MATSUNO Kenji 松野研司

Researcher Number	50433214
Other IDs
Affiliation (Current)	2025: 安田女子大学, 薬学部, 教授 2025: 工学院大学, 先進工学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 安田女子大学, 薬学部, 教授 2017 – 2021: 工学院大学, 先進工学部, 教授 2015: 工学院大学, 先進工学部, 教授 2012 – 2014: 岡山大学, 医歯(薬)学総合研究科, 准教授 2013: 岡山大学, 大学院医歯薬学総合研究科, 准教授
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Drug development chemistry Except Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Basic Section 56010:Neurosurgery-related / Drug development chemistry
Keywords	Principal Investigator 抗がん剤 / 創薬 / 医薬化学 / 阻害剤 / 構造活性相関 / IDO / リード化合物 / ヘム / 免疫チェックポイント / キヌレニン … More / LSD2 / LSD1 / S1025 / S1024 / エピジェネティクス / LSD / 薬学 / 創薬化学 / ケミカルバイオロジー / 標的分子探索 / プローブ分子 / 細胞周期 / 評価系構築 / 新規ケモタイプ / 活性増強 / in vivo活性 / 免疫寛容 / がん免疫療法剤 … More Except Principal Investigator IDO / KNP-1 / シアノバクテリア / キヌレニン / メタボロミクス / がん免疫寛容 / cintirorgon / SR0987 / STAT1 / XY018 / TMP920 / インバースアゴニスト / RORγt / カウレルピン / センナリズタ / 免疫回避機構 / トリプトファン / グリオーマ / IFN-gamma / immunosupression / IDO inhibitor / glioblastoma / a mouse model / IFN-γ / imunosupression / malignant glioma / 低栄養 / がん / panaxcerol B / グルタミン / 栄養飢餓 / βアミノ酸 / リプログラミング / フェニルプロピオン酸 / NOTCH / secretase / γセクレターゼ / チアゾリジンジオン / プロピオン酸 / PPAR / アルツハイマー Less

Inhibitors of kynurenine production: drug development of non-conventional IDO1 inhibitor A and elucidation of mechanism of action by cpd B.Principal Investigator
- Principal Investigator
  
  松野研司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Yasuda Women's University
海洋生物由来新規キヌレニン産生阻害剤のがん免疫寛容抑制剤としての展開
- Principal Investigator
  
  大野修
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kogakuin University
LSD阻害剤の創製：LSD1阻害剤の創薬展開およびLSD2機能解明の基盤構築Principal Investigator
- Principal Investigator
  
  松野研司
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Yasuda Women's University
  Kogakuin University
Novel combination immunotherapy for glioma with new Tryptophan metabolizing enzyme inhibitor and Interferon
- Principal Investigator
  
  Kawataki Tomoyuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Yamanashi
Search for marine organisms-derived compounds that regulate the reprogramming mechanism of cancer cells
- Principal Investigator
  
  Ohno Osamu
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kogakuin University
Drug development of novel anti-mitotic agent with unique phenotype and elucidation of the mechanism of actionPrincipal Investigator
- Principal Investigator
  
  MATSUNO Kenji
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kogakuin University
Research on IDO inhibitor as anticancer agentPrincipal Investigator
- Principal Investigator
  
  MATSUNO KENJI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kogakuin University
  Okayama University
Explolation of gamma-secretase modulator based on metabolic nuclear receptor
- Principal Investigator
  
  HIROYUKI MIYACHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Okayama University

All 2024 2023 2022 2021 2020 2019 2018 2016 2015 2013 2012 Other

All Journal Article Presentation Patent

[Journal Article] Structure-activity relationship and in silico evaluation of cis- and trans-PCPA-derived inhibitors of LSD1 and LSD2.2022
- Author(s)
  Niwa, H.; Watanabe, C.; Sato, S.; Harada, T.; Watanabe, H.; Tabusa, R.; Fukasawa, S.; Shiobara, A.; Hashimoto, T.; Ohno, O.; Nakamura, K.; Tsuganezawa, K.; Tanaka, A.; Shirouzu, M.; Honma, T.; Matsuno, K.; Umehara, T.
- Journal Title
  
  ACS Med. Chem. Lett.
  
  Volume: 13 Issue: 9 Pages: 1485-1492
- DOI
  10.1021/acsmedchemlett.2c00294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06461, KAKENHI-PROJECT-20H03388, KAKENHI-PROJECT-20K21406
[Journal Article] Inhibition of lipopolysaccharide-induced inflammatory signaling by soft-coral-derived prostaglandin A2 in RAW264.7 cells2022
- Author(s)
  Osamu Ohno, Eika Mizuno, Junichiro Miyamoto, Tomoyuki Hoshina, Takuya Sano, Kenji Matsuno
- Journal Title
  
  Marine Drugs
  
  Volume: 20 Issue: 5 Pages: 316-316
- DOI
  10.3390/md20050316
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05295
[Journal Article] Isolation of caldorazole, a thiazole-containing polyketide with selective cytotoxicity under glucose-restricted conditions2022
- Author(s)
  Osamu Ohno, Arihiro Iwasaki, Kyouhei Same, Chihiro Kudo, Erika Aida, Kazuya Sugiura, Shimpei Sumimoto, Toshiaki Teruya, Etsu Tashiro, Siro Simizu, Kenji Matsuno, Masaya Imoto, Kiyotake Suenaga
- Journal Title
  
  Organic Letters
  
  Volume: 24 Issue: 25 Pages: 4547-4551
- DOI
  10.1021/acs.orglett.2c01566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05295, KAKENHI-PROJECT-21K14747, KAKENHI-PROJECT-19H02842, KAKENHI-PROJECT-20H02870, KAKENHI-PROJECT-20K05732
[Journal Article] Anti-apoptotic activity of methyl (3R,4E,6Z,15E)-3-hydroxyoctadecatrienoate in human cervical carcinoma HeLa cells2021
- Author(s)
  Osamu Ohno, Keigo Sato, Ryo Honma, Ruri Chiba, Kenji Matsuno
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 85 Issue: 2 Pages: 228-232
- DOI
  10.1093/bbb/zbaa006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05341
[Journal Article] Discovery of Carbono(di)thioates as Indoleamine 2,3-Dioxygenase 1 Inhibitors.2021
- Author(s)
  Kumazawa Miyuki、Tejima Manabu、Fukuda Miwa、Takeda Shota、Suzuki Kenji、Mizumoto Yukiko、Sato Kakeru、Waki Minoru、Miyachi Hiroyuki、Asai Akira、Takikawa Osamu、Hashimoto Tomoko、Ohno Osamu、Matsuno Kenji
- Journal Title
  
  ACS Medicinal Chemistry Letters
  
  Volume: 12 Issue: 2 Pages: 211-216
- DOI
  10.1021/acsmedchemlett.0c00527
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08371
[Journal Article] Inhibitory effects of biseokeaniamide A against lipopolysaccharide-induced signal transduction2020
- Author(s)
  Osamu Ohno, Takuro Terasaki, Takuya Sano, Yuki Hitomi, Junichiro Miyamoto, Kenji Matsuno,
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 11 Pages: 127069-127069
- DOI
  10.1016/j.bmcl.2020.127069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05341, KAKENHI-PROJECT-17K05862, KAKENHI-PROJECT-17K08371
[Journal Article] Design and Synthesis of 4-(2-Pyrrolyl)-4-phenylheptane Derivatives as Estrogen Receptor Antagonists2020
- Author(s)
  Tsuji Genichiro、Demizu Yosuke、Naganuma Miyako、Yokoo Hidetomo、Misawa Takashi、Matsuno Kenji
- Journal Title
  
  HETEROCYCLES
  
  Volume: 101 Issue: 2 Pages: 429-429
- DOI
  10.3987/com-19-14121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08385, KAKENHI-PROJECT-17K08371
[Journal Article] Selective Inhibition of Spindle Microtubules by a Tubulin-Binding Quinazoline Derivative2019
- Author(s)
  Sawada Jun-ichi、Ishii Hirosuke、Matsuno Kenji、Sato Masayuki、Suzuki Yumiko、Asai Akira
- Journal Title
  
  Molecular Pharmacology
  
  Volume: 96 Issue: 5 Pages: 609-618
- DOI
  10.1124/mol.119.116624
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08371, KAKENHI-PROJECT-18K06587, KAKENHI-PROJECT-18H02559
[Journal Article] Cyclic analogue of S-benzylisothiourea that suppresses kynurenine production without inhibiting indoleamine 2,3-dioxygenase activity.2018
- Author(s)
  Fukuda, M.; Sasaki, T.; Hashimoto, T.; Miyachi, H.; Waki, M.; Asai, A.; Takikawa, O.; Ohno, O.; Matsuno, K.
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 28 Pages: 2846-2849
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08371
[Journal Article] Design and synthesis of a series of a-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved a queous solubility.2013
- Author(s)
  Masao Ohashi, et.al.
- Journal Title
  
  Bioorg. Med Chem.
  
  Volume: 21 Issue: 8 Pages: 2319-2332
- DOI
  10.1016/j.bmc.2013.02.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07435, KAKENHI-PROJECT-23247016, KAKENHI-PROJECT-23390329, KAKENHI-PROJECT-23590128, KAKENHI-PROJECT-24370046
[Journal Article] Structure-guided design, synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands.2013
- Author(s)
  Beniyama Y, Matsuno K, Miyachi H.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 23 Issue: 6 Pages: 1662-1666
- DOI
  10.1016/j.bmcl.2013.01.054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590128
[Journal Article] Peroxisome Proliferator-Activated Receptor delta Antagonists Inhibit Hepatitis C Virus RNA Replication2013
- Author(s)
  Ban S, Ueda Y, Ohashi M, Matsuno K, Ikeda M, Kato N, Miyachi H
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 23(17) Pages: 4774-4778
- Data Source
  KAKENHI-PROJECT-23590128
[Journal Article] Design and synthesis of a series ofα-benzyl phenylpropanoic acid-type peroxisome proliferator-activated receptor (PPAR) gamma partial agonists with improved aqueous solubility2013
- Author(s)
  Ohashi M, Oyama T, Putranto EW, Waku T, Nobusada H, Kataoka K, Matsuno K, Yashiro M, Morikawa K, Huh NH, Miyachi H
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 21(8) Pages: 2319-2332
- Data Source
  KAKENHI-PROJECT-23590128
[Journal Article] Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replication.2013
- Author(s)
  Ban S, Ueda Y, Ohashi M, Matsuno K, Ikeda M, Kato N, Miyachi H.
- Journal Title
  
  Bioorg Med Chem Lett.
  
  Volume: 23 Issue: 17 Pages: 4774-4778
- DOI
  10.1016/j.bmcl.2013.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590128
[Journal Article] Structure-guideddesign,synthesis and in vitro evaluation of a series of pyrazole-based fatty acid binding protein (FABP) 3 ligands2013
- Author(s)
  Beniyama Y, Matsuno K, Miyachi H
- Journal Title
  
  Bioorg. Med. Chem. Lett
  
  Volume: 3 Pages: 1662-1666
- Data Source
  KAKENHI-PROJECT-23590128
[Journal Article] Design, synthesis and in vitro evaluation of a series of a-substituted phenylpropanoic acid PPARy agonists to further investigate the stereochemistry-activity relationship2012
- Author(s)
  Masao Ohashi, et.al.
- Journal Title
  
  Bioorg. Med Chem.
  
  Volume: 20 Issue: 21 Pages: 6375-6383
- DOI
  10.1016/j.bmc.2012.08.061
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07435, KAKENHI-PROJECT-22249006, KAKENHI-PROJECT-23590128
[Journal Article] Design, synthesis and in vitro evaluation of a series ofα-substituted phenylpropanoic acid PPARγagonists to further investigate the stereochemistry-activity relationship2012
- Author(s)
  Ohashi M, Nakagome I, Kasuga J, Nobusada H, Matsuno K, Makishima M, Hirono S, Hashimoto Y, Miyachi H
- Journal Title
  
  Bioorg. Med. Chem
  
  Volume: 20 Pages: 375-383
- Data Source
  KAKENHI-PROJECT-23590128
[Patent] 環状ペプチド化合物，キヌレニン産生阻害剤及び医薬組成物2020
- Inventor(s)
  大野修，松野研司
- Industrial Property Rights Holder
  学校法人工学院大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-140431
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-18K05341
[Patent] 環状ペプチド化合物、キヌレニン産生阻害剤及び医薬組成物2019
- Inventor(s)
  大野修、松野研司
- Industrial Property Rights Holder
  大野修、松野研司
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] センナリヅタ由来のkynurenine産生阻害剤caulerpinの単離および機能解析2024
- Author(s)
  上野航太郎、小岩井優、坂田優希、照屋俊明、松野研司、大野修
- Organizer
  日本化学会第104春季年会（船橋）
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] 核内受容体RORγt活性とkynurenine産生機構の相関の解析2024
- Author(s)
  長谷部友花、里中彗伊太、武田翔太、大野修、松野研司
- Organizer
  日本化学会第104春季年会（船橋）
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] センナリヅタ由来のkynurenine産生阻害剤caulerpinの単離と機能解析2023
- Author(s)
  上野航太郎、小岩井優、坂田優希、照屋俊明、松野研司、大野修
- Organizer
  第13回 CSJ化学フェスタ2023（東京）
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] スズメバチ由来新規キチナーゼ阻害剤の単離、合成と機能解明2023
- Author(s)
  笠原駿輔、権来悟、萩原佳輔、木村将大、加藤学、景山心悟、生田智樹、松野研司、大野修
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] LSD1/LSD2阻害活性を有する2-phenylcyclopropylamine誘導体の合成研究2023
- Author(s)
  塩原彩音、小林明日香、田房崚、深澤隼介、橋本知子、大野修、丹羽英明、佐藤心、梅原崇史、垂水小百合、松野研司
- Organizer
  日本薬学会　第143回年会
- Data Source
  KAKENHI-PROJECT-21K06461
[Presentation] センナリヅタ由来の kynurenine 産生阻害阻害剤 caulerpin の単離と機能解析2023
- Author(s)
  上野航太郎、坂田優希、照屋俊明、松野研司、大野修
- Organizer
  第10回工学院大学先進工学部イノベーションフォーラム［Innovation Forum of Advanced Engineering and Education(IFAEE)］（八王子）
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] スズメバチに含まれる新規生物活性物質の単離と機能解析2023
- Author(s)
  権来悟、萩原佳輔、笠原駿輔、木村将大、加藤学、景山心悟、生田智樹、松野研司、大野修
- Organizer
  第67回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] 栄養飢餓選択的細胞死誘導物質panaxcerol Bの単離、合成と生物活性2023
- Author(s)
  金窪爽音、長屋裕貴、松野研司、大野修
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] キヌレニン産生を抑制する環状デプシペプチドKNP-1の構造決定および全合成研究2023
- Author(s)
  古内志拓、人見悠毅、佐々木智未、岡本岳大、辻厳一郎、黒原崇、出水庸介、大野修、松野研司
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] Kynurenine産生機構における核内受容体RORγtの寄与2023
- Author(s)
  長谷部友花、里中彗伊太、武田翔太、大野修、松野研司
- Organizer
  第13回 CSJ化学フェスタ2023（東京）
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] 軟体サンゴ由来プロスタグランジンA2（PGA2）によるリポポリサッカライドのシグナル伝達阻害活性2023
- Author(s)
  保科智之、水野瑛夏、宮本順一郎、松野研司、大野修
- Organizer
  日本化学会第103春季年会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] オオスズメバチに含まれるキチナーゼ阻害剤の探索と機能解析2022
- Author(s)
  権来悟、萩原佳輔、笠原駿輔、木村将大、小山文隆、加藤学、景山心悟、生田智樹、松野研司、大野修
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] Kynurenine産生を抑制する環状デプシペプチドKNP-1の構造決定および全合成研究2022
- Author(s)
  古内志拓、人見悠毅、佐々木智未、岡本岳大、辻厳一郎、黒原崇、出水庸介、大野修、松野研司
- Organizer
  第39回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] 2-Phenylcyclopropylamine（PCPA）誘導体の立体配置とLSD1阻害活性の構造活性相関2022
- Author(s)
  塩原彩音、田房崚、深澤隼介、橋本知子、橋本隼、大野修、丹羽英明、佐藤心、梅原崇史、松野研司
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K06461
[Presentation] オオスズメバチ代謝物質に含まれる新規生物活性物質の探索と機能解析2022
- Author(s)
  権来悟、萩原佳輔、廣瀬琴美、木村将大、小山文隆、加藤学、景山心悟、生田智樹、松野研司、大野修
- Organizer
  第66回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] 2-Phenylcyclopropylamine（PCPA）誘導体の立体配置とLSD1阻害活性の構造活性相関2022
- Author(s)
  塩原彩音、田房崚、深澤隼介、橋本知子、橋本隼、大野修、丹羽英明、佐藤心、梅原崇史、松野研司
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-21K06461
[Presentation] 海洋シアノバクテリア由来新規キヌレニン産生阻害物質の単離と機能解明2022
- Author(s)
  大野修、松野研司
- Organizer
  第34回海洋生物活性談話会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] RORγt agonistによるキヌレニン産生阻害作用の解析2022
- Author(s)
  里中彗伊太、武田翔太、大野修、松野研司
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] LSD2阻害剤の合成研究2022
- Author(s)
  塩原彩音、深澤隼介、橋本知子、田房崚、大野修、丹羽英明、佐藤心、梅原崇史、松野研司
- Organizer
  第39回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-21K06461
[Presentation] 海洋生物に由来する栄養飢餓選択的な細胞死誘導物質の単離と機能解析2022
- Author(s)
  相田恵理香、岩崎有紘、末永聖武、松野研司、大野修
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] プロスタグランジンA2（PGA2）によるリポポリサッカライドのシグナル伝達阻害活性の解析2022
- Author(s)
  水野瑛夏、宮本順一郎、松野研司、大野修
- Organizer
  日本化学会第102春季年会
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] キイロスズメバチ由来キチナーゼ阻害物質の単離と機能解析2021
- Author(s)
  萩原佳輔、木村将大、小山文隆、加藤学、景山心悟、生田智樹、松野研司、大野修
- Organizer
  第65回日本応用動物昆虫学会大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] キヌレニン産生抑制剤の探索2021
- Author(s)
  武田翔太、水本友紀子、安達優輝、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] リシン脱メチル化酵素LSD1およびLSD2に対するシスおよびトランス-2-フェニルシクロプロピルアミン由来阻害剤の構造を基にした開発と評価2021
- Author(s)
  丹羽英明、田房峻、渡邉千鶴、佐藤心、原田俊之、渡辺寿美、深澤駿介、橋本知子、中村香奈、田仲昭子、白水美香子、本間光貴、松野研司、梅原崇史
- Organizer
  第44回分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06461
[Presentation] 沖縄県産ソフトコーラルに由来するリポポリサッカライド機能阻害剤の単離2021
- Author(s)
  宮本順一郎、佐野拓哉、松野研司、大野修
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] Indoleamine 2,3-dioxygenase 1阻害活性を有するcarbono(di)thioate誘導体の発見2021
- Author(s)
  熊澤美幸、手嶋真武、外山詩織、福田美和、武田翔太、宮地弘幸、浅井章良、滝川修、橋本知子、大野修、松野研司
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] キヌレニン産生抑制剤の探索2021
- Author(s)
  武田翔太、水本友紀子、安達優輝、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] キイロスズメバチ由来キチナーゼ阻害物質の単離と機能解析2021
- Author(s)
  大野修、萩原佳輔、木村将大、権来悟、小山文隆、加藤学、景山心悟、生田智樹、松野研司
- Organizer
  第67回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-21K05295
[Presentation] 海洋生物由来lipopolysaccharide機能阻害剤の探索研究2020
- Author(s)
  佐野拓哉、人見悠毅、宮本順一郎、松野研司、大野修
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋シアノバクテリア由来新規キヌレニン産生阻害剤の構造解析および生物活性2020
- Author(s)
  人見悠毅、佐々木智未、中風奈々恵、浅井章良、滝川修、大野修、松野研司
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋シアノバクテリア由来新規キヌレニン産生阻害剤の構造解析および生物活性2020
- Author(s)
  大野修、佐々木智未、人見悠毅、中風奈々恵、浅井章良、滝川修、松野研司
- Organizer
  第62回天然有機化合物討論会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 沖縄県産ウミキノコからのlipopolysaccharide機能阻害物質の単離2019
- Author(s)
  宮本順一郎、佐野拓哉、松野研司、大野修
- Organizer
  第63回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物からの栄養飢餓選択的な細胞死誘導物質の探索2019
- Author(s)
  長屋裕貴、山田亮一、向畑壱成、松野研司、大野修
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物からの栄養飢餓選択的な細胞死誘導物質の探索2019
- Author(s)
  長屋裕貴、向畑壱成、松野研司、大野修
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋シアノバクテリア由来新規キヌレニン産生阻害剤の構造解析および生物活性2019
- Author(s)
  人見悠毅、佐々木智未、中風奈々恵、浅井章良、滝川修、大野修、松野研司
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物由来新規lipopolysaccharide機能阻害剤の探索2019
- Author(s)
  佐野拓哉、人見悠毅、寺崎拓郎、岩崎有紘、末永聖武、松野研司、大野修
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] キヌレニン産生抑制剤の探索2019
- Author(s)
  武田翔太、鈴木健二、水本友紀子、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  第63回日本薬学会関東支部大会（東京）
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] 海洋生物由来新規lipopolysaccharide機能阻害剤の探索2019
- Author(s)
  佐野拓哉、人見悠毅、寺崎拓郎、松野研司、大野修
- Organizer
  第63回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] キヌレニン産生抑制剤の探索2019
- Author(s)
  武田翔太、鈴木健二、水本友紀子、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  第63回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] シアノバクテリア由来新規キヌレニン産生阻害剤の構造解析2019
- Author(s)
  人見悠毅、佐々木智未、中風奈々恵、浅井章良、滝川修、大野修、松野研司
- Organizer
  第63回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] チューブリン結合性キナゾリン化合物の細胞周期M期阻害活性の解析2019
- Author(s)
  澤田潤一、石井浩介、鈴木由美子、松野研司、浅井章良
- Organizer
  日本薬学会第139年会（千葉）
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] キヌレニン産生抑制剤の探索2019
- Author(s)
  武田翔太、鈴木健二、水本友紀子、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  第37回メディシナルケミストリーシンポジウム（八王子）
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] 化合物ライブラリーからのキヌレニン産生抑制剤の探索2019
- Author(s)
  武田翔太、鈴木健二、水本友紀子、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  新規素材探索研究会第18回セミナー
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 化合物ライブラリーからのキヌレニン産生抑制剤の探索2019
- Author(s)
  武田翔太、鈴木健二、水本友紀子、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  新規素材探索研究会探索研究会第18回セミナー（横浜）
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] 海洋生物由来小胞体ストレス誘導性アポトーシス阻害剤の探索2019
- Author(s)
  佐藤慶吾、本間椋、松野研司、大野修
- Organizer
  日本化学会第99春季年会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] キヌレニン産生抑制剤の探索2019
- Author(s)
  武田翔太、鈴木健二、水本友紀子、浅井章良、滝川修、齋藤隆夫、大野修、松野研司
- Organizer
  第37回メディシナルケミストリーシンポジウム
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] Synthtic studies on GPR35 agonist without species-specificity2019
- Author(s)
  Koide, T.; Watanabe, T.; Naganuma, M. Hashimoto, T.; Akaki, S.; Furuta, K.; Yamamoto, Y.; Nagashima, S.; Tokiwa, H.; Tanaka, S.; Ohno, O.; Matsuno, K.
- Organizer
  27th International Society of Heterocyclic Chemistry Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] IDO阻害剤の合成研究：イソチオウレア構造の変換によるキヌレニン産生阻害剤の発見と作用機序解明2019
- Author(s)
  福田美和、佐々木智未、中山寛太、橋本知子、宮地弘幸、脇稔、浅井章良、滝川修、大野修、松野研司
- Organizer
  第37回メディシナルケミストリーシンポジウム（八王子）
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] Elucidation of the mechanism of action for benzimidazole analogues as potent kynurenine production inhibitor.2019
- Author(s)
  Fukuda, M.; Sasaki, T.; Hashimoto, T.; Miyachi, H.; Waki,M. ;Asai, A.; Takikawa, O.; Ohno, O.; Matsuno, K.
- Organizer
  EFMC-ACSMEDI MedChem Frontiers 201
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08371
[Presentation] 海洋生物由来小胞体ストレス誘導性細胞死阻害剤の探索2018
- Author(s)
  佐藤慶吾、本間椋、松野研司、大野修
- Organizer
  新規素材探索研究会第17回セミナー
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物由来リポポリサッカライド（LPS）機能調節物質の探索2018
- Author(s)
  人見悠毅、寺崎拓郎、岩崎有紘、末永聖武、松野研司、大野修
- Organizer
  新規素材探索研究会第17回セミナー
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物由来LPS誘導性NO産生阻害物質の探索2018
- Author(s)
  佐野拓哉、寺崎拓郎、岩崎有紘、末永聖武、松野研司、大野修
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物由来新規キヌレニン産生抑制物質の探索2018
- Author(s)
  大野修、佐々木智未、浅井章良、滝川修、松野研司
- Organizer
  第65回トキシンシンポジウム
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] Isolation and Functional Analysis of Novel Compounds with Selective Cytotoxicity under Glucose-restricted Conditions2018
- Author(s)
  Osamu Ohno, Yuki Nagaya, Ami Ito, Arihiro Iwasaki, Kiyotake Suenaga, Kenji Matsuno
- Organizer
  ICPAC Langkawi 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] 海洋生物由来の小胞体ストレス誘導性細胞死阻害剤の探索2018
- Author(s)
  佐藤慶吾、本間椋、松野研司、大野修
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-18K05341
[Presentation] BENZIMIDAZOLE ANALOGUES AS KYNURENINE PRODUCTION INHIBITOR WITHOUT INDOLEAMINE 2,3-DIOXYGENASE INHIBITION2016
- Author(s)
  Fukuda, M.; Suzuki, K.; Sasaki, T.; Miyachi, H.; Waki, M.; Asai, A.; Hashimoto, T.; Ohno, O.; Takikawa, O.; Matsuno, K.
- Organizer
  XXIV EFMC International Symposium on Medicinal Chemistry
- Place of Presentation
  Manchester, UK
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460149
[Presentation] Cyclisation of Benzylisothiourea Provided Kynurenine Production Inhibitor without Indoleamine 2,3-Dioxygenase Inhibition.2015
- Author(s)
  Fukuda, M.; Miyachi, H.; Waki, M.; Asai, A.; Takikawa, O.; Matsuno, K.
- Organizer
  EFMC-ASMC'15 6th EFMC International Symposium on Advances in Synthetic and Medicinal Chemistry
- Place of Presentation
  Rehovot, Israel
- Year and Date
  2015-11-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460149
[Presentation] Benzimidazole 構造を有する新規indoleamine 2,3-dioxygenase (IDO) 阻害剤の合成と
- Author(s)
  福田美和、脇稔、浅井章良、滝川修、宮地弘幸、松野研司
- Organizer
  第31回メディシナルケミストリーシンポジウム
- Place of Presentation
  広島市
- Data Source
  KAKENHI-PROJECT-25460149
[Presentation] Indoleamine 2,3-dioxygenase (IDO) 阻害活性を有するbenzimidazole系化合物の創製
- Author(s)
  福田美和、脇稔、浅井章良、滝川修、宮地弘幸、松野研司
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本市
- Data Source
  KAKENHI-PROJECT-25460149

1. Ohno Osamu (20436992)

# of Collaborated Projects: 4 results

# of Collaborated Products: 60 results
2. Kawataki Tomoyuki (20303406)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. HIROYUKI MIYACHI (20376643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
4. 梅原崇史 (20415095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. 赤木玲子 (50150967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小田康祐 (60571255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 益谷美都子 (60238904)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 出水庸介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MATSUNO Kenji 松野 研司

Research Projects

Research Products

Co-Researchers

Inhibitors of kynurenine production: drug development of non-conventional IDO1 inhibitor A and elucidation of mechanism of action by cpd B.Principal Investigator

Principal Investigator

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海洋生物由来新規キヌレニン産生阻害剤のがん免疫寛容抑制剤としての展開

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LSD阻害剤の創製：LSD1阻害剤の創薬展開およびLSD2機能解明の基盤構築Principal Investigator

Principal Investigator

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Novel combination immunotherapy for glioma with new Tryptophan metabolizing enzyme inhibitor and Interferon

Principal Investigator

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Research Institution

Search for marine organisms-derived compounds that regulate the reprogramming mechanism of cancer cells

Principal Investigator

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Research Institution

Drug development of novel anti-mitotic agent with unique phenotype and elucidation of the mechanism of actionPrincipal Investigator

Principal Investigator

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Research Institution

Research on IDO inhibitor as anticancer agentPrincipal Investigator

Principal Investigator

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Explolation of gamma-secretase modulator based on metabolic nuclear receptor

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[Journal Article] Structure-activity relationship and in silico evaluation of cis- and trans-PCPA-derived inhibitors of LSD1 and LSD2.2022

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DOI

Data Source

[Journal Article] Inhibition of lipopolysaccharide-induced inflammatory signaling by soft-coral-derived prostaglandin A2 in RAW264.7 cells2022

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DOI

Data Source

[Journal Article] Isolation of caldorazole, a thiazole-containing polyketide with selective cytotoxicity under glucose-restricted conditions2022

Author(s)

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DOI

Data Source

[Journal Article] Anti-apoptotic activity of methyl (3R,4E,6Z,15E)-3-hydroxyoctadecatrienoate in human cervical carcinoma HeLa cells2021

Author(s)

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DOI

Data Source

[Journal Article] Discovery of Carbono(di)thioates as Indoleamine 2,3-Dioxygenase 1 Inhibitors.2021

Author(s)

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DOI

Data Source

[Journal Article] Inhibitory effects of biseokeaniamide A against lipopolysaccharide-induced signal transduction2020

Author(s)

Journal Title

MATSUNO Kenji 松野研司