Hattori Fumiyuki 服部文幸

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HATTORI Fumiyuki 服部文幸

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Researcher Number	50398624
Other IDs	https://orcid.org/0000-0002-8936-9941
Affiliation (Current)	2025: 関西医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 関西医科大学, 医学部, 教授 2012 – 2013: 慶應義塾大学, 医学部, 講師(非常勤) 2011: 慶應義塾大学, 医学部, 講師 2010: Keio University, 医学部, 研究員 2005 – 2010: 慶應義塾大学, 医学部, 共同研究員
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 53020:Cardiology-related / Basic Section 48030:Pharmacology-related Except Principal Investigator Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 53030:Respiratory medicine-related / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Circulatory organs internal medicine
Keywords	Principal Investigator 心筋細胞 / 再生医療 / 多能性幹細胞 / 心臓再生 / 移植 / 霊長類 / 心不全 / 成熟 / 心筋 / ヒトiPS細胞 … More / 心筋梗塞モデル / 同種移植 / ES細胞 / 再生医学 / gene expression / growth / characterization / differentiation / embryonic stem cell / Cardiomyocytes / Common Marmoset / 胚性幹細胞 / 細胞シート / マーモセット … More Except Principal Investigator 心筋細胞 / Therapeutic time window / MRONJ / ドライマウス / 唾液線幹細胞 / 薬剤スクリーニング / 疾患特異的iPS細胞 / 嚢胞性線維症 / iPS / 重症化 / ２型アンギオテンシン変換酵素 / アンギオテンシンⅡ / 新型コロナウイルス感染症 / SARS-CoV-2 / SARS-COV-2 / COVID-19 / Cell Transplantation / Noggin / Development / differentiation / Cardiomyocyte / Regeneratie Medicine / common marmosset / human embryonic stem cell / 心筋梗塞 / イオンチャネル / NKX2.5 / 転写因子 / 多分化能 / 奇形腫 / 胚性幹細胞 / 細胞移植 / ノギン / 発生学 / 分化誘導 / 再生医学 / コモンマーモセット / ヒト胚性幹細胞 Less

日本人嚢胞性線維症患者由来iPS細胞を用いた汎粘膜改善薬の探索
- Principal Investigator
  
  山下裕美
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kansai Medical University
ヒトiPS細胞由来唾液腺幹細胞を用いた再生治療におけるTherapeutic time windowの同定
- Principal Investigator
  
  澤田俊輔
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Kansai Medical University
TGFβ1を用いたヒトiPS細胞由来心筋細胞による心臓再生医療の高度化Principal Investigator
- Principal Investigator
  
  服部文幸
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kansai Medical University
COVID-19における急激な病態悪化メカニズムの解明および予防ターゲットの提示
- Principal Investigator
  
  伊藤明日香
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Kansai Medical University
Elucidation of embryological maturation switch of cardiomyocytes and application to human iPS cell-derived cardiomyocytesPrincipal Investigator
- Principal Investigator
  
  HATTORI Fumiyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kansai Medical University
Validation of therapeutic efficacy of allogenic transplantation therapy using pluripotent stem stem cell-derived cardiomyocytes for myocardial infarction in non-human primate: common marmoset.Principal Investigator
- Principal Investigator
  
  HATTORI Fumiyuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Keio University
Fabrication and Transplantation of Common Marmoset ES cells-derived cardiomyocyte-sheetsPrincipal Investigator
- Principal Investigator
  
  HATTORI Fumiyuki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Keio University
Development of regeneration, purification, and transplantation of cardiomyocytes from mouse and common marmoset ES cells
- Principal Investigator
  
  FUKUDA Keiichi
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University

All 2022 2013 2012 2010 2008 2007 2005

All Journal Article Presentation Patent

[Journal Article] Possible internal viral shedding and interferon production after clinical recovery from COVID-19: Case report2022
- Author(s)
  Ito Asuka、Okada Takayuki、Minato Naoki、Hattori Fumiyuki
- Journal Title
  
  Frontiers in Medicine
  
  Volume: 9 Pages: 01-06
- DOI
  10.3389/fmed.2022.959196
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10407
[Journal Article] Distinct Metabolic Flow Enable Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes.2013
- Author(s)
  Tohyama S, Hattori F, Sano M, et al.
- Journal Title
  
  Cell Stem Cell
  
  Volume: 12 Issue: 1 Pages: 127-37
- DOI
  10.1016/j.stem.2012.09.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J05269, KAKENHI-PROJECT-11J30002, KAKENHI-PROJECT-22689027, KAKENHI-PROJECT-23390072, KAKENHI-PROJECT-24651265, KAKENHI-PROJECT-25461117, KAKENHI-PUBLICLY-24117716
[Journal Article] Distinct iPS Cells shows different Cardiac Differentiation Efficiency.2013
- Author(s)
  Ohno Y, Yuasa S, Seki T, Fukuda K., et al.
- Journal Title
  
  Stem Cells International
  
  Volume: 2013 Pages: 659739-659739
- DOI
  10.1155/2013/659739
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J30002, KAKENHI-PROJECT-13J30005, KAKENHI-PROJECT-23390072, KAKENHI-PUBLICLY-24117716, KAKENHI-PROJECT-25461117
[Journal Article] Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium.2010
- Author(s)
  服部文幸、福田恵一
- Journal Title
  
  Experimental Molecular Medicine
  
  Volume: 42 Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790236
[Journal Article] Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium.2010
- Author(s)
  Hattori F, Fukuda K.
- Journal Title
  
  Exp Mol Med. 42(3)
  
  Pages: 155-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790236
[Journal Article] Common marmoset embryonic stem cell can differentiate into Cardiomyocytes.2008
- Author(s)
  Chen H, Hattori F, Murata M, Fukuda K., et. al.
- Journal Title
  
  Biophys Biochem Res Comm. 369
  
  Pages: 801-806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209029
[Journal Article] Common marmoset embryonic stem cell can differentiate into Cardiomyocytes.2008
- Author(s)
  Hao Chen, Fumiyuki Hattori, Mitsushige Murata, Weizhen Li, Shinsuke Yuasa, Takeshi Onizuka, Kenichiro Shimoji, Yohei Ohno, Erika Sasaki, Kensuke Kimura, Daihiko Hakuno, Motoaki Sano, Shinji Makino, Satoshi Ogawa, Keiichi Fukuda.
- Journal Title
  
  Biophys Biochem Res Comm. 369
  
  Pages: 801-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209029
[Journal Article] Common marmoset embryonic stem cell can differentiate into cardiomyocytes.2008
- Author(s)
  Chen H, Hattori F, Murata M, Li W, Yuasa S, Onizuka T, Shimoji K, Ohno Y, Sasaki E, Kimura K, Hakuno D, Sano M, Makino S, Ogawa S, Fukuda K.
- Journal Title
  
  Biochem Biophys Res Commun. 369(3)
  
  Pages: 801-806
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790236
[Journal Article] Common marmoset embryonic stem cell can differentiate into cardiomyocytes2008
- Author(s)
  Chen H, Hattori F, Murata M, Li W, Yuasa S, Onizuka T, Shimoji K, Ohno Y, Sasaki E, Kimura K, Hakuno D, Sano M, Makino S, Ogawa S, Fukuda K.
- Journal Title
  
  Biochemical and Biophysical Research Communications 369
  
  Pages: 801-801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790236
[Journal Article] Common marmoset embryonic stem cell can differentiate into Cardio myocytes.2008
- Author(s)
  Chen H, Hattori F, Murata M, Fukuda K, et al.
- Journal Title
  
  Biophys Biochem Res Comm. 369
  
  Pages: 801-806
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17209029
[Journal Article] Transient and strong inhibition of BMP signals by Noggin induces cardiomyocyte differentiation in murine embryonic stem cells.2005
- Author(s)
  Shinsuke Yuasa, Yuji Itabashi, Uichi Koshimizu, Tomofumi Tanaka, Keijiro Sugimura, Masayoshi Kinoshita, Fumiyuki Hattori, Shin-ichi Fukami, Takuya Shimazaki, Satoshi Ogawa, Hideyuki Okano, Keiichi Fukuda.
- Journal Title
  
  Nature Biotechnology 23
  
  Pages: 607-611
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17209029
[Patent] 心筋細胞の細胞塊作成方法および心筋細胞塊の用途2007
- Inventor(s)
  服部文幸、福田恵一
- Industrial Property Rights Holder
  アスビオファーマ、学校法人慶應義塾
- Industrial Property Number
  2007-200246
- Filing Date
  2007-07-31
- Data Source
  KAKENHI-PROJECT-17209029
[Patent] 心筋細胞の細胞塊作成方法および心筋細胞塊の用途2007
- Inventor(s)
  服部文幸, 福田恵一
- Industrial Property Rights Holder
  アスビオフアーマ, 学校法人慶應義塾
- Industrial Property Number
  2007-200246
- Filing Date
  2007-07-31
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209029
[Presentation] iPS細胞を活用した心臓再生医療と創薬応用に向けた現状と今後2013
- Author(s)
  服部文幸
- Organizer
  日本学術会議　薬学委員会　生物系薬学分科会シンポジウム
- Place of Presentation
  日本学術会議講堂
- Invited
- Data Source
  KAKENHI-PROJECT-23390072
[Presentation] Progress of a heart cell-therapy model system in Common Marmoset using Embryonic stem cells2012
- Author(s)
  服部文幸,山下裕美
- Organizer
  日本マーモセット研究会
- Place of Presentation
  東京医科歯科大学鈴木章夫記念講堂
- Data Source
  KAKENHI-PROJECT-23390072
[Presentation] 非遺伝子改変心筋細胞精製方法および移植方法2010
- Author(s)
  服部文幸
- Organizer
  日本再生医学会
- Place of Presentation
  広島国際会議場
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-20790236
[Presentation] 心臓再生医療の実現を目指した、心筋細胞精製および効率的移植方法の開発2010
- Author(s)
  服部文幸
- Organizer
  第55回未来医療センターセミナー
- Place of Presentation
  大阪大学
- Year and Date
  2010-07-20
- Data Source
  KAKENHI-PROJECT-20790236
[Presentation] Characterization of Common M armoset Monkey ES Cell-Derived Cardiomyocytes and Formation of Cardiac Cell-Sheet.2008
- Author(s)
  Hao C, Hattori F, Onizuka T, Yuasa S, Shimoji K, Ohno Y, Hara M, Fukuda K.
- Organizer
  第72回日本循環器学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-03-30
- Data Source
  KAKENHI-PROJECT-17209029
[Presentation] Characterization of Common Marmoset Monkey ES Cell-Derived Cardiomyocytes and Formation of Cardiac Cell-Sheet.2008
- Author(s)
  Hao C, Hattori F, Onizaka. T, Yuasa S, Shimoji K, Ohno Y, Hara M, Fukuda K.
- Organizer
  第72回日本循環器学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-03-30
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17209029
[Presentation] Cardiomyocyte Differentiation from Embryonic Stem Cells2008
- Author(s)
  Yuasa S, Shimoji K, Onizuka T, Ohno Y, Hattori F, Hara M, Hao C, Ogawa S, Fukuda K.
- Organizer
  第72回日本循環器学会
- Place of Presentation
  福岡匡際会議場
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-17209029
[Presentation] Dramatically Improved the Survival of Purified Mouse and Monkey ES Cel1-Derived Cardiomyocytes in Grafted Myocardium.2008
- Author(s)
  Hattori F, Onizuka T, Yuasa S, Shimoji K, Ohno Y, Hara M, Hao C, Fukuda K.
- Organizer
  第72回日本循環器学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-03-29
- Data Source
  KAKENHI-PROJECT-17209029
[Presentation] Wnt2 plays a key role in cardiac development via a non-canonical pathway.2008
- Author(s)
  0nizuka T, Yuasa S, Shimoji Ohno Y, Hattori F, Hara M, Hao C, Ogawa S, Fukuda K.
- Organizer
  第72回日本循環器学会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-03-28
- Data Source
  KAKENHI-PROJECT-17209029

1. YAMASHITA Hiromi (30594890)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
2. SASAKI Erika (70390739)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. OUGINO Yasuyuki (20598916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ITO Toshio (20106644)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUKUDA Keiichi (20199227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. MURATA Mitsushige (30317135)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. YUASA Shinsuke (90398628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
8. TANIOKA Yoshikuni (10072406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉岡正豊 (30398630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 伊藤明日香 (20412538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 澤田俊輔 (60711075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 兒島由佳 (70720655)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hattori Fumiyuki 服部 文幸

HATTORI Fumiyuki 服部 文幸

Research Projects

Research Products

Co-Researchers

日本人嚢胞性線維症患者由来iPS細胞を用いた汎粘膜改善薬の探索

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヒトiPS細胞由来唾液腺幹細胞を用いた再生治療におけるTherapeutic time windowの同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

TGFβ1を用いたヒトiPS細胞由来心筋細胞による心臓再生医療の高度化Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

COVID-19における急激な病態悪化メカニズムの解明および予防ターゲットの提示

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of embryological maturation switch of cardiomyocytes and application to human iPS cell-derived cardiomyocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Validation of therapeutic efficacy of allogenic transplantation therapy using pluripotent stem stem cell-derived cardiomyocytes for myocardial infarction in non-human primate: common marmoset.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fabrication and Transplantation of Common Marmoset ES cells-derived cardiomyocyte-sheetsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of regeneration, purification, and transplantation of cardiomyocytes from mouse and common marmoset ES cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Possible internal viral shedding and interferon production after clinical recovery from COVID-19: Case report2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct Metabolic Flow Enable Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct iPS Cells shows different Cardiac Differentiation Efficiency.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium.2010

Author(s)

Journal Title

Data Source

[Journal Article] Strategies for ensuring that regenerative cardiomyocytes function properly and in cooperation with the host myocardium.2010

Author(s)

Journal Title

Data Source

[Journal Article] Common marmoset embryonic stem cell can differentiate into Cardiomyocytes.2008

Author(s)

Journal Title

Data Source

Hattori Fumiyuki 服部文幸

HATTORI Fumiyuki 服部文幸