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OHKUMO Tsuyoshi  大雲 剛志

ORCIDConnect your ORCID iD *help
Researcher Number 50432505
Affiliation (based on the past Project Information) *help 2007 – 2011: 大阪大学, 蛋白質研究所, 助教
2009: 大阪大学, 生命機能研究科, 助教
2007: Osaka University, たんぱく質研究所, 助教
2006: 大阪大学, 生命機能研究科, 助手
Review Section/Research Field
Principal Investigator
Risk sciences of radiation/Chemicals
Except Principal Investigator
Neurochemistry/Neuropharmacology / Biological pharmacy
Keywords
Principal Investigator
DNAホリメラーゼ・イータ / 皮膚癌 / 紫外線 / 遺伝子ノックアウト / 損傷乗り越え複製 / DNAポリメラーゼ・イオタ / DNAポリメラーゼ・イータ / 色素性乾皮症バリアント
Except Principal Investigator
Sirtl / 視床下部 … More / Necdin / NSE3 / 6複合体 / SMC5 / アセチル化 / FoxOl / SMC5/6複合体 / FoxO1 / 哺乳類ニューロン / DNA修復 / エネルギー代謝 / SMC5/ 6複合体 / Fox01 / Sirt1 / 蛋白質ネットワーク / がん / 細胞周期 / クロマチン / ゲノム / 放射線 / DNA複製 / 癌 / 遺伝子 / アポトーシス / Cdc2 / 小脳顆粒神経細胞 / 介在ニューロン / 大脳基底核原基 / 脳由来神経栄養因子 / プラダー・ウィリー症候群 / 軸索伸長 / 接線方向移動 / 海馬 / Foxol / p53 / 大脳皮質 / ニューロン / ゲノムインプリンティング / 脳神経疾患 / 発現制御 / 発生・分化 / 神経科学 Less
  • Research Projects

    (4 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (5 People)
  •  Mechanisms maintaining neuronal survival via necdin-centered protein interaction networks

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  Cellular responses to inhibition of DNA replication fork progression at DNA lesions

    • Principal Investigator
      HANAOKA Fumio
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biological pharmacy
    • Research Institution
      Gakushuin University
      Osaka University
  •  Genomic imprinting-involved regulatory mechanisms of central nervous system development

    • Principal Investigator
      YOSHIKAWA Kazuaki
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Osaka University
  •  損傷乗り越え複製ポリメラーゼの発癌抑制メカニズムの解明Principal Investigator

    • Principal Investigator
      大雲 剛志
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (Start-up)
    • Research Field
      Risk sciences of radiation/Chemicals
    • Research Institution
      Osaka University

All 2012 2011 2010 2009 2007 2006

All Journal Article Presentation

  • [Journal Article] Necdin controls proliferation of white adipocyte progenitor cells2012

    • Author(s)
      Fujiwara K, Hasegawa K, Ohkumo T, Miyoshi H, Tseng Y-H, Yoshikawa K
    • Journal Title

      PLoS One

      Volume: 7(1)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Journal Article] Neural stem cell-like gene expression in a mouse ependymoma cell line transformed by human BK polyomavirus2011

    • Author(s)
      Aizawa T, Hasegawa K, Ohkumo T, Haga S, Ikeda K, Yoshikawa K
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 1 Pages: 122-129

    • DOI

      10.1111/j.1349-7006.2010.01775.x

    • NAID

      10029288727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Journal Article] UV-B radiation induces epithelial tumors in mice lacking DNA polymerase η and mesenchymal tumors in mice deficient for DNA polymerase ι.2006

    • Author(s)
      Ohkumo T et al.
    • Journal Title

      Molecular and Cellular Biology 26・20

      Pages: 7696-7706

    • Data Source
      KAKENHI-PROJECT-18810016
  • [Presentation] Epigenetic regulation of necdin gene expression during neural development2010

    • Author(s)
      大雲剛志
    • Organizer
      第53回神経化学会
    • Place of Presentation
      神戸コンベンションセンター
    • Year and Date
      2010-09-02
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Regulated expression of MAGE family genes during neural development2009

    • Author(s)
      大雲剛志
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      群馬県渋川市
    • Year and Date
      2009-06-22
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] Regulation of necdin expression by DNA methylation during neural development2009

    • Author(s)
      大雲剛志
    • Organizer
      第82回生化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2009-10-24
    • Data Source
      KAKENHI-PROJECT-21300138
  • [Presentation] 損傷乗り越え複製の分子機構-DNAポリメラーゼ・イータを中心に-2007

    • Author(s)
      花岡文雄、横井雅幸、大雲剛志、金尾梨絵、赤木純一、益谷央豪
    • Organizer
      第30回日本分子生物学会年会・第80回日本生化学会大会合同大会(BMB2007)、シンポジウム「DNA修復研究の最前線」
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-19209003
  • 1.  YOSHIKAWA Kazuaki (30094452)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 2.  NISHIMURA Isao (70362621)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  HANAOKA Fumio (50012670)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  MASUTANI Chikahide (40241252)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  HASEGAWA Koichi (20546783)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results

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