OHASHI Naro 大橋温

… Alternative Names

Ohashi Naro 大橋温

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Researcher Number	50397387
Affiliation (Current)	2025: 浜松医科大学, 地域診療教育システム開発センター, 特任教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 浜松医科大学, 医学部附属病院, 特任准教授 2017 – 2019: 浜松医科大学, 医学部附属病院, 特任講師 2006: Hamamatsu University School of Medicine, Senior resident, 医学部, 医員 2006: 浜松医科大学, 医学部附属病院, 医員 2005: 浜松医科大学, 医学部, リサーチアシスタント
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 53040:Nephrology-related Except Principal Investigator Basic Section 58080:Gerontological nursing and community health nursing-related / Kidney internal medicine
Keywords	Principal Investigator 腎臓内レニン-アンジオテンシン系 / 腎臓障害 / コリン作動性抗炎症反応経路 / 高血圧 / 運動 / 慢性腎臓病 / 糸球体過剰濾過 / 糸球体濾過値 / in vivo imaging / 日内変動 … More / 糸球体濾過圧 / アンジオテンシノーゲン / PI3 kinase-Akt経路 / Smad / 転写 / シグナル伝達 / TGF-β / ユビキチンリガーゼ / Smurf2 … More Except Principal Investigator Smad / Ski / SnoN / α-Klotho / 低強度身体活動 / 慢性腎臓病 / 高齢 / 予後改善 / 腎臓リハビリテーション / 有害事象 / 身体機能 / 透析導入患者 / intracellular signaling / kidney fibrosis / TGF-p / ubiquitin / 細胞内信号伝達 / 腎硬化 / TGF-β / ユビキチン Less

高齢慢性腎臓病患者の虚弱性進行機序解明と新たな治療基盤の確立：透析導入期への着眼
- Principal Investigator
  
  平野裕真
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Hamamatsu University School of Medicine
高齢透析導入患者における早期有害事象発生のリスク因子の解明：新たな治療戦略の開発
- Principal Investigator
  
  山口智也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58080:Gerontological nursing and community health nursing-related
- Research Institution
  Hamamatsu University School of Medicine
Exercise improves renal injury by inhibiting renal RAS through cholinergic anti-inflammatory response pathwayPrincipal Investigator
- Principal Investigator
  
  Ohashi Naro
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Hamamatsu University School of Medicine
Angiotensinogen originating from liver by glomerular filtration pressure is involved in circadian rhythm of intrarenal renin-angiotensin system.Principal Investigator
- Principal Investigator
  
  Ohashi Naro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine
ユビキチンリガーゼSmurf2の転写調節メカニズムの解明Principal Investigator
- Principal Investigator
  
  大橋温
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine
Progression of kidney fibrosis and ubiquitin-proteasome degradation of inhibitory factors for Smad-TGF-p signaling
- Principal Investigator
  
  TATSUO Yamamoto
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Hamamatsu University School of Medicine

All 2025 2024 2020 2019 2005

All Journal Article Presentation

[Journal Article] Effect of rehabilitation on renal outcomes after acute kidney injury associated with cardiovascular disease: a retrospective analysis2024
- Author(s)
  Hirano Yuma、Fujikura Tomoyuki、Kono Kenichi、Yamaguchi Tomoya、Ohashi Naro、Yokoyama Yurina、Toda Masahiro、Yamauchi Katsuya、Yasuda Hideo
- Journal Title
  
  BMC Nephrology
  
  Volume: 25 Issue: 1 Pages: 222-222
- DOI
  10.1186/s12882-024-03666-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11190, KAKENHI-PROJECT-21K11285, KAKENHI-PROJECT-23K10286
[Journal Article] The Association Between the Perception of Exercise Benefits and Barriers and Exercise Self-Efficacy During the Induction Phase of Dialysis in Patients with End-Stage Kidney Disease: A Cross-Sectional Study2024
- Author(s)
  Hirano Yuma、Fujikura Tomoyuki、Yamaguchi Tomoya、Kato Akihiko、Kono Kenichi、Ohashi Naro、Yasuda Hideo、Yamauchi Katsuya
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 13 Issue: 21 Pages: 6332-6332
- DOI
  10.3390/jcm13216332
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11190, KAKENHI-PROJECT-21K11285, KAKENHI-PROJECT-23K10286
[Journal Article] The Urinary Angiotensinogen to Urinary Albumin Ratio Reflects Whether the Renin-angiotensin System in the Kidney Is Activated due to Filtration of Plasma Angiotensinogen through the Damaged Glomeruli or the Production of Angiotensinogen in the Proximal Tubules2020
- Author(s)
  Ohashi N, Aoki T, Matsuyama T, Ishigaki S, Isobe S, Katahashi N, Sato T, Fujikura T, Kato A, Yasuda H.
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 3 Pages: 357-364
- DOI
  10.2169/internalmedicine.3624-19
- NAID
  130007793871
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-02-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09693
[Journal Article] Increased heart rate is associated with intrarenal renin-angiotensin system activation in chronic kidney disease patients.2019
- Author(s)
  Ohashi N, Isobe S, Ishigaki S, Aoki T, Matsuyama T, Sato T, Fujikura T, Kato A, Yasuda H.
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 23 Issue: 9 Pages: 1109-1118
- DOI
  10.1007/s10157-019-01746-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09693
[Journal Article] The Intrarenal Renin-angiotensin System Is Activated Immediately after Kidney Donation in Kidney Transplant Donors2019
- Author(s)
  Ohashi N, Isobe S, Matsuyama T, Ishigaki S, Suzuki T, Tsuji T, Otsuka A, Kato A, Miyake H, Yasuda H.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 5 Pages: 643-648
- DOI
  10.2169/internalmedicine.1756-18
- NAID
  130007605865
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09693
[Journal Article] Salt Loading Aggravates the Relationship between Melatonin and Proteinuria in Patients with Chronic Kidney Disease2019
- Author(s)
  Ohashi N, Ishigaki S, Isobe S, Matsuyama T, Sato T, Fujikura T, Tsuji T, Kato A, Yasuda H.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 11 Pages: 1557-1564
- DOI
  10.2169/internalmedicine.1929-18
- NAID
  130007658135
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-06-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09693
[Journal Article] Transcriptional induction of Smurf2 ubiquitin ligase by TGF-beta.2005
- Author(s)
  Naro Ohashi
- Journal Title
  
  FEBS Lett. 579・12
  
  Pages: 2557-2563
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590824
[Journal Article] Transcriptional induction of Smurf2 ubiquitin ligase by PGF-beta.2005
- Author(s)
  Ohashi N, Yamamoto T, Uchida C, Togawa A, Fukasawa H, Fujigaki Y, Suzuki S, Kitagawa K, Hattori T, Oda T, Hayashi H, Hishida A, Kitagawa M.
- Journal Title
  
  FEES Lett. 579・2
  
  Pages: 2557-2563
- Data Source
  KAKENHI-PROJECT-17590824
[Journal Article] Transcriptional induction of Smurf2 ubiquitin ligase by TGF-β2005
- Author(s)
  Naro Ohashi
- Journal Title
  
  FEBS Letters 579
  
  Pages: 2557-2563
- Data Source
  KAKENHI-PROJECT-17790550
[Journal Article] Transcriptional induction o : Smurf2 ubiquitin ligase by TGF-beta.2005
- Author(s)
  Naro Ohashi, et al.
- Journal Title
  
  FEBS Lett. 579-12
  
  Pages: 2557-2563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590824
[Presentation] 透析クリニック連携による透析導入患者の身体機能支援体制構築 ― 理学療法士のフィードバックを用いた評価とフォローアップ ―2025
- Author(s)
  山口智也 , 矢部広樹 , 平野裕真 , 藤倉知行 , 大橋温 , 山内克哉 , 加藤明彦
- Organizer
  第15回透析運動療法研究会
- Data Source
  KAKENHI-PROJECT-23K10286
[Presentation] 血液透析導入期におけるフレイルと非計画導入との関連 -単施設横断研究-2025
- Author(s)
  山口智也 , 矢部広樹 , 平野裕真 , 藤倉知行 , 大村朋矢 , 大橋温 , 安田日出夫 , 山内克哉 , 加藤明彦
- Organizer
  第15回日本腎臓リハビリテーション学会学術集会
- Data Source
  KAKENHI-PROJECT-23K10286
[Presentation] Increased heart rate reflects intrarenal renin-angiotensin system activation in chronic kidney disease patients but not in subjects without chronic kidney disease.2019
- Author(s)
  Ohashi N, Isobe S, Ishigaki S, Aoki T, Matsuyama T, Sato T, Fujikura T, Kato A,
- Organizer
  Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09693
[Presentation] CKDにおける尿中アンジオテンシノーゲン排泄量と腎機能低下の関係2019
- Author(s)
  石垣さやか, 大橋温, 青木太郎, 田代傑, 後藤大樹, 松山貴司, 永田総一郎, 佐藤太一, 内藤善隆, 藤倉知行, 加藤明彦, 安田日出夫
- Organizer
  日本腎臓学会
- Data Source
  KAKENHI-PROJECT-17K09693
[Presentation] Chronotherapy of renin-angiotensin system (RAS) inhibitor ameliorates renal damage via suppression of intrarenal RAS activity.2019
- Author(s)
  Aoki T, Ohashi N, Isobe S, Ishigaki S, Matsuyama T, Fujikura T, Kato A, Yasuda H.
- Organizer
  Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09693

1. 加藤明彦 (60324357)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. 安田日出夫 (60432209)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 山口智也 (50962560)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. 平野裕真 (70834513)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 山内克哉 (40377750)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
6. 藤倉知行 (00444349)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. TATSUO Yamamoto (30200819)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. KITAGAWA Masatoshi (50294971)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. FUKASAWA Hirotaka (60397370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 矢部広樹 (40780664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 河野健一 (10638480)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 永房鉄之 (20397376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHASHI Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

OHASHI Naro 大橋 温

Ohashi Naro 大橋 温

Research Projects

Research Products

Co-Researchers

高齢慢性腎臓病患者の虚弱性進行機序解明と新たな治療基盤の確立：透析導入期への着眼

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

高齢透析導入患者における早期有害事象発生のリスク因子の解明：新たな治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exercise improves renal injury by inhibiting renal RAS through cholinergic anti-inflammatory response pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Angiotensinogen originating from liver by glomerular filtration pressure is involved in circadian rhythm of intrarenal renin-angiotensin system.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ユビキチンリガーゼSmurf2の転写調節メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Progression of kidney fibrosis and ubiquitin-proteasome degradation of inhibitory factors for Smad-TGF-p signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Effect of rehabilitation on renal outcomes after acute kidney injury associated with cardiovascular disease: a retrospective analysis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Association Between the Perception of Exercise Benefits and Barriers and Exercise Self-Efficacy During the Induction Phase of Dialysis in Patients with End-Stage Kidney Disease: A Cross-Sectional Study2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Urinary Angiotensinogen to Urinary Albumin Ratio Reflects Whether the Renin-angiotensin System in the Kidney Is Activated due to Filtration of Plasma Angiotensinogen through the Damaged Glomeruli or the Production of Angiotensinogen in the Proximal Tubules2020

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Increased heart rate is associated with intrarenal renin-angiotensin system activation in chronic kidney disease patients.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Intrarenal Renin-angiotensin System Is Activated Immediately after Kidney Donation in Kidney Transplant Donors2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Salt Loading Aggravates the Relationship between Melatonin and Proteinuria in Patients with Chronic Kidney Disease2019

Author(s)

Journal Title

DOI

NAID

ISSN

OHASHI Naro 大橋温

Ohashi Naro 大橋温

[Presentation] 透析クリニック連携による透析導入患者の身体機能支援体制構築 ― 理学療法士のフィードバックを用いた評価とフォローアップ ―2025