- Author(s)
  Aso C, Araki M, Ohshima N, Tatei K, Hirano T, Obinata H, Kishi M, Kishimoto K, Konishi A, Goto F, Sugimoto H, Izumi T.
- Journal Title
  
  J. Biochem.
  
  Volume: 159 Issue: 6 Pages: 585-597
- DOI
  10.1093/jb/mvw002
- NAID
  40020869378
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390069, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-15K08284
[Journal Article] TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends.2016
- Author(s)
  Konishi A, Izumi T, Shimizu S
- Journal Title
  
  J Biol Chem.
  
  Volume: 291(39) Issue: 39 Pages: 20798-810
- DOI
  10.1074/jbc.m116.719021
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-16K15230
[Journal Article] Autophagy controls centrosome number by degrading Cep63.2016
- Author(s)
  Watanabe Y, Honda S, Konishi A, Satoko Arakawa S, Murohashi M, Yamaguchi H, Torii S, Tanabe M, Tanaka S, Warabi E, Shimizu S.
- Journal Title
  
  Nature Communications
  
  Volume: 7 Issue: 1 Pages: 13508-13508
- DOI
  10.1038/ncomms13508
- NAID
  120007129257
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01484, KAKENHI-PUBLICLY-15H01554, KAKENHI-PLANNED-26110005, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-15H04926, KAKENHI-PROJECT-25440080, KAKENHI-PROJECT-26430051, KAKENHI-PROJECT-26460485, KAKENHI-PROJECT-15K15491, KAKENHI-PROJECT-15K19004, KAKENHI-PROJECT-15K08420, KAKENHI-PROJECT-16K15230
[Journal Article] Enzymatic characterization of recombinant rat DDHD2: a soluble diacylglycerol lipase.2016
- Author(s)
  Araki M, Ohshima N, Aso C, Konishi A, Obinata H, Tatei K, Izumi T.
- Journal Title
  
  J. Biochem.
  
  Volume: 160 Issue: 5 Pages: 269-279
- DOI
  10.1093/jb/mvw034
- NAID
  40021012775
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390069, KAKENHI-PROJECT-25440080
[Journal Article] Involvement of beclin 1 in engulfment of apoptotic cells2012
- Author(s)
  Konishi, A., Arakawa, S., Yue, Z., and Shimizu, S
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 13919-13929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570180
[Journal Article] Involvement of Beclin 1 in the engulfment of apoptotic cells2012
- Author(s)
  Konishi A, Arakawa S, Yue Z, Shimizu S
- Journal Title
  
  J.Biol.Chem.
  
  Volume: (epub) Issue: 17 Pages: 13919-13929
- DOI
  10.1074/jbc.m112.348375
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019011, KAKENHI-PUBLICLY-22020009, KAKENHI-PUBLICLY-22121505, KAKENHI-PROJECT-22229002, KAKENHI-PROJECT-22570180, KAKENHI-PROJECT-22770054, KAKENHI-PROJECT-23657084, KAKENHI-PROJECT-24659178, KAKENHI-PUBLICLY-24121708
[Journal Article] Involvement of JNK in the regulation of autophagic cell death.2010
- Author(s)
  Shimizu S, Konishi A, Nishida Y, Mizuta T, Nishina H, Yamamoto A, Tsujimoto Y
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22019011
[Journal Article] Involvement of JNK in the regulation of autophagic cell death.2010
- Author(s)
  Shimizu S, Konishi A, Nishida Y, Mizuta T, Nishina H, Yamamoto A, Tsujimoto Y
- Journal Title
  
  Oncogene
  
  Volume: 29 Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570180
[Journal Article] Involvement of JNK in the regulation of autophagic cell death2010
- Author(s)
  Shimizu, S., Konishi, A., Nishida, Y., Mizuta, T., Nishina, H., Yamamoto, A., and Tsujimoto, Y
- Journal Title
  
  Oncogene 29
  
  Pages: 2070-2082
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] テロメア短縮系を用いた効率的な複製老化系の樹立および分岐鎖アミノ酸代謝の細胞老化における役割の解析2023
- Author(s)
  入江和樹, 荒牧佑磨, 土田愛子, 大日方英, 和泉孝志, 南嶋洋司, 小西昭充
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 代謝物解析から迫る細胞・個体老化~分岐鎖アミノ酸代謝の変調を中心に~2023
- Author(s)
  大日方英, 荒牧佑磨, 土田愛子, 入江和樹, 南嶋洋司, 小西昭充
- Organizer
  第46回日本基礎老化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 細胞老化過程における分岐鎖アミノ酸代謝の変調2023
- Author(s)
  大日方英, 荒牧佑磨, 入江和樹, 南嶋洋司, 小西昭充
- Organizer
  第71回質量分析総合討論会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調と細胞・個体老化2023
- Author(s)
  小西昭充
- Organizer
  第96回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調と細胞・個体老化2022
- Author(s)
  小西　昭充
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調と細胞・個体老化2022
- Author(s)
  小西　昭充
- Organizer
  第８回がんと代謝研究会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] テロメア短縮による細胞老化の過程で変化する細胞内タンパク質の網羅的解析2022
- Author(s)
  土田愛子, 入江和樹, 荒牧佑磨, 南嶋洋司, 小西昭充
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] Filamin B regulates the endocytosis of endothelial sphingosine 1-phosphate receptor 12022
- Author(s)
  Zhao Xian, Keisuke Kyozuka, Akimitsu Konishi, Yoji A. Minamishima, Hideru Obinata
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調と細胞・個体老化2022
- Author(s)
  小西　昭充
- Organizer
  第９回DNA損傷応答ワークショップ
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] Development of rapid and efficient induction system for replicative senescence by mimicking telomere shortening2021
- Author(s)
  Yuma Aramaki, Kazuki Irie, Aiko Tsuchida, Takashi Izumi, Yoji A. Minamishima, Akimitsu Konishi
- Organizer
  International Cell Senescence Association Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調による細胞老化制御機構2021
- Author(s)
  小西昭充、荒牧佑磨、大日方英、本田真也、和泉孝志、清水重臣、南嶋洋司
- Organizer
  日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 分岐鎖アミノ酸代謝の変調による細胞老化制御機構2021
- Author(s)
  荒牧佑磨、大日方英、本田真也、和泉孝志、清水重臣、南嶋洋司、小西昭充
- Organizer
  日本生化学会関東支部例会
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] Modulation of Cellular Senescence by Branched- Chain Amino Acid Metabolism2021
- Author(s)
  Yuma Aramaki, Hideru Obinata, Shinya Honda, Takashi Izumi, Shigeomi Shimizu, Yoji A. Minamishima, Akimitsu Konishi
- Organizer
  International Cell Senescence Association Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06852
[Presentation] 早期細胞老化誘導時に起こる細胞内代謝変化への理解2019
- Author(s)
  小西昭充
- Organizer
  第８回DNA損傷応答ワークショップ
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] BRCA1 complex regulates cell cycle-dependent DNA damage response at telomeres to maintain chromosome integrity2019
- Author(s)
  小西昭充、南嶋洋司
- Organizer
  第７８回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] 早期細胞老化におけるアミノ酸代謝の変調2019
- Author(s)
  荒牧佑磨、小西昭充、南嶋洋司
- Organizer
  第４２回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] メトホルミンはKDM2A依存的なrRNA転写抑制及び細胞増殖抑制を引き起こす2018
- Author(s)
  田中祐司、小西昭充、大日方英、南雲美奈代、和泉桃佳、岡本健吾、常岡誠
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] 骨芽細胞様細胞MC3T3-E1におけるアクチン細胞骨格再構成を介した炎症性脂質メディエーター誘導性の骨形成制御メカニズムの解析2018
- Author(s)
  鈴木啓、大嶋紀安、小西昭充、立井一明、佐藤精一、和泉孝志
- Organizer
  第４１回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] ゲノム損傷ストレスによって誘導されるオートファジー2018
- Author(s)
  小西昭充
- Organizer
  第７回DNA損傷応答ワークショップ
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] Autophagy controls centrosome number by degrading Cep632018
- Author(s)
  Yuichiro Watanabe, Akimitsu Konishi, Shinji Tanaka, Shigeomi Shimizu
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] ゲノム編集技術を用いた蛍光蛋白ラベル法による内在性p53蛋白動態の1細胞解析2017
- Author(s)
  荒牧佑磨、小西昭充、和泉孝志
- Organizer
  染色体ワークショップ
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] ゲノム編集技術を用いた蛍光蛋白ラベル法による内在性p53蛋白動態の1細胞解析2017
- Author(s)
  荒牧佑磨、小西昭充、和泉孝志
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] TRF2はコアヒストンとの直接結合によりテロメアのループ構造を維持する2017
- Author(s)
  小西昭充、和泉孝志、清水重臣
- Organizer
  第34回染色体ワークショップ
- Place of Presentation
  松島
- Year and Date
  2017-01-12
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] ゲノム編集技術を用いた可視化による内在性p53蛋白ダイナミクスの一細胞解析2017
- Author(s)
  小西昭充
- Organizer
  DNA損傷応答ワークショップ
- Data Source
  KAKENHI-PROJECT-17K08649
[Presentation] Cell cycle-dependent regulation of DNA damage response at dysfunctional telomeres2016
- Author(s)
  Hiraku Suzuki, Anastasie Tshilela Kadiombo, Akimitsu Konishi, Takashi Izumi
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] テロメアにおける細胞周期依存的なDNA損傷反応・DNA修復の制御機構2016
- Author(s)
  小西　昭充
- Organizer
  第6回DNA損傷応答ワークショップ
- Place of Presentation
  浜松
- Year and Date
  2016-04-04
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Cell cycle-dependent regulation of non-homologous end joining at unprotected telomeres2016
- Author(s)
  Kadiombo Tshilela Anastasie, Akimitsu Konishi, Takashi Izumi
- Organizer
  第３３回染色体ワークショップ
- Place of Presentation
  松島一の坊（宮城県宮城郡松島町）
- Year and Date
  2016-01-12
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] オートファジーによるCep63の分解を介した中心体数の制御2016
- Author(s)
  本田真也, 渡辺雄一郎, 小西昭充, 室橋道子, 荒川聡子, 山口啓史, 清水重臣
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Cell Cycle-Dependent Regulation of DNA Damage Response and DNA Repair at Dysfunctional Telomeres2016
- Author(s)
  Akimitsu Konishi
- Organizer
  10th 3R Symposium
- Place of Presentation
  Matsue
- Year and Date
  2016-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] TRF2 interacts with core histones to stabilize chromosome ends2015
- Author(s)
  Akimitsu Konishi
- Organizer
  EMBO Workshop Telomeric Chromatin and telomere fragility
- Place of Presentation
  Singapore（シンガポール）
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Cell Cycle-Dependent Regulation of DNA Damage Response and DNA Repair at Dysfunctional Telomeres2015
- Author(s)
  Akimitsu Konishi
- Organizer
  Cold Spring Harbor Meeting Telomere & Telomerase
- Place of Presentation
  Cold Spring Harbor, NY （米国）
- Year and Date
  2015-04-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Cell cycle-dependent regulation of non-homologous end joining at unprotected telomeres2015
- Author(s)
  Kadiombo Tshilela Anastasie, Akimitsu Konishi, Takashi Izumi
- Organizer
  第３８回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Complete sequence of human telomere DNA by single-molecule real-time sequencing technique2015
- Author(s)
  Kaori Yauchi, Akimitsu Konishi, Takashi Izumi
- Organizer
  EMBO Workshop Telomeric Chromatin and telomere fragility
- Place of Presentation
  Singapore（シンガポール）
- Year and Date
  2015-12-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Wee1 によるDNA損傷チェックポイントの回復制御2013
- Author(s)
  小西昭充、和泉孝志、清水重臣
- Organizer
  第31回染色体ワークショップ
- Place of Presentation
  箱根
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Regulation of DNA damage checkpoint termination2013
- Author(s)
  Akimitsu Konishi, Takashi Izumi, Shigeomi Shimizu
- Organizer
  第３６回日本分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] テロメア結合蛋白TRF2のコアヒストンとの相互作用による染色体末端安定化機構2012
- Author(s)
  小西昭充、清水重臣、Titia de Lange
- Organizer
  染色体ワークショップ
- Place of Presentation
  仙台
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] DNA損傷チェックポイントの回復機構2012
- Author(s)
  Konishi A
- Organizer
  日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] テロメア結合蛋白TRF2 のコアヒストンとの相互作用による染色体末端安定化機構2012
- Author(s)
  小西昭充、清水重臣、Titia de Lange
- Organizer
  染色体ワークショップ
- Place of Presentation
  仙台
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] Checkpoint recovery from DNA damage2012
- Author(s)
  Konishi A
- Organizer
  日本癌学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] テロメア結合蛋白TRF2のコアヒストンとの相互作用による染色体末端安定化機構2012
- Author(s)
  小西昭充、清水重臣、Titia de Lange
- Organizer
  染色体ワークショップ
- Place of Presentation
  仙台
- Year and Date
  2012-01-25
- Data Source
  KAKENHI-PUBLICLY-22019011
[Presentation] Checkpoint recovery from DNA damage2012
- Author(s)
  Konishi A
- Organizer
  日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌（北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] DNA損傷チェックポイントの回復機構2012
- Author(s)
  Konishi A
- Organizer
  日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Invited
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO STABILIZE CHROMOSOME ENDS2011
- Author(s)
  小西昭充、清水重臣、Titia de Lange
- Organizer
  研究所ネットワーク国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO PROTECT CHROMOSOME ENDS2011
- Author(s)
  Konishi A, Shimizu S, de Lange T
- Organizer
  分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PUBLICLY-22019011
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO PROTECT CHROMOSOME ENDS2011
- Author(s)
  小西昭充、清水重臣、Titia de Lange
- Organizer
  研究所ネットワーク国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PUBLICLY-22019011
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO PROTECT CHROMOSOME ENDS2011
- Author(s)
  Konishi A, Shimizu S, de Lange T
- Organizer
  分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] TRF2BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO STABILIZE CHROMOSOME ENDS2011
- Author(s)
  Konishi A, Shimizu S, de Lange T
- Organizer
  分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO PROTECT CHROMOSOME ENDS2011
- Author(s)
  小西昭充、清水重臣、Titia de Lange
- Organizer
  研究所ネットワーク国際シンポジウム
- Place of Presentation
  東京
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] Checkpoint Recovery fromDNA damage2010
- Author(s)
  Konishi A
- Organizer
  MEXT Priority ResearchProject 国際シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] オートファジー因子Beclin1によるアポトーシス細胞除去の制御2010
- Author(s)
  小西昭充、荒川聡子、清水重臣
- Organizer
  日本Cell Death学会
- Place of Presentation
  名古屋
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] TRF2BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO STABILIZE CHROMOSOME ENDS2010
- Author(s)
  Konishi A, Shimizu S, de Lange T
- Organizer
  分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO STABILIZE CHROMOSOME ENDS2010
- Author(s)
  Konishi A, Shimizu S, de Lange T
- Organizer
  分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PUBLICLY-22019011
[Presentation] TRF2 BASIC DOMAIN INTERACTS WITH NUCLEOSOMAL HISTONES TO STABILIZE CHROMOSOME ENDS2010
- Author(s)
  Konishi A, Shimizu S, de Lange T
- Organizer
  分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22570180
[Presentation] 細胞はどのようにしてDNA損傷から回復するのか
- Author(s)
  小西昭充
- Organizer
  群馬大学ASRLDシンポジウム
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] テロメアにおける細胞周期依存的なDNA損傷反応・DNA修復の制御機構
- Author(s)
  小西昭充、和泉孝志、Titia de Lange
- Organizer
  染色体ワークショップ
- Place of Presentation
  広島
- Year and Date
  2014-12-15 – 2014-12-17
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] Cell Cycle-Dependent Regulation of DNA Damage Response and DNA Repair at Dysfunctional Telomeres.
- Author(s)
  Akimitsu Konishi, Takashi Izumi, Titia de Lange
- Organizer
  4D Nucleome
- Place of Presentation
  広島
- Year and Date
  2014-12-17 – 2014-12-20
- Data Source
  KAKENHI-PROJECT-25440080
[Presentation] テロメアでの細胞周期依存的なDNA損傷反応・DNA修復の制御機構
- Author(s)
  小西昭充、和泉孝志、Titia de Lange
- Organizer
  第３７回分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25440080

1. SHIMIZU Shigeomi (70271020)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. YOSHIDA Tatsushi (80315936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ARAKAWA Satoko (90415159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大日方英 (50332557)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. OHSHIMA Noriyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 岸本幸治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 和泉孝志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 立井一明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 田中祐司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Konishi Akimitsu 小西 昭充

KONISHI Akimitsu 小西 昭充

Research Projects

Research Products

Co-Researchers

分岐鎖アミノ酸代謝による細胞・個体老化の分子メカニズムの解明Principal Investigator

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Elucidation of a novel cellular senescence mechanism modulated by branched-chain amino acid metabolism.Principal Investigator

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Understanding mechanism of genome instability in hereditary breast cancer induced by telomere dysfunctionPrincipal Investigator

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Defining the molecular mechanism of the cell cycle-specific regulation of chromosome end fusion at dysfunctional telomeresPrincipal Investigator

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DNA損傷チェックポイント回復機構の解析:細胞は如何に細胞周期を再開させるのか?Principal Investigator

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Studies of alternative macroautophagy and its application for "Autophagic Diseases"

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新しく発見したオートファジーを基盤とした細胞内浄化システムの包括的理解

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Defining the molecular mechanism of checkpoint recovery from DNA damage.Principal Investigator

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[Journal Article] 分岐鎖アミノ酸代謝の変調と老化・加齢性疾患2024

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[Journal Article] ミトコンドリアを経由するアポトーシス2022

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[Journal Article] Metformin activates KDM2A to reduce rRNA transcription and cell proliferation by dual regulation of AMPK activity and intracellular succinate level2019

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DOI

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[Journal Article] Dram1 regulates DNA damage-induced alternative autophagy2018

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[Journal Article] Protein purification and cloning of diacylglycerol lipase from rat brain.2016

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NAID

Data Source

[Journal Article] TRF2 Protein Interacts with Core Histones to Stabilize Chromosome Ends.2016

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Konishi Akimitsu 小西昭充

KONISHI Akimitsu 小西昭充