Yasui Manabu 安井学

… Alternative Names

YASUI Manabu 安井学

安井学ヤスイマナブ

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Researcher Number	50435707
Other IDs
Affiliation (Current)	2025: 国立医薬品食品衛生研究所, ゲノム安全科学部, 室長
Affiliation (based on the past Project Information) *help	2023: 国立医薬品食品衛生研究所, ゲノム安全科学部, 室長 2017 – 2022: 国立医薬品食品衛生研究所, 変異遺伝部, 室長 2015 – 2016: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究官 2014: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究員 2011 – 2013: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究官 … More 2012: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究員 2010 – 2011: 国立医薬品食品衛生研究所, 主任研究官 2010: 国立医薬品食品衛生研究所, 変異遺伝部, 主任研究員 2008: National Institute of Health Sciences, 変異遺伝部, 研究員 2007 – 2008: National Institute of Health Sciences, 研究員 2003: 京都大学, 地球環境学堂, 特別研究員(PD) 2002: 京都大学, 工学研究科, 特別研究員(DC2) Less
Review Section/Research Field	Principal Investigator Risk sciences of radiation/Chemicals / Civil and environmental engineering / Basic Section 63030:Chemical substance influence on environment-related / Risk sciences of radiation and chemicals Except Principal Investigator Medium-sized Section 63:Environmental analyses and evaluation and related fields / Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator DNA付加体 / DNA損傷 / 遺伝毒性 / 遺伝子変異 / 環境 / トキシコロジー / バイオマーカー / ^<32>P-ポストラベル法 / 塩基置換 / MS … More / LC / 突然変異 / ホルムアルデヒド / in vitro / 薬物代謝 / 変異原性物質 / S9 / 薬物代謝酵素 / 代謝活性化 / ゲノム / 遺伝子ターゲティング / 遺伝学 / 遺伝子座特異的 / 遺伝子破壊 / １分子 / 二本鎖切断 / ターゲティング / 遺伝毒性発がん物質 / 放射線 / 閾値 / DNA 付加体 / tk遺伝子 / 炎症 / チミジンキナーゼ遺伝子 / 炎症性発癌 / 化学発癌 / 突然変異誘発 / 一酸化窒素 / 活性酸素 / 8-オキソグアニン / 付加体 / 損傷 / DNA … More Except Principal Investigator 放射線影響 / 基質特異性 / 損傷DNA / 水和層 / 水和水 / 量子ダイナミクス / 体温 / B型DNA / 損傷 / ＤＮＡ / 分子認識 / 量子化学計算 / 遺伝子損傷 / 塩基配列 / DNA / 8-オキソグアニン / 水 / 抗がん治療薬 / QSAR / ケモインフォマティクス / TK6細胞 / 変異原 / 発がん物質 / 遺伝毒物学 / 人体有害物質 / トキシコロジー / DNA損傷 / 突然変異 / DNAポリメラーゼζ / トランスリージョンDNA合成 / 遺伝毒性発がん物質 / 閾値 Less

透析膜を利用した新しい代謝活性化システムによるDNA付加体の形成と同定Principal Investigator
- Principal Investigator
  
  安井学
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Health Sciences
Quantum chemical challenge to elucidate the functional mechanism of base sequence specificity deciding removal of the DNA damage
- Principal Investigator
  
  Suzuki Ai
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Tohoku University
Establishment of Novel Bioassays for in vivo Genotoxicity Prediction and Mechanism Characterization
- Principal Investigator
  
  Takeda Shunichi
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyoto University
Site-specific gene mutagenesis involving a single DNA adduct in vivoPrincipal Investigator
- Principal Investigator
  
  Manabu Yasui
- Project Period (FY)
  2013 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  National Institute of Health Sciences
Studies on mechanisms underlying genotoxic thresholds through genetic modification of DNA polymerase zeta
- Principal Investigator
  
  NOHMI Takehiko
- Project Period (FY)
  2010 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
Development of a single DNA adduct-caused gene mutation assay as a model of low-dose exposurePrincipal Investigator
- Principal Investigator
  
  YASUI Manabu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
Mutation mechanism of a single DNA adduct embedded in human genomeof TK6 cellsPrincipal Investigator
- Principal Investigator
  
  YASUI Manabu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  National Institute of Health Sciences
ホルムアルデヒドによって誘発されるDNA付加体の定量法の開発Principal Investigator
- Principal Investigator
  
  安井学
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Civil and environmental engineering
- Research Institution
  Kyoto University

[Journal Article] FTO regulates the DNA damage response via effects on cell-cycle progression2023
- Author(s)
  Liu Weiying、Yasui Manabu、Sassa Akira、You Xinyue、Wan Jingjing、Cao Yiyi、Xi Jing、Zhang Xinyu、Honma Masamitsu、Luan Yang
- Journal Title
  
  Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  
  Volume: 887 Pages: 503608-503608
- DOI
  10.1016/j.mrgentox.2023.503608
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K12263, KAKENHI-PROJECT-19K12339, KAKENHI-PROJECT-23K25002
[Journal Article] Potent mutagenicity of an azide, 3-azido-1,2-propanediol, in human TK6 cells2022
- Author(s)
  Gruz Petr、Yasui Manabu、Ukai Akiko、Horibata Katsuyoshi、Honma Masamitsu、Sugiyama Kei-ichi
- Journal Title
  
  Mutation Research/Genetic Toxicology and Environmental Mutagenesis
  
  Volume: 876-877 Pages: 503475-503475
- DOI
  10.1016/j.mrgentox.2022.503475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K12263
[Journal Article] Follow-up genotoxicity assessment of Ames-positive/equivocal chemicals using the improved thymidine kinase gene mutation assay in DNA repair-deficient human TK6 cells2021
- Author(s)
  A. Sassa, T. Fukuda, A. Ukai, M. Nakamura, R. Sato, S. Fujiwara, K. Hirota, S. Takeda, K.I. Sugiyama, M. Honma, M. Yasui
- Journal Title
  
  Mutagenesis
  
  Volume: 36 Issue: 5 Pages: 331-338
- DOI
  10.1093/mutage/geab025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04337, KAKENHI-PROJECT-19K12339, KAKENHI-PROJECT-21K12263, KAKENHI-PROJECT-21K19235, KAKENHI-PROJECT-19KK0210
[Journal Article] Dynamics of Water Molecules around the DNA Lesions2021
- Author(s)
  Ai Suzuki, Masayuki Miyano, Ryuji Miura, Manabu Yasui
- Journal Title
  
  Proceeding of the 18th International Conference on Flow Dynamics (ICFD2021)
  
  Volume: 1 Pages: 440-441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22903
[Journal Article] Potential Analysis of the Hydration Layer around the Injured DNA2020
- Author(s)
  Ai Suzuki, Masayuki Miyano, Ryuji Miura, Manabu Yasui
- Journal Title
  
  Proceedings of Seventeenth International Conference on Flow Dynamics
  
  Volume: 1 Pages: 328-329
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22903
[Journal Article] Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells.2020
- Author(s)
  Ibrahim MA, Yasui M, Saha LK, Sasanuma H, Honma M, Takeda S
- Journal Title
  
  Environ Mol Mutagen.
  
  Volume: in press Issue: 6 Pages: 602-610
- DOI
  10.1002/em.22371
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-19H04267
[Journal Article] Tyrosyl-DNA phosphodiesterases are involved in mutagenic events at a ribonucleotide embedded into DNA in human cells2020
- Author(s)
  Takeishi Ayuna、Kogashi Hiroyuki、Odagiri Mizuki、Sasanuma Hiroyuki、Takeda Shunichi、Yasui Manabu、Honma Masamitsu、Suzuki Tetsuya、Kamiya Hiroyuki、Sugasawa Kaoru、Ura Kiyoe、Sassa Akira
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 12 Pages: 0244790-0244790
- DOI
  10.1371/journal.pone.0244790
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12339, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-19H04267, KAKENHI-PROJECT-19K22561
[Journal Article] Current perspectives on mechanisms of ribonucleotide incorporation and processing in mammalian DNA2019
- Author(s)
  Sassa Akira、Yasui Manabu、Honma Masamitsu
- Journal Title
  
  Genes and Environment
  
  Volume: 41 Issue: 1 Pages: 3-3
- DOI
  10.1186/s41021-019-0118-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K16195, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-25281022
[Journal Article] Comparative study of cytotoxic effects induced by environmental genotoxins using XPC- and CSB-deficient human lymphoblastoid TK6 cells2019
- Author(s)
  Sassa Akira、Fukuda Takayuki、Ukai Akiko、Nakamura Maki、Takabe Michihito、Takamura-Enya Takeji、Honma Masamitsu、Yasui Manabu
- Journal Title
  
  Genes and Environment
  
  Volume: 41 Issue: 1 Pages: 15-15
- DOI
  10.1186/s41021-019-0130-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12339, KAKENHI-PROJECT-19K12344, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-16K16195
[Journal Article] ALC1/CHD1L, a chromatin-remodeling enzyme, is required for efficient base excision repair.2017
- Author(s)
  Tsuda M, Cho K, Ooka M, Shimizu N, Watanabe R, Yasui A, Nakazawa Y, Ogi T, Harada H, Agama K, Nakamura J, Asada R, Fujiike H, Sakuma T, Yamamoto T, Murai J, Hiraoka M, Koike K, Pommier Y, Takeda S, Hirota K.
- Journal Title
  
  PLos One
  
  Volume: 12 Issue: 11 Pages: e0188320-e0188320
- DOI
  10.1371/journal.pone.0188320
- NAID
  120006800808
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05333, KAKENHI-PUBLICLY-16H01314, KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-15H01737, KAKENHI-PROJECT-17H00783, KAKENHI-PROJECT-16H02957, KAKENHI-PROJECT-16J02252, KAKENHI-PROJECT-16K12598, KAKENHI-PROJECT-16K18478, KAKENHI-PROJECT-17H01877
[Journal Article] Mutagenic consequences of cytosine alterations site-specifically embedded in the human genome.2016
- Author(s)
  Sassa A, Kanemaru Y, Kamoshita N, Honma M, Yasui M.
- Journal Title
  
  Genes and Environment
  
  Volume: 38 Issue: 1 Pages: 17-17
- DOI
  10.1186/s41021-016-0045-9
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-16K16195
[Journal Article] Mutator phenotype and DNA double-strand break repair in BLM helicase-deficient human cells.2016
- Author(s)
  Suzuki T, Yasui M, Honma M
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 36 Issue: 23 Pages: 2877-2889
- DOI
  10.1128/mcb.00443-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-25340044
[Journal Article] Impact of Ribonucleotide Backbone on Translesion Synthesis and Repair of 7,8-Dihydro-8-oxoguanine.2016
- Author(s)
  Sassa A, Caglayan M, Rodriguez Y, Beard WA, Wilson SH, Nohmi T, Honma M, Yasui M
- Journal Title
  
  J Biol Chem.
  
  Volume: 291 Issue: 46 Pages: 24314-24323
- DOI
  10.1074/jbc.m116.738732
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306, KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-16K16195
[Journal Article] Xeroderma Pigmentosum Group A Suppresses Mutagenesis Caused by Clustered Oxidative DNA Adducts in the Human Genome2015
- Author(s)
  Sassa A, Kamoshita N, Kanemaru Y, Honma M, Yasui M
- Journal Title
  
  PLOS ONE
  
  Volume: 10 Issue: 11 Pages: e0142218-e0142218
- DOI
  10.1371/journal.pone.0142218
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25340044, KAKENHI-PROJECT-25281022
[Journal Article] Mechanism of induction of binucleated cells by multiwalled carbon nanotubes as revealed by live-cell imaging analysis.2015
- Author(s)
  Yasui M, Kamoshita N, Nishimura T, Honma M
- Journal Title
  
  Genes and Environment
  
  Volume: 37
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25281022
[Journal Article] Tracing the fates of site-specifically introduced DNA adducts in the human genome.2014
- Author(s)
  Yasui M, Kanemaru Y, Kamoshita N, Suzuki T, Arakawa T, and Honma M.
- Journal Title
  
  DNA Repair
  
  Volume: 15 Pages: 11-20
- DOI
  10.1016/j.dnarep.2014.01.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044
[Journal Article] in vivo evidence that phenylalanine 171 acts as a molecular brake for translesion DNA synthesis across benzo[a]pyrene DNA adducts by human DNA polymerase2014
- Author(s)
  A. Sassa, T. Suzuki, Y. Kanemaru, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R.C. Gupta, F. Johnson, T. Ohta, M. Honma, N. Adachi and T. Nohmi
- Journal Title
  
  DNA Repair
  
  Volume: 15 Pages: 21-28
- DOI
  10.1016/j.dnarep.2013.12.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-24659035, KAKENHI-PROJECT-25281022, KAKENHI-PROJECT-25340044
[Journal Article] Miscoding properties of 8-chloro-2'-deoxyguanosine, a hypochlorous acid-induced DNA adduct,catalysed by human DNA polymerases2013
- Author(s)
  Sassa A, Kamoshita N, Matsuda T, Ishii Y,Kuraoka I, Nohmi T, Ohta T, Honma M, and Yasui M
- Journal Title
  
  Mutagenesis
  
  Volume: 28 Pages: 81-88
- Data Source
  KAKENHI-PROJECT-22710068
[Journal Article] Miscoding properties of 8-chloro-2'-deoxyguanosine, a hypochlorous acid-induced DNA adduct, catalysed by human DNA polymerases2013
- Author(s)
  A. Sassa
- Journal Title
  
  Mutagenesis
  
  Volume: 28 Issue: 1 Pages: 81-88
- DOI
  10.1093/mutage/ges056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-22510075, KAKENHI-PROJECT-22710068, KAKENHI-PROJECT-23221006
[Journal Article] 2nd International Symposium on Genotoxic and Carcinogenic Thresholds2012
- Author(s)
  T. Nohmi, M. Honma, M. Yamada, K. Masumura, M. Yasui, K. Horibata and S. Fukushima
- Journal Title
  
  Genes and Environment
  
  Volume: 34 Issue: 4 Pages: 141-145
- DOI
  10.3123/jemsge.34.141
- NAID
  10031125861
- ISSN
  1880-7046, 1880-7062
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016
[Journal Article] Mutational specificities of brominated DNA adducts catalyzed by human DNA polymerases.2011
- Author(s)
  Akira Sassa (Corresponding author ; Manabu Yasui)
- Journal Title
  
  Journal of Molecular Biology
  
  Volume: 406 Pages: 679-686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710068
[Journal Article] Phenylalanine 171 is a molecular brake for translesion synthesis across benzo[a]pyrene-guanine adducts by human DNA polymerase kappa2011
- Author(s)
  A. Sassa, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R. C. Gupta, F. Johnson, T. Ohta and T. Nohmi
- Journal Title
  
  Mutat. Res.
  
  Volume: 718 Issue: 1-2 Pages: 10-17
- DOI
  10.1016/j.mrgentox.2010.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-22710068
[Journal Article] Induction of TK mutations in human lymphoblastoid TK6 cells by the rat carcinogen 3-chloro-4-(dichloromethyl)-5-hydro xy-2(5H)-furanone (MX)2011
- Author(s)
  Hakulinen P, Yamamoto A, Koyama N, Kumita W, Yasui M, and Honma M
- Journal Title
  
  Mutation Res
  
  Volume: 725 Issue: 1-2 Pages: 43-49
- DOI
  10.1016/j.mrgentox.2011.07.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710068
[Journal Article] Acrylamide genotoxicity in young versus adult gpt delta male rats2011
- Author(s)
  N. Koyama
- Journal Title
  
  Mutagenesis
  
  Volume: 26 Issue: 4 Pages: 545-549
- DOI
  10.1093/mutage/ger014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-22710068
[Journal Article] Mutational specificities of brominated DNA adducts catalyzed by human DNA polymerases2011
- Author(s)
  A. Sassa
- Journal Title
  
  J.Mol.Biol
  
  Volume: 406 Issue: 5 Pages: 679-686
- DOI
  10.1016/j.jmb.2011.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22241016, KAKENHI-PROJECT-22710068
[Journal Article] Live cell imaging of micronucleus formation and development2010
- Author(s)
  Yasui M, Koyama N, Koizumi T, Senda-Murata K, Takashima Y, Hayashi M, Sugimoto K, and Honma M
- Journal Title
  
  Mutation Res.
  
  Volume: 692 Issue: 1-2 Pages: 12-18
- DOI
  10.1016/j.mrfmmm.2010.07.009
- Data Source
  KAKENHI-PROJECT-22710068
[Journal Article] Live cell imaging of micronucleus formation and development.2010
- Author(s)
  Manabu Yasui
- Journal Title
  
  Mutation Research
  
  Volume: 692 Pages: 12-18
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22710068
[Journal Article] Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases2008
- Author(s)
  Yasui, M., Suenaga, E., Koyama, N., Masutani, C., Hanaoka, F., Gruz, P., Shibutani, S., Nohmi, T.,Hayashi, M., and Honma, M
- Journal Title
  
  Journal of Molecular Biology 377
  
  Pages: 1015-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710059
[Journal Article] Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.2008
- Author(s)
  Manabu Yasui
- Journal Title
  
  Journal of Molecular Biology 377
  
  Pages: 1015-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710059
[Journal Article] Miscoding properties of 2'-deoxyinosine, a nitric oxide-derived DNA Adduct, during translesion synthesis catalyzed by human DNA polymerases.2008
- Author(s)
  Yasui M, Suenaga E, Koyama N, M asutani C, Hanaoka F, Gruz P, Shibutani S, Nohmi T, Hayashi M, and Honma M.
- Journal Title
  
  Journal of Molecular Biology 377
  
  Pages: 1015-1023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710059
[Journal Article] Mechanism of translesion synthesis past an equine estrogen-DNA adduct by Y-family DNA polymerases.2007
- Author(s)
  Mauabu Yasui
- Journal Title
  
  Journal of Molecular Biology 371
  
  Pages: 1151-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710059
[Journal Article] Mechanism of translesion synthesis past an equine estrogen-DNA adduct by Y-family DNA polymerases2007
- Author(s)
  Yasui, M., Suzuki, N., Liu, X., Okamoto, Y., Kim, S.Y., Laxmi, Y.R., and Shibutani, S
- Journal Title
  
  Journal of Molecular Biology 371
  
  Pages: 1151-1162
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] 第Ⅱ相薬物代謝酵素を機能させた補因子補充型in vitro小核試験系の構築2023
- Author(s)
  安井学、鵜飼明子、澁谷眞也、本間正充、杉山圭一
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-21K12263
[Presentation] Data Independent Acquisition法によるトキシコプロテオミクスの統合型in vitro遺伝毒性試験の試みと問題点2022
- Author(s)
  安井学、鵜飼明子、足立淳、鈴木孝昌、本間正充、杉山圭一
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Data Source
  KAKENHI-PROJECT-21K12263
[Presentation] Potent mutagenicity of azidoglycerol in human TK6 cells.2022
- Author(s)
  Gruz P, Yasui M, Ukai A, Horibata K, Honma M, Sugiyama KI
- Organizer
  7th Asian Conference on Environmental Mutagens and the 19th Conference of Chinese Environmental Mutagen Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K12263
[Presentation] MGMT持続発現型TK6細胞を用いた遺伝毒性試験のための基礎的研究2021
- Author(s)
  安井学, 佐々彰, 鵜飼明子, 足立淳, 鈴木孝昌, 本間正充, 杉山圭一
- Organizer
  日本環境変異原ゲノム学会第50回記念大会
- Data Source
  KAKENHI-PROJECT-21K12263
[Presentation] Dynamics of Water Molecules around the DNA Lesions2021
- Author(s)
  Ai Suzuki, Masayuki Miyano, Ryuji Miura, Manabu Yasui
- Organizer
  The 18th International Conference on Flow Dynamics (ICFD2021)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22903
[Presentation] TK6 細胞を用いたin vitro 小核試験結果における MGMT 遺伝子発現の役割2020
- Author(s)
  福田隆之, 鵜飼明子, 西村諒一, 中村真生, 佐々彰, 安井学
- Organizer
  日本環境変異原学会第49回大会
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] Analysis by an Accelerated Quantum Chemical Molecular Dynamics Method for the 8-oxoG added DNA structure2019
- Author(s)
  Ai Suzuki, Akira Sassa, Manabu Yasui, Masamitsu Honma
- Organizer
  The Chem-Bio Informatics Society 情報計算化学生物学会
- Data Source
  KAKENHI-PROJECT-19K22903
[Presentation] 水分子に囲まれた8-オキソグアニン付加DNAと無傷DNAの高速化量子計算を用いた骨格比較解析2019
- Author(s)
  鈴木　愛, 佐々彰, 安井学, 本間正充
- Organizer
  第6回アジア環境変異原学会／日本環境変異原学会第48回大会合同大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22903
[Presentation] Alternate processing pathways of a single ribonucleotide incorporated into DNA and its consequences in human cells.2019
- Author(s)
  Akira SASSA, Haruto TADA, Ayuna TAKEISHI, Kaho HARADA, Kazuma NAKATANI, Masataka TSUDA, Hiroyuki SASANUMA, Shunichi TAKEDA, Kaoru SUGASAWA, Manabu YASUI, Masamitsu HONMA, Kiyoe URA
- Organizer
  The Joint Meeting of The 6th Asian Congress on Environmental Mutagens and The 48th Japanese Environmental Mutagen Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] FTO's roles in DNA damage response and underlying mechanism.2019
- Author(s)
  Weiying LIU, Manabu YASUI, Akira SASSA, Yiyi CAO, Jing XI, Xinyue YOU, Masamitsu HONMA, Yang LUAN
- Organizer
  The Joint Meeting of The 6th Asian Congress on Environmental Mutagens and The 48th Japanese Environmental Mutagen Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] Mechanistic insight of unique mutations caused by a ribonucleotide embedded into DNA.2019
- Author(s)
  Ayuna TAKEISHI, Manabu YASUI, Hiroyuki SASANUMA, Shunichi TAKEDA, Kaoru SUGASAWA, Masamitsu HONMA, Kiyoe URA, Akira SASSA
- Organizer
  The Joint Meeting of The 6th Asian Congress on Environmental Mutagens and The 48th Japanese Environmental Mutagen Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] リボヌクレオチドが誘発する奇異突然変異とその防御機構2018
- Author(s)
  佐々彰, 安井学, 竹石歩奈, 原田佳歩, 鈴木慈, 津田雅貴, 笹沼博之, 武田俊一, 菅澤薫, 本間正充, 浦聖恵
- Organizer
  日本遺伝学会
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA二本鎖切断修復におけるヒストンメチル化酵素NSD2の機能解析2018
- Author(s)
  東條あかり, 佐々彰, 安井学, 本間正充, 浦聖恵
- Organizer
  日本環境変異原学会
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA 中のリボヌクレオチドが引き起こす特異な突然変異とその誘発機構の解析2018
- Author(s)
  竹石歩奈, 安井学, 笹沼博之, 武田俊一, 菅澤薫, 本間正充, 浦聖恵, 佐々彰
- Organizer
  日本環境変異原学会
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Quantum Chemical Inspection on the DNA Backbone Bias caused by 8oxoG2018
- Author(s)
  Suzuki A, Miyano M, Miura R, Sassa A, Yasui M, Honma M
- Organizer
  The International Conference on Flow Dynamics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Trial for establishment of a locus-specific mutation assay system2017
- Author(s)
  Yasui M, Sassa A, Ukai A, Honma M
- Organizer
  12th International Conference of Environmental Mutagens
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] TK6及び変異株を用いたヌクレオチド除去修復機構におけるゲノム全体修復と転写共役修復を区別する方法の開発2017
- Author(s)
  中村真生，鵜飼明子，佐々彰，髙部道仁，福田隆之，髙村岳樹，本間正充，安井学
- Organizer
  日本環境変異原学会第46回大会
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] TK6及びそのDNA修復遺伝子破壊変異体を用いた高感度遺伝毒性試験法の開発2017
- Author(s)
  福田隆之、中村真生、佐藤亮佑、藤原聖、佐々彰、鵜飼明子、武田俊一、安井学、本間正充
- Organizer
  日本環境変異原学会第46回大会
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] TK6及びそのDNA修復遺伝子破壊変異体を用いた高感度遺伝毒性試験法の開発2017
- Author(s)
  福田隆之，中村真生，佐藤亮佑，藤原聖，佐々彰，鵜飼明子，武田俊一，安井学，本間正充
- Organizer
  日本環境変異原学会第46回大会
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Highly sensitive genotoxicity test system for detection of ames-positive compounds in TK6 and its DNA repair mutants2017
- Author(s)
  Fukuda T, Nakamura M, Sato R, Fujiwara S, Sassa A, Ukai A, Takeda S, Yasui M, Honma M
- Organizer
  12th International Conference of Environmental Mutagens
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] TK6及び変異株を用いたヌクレオチド除去修復機構におけるゲノム全体修復と転写共役修復を区別する方法の開発2017
- Author(s)
  中村真生、鵜飼明子、佐々彰、髙部道仁、福田隆之、髙村岳樹、本間正充、安井学
- Organizer
  日本環境変異原学会第46回大会
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] Tracing the fate of site-specifically introduced oxidative dna damage in the human genome2016
- Author(s)
  Honma M, Kanemaru Y, Kamoshita N, Suzuki T, Arakawa T, Sasa A, Yasui M
- Organizer
  14th International Workshop on Radiation Damage to DNA
- Place of Presentation
  メルボルン
- Year and Date
  2016-03-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA中の酸化リボヌクレオチドがDNA複製および修復機構に及ぼす影響2016
- Author(s)
  佐々彰，Caglayan M, Beard WA, Wilson SH, 能美健彦，本間正充，安井学
- Organizer
  第45回日本環境変異原学会
- Place of Presentation
  つくば国際会議場（茨城県・つくば市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16H06306
[Presentation] DNA中の酸化リボヌクレオチドがDNA複製および修復機構に及ぼす影響2016
- Author(s)
  佐々彰，Caglayan M, Beard WA, Wilson SH, 能美健彦，本間正充，安井学
- Organizer
  日本環境変異原学会
- Place of Presentation
  つくば
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] 8-oxoG付加数の異なるDNAに対する修復タンパクhOGG1の高速化量子分子動力学法による親和性評価2016
- Author(s)
  鈴木愛，Bonnaud P，佐々彰，安井学，宮本明，本間正充
- Organizer
  日本環境変異原学会
- Place of Presentation
  つくば
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] ヒトリンパ球細胞のゲノムに導入したシトシン修飾体の潜在的な突然変異誘発能2015
- Author(s)
  佐々彰，鴨下渚，兼丸祐紀，本間正充，安井学
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] ヌクレオチド除去修復は酸化的クラスターDNA損傷によって誘発される突然変異を抑制する2015
- Author(s)
  佐々彰，鴨下渚，兼丸祐紀，本間正充，安井学
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Effect of nucleotide excision repair deficiency on mutagenesis induced by clustered 7,8-dihydro-8-oxoguanine in human cells.2015
- Author(s)
  Sassa A, Kamoshita N, Kanemaru Y, Honma M, Yasui M.
- Organizer
  Zing conference: Genomic Integrity 2015
- Place of Presentation
  ケアンズ
- Year and Date
  2015-07-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA損傷１分子の部位特異的なゲノム導入とその遺伝的影響の解析2015
- Author(s)
  安井学，佐々彰，鴨下渚，本間正充
- Organizer
  宇宙生物科学会
- Place of Presentation
  東京
- Year and Date
  2015-09-26
- Invited
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Mutation analysis of site-specific brominated DNA adducts located in the genome of human lymphoblastoid cells2013
- Author(s)
  Yasui M, Kanemaru Y, Kamoshita N, Sassa A, and Honma M
- Organizer
  Mammalian DNA Repair in Gordon Research Conferences
- Place of Presentation
  Ventura, USA
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] Mutation analysis of site-specific brominated DNA adducts located in the genome of human lymphoblastoid cells2013
- Author(s)
  Manabu Yasui, Yuki Kanemaru, Nagisa Kamoshita, Akira Sassa, and Masamitsu Honma
- Organizer
  Mammalian DNA Repair in Gordon Research Conferences
- Place of Presentation
  Ventura
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] Phenylalanine 171 of human DNA polymerase kappa is a molecular brake for translesion DNA synthesis across benzo[a]pyrene adducts2013
- Author(s)
  A.Sassa, T. Suzuki, Y. Kanemaru, N. Niimi, H. Fujimoto, A. Katafuchi, P. Gruz, M. Yasui, R. C. Gupta, F. Johnson, T. Ohta, M. Honma, N. Adachi and T. Nohmi
- Organizer
  44th Environmental Mutagenesis and Genomics Society
- Place of Presentation
  Monterey, California, U.S.A.
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] DNA付加体を部位特異的に含むDNAオリゴマーの生化学的構築とその突然変異誘発機構の解析2013
- Author(s)
  安井学
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山市
- Invited
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA付加体による突然変異誘発頻度はゼロにはならない2013
- Author(s)
  安井学，鴨下渚，兼丸祐紀，本間正充
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA付加体１分子による遺伝子変異誘発性2013
- Author(s)
  安井学，鴨下渚，本間正充
- Organizer
  日本放射線影響学会第56回大会
- Place of Presentation
  青森市
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] 遺伝毒性には閾値が無いことの証明2013
- Author(s)
  安井学，鴨下渚，本間正充
- Organizer
  日本リスク研究学会第26回年次大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] 極低線量暴露を想定した新しいDNA 付加体1分子による遺伝子変異解析系の基礎的研究2012
- Author(s)
  安井学,鴨下渚,本間正充
- Organizer
  日本放射線影響学会第55回大会
- Place of Presentation
  仙台市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] ゲノムの特定部位に導入させたブロモ化DNA付加体の突然変異誘発能の解析2012
- Author(s)
  兼丸祐紀，鴨下渚，佐々彰，本間正充，安井学
- Organizer
  日本環境変異原学会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] 極低線量暴露を想定した新しいDNA付加体１分子による遺伝子変異解析系の基礎的研究2012
- Author(s)
  安井学，鴨下渚，本間正充
- Organizer
  日本放射線影響学会
- Place of Presentation
  仙台市
- Invited
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] ゲノムの特定部位に導入させたブロモ化DNA 付加体の突然変異誘発能の解析2012
- Author(s)
  兼丸祐紀,鴨下渚,佐々彰,本間正充,安井学
- Organizer
  日本環境変異原学会第41回大会
- Place of Presentation
  静岡市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] Miscoding properties of brominated DNA adducts catalyzed by human DNA polymerases2011
- Author(s)
  Yasui M, Sassa A, Ohta T, Nohmi T, and Honma M
- Organizer
  UKEMS / Dutch EMS-sponsored Workshop on Biomarker of Exposure and Oxidative DNA Damage
- Place of Presentation
  ミュンスター,ドイツ
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] 8-クロログアニンDNA 付加体を含むオリゴマーの構築とその誤塩基対形成機構に関する研究2011
- Author(s)
  安井学,佐々彰,鴨下渚,松田知成,太田敏博,能美健彦,本間正充
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] 8-クロログアニンDNA付加体を含むオリゴマーの構築とその誤塩基対形成機構に関する研究2011
- Author(s)
  安井　学
- Organizer
  日本環境変異原学会第40回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] Miscoding properties of brominated DNA adducts catalyzed by human DNA polymerases.2011
- Author(s)
  Manabu Yasui
- Organizer
  Workshop on Biomarker of Exposure and Oxidative DNA Damage in Germany
- Place of Presentation
  ドイツ,ミュンスター
- Year and Date
  2011-03-28
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] ゲノムDNAに導入した1 分子のDNA 付加体の運命2011
- Author(s)
  安井学,鴨下渚,本間正充
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] Genotoxic thresholds : identification of mutations in vivo and mechanistic studies in vitro2011
- Author(s)
  T. Nohmi, K. Masumura, P Gruz, N. Toyoda-Hokaiwado, M. Takamune, N. Niimi, T. Suzuki, Y. Kanemaru, M. Yasui, M. Yamada, M. Honma, N. Adachi and A. Nishikawa
- Organizer
  2nd International Symposium on Genotoxic and Carcinogenic Thresholds
- Place of Presentation
  Tokyo
- Year and Date
  2011-11-23
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] ゲノムDNAに導入した1分子のDNA付加体の運命2011
- Author(s)
  安井学, 鴨下渚, 本間正充
- Organizer
  第34回日本分子生物学会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] gpt delta トランスジェニックラットを用いたライフステージ(週齢)を考慮したアクリルアミドの遺伝毒性評価2011
- Author(s)
  小山直己,安井学,木村葵,高見成昭, 鈴木拓也,増村健一,能美健彦,増田修一,木苗直秀,松田知成,今井俊夫,本間正充
- Organizer
  第38回日本トキシコロジー学会学術年会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] DNA付加体を含む修飾DNAオリゴマーの生化学的構築法の最適化2010
- Author(s)
  安井学
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22241016
[Presentation] DNA2 本鎖切断修復に対する低線量放射線等の環境ストレスの影響2010
- Author(s)
  本間正充,安井学,堀端克良,鈴木哲矢,谷田貝文夫
- Organizer
  第33回日本分子生物学会年会・第83 回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] Miscoding events during DNA synthesis past brominated DNA adducts2010
- Author(s)
  Sassa A, Ohta T, Nohmi T, Honma M, and Yasui M
- Organizer
  The 2nd Asian Conference of Environmental Mutagen
- Place of Presentation
  パタヤ,タイ
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] DNA 付加体を含む修飾DNA オリゴマーの生化学的構築法の最適化2010
- Author(s)
  安井学, 佐々彰, 鴨下渚, 太田敏博, 松田知成, 能美健彦, 本間正充
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] 臭素化DNA 付加体の誤塩基対形成機構2010
- Author(s)
  佐々彰, 太田敏博, 能美健彦, 本間正充, 安井学
- Organizer
  日本環境変異原学会第39回大会
- Place of Presentation
  つくば市
- Data Source
  KAKENHI-PROJECT-22710068
[Presentation] ヒトリンパ球細胞のゲノム内に導入させた8-オキソグアニン1 分子の突然変異誘発能2008
- Author(s)
  安井学,本間正充
- Organizer
  日本環境変異原学会第37回大会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] Emergence and Fate of Micronuclei by Fluorescent Live Cell Imaging Analysis.2008
- Author(s)
  Yasui, M., Koyama, N., Koizumi, T., Sakuraba, M., Sakamoto, H., Takashima, Y., Sugimoto, K., Hayashi, M., and Honma, M.
- Organizer
  American Association of Cancer Research
- Place of Presentation
  アメリカ合衆国カリフォルニア州
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] ヒトリンパ球細胞のゲノム内に導入させた8-オキソグアニン1分子の突然変異誘発能2008
- Author(s)
  安井学, 本間正充
- Organizer
  第37回日本環境変異原学会
- Place of Presentation
  那覇市
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] 一酸化窒素によって形成するDNA付加体の誤塩基対形成メカニズム.2008
- Author(s)
  安井学,鈴木奈緒美,澁谷眞也,本間正充
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会
- Place of Presentation
  神戸市
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] Translesion synthesis past 2'-deoxyinosine, a major nitric oxide-induced DNA adduct2007
- Author(s)
  Yasui, M., Suenaga, E., Koyama, N., Masutani, C., Hanaoka, F., Gruz, P., Shibutani, S., Nohmi, T.,Hayashi, M., and Honma, M.
- Organizer
  by human DNA polymerase η and κ. 1st ACEM/36th JEMS
- Place of Presentation
  北九州市
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] Mechanism of translesion synthesis past an equine estrogen-DNA adduct by Y-family DNA polymerases.2007
- Author(s)
  安井学
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜市
- Year and Date
  2007-12-13
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] Translesion synthesis past 2'-deoxyinosine, a major nitric oxide-induced DNA adduct, by human DNA polymerases η and κ.2007
- Author(s)
  Manabu Yasui
- Organizer
  International Conference on Environmental Mutagens
- Place of Presentation
  北九州市
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] Mechanism of translesion synthesis past an equine estrogen-DNA adduct by Y-family DNA polymerases2007
- Author(s)
  Yasui, M., Suzuki, N., Liu, X., Okamoto, Y., Kim, S.Y., Laxmi, Y.R., and Shibutani, S
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-19710059
[Presentation] ゲノムの特定部位に配置させたクラスターDNA損傷の数的遺伝毒性影響
- Author(s)
  佐々彰，鴨下渚，兼丸祐紀，本間正充，安井学
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] DNA塩基損傷１分子を部位特異的にもつプラスミドの作製とヒト細胞におけるTLS解析
- Author(s)
  長野聖也，東垣由夏，佐々彰，川西優喜，安井学，高村岳樹，八木孝司
- Organizer
  第43回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2014-11-04 – 2014-11-05
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] 部位特異的にゲノム内に導入したDNA付加体の遺伝的影響
- Author(s)
  安井　学
- Organizer
  第43回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2014-11-04 – 2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] ゲノムの特定部位に配置させたクラスターDNA損傷の数的遺伝毒性影響
- Author(s)
  佐々彰，鴨下渚，兼丸祐紀，本間正充，安井学
- Organizer
  第43回日本環境変異原学会
- Place of Presentation
  東京
- Year and Date
  2014-11-04 – 2014-11-05
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Tracing the fate of site-specifically introduced DNA adducts in the human genome.
- Author(s)
  Honma M, Yasui M, Kanemaru Y, Kamoshita N, Suzuki T, Arakawa T
- Organizer
  4th Asian Conference on Environmental Mutagens
- Place of Presentation
  Kolkata, India
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25281022
[Presentation] Demonstration of non-threshold of 8-oxoG inducing gene mutation by targeted mutagenesis.
- Author(s)
  Honma M, Yasui M, Kanemaru Y, Kamoshita N, Suzuki T, Arakawa T
- Organizer
  43rd European Environmental Mutagen Society annual meeting
- Place of Presentation
  Lancaster, UK
- Year and Date
  2014-07-06 – 2014-07-10
- Data Source
  KAKENHI-PROJECT-25281022

1. NOHMI Takehiko (30150890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. MASUMURA Kenichi (40291116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. SAJI Tetsuya (20573950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. TOYODA Naomi (70381853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. GRUZ Petr (10321853)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. Takeda Shunichi (60188191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. Suzuki Ai (40463781)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 佐々彰 (10738347)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
9. 廣田耕志 (00342840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 笹沼博之 (00531691)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. Brown John (90583188)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 津田雅貴 (00734104)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. Honma Masamitsu

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
14. NAKAZAWA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yasui Manabu 安井 学

YASUI Manabu 安井 学

安井 学 ヤスイ マナブ

Research Projects

Research Products

Co-Researchers

透析膜を利用した新しい代謝活性化システムによるDNA付加体の形成と同定Principal Investigator

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Quantum chemical challenge to elucidate the functional mechanism of base sequence specificity deciding removal of the DNA damage

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Establishment of Novel Bioassays for in vivo Genotoxicity Prediction and Mechanism Characterization

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Site-specific gene mutagenesis involving a single DNA adduct in vivoPrincipal Investigator

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Studies on mechanisms underlying genotoxic thresholds through genetic modification of DNA polymerase zeta

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Development of a single DNA adduct-caused gene mutation assay as a model of low-dose exposurePrincipal Investigator

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Mutation mechanism of a single DNA adduct embedded in human genomeof TK6 cellsPrincipal Investigator

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ホルムアルデヒドによって誘発されるDNA付加体の定量法の開発Principal Investigator

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[Journal Article] FTO regulates the DNA damage response via effects on cell-cycle progression2023

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[Journal Article] Potent mutagenicity of an azide, 3-azido-1,2-propanediol, in human TK6 cells2022

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[Journal Article] Follow-up genotoxicity assessment of Ames-positive/equivocal chemicals using the improved thymidine kinase gene mutation assay in DNA repair-deficient human TK6 cells2021

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[Journal Article] Dynamics of Water Molecules around the DNA Lesions2021

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[Journal Article] Potential Analysis of the Hydration Layer around the Injured DNA2020

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[Journal Article] Enhancing the sensitivity of the thymidine kinase assay by using DNA repair-deficient human TK6 cells.2020

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Yasui Manabu 安井学

YASUI Manabu 安井学

安井学ヤスイマナブ