Morone Nobuhiro 諸根信弘

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MORONE Nobuhiro 諸根信弘

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Researcher Number	50399680
Other IDs
Affiliation (Current)	2025: 京都大学, 高等研究院, 客員教授
Affiliation (based on the past Project Information) *help	2017: 京都大学, 高等研究院, 客員教授 2016: 京都大学, 物質~細胞統合システム拠点, 教授 2016: 京都大学, 物質－細胞統合システム拠点, 教授 2015 – 2016: 京都大学, 物質－細胞統合システム拠点, 客員教授 2015: 京都大学, 学内共同利用施設等, 教授 … More 2015: 京都大学, 物質一細胞統合システム拠点, 客員教授 2014: 京都大学, 物質-細胞統合システム拠点, 特定拠点講師 2010 – 2014: 京都大学, 物質-細胞統合システム拠点, 講師 2013: 京都大学, 物質ー細胞統合システム拠点, 特定拠点講師 2011: 京都大学, 物質・細胞システム拠点, 講師 2009: National Center of Neurology and Psychiatry, 神経研究所微細構造研究部, 室長 2008: National Center of Neurology and Psychiatry, 神経研究所・微細構造研究部, 室長 2007 – 2008: National Center of Neurology and Psychiatry, 神経研究所微細構造研究部, 室長 Less
Review Section/Research Field	Principal Investigator Nanobioscience / Nanomaterials/Nanobioscience / Complex systems / Neurochemistry/Neuropharmacology Except Principal Investigator Dermatology / Physical pharmacy / Neurophysiology and muscle physiology
Keywords	Principal Investigator カベオラ / 細胞膜 / １分子科学 / エンドサイトーシス / 1分子科学 / 膜骨格 / 電子顕微鏡法 / クラスリン被覆ピット / アクチン膜骨格 / 分化 … More / 幹細胞 / 細胞 / 水和エネルギー / 化学エネルギー / 電子顕微鏡像 / 画像処理技術 / 力学的刺激 / 細胞膜構造 / タンパク質構造 / 反応中間状態 / ATP変換 / エネルギー論 / 電顕画像処理 / 蛋白質 / 細胞・組織 / タンパク質 / 脳神経疾患 … More Except Principal Investigator バリアー / プロテアーゼ / アトピー性皮膚炎 / 細胞 / 保湿 / skin / differentiation / barrier / stratum granulosum / epidermis / ケラチン / イメージング / 細胞死 / バリア / 角質層 / 表皮 / 皮膚 / electron microscopy / transfection / endocytosis / drug delivery / Electron microscopy / トランスフェクション / エンドサイトーシス / ドラッグデリバリー / 電子顕微鏡 / 小胞体 / 悪性高熱 / 相互作用 / カルシウムチャネル / 筋小胞体 / リアノジン受容体 Less

Molecular structure mechanism of caveolae membrane coatsPrincipal Investigator
- Principal Investigator
  
  MORONE NOBUHIRO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nanobioscience
- Research Institution
  Kyoto University
'Deep-etch' electron microscopic analysis of the actual mechanism of entry of cell-penetrating nanoparticles used for drug and gene-delivery into living cells
- Principal Investigator
  
  Heuser John
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
Analysis of moisturization mechanism of stratum corneusm
- Principal Investigator
  
  Matsui Takeshi
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Institute of Physical and Chemical Research
Structural Changes by Plasma Membrane DifferentiationPrincipal Investigator
- Principal Investigator
  
  MORONE Nobuhiro
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Nanomaterials/Nanobioscience
- Research Institution
  Kyoto University
エネルギー状態と顕微構造に基づく相補的解析法の開発Principal Investigator
- Principal Investigator
  
  諸根信弘
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyoto University
  National Center of Neurology and Psychiatry
Regulation of ryanodine receptor channel by interdomain interaction
- Principal Investigator
  
  MURAYAMA Takashi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Juntendo University
Three-dimensional structural analysis of Creutzfeldt-Jakob disease-related moleculesPrincipal Investigator
- Principal Investigator
  
  MORONE Nobuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  National Center of Neurology and Psychiatry

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 「透過型電子顕微鏡法:組織・細胞の3次元メゾスケール構造解析」(先端バイオマテリアルハンドブック)2012
- Author(s)
  和久井文、河野朋子、青山一弘、諸根信弘
- Publisher
  株式会社エヌ・ティー・エス
- Data Source
  KAKENHI-PROJECT-23310087
[Journal Article] Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency2017
- Author(s)
  Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser J, Yamada Y, Yamanaka S, Yamamoto T.
- Journal Title
  
  Cell Metabolism
  
  Volume: 印刷中 Issue: 5 Pages: 1103-1117.e6
- DOI
  10.1016/j.cmet.2017.04.017
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26286027
[Journal Article] Polymer-Coated pH-Responsive High-Density Lipoproteins2016
- Author(s)
  Hyungjin Kim, Haruki Okamoto,Arnaud E Felber, Anna Polomsak, Nobuhiro Morone, John E Heuser, Jean-Christophe Leroux, Tatsuya Murakami
- Journal Title
  
  J. Control. Release
  
  Volume: 228 Pages: 132-140
- DOI
  10.1016/j.jconrel.2016.03.005
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870301, KAKENHI-PUBLICLY-15H00811, KAKENHI-PROJECT-26286027
[Journal Article] Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.2016
- Author(s)
  Fujiwara TK, Iwasawa K, Kalay Z, Tsunoyama TA, Watanabe Y, Umemura YM, Murakoshi H, Suzuki KG, Nemoto YL, Morone N, Kusumi A.
- Journal Title
  
  Mol Biol Cell
  
  Volume: 27 Pages: 1101-19
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26286027
[Journal Article] Metabolic reprogramming during neuronal differentiation.2016
- Author(s)
  Agostini M, Romeo F, Inoue S, Niklison-Chirou MV, Elia AJ, Dinsdale D, Morone N, Knight RA, Mak TW, Melino G.
- Journal Title
  
  Cell Death Differ.
  
  Volume: 23 Issue: 9 Pages: 1502-14
- DOI
  10.1038/cdd.2016.36
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26286027
[Journal Article] Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane2016
- Author(s)
  T. K. Fujiwara, Iwasawa, K., Kalay, Z., Tsunoyama, T. A. Y. Watanabe, Y. M. Umemura, H. Murakoshi, K. G. N. Suzuki, Y. L., Nemoto, N. Morone, A. Kusumi
- Journal Title
  
  Mol. Cell Biol.
  
  Volume: 27 Issue: 7 Pages: 1101-1119
- DOI
  10.1091/mbc.e15-04-0186
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K14477, KAKENHI-PROJECT-15H04351, KAKENHI-PROJECT-13F03404, KAKENHI-PROJECT-26670138, KAKENHI-PUBLICLY-15H01212, KAKENHI-PUBLICLY-16H01358, KAKENHI-PROJECT-26286027, KAKENHI-PROJECT-26291031
[Journal Article] The modeling of Alzheimer's disease by the overexpression of mutant Presenilin 1 in human embryonic stem cells.2016
- Author(s)
  Honda M, Minami I, Tooi N, Morone N, Nishioka H, Uemura K, Kinoshita A, Heuser JE, Nakatsuji N, Aiba K.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 469 Issue: 3 Pages: 587-92
- DOI
  10.1016/j.bbrc.2015.12.025
- NAID
  120005980892
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253004, KAKENHI-PROJECT-26286027
[Journal Article] Thermosensitive Ion Channel Activation in Single Neuronal Cells by Using Surface-Engineered Plasmonic Nanoparticles.2015
- Author(s)
  Nakatsuji H, Numata T, Morone N, Kaneko S, Mori Y, Imahori H, Murakami T.
- Journal Title
  
  Angewandte Chemie International Edition
  
  Volume: 54 Issue: 40 Pages: 11725-1729
- DOI
  10.1002/anie.201505534
- NAID
  120005646471
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08197, KAKENHI-PUBLICLY-15H00811, KAKENHI-PROJECT-25220801, KAKENHI-PROJECT-24300162, KAKENHI-PROJECT-26286027
[Journal Article] Diffusion-coupled molecular assembly: structuring of coordination polymers across multiple length scales.2014
- Author(s)
  Hirai K, Reboul J, Morone N, Heuser JE, Furukawa S, Kitagawa S.
- Journal Title
  
  J Am Chem Soc.
  
  Volume: 136 Issue: 42 Pages: 14966-14973
- DOI
  10.1021/ja507971r
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26286027
[Journal Article] Regulation of cargo-selective endocytosis by dynamin 2 GTPase-activating protein girdin.2014
- Author(s)
  Liang Weng, Atsushi Enomoto, Hiroshi Miyoshi, Kiyofumi Takahashi, Naoya Asai, Nobuhiro Morone, Ping Jiang, Jian An, Takuya Kato, Keisuke Kuroda, Takashi Watanabe, Masato Asai, Maki Ishida-Takagishi, Yoshiki Murakumo, Hideki Nakashima, Kozo Kaibuchi and Masahide Takahashi.
- Journal Title
  
  EMBO Journal.
  
  Volume: 33 Issue: 18 Pages: 2098-2112
- DOI
  10.15252/embj.201488289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J40134, KAKENHI-PLANNED-22117005, KAKENHI-PROJECT-24390095, KAKENHI-PROJECT-24689021, KAKENHI-PROJECT-25430118, KAKENHI-PROJECT-25830078, KAKENHI-PROJECT-26253024, KAKENHI-PROJECT-26286027, KAKENHI-PROJECT-26670188, KAKENHI-PROJECT-26860261, KAKENHI-PROJECT-26221304, KAKENHI-PROJECT-25460493
[Journal Article] Helical DNA origami tubular structures with various sizes and arrangements2014
- Author(s)
  M. Endo, S. Yamamoto, T. Emura, K. Hidaka, N. Morone, J. E. Heuser, H. Sugiyama
- Journal Title
  
  Angewandte Chemie, International Edition
  
  Volume: 53 Issue: 29 Pages: 7484-7490
- DOI
  10.1002/anie.201402973
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24310097, KAKENHI-PROJECT-26286027, KAKENHI-PROJECT-26620133, KAKENHI-PLANNED-24104002, KAKENHI-PROJECT-24225005
[Journal Article] Mesoscopic Metal Nanoparticles Doubly Functionalized with natural and engineered lipidic dispersants for therapeutics2014
- Author(s)
  Murakami, T., Nakatsuji, H., Morone, N., Heuser, J. E., Ishidate, F., Hashida, M., Imahori, H.
- Journal Title
  
  ACS Nano
  
  Volume: 8 Issue: 7 Pages: 7370-7376
- DOI
  10.1021/nn5024818
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24300162, KAKENHI-PROJECT-25253004, KAKENHI-PROJECT-26286027, KAKENHI-PUBLICLY-25104514
[Journal Article] Exclusive Photothermal Heat Generation by a Gadolinium Bis(naphthalocyanine) Complex and Inclusion into Modified High-Density Lipoprotein Nanocarriers for Therapeutic Applications2013
- Author(s)
  Mathew S, Murakami T, Nakatsuji H, Okamoto H, Morone N, Heuser JE, Hashida M, Imahori H.
- Journal Title
  
  ACS Nano.
  
  Volume: 7(10) Issue: 10 Pages: 8908-16
- DOI
  10.1021/nn403384k
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-24300162, KAKENHI-PROJECT-24650263, KAKENHI-PUBLICLY-25104514, KAKENHI-PROJECT-25253004
[Journal Article] Development of a reentrant arrhythmia model in human pluripotent stem cell-derivpd cardiac cell sheets2013
- Author(s)
  Kadota S, et al.
- Journal Title
  
  European Heart Journal
  
  Volume: VOL.34 Issue: 15 Pages: 1147-1156
- DOI
  10.1093/eurheartj/ehs418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J07076, KAKENHI-PROJECT-21340120, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23710269
[Journal Article] Biocompatible fluorescent silicon nanocrystals for single-molecule tracking and fluorescence imaging2013
- Author(s)
  Nishimura H, Ritchie K, Kasai RS, Morone N, Sugimura H, Tanaka K, Sase I, Yoshimura A, Nakano Y, Fujiwara TK, and Kusumi A
- Journal Title
  
  J Cell Biol.
  
  Volume: 202 Issue: 6 Pages: 967-83
- DOI
  10.1083/jcb.201301053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23657101, KAKENHI-PUBLICLY-24115510, KAKENHI-PUBLICLY-24115511, KAKENHI-PROJECT-24247029, KAKENHI-PROJECT-24770120
[Journal Article] Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery2012
- Author(s)
  Tanaka T., Takahashi K., Yamane M., Tomida S., Nakamura S., Oshima K., Niwa A., Nishikomori R., Kambe N., Hara H., Mitsuyama M., Morone N., Heuse J.E., Yamamoto T., Watanabe A., Sato-Otsubo A., Ozawa S., Asaka I., Heike T., Yamanaka S., Nak
- Journal Title
  
  Blood
  
  Volume: 120(6) Issue: 6 Pages: 1299-308
- DOI
  10.1182/blood-2012-03-417881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22249042, KAKENHI-PROJECT-22390213, KAKENHI-PROJECT-22790283, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23390280, KAKENHI-PROJECT-23657147, KAKENHI-PROJECT-24390263, KAKENHI-PROJECT-24590524, KAKENHI-PROJECT-24659496
[Journal Article] Membrane mechanisms for signal transduction : The coupling of the meso-scale raft domains to membrane-skeleton-induced compartments and dynamic protein complexes2012
- Author(s)
  A.Kusumi, T.K.Fujiwara, N.Morone, K.J.Yoshida, R.Chadda, M.Xie, R.S.Kasai, K.G.N.Suzuki
- Journal Title
  
  Semin.Cell.Dev.Biol.
  
  Volume: 23(2) Issue: 2 Pages: 126-144
- DOI
  10.1016/j.semcdb.2012.01.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247022, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23657101, KAKENHI-PROJECT-24247029, KAKENHI-PROJECT-24370055
[Journal Article] A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions2012
- Author(s)
  Minami I, Yamada K, Otsuji TG, Yamamoto T, Shen Y, Otsuka S, Kadota S, Morone N, Barve M, Asai Y, Tenkova-Heuser T, Heuser JE, Uesugi M, Aiba K, Nakatsuji N
- Journal Title
  
  Cell Rep
  
  Volume: 2(5) Issue: 5 Pages: 1448-60
- DOI
  10.1016/j.celrep.2012.09.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23500446, KAKENHI-PROJECT-23710269, KAKENHI-PROJECT-24790755
[Journal Article] Cells respond to mechanical stress by rapid disassembly of caveolae2011
- Author(s)
  Sinha B, Koster D, Ruez R, Gonnord P, Bastiani M, Abankwa D, Stan RV, Butler-Browne G, Vedie B, Johannes L, Morone N, Parton RG, Raposo G, Sens P, Lamaze C, Nassoy P
- Journal Title
  
  Cell.
  
  Volume: 144(3) Issue: 3 Pages: 402-13
- DOI
  10.1016/j.cell.2010.12.031
- Data Source
  KAKENHI-PROJECT-23310087
[Journal Article] Submembranous septins as relatively stable components of actin-based membrane skeleton2011
- Author(s)
  A.Hagiwara, Y.Tanaka, R.Hikawa, N.Morone, A.Kusumi, H.Kimura, M.Kinoshita
- Journal Title
  
  Cytoskeleton
  
  Volume: 68 Issue: 9 Pages: 512-525
- DOI
  10.1002/cm.20528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21247022, KAKENHI-PROJECT-21570196, KAKENHI-PROJECT-23310087, KAKENHI-PROJECT-23370084
[Journal Article] Fractal dimension analysis and mathematical morphology of structural changes in actin filaments imaged by electron microscopy2011
- Author(s)
  Kimori, Y., E. Katayama, N. Morone, and T. Kodama
- Journal Title
  
  J. Struct. Biol
  
  Volume: 176 Issue: 1 Pages: 1-8
- DOI
  10.1016/j.jsb.2011.07.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370061, KAKENHI-PROJECT-23310087
[Journal Article] Single-moleculefluorescence polarization study ofconformational change in archaeal group II chaperonin2011
- Author(s)
  Ryo Iizuka, Taro Ueno, Nobuhiro Morone, and Takashi Funatsu
- Journal Title
  
  PLoS ONE
  
  Volume: 6 Issue: 7 Pages: e22253-e22253
- DOI
  10.1371/journal.pone.0022253
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370065, KAKENHI-PUBLICLY-22020006, KAKENHI-PROJECT-23310087
[Journal Article] Cells respond to mechanical stress by rapid disassembly of caveolae.2010
- Author(s)
  Sinha B, Koster D, Ruez R, Gonnord P, Bastiani M, Abankwa D, Stan RV, Butler-Browne G, Vedie B, Johannes L, Morone N, Parton RG, Raposo G, Sens P, Lamaze C, Nassoy P.
- Journal Title
  
  Cell
  
  Volume: 144 Pages: 402-413
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21118523
[Journal Article] Extended morphological processing : a practical method for automatic spot detection of biological markers from microscopic images.2010
- Author(s)
  Kimori Y, Baba N, Morone N.
- Journal Title
  
  BMC Bioinformatics
  
  Volume: 11 Pages: 373-373
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21118523
[Journal Article] Freeze-etch electron tomography for the plasma membrane interface.2010
- Author(s)
  Morone N.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 657 Pages: 275-286
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21118523
[Journal Article] Nitric oxide release in human aortic endothelial cells mediated by deliveryof amphiphilic polysiloxane nanoparticles to caveolae.2009
- Author(s)
  Nishikawa T, Iwakiri N, Kaneko Y, Taguchi A, Fukushima K, Mori H, Morone N, Kadokawa J.
- Journal Title
  
  Biomacromolecule 10
  
  Pages: 2074-85
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21118523
[Journal Article] Structural Analysis of Cell Membranes by Small Convergence Angle HAADF-STEM Tomography.2009
- Author(s)
  Morone N, Aoyama K.
- Journal Title
  
  Kenbikyo 44
  
  Pages: 257-261
- NAID
  130007788939
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21118523
[Journal Article] Extraction of structural features of biological images and its evaluationby mathematical morphology2009
- Author(s)
  Kimori Y, Morone N, Katayama E.
- Journal Title
  
  Kenbikyo 44
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-21118523
[Journal Article] Three-dimensional molecular architecture of the plasma-membrane-associated cytoskeleton as reconstructed by freeze-etch electron tomography2008
- Author(s)
  Morone N
- Journal Title
  
  Methods Cell Biol. 88
  
  Pages: 207-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500339
[Journal Article] athematical morphology に基づくバイオイメージからの構造情報の抽出解析2008
- Author(s)
  木森義隆, 諸根信弘, 片山栄作
- Journal Title
  
  顕微鏡 44
  
  Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500339
[Journal Article] Engineering a novel multifunctional green fluorescent protein tag for a wide variety of protein research.2008
- Author(s)
  Kobayashi T, Morone N, Kashiyama T, Oyamada H, Kurebayashi N, Murayama T.
- Journal Title
  
  PLoS ONE 3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500339
[Journal Article] Three-dimensional molecular architecture of the plasma-membrane-associated cytoskeleton as reconstructed by freeze-etch electron tomography.2008
- Author(s)
  Morone N, Nakada C, Umemura Y, Usukura J, Kusumi A.
- Journal Title
  
  Methods Cell Biol. 88
  
  Pages: 207-36
- Data Source
  KAKENHI-PROJECT-19500339
[Journal Article] 電子線<フリーズレプリカ>トモグラフィー法による細胞膜骨格の3次元イメージング2007
- Author(s)
  諸根信弘
- Journal Title
  
  顕微鏡 42
  
  Pages: 150-154
- NAID
  10020010056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] 細胞やタンパク質分子複合体の無氷晶凍結に必要な基礎原理と方法論2016
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2016-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] Profound plasma membrane changes caused by acute cholesterol elevation2015
- Author(s)
  Azumi Yoshimura, Silvia Pujals, Nobuhiro Morone, Tanya Tenkova and John Heuser
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25253004
[Presentation] Three dimensional structure of ring-shaped membrane skeleton in axon2015
- Author(s)
  Kuwahara R, Aoyama K, Mitsuoka K and Morone N.
- Organizer
  日本顕微鏡学会第７１回学術講演会
- Place of Presentation
  京都、日本
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] Cryo-STEM Tomography による細胞構造の3次元解析2015
- Author(s)
  青山一弘, 諸根信弘, 桒原隆亮, 横山佳奈, 光岡薫
- Organizer
  日本顕微鏡学会第７１回学術講演会
- Place of Presentation
  京都、日本
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] カベオラと細胞膜の相互作用点に関する構造解析的検証2015
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会第７１回学術講演会
- Place of Presentation
  京都、日本
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] プラズモンナノ材料による1神経細胞の熱感受性イオンチャネルの光活性化2015
- Author(s)
  村上達也, 中辻博貴, 沼田朋大, 諸根信弘, 金子周司, 森泰生, 今堀博
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] 神経軸索内膜骨格の3次元構造2015
- Author(s)
  桒原隆亮, 青山一弘, 光岡薫, 諸根信弘
- Organizer
  日本顕微鏡学会第７１回学術講演会
- Place of Presentation
  京都、日本
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] 感染性タンパク質結晶化の細胞内メゾ構造解析2015
- Author(s)
  諸根信弘, 森肇, Heuser John
- Organizer
  日本顕微鏡学会第７１回学術講演会
- Place of Presentation
  京都、日本
- Year and Date
  2015-05-13
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] Three dimensional structure of cytoskeleton in axon.2015
- Author(s)
  Kuwahara R, Yokoyama K, Aoyama K, Mitsuoka K and Morone N.
- Organizer
  The 2nd East-Asia Microscopy Conference
- Place of Presentation
  姫路、日本
- Year and Date
  2015-11-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] チュートリアル：フリーズエッチングの基礎と実践2013
- Author(s)
  諸根信弘、ホイザー・ジョン
- Organizer
  日本顕微鏡学会第69回学術講演会
- Place of Presentation
  ホテル阪急エキスポパーク、大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Three findings by electron microscopy in caveolar research2013
- Author(s)
  Morone N
- Organizer
  JSM-MPFI Joint-Seminar 2013
- Place of Presentation
  Max Plang Florida Institute for Neuroscience, FL, USA
- Year and Date
  2013-12-27
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] チュートリアル：凍結割断の像の読み方2013
- Author(s)
  諸根信弘、ホイザー・ジョン
- Organizer
  日本顕微鏡学会第69回学術講演会
- Place of Presentation
  ホテル阪急エキスポパーク、大阪
- Invited
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Cavin/PTRF regulates caveolar endocytosis by forming "crescents" that girdle caveolae, stabilizes them in relatively flat conformations, and links them to actin-membrane skeletons (2)2013
- Author(s)
  Morone N
- Organizer
  14th International Membrane Research Forum
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Dendra融合タンパク質によるカベオラの急速凍結・ディープエッチ電子顕微鏡法2013
- Author(s)
  諸根信弘、吉村安寿弥、ホイザー・ジョン
- Organizer
  日本顕微鏡学会第69回学術講演会
- Place of Presentation
  大阪
- Year and Date
  2013-05-20
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Dendra融合タンパク質によるカベオラの急速凍結・ディープエッチ電子顕微鏡法2013
- Author(s)
  諸根信弘、吉村安寿弥、ホイザー・ジョン
- Organizer
  日本顕微鏡学会第69回学術講演会
- Place of Presentation
  ホテル阪急エキスポパーク、大阪
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] キャビンとカベオラ分子構築に関する構造解析的検証2013
- Author(s)
  諸根信弘、ロブ・パートン、ジョン・ホイザー
- Organizer
  第65回日本細胞生物学会大会
- Place of Presentation
  ウィンクあいち
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Three findings by electron microscopy in caveolar research2013
- Author(s)
  Morone N.
- Organizer
  JSM-MPFI Joint-Seminar 2013
- Place of Presentation
  Max Plank Florida Institute for Neuroscience, FL-USA
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Discovery-based science by electron microscopy2013
- Author(s)
  諸根信弘
- Organizer
  九州工業大学第4回バイオイメージングセミナー
- Place of Presentation
  九州工業大学、福岡
- Invited
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] カベオラの被覆構造と分子構築：ディープエッチ電子顕微鏡法による解析2012
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会関西支部特別講演会
- Place of Presentation
  京都、日本
- Invited
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] カベオラダイナミクス：免疫ディープエッチ電子顕微鏡法による可視化解析2012
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会生体構造解析分科会・北海道大学理学部合同セミナー
- Place of Presentation
  北海道、日本
- Invited
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Cavin regulates caveolar endocytosis by forming crescents that girdle caveolae, stabilizes then in relatively flat conformations, and links them to actin-membrane skeleton2012
- Author(s)
  Morone N
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, USA
- Year and Date
  2012-12-17
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Plasma membrane differentiation during adipogenesis : Freeze-etch electron microscopy for caveolar architecture2012
- Author(s)
  Morone N
- Organizer
  JSM-NUS Joint-Seminar 2011
- Place of Presentation
  National University of Singapore, Singapore
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Caveolar dynamics and molecular architectures2012
- Author(s)
  Morone N
- Organizer
  EM functional imaging workshop 2012 at NIPS  "Cutting-edge technology for functional bio-imaging at higher-dimensions"
- Place of Presentation
  Aichi, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Plasma membrane differentiation during adipogenesis : Freeze-etch electron microscopy for caveolar architecture2012
- Author(s)
  Morone N
- Organizer
  Joint Seminar(日本顕微鏡学会生体構造分析分科会-国立シンガポール大学)
- Place of Presentation
  国立シンガポール大学(シンガポール)(招待講演)
- Year and Date
  2012-01-13
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Cavin regulates caveolar endocytosis by forming "crescents" that girdle caveolae, stabilizes them in relatively flat conformations, and links them to cortical actin filaments2012
- Author(s)
  Morone N
- Organizer
  2012 Annual Meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Evidence that the protein cavin negatively regulates caveolar endocytosis by forming "crescents" that girdle caveolae, stabilize them in relatively flat conformations, and link them to cortical actin filaments2012
- Author(s)
  Morone N
- Organizer
  CLS-iCeMS Joint Symposium
- Place of Presentation
  Beijing, China
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Cellular EM aspects in caveolar dynamics2011
- Author(s)
  諸根信弘
- Organizer
  第67回日本顕微鏡学会学術講演会
- Place of Presentation
  福岡国際会議場(福岡県)
- Year and Date
  2011-05-16
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Plasma membrane differentiation during adipogenesis : cellular electron structural analysis by rapid-freeze, deep-etch, platinum-replica EM.2011
- Author(s)
  Morone N.
- Organizer
  大阪大学蛋白質研究所セミナー
- Place of Presentation
  大阪大学蛋白質研究所
- Year and Date
  2011-02-17
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] Plasma Membrane Architecture Reconstructed By Small Convergence-Angle HAADF-STEM Freeze-etch Tomography : Improvement of the Quality in Tomogram2011
- Author(s)
  Morone N, Heuser J, Aoyama K
- Organizer
  EMBL Conference : Sixth International Congress on Electron Tomography
- Place of Presentation
  ハイデルベルグ(ドイツ)
- Year and Date
  2011-05-06
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] カベオラ動態の細胞電子顕微鏡解析2011
- Author(s)
  諸根信弘
- Organizer
  第63回日本細胞生物学会大会(ワークショップ)
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-23310087
[Presentation] Plasma membrane differentiation during adipogenesis : electron structural analysis by rapid-freeze, deep-etch EM.2010
- Author(s)
  Morone N.
- Organizer
  日本電子顕微鏡学会関西支部特別講演会
- Place of Presentation
  名古屋大学野依記念学術交流館(招待講演)
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] Three-dimensional reconstruction of the membrane skeletonat the interface by freeze-etch electron tomography.(招待講演)2010
- Author(s)
  Morone N.
- Organizer
  Progress Report Symposium of Membrane Mechanism Project (2005-2010), ICORP, JST
- Place of Presentation
  ホテルフジタ京都、Kyoto
- Year and Date
  2010-01-29
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] Structural analysis for cell membrane domain by electron microscopic image processing.2010
- Author(s)
  Kimori Y, Morone N.
- Organizer
  The 13th International Membrane Research Forum The 6th iCeMS International Symposium
- Place of Presentation
  ホテルフジタ京都、Kyoto
- Year and Date
  2010-01-28
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] 細胞膜につくられたコンパートメント構造:フリーズフラクチャー解析と画像認識技術による可視化(招待講演)2009
- Author(s)
  木森義隆、諸根信弘
- Organizer
  日本顕微鏡学会第65回学術講演会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2009-05-26
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] 生物顕微鏡と凍結技法2009
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会第53回シンポジウム
- Place of Presentation
  東京工業大学、東京
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] Freeze-etch Electron Tomography & Mathematical Morphological Analysis for the Plasma Membrane Interface.(招待講演)2009
- Author(s)
  Morone N.
- Organizer
  21st Annual Meeting of the KSMCB
- Place of Presentation
  COEX, Seoul Korea
- Year and Date
  2009-10-16
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] 新規多機能GFPを用いたリアノジン受容体の構造機能解析2009
- Author(s)
  村山尚, 小林琢也, 樫山拓, 呉林なごみ, 木森義隆, 諸根信弘, 北井敏幸, 高萩隆行, 櫻井隆
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-21500383
[Presentation] 数理形態学に基づいた新しい画像処理理論:細胞内タンパク質の定量分布解析へ2009
- Author(s)
  木森義隆、湯浅茂樹、諸根信弘
- Organizer
  日本顕微鏡学会第65回学術講演会
- Place of Presentation
  仙台国際センター、仙台
- Year and Date
  2009-05-26
- Data Source
  KAKENHI-PUBLICLY-21118523
[Presentation] The structural interplay between the plasma membrane and cytoskeletons in neural svstems: a deep-etch EM research2008
- Author(s)
  N.Morone
- Organizer
  The 38th Seiriken/Sokendai International Conference, "Stock and flow of functional molecules in svnapse"
- Place of Presentation
  Okazaki Japan
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] GPI-anchored Protein's complex and membrane skeleton in human neural progenitors as revealed by electron microscopy.2008
- Author(s)
  Morone N, Wakui F, Kohno T, Kimori Y, Yuasa S.
- Organizer
  The 48th annual meeting of the American Society for Cell Biology
- Place of Presentation
  Francisco USA.
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] 電子線<フリーズレプリカ>トモグラフィー法で細胞膜構造を3次元解析する2008
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会関東支部講演会
- Place of Presentation
  目黒東京
- Year and Date
  2008-03-08
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] GPI-Anchored Protein And Membrane Structure Inside Human Neural Progenitors.2008
- Author(s)
  Morone N, Wakui F, Kohno T, Yamamura T, Satoh J, and Yuasa S.
- Organizer
  The 5^<th> international Forum on Oxidative Stress and Aging
- Place of Presentation
  Ancona Italy.
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] GPI-Anchored Protein And Membrane Structure Inside Human Neural Progenitors2008
- Author(s)
  Morone N
- Organizer
  The 5^<th> international Forum on Oxidative Stress and Aging
- Place of Presentation
  Ancona Italy
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] Electron freeze-replica tomography correlated with a single-moleculeimaging: a structural analysis for the plasma membrane2008
- Author(s)
  N.Morone
- Organizer
  The First iCeMS International Symposium The Eleventh MEMBRANE RESEARCH FORUM
- Place of Presentation
  Kyoto Japan
- Year and Date
  2008-02-20
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] GPI-anchored Protein's complex and membrane skeleton in human neural progenitors as revealed by electron microscopy2008
- Author(s)
  Morone N
- Organizer
  The 48th annual meeting of the American Society for Cell Biology
- Place of Presentation
  San Francisco USA
- Year and Date
  2008-12-14
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] 細胞膜インターフェイスの構造組織化2007
- Author(s)
  諸根信弘
- Organizer
  日本顕微鏡学会生体構造解析分科会2007年度研究討論会VII
- Place of Presentation
  晴海東京
- Year and Date
  2007-12-20
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] Electron tomography reveals the plasma membrane compartmentalizatiorn as its three dimensional interplay between membrane and cytoskeletal systems2007
- Author(s)
  N.Morone
- Organizer
  The American Sodety for Cell Biology & Euro pean Cytoskeleton Forum
- Place of Presentation
  Dijon France
- Year and Date
  2007-06-28
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] Three-dimensional reconstruction of the membrane skeleton lust beneath the plasma membrane by electron tomography2007
- Author(s)
  N.Morone, T.K.Fujiwara, K.Murase, R.S.Kasai, H.Ike, S.Yuasa, J.Usukura, and A.Kusumi
- Organizer
  Biochemistry and Molecular Biology 2007
- Place of Presentation
  Yokohama Japan
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] GPI-anchored protein localizes with 14-3-3 and HSP60 on the mitochondria in human neural progenitors2007
- Author(s)
  N.Morone, J.Satoh, F.Wakui, T.Yamamura, S.Yuasa
- Organizer
  American Society for Cell Biology 47th Amual Meeting
- Place of Presentation
  Washington DC, USA
- Year and Date
  2007-12-05
- Data Source
  KAKENHI-PROJECT-19500339
[Presentation] Mesoscale organization of insect virus-polyhedra crystals revealed by rapid-freeze, freeze-fracture EM
- Author(s)
  Morone N, Mori Hajime, Heuser J.
- Organizer
  18th International Microscopy Congress
- Place of Presentation
  Prague, Czech
- Year and Date
  2014-09-07 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] Insect virus-polydhedra crystals revealed by tepid-freeze, freeze-fracture EM.
- Author(s)
  Morone N, Mori Hajime, Heuser J.
- Organizer
  日本顕微鏡学会第７０回記念学術講演会
- Place of Presentation
  幕張、日本
- Year and Date
  2014-05-11 – 2014-05-13
- Data Source
  KAKENHI-PROJECT-26286027
[Presentation] Intracellular crystallization of insect virus and polyhedra revealed by quick-freeze, freeze-fracture electron microscopy.
- Author(s)
  Morone N, Mori Hajime, Heuser J.
- Organizer
  The 2014 ASCB/ ifcb meeting
- Place of Presentation
  Fohiladelphia, USA
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-26286027

1. HEUSER John (40571815)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
2. MURAYAMA Takashi (10230012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. KUREBAYASHI Nagomi (50133335)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKAHAGI Takayuki (40271069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. UEHARA Akira (60140745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Murakami Tatsuya (90410737)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. Matsui Takeshi (10452442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TOYOOKA KIMINORI (10360596)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUJIWARA TAKAHIRO (80423060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. NUMATA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. OSHIMA Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. NIWA Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. SUZUKI KEenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. KIM HYUNGJIN

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 楠見明弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 遠藤政幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 片山栄作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 船津高志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morone Nobuhiro 諸根 信弘

MORONE Nobuhiro 諸根 信弘

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Molecular structure mechanism of caveolae membrane coatsPrincipal Investigator

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'Deep-etch' electron microscopic analysis of the actual mechanism of entry of cell-penetrating nanoparticles used for drug and gene-delivery into living cells

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Analysis of moisturization mechanism of stratum corneusm

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Structural Changes by Plasma Membrane DifferentiationPrincipal Investigator

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エネルギー状態と顕微構造に基づく相補的解析法の開発Principal Investigator

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Regulation of ryanodine receptor channel by interdomain interaction

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Three-dimensional structural analysis of Creutzfeldt-Jakob disease-related moleculesPrincipal Investigator

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[Book] 「透過型電子顕微鏡法:組織・細胞の3次元メゾスケール構造解析」(先端バイオマテリアルハンドブック)2012

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[Journal Article] Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency2017

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[Journal Article] Polymer-Coated pH-Responsive High-Density Lipoproteins2016

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[Journal Article] Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane.2016

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[Journal Article] Metabolic reprogramming during neuronal differentiation.2016

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[Journal Article] Confined diffusion of transmembrane proteins and lipids induced by the same actin meshwork lining the plasma membrane2016

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[Journal Article] The modeling of Alzheimer's disease by the overexpression of mutant Presenilin 1 in human embryonic stem cells.2016

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NAID

Morone Nobuhiro 諸根信弘

MORONE Nobuhiro 諸根信弘