SHIMIZU Kazuharu 清水一治

Researcher Number	50456836
Other IDs
Affiliation (based on the past Project Information) *help	2014 – 2016: 京都大学, 薬学研究科(研究院), 教授 2010: Kyoto University, 薬学研究科, 教授 2009 – 2010: Kyoto University, 薬学研究科, 客員教授 2008: Kyoto University, 薬学研究科, 教授
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Digestive surgery
Keywords	Principal Investigator microRNA / 乳がん / マイクロアレイ / マイクロRNA / 乳癌 Except Principal Investigator 抗体作成 / 抗体治療 / 食道癌 / FGFRL1 / 癌

Research on the treatment of esophageal cancer with anti-human fibroblast growth factor receptor like-1
- Principal Investigator
  
  SHIMADA Yutaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Kyoto University
Application of microRNA profilling to breast cancer diagnosis and therapyPrincipal Investigator
- Principal Investigator
  
  SHIMIZU Kazuharu
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University

All 2017 2016 2015 2014 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Role of fibroblast growth factor receptors in esophageal squamous cell carcinoma2016
- Author(s)
  Shimada Y, Okumura T, Takei Y, Watanabe K, Nagata T, Hori T, Tsuchiya S, Tsukada K, Shimizu K
- Journal Title
  
  Esophagus
  
  Volume: 13 Issue: 1 Pages: 30-41
- DOI
  10.1007/s10388-015-0486-4
- NAID
  40020705045
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26293302
[Journal Article] Expression analysis of fibroblast growth factor receptor-like 1 (FGFRL1) in esophageal squamous cell carcinoma2014
- Author(s)
  Shimada Y, Okumura T, Nagata T, Hashimoto I, Sawada S, Yoshida T, Fukuoka J, Shimizu K, Tsukada K
- Journal Title
  
  Esopagus
  
  Volume: 11 Issue: 1 Pages: 48-53
- DOI
  10.1007/s10388-013-0394-4
- NAID
  40020229726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26293302
[Journal Article] MicroRNA-203 inhibits the progression of esophageal squamous cell carcinoma with restored epithelial tissue architecture in vivo.2014
- Author(s)
  Okumura T, Shimada Y, Moriyama M, Takei Y, Omura T, Sekine S, Nagata T, Shimizu K, Tsukada K.
- Journal Title
  
  Int J Oncol
  
  Volume: 44 Issue: 6 Pages: 1923-1932
- DOI
  10.3892/ijo.2014.2365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591920, KAKENHI-PROJECT-26293302
[Journal Article] MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma.2011
- Author(s)
  Imanaka Y, Tsuchiya S, Sato F, Shimada Y, Shimizu K, Tsujimoto G
- Journal Title
  
  J Hum Genet. 56
  
  Pages: 270-276
- NAID
  10030658712
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390342
[Journal Article] MicroRNAs and epigenetics.2011
- Author(s)
  Sato F, Tsuchiya S, Meltzer SJ, Shimizu K.
- Journal Title
  
  FEBS Journal
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390342
[Journal Article] Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing.2010
- Author(s)
  Ruike Y, Imanaka Y, Sato F, Shimizu K, Tsujimoto G.
- Journal Title
  
  BMC Genomics.
  
  Volume: 11 Pages: 137-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390342
[Journal Article] Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing.2010
- Author(s)
  Ruike Y, Imanaka Y, Sato F, Shimizu K, Tsujimoto G
- Journal Title
  
  BMC Genomics. 11
  
  Pages: 137-137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390342
[Journal Article] 特集・がん化学療法個別化の現状と展望、トランスクリプトーム解析に基づくがん化学療法の最適化とゲノム創薬2008
- Author(s)
  佐藤史顕, 辻本豪三, 清水一治
- Journal Title
  
  医薬ジャーナル 44
  
  Pages: 104-108
- Data Source
  KAKENHI-PROJECT-20390342
[Journal Article] 特集・がん化学療法個別化の現状と展望、トランスクリプトーム解析に基づくがん化学療法の最適化とゲノム創薬。2008
- Author(s)
  佐藤史顕、清水一治、辻本豪三。
- Journal Title
  
  医薬ジャーナル Vol.44, No.12
  
  Pages: 104-108
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Circulating microRNA expression profiles as a novel diagnostic biomarker for esophageal squamous cell carcinoma2017
- Author(s)
  Shimada Y, Takei Y, Okumura T, Nagata T, Fujinami H, Arima M, Abe T, Niwa Y, Tajika M, Sudo T, Shimizu K
- Organizer
  108th Annual Meeting of the American Association for Cancer Research
- Place of Presentation
  Washington, DC
- Year and Date
  2017-03-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293302
[Presentation] Establishment of an esophageal small cell carcinoma cell line (TYUC-1)2015
- Author(s)
  Shimada Y, Okumura T, Takei Y, Watanabe K, Nagata T, Tsukada K, Yamane A, Nishiyama M, Hirasawa A, Shimizu K
- Organizer
  2015 annual meeting of American Association of Cancer Research
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293302
[Presentation] Trastuzumabによる細胞増殖抑制に関与するmicroRNAの同定及び機能解析2011
- Author(s)
  市川雄大、佐藤史顕、寺澤和哉、清水一治、辻本豪三
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  誌上発表
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] 乳癌におけるmiR-200b/a/429 clusterのEpigenetics発現調節と上皮間葉形質転換への関与2011
- Author(s)
  伊藤考晃、佐藤史顕、清水一治、辻本豪三
- Organizer
  日本薬学会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] 乳癌におけるmiR-200b/a/429 clusterのEpigenetics発現調節と上皮間葉形質転換への関与2011
- Author(s)
  伊藤考晃、佐藤史顕、清水一治、辻本豪三
- Organizer
  日本薬学会第131回年会
- Place of Presentation
  誌上発表
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Trastuzumabによる細胞増殖抑制に関与するmicroRNAの同定及び機能解析2011
- Author(s)
  市川雄大、佐藤史顕、寺澤和哉、清水一治、辻本豪三
- Organizer
  日本薬学会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] 4P-1187, Bioinformatic identification of tissue specific microRNA targets by mRNA expression profile.2010
- Author(s)
  Fujiwara T, Tsuchiya S, Sato F, Shimada Y, Tsujimoto G, Shimizu K
- Organizer
  日本分子生物学会、日本生化学会合同大会
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] #PA118、乳癌におけるエピジェネティクス調節されるマイクロRNAのゲノムワイド探索2009
- Author(s)
  佐藤史顕、類家慶直、伊藤考晃、辻本豪三、清水一治
- Organizer
  日本人類遺伝学会第54回大会
- Place of Presentation
  品川
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] #PAO32、microRNA-210の発現低下による細胞周期停止機能の破綻を介した食道扁平上皮癌細胞の細胞増殖抑制メカニズムの解明2009
- Author(s)
  土屋創健, 佐藤史顕, 藤原大, 嶋田裕, 辻本豪三, 清水一治
- Organizer
  日本人類遺伝学会第54回大会
- Place of Presentation
  品川
- Year and Date
  2009-09-23
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] #P-83乳がんにおけるエピジェネティクス調節を受けるマイクロRNAの探索2009
- Author(s)
  佐藤史顕、類家慶直、辻本豪三、清水一治
- Organizer
  日本エピジェネティクス研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Screening of epigenetically controlled microRNAs in breast cancer2009
- Author(s)
  佐藤史顕, 類家慶直, 辻本豪三, 清水一治
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Repeatability and comparability of microRNA microarray.2009
- Author(s)
  佐藤史顕, 土屋創健, 寺澤和哉, 辻本豪三, 清水一治
- Organizer
  アメリカ癌学会第100大会
- Place of Presentation
  Denver
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Symposium 4, " Key-technology in ADMETox Next-generation High-throughput Sequencer and DNA Microarray as ADME Research Tools2009
- Author(s)
  佐藤史顕, 清水一治
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] #P-83乳がんにおけるエピジェネティクス調節を受けるマイク・RNAの探索2009
- Author(s)
  佐藤史顕, 類家慶直, 辻本豪三, 清水一治
- Organizer
  日本エピジェネティクス研究会
- Place of Presentation
  東京
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Education Program 2、「ゲノム薬理学と個別化医療」EP2-2「発現プロファイルによるがんの個別化医療」2009
- Author(s)
  佐藤史顕、清水一治、辻本豪三
- Organizer
  日本人類遺伝学会第54回大会
- Place of Presentation
  品川
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Symposium 4, "Key-technology in ADMETox, Next-generation High-throughput Sequencer and DNA Microarray as ADME Research Tools2009
- Author(s)
  佐藤史顕, 清水一治
- Organizer
  日本薬物動態学会第24回年会
- Place of Presentation
  京都
- Year and Date
  2009-11-28
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] miR-X Contributes to Cisplatin Resistance of Esophageal Cancer cells.2009
- Author(s)
  今中由花子、土屋創健、佐藤史顕、嶋田裕、清水一治、辻本豪三
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Late-Breaking Abstract, #4P-1510 Reproducibility and Quantitivity of microRNA microarray2008
- Author(s)
  Fumiaki Sato, Soken Tsuchiya, Kazuya Terasawa, Gozoh Tsujimoto, Kazuharu Shimizu
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-20390342
[Presentation] Role of finbroblast growth factor receptors in esophageal squamous cell carcinoma
- Author(s)
  Shimada Y, Okumura T, Nagata T, Tsukada K, Shimizu K.
- Organizer
  2014 annual meeting of American Association of Cancer Research
- Place of Presentation
  San Diego (USA)
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-26293302

1. TSUCHIYA Soken (80423002)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. TOI Masakazu (10207516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TSUJIMOTO Gozoh (80172013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
4. SATO Fumikai (20467426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
5. UENO Takayuki (40452362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SHIMADA Yutaka (30216072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. ITOU Yuji (60223195)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MARUSAWA Hiroyuki (80324630)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. OHTSUJI Eigo (20244600)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. TSUKADA Kazuhiro (90171967)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
11. MATSUMOTO Osamu (10231599)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 武井義則 (30502455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
13. OKUMURA Tomoyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

SHIMIZU Kazuharu 清水 一治

Research Projects

Research Products

Co-Researchers

Research on the treatment of esophageal cancer with anti-human fibroblast growth factor receptor like-1

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Application of microRNA profilling to breast cancer diagnosis and therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Role of fibroblast growth factor receptors in esophageal squamous cell carcinoma2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Expression analysis of fibroblast growth factor receptor-like 1 (FGFRL1) in esophageal squamous cell carcinoma2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] MicroRNA-203 inhibits the progression of esophageal squamous cell carcinoma with restored epithelial tissue architecture in vivo.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-141 confers resistance to cisplatin-induced apoptosis by targeting YAP1 in human esophageal squamous cell carcinoma.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] MicroRNAs and epigenetics.2011

Author(s)

Journal Title

Data Source

[Journal Article] Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing.2010

Author(s)

Journal Title

Data Source

[Journal Article] Genome-wide analysis of aberrant methylation in human breast cancer cells using methyl-DNA immunoprecipitation combined with high-throughput sequencing.2010

Author(s)

Journal Title

Data Source

[Journal Article] 特集・がん化学療法個別化の現状と展望、トランスクリプトーム解析に基づくがん化学療法の最適化とゲノム創薬2008

Author(s)

Journal Title

Data Source

[Journal Article] 特集・がん化学療法個別化の現状と展望、トランスクリプトーム解析に基づくがん化学療法の最適化とゲノム創薬。2008

Author(s)

Journal Title

Data Source

[Presentation] Circulating microRNA expression profiles as a novel diagnostic biomarker for esophageal squamous cell carcinoma2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Establishment of an esophageal small cell carcinoma cell line (TYUC-1)2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Trastuzumabによる細胞増殖抑制に関与するmicroRNAの同定及び機能解析2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 乳癌におけるmiR-200b/a/429 clusterのEpigenetics発現調節と上皮間葉形質転換への関与2011

Author(s)

Organizer

Place of Presentation

SHIMIZU Kazuharu 清水一治